GO:0002430

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Name complement receptor mediated signaling pathway
Categary Process
Go Slim No
Go Link GO:0002430
Unique Molecular Interactions 31
Total Molecular Interactions 39
Total Single Events 228
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for complement receptor mediated signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported for complement receptor mediated signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT152504 Binding of CR1 and Tnf 1 0.00 0.49 1.04
2 INT316889 Binding of Cd19 and Cr2 1 0.07 1.7 0.61
3 INT316882 Binding of Cd22 and Cr2 1 0.02 1.71 0.61
4 INT125699 CR1 Negative_regulation of Positive_regulation of ABCA1 1 0.03 0.64 0.53
5 INT258338 Binding of Aicda and Cr2 1 0.24 1.35 0.51
6 INT148611 Binding of CD8A and Cr2 1 0.02 0.81 0.44
7 INT203140 Binding of C5ar1 and C5 1 0.39 0.81 0.38
8 INT316884 Positive_regulation of Binding of Cr2 and Bcr 1 0.06 0.86 0.31
9 INT316886 Positive_regulation of Binding of Cd22 and Cr2 1 0.02 0.86 0.31
10 INT316885 Binding of Cr2 and Bcr 1 0.06 0.85 0.3
11 INT289406 C3ar1 Positive_regulation of Gene_expression of Il12a 1 0.01 1.04 0.25
12 INT322018 CR1 Negative_regulation of IL1B 1 0.00 0.17 0.25
13 INT20392 FPR1 Positive_regulation of CR1 1 0.04 0.22 0.22
14 INT332013 Hc Regulation of Binding of C3ar1 1 0.12 1.11 0.21
15 INT332016 C3ar1 Regulation of Binding of Hc 1 0.12 1.11 0.21
16 INT181082 Binding of C3 and C3ar1 1 0.03 1.31 0.19
17 INT258342 Scara3 Positive_regulation of Cr2 1 0.05 0.52 0.12
18 INT289405 Mthfd1 Positive_regulation of C3ar1 1 0.00 0.53 0.11
19 INT332019 Binding of C3ar1 and Cfb 1 0.03 0.29 0.09
20 INT20393 Negative_regulation of FPR1 Positive_regulation of CR1 1 0.03 0.07 0.07
21 INT322013 Negative_regulation of CR1 Negative_regulation of IL1B 1 0.00 0 0.06
22 INT256990 Binding of Cd81 and Cr2 1 0.18 0.36 0.05
23 INT245219 Binding of C3AR1 and C5AR1 1 0.34 1.21 0.04
24 INT245216 Binding of C3 and C3AR1 1 0.19 1.21 0.04
25 INT321004 C5AR1 Regulation of C3ar1 1 0.01 0 0.03
26 INT316354 Binding of CR1 and Gypa 1 0.05 0.43 0
27 INT316355 Binding of CR1 and Hmgcr 1 0.01 0.59 0
28 INT218513 Binding of C3AR1 and ap 1 0.00 0.36 0
29 INT256991 Binding of Cr2 and Cd19 1 0.05 0.18 0
30 INT279501 C3ar1 Positive_regulation of C3 1 0.01 0 0
31 INT229930 C3AR1 Positive_regulation of C3 1 0.00 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for complement receptor mediated signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported in complement receptor mediated signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT167052 Gene_expression of Cr2 43 0.56 25.7 7.76
2 INT22916 Negative_regulation of CR1 12 0.57 6.31 2.42
3 INT183360 Binding of Cr2 13 0.27 7.68 2.19
4 INT181015 Gene_expression of C3ar1 12 0.58 8.9 2.18
5 INT9261 Gene_expression of CR1 15 0.73 15.58 1.85
6 INT216512 Gene_expression of C3AR1 13 0.70 8.44 1.31
7 INT152503 Binding of CR1 3 0.45 8.64 1.03
8 INT184352 Positive_regulation of Cr2 6 0.42 2.81 0.96
9 INT184376 Negative_regulation of Cr2 3 0.36 2.28 0.89
10 INT20401 Positive_regulation of CR1 10 0.49 3.77 0.87
11 INT258307 Positive_regulation of Gene_expression of Cr2 1 0.36 1.72 0.69
12 INT216510 Binding of C3AR1 2 0.06 1.59 0.67
13 INT38720 Protein_catabolism of C3AR1 2 0.17 0.18 0.62
14 INT220272 Negative_regulation of Gene_expression of C3ar1 1 0.03 1.11 0.56
15 INT247586 Localization of Cr2 3 0.54 3.09 0.47
16 INT20402 Negative_regulation of Positive_regulation of CR1 1 0.18 0.47 0.46
17 INT220894 Positive_regulation of C3ar1 4 0.09 3.75 0.41
18 INT332001 Binding of C3ar1 1 0.28 2.15 0.39
19 INT228771 Localization of C3ar1 2 0.03 2.71 0.38
20 INT203145 Binding of C5ar1 1 0.35 0.81 0.38
21 INT258309 Negative_regulation of Binding of Cr2 2 0.30 1.58 0.36
22 INT53157 Regulation of Cr2 2 0.15 2.32 0.33
23 INT320993 Regulation of C3ar1 2 0.18 1.11 0.3
24 INT258324 Regulation of Gene_expression of Cr2 1 0.32 0.51 0.3
25 INT332007 Negative_regulation of C3ar1 1 0.39 1.99 0.3
26 INT258305 Negative_regulation of Gene_expression of Cr2 1 0.30 0.51 0.29
27 INT180536 Positive_regulation of Gene_expression of CR1 1 0.45 1.13 0.28
28 INT97897 Regulation of CR1 2 0.22 0.51 0.26
29 INT258327 Regulation of Binding of Cr2 1 0.28 0.51 0.26
30 INT66121 Negative_regulation of C5ar1 1 0.09 0 0.17
31 INT258325 Positive_regulation of Localization of Cr2 1 0.36 0.35 0.14
32 INT258304 Transcription of Cr2 1 0.43 0.39 0.13
33 INT234050 Positive_regulation of Gene_expression of C3ar1 1 0.06 0.46 0.07
34 INT218484 Regulation of Gene_expression of C3AR1 1 0.01 0.22 0.05
35 INT229965 Localization of C3AR1 1 0.01 0.25 0.04
36 INT191729 Negative_regulation of Gene_expression of CR1 2 0.40 2.26 0
37 INT229964 Positive_regulation of C3AR1 1 0.02 0.82 0
38 INT316345 Negative_regulation of Binding of CR1 1 0.40 0.23 0
39 INT113264 Regulation of Gene_expression of CR1 1 0.34 0.1 0
40 INT354843 Protein_catabolism of CR1 1 0.22 1.67 0
41 INT316350 Regulation of Positive_regulation of CR1 1 0.42 0.49 0
42 INT316346 Localization of CR1 1 0.70 1.47 0
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