GO:0002246

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Name wound healing involved in inflammatory response
Categary Process
Go Slim No
Go Link GO:0002246
Unique Molecular Interactions 118
Total Molecular Interactions 158
Total Single Events 2250
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for wound healing involved in inflammatory response. They are ordered first by their pain relevance and then by number of times they were reported for wound healing involved in inflammatory response. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT161224 Ccl2 Positive_regulation of Ccr2 1 0.52 2.09 1.88
2 INT111221 MMEL1 Negative_regulation of HMOX1 1 0.01 1 1.16
3 INT231769 TNF Negative_regulation of Gene_expression of HMOX1 1 0.26 4.75 1.15
4 INT181434 Binding of Ccr2 and Ccl2 1 0.27 6.06 1.04
5 INT147474 Nfe2l2 Positive_regulation of Hmox1 1 0.43 0.38 0.9
6 INT81299 Ifng Positive_regulation of Gene_expression of Hmox1 1 0.52 0.75 0.76
7 INT99743 Olr1742 Regulation of Gene_expression of Hmox1 1 0.00 0 0.68
8 INT86519 Binding of Hmox1 and Hmox2 1 0.08 0.1 0.66
9 INT103868 IFNG Positive_regulation of Hmox1 1 0.09 0.83 0.65
10 INT99744 Calca Positive_regulation of Positive_regulation of Hmox1 1 0.48 0 0.64
11 INT103870 IRF6 Positive_regulation of Hmox1 1 0.14 0.83 0.64
12 INT81303 Tlr4 Positive_regulation of Gene_expression of Hmox1 1 0.03 0.55 0.56
13 INT270044 Il10 Positive_regulation of Positive_regulation of Hmox1 1 0.20 1.59 0.53
14 INT350076 Positive_regulation of Hmox1 Negative_regulation of Gene_expression of Ptger2 1 0.02 1.29 0.5
15 INT145435 Binding of CPOX and HMOX1 1 0.01 0.42 0.49
16 INT145434 Binding of HMOX1 and PTGS2 1 0.02 0.41 0.47
17 INT187100 Binding of Cd4 and Cd44 1 0.02 1.09 0.47
18 INT148466 Ccl4 Positive_regulation of Hmox1 1 0.28 0.06 0.47
19 INT242402 Negative_regulation of Bdkrb1 Positive_regulation of Hmox1 1 0.17 1.44 0.45
20 INT103871 Negative_regulation of IRF6 Positive_regulation of Hmox1 1 0.12 0.61 0.45
21 INT165677 NFE2L2 Negative_regulation of Positive_regulation of HMOX1 1 0.40 0.32 0.44
22 INT165678 NFE2L2 Negative_regulation of HMOX1 1 0.40 0.31 0.43
23 INT148548 Cd44 Positive_regulation of Regulation of NPEPPS 1 0.00 0.29 0.42
24 INT181448 Eae1 Positive_regulation of Gene_expression of Ccr2 1 0.04 4.98 0.42
25 INT148547 Cd44 Positive_regulation of NPEPPS 1 0.00 0.29 0.41
26 INT216881 Binding of Apoc4 and Hmox1 1 0.01 1.78 0.4
27 INT147473 Nfe2l2 Positive_regulation of Gene_expression of Hmox1 1 0.74 0.49 0.39
28 INT147472 co Positive_regulation of Gene_expression of Hmox1 1 0.01 0.57 0.36
29 INT181435 Binding of Ccr2 and Hand2 1 0.17 1.81 0.32
30 INT306107 Binding of CCL2 and Ccr2 1 0.06 0 0.28
31 INT91751 Binding of PTGS2 and Hmox1 1 0.00 0.21 0.27
32 INT270046 Ido1 Positive_regulation of Positive_regulation of Hmox1 1 0.15 0.8 0.27
33 INT216880 Apoc4 Positive_regulation of Hmox1 1 0.03 1.06 0.25
34 INT349652 Positive_regulation of Hmox1 Negative_regulation of Positive_regulation of Itk 1 0.01 0.85 0.25
35 INT350099 Gene_expression of Hmox1 Positive_regulation of Gene_expression of MRXS5 1 0.01 0.51 0.24
36 INT328228 Binding of Cpox and Hmox1 1 0.03 0.83 0.23
37 INT350065 Gene_expression of Hmox1 Negative_regulation of Gene_expression of Tlr4 1 0.18 0.35 0.22
38 INT260397 Positive_regulation of Hmox1 Positive_regulation of Gene_expression of Adipoq 1 0.37 0.78 0.22
39 INT103867 SFTPA1 Positive_regulation of Hmox1 1 0.00 0.35 0.22
40 INT64340 Zc3h15 Negative_regulation of Hmox1 1 0.12 0.47 0.22
41 INT350078 Hmox1 Negative_regulation of Gene_expression of Ptger2 1 0.02 0.35 0.22
42 INT103869 Binding of IRF6 and Positive_regulation of Hmox1 1 0.10 0.27 0.21
43 INT349647 Eif2ak1 Positive_regulation of Positive_regulation of Hmox1 1 0.00 1.07 0.2
44 INT350096 Hmox1 Negative_regulation of Gene_expression of MRXS5 1 0.01 0.32 0.2
45 INT266646 HMOX2 Regulation of Gene_expression of Hmox1 1 0.00 0.87 0.2
46 INT349646 Eif2ak1 Regulation of Gene_expression of Hmox1 1 0.00 0.78 0.2
47 INT260394 Positive_regulation of Hmox1 Positive_regulation of Adipoq 1 0.37 0.78 0.19
48 INT181440 Binding of Ccr2 and Eae1 1 0.03 1.3 0.19
49 INT199192 Gnat3 Positive_regulation of Hmox1 1 0.27 0.23 0.19
50 INT81296 Positive_regulation of Pparg Regulation of Gene_expression of Hmox1 1 0.25 0.17 0.17
51 INT350072 Ptger2 Positive_regulation of Hmox1 1 0.02 0.2 0.15
52 INT231757 TLR4 Positive_regulation of Negative_regulation of HMOX1 1 0.26 1.37 0.15
53 INT216882 Tlr4 Positive_regulation of Hmox1 1 0.17 0.19 0.15
54 INT350081 Pik3r1 Positive_regulation of Hmox1 1 0.07 0.2 0.15
55 INT350069 Prkaca Positive_regulation of Hmox1 1 0.05 0.2 0.15
56 INT199195 Gnat3 Regulation of Transcription of Hmox1 1 0.24 0.12 0.14
57 INT295267 Binding of Hmox1 and Gtf3a 1 0.01 0.49 0.13
58 INT295261 Binding of Hmox1 and Nfe2l2 1 0.17 0.49 0.13
59 INT295264 Positive_regulation of Binding of Hmox1 and Nfe2l2 1 0.25 0.5 0.13
60 INT231761 TNF Negative_regulation of HMOX1 1 0.19 1.2 0.12
61 INT231764 TLR4 Negative_regulation of HMOX1 1 0.27 1.54 0.11
62 INT231768 Binding of HMOX1 and TLR4 1 0.23 0.95 0.11
63 INT231772 TNF Positive_regulation of Gene_expression of HMOX1 1 0.21 0.96 0.1
64 INT231773 IRF6 Negative_regulation of Gene_expression of HMOX1 1 0.06 1.27 0.09
65 INT204899 Tlr4 Positive_regulation of Cd44 1 0.23 0.09 0.09
66 INT204885 Tlr4 Negative_regulation of Positive_regulation of Cd44 1 0.21 0.09 0.09
67 INT204889 Tlr4 Negative_regulation of Cd44 1 0.10 0.09 0.09
68 INT201456 Hmox1 Positive_regulation of Gene_expression of Bcl2 1 0.06 0.74 0.08
69 INT260392 Hmox1 Positive_regulation of Adipoq 1 0.32 0.65 0.07
70 INT244290 Il6 Positive_regulation of Hmox1 1 0.38 0.09 0.07
71 INT244291 Nos2 Positive_regulation of Positive_regulation of Hmox1 1 0.34 0.07 0.07
72 INT231760 TNF Positive_regulation of Protein_catabolism of HMOX1 1 0.31 0.41 0.06
73 INT349645 Eif2ak1 Positive_regulation of Hmox1 1 0.00 0.18 0.05
74 INT231758 IRF6 Regulation of Gene_expression of HMOX1 1 0.08 0.23 0.05
75 INT231766 TLR4 Negative_regulation of Gene_expression of HMOX1 1 0.28 0.71 0.05
76 INT231771 Binding of HMOX1 and TNF 2 0.14 1.41 0.04
77 INT352612 Trp53 Negative_regulation of Cd44 1 0.24 1.01 0.04
78 INT231759 IL10 Positive_regulation of Gene_expression of HMOX1 1 0.06 0.7 0.04
79 INT349648 Eif2ak1 Positive_regulation of Gene_expression of Hmox1 1 0.00 0.17 0.04
80 INT227333 Il2 Positive_regulation of Hmox1 1 0.05 0.93 0.04
81 INT231775 TLR4 Regulation of Gene_expression of HMOX1 1 0.29 0.68 0.04
82 INT231774 Gene_expression of TLR4 Positive_regulation of Gene_expression of HMOX1 1 0.30 0.68 0.04
83 INT231762 TLR4 Positive_regulation of Gene_expression of HMOX1 1 0.30 0.68 0.04
84 INT335492 CREM Positive_regulation of Transcription of HMOX1 1 0.00 0.9 0.03
85 INT350071 Hmox1 Regulation of Tlr4 1 0.22 0.33 0.03
86 INT176543 Binding of Cd44 and Spp1 2 0.31 0.57 0
87 INT325945 Binding of Cd44 and Ezr 1 0.25 0.39 0
88 INT229818 Fos Positive_regulation of Hmox1 1 0.43 0.37 0
89 INT350098 Gene_expression of PSEN2 Positive_regulation of Gene_expression of Hmox1 1 0.39 0 0
90 INT260395 Positive_regulation of Adipoq Negative_regulation of Gene_expression of Hmox1 1 0.34 1.4 0
91 INT259670 CSE Positive_regulation of Hmox1 1 0.06 0.97 0
92 INT330735 GSTK1 Regulation of HMOX1 1 0.08 0.25 0
93 INT260398 Dclk2 Regulation of Gene_expression of Hmox1 1 0.01 1.02 0
94 INT260393 Hmox1 Regulation of Positive_regulation of Bcl2 1 0.22 0.86 0
95 INT328775 Binding of Cd44 and Epcam 1 0.08 1.34 0
96 INT301906 Binding of HMOX1 and HSD11B1 1 0.05 2.41 0
97 INT350068 Positive_regulation of Hmox1 Negative_regulation of Gene_expression of Ptgs2 1 0.03 0.16 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for wound healing involved in inflammatory response. They are ordered first by their pain relevance and then by number of times they were reported in wound healing involved in inflammatory response. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT73982 Gene_expression of Hmox1 141 0.78 119.43 32.17
2 INT86780 Positive_regulation of Hmox1 145 0.70 117.09 31.18
3 INT102545 Gene_expression of Ccr2 42 0.78 61.43 19.81
4 INT80223 Positive_regulation of Hmox1 128 0.68 77.71 17.64
5 INT76406 Gene_expression of Hmox1 140 0.78 85.86 17.15
6 INT80228 Positive_regulation of Gene_expression of Hmox1 68 0.70 62.88 14.01
7 INT116528 Gene_expression of HMOX1 106 0.78 86.13 12.8
8 INT111223 Positive_regulation of HMOX1 47 0.70 39.14 10.92
9 INT161222 Positive_regulation of Ccr2 13 0.55 13.77 8.89
10 INT82450 Negative_regulation of Hmox1 33 0.55 19.07 8.12
11 INT81293 Positive_regulation of Gene_expression of Hmox1 53 0.70 41.54 7.25
12 INT102548 Negative_regulation of Ccr2 14 0.59 19.84 7.22
13 INT82451 Negative_regulation of HMOX1 18 0.51 13.29 5.74
14 INT116527 Positive_regulation of Gene_expression of HMOX1 29 0.70 25.79 4.87
15 INT67144 Gene_expression of Cd44 17 0.76 8.94 4.48
16 INT48411 Gene_expression of Cd44 35 0.77 27.05 4.29
17 INT64338 Negative_regulation of Hmox1 16 0.56 12.72 4.2
18 INT161221 Positive_regulation of Positive_regulation of Ccr2 3 0.50 4.55 3.98
19 INT97096 Regulation of Hmox1 18 0.61 6.42 3.9
20 INT80224 Regulation of Hmox1 19 0.32 10.53 3.52
21 INT135773 Negative_regulation of Gene_expression of HMOX1 31 0.53 28.31 3.32
22 INT102634 Transcription of Hmox1 22 0.62 4.5 3.3
23 INT127904 Negative_regulation of Gene_expression of Hmox1 11 0.42 9.54 2.8
24 INT81291 Regulation of Gene_expression of Hmox1 11 0.60 8.78 2.46
25 INT146504 Regulation of Ccr2 5 0.39 3.58 2.21
26 INT99742 Negative_regulation of Gene_expression of Hmox1 12 0.58 9.94 1.77
27 INT181341 Binding of Ccr2 8 0.32 6.47 1.77
28 INT102550 Positive_regulation of Gene_expression of Ccr2 6 0.69 4.53 1.67
29 INT80227 Regulation of Gene_expression of Hmox1 12 0.44 11.04 1.61
30 INT91232 Regulation of Positive_regulation of Hmox1 5 0.45 2.43 1.55
31 INT103305 Positive_regulation of Positive_regulation of Hmox1 8 0.49 4.81 1.49
32 INT100420 Regulation of HMOX1 10 0.35 6.68 1.48
33 INT173716 Positive_regulation of Cd44 7 0.44 4.65 1.45
34 INT181373 Negative_regulation of Gene_expression of Ccr2 5 0.59 5.92 1.44
35 INT165680 Transcription of HMOX1 7 0.71 11.2 1.41
36 INT127283 Regulation of Gene_expression of HMOX1 14 0.61 11.8 1.28
37 INT91320 Localization of Hmox1 8 0.81 4.06 1.28
38 INT123924 Positive_regulation of Gene_expression of Cd44 2 0.46 1.11 1.25
39 INT115831 Transcription of Hmox1 16 0.66 5.31 1.14
40 INT199187 Localization of Hmox1 2 0.78 3.36 1.11
41 INT135390 Binding of Cd44 3 0.45 1.91 1.09
42 INT116529 Binding of HMOX1 10 0.47 15.38 1.04
43 INT105445 Localization of HMOX1 5 0.71 3.11 0.98
44 INT201454 Positive_regulation of Positive_regulation of Hmox1 6 0.35 5.2 0.94
45 INT148461 Positive_regulation of Transcription of Hmox1 6 0.33 1.83 0.93
46 INT135392 Localization of Cd44 1 0.75 1.74 0.93
47 INT161223 Negative_regulation of Positive_regulation of Ccr2 1 0.43 0.83 0.81
48 INT82568 Protein_catabolism of Hmox1 5 0.86 1.03 0.79
49 INT204842 Positive_regulation of Cd44 9 0.49 6.6 0.77
50 INT187096 Negative_regulation of Cd44 6 0.30 5.92 0.7
51 INT187087 Binding of Cd44 5 0.47 2.79 0.66
52 INT287003 Negative_regulation of Positive_regulation of Hmox1 2 0.34 3.1 0.63
53 INT288158 Negative_regulation of Gene_expression of Cd44 5 0.30 5.73 0.59
54 INT165681 Positive_regulation of Transcription of HMOX1 2 0.69 4.29 0.53
55 INT236350 Transcription of Ccr2 2 0.72 3.59 0.49
56 INT270030 Negative_regulation of Positive_regulation of Hmox1 3 0.30 2.49 0.47
57 INT272877 Localization of Ccr2 2 0.75 1.68 0.46
58 INT157157 Negative_regulation of Localization of HMOX1 1 0.37 0.74 0.37
59 INT340642 Regulation of Gene_expression of Ccr2 1 0.62 2.26 0.35
60 INT281659 Regulation of Transcription of HMOX1 2 0.27 2.12 0.33
61 INT216879 Binding of Hmox1 4 0.36 2.82 0.31
62 INT135772 Regulation of Positive_regulation of HMOX1 3 0.39 1.52 0.29
63 INT103070 Negative_regulation of Gene_expression of Cd44 1 0.38 0.43 0.29
64 INT328227 Positive_regulation of Localization of Hmox1 1 0.45 0.67 0.28
65 INT91231 Binding of Hmox1 4 0.36 0.29 0.27
66 INT203080 Negative_regulation of Cd44 1 0.14 0.3 0.24
67 INT201453 Protein_catabolism of Hmox1 3 0.95 4.25 0.23
68 INT350048 Negative_regulation of Regulation of Hmox1 1 0.30 0.37 0.23
69 INT48656 Positive_regulation of Gene_expression of Cd44 7 0.69 5.93 0.21
70 INT214464 Regulation of Gene_expression of Cd44 3 0.34 2.95 0.17
71 INT115829 Regulation of Transcription of Hmox1 1 0.35 1.03 0.17
72 INT201467 Protein_catabolism of HMOX1 2 0.77 0.83 0.13
73 INT288160 Regulation of Cd44 1 0.42 0.67 0.1
74 INT236358 Regulation of Transcription of Ccr2 1 0.24 1 0.09
75 INT115824 Positive_regulation of Transcription of Hmox1 3 0.45 0.43 0.06
76 INT293311 Positive_regulation of Positive_regulation of HMOX1 3 0.69 1.99 0.04
77 INT200859 Transcription of Cd44 2 0.41 0.71 0.04
78 INT350052 Positive_regulation of Negative_regulation of Hmox1 1 0.35 0.34 0.04
79 INT204861 Localization of Cd44 1 0.46 0.06 0.03
80 INT299521 Regulation of Cd44 1 0.12 0.36 0
81 INT235270 Positive_regulation of Binding of Cd44 1 0.26 1.11 0
82 INT337766 Phosphorylation of Hmox1 1 0.79 0.08 0
83 INT301984 Negative_regulation of Positive_regulation of Cd44 1 0.17 1.28 0
84 INT337767 Positive_regulation of Phosphorylation of Hmox1 1 0.49 0.08 0
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