GO:0002353

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Name plasma kallikrein-kinin cascade
Categary Process
Go Slim No
Go Link GO:0002353
Unique Molecular Interactions 11
Total Molecular Interactions 16
Total Single Events 117
Pain Genes Associated 2

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for plasma kallikrein-kinin cascade. They are ordered first by their pain relevance and then by number of times they were reported for plasma kallikrein-kinin cascade. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT327090 Negative_regulation of F12 Negative_regulation of Gene_expression of KNG1 1 0.00 0.51 0.45
2 INT119717 Binding of ADRA1D and F12 1 0.35 0.23 0.23
3 INT332700 Binding of F12 and KNG1 1 0.15 1.05 0.21
4 INT250550 Binding of F12 and CHDH 1 0.05 2.26 0.17
5 INT232015 SERPING1 Negative_regulation of F12 2 0.24 1.19 0.12
6 INT232017 F12 Positive_regulation of PLG 1 0.03 0.52 0.11
7 INT232019 F12 Positive_regulation of TRGC1 1 0.00 0.57 0.09
8 INT310201 Binding of F12 and Chdh 1 0.04 1.06 0.08
9 INT232009 Positive_regulation of F12 Negative_regulation of Localization of KNG1 1 0.01 0.19 0.05
10 INT327162 Binding of SERPING1 and F12 1 0.05 0.29 0.04
11 INT310200 Binding of Serping1 and F12 1 0.21 0.05 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for plasma kallikrein-kinin cascade. They are ordered first by their pain relevance and then by number of times they were reported in plasma kallikrein-kinin cascade. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT27465 Positive_regulation of F12 21 0.70 8.09 3.06
2 INT11481 Positive_regulation of F12 11 0.58 5.53 1.8
3 INT77164 Binding of F12 8 0.47 2.66 1.48
4 INT11496 Negative_regulation of F12 6 0.59 3.41 1.27
5 INT10133 Negative_regulation of F12 16 0.49 5.21 1.26
6 INT27155 Binding of F12 8 0.36 1.61 1.21
7 INT44001 Negative_regulation of Positive_regulation of F12 5 0.59 2.53 0.73
8 INT90699 Regulation of F12 4 0.45 2.7 0.67
9 INT221932 Gene_expression of F12 4 0.66 2.61 0.5
10 INT10129 Gene_expression of F12 4 0.65 3.4 0.37
11 INT77162 Regulation of Binding of F12 2 0.33 0.52 0.28
12 INT77165 Regulation of Positive_regulation of F12 1 0.38 0.28 0.23
13 INT77160 Positive_regulation of Binding of F12 1 0.42 0.28 0.23
14 INT77156 Regulation of Binding of F12 1 0.13 0.25 0.23
15 INT77153 Positive_regulation of Binding of F12 1 0.14 0.26 0.22
16 INT119715 Localization of F12 3 0.67 1.24 0.17
17 INT58589 Regulation of F12 3 0.39 1.9 0.16
18 INT96541 Negative_regulation of Binding of F12 2 0.41 0.32 0.16
19 INT119714 Protein_catabolism of F12 1 0.84 0.14 0.14
20 INT10128 Negative_regulation of Gene_expression of F12 2 0.01 0.33 0.12
21 INT316316 Negative_regulation of Binding of F12 1 0.18 1.1 0.12
22 INT232026 Positive_regulation of Gene_expression of F12 1 0.03 0.58 0.11
23 INT310198 Positive_regulation of Positive_regulation of F12 1 0.38 1.63 0.09
24 INT123574 Localization of F12 1 0.15 0.25 0.09
25 INT326466 Regulation of Gene_expression of F12 1 0.03 0.6 0
26 INT326467 Regulation of Gene_expression of F12 1 0.44 0.6 0
27 INT250579 Transcription of F12 1 0.62 0.77 0
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