GO:0002352

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Name B cell negative selection
Categary Process
Go Slim No
Go Link GO:0002352
Unique Molecular Interactions 108
Total Molecular Interactions 131
Total Single Events 1120
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for B cell negative selection. They are ordered first by their pain relevance and then by number of times they were reported for B cell negative selection. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT296793 Akt1 Positive_regulation of Gene_expression of Bax 1 0.11 0.75 0.65
2 INT296790 Tlr9 Regulation of Bax 1 0.14 0.76 0.65
3 INT296791 Positive_regulation of Akt1 Positive_regulation of Gene_expression of Bax 1 0.11 0.8 0.65
4 INT112699 Bid Regulation of Bax 1 0.25 0.51 0.61
5 INT41174 Bak1 Regulation of Localization of Prl 1 0.02 0 0.46
6 INT238638 Gopc Negative_regulation of Gene_expression of Bax 1 0.04 0.85 0.45
7 INT155061 Stat3 Negative_regulation of Bax 1 0.22 3.71 0.34
8 INT155063 Csf2 Negative_regulation of Gene_expression of Bax 1 0.27 1.46 0.18
9 INT285026 Bak1 Regulation of Bcl2 1 0.09 0.71 0.17
10 INT285022 Regulation of Bak1 Regulation of Bcl2 1 0.09 0.71 0.17
11 INT155066 Csf2 Negative_regulation of Bax 1 0.12 1.89 0.17
12 INT349475 Regulation of Bax Regulation of Bcl2 1 0.07 1.35 0.17
13 INT285024 Bcl2 Regulation of Bak1 1 0.09 0.71 0.17
14 INT336891 Epo Negative_regulation of Transcription of Bax 1 0.10 0.68 0.16
15 INT349476 Bax Regulation of Bcl2 1 0.07 1.33 0.15
16 INT273040 Vip Regulation of Bax 1 0.23 1.69 0.13
17 INT273041 Adcyap1 Regulation of Bax 1 0.21 1.69 0.13
18 INT226192 Protein_catabolism of Bax Positive_regulation of Gtf3a 1 0.00 0.53 0.12
19 INT285030 Binding of Bax and Slc25a4 1 0.03 0.84 0.11
20 INT204300 Bcl2 Negative_regulation of Positive_regulation of Bak1 1 0.02 1.13 0.09
21 INT302290 Birc5 Regulation of BAK1 1 0.21 1.22 0.07
22 INT204301 Positive_regulation of Hrk Positive_regulation of Positive_regulation of Bak1 1 0.00 1.17 0.07
23 INT302131 Negative_regulation of SOD2 Regulation of BAK1 1 0.09 1.22 0.07
24 INT302289 Negative_regulation of Birc5 Regulation of BAK1 1 0.20 1.22 0.07
25 INT285025 Bnip3 Positive_regulation of Bak1 1 0.11 0.78 0.07
26 INT285032 Bnip3 Positive_regulation of Bax 1 0.28 0.77 0.07
27 INT340401 Positive_regulation of Bax Positive_regulation of Binding of Hrk 1 0.01 0.79 0.07
28 INT302128 SOD2 Regulation of BAK1 1 0.09 1.22 0.07
29 INT340395 Binding of Bax and Tg(CAG-EGFP)D4Nagy 1 0.02 0.43 0.07
30 INT302147 PTGER2 Positive_regulation of BAK1 1 0.06 2.08 0.06
31 INT302138 PTGER2 Positive_regulation of Gene_expression of BAK1 1 0.06 2.08 0.06
32 INT340394 Binding of Bax and Bbc3 1 0.01 0.36 0.04
33 INT204298 Bid Positive_regulation of Binding of Bak1 1 0.05 0.57 0.04
34 INT172902 Binding of Bax and Bcl2 5 0.30 3.19 0.03
35 INT192164 Binding of BAK1 and BCL2 3 0.04 2.8 0.03
36 INT192167 Negative_regulation of Binding of BAK1 and BCL2 2 0.05 1.89 0.03
37 INT192165 Binding of BAK1 and BCL2L1 2 0.06 1.35 0.03
38 INT192166 Negative_regulation of Binding of BAK1 and BCL2L1 1 0.05 1.06 0.03
39 INT297737 Cbr1 Positive_regulation of Bax 1 0.06 0.53 0.03
40 INT224682 Mcl1 Regulation of Bak1 1 0.01 1.09 0.03
41 INT333259 Bcl2 Regulation of Bax 1 0.03 0.32 0.03
42 INT224689 Binding of Bak1 and Mcl1 1 0.01 1.09 0.03
43 INT224676 Binding of Bax and Mcl1 1 0.01 1.09 0.03
44 INT333249 Cxcl12 Positive_regulation of Positive_regulation of Bak1 1 0.30 0.32 0.03
45 INT224690 Mcl1 Regulation of Bax 1 0.00 1.09 0.03
46 INT333262 Bcl2 Regulation of Bak1 1 0.04 0.31 0.03
47 INT341376 Sod2 Regulation of Bax 1 0.09 0.99 0.03
48 INT283013 Binding of Bak1 and Bcl2 4 0.06 1.03 0
49 INT185852 Binding of BAK1 and BAX 3 0.29 2.5 0
50 INT172906 Binding of Bax and Bcl2l1 2 0.16 2.03 0
51 INT185851 BID Positive_regulation of BAK1 1 0.43 0.73 0
52 INT285029 Binding of Bax and Bcl2l1 1 0.25 0.1 0
53 INT330047 Binding of Bax and Bcl2l11 1 0.13 0.62 0
54 INT191058 Binding of Bcl2 and Positive_regulation of Gene_expression of Bax 1 0.21 0.49 0
55 INT333258 Gene_expression of Cxcl12 Positive_regulation of Positive_regulation of Bak1 1 0.15 0.55 0
56 INT254707 Positive_regulation of Map2k1 Regulation of Gene_expression of BAK1 1 0.05 0.67 0
57 INT322658 Binding of Bak1 and Prdm8 1 0.02 0.89 0
58 INT242483 Negative_regulation of Ciapin1 Negative_regulation of Positive_regulation of Bax 1 0.17 1.76 0
59 INT136914 Mapk8 Positive_regulation of Localization of Bax 1 0.51 0.12 0
60 INT302137 Binding of BAD and BAK1 1 0.07 0.93 0
61 INT322664 Prdm8 Positive_regulation of Gene_expression of Bax 1 0.01 1.1 0
62 INT285028 Binding of Bcl2 and Bax 1 0.32 0.1 0
63 INT229821 Fos Positive_regulation of Bax 1 0.15 0.27 0
64 INT322668 Prdm8 Positive_regulation of Gene_expression of Bak1 1 0.02 1.1 0
65 INT309517 Binding of Bax and Xrcc6 1 0.15 0.5 0
66 INT201761 BIK Positive_regulation of Positive_regulation of Bax 1 0.01 0.43 0
67 INT330052 Binding of Bax and Bid 1 0.15 0.62 0
68 INT322662 Binding of Bax and Pbrm1 1 0.08 0.9 0
69 INT172908 Binding of Bad and Bax 1 0.01 1.34 0
70 INT330057 Bid Positive_regulation of Bax 1 0.19 0.62 0
71 INT283002 Binding of Bak1 and Mgst1 1 0.01 0.24 0
72 INT313426 Positive_regulation of Ppp2ca Positive_regulation of Bax 1 0.46 0.36 0
73 INT267252 Bax Regulation of Bak1 1 0.05 1.09 0
74 INT259049 Binding of BAK1 and HPV18I1 1 0.00 1.19 0
75 INT201765 Binding of BCL2L1 and Bax 1 0.00 0.28 0
76 INT352151 Binding of Bak1 and Gopc 1 0.02 0.26 0
77 INT201763 BID Positive_regulation of Positive_regulation of Bax 1 0.01 0.43 0
78 INT242476 Negative_regulation of Ciapin1 Positive_regulation of Bax 1 0.19 1.29 0
79 INT322670 Prdm8 Positive_regulation of Bax 1 0.01 1.1 0
80 INT275753 xn Regulation of Bax 1 0.05 1.31 0
81 INT333681 Trp53 Regulation of Negative_regulation of Bax 1 0.15 1.17 0
82 INT334718 Binding of NOS1 and Bax 1 0.02 0.87 0
83 INT330054 Bcl2l11 Positive_regulation of Bax 1 0.25 0.62 0
84 INT322666 Binding of Bak1 and Pbrm1 1 0.20 0.9 0
85 INT254090 EPO Negative_regulation of Gene_expression of Bax 1 0.10 0.63 0
86 INT340400 Binding of Bax and Mom6 1 0.04 0.28 0
87 INT275746 Binding of xn and Bax 1 0.05 2.57 0
88 INT322663 Prdm8 Positive_regulation of Bak1 1 0.01 1.1 0
89 INT340399 Binding of Bak1 and Bax 1 0.12 0.91 0
90 INT309518 Negative_regulation of Binding of Bax and Xrcc6 1 0.16 0.25 0
91 INT201768 BCL2L11 Positive_regulation of Positive_regulation of Bax 1 0.00 0.43 0
92 INT198023 Binding of BAK1 and BID 1 0.12 0.82 0
93 INT198015 Binding of BAK1 and MCL1 1 0.26 5.16 0
94 INT201743 Bad Positive_regulation of Positive_regulation of Bax 1 0.00 0.43 0
95 INT302132 Negative_regulation of Binding of BAD and BAK1 1 0.06 0.93 0
96 INT136915 RYBP Positive_regulation of Localization of Bax 1 0.01 0.12 0
97 INT322660 Binding of Bax and Prdm8 1 0.01 0.89 0
98 INT100425 Bax Regulation of Pcbd1 1 0.06 0.06 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for B cell negative selection. They are ordered first by their pain relevance and then by number of times they were reported in B cell negative selection. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT100423 Gene_expression of Bax 141 0.75 98.43 24.48
2 INT109511 Gene_expression of Bax 133 0.78 113.22 14.36
3 INT102110 Positive_regulation of Gene_expression of Bax 42 0.67 35.77 9.51
4 INT102106 Positive_regulation of Bax 48 0.67 30.62 9.28
5 INT80037 Gene_expression of BAK1 58 0.75 39.49 9.08
6 INT102107 Negative_regulation of Gene_expression of Bax 30 0.57 29.48 7.33
7 INT98837 Positive_regulation of Bax 72 0.61 63.14 6.41
8 INT145929 Regulation of Bax 20 0.60 18.12 5.35
9 INT109513 Positive_regulation of Gene_expression of Bax 37 0.67 29.52 5.06
10 INT99504 Negative_regulation of Bax 19 0.56 8.89 4.44
11 INT103345 Positive_regulation of Gene_expression of BAK1 10 0.57 6.4 4.19
12 INT123752 Regulation of Bax 19 0.60 16.45 4
13 INT112692 Localization of Bax 31 0.80 20.97 3.98
14 INT74293 Positive_regulation of BAK1 13 0.60 14.13 2.73
15 INT102146 Phosphorylation of Bax 4 0.66 3.48 2.35
16 INT154970 Localization of Bax 15 0.74 11.12 2.11
17 INT98836 Transcription of Bax 6 0.69 5.04 1.96
18 INT134442 Transcription of Bax 14 0.67 7.6 1.9
19 INT135540 Negative_regulation of Bax 16 0.48 11.8 1.89
20 INT134443 Binding of Bax 10 0.47 5.62 1.84
21 INT104883 Positive_regulation of Positive_regulation of Bax 4 0.45 4.05 1.74
22 INT103967 Negative_regulation of Gene_expression of BAK1 8 0.42 7.02 1.54
23 INT62800 Regulation of BAK1 7 0.41 10.12 1.47
24 INT146785 Positive_regulation of Localization of Bax 7 0.69 6.16 1.47
25 INT109512 Negative_regulation of Gene_expression of Bax 12 0.42 8.04 1.44
26 INT112695 Negative_regulation of Protein_catabolism of Bax 3 0.36 1.72 1.3
27 INT142017 Positive_regulation of Positive_regulation of BAK1 2 0.52 1.74 1.3
28 INT154969 Positive_regulation of Localization of Bax 4 0.64 3.42 1.27
29 INT112693 Protein_catabolism of Bax 5 0.74 3.17 1.2
30 INT141189 Negative_regulation of Transcription of Bax 1 0.41 1.42 1.14
31 INT93094 Gene_expression of Bak1 13 0.52 13.94 1.02
32 INT175507 Regulation of Gene_expression of Bax 13 0.50 10.91 0.95
33 INT135542 Positive_regulation of Bak1 17 0.43 16.12 0.88
34 INT144697 Regulation of Gene_expression of Bax 8 0.37 9.5 0.81
35 INT14040 Binding of Bak1 2 0.30 0.55 0.72
36 INT14041 Regulation of Binding of Bak1 1 0.23 0 0.68
37 INT204290 Positive_regulation of Bak1 3 0.22 5.19 0.66
38 INT285007 Regulation of Bak1 1 0.20 3.46 0.56
39 INT176242 Binding of Bax 10 0.42 10.18 0.52
40 INT135541 Negative_regulation of Bak1 6 0.30 4.52 0.49
41 INT102108 Protein_catabolism of Bax 8 0.64 5.69 0.48
42 INT134446 Positive_regulation of Binding of Bax 1 0.49 0.72 0.48
43 INT152059 Regulation of Transcription of Bax 1 0.26 0.07 0.42
44 INT150946 Negative_regulation of Positive_regulation of Bak1 2 0.29 3.02 0.4
45 INT135802 Positive_regulation of Negative_regulation of Bax 2 0.41 0.57 0.4
46 INT204069 Negative_regulation of Positive_regulation of Bax 5 0.31 3.08 0.34
47 INT169538 Negative_regulation of Localization of Bax 3 0.49 1.41 0.34
48 INT184482 Positive_regulation of Positive_regulation of Bax 5 0.41 4.7 0.33
49 INT172216 Binding of Bak1 5 0.25 8.48 0.33
50 INT221191 Negative_regulation of Localization of Bax 4 0.38 2.85 0.33
51 INT93093 Regulation of Gene_expression of Bak1 3 0.30 2.09 0.32
52 INT122950 Binding of BAK1 16 0.41 12.85 0.31
53 INT140379 Positive_regulation of Gene_expression of Bak1 4 0.27 2.27 0.31
54 INT229853 Gene_expression of Bak1 2 0.25 2.04 0.29
55 INT102111 Positive_regulation of Protein_catabolism of Bax 2 0.45 1.14 0.27
56 INT150947 Positive_regulation of Positive_regulation of Bak1 1 0.05 0.6 0.25
57 INT135543 Negative_regulation of Positive_regulation of Bax 5 0.30 6.4 0.23
58 INT187555 Transcription of BAK1 3 0.19 2.6 0.21
59 INT187556 Regulation of Transcription of BAK1 1 0.02 1.22 0.21
60 INT282088 Localization of Bak1 6 0.54 3.78 0.19
61 INT300463 Regulation of Regulation of Bax 1 0.29 1.33 0.18
62 INT198036 Negative_regulation of BAK1 5 0.27 5.98 0.17
63 INT320315 Protein_catabolism of BAK1 3 0.76 3.13 0.13
64 INT285005 Negative_regulation of Bak1 1 0.14 0.16 0.13
65 INT185872 Localization of BAK1 6 0.74 11.28 0.12
66 INT265485 Positive_regulation of Localization of BAK1 4 0.50 5.17 0.12
67 INT185907 Positive_regulation of Binding of BAK1 2 0.60 1.59 0.12
68 INT238490 Regulation of Regulation of BAK1 1 0.19 2.56 0.12
69 INT336888 Negative_regulation of Transcription of Bax 1 0.07 0.68 0.11
70 INT304137 Regulation of Localization of Bax 2 0.24 1.7 0.09
71 INT327140 Regulation of Localization of BAK1 1 0.45 0.71 0.07
72 INT285012 Positive_regulation of Positive_regulation of Bak1 1 0.16 0.77 0.07
73 INT322649 Positive_regulation of Localization of Bak1 1 0.47 1.04 0.07
74 INT307466 Positive_regulation of Phosphorylation of Bax 1 0.15 0.76 0.07
75 INT285008 Negative_regulation of Regulation of Bak1 1 0.14 0.87 0.07
76 INT333214 Regulation of Bak1 1 0.18 1.1 0.06
77 INT268304 Negative_regulation of Gene_expression of Bak1 3 0.28 1.95 0.05
78 INT268622 Regulation of Negative_regulation of Bax 1 0.12 0.81 0.05
79 INT309494 Negative_regulation of Binding of Bax 2 0.38 1.31 0.04
80 INT340387 Regulation of Positive_regulation of Bax 1 0.27 0.61 0.04
81 INT340390 Regulation of Binding of Bax 1 0.54 0.59 0.04
82 INT123525 Phosphorylation of Bax 3 0.41 1.18 0.03
83 INT176247 Positive_regulation of Phosphorylation of Bax 1 0.12 0.42 0.03
84 INT254700 Regulation of Gene_expression of BAK1 4 0.39 1.36 0
85 INT330041 Positive_regulation of Regulation of Bax 1 0.29 1.63 0
86 INT333213 Regulation of Transcription of Bax 1 0.11 0.14 0
87 INT333223 Phosphorylation of Bak1 1 0.32 0.69 0
88 INT333207 Regulation of Transcription of Bak1 1 0.18 0.15 0
89 INT333212 Transcription of Bak1 1 0.27 0.15 0
90 INT322640 Positive_regulation of Binding of Bax 1 0.12 0.88 0
91 INT234056 Positive_regulation of Transcription of Bax 1 0.35 0.36 0
92 INT302235 Regulation of Binding of BAK1 1 0.19 1.15 0
93 INT285015 Transcription of Bak1 1 0.22 0.09 0
94 INT285001 Positive_regulation of Transcription of Bak1 1 0.16 0.09 0
95 INT280154 Positive_regulation of Regulation of BAK1 1 0.04 0.68 0
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