GO:0002282

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Name microglial cell activation involved in immune response
Categary Process
Go Slim No
Go Link GO:0002282
Unique Molecular Interactions 665
Total Molecular Interactions 1031
Total Single Events 4541
Pain Genes Associated 20

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for microglial cell activation involved in immune response. They are ordered first by their pain relevance and then by number of times they were reported for microglial cell activation involved in immune response. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT179502 Binding of Cd14 and Tlr4 29 0.39 13.77 5.73
2 INT95068 Tlr4 Positive_regulation of IL1B 1 0.03 4.54 5.6
3 INT182124 Binding of IRF6 and TLR4 14 0.10 16.11 4.65
4 INT61733 Tlr4 Positive_regulation of Gene_expression of Tnf 3 0.26 1.99 2.36
5 INT164784 Il6 Positive_regulation of Gene_expression of Cx3cr1 1 0.47 2.37 1.98
6 INT264953 Binding of POMC and TLR4 1 0.03 0.89 1.96
7 INT157767 Binding of TLR4 and LY96 8 0.54 4.05 1.95
8 INT157459 Binding of CX3CR1 and CX3CL1 1 0.32 2.12 1.7
9 INT215100 Binding of Hmgb1 and Tlr4 5 0.29 3.21 1.68
10 INT215096 Binding of Hmgb1 and Tlr2 9 0.38 11.61 1.61
11 INT79778 Tlr4 Positive_regulation of Localization of TNF 4 0.08 4.21 1.61
12 INT254205 Binding of Myd88 and Tlr4 12 0.19 3.17 1.54
13 INT294775 IRF6 Positive_regulation of TLR4 6 0.08 2.04 1.32
14 INT78066 Tlr4 Positive_regulation of Localization of Il6 5 0.03 0.76 1.25
15 INT161507 Tlr4 Positive_regulation of Gene_expression of Il1b 1 0.24 0.19 1.25
16 INT161508 Tlr4 Positive_regulation of Mapk14 2 0.19 0.46 1.24
17 INT151648 TLR4 Regulation of Gene_expression of ICAM1 1 0.00 2.86 1.24
18 INT161509 Tlr4 Positive_regulation of Mapk8 1 0.15 0.3 1.16
19 INT161510 Tlr4 Positive_regulation of Mapk1 1 0.14 0.3 1.16
20 INT185321 Tlr4 Positive_regulation of Gene_expression of Il6 5 0.14 1.97 1.15
21 INT89938 Tlr4 Positive_regulation of Gene_expression of TNF 6 0.25 1.3 1.12
22 INT167426 Tlr4 Positive_regulation of Localization of Gpt 1 0.25 1.26 1.1
23 INT130656 Tlr4 Positive_regulation of Cyba 1 0.00 0.05 1.09
24 INT130657 Negative_regulation of Tlr4 Positive_regulation of Cyba 1 0.00 0.05 1.09
25 INT182125 Binding of CD14 and TLR4 7 0.25 3.78 1.03
26 INT291377 Binding of CX3CR1 and Cx3cl1 2 0.36 3.57 1.02
27 INT140168 Binding of Cx3cl1 and Cx3cr1 2 0.31 1.55 0.98
28 INT145163 Tlr4 Positive_regulation of Localization of Nsfl1c 1 0.02 0.43 0.94
29 INT219154 Binding of HMGB1 and TLR4 2 0.17 4.45 0.93
30 INT336017 Vip Regulation of Tlr4 1 0.22 1.23 0.93
31 INT306327 Binding of Ly96 and Tlr4 1 0.10 1.83 0.91
32 INT343909 IgG Positive_regulation of Gene_expression of TLR4 1 0.04 3.49 0.91
33 INT221386 Tlr4 Positive_regulation of Gene_expression of IL8 6 0.14 3.53 0.9
34 INT276964 Binding of Tlr1 and Tlr2 11 0.24 4.22 0.89
35 INT120147 Tlr4 Positive_regulation of Tnf 3 0.39 2.14 0.89
36 INT168281 Tlr4 Positive_regulation of Phosphorylation of Mapk4 1 0.06 1.05 0.89
37 INT244323 Csf2 Positive_regulation of Gene_expression of Tlr4 1 0.23 1.93 0.85
38 INT343829 TLR1 Positive_regulation of TBCE 1 0.03 0.96 0.85
39 INT184114 Tlr4 Positive_regulation of Socs3 2 0.65 1.14 0.83
40 INT150733 Negative_regulation of Tlr3 Negative_regulation of Positive_regulation of Il1b 1 0.48 1.34 0.83
41 INT152236 Tlr4 Regulation of Gene_expression of Nos2 3 0.19 0.64 0.82
42 INT168648 Positive_regulation of Cx3cr1 Positive_regulation of Phosphorylation of Mapk14 1 0.35 1.51 0.8
43 INT276988 Binding of Tlr6 and Tlr2 11 0.26 4.89 0.79
44 INT168647 Cx3cr1 Positive_regulation of Phosphorylation of Mapk14 1 0.52 1.51 0.79
45 INT223753 Tlr4 Positive_regulation of Gene_expression of Il10 4 0.32 1.93 0.78
46 INT296787 Tbrs1 Positive_regulation of Gene_expression of Tlr9 1 0.06 1.37 0.78
47 INT152235 Mapk8 Positive_regulation of Localization of Tlr4 1 0.38 0.26 0.78
48 INT296797 Tlr9 Regulation of Positive_regulation of TNF 1 0.03 1.37 0.77
49 INT339495 Tlr4 Positive_regulation of Eif2ak2 1 0.21 0.58 0.77
50 INT296788 Tlr9 Regulation of Positive_regulation of Il1 1 0.07 1.37 0.77
51 INT194644 Tlr4 Positive_regulation of TNF 6 0.58 2.42 0.76
52 INT296792 Tlr9 Regulation of Gene_expression of Il6 1 0.06 1.36 0.76
53 INT284306 Tlr4 Positive_regulation of Adrb3 1 0.00 1.19 0.74
54 INT219274 Binding of Cx3cr1 and Cx3cl1 1 0.17 1.08 0.74
55 INT331599 Tlr9 Positive_regulation of Gene_expression of Il6 1 0.03 1.8 0.73
56 INT222432 Binding of Tlr4 and Cd14 1 0.02 0.74 0.71
57 INT89936 Tlr4 Positive_regulation of Il6 3 0.49 0.95 0.7
58 INT215098 Tlr4 Positive_regulation of Localization of Il6 3 0.18 1.18 0.69
59 INT280951 Tlr4 Positive_regulation of Localization of S100a8 1 0.01 1.09 0.69
60 INT252605 Ppig Positive_regulation of Gene_expression of Cx3cr1 1 0.09 1.81 0.69
61 INT164783 Positive_regulation of Mapk14 Regulation of Gene_expression of Cx3cr1 1 0.19 0.81 0.68
62 INT215093 Tlr4 Positive_regulation of Localization of Hmgb1 1 0.32 2.9 0.68
63 INT164782 Il6 Regulation of Gene_expression of Cx3cr1 1 0.27 0.79 0.67
64 INT306020 Binding of LBP and Tlr4 1 0.13 0.34 0.66
65 INT120144 Negative_regulation of Tlr4 Positive_regulation of Tnf 1 0.18 0.91 0.66
66 INT343851 Positive_regulation of Binding of IRF6 and TLR4 1 0.07 1.96 0.66
67 INT296790 Tlr9 Regulation of Bax 1 0.14 0.76 0.65
68 INT296785 Tlr9 Regulation of Bcl2 1 0.19 0.76 0.65
69 INT244320 Tlr4 Positive_regulation of Aliq1 3 0.04 4.51 0.64
70 INT339393 Tlr4 Positive_regulation of Nfkb1 1 0.24 2.06 0.61
71 INT237907 Tlr4 Positive_regulation of Gene_expression of Tlr2 7 0.40 5.85 0.6
72 INT276603 Il10 Positive_regulation of Gene_expression of Tlr4 1 0.12 0.49 0.6
73 INT140264 Tlr4 Positive_regulation of Nfkb1 1 0.00 0.23 0.59
74 INT140263 Negative_regulation of Tlr4 Positive_regulation of Nfkb1 1 0.00 0.23 0.59
75 INT275552 Tlr4 Positive_regulation of Gene_expression of Il1 1 0.00 1.28 0.59
76 INT212813 Tlr4 Positive_regulation of Nos2 3 0.34 0.89 0.57
77 INT162790 Binding of TLR4 and NOD2 1 0.36 0.51 0.57
78 INT236783 IRF6 Negative_regulation of Gene_expression of TLR4 1 0.01 1.17 0.57
79 INT306330 Cd14 Positive_regulation of Gene_expression of Tlr4 1 0.48 0.54 0.57
80 INT146871 Tlr4 Positive_regulation of Gene_expression of ROS1 2 0.00 1.16 0.56
81 INT313223 Binding of Cx3cr1 and Mcpt1 1 0.06 0.99 0.56
82 INT81303 Tlr4 Positive_regulation of Gene_expression of Hmox1 1 0.03 0.55 0.56
83 INT183695 Binding of Tlr3 and Ducm1 1 0.04 2.75 0.56
84 INT313224 Negative_regulation of Binding of Cx3cr1 and Mcpt1 1 0.07 0.99 0.56
85 INT94745 Tlr4 Positive_regulation of Transcription of Il1b 1 0.15 0.48 0.56
86 INT175323 Tlr4 Positive_regulation of Gene_expression of TLR2 1 0.02 0.31 0.56
87 INT120143 Tlr4 Negative_regulation of Gene_expression of Tnf 1 0.18 0.76 0.55
88 INT243056 Binding of LBP and Tlr4 1 0.00 1.11 0.55
89 INT310767 Tlr4 Regulation of Gene_expression of S100a8 1 0.02 0.7 0.54
90 INT210934 Gene_expression of Tlr4 Negative_regulation of Ccl2 1 0.47 0.69 0.54
91 INT354367 Binding of FGFR1 and Tlr4 1 0.01 1.23 0.53
92 INT253767 Binding of Hmgb1 and Tlr9 2 0.12 1.78 0.52
93 INT179503 Cd14 Regulation of Positive_regulation of Tlr4 1 0.38 0.58 0.52
94 INT343838 EDA Positive_regulation of TLR4 1 0.11 0.87 0.51
95 INT285911 Binding of TLR4 and Cd14 1 0.05 1.13 0.51
96 INT324523 Tlr4 Regulation of Gene_expression of PGE 1 0.23 1.98 0.51
97 INT179507 Tlr4 Positive_regulation of Tlr2 2 0.17 1.07 0.49
98 INT306019 Binding of Tlr4 and LY96 1 0.06 0.91 0.49
99 INT254119 Binding of Bcl2a1a and Tlr4 1 0.01 1.34 0.49
100 INT158599 Tlr3 Positive_regulation of Binding of Fas 1 0.55 0.86 0.48
101 INT209046 Slc11a1 Positive_regulation of Regulation of Tlr4 1 0.07 0.09 0.48
102 INT244319 Csf2 Positive_regulation of Positive_regulation of Tlr4 1 0.23 1.03 0.48
103 INT322264 Binding of MPZ and TLR4 1 0.18 1.68 0.47
104 INT233527 Tlr4 Positive_regulation of ADORA1 1 0.00 0.45 0.47
105 INT233503 Tlr4 Positive_regulation of Adora2b 1 0.06 0.45 0.47
106 INT284300 Tlr4 Positive_regulation of Gene_expression of Mir155 1 0.18 0.91 0.47
107 INT246938 Binding of Tlr4 and Tlr2 3 0.39 2.88 0.46
108 INT207141 Tlr4 Positive_regulation of Positive_regulation of Pawr 1 0.05 0.79 0.46
109 INT233508 Tlr4 Regulation of Gene_expression of Gpr18 1 0.04 0.45 0.46
110 INT310769 Pam Regulation of Tlr4 1 0.01 0.69 0.46
111 INT296795 Binding of Tlr9 and Tlr3 2 0.22 1.29 0.45
112 INT69163 Tlr4 Positive_regulation of Ptgs1 1 0.02 0.08 0.44
113 INT230461 Binding of TLR1 and TLR2 3 0.33 2.06 0.43
114 INT212810 Tlr4 Positive_regulation of Gene_expression of Nos2 1 0.03 0.74 0.43
115 INT247599 Tlr4 Positive_regulation of Gene_expression of App 1 0.17 0.39 0.42
116 INT308696 Binding of Tlr4 and Tlr4 1 0.00 0.34 0.42
117 INT336926 Mir341 Regulation of Tlr4 1 0.02 1.57 0.41
118 INT348790 Binding of MYD88 and Tlr4 1 0.35 1.84 0.4
119 INT238384 Tlr4 Positive_regulation of Prkca 1 0.06 0.81 0.4
120 INT295478 IRF6 Positive_regulation of Positive_regulation of TLR4 2 0.20 0.78 0.39
121 INT181080 Binding of Cx3cr1 and Darc 1 0.00 1.09 0.39
122 INT222418 Tlr4 Positive_regulation of Gene_expression of Il1a 1 0.00 0.31 0.39
123 INT152238 Mapk14 Positive_regulation of Localization of Tlr4 1 0.29 0.13 0.39
124 INT152237 Mapk1 Positive_regulation of Localization of Tlr4 1 0.33 0.13 0.39
125 INT81300 Tlr4 Positive_regulation of Gene_expression of Nos2 1 0.02 0.38 0.39
126 INT260744 Binding of Ecm1 and Tlr2 1 0.00 0.45 0.39
127 INT310697 Tlr4 Positive_regulation of Gene_expression of Ptger2 2 0.03 1.34 0.38
128 INT339504 Binding of Irak1 and Tlr4 1 0.08 0.12 0.38
129 INT204893 Regulation of Tlr4 Positive_regulation of gr 1 0.11 0.9 0.38
130 INT260746 Binding of TLR4 and Ecm1 1 0.02 0.44 0.38
131 INT147969 Binding of Ly86 and Tlr4 1 0.30 0.37 0.38
132 INT260747 Binding of TLR4 and Tlr2 1 0.05 0.44 0.38
133 INT215275 Tlr4 Positive_regulation of Gene_expression of Ros1 1 0.01 1.37 0.38
134 INT339511 Binding of Tlr4 and Traf6 1 0.05 0.12 0.38
135 INT339512 Negative_regulation of Binding of Tlr4 and Traf6 1 0.05 0.17 0.38
136 INT188560 Negative_regulation of Binding of IRF6 and TLR4 1 0.04 0.58 0.38
137 INT204905 Tlr4 Positive_regulation of gr 1 0.18 0.9 0.38
138 INT324821 Tlr4 Positive_regulation of Gene_expression of Maob 1 0.07 0.44 0.37
139 INT324813 Tlr4 Positive_regulation of Gene_expression of Bad 1 0.02 0.44 0.37
140 INT100091 Tlr4 Regulation of Localization of Tnf 1 0.01 0.42 0.37
141 INT324823 Tlr4 Positive_regulation of Gene_expression of Hmgb1 1 0.21 0.51 0.37
142 INT324818 Hmgb1 Positive_regulation of Gene_expression of Tlr4 1 0.21 0.51 0.37
143 INT178218 IFNA1 Regulation of Tlr7 1 0.04 0.87 0.37
144 INT110135 Tlr4 Regulation of Localization of Gnrh1 1 0.01 0.2 0.36
145 INT324808 Tlr4 Positive_regulation of Bad 1 0.02 0.43 0.36
146 INT337304 PTAFR Positive_regulation of Gene_expression of TLR4 1 0.62 1.99 0.36
147 INT188563 TLR4 Positive_regulation of Gene_expression of PRF1 1 0.03 0.78 0.36
148 INT174699 Binding of Tlr2 and Tlr3 3 0.14 0.66 0.35
149 INT118743 Tlr4 Positive_regulation of Itgam 1 0.39 0.41 0.35
150 INT110132 Tlr4 Regulation of Localization of LH 1 0.01 0.2 0.35
151 INT310765 Binding of Pam and Tlr2 1 0.01 0.57 0.35
152 INT244324 Csf2 Positive_regulation of Tlr4 1 0.23 0.95 0.34
153 INT288200 Tlr2 Positive_regulation of Pik3r1 1 0.05 0.24 0.33
154 INT110134 Tlr4 Regulation of Regulation of Gnrh1 1 0.01 0.15 0.33
155 INT224691 Positive_regulation of Tlr4 Positive_regulation of Gene_expression of Il15 1 0.01 0.66 0.33
156 INT224681 Tlr2 Positive_regulation of Gene_expression of Il15 1 0.01 0.66 0.33
157 INT185385 Binding of TLR2 and TLR4 3 0.27 3.63 0.32
158 INT253766 Binding of Apex1 and Tlr4 1 0.03 0.53 0.32
159 INT295198 Tlr4 Positive_regulation of Gene_expression of Ptger2 1 0.01 0.15 0.32
160 INT322016 Binding of IL1B and TLR4 1 0.05 0.18 0.32
161 INT222441 Tlr4 Positive_regulation of Gene_expression of Tac1 1 0.00 0.39 0.32
162 INT137160 TLR7 Positive_regulation of Gene_expression of CXCR3 1 0.35 0.34 0.32
163 INT276604 Tlr4 Positive_regulation of Gene_expression of Paf 1 0.22 0.37 0.31
164 INT276605 Tlr4 Positive_regulation of Gene_expression of Mthfd1 1 0.06 0.37 0.31
165 INT288198 Binding of Tlr4 and Mapk14 1 0.01 0.63 0.31
166 INT185319 Il6 Positive_regulation of Gene_expression of Tlr4 1 0.11 0.36 0.31
167 INT185322 TNF Positive_regulation of Gene_expression of Tlr4 1 0.01 0.36 0.31
168 INT330383 Binding of TLR2 and TLR3 1 0.07 2.77 0.31
169 INT165921 Tlr4 Positive_regulation of Akt1 1 0.16 0.75 0.31
170 INT330378 Positive_regulation of Binding of TLR2 and TLR3 1 0.10 2.78 0.31
171 INT165920 Negative_regulation of Tlr4 Positive_regulation of Akt1 1 0.13 0.75 0.31
172 INT306323 Tlr4 Positive_regulation of Ticam1 3 0.25 0.55 0.3
173 INT324832 Tlr4 Positive_regulation of IFNA1 1 0.05 0.46 0.3
174 INT229600 Tlr4 Positive_regulation of Il1a 1 0.00 0.41 0.3
175 INT223752 Tlr4 Positive_regulation of Il1 1 0.12 0.64 0.3
176 INT178342 Positive_regulation of Tlr4 Positive_regulation of Il6 1 0.13 0.25 0.3
177 INT306319 Cd14 Positive_regulation of Tlr4 1 0.48 0.29 0.3
178 INT168616 Tlr4 Negative_regulation of Localization of Tnf 1 0.33 0.44 0.3
179 INT137159 Binding of TLR7 and TLR9 1 0.27 0.33 0.29
180 INT137169 Binding of TLR5 and TLR7 1 0.25 0.33 0.29
181 INT354368 FGFR1 Positive_regulation of Tlr4 1 0.01 0.16 0.29
182 INT144862 Tlr4 Positive_regulation of PGE 2 0.13 0.35 0.28
183 INT215274 Tlr4 Positive_regulation of Ros1 2 0.02 1.48 0.28
184 INT310696 Tlr4 Positive_regulation of Positive_regulation of Cftr 1 0.16 0.74 0.28
185 INT337293 PTAFR Positive_regulation of Positive_regulation of TLR4 1 0.62 1.43 0.28
186 INT339494 Eif2ak2 Positive_regulation of Tlr4 1 0.13 0.18 0.28
187 INT310255 Tlr4 Positive_regulation of Gene_expression of Cd86 2 0.18 0.06 0.27
188 INT276953 Positive_regulation of Tlr2 Positive_regulation of Phosphorylation of Stat3 1 0.38 0.93 0.27
189 INT343832 Positive_regulation of EDA Positive_regulation of TLR4 1 0.11 0.43 0.27
190 INT276979 Positive_regulation of Tlr2 Positive_regulation of Gene_expression of Stat3 1 0.38 0.93 0.27
191 INT295197 Tlr4 Positive_regulation of Ptger2 1 0.01 0.05 0.27
192 INT306018 Binding of Tlr4 and Tlr9 1 0.15 0.92 0.27
193 INT222428 Negative_regulation of Tlr4 Positive_regulation of Il6 1 0.01 0.26 0.27
194 INT288497 Binding of Tlr7 and Tlr9 1 0.21 0.97 0.27
195 INT222412 Cd14 Negative_regulation of Binding of Tlr4 1 0.02 0.26 0.27
196 INT137167 Binding of IFNG and TLR3 1 0.24 0.32 0.27
197 INT222440 Tlr4 Positive_regulation of Localization of Pomc 1 0.01 0.35 0.27
198 INT268766 Tlr4 Positive_regulation of Gene_expression of Ccr1 1 0.04 0.4 0.26
199 INT78067 Tlr4 Positive_regulation of Localization of Ptger2 1 0.01 0.07 0.26
200 INT296794 Positive_regulation of Tlr2 Positive_regulation of Pik3r1 1 0.10 1.02 0.26

Single Events

The table below shows the top 100 pain related interactions that have been reported for microglial cell activation involved in immune response. They are ordered first by their pain relevance and then by number of times they were reported in microglial cell activation involved in immune response. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT7533 Gene_expression of Tlr4 720 0.78 343.22 121.57
2 INT1951 Positive_regulation of Tlr4 345 0.70 176.99 62.42
3 INT117223 Gene_expression of TLR4 348 0.78 206.18 54.42
4 INT81289 Positive_regulation of Gene_expression of Tlr4 192 0.69 104.5 33.89
5 INT56809 Binding of Tlr4 184 0.48 106.02 31.18
6 INT118734 Gene_expression of Tlr4 70 0.78 55.7 28.19
7 INT134651 Binding of TLR4 89 0.48 66.96 23.19
8 INT142594 Gene_expression of Tlr2 165 0.78 139.73 22.26
9 INT78057 Localization of Tlr4 140 0.77 67.75 21.72
10 INT7535 Negative_regulation of Tlr4 111 0.56 56.84 21.37
11 INT117220 Positive_regulation of TLR4 64 0.69 53.61 17.33
12 INT52358 Gene_expression of Cx3cr1 25 0.78 18.48 16.65
13 INT43906 Regulation of Tlr4 71 0.53 35.18 15.49
14 INT67641 Negative_regulation of Gene_expression of Tlr4 90 0.58 46 14.6
15 INT151120 Negative_regulation of Tlr4 18 0.59 21.09 14.46
16 INT142593 Positive_regulation of Tlr2 85 0.70 75.9 13.62
17 INT117222 Positive_regulation of Gene_expression of TLR4 80 0.70 51.6 12.9
18 INT149985 Gene_expression of Tlr9 32 0.75 29.83 11.86
19 INT118742 Positive_regulation of Tlr4 32 0.69 27.55 11.09
20 INT157466 Gene_expression of CX3CR1 14 0.76 20.6 10.76
21 INT146991 Positive_regulation of Gene_expression of Tlr4 21 0.69 20.76 8.69
22 INT168642 Gene_expression of Cx3cr1 15 0.77 21.73 8.1
23 INT1952 Negative_regulation of Positive_regulation of Tlr4 33 0.51 15.8 7.41
24 INT1950 Positive_regulation of Positive_regulation of Tlr4 38 0.49 20.17 7.14
25 INT295467 Negative_regulation of Gene_expression of Tlr4 11 0.58 7.94 6.83
26 INT142596 Positive_regulation of Gene_expression of Tlr2 42 0.69 38.41 6.67
27 INT157465 Positive_regulation of Gene_expression of CX3CR1 5 0.49 8.9 6.62
28 INT207892 Binding of Tlr9 35 0.46 26.66 6.61
29 INT97797 Localization of TLR4 18 0.77 13.78 6
30 INT103760 Regulation of Gene_expression of Tlr4 35 0.59 16.26 5.95
31 INT143158 Negative_regulation of Gene_expression of TLR4 31 0.56 20.62 5.69
32 INT168279 Regulation of Tlr4 17 0.54 8.97 5.5
33 INT142595 Negative_regulation of Tlr2 24 0.52 19.17 5.43
34 INT174688 Binding of Tlr2 45 0.42 36.65 5.25
35 INT145767 Negative_regulation of TLR4 18 0.43 11.03 5.25
36 INT145756 Gene_expression of Tlr2 23 0.74 20.77 5.18
37 INT157622 Positive_regulation of Localization of Tlr4 34 0.48 22.63 5.09
38 INT183681 Positive_regulation of Tlr3 20 0.62 16.25 4.54
39 INT188672 Positive_regulation of Tlr9 15 0.67 13.1 4.48
40 INT137178 Gene_expression of TLR3 46 0.72 24.97 4.33
41 INT149986 Positive_regulation of Gene_expression of Tlr9 5 0.67 8.18 4.15
42 INT158595 Gene_expression of Tlr3 25 0.69 12.09 4.07
43 INT186808 Transcription of TLR4 22 0.69 12.77 3.73
44 INT158596 Binding of Tlr3 24 0.47 11.66 3.69
45 INT168639 Positive_regulation of Cx3cr1 7 0.57 8.57 3.67
46 INT143159 Regulation of Gene_expression of TLR4 28 0.62 15.08 3.54
47 INT178711 Protein_catabolism of Tlr4 15 0.84 6.75 3.19
48 INT128305 Positive_regulation of Cx3cr1 4 0.60 2.29 3.04
49 INT145768 Regulation of TLR4 19 0.45 8.31 2.96
50 INT185315 Transcription of Tlr4 24 0.69 8.65 2.93
51 INT260424 Negative_regulation of Tlr9 8 0.41 8.19 2.92
52 INT168636 Regulation of Cx3cr1 2 0.45 4.22 2.87
53 INT157461 Binding of CX3CR1 3 0.36 6.72 2.67
54 INT140164 Positive_regulation of Gene_expression of Cx3cr1 3 0.70 2.78 2.65
55 INT100086 Negative_regulation of Localization of Tlr4 15 0.37 5.92 2.47
56 INT168637 Negative_regulation of Cx3cr1 6 0.58 11.67 2.41
57 INT219180 Gene_expression of TLR7 13 0.68 9.51 2.21
58 INT168638 Positive_regulation of Gene_expression of Cx3cr1 6 0.65 5.15 2.19
59 INT204775 Regulation of Tlr2 21 0.41 13.6 2.18
60 INT222609 Binding of Tlr4 8 0.43 4.03 1.98
61 INT326816 Negative_regulation of Positive_regulation of Tlr4 2 0.59 3.96 1.95
62 INT157464 Positive_regulation of CX3CR1 2 0.68 2.97 1.92
63 INT222903 Gene_expression of TLR1 20 0.60 8.77 1.9
64 INT188678 Binding of Tlr7 14 0.32 6.6 1.89
65 INT295469 Localization of Tlr4 3 0.75 2.22 1.88
66 INT121160 Localization of Cx3cr1 1 0.70 2.06 1.81
67 INT178188 Positive_regulation of Tlr7 12 0.40 6.33 1.77
68 INT301954 Regulation of Negative_regulation of Tlr4 1 0.45 2.46 1.77
69 INT191862 Phosphorylation of Tlr4 17 0.79 6.89 1.74
70 INT228195 Negative_regulation of Gene_expression of Tlr2 14 0.40 12.17 1.74
71 INT188584 Positive_regulation of Positive_regulation of TLR4 8 0.65 5.98 1.64
72 INT174689 Gene_expression of Tlr7 11 0.67 8.24 1.56
73 INT174683 Transcription of Tlr2 12 0.58 5.95 1.4
74 INT96739 Transcription of Cx3cr1 1 0.34 1.34 1.38
75 INT186810 Positive_regulation of TLR3 13 0.65 6.37 1.37
76 INT150730 Regulation of Tlr3 2 0.45 6.51 1.37
77 INT157462 Negative_regulation of Binding of CX3CR1 1 0.42 1.62 1.36
78 INT219159 Positive_regulation of TLR7 8 0.55 2.37 1.32
79 INT204766 Gene_expression of Nod2 4 0.75 4.14 1.3
80 INT221131 Localization of Tlr2 17 0.80 13.82 1.28
81 INT179497 Positive_regulation of Binding of Tlr4 12 0.50 6.49 1.27
82 INT151567 Gene_expression of Tlr9 6 0.72 3.63 1.26
83 INT190804 Positive_regulation of Tlr2 6 0.66 3.7 1.16
84 INT150729 Negative_regulation of Tlr3 3 0.43 3.26 1.14
85 INT152225 Regulation of Positive_regulation of Tlr4 8 0.53 2.5 1.12
86 INT186807 Positive_regulation of Gene_expression of TLR3 8 0.53 7.19 1.08
87 INT288489 Transcription of Tlr3 1 0.51 3.85 1.05
88 INT118738 Transcription of Tlr4 4 0.70 1.39 1
89 INT288483 Gene_expression of Tlr3 8 0.72 4.51 0.97
90 INT120599 Binding of Tlr7 2 0.27 2.16 0.96
91 INT288493 Positive_regulation of Gene_expression of Tlr2 4 0.66 4.38 0.94
92 INT145760 Binding of Tlr2 5 0.46 3.59 0.89
93 INT295466 Positive_regulation of Regulation of Tlr4 2 0.44 1.33 0.89
94 INT168278 Positive_regulation of Phosphorylation of Tlr4 1 0.48 1.05 0.88
95 INT140163 Negative_regulation of Cx3cr1 1 0.59 0.6 0.88
96 INT168277 Phosphorylation of Tlr4 1 0.78 1.05 0.88
97 INT128307 Regulation of Cx3cr1 2 0.44 0.78 0.87
98 INT208243 Positive_regulation of Phosphorylation of Tlr4 5 0.31 3.74 0.86
99 INT186804 Binding of TLR3 14 0.45 8.41 0.79
100 INT188582 Positive_regulation of Transcription of TLR4 2 0.50 4.07 0.77
101 INT280014 Binding of TLR7 4 0.14 3.52 0.76
102 INT288495 Gene_expression of Tlr7 3 0.50 2.83 0.76
103 INT295465 Regulation of Positive_regulation of Tlr4 2 0.39 1.28 0.75
104 INT151128 Positive_regulation of Negative_regulation of Tlr4 2 0.46 1 0.75
105 INT224630 Positive_regulation of Positive_regulation of Tlr2 6 0.46 4.14 0.73
106 INT164780 Phosphorylation of Cx3cr1 1 0.26 0.92 0.73
107 INT164781 Regulation of Gene_expression of Cx3cr1 1 0.26 0.92 0.73
108 INT254115 Negative_regulation of Phosphorylation of Tlr4 5 0.27 3.91 0.71
109 INT228188 Regulation of Gene_expression of Tlr2 5 0.45 6.96 0.71
110 INT331594 Localization of Tlr9 1 0.41 1.66 0.71
111 INT331595 Positive_regulation of Localization of Tlr9 1 0.28 1.66 0.71
112 INT255974 Transcription of Tlr3 10 0.49 6.11 0.7
113 INT186798 Regulation of TLR3 5 0.42 3.13 0.69
114 INT161529 Regulation of Gene_expression of Tlr4 3 0.45 2.7 0.69
115 INT186800 Positive_regulation of Binding of TLR4 2 0.47 1.31 0.67
116 INT236785 Regulation of Positive_regulation of TLR4 1 0.32 1.28 0.66
117 INT296782 Phosphorylation of Tlr9 1 0.61 0.53 0.63
118 INT204525 Negative_regulation of Gene_expression of TLR3 2 0.54 1.8 0.61
119 INT288485 Regulation of Transcription of Tlr3 1 0.20 0.85 0.61
120 INT246423 Negative_regulation of TLR3 1 0.40 2.2 0.6
121 INT178202 Regulation of Tlr7 2 0.34 1.69 0.59
122 INT254177 Positive_regulation of Positive_regulation of Tlr3 3 0.41 2.06 0.58
123 INT236786 Positive_regulation of Localization of TLR4 2 0.45 1.89 0.57
124 INT204864 Negative_regulation of Negative_regulation of Tlr4 3 0.30 2.05 0.56
125 INT183685 Positive_regulation of Gene_expression of Tlr3 4 0.61 1.5 0.53
126 INT260425 Positive_regulation of Gene_expression of Tlr7 3 0.39 2.88 0.53
127 INT252305 Localization of Cx3cr1 3 0.74 1 0.53
128 INT234597 Negative_regulation of Positive_regulation of Tlr2 2 0.30 2.25 0.52
129 INT234587 Positive_regulation of Transcription of Tlr2 3 0.36 1.84 0.51
130 INT288490 Binding of Tlr9 1 0.25 1.88 0.51
131 INT285448 Positive_regulation of Gene_expression of TLR7 4 0.61 2.58 0.5
132 INT245223 Negative_regulation of Gene_expression of TLR7 3 0.37 2.81 0.5
133 INT246926 Negative_regulation of Transcription of Tlr4 3 0.41 1.78 0.49
134 INT188677 Positive_regulation of Positive_regulation of Tlr9 2 0.29 1.22 0.49
135 INT242887 Positive_regulation of Gene_expression of TLR1 2 0.28 1.87 0.49
136 INT343888 Regulation of Regulation of TLR4 1 0.25 1.34 0.49
137 INT140167 Binding of Cx3cr1 2 0.48 0.4 0.48
138 INT147606 Positive_regulation of TLR1 5 0.67 4.35 0.47
139 INT202063 Regulation of Binding of TLR4 2 0.44 2.14 0.47
140 INT182237 Transcription of CX3CR1 1 0.59 0.46 0.47
141 INT204781 Positive_regulation of Nod2 6 0.45 2.79 0.46
142 INT152229 Positive_regulation of Regulation of Tlr4 2 0.40 0.29 0.46
143 INT260427 Negative_regulation of Tlr7 2 0.33 1.42 0.42
144 INT237905 Positive_regulation of Binding of Tlr3 1 0.30 0.79 0.42
145 INT178171 Localization of Tlr7 1 0.51 0.53 0.41
146 INT183680 Localization of Tlr3 6 0.71 1.69 0.39
147 INT185313 Regulation of Transcription of Tlr4 3 0.20 0.49 0.39
148 INT181027 Binding of Cx3cr1 1 0.04 1.08 0.39
149 INT219182 Negative_regulation of Positive_regulation of TLR7 1 0.24 1.3 0.39
150 INT230469 Binding of TLR1 6 0.40 1.81 0.38
151 INT178182 Negative_regulation of Binding of Tlr4 3 0.33 2.13 0.38
152 INT284455 Regulation of Gene_expression of Tlr9 1 0.30 1.19 0.37
153 INT174684 Gene_expression of Tlr6 2 0.44 2.62 0.36
154 INT118736 Positive_regulation of Transcription of Tlr4 1 0.49 0.42 0.35
155 INT242895 Negative_regulation of Gene_expression of TLR1 3 0.38 0.95 0.34
156 INT246419 Positive_regulation of Negative_regulation of TLR3 1 0.43 0.67 0.34
157 INT230494 Regulation of Binding of Tlr4 3 0.45 2.97 0.31
158 INT329061 Positive_regulation of Tlr9 1 0.47 2.05 0.29
159 INT288189 Negative_regulation of Negative_regulation of Tlr2 1 0.26 0.43 0.28
160 INT331590 Negative_regulation of Binding of Tlr9 1 0.24 1.52 0.28
161 INT346895 Positive_regulation of Gene_expression of Nod2 1 0.33 0.74 0.28
162 INT236357 Negative_regulation of Positive_regulation of Tlr9 2 0.33 3.1 0.27
163 INT157768 Negative_regulation of Binding of TLR4 1 0.43 0.29 0.27
164 INT242891 Transcription of TLR1 5 0.56 0.86 0.26
165 INT288186 Regulation of Binding of Tlr2 2 0.32 1.72 0.26
166 INT224614 Regulation of Positive_regulation of Tlr2 1 0.13 0.56 0.26
167 INT346896 Binding of Nod2 1 0.21 0.72 0.26
168 INT204866 Regulation of Localization of Tlr4 3 0.37 0.66 0.25
169 INT219175 Localization of TLR7 2 0.49 1.32 0.25
170 INT145758 Regulation of Tlr2 3 0.43 0.94 0.23
171 INT145761 Negative_regulation of Tlr2 2 0.41 1.97 0.23
172 INT215080 Positive_regulation of Negative_regulation of Tlr4 1 0.31 0.05 0.23
173 INT301950 Regulation of Regulation of Tlr4 1 0.40 0.32 0.23
174 INT346899 Regulation of Positive_regulation of Nod2 1 0.18 0.75 0.22
175 INT348772 Positive_regulation of Positive_regulation of Tlr4 1 0.61 0.72 0.21
176 INT245220 Regulation of TLR1 1 0.36 1.6 0.21
177 INT186803 Transcription of TLR3 6 0.67 1.54 0.2
178 INT245222 Regulation of TLR7 2 0.39 1.52 0.19
179 INT254194 Regulation of Positive_regulation of Tlr3 2 0.52 0.79 0.19
180 INT233472 Positive_regulation of Positive_regulation of Cx3cr1 1 0.41 0.32 0.19
181 INT288491 Positive_regulation of Transcription of Tlr3 1 0.37 1.85 0.19
182 INT334246 Positive_regulation of Protein_catabolism of Tlr4 1 0.07 0.18 0.18
183 INT324855 Binding of Tlr6 1 0.14 2.39 0.17
184 INT306008 Positive_regulation of Transcription of Tlr4 2 0.50 1.41 0.16
185 INT294633 Positive_regulation of Binding of Tlr2 1 0.44 0.42 0.16
186 INT336418 Negative_regulation of Binding of Tlr3 1 0.36 0.59 0.16
187 INT145759 Regulation of Gene_expression of Tlr2 3 0.43 0.98 0.14
188 INT285435 Protein_catabolism of TLR4 2 0.62 0.9 0.14
189 INT246424 Negative_regulation of Transcription of TLR4 2 0.41 0.52 0.14
190 INT290324 Positive_regulation of Binding of TLR1 1 0.22 0.48 0.14
191 INT290321 Negative_regulation of Positive_regulation of TLR1 1 0.19 0.48 0.14
192 INT285444 Localization of TLR1 2 0.63 0.47 0.13
193 INT301958 Positive_regulation of Regulation of Tlr2 1 0.21 0.32 0.13
194 INT285441 Regulation of Localization of TLR4 2 0.38 0.15 0.12
195 INT186797 Localization of TLR3 2 0.70 2.69 0.12
196 INT120600 Positive_regulation of Binding of Tlr7 1 0.04 0.17 0.12
197 INT260428 Regulation of Gene_expression of Tlr7 1 0.25 1.01 0.12
198 INT151569 Transcription of Tlr9 3 0.69 0.75 0.11
199 INT186809 Positive_regulation of Transcription of TLR3 2 0.65 0.5 0.11
200 INT151566 Positive_regulation of Transcription of Tlr9 2 0.47 0.67 0.11
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