GO:0002318

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Name myeloid progenitor cell differentiation
Categary Process
Go Slim No
Go Link GO:0002318
Unique Molecular Interactions 106
Total Molecular Interactions 143
Total Single Events 1544
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for myeloid progenitor cell differentiation. They are ordered first by their pain relevance and then by number of times they were reported for myeloid progenitor cell differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT298283 Pou4f1 Positive_regulation of Gene_expression of Runx1 1 0.50 1.4 1.48
2 INT99577 Binding of KITLG and Kit 3 0.34 2.33 1.11
3 INT298272 Runx1 Positive_regulation of Gene_expression of Ntrk3 1 0.52 0.88 1.09
4 INT298298 Calca Negative_regulation of Gene_expression of Runx1 1 0.19 0.33 1
5 INT298274 Gene_expression of Runx1 Negative_regulation of Calca 1 0.19 0.33 1
6 INT41617 Sp5 Positive_regulation of Mlf1 1 0.02 0.25 0.94
7 INT326455 Runx1 Positive_regulation of Gene_expression of Trpv1 1 0.45 0 0.88
8 INT298289 Runx1 Negative_regulation of Ntrk2 1 0.60 1.09 0.87
9 INT298295 Runx1 Negative_regulation of Gene_expression of Ntrk1 2 0.38 0.45 0.86
10 INT99578 Binding of CEL and Kit 1 0.04 1.07 0.81
11 INT151453 Gtf3a Regulation of Kit 1 0.04 0.25 0.78
12 INT210144 Binding of Slc6a3 and Slc37a4 1 0.11 0.23 0.72
13 INT326457 Runx1 Regulation of Mrgpra3 1 0.37 0.1 0.71
14 INT326456 Runx1 Regulation of Pip4k2b 1 0.09 0.11 0.71
15 INT108018 Binding of Slc37a4 and Clec4d 1 0.00 1.18 0.6
16 INT280895 Runx1 Positive_regulation of Gene_expression of Ret 2 0.33 0.2 0.58
17 INT298278 Runx1 Negative_regulation of Gene_expression of Ntrk2 1 0.44 0.8 0.56
18 INT245553 Runx1 Positive_regulation of Gene_expression of Ntrk1 2 0.45 1.41 0.52
19 INT237154 LGALS4 Positive_regulation of KIT 1 0.10 1.99 0.47
20 INT326458 Runx1 Negative_regulation of Gene_expression of Calca 1 0.18 0.05 0.43
21 INT298287 Runx1 Negative_regulation of Gene_expression of Ntrk3 1 0.32 0.4 0.43
22 INT298286 Runx3 Regulation of Gene_expression of Runx1 1 0.47 0.36 0.41
23 INT327727 Atp6v0a2 Negative_regulation of Gene_expression of Kit 1 0.05 0.83 0.41
24 INT298270 Gene_expression of Runx1 Positive_regulation of Ntrk3 1 0.35 0.34 0.4
25 INT298261 Pou4f1 Negative_regulation of Gene_expression of Runx1 1 0.45 0.58 0.4
26 INT298296 Gene_expression of Runx1 Negative_regulation of Gene_expression of Ntrk2 1 0.44 0.33 0.39
27 INT298266 Gene_expression of Runx1 Positive_regulation of Ntrk1 1 0.28 0.34 0.39
28 INT148246 Binding of KITLG and Positive_regulation of Kit 1 0.04 0.43 0.38
29 INT148247 KITLG Positive_regulation of Kit 1 0.03 0.43 0.38
30 INT148243 Binding of Akt1 and Kit 1 0.03 0.44 0.35
31 INT148240 Binding of Kit and Ret 1 0.24 0.44 0.35
32 INT148241 Binding of Kit and Ntrk1 1 0.25 0.44 0.35
33 INT235872 Phosphorylation of Ppp2ca Positive_regulation of Slc37a4 1 0.00 0.15 0.31
34 INT148242 Binding of Kit and Gtf3a 1 0.04 0.34 0.3
35 INT235886 Ppp2ca Positive_regulation of Slc37a4 1 0.00 0.15 0.3
36 INT298282 Pou4f1 Regulation of Gene_expression of Runx1 1 0.48 0.36 0.29
37 INT245563 Negative_regulation of Runx1 Regulation of Ret 1 0.39 0.76 0.29
38 INT245556 Runx1 Regulation of Ret 1 0.56 0.76 0.29
39 INT258343 Binding of Aicda and Kit 1 0.06 0.57 0.26
40 INT245557 Runx1 Positive_regulation of Gene_expression of Tbx15 1 0.02 0.75 0.25
41 INT245561 Gene_expression of Runx1 Positive_regulation of Gene_expression of Tbx15 1 0.02 0.8 0.25
42 INT245555 Runx1 Negative_regulation of Cdkn1a 1 0.29 1.17 0.23
43 INT245565 Runx1 Negative_regulation of Negative_regulation of Cdkn1a 1 0.29 1.17 0.23
44 INT237201 Cd3e Positive_regulation of KIT 1 0.03 0 0.21
45 INT282852 Binding of Slc37a4 and Slc5a8 1 0.01 0.77 0.21
46 INT282851 Binding of Slc37a4 and Sema6a 1 0.00 0.55 0.21
47 INT305533 Runx1 Positive_regulation of Il3 1 0.03 0.28 0.19
48 INT249962 Binding of KIT and KITLG 6 0.19 3.69 0.17
49 INT298293 Runx1 Positive_regulation of Negative_regulation of Ntrk2 1 0.52 0.54 0.16
50 INT245568 Runx1 Regulation of Gtf3a 1 0.00 0.65 0.16
51 INT298256 Runx1 Positive_regulation of Negative_regulation of Ntrk1 1 0.30 0.55 0.16
52 INT245559 Runx3 Regulation of Runx1 1 0.31 0.63 0.16
53 INT245566 Runx1 Negative_regulation of Ntrk1 1 0.39 0.65 0.15
54 INT213800 Kit Positive_regulation of Mitf 1 0.30 1.24 0.15
55 INT245552 Runx1 Negative_regulation of Calca 1 0.33 0.65 0.15
56 INT139538 Binding of CD34 and KIT 2 0.39 2.73 0.14
57 INT302826 Negative_regulation of Binding of Il2 and Kit 1 0.01 1.28 0.14
58 INT302827 Binding of Il2 and Kit 1 0.01 1.27 0.14
59 INT213797 Kit Positive_regulation of Tfe3 1 0.28 1.24 0.14
60 INT280893 Gene_expression of Runx1 Positive_regulation of Gene_expression of Ntrk1 1 0.33 0.44 0.1
61 INT298267 Tcf3 Positive_regulation of Gene_expression of Runx1 1 0.21 0.6 0.1
62 INT245570 Runx1 Regulation of Regulation of BDNF 1 0.26 0.28 0.1
63 INT305535 Binding of HPRT1 and Runx1 1 0.41 0.7 0.1
64 INT244640 AGK Negative_regulation of KIT 1 0.00 0.69 0.08
65 INT280894 Runx1 Positive_regulation of Transcription of Ntrk1 1 0.38 0.36 0.07
66 INT237197 KIT Positive_regulation of LPT 1 0.00 0.15 0.06
67 INT292089 Binding of KIT and TXK 1 0.02 1.54 0.04
68 INT292084 Binding of FLT3 and TXK 1 0.02 1.53 0.04
69 INT292090 Negative_regulation of Binding of KIT and TXK 1 0.02 1.54 0.04
70 INT270825 P2rx7 Positive_regulation of Slc37a4 1 0.01 0 0.04
71 INT292085 Negative_regulation of Binding of FLT3 and TXK 1 0.02 1.54 0.04
72 INT337727 ADAMTS2 Positive_regulation of Gene_expression of KIT 1 0.02 0 0.03
73 INT201620 Binding of Kit and Uvbi1 1 0.03 0.2 0
74 INT234612 Binding of KIT and STIP1 1 0.04 1 0
75 INT241500 Binding of Kit and Kitl 1 0.08 0.92 0
76 INT186999 Binding of KIT and Gtf3a 1 0.00 0.25 0
77 INT217136 Negative_regulation of MIR221 Negative_regulation of Gene_expression of KIT 1 0.18 0.74 0
78 INT310191 Flt3 Positive_regulation of Gene_expression of Id1 1 0.03 0.81 0
79 INT192956 Binding of CD2 and KIT 1 0.03 0.62 0
80 INT211572 Binding of Kit and Pik3r1 1 0.21 0.06 0
81 INT301245 Binding of FUT1 and Runx1 1 0.00 0.66 0
82 INT136516 PLAT Regulation of MLF1 1 0.02 0 0
83 INT315856 FLT3 Positive_regulation of Gene_expression of PDGFA 1 0.01 1.15 0
84 INT192955 Binding of KIT and VCAM1 1 0.05 0.63 0
85 INT211570 Kit Regulation of Gene_expression of Lpin1 1 0.27 0.12 0
86 INT301241 Mir29a Positive_regulation of Runx1 1 0.00 2.85 0
87 INT282743 Hsp90aa1 Positive_regulation of Kit 1 0.22 0.54 0
88 INT347035 Binding of Kit and Cd34 1 0.02 1.38 0
89 INT211574 Regulation of Binding of Kit and Pik3r1 1 0.16 0.06 0
90 INT280546 Binding of KIT and TP63 1 0.01 1.19 0
91 INT350722 Binding of Runx1 and Negative_regulation of Gene_expression of MIR17 1 0.01 0.22 0
92 INT217138 Negative_regulation of MIR222 Negative_regulation of Gene_expression of KIT 1 0.16 0.74 0
93 INT237153 LGALS4 Regulation of KIT 1 0.09 0 0
94 INT201612 Binding of Kit and Mc1r 1 0.34 0.13 0
95 INT150180 KIT Negative_regulation of Gene_expression of HLA-B 1 0.39 0.09 0
96 INT301238 Gene_expression of Mir29a Positive_regulation of Runx1 1 0.00 1.39 0
97 INT337732 KITLG Positive_regulation of KIT 1 0.03 0 0
98 INT295426 Binding of KIT and PDGFRB 1 0.24 0.4 0
99 INT301235 Binding of Runx1 and Mir29a 1 0.00 0.48 0
100 INT312379 KIT Positive_regulation of Positive_regulation of Kit 1 0.01 1.37 0
101 INT337731 Binding of KIT and ADAMTS2 1 0.01 0.12 0
102 INT211571 Pik3r1 Positive_regulation of Gene_expression of Kit 1 0.30 0.3 0
103 INT211882 Binding of KIT and CDCP1 1 0.00 2.1 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for myeloid progenitor cell differentiation. They are ordered first by their pain relevance and then by number of times they were reported in myeloid progenitor cell differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT133211 Gene_expression of Runx1 169 0.77 83.4 76.16
2 INT91891 Gene_expression of Kit 268 0.78 158.89 22.67
3 INT245517 Positive_regulation of Gene_expression of Runx1 49 0.69 17.7 12.38
4 INT107033 Gene_expression of Slc37a4 66 0.62 27.34 12.35
5 INT133212 Negative_regulation of Runx1 21 0.58 11.16 11.89
6 INT133210 Positive_regulation of Runx1 33 0.69 18.25 10.12
7 INT245538 Negative_regulation of Gene_expression of Runx1 20 0.58 11.68 9.97
8 INT69264 Gene_expression of KIT 207 0.78 179.41 8.95
9 INT82709 Negative_regulation of Slc37a4 17 0.34 3.41 8.6
10 INT169596 Transcription of Runx1 12 0.71 5.55 6.27
11 INT245515 Regulation of Runx1 14 0.61 5.07 6.22
12 INT245536 Regulation of Gene_expression of Runx1 11 0.58 6.22 4.88
13 INT88278 Binding of Kit 33 0.37 24.45 4.13
14 INT124185 Negative_regulation of Kit 57 0.59 35.43 3.61
15 INT91890 Positive_regulation of Kit 36 0.50 25.44 3.06
16 INT169553 Positive_regulation of Slc37a4 9 0.13 2.94 2.49
17 INT151449 Negative_regulation of Gene_expression of Kit 18 0.45 12.05 2.23
18 INT85085 Positive_regulation of KIT 36 0.53 30.08 2.17
19 INT109327 Negative_regulation of KIT 42 0.57 43.2 2.15
20 INT86460 Binding of Slc37a4 5 0.04 1.8 2.08
21 INT169597 Negative_regulation of Transcription of Runx1 3 0.58 1.92 2.07
22 INT99572 Localization of Kit 13 0.75 5.23 1.95
23 INT245529 Binding of Runx1 9 0.48 4.42 1.9
24 INT140175 Regulation of Kit 23 0.62 8.59 1.79
25 INT305526 Negative_regulation of Positive_regulation of Runx1 1 0.42 2.7 1.65
26 INT151450 Positive_regulation of Gene_expression of Kit 23 0.69 13.11 1.43
27 INT245530 Localization of Runx1 2 0.80 1.55 1.17
28 INT326445 Negative_regulation of Negative_regulation of Runx1 1 0.43 0.77 1.06
29 INT232636 Positive_regulation of Binding of Kit 4 0.39 1.98 0.98
30 INT205902 Regulation of Gene_expression of Slc37a4 1 0.09 0.4 0.93
31 INT41616 Positive_regulation of Mlf1 1 0.33 0.24 0.92
32 INT298252 Regulation of Localization of Runx1 1 0.43 0.85 0.88
33 INT150108 Positive_regulation of Gene_expression of Slc37a4 5 0.35 2.09 0.83
34 INT305528 Regulation of Binding of Runx1 1 0.27 1.06 0.77
35 INT189438 Regulation of Gene_expression of Kit 10 0.45 4.94 0.61
36 INT204254 Localization of KIT 8 0.73 6.78 0.61
37 INT129783 Positive_regulation of Gene_expression of KIT 16 0.50 18.12 0.58
38 INT86461 Positive_regulation of Binding of Slc37a4 1 0.02 0.57 0.51
39 INT128376 Binding of KIT 26 0.48 14.24 0.47
40 INT186998 Negative_regulation of Gene_expression of KIT 20 0.43 16.77 0.46
41 INT213789 Phosphorylation of Kit 7 0.69 5.32 0.43
42 INT150103 Negative_regulation of Gene_expression of Slc37a4 3 0.32 0.81 0.41
43 INT151963 Negative_regulation of Positive_regulation of Kit 1 0.37 0.31 0.4
44 INT305525 Positive_regulation of Positive_regulation of Runx1 1 0.46 0.76 0.39
45 INT109329 Negative_regulation of FLT3 7 0.29 6.88 0.38
46 INT23520 Binding of MLF1 1 0.18 0 0.38
47 INT109328 Gene_expression of FLT3 6 0.61 4.78 0.37
48 INT175710 Regulation of Slc37a4 2 0.26 1.03 0.35
49 INT309528 Gene_expression of MLF1 1 0.09 0 0.34
50 INT155426 Gene_expression of Kit 3 0.49 2.71 0.31
51 INT245547 Positive_regulation of Localization of Runx1 1 0.50 0.73 0.31
52 INT136517 Regulation of MLF1 3 0.06 0.1 0.27
53 INT213777 Positive_regulation of Phosphorylation of Kit 2 0.58 1.36 0.26
54 INT124944 Regulation of KIT 15 0.60 11.84 0.24
55 INT234614 Phosphorylation of KIT 6 0.78 4.85 0.23
56 INT192957 Transcription of KIT 5 0.69 2.19 0.23
57 INT237188 Negative_regulation of Localization of KIT 1 0.08 0 0.22
58 INT245526 Regulation of Transcription of Runx1 1 0.27 0.92 0.21
59 INT199555 Negative_regulation of Flt3 5 0.33 3.64 0.16
60 INT111546 Negative_regulation of Phosphorylation of FLT3 1 0.06 0.77 0.15
61 INT111548 Phosphorylation of FLT3 1 0.12 0.77 0.15
62 INT136519 Positive_regulation of MLF1 2 0.06 0 0.14
63 INT309529 Positive_regulation of Positive_regulation of MLF1 1 0.06 0 0.11
64 INT309532 Negative_regulation of Gene_expression of MLF1 1 0.05 0 0.11
65 INT309531 Regulation of Gene_expression of MLF1 1 0.05 0 0.11
66 INT326104 Binding of Kit 1 0.30 0.39 0.1
67 INT199124 Transcription of Kit 6 0.67 1.49 0.09
68 INT229573 Positive_regulation of Positive_regulation of Kit 3 0.39 1.46 0.09
69 INT81383 Binding of FLT3 2 0.36 0.31 0.09
70 INT295429 Positive_regulation of Phosphorylation of KIT 1 0.42 0.84 0.07
71 INT163458 Negative_regulation of Regulation of Kit 2 0.12 1.61 0.06
72 INT200837 Negative_regulation of Binding of Kit 2 0.23 0.94 0.06
73 INT179325 Negative_regulation of Regulation of KIT 1 0.43 0.82 0.04
74 INT295428 Negative_regulation of Binding of KIT 1 0.36 1.01 0.04
75 INT292125 Negative_regulation of Gene_expression of FLT3 1 0.06 1.39 0.04
76 INT234613 Positive_regulation of Positive_regulation of KIT 1 0.49 2.41 0.04
77 INT241510 Negative_regulation of Phosphorylation of Kit 3 0.31 2.06 0.03
78 INT251796 Regulation of FLT3 2 0.35 3.11 0.03
79 INT284182 Gene_expression of Flt3 2 0.41 0.43 0.03
80 INT284961 Protein_catabolism of FLT3 1 0.01 0.58 0.03
81 INT192960 Regulation of Gene_expression of KIT 3 0.45 4.16 0
82 INT199558 Regulation of Flt3 2 0.09 1.52 0
83 INT211563 Regulation of Negative_regulation of Kit 1 0.45 0.19 0
84 INT282736 Protein_catabolism of Kit 1 0.55 0.54 0
85 INT123391 Negative_regulation of Positive_regulation of FLT3 1 0.06 0.71 0
86 INT192962 Positive_regulation of Transcription of KIT 1 0.46 2.74 0
87 INT217234 Negative_regulation of Transcription of KIT 1 0.24 0.57 0
88 INT232629 Positive_regulation of Localization of Kit 1 0.44 0.8 0
89 INT254318 Localization of Slc37a4 1 0.01 2.2 0
90 INT292123 Positive_regulation of Negative_regulation of KIT 1 0.10 1.08 0
91 INT234615 Regulation of Positive_regulation of KIT 1 0.44 1.38 0
92 INT315983 Localization of Flt3 1 0.42 0.21 0
93 INT123392 Positive_regulation of FLT3 1 0.10 0.7 0
94 INT232632 Regulation of Localization of Kit 1 0.40 0.81 0
95 INT211533 Regulation of Regulation of Kit 1 0.62 0.24 0
96 INT315866 Localization of FLT3 1 0.21 1.02 0
97 INT282731 Positive_regulation of Protein_catabolism of Kit 1 0.39 0.54 0
98 INT312378 Positive_regulation of Kit 1 0.04 1.36 0
99 INT175469 Phosphorylation of Slc37a4 1 0.06 1.54 0
100 INT305522 Positive_regulation of Negative_regulation of Runx1 1 0.50 0.15 0
101 INT337747 Positive_regulation of Localization of KIT 1 0.32 0 0
102 INT309530 Negative_regulation of MLF1 1 0.05 0.05 0
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