GO:0002438

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Name acute inflammatory response to antigenic stimulus
Categary Process
Go Slim No
Go Link GO:0002438
Unique Molecular Interactions 238
Total Molecular Interactions 313
Total Single Events 2853
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for acute inflammatory response to antigenic stimulus. They are ordered first by their pain relevance and then by number of times they were reported for acute inflammatory response to antigenic stimulus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT18026 Binding of Oprd1 and Oprm1 4 0.40 0.83 3.53
2 INT96461 Pnoc Positive_regulation of Oprm1 1 0.09 0.73 2.34
3 INT134583 Arrb2 Regulation of Oprm1 1 0.41 1.23 2.15
4 INT64750 Binding of Oprm1 and Pck1 2 0.41 0.51 2.07
5 INT107738 Binding of Pld2 and Oprm1 1 0.23 0 1.93
6 INT146587 Npff Negative_regulation of Positive_regulation of Casp3 1 0.05 0.18 1.92
7 INT146586 Npff Negative_regulation of Gene_expression of Casp3 1 0.06 0.18 1.92
8 INT29996 Binding of Oprm1 and Penk 2 0.36 0.4 1.85
9 INT185143 Elane Positive_regulation of Pik3r1 1 0.01 0 1.72
10 INT96296 Oprm1 Negative_regulation of Npr1 2 0.05 0.32 1.65
11 INT109525 Binding of DMRT1 and Oprm1 1 0.08 0 1.62
12 INT72666 Binding of ODT and Oprm1 1 0.03 0.53 1.5
13 INT324926 Ptpro Positive_regulation of Bdkrb2 1 0.01 2.25 1.5
14 INT141673 Oprm1 Positive_regulation of Negative_regulation of Ltp 1 0.13 0 1.46
15 INT141674 Oprm1 Positive_regulation of Ltp 1 0.13 0 1.46
16 INT131039 Binding of Oprm1 and Prf1 1 0.17 0 1.45
17 INT131041 Negative_regulation of Binding of Oprm1 and Prf1 1 0.21 0 1.45
18 INT131040 Binding of Oprm1 and S100a9 1 0.24 0 1.45
19 INT139987 Oprm1 Positive_regulation of Localization of Oprl1 1 0.16 0.17 1.35
20 INT91305 Binding of Npff and Npffr2 2 0.31 0.64 1.32
21 INT128310 Oprm1 Positive_regulation of Oprm1 1 0.00 0.1 1.29
22 INT89943 Binding of Oprm1 and Il2 1 0.03 0.53 1.28
23 INT64749 Negative_regulation of Binding of Oprm1 and Pck1 1 0.47 0.21 1.27
24 INT126801 Regulation of Binding of Oprm1 and Penk 1 0.34 0.4 1.25
25 INT76165 IGKV2-30 Positive_regulation of Phosphorylation of Oprm1 1 0.00 0.08 1.22
26 INT76163 Prkaca Positive_regulation of Phosphorylation of Oprm1 1 0.02 0.08 1.22
27 INT62019 CSF2 Regulation of ELANE 1 0.03 0.47 1.21
28 INT133496 Binding of Oprm1 and Cckbr 1 0.15 0 1.19
29 INT77982 Binding of YY1 and Oprm1 2 0.17 0.17 1.06
30 INT73311 Binding of Oprm1 and Pdpn 1 0.08 0.71 1.06
31 INT312097 ELANE Regulation of ALOX5 1 0.08 1.75 1.05
32 INT145906 Elane Regulation of Transcription of Oprm1 1 0.10 0.14 1.04
33 INT83903 Penk Positive_regulation of Npff 1 0.49 0 1.02
34 INT70105 SCD Positive_regulation of Oprm1 1 0.01 0 1
35 INT94989 Arrb2 Regulation of Regulation of Oprm1 1 0.24 0 0.98
36 INT62017 ELANE Positive_regulation of Localization of ACOT1 1 0.05 0.35 0.98
37 INT57555 Binding of Oprm1 and Oprl1 2 0.06 0.05 0.97
38 INT83415 Binding of Oprm1 and Ntrk1 1 0.01 0 0.96
39 INT13193 FPR1 Positive_regulation of ELANE 3 0.44 1.22 0.92
40 INT79123 Binding of Pnoc and Oprm1 3 0.14 0 0.91
41 INT61046 Oprm1 Positive_regulation of Gh1 1 0.21 0 0.89
42 INT83417 Binding of OPRL1 and Oprm1 1 0.01 0 0.89
43 INT97184 Oprm1 Regulation of Gene_expression of Pomc 1 0.31 0 0.89
44 INT61047 Oprm1 Positive_regulation of Localization of Gh1 1 0.29 0 0.89
45 INT61048 Oprm1 Positive_regulation of Localization of Prl 1 0.16 0 0.88
46 INT61045 Oprm1 Positive_regulation of Prl 1 0.16 0 0.88
47 INT112153 Regulation of Binding of Oprm1 and Rtcd1 1 0.00 0.09 0.87
48 INT63859 Oprm1 Negative_regulation of Oprm1 1 0.10 0.08 0.86
49 INT63858 Oprm1 Negative_regulation of Penk 1 0.05 0.08 0.86
50 INT120999 Binding of Oprm1 and Ifng 1 0.22 0.57 0.84
51 INT32441 POMC Positive_regulation of ELANE 1 0.13 0.09 0.83
52 INT112154 Binding of Oprm1 and Rtcd1 1 0.00 0.09 0.81
53 INT150643 Binding of Bdkrb2 and Trpa1 1 0.36 0.55 0.78
54 INT55923 Penk Regulation of Transcription of Oprm1 1 0.26 0 0.78
55 INT142454 Npff Positive_regulation of Gtpbp4 1 0.56 0 0.78
56 INT55922 Penk Regulation of Oprm1 1 0.26 0 0.78
57 INT142455 Binding of Npff and Gtpbp4 1 0.40 0 0.78
58 INT121647 Binding of Oprm1 and Atrn 1 0.01 0.12 0.77
59 INT140790 Positive_regulation of Ptger3 Negative_regulation of Negative_regulation of Bdkrb2 1 0.00 0.07 0.76
60 INT124404 Binding of POMC and Oprm1 1 0.00 0.25 0.75
61 INT185140 Elane Positive_regulation of Prkca 1 0.00 0 0.74
62 INT312101 ELANE Regulation of ALOX5AP 1 0.21 1.11 0.73
63 INT71595 Camk2a Regulation of Negative_regulation of Oprm1 1 0.04 0 0.69
64 INT293010 ELANE Regulation of Localization of LTF 1 0.00 0.54 0.67
65 INT312105 ELANE Positive_regulation of Localization of PTGER2 4 0.03 1.3 0.64
66 INT160880 Pld2 Positive_regulation of Oprm1 1 0.07 0.08 0.63
67 INT160882 Pld2 Positive_regulation of Gene_expression of Oprm1 1 0.06 0.08 0.63
68 INT252772 ELANE Regulation of Gene_expression of CCL2 1 0.05 2.16 0.62
69 INT121460 KNG1 Positive_regulation of Bdkrb2 1 0.08 0.44 0.62
70 INT121459 Bdkrb2 Positive_regulation of KNG1 1 0.09 0.44 0.62
71 INT32782 Binding of Vip and Elane 1 0.17 0 0.61
72 INT133707 Npff Positive_regulation of Npffr1 1 0.73 0.73 0.61
73 INT6723 Negative_regulation of Pomc Positive_regulation of Positive_regulation of Oprm1 1 0.20 0.55 0.6
74 INT64776 Binding of Oprm1 and Kcnj3 1 0.38 0 0.6
75 INT121453 Bdkrb2 Positive_regulation of Trpv1 1 0.28 0.42 0.6
76 INT91306 Binding of Npff and Npffr1 1 0.23 0.17 0.6
77 INT117707 Oprm1 Positive_regulation of PIK3CG 1 0.00 0.08 0.6
78 INT123009 Oprm1 Positive_regulation of Localization of OR6K2 1 0.00 0 0.59
79 INT50434 Binding of Oprm1 and Mop3 1 0.00 0 0.58
80 INT254637 Bdkrb2 Regulation of Gene_expression of Ccl5 1 0.17 1.22 0.56
81 INT126641 Binding of KNG1 and Bdkrb2 1 0.11 0.42 0.55
82 INT168128 Oprm1 Regulation of Mir190 1 0.11 0 0.54
83 INT57248 ELANE Regulation of Gene_expression of CGA 1 0.05 0 0.52
84 INT90067 Binding of Oprd1 and Npff 1 0.20 0.09 0.52
85 INT303722 KNG1 Positive_regulation of Bdkrb2 1 0.01 0.7 0.52
86 INT126654 Oprd1 Regulation of Oprm1 1 0.03 0.13 0.52
87 INT312118 ELANE Regulation of PTGES 1 0.22 0.92 0.49
88 INT254638 Bdkrb2 Positive_regulation of Positive_regulation of Bdkrb1 1 0.09 0.96 0.48
89 INT31818 Negative_regulation of Binding of Sst and Oprm1 1 0.26 0.3 0.48
90 INT31817 Positive_regulation of Binding of Sst and Oprm1 1 0.30 0.3 0.48
91 INT160881 Positive_regulation of Oprm1 Positive_regulation of Positive_regulation of Pld2 1 0.05 0.08 0.48
92 INT31816 Binding of Sst and Oprm1 1 0.22 0.3 0.48
93 INT83690 Binding of Oprm1 and Ptprg 1 0.00 0.08 0.48
94 INT61848 Npff Regulation of Localization of Avp 1 0.26 0.3 0.48
95 INT80116 Binding of C4orf6 and Bdkrb2 1 0.41 0.18 0.47
96 INT65006 DAK Negative_regulation of ELANE 1 0.05 0.35 0.47
97 INT312112 ELANE Regulation of Transcription of ALOX5 1 0.09 0.82 0.47
98 INT64217 Oprm1 Positive_regulation of Oprd1 1 0.24 0 0.46
99 INT221026 ELANE Positive_regulation of Gene_expression of CCL18 1 0.01 0.57 0.45
100 INT73055 Binding of Oprm1 and Ncr1 1 0.07 0.32 0.45
101 INT56631 Negative_regulation of FPR1 Positive_regulation of ELANE 1 0.38 0.54 0.44
102 INT353331 Elane Positive_regulation of F2r 1 0.08 0.78 0.44
103 INT254636 Bdkrb2 Regulation of Gene_expression of Ccl2 1 0.15 1.15 0.43
104 INT139487 Oprm1 Positive_regulation of Th 1 0.26 0.1 0.42
105 INT33006 Oprm1 Regulation of Localization of LH 1 0.03 0 0.42
106 INT139488 Oprm1 Positive_regulation of Cnr1 1 0.17 0.1 0.42
107 INT139489 Oprm1 Positive_regulation of Penk 1 0.23 0.1 0.42
108 INT293007 IRF6 Positive_regulation of ELANE 1 0.00 0 0.42
109 INT139486 Oprm1 Positive_regulation of Crh 1 0.27 0.1 0.42
110 INT221027 ELANE Positive_regulation of IL8 2 0.14 1.3 0.4
111 INT85511 Binding of KNG1 and Bdkrb2 1 0.54 0.51 0.4
112 INT312123 ELANE Positive_regulation of ALOX5 1 0.09 0.74 0.4
113 INT133708 Npff Negative_regulation of Phosphorylation of Ppp1r1b 1 0.30 0.41 0.4
114 INT312122 ELANE Positive_regulation of Protein_catabolism of COL2A1 1 0.05 0.65 0.39
115 INT312086 ELANE Positive_regulation of MMP13 1 0.13 0.64 0.39
116 INT330120 Bdkrb2 Regulation of Bdkrb1 1 0.19 1.26 0.38
117 INT67287 Negative_regulation of Binding of Oprd1 and Oprm1 1 0.03 0.18 0.37
118 INT163572 Pomc Positive_regulation of Oprm1 1 0.06 0.1 0.37
119 INT21111 Binding of Oprm1 and RGD735065 1 0.02 0 0.37
120 INT93202 Binding of IGHG3 and Oprm1 1 0.02 0 0.35
121 INT7893 Binding of Oprm1 and Ccl21b 1 0.00 0.08 0.35
122 INT312750 Elane Positive_regulation of Positive_regulation of Ltp 1 0.01 0.38 0.34
123 INT90543 Npff Negative_regulation of Regulation of Pnoc 1 0.26 0 0.34
124 INT312119 ELANE Positive_regulation of Gene_expression of PTGES 1 0.18 0.74 0.33
125 INT85909 Binding of Oprm1 and GREM1 1 0.00 0 0.32
126 INT312099 ELANE Positive_regulation of Gene_expression of PTGER2 1 0.02 0.64 0.32
127 INT346286 ELANE Positive_regulation of MAPK1 1 0.06 0.65 0.32
128 INT346281 Binding of ELANE and MAPK1 1 0.04 0.65 0.32
129 INT312085 ELANE Regulation of Regulation of ALOX5 1 0.09 0.64 0.32
130 INT63584 Oprm1 Positive_regulation of Hrasls 1 0.00 0 0.29
131 INT190826 ELANE Positive_regulation of Localization of MUC1 1 0.07 0 0.29
132 INT116358 Binding of C3 and ELANE 1 0.12 0 0.29
133 INT116356 Positive_regulation of Binding of C3 and ELANE 1 0.16 0 0.29
134 INT5935 Por Regulation of Oprm1 1 0.19 0.51 0.28
135 INT5933 Dlst Regulation of Oprm1 1 0.09 0.51 0.28
136 INT5934 Prl Regulation of Oprm1 1 0.19 0.51 0.28
137 INT105877 Positive_regulation of Binding of Ins1 and Oprm1 1 0.21 0.67 0.28
138 INT105872 Binding of Ins1 and Oprm1 1 0.16 0.58 0.27
139 INT18027 Binding of Oprm1 and Prodh2 1 0.00 0 0.26
140 INT149358 Binding of Oprm1 and Positive_regulation of Positive_regulation of Npr1 1 0.00 0.09 0.26
141 INT312115 ELANE Positive_regulation of Transcription of PTGES 1 0.25 0.53 0.25
142 INT312569 IL6 Positive_regulation of Localization of ELANE 1 0.11 1.05 0.24
143 INT81252 Uts2r Regulation of Gene_expression of Oprm1 1 0.01 0.07 0.24
144 INT15829 Ambp Regulation of Positive_regulation of ELANE 1 0.00 0 0.24
145 INT202422 IL8 Positive_regulation of Localization of ELANE 1 0.02 0.91 0.24
146 INT106547 Oprm1 Regulation of Oprm1 1 0.04 0 0.23
147 INT222178 SERPINB1 Regulation of ELANE 1 0.00 1.04 0.23
148 INT147886 Oprm1 Regulation of POMC 1 0.02 0 0.23
149 INT259623 Binding of Eln and Elane 1 0.02 1.38 0.23
150 INT133166 ELANE Regulation of Tnf 1 0.01 0.98 0.22
151 INT107031 Regulation of Binding of Tacr1 and Oprm1 1 0.29 0.5 0.21
152 INT57250 ELANE Positive_regulation of Localization of CGA 1 0.08 0 0.21
153 INT107032 Binding of Tacr1 and Oprm1 1 0.31 0.5 0.21
154 INT310939 Binding of ELANE and COPD 1 0.08 1.51 0.2
155 INT252814 ELANE Positive_regulation of Positive_regulation of CCL2 1 0.05 0.8 0.2
156 INT310938 Binding of ELANE and HRCT1 1 0.02 1.5 0.2
157 INT83869 Oprm1 Regulation of Gene_expression of Fos 1 0.01 0 0.18
158 INT259634 Elane Positive_regulation of Gene_expression of COPD 1 0.01 0.92 0.17
159 INT221025 TNF Positive_regulation of ELANE 1 0.01 0.13 0.17
160 INT346305 Binding of ELANE and Col2a1 1 0.00 0.98 0.17
161 INT312109 ELANE Positive_regulation of EGR1 1 0.15 0.23 0.16
162 INT312100 ELANE Positive_regulation of Binding of EGR1 1 0.16 0.23 0.16
163 INT312111 ELANE Regulation of Transcription of PTGES 1 0.22 0.23 0.16
164 INT116359 Positive_regulation of Binding of C4A and ELANE 1 0.14 0 0.15
165 INT221030 ELANE Positive_regulation of CXCL10 1 0.01 0.24 0.15
166 INT242400 Binding of Bdkrb2 and Ros1 1 0.02 0.84 0.15
167 INT312126 ELANE Positive_regulation of ALOX5AP 1 0.20 0.25 0.15
168 INT22820 ADRA1D Regulation of ELANE 1 0.21 0 0.15
169 INT312092 ELANE Positive_regulation of Gene_expression of EGR1 1 0.19 0.21 0.15
170 INT221035 ELANE Positive_regulation of CCL18 1 0.01 0.24 0.15
171 INT21453 Ambp Regulation of ELANE 1 0.00 0 0.15
172 INT221019 ELANE Positive_regulation of CCL3 1 0.00 0.24 0.15
173 INT116357 Binding of C4A and ELANE 1 0.11 0 0.14
174 INT312096 ELANE Positive_regulation of Transcription of ALOX5 1 0.06 0.27 0.13
175 INT252785 ELANE Regulation of Gene_expression of FBRS 1 0.00 0.5 0.13
176 INT179234 Binding of SERPINA6 and ELANE 1 0.01 0.22 0.12
177 INT312570 AMBP Regulation of Negative_regulation of ELANE 1 0.06 0.95 0.12
178 INT191759 NFASC Negative_regulation of ELANE 1 0.00 0.98 0.11
179 INT312094 ELANE Positive_regulation of PTGES 1 0.29 0.34 0.11
180 INT102587 Npff Positive_regulation of Gene_expression of Nts 1 0.37 0.07 0.1
181 INT324828 ELANE Positive_regulation of Localization of Ecm1 1 0.00 0.61 0.09
182 INT312103 ELANE Regulation of Gene_expression of ALOX5 1 0.06 0.15 0.08
183 INT24660 Positive_regulation of Binding of ELANE and SERPINA1 1 0.17 0.73 0.08
184 INT259622 Elane Positive_regulation of Protein_catabolism of Ecm1 1 0.00 0.38 0.08
185 INT312093 ELANE Regulation of Gene_expression of ALOX5AP 1 0.13 0.15 0.08
186 INT21452 Ambp Regulation of Gene_expression of ELANE 1 0.00 0 0.08
187 INT56377 AMBP Negative_regulation of Elane 1 0.00 1.43 0.08
188 INT24659 Binding of ELANE and SERPINA1 1 0.13 0.73 0.08
189 INT312113 ELANE Positive_regulation of Gene_expression of ALOX5AP 1 0.23 0.14 0.07
190 INT346302 ELANE Regulation of Col2a1 1 0.00 0.3 0.05
191 INT339020 SERPINA1 Negative_regulation of ELANE 1 0.07 0.59 0.05
192 INT312110 ELANE Positive_regulation of Gene_expression of ALOX5 1 0.09 0.07 0.04
193 INT346283 Binding of COL11A1 and ELANE 1 0.01 0.08 0.04
194 INT312117 Negative_regulation of ELANE Positive_regulation of ALOX5AP 1 0.17 0.08 0.04
195 INT179903 Binding of ELANE and SRI 1 0.17 1.07 0.03
196 INT312125 Binding of ELANE and PTGES 1 0.13 0.07 0.03
197 INT252820 ELANE Positive_regulation of Gene_expression of COL1A1 1 0.01 0.58 0
198 INT179904 Positive_regulation of ELANE Positive_regulation of NYS3 1 0.10 0.92 0
199 INT238402 ELANE Positive_regulation of Gene_expression of CDKN1A 1 0.03 0.48 0
200 INT105009 Binding of IFNA1 and Oprm1 1 0.01 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for acute inflammatory response to antigenic stimulus. They are ordered first by their pain relevance and then by number of times they were reported in acute inflammatory response to antigenic stimulus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT6293 Gene_expression of Oprm1 312 0.78 48.73 215.61
2 INT5930 Positive_regulation of Oprm1 221 0.70 31.19 172.93
3 INT6042 Binding of Oprm1 248 0.48 31.77 154.34
4 INT5931 Regulation of Oprm1 149 0.62 18.15 125.93
5 INT5906 Negative_regulation of Oprm1 125 0.59 19.58 101.57
6 INT49747 Transcription of Oprm1 68 0.72 9.01 53.78
7 INT4843 Gene_expression of Npff 50 0.78 12.92 36.37
8 INT14137 Localization of Oprm1 56 0.81 2.88 36.09
9 INT48907 Positive_regulation of Gene_expression of Oprm1 53 0.69 8.55 33.52
10 INT5653 Positive_regulation of ELANE 136 0.70 72.78 27.94
11 INT2609 Localization of ELANE 111 0.81 50.22 26.63
12 INT6294 Regulation of Gene_expression of Oprm1 28 0.62 6.77 22.79
13 INT5905 Negative_regulation of ELANE 113 0.59 47.43 22.09
14 INT8580 Gene_expression of ELANE 132 0.75 62.98 21.79
15 INT4841 Localization of Npff 26 0.80 4.36 19.91
16 INT21105 Phosphorylation of Oprm1 32 0.82 0.83 19.29
17 INT67975 Gene_expression of Bdkrb2 38 0.68 21.69 17.94
18 INT58495 Positive_regulation of Positive_regulation of Oprm1 22 0.49 2.44 17.66
19 INT16155 Positive_regulation of Npff 25 0.70 6.21 17.58
20 INT6043 Negative_regulation of Binding of Oprm1 24 0.57 2.67 16.78
21 INT46582 Binding of Npff 20 0.48 1.49 13.99
22 INT37803 Positive_regulation of Bdkrb2 18 0.68 14.21 13.99
23 INT4842 Regulation of Npff 13 0.54 4.59 13.62
24 INT68814 Positive_regulation of Transcription of Oprm1 16 0.60 2.72 13.57
25 INT85510 Positive_regulation of Bdkrb2 23 0.70 12.08 12.68
26 INT88223 Gene_expression of Bdkrb2 17 0.69 13.94 11.44
27 INT6044 Regulation of Binding of Oprm1 16 0.61 3.01 11.11
28 INT59766 Positive_regulation of Negative_regulation of Oprm1 9 0.50 1.31 11.08
29 INT71592 Negative_regulation of Gene_expression of Oprm1 11 0.58 4.03 10.37
30 INT49483 Regulation of Positive_regulation of Oprm1 8 0.61 2.34 9.4
31 INT76162 Positive_regulation of Phosphorylation of Oprm1 11 0.69 0.64 8.72
32 INT81597 Transcription of Npff 10 0.69 5.52 8.53
33 INT9573 Regulation of Bdkrb2 9 0.43 6.04 8.41
34 INT18021 Positive_regulation of Binding of Oprm1 16 0.70 2.53 8.38
35 INT2605 Regulation of ELANE 39 0.61 18.22 7.11
36 INT16628 Negative_regulation of Positive_regulation of Oprm1 9 0.43 0.89 6.92
37 INT612 Positive_regulation of Orm1 15 0.68 5.24 6.73
38 INT4840 Positive_regulation of Localization of Npff 7 0.69 0.79 6.69
39 INT65295 Negative_regulation of Bdkrb2 9 0.37 6.36 6.49
40 INT5932 Regulation of Regulation of Oprm1 7 0.61 0.44 6.47
41 INT53135 Positive_regulation of Localization of Oprm1 2 0.50 0 6.12
42 INT81596 Positive_regulation of Gene_expression of Npff 6 0.69 3.41 6.1
43 INT116420 Localization of Elane 16 0.14 7.8 6
44 INT10100 Binding of ELANE 22 0.47 15.32 5.19
45 INT17582 Negative_regulation of Localization of ELANE 17 0.53 6.11 4.89
46 INT53959 Negative_regulation of Npff 6 0.57 0.55 4.86
47 INT70137 Regulation of Bdkrb2 10 0.27 5.45 4.62
48 INT88221 Positive_regulation of Gene_expression of Bdkrb2 5 0.36 3.35 3.91
49 INT114750 Negative_regulation of Gene_expression of Bdkrb2 4 0.17 2.68 3.64
50 INT128679 Negative_regulation of Bdkrb2 7 0.35 6.78 3.54
51 INT179656 Gene_expression of Elane 12 0.32 9.44 3.53
52 INT5929 Positive_regulation of Regulation of Oprm1 4 0.50 0.56 3.48
53 INT22891 Positive_regulation of Localization of ELANE 16 0.69 11.52 3.42
54 INT42581 Regulation of Gene_expression of ELANE 11 0.38 9.25 3.38
55 INT22823 Positive_regulation of Positive_regulation of ELANE 12 0.45 6.89 3.35
56 INT88220 Transcription of Bdkrb2 6 0.65 3.08 3.21
57 INT25674 Positive_regulation of Gene_expression of ELANE 16 0.60 7.46 3.12
58 INT28731 Negative_regulation of Elane 14 0.14 8.97 3.01
59 INT126636 Binding of Bdkrb2 3 0.33 2.18 2.78
60 INT70377 Regulation of Transcription of Oprm1 3 0.47 0.93 2.78
61 INT88222 Positive_regulation of Transcription of Bdkrb2 3 0.47 1.32 2.51
62 INT53960 Negative_regulation of Localization of Npff 3 0.38 0.31 2.34
63 INT71952 Regulation of Negative_regulation of Oprm1 3 0.43 0.09 2.18
64 INT124583 Negative_regulation of Elane 8 0.29 5.26 2.14
65 INT58287 Gene_expression of Orm1 3 0.66 1.17 2.12
66 INT42583 Protein_catabolism of ELANE 8 0.89 4.33 2.11
67 INT51502 Positive_regulation of Elane 5 0.22 2.3 1.94
68 INT36245 Negative_regulation of Gene_expression of ELANE 11 0.40 5.32 1.88
69 INT83358 Positive_regulation of Elane 8 0.21 8.14 1.83
70 INT36581 Binding of Orm1 6 0.48 0.47 1.73
71 INT81598 Regulation of Transcription of Npff 1 0.44 0.78 1.68
72 INT130552 Negative_regulation of Localization of Oprm1 2 0.31 0.37 1.53
73 INT21106 Regulation of Phosphorylation of Oprm1 3 0.61 0 1.43
74 INT85667 Negative_regulation of Negative_regulation of Oprm1 3 0.37 0.54 1.31
75 INT133958 Localization of Bdkrb2 2 0.79 0.65 1.29
76 INT85613 Positive_regulation of Transcription of Npff 2 0.50 0.67 1.28
77 INT170031 Positive_regulation of Positive_regulation of Bdkrb2 1 0.09 0.94 1.27
78 INT14138 Regulation of Localization of Oprm1 1 0.28 0 1.23
79 INT5652 Negative_regulation of Positive_regulation of ELANE 7 0.37 2.46 1.21
80 INT109663 Regulation of Gene_expression of Npff 1 0.62 0.65 1.21
81 INT254634 Positive_regulation of Positive_regulation of Bdkrb2 2 0.32 1.64 1.13
82 INT67974 Positive_regulation of Gene_expression of Bdkrb2 3 0.37 1.13 1.12
83 INT17805 Regulation of Localization of ELANE 7 0.59 1.88 1.08
84 INT616 Regulation of Orm1 4 0.38 1.72 1.08
85 INT242390 Regulation of Gene_expression of Bdkrb2 3 0.31 1.37 1.06
86 INT37802 Regulation of Positive_regulation of Bdkrb2 1 0.23 0.17 1.01
87 INT111048 Binding of Bdkrb2 2 0.47 2.54 1
88 INT21108 Negative_regulation of Phosphorylation of Oprm1 2 0.43 0 0.98
89 INT4839 Regulation of Localization of Npff 1 0.24 0.06 0.97
90 INT58291 Protein_catabolism of Bdkrb2 3 0.08 1.19 0.94
91 INT58292 Negative_regulation of Protein_catabolism of Bdkrb2 1 0.04 0.82 0.94
92 INT141332 Positive_regulation of Binding of Npff 1 0.21 0 0.94
93 INT32443 Negative_regulation of Binding of ELANE 2 0.11 0.54 0.89
94 INT203132 Negative_regulation of Gene_expression of Elane 1 0.20 1.5 0.86
95 INT121906 Positive_regulation of Gene_expression of Orm1 1 0.46 0.08 0.84
96 INT116419 Negative_regulation of Localization of Elane 2 0.01 0.58 0.82
97 INT142422 Regulation of Positive_regulation of ELANE 1 0.02 0.65 0.78
98 INT46295 Regulation of Negative_regulation of ELANE 4 0.39 2.34 0.76
99 INT55921 Negative_regulation of Transcription of Oprm1 1 0.43 0 0.76
100 INT254632 Transcription of Bdkrb2 1 0.36 0.54 0.75
101 INT9928 Negative_regulation of Orm1 3 0.25 1.21 0.73
102 INT271462 Protein_catabolism of Bdkrb2 1 0.58 0.71 0.72
103 INT143814 Regulation of Localization of Bdkrb2 1 0.16 0.38 0.69
104 INT129375 Negative_regulation of Regulation of Oprm1 1 0.28 0.49 0.68
105 INT153008 Gene_expression of Elane 3 0.66 1.66 0.67
106 INT133957 Positive_regulation of Localization of Bdkrb2 1 0.46 0.28 0.63
107 INT51501 Positive_regulation of Positive_regulation of Elane 1 0.09 0.5 0.59
108 INT49236 Localization of Bdkrb2 4 0.52 1.6 0.56
109 INT143813 Regulation of Negative_regulation of Bdkrb2 1 0.16 0.14 0.55
110 INT179665 Protein_catabolism of Elane 3 0.15 3.19 0.52
111 INT179666 Positive_regulation of Gene_expression of Elane 3 0.21 1.84 0.5
112 INT153430 Binding of Elane 2 0.47 1.92 0.48
113 INT235200 Positive_regulation of Negative_regulation of ELANE 3 0.38 1.68 0.46
114 INT133702 Phosphorylation of Npff 1 0.52 0.41 0.4
115 INT252736 Transcription of ELANE 2 0.25 0.94 0.39
116 INT271458 Regulation of Regulation of Bdkrb2 1 0.40 0.36 0.39
117 INT52071 Negative_regulation of Negative_regulation of ELANE 2 0.13 0.78 0.36
118 INT39333 Negative_regulation of Positive_regulation of Orm1 1 0.09 0.4 0.36
119 INT21451 Regulation of Regulation of ELANE 2 0.07 0.06 0.35
120 INT57883 Regulation of Binding of Npff 1 0.45 0 0.31
121 INT18041 Protein_catabolism of Oprm1 1 0.87 0 0.31
122 INT273175 Negative_regulation of Gene_expression of Elane 1 0.04 0.71 0.29
123 INT185122 Regulation of Localization of Elane 1 0.01 0.12 0.27
124 INT273176 Positive_regulation of Gene_expression of Elane 1 0.04 0.63 0.26
125 INT272891 Positive_regulation of Positive_regulation of Elane 1 0.08 1.01 0.25
126 INT272872 Positive_regulation of Protein_catabolism of Elane 1 0.08 1 0.24
127 INT259604 Positive_regulation of Binding of Elane 1 0.09 0.81 0.23
128 INT259617 Negative_regulation of Binding of Elane 1 0.08 0.67 0.16
129 INT111240 Localization of Elane 1 0.78 0.59 0.15
130 INT111241 Negative_regulation of Localization of Elane 1 0.57 0.59 0.15
131 INT272869 Negative_regulation of Negative_regulation of Elane 1 0.06 1.02 0.14
132 INT312139 Regulation of Transcription of ELANE 1 0.16 0.18 0.13
133 INT83359 Regulation of Elane 2 0.11 3.61 0.05
134 INT179651 Negative_regulation of Protein_catabolism of Elane 1 0.04 0.75 0.05
135 INT287710 Regulation of Regulation of Elane 1 0.11 1.38 0.03
136 INT70328 Phosphorylation of ELANE 2 0.29 0.15 0
137 INT107439 Positive_regulation of Binding of Orm1 1 0.40 0 0
138 INT80928 Localization of Orm1 1 0.68 0.28 0
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