GO:0002439

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Name chronic inflammatory response to antigenic stimulus
Categary Process
Go Slim No
Go Link GO:0002439
Unique Molecular Interactions 1290
Total Molecular Interactions 1830
Total Single Events 16654
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for chronic inflammatory response to antigenic stimulus. They are ordered first by their pain relevance and then by number of times they were reported for chronic inflammatory response to antigenic stimulus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT95068 Tlr4 Positive_regulation of IL1B 1 0.03 4.54 5.6
2 INT139706 Tnf Positive_regulation of Ltp 1 0.03 2.61 4.63
3 INT128296 Negative_regulation of IL1B Positive_regulation of Insr 1 0.10 1.36 4.52
4 INT128295 IL1B Positive_regulation of Insr 1 0.11 1.36 4.5
5 INT64718 IL1B Positive_regulation of Gene_expression of IL6 15 0.59 9.37 4.48
6 INT61359 TNF Positive_regulation of NFKB1 11 0.63 6.66 3.89
7 INT57985 Il1b Positive_regulation of Il6 5 0.59 1.66 3.53
8 INT146412 Tnf Positive_regulation of Gene_expression of Trpv1 2 0.66 5.22 3.22
9 INT64719 IL1B Positive_regulation of IL6 7 0.41 6.84 3.14
10 INT150886 Il1a Regulation of Il1b 1 0.02 3.46 2.93
11 INT130721 Binding of IL1B and IL1RN 6 0.05 5.29 2.85
12 INT140024 Tnf Positive_regulation of Gene_expression of Il1b 2 0.49 2.75 2.61
13 INT152501 Binding of Tnf and Tnfrsf1a 4 0.31 3 2.58
14 INT151826 Tnf Positive_regulation of TNF 1 0.04 3.38 2.51
15 INT117532 SETBP1 Positive_regulation of Gene_expression of TNF 1 0.54 0.85 2.44
16 INT122163 Binding of TNF and TNFRSF1B 6 0.44 6.06 2.41
17 INT61733 Tlr4 Positive_regulation of Gene_expression of Tnf 3 0.26 1.99 2.36
18 INT139705 Negative_regulation of Tnf Positive_regulation of Ltp 1 0.03 1.19 2.3
19 INT279361 Binding of TNF and KLF1 4 0.00 3.72 2.19
20 INT94492 Il6 Positive_regulation of Gene_expression of Il1b 1 0.27 3.81 2.19
21 INT94491 Il1b Positive_regulation of Gene_expression of Tnf 1 0.25 3.81 2.19
22 INT94504 Il6 Positive_regulation of Gene_expression of Tnf 1 0.30 3.8 2.19
23 INT94494 Il1b Positive_regulation of Gene_expression of Il6 1 0.27 3.81 2.19
24 INT86179 TNF Positive_regulation of Localization of IL6 5 0.35 1.66 2.17
25 INT209924 IL1B Negative_regulation of PPARA 1 0.20 4.38 2.17
26 INT148704 Binding of TNF and TNFRSF1A 5 0.44 3.3 2.09
27 INT196586 Negative_regulation of Mapk14 Negative_regulation of TNF 2 0.04 2.02 2.08
28 INT140032 Tnf Positive_regulation of Gene_expression of Ifng 2 0.43 2.23 2
29 INT140026 Il1b Positive_regulation of Gene_expression of Tnf 2 0.49 2.23 2
30 INT217042 IRF6 Positive_regulation of TNF 4 0.27 3.03 1.95
31 INT129212 RYBP Positive_regulation of Tnf 2 0.03 1.9 1.95
32 INT279359 Binding of ADA and TNF 1 0.20 2.61 1.91
33 INT51051 IL1B Positive_regulation of Localization of IL6 7 0.57 3.79 1.87
34 INT81920 Binding of IL1B and NFKB1 1 0.04 1.54 1.85
35 INT50993 Il1b Positive_regulation of Fos 2 0.40 0.43 1.84
36 INT199287 TNF Positive_regulation of Transcription of Oprm1 2 0.02 1.86 1.8
37 INT224432 TNF Positive_regulation of Gene_expression of VEGFA 1 0.13 5.83 1.8
38 INT137207 Tnf Positive_regulation of Nfkb1 3 0.23 2.69 1.71
39 INT167427 Mapk8 Regulation of Regulation of Tnf 1 0.26 2.83 1.7
40 INT89379 TNF Positive_regulation of Gene_expression of IL6 5 0.50 4.37 1.69
41 INT100274 IL1RN Negative_regulation of IL1B 5 0.53 1.79 1.65
42 INT83093 IL1B Positive_regulation of BDKRB1 1 0.51 0.44 1.65
43 INT61134 IL10 Negative_regulation of Gene_expression of IL1B 3 0.46 2.13 1.63
44 INT79778 Tlr4 Positive_regulation of Localization of TNF 4 0.08 4.21 1.61
45 INT167202 TNF Regulation of Gene_expression of Ngf 1 0.10 1.47 1.6
46 INT209853 TNF Regulation of Gene_expression of CD36 1 0.61 3.41 1.59
47 INT266767 SFTPA1 Positive_regulation of Gene_expression of TNF 1 0.01 1.69 1.59
48 INT74937 IL1B Positive_regulation of CPOX 5 0.18 1.13 1.55
49 INT198653 TNF Positive_regulation of MIF 1 0.15 3.81 1.55
50 INT252633 Binding of TNF and Tnfrsf1b 4 0.05 3.66 1.54
51 INT91456 IL1B Positive_regulation of Gene_expression of CPOX 6 0.17 3.36 1.53
52 INT167201 Gtf3a Regulation of TNF 1 0.01 1.39 1.52
53 INT158775 Regulation of Tnf Regulation of Ephb1 1 0.18 0.09 1.52
54 INT158777 Tnf Regulation of Ephb1 1 0.18 0.09 1.51
55 INT10276 Il1b Regulation of Gene_expression of Penk 1 0.61 0.85 1.5
56 INT140029 Ifng Positive_regulation of Gene_expression of Tnf 1 0.43 1.69 1.5
57 INT150887 Il1b Regulation of Il10 1 0.04 1.74 1.47
58 INT158776 Il1b Regulation of Ephb1 1 0.15 0.09 1.46
59 INT285569 TNF Negative_regulation of Gene_expression of Il6 1 0.03 2.83 1.46
60 INT72755 Tap1 Negative_regulation of TNF 1 0.43 2.45 1.46
61 INT131156 Binding of RUNX1 and TNF 2 0.03 3.44 1.42
62 INT197111 Binding of IL1B and MCF2 1 0.02 2.12 1.4
63 INT161513 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Tnf 1 0.33 0.27 1.35
64 INT160588 TNF Positive_regulation of Gene_expression of OPRM1 1 0.20 0.54 1.35
65 INT56087 TNF Regulation of Gene_expression of SERPINE1 1 0.43 1.67 1.33
66 INT95093 ITIH4 Positive_regulation of IL1B 1 0.43 1.04 1.32
67 INT95094 Negative_regulation of ITIH4 Positive_regulation of IL1B 1 0.36 1.04 1.32
68 INT121705 IL1B Positive_regulation of Gene_expression of MMP3 3 0.49 1.2 1.3
69 INT186393 Binding of TNF and Tnfrsf1a 9 0.37 8.55 1.29
70 INT130333 FUT3 Negative_regulation of Positive_regulation of Tnf 1 0.01 0.36 1.29
71 INT108386 IL1B Positive_regulation of MMP1 3 0.27 1.56 1.28
72 INT121703 IL1B Positive_regulation of Gene_expression of MMP1 3 0.49 1.14 1.27
73 INT70037 TNF Regulation of IL10 2 0.09 2.11 1.26
74 INT296796 Tbrs1 Positive_regulation of Gene_expression of TNF 1 0.00 1.58 1.26
75 INT108389 IL1B Positive_regulation of ADAMTS4 1 0.51 1.19 1.24
76 INT197092 TNF Regulation of VEGFA 4 0.21 2.78 1.22
77 INT131807 Bpifa2 Positive_regulation of Localization of Tnf 1 0.32 2.09 1.22
78 INT70035 TNF Regulation of Negative_regulation of PRF1 1 0.05 1.42 1.21
79 INT70039 IL1B Regulation of Negative_regulation of IL10 1 0.07 1.42 1.21
80 INT70032 TNF Regulation of PRF1 1 0.05 1.42 1.21
81 INT70040 TNF Regulation of Negative_regulation of IL10 1 0.09 1.42 1.21
82 INT70038 IL1B Regulation of PRF1 1 0.05 1.42 1.21
83 INT328743 TNF Positive_regulation of Mapk14 1 0.04 1.4 1.21
84 INT70031 IL1B Regulation of Negative_regulation of PRF1 1 0.05 1.42 1.21
85 INT70030 IL1B Regulation of IL10 1 0.07 1.42 1.21
86 INT194861 Binding of IL1B and IL1R1 2 0.01 1.55 1.2
87 INT209926 IL1B Regulation of PPARA 1 0.21 2.45 1.2
88 INT194619 Il15 Positive_regulation of Gene_expression of TNF 1 0.24 2.23 1.2
89 INT133046 TNF Positive_regulation of Positive_regulation of NFKB1 5 0.54 3.23 1.19
90 INT113242 TNF Regulation of Transcription of OPRM1 2 0.45 1.53 1.19
91 INT314196 Ngf Positive_regulation of Tnf 1 0.50 1.98 1.18
92 INT289465 IRF6 Positive_regulation of IL1B 3 0.05 0.9 1.16
93 INT94502 Il1b Positive_regulation of Gene_expression of Avp 1 0.28 1.97 1.15
94 INT94509 Il1b Positive_regulation of Gene_expression of AVP 1 0.36 1.96 1.15
95 INT231769 TNF Negative_regulation of Gene_expression of HMOX1 1 0.26 4.75 1.15
96 INT66767 Il1b Positive_regulation of Pla2g10 1 0.05 0.47 1.13
97 INT94498 Il1b Positive_regulation of Gene_expression of Crh 1 0.24 1.94 1.13
98 INT72754 Adamts7 Negative_regulation of TNF 1 0.28 1.64 1.13
99 INT89938 Tlr4 Positive_regulation of Gene_expression of TNF 6 0.25 1.3 1.12
100 INT66907 Il1b Positive_regulation of Localization of Oxt 2 0.78 0.18 1.12
101 INT107264 Binding of TNF and NCR3 1 0.30 1.42 1.1
102 INT139704 Tnf Positive_regulation of Mapk14 1 0.22 0.73 1.1
103 INT107266 Binding of HLA-DRB1 and TNF 1 0.29 1.41 1.1
104 INT267597 IL10 Negative_regulation of Gene_expression of TNF 1 0.03 2.24 1.1
105 INT107267 Binding of HLA-A and TNF 1 0.34 1.41 1.1
106 INT57982 Il1b Positive_regulation of Crh 2 0.38 0.98 1.09
107 INT94495 Tnf Positive_regulation of Gene_expression of Il6 1 0.30 1.9 1.09
108 INT107562 Penk Positive_regulation of Localization of Il1b 1 0.20 0.09 1.09
109 INT107561 Mtr Positive_regulation of Localization of Il1b 1 0.04 0.09 1.09
110 INT74939 IL1B Positive_regulation of Gene_expression of HGF 1 0.58 0.72 1.09
111 INT151825 Tnf Positive_regulation of Mapk14 1 0.22 1.72 1.09
112 INT94500 Tnf Positive_regulation of Gene_expression of Il1b 1 0.25 1.9 1.09
113 INT107567 Hps4 Positive_regulation of Localization of Il1b 1 0.01 0.09 1.08
114 INT139703 Tnf Positive_regulation of Mapk8 1 0.32 0.73 1.08
115 INT152502 Tnf Negative_regulation of Binding of Tnfrsf1a 1 0.37 0.6 1.08
116 INT119108 Binding of LTBR and TNF 2 0.15 1.47 1.07
117 INT107564 Hps4 Regulation of Localization of Il1b 1 0.01 0.1 1.07
118 INT107560 Penk Regulation of Localization of Il1b 1 0.18 0.1 1.07
119 INT114364 Hmgb1 Positive_regulation of Gene_expression of TNF 2 0.05 1.85 1.06
120 INT57986 Il1b Regulation of Positive_regulation of Il6 2 0.39 0.23 1.05
121 INT120312 Ghrh Regulation of Tnf 1 0.26 0.95 1.05
122 INT120314 Ghrh Regulation of Positive_regulation of Tnf 1 0.43 0.95 1.05
123 INT152504 Binding of CR1 and Tnf 1 0.00 0.49 1.04
124 INT133650 Epo Negative_regulation of TNF 1 0.35 2.7 1.04
125 INT65986 IL1B Positive_regulation of PTGS2 3 0.32 2.05 1.03
126 INT128297 Il1b Positive_regulation of CRH 1 0.02 0.27 1.03
127 INT156245 NFKB1 Positive_regulation of Regulation of TNF 1 0.45 0.76 1.03
128 INT81545 Tnf Positive_regulation of Gtf3a 2 0.03 1.41 1.02
129 INT271875 IL1RN Negative_regulation of Binding of IL1B 1 0.01 1.3 1.01
130 INT308804 Pld1 Positive_regulation of TNF 1 0.05 2.42 0.99
131 INT102690 IL1B Positive_regulation of ITGAL 1 0.05 0.87 0.99
132 INT274895 Positive_regulation of Cbr2 Negative_regulation of Gene_expression of TNF 1 0.06 1.21 0.99
133 INT103651 IL1B Positive_regulation of Gene_expression of IL8 6 0.78 1.23 0.98
134 INT103796 IL1B Positive_regulation of Gene_expression of SELE 2 0.08 1 0.98
135 INT129216 Negative_regulation of RYBP Positive_regulation of Tnf 1 0.01 1.24 0.98
136 INT182022 TNF Positive_regulation of Gene_expression of Tnfrsf11b 1 0.06 1.56 0.98
137 INT209852 TNF Negative_regulation of Gene_expression of CD36 1 0.43 0.61 0.98
138 INT154255 Tnf Positive_regulation of IL1B 1 0.54 0.94 0.97
139 INT154254 Tnf Positive_regulation of Il6 1 0.36 0.94 0.97
140 INT159111 Il1a Regulation of Gene_expression of Il1b 1 0.49 0.38 0.97
141 INT114320 TNF Positive_regulation of Gene_expression of Il6 1 0.07 1.73 0.97
142 INT103133 TNF Positive_regulation of Gene_expression of IL8 2 0.48 1.26 0.96
143 INT240123 MIR885 Negative_regulation of IL1B 1 0.01 1.57 0.96
144 INT133652 Epo Negative_regulation of Gene_expression of TNF 1 0.35 2.64 0.96
145 INT171264 TNF Positive_regulation of MMP1 2 0.10 2.05 0.95
146 INT188805 TNF Positive_regulation of Gene_expression of Crp 1 0.15 2.96 0.95
147 INT130722 Binding of IL1B and Nfkb1 1 0.28 1.23 0.95
148 INT100018 TNF Positive_regulation of MAPK1 3 0.24 1.56 0.94
149 INT133050 TNF Positive_regulation of Gene_expression of ICAM1 3 0.67 1.91 0.94
150 INT182024 TNF Positive_regulation of Gene_expression of Il6 1 0.05 1.58 0.94
151 INT129211 RYBP Positive_regulation of Gene_expression of Tnf 1 0.01 1.04 0.94
152 INT130725 Binding of IL1B and Il1rn 1 0.01 1.16 0.93
153 INT81919 Binding of HSF1 and IL1B 1 0.42 0.77 0.93
154 INT155259 RUNX1 Negative_regulation of Tnf 1 0.00 1.48 0.93
155 INT165280 Tnf Positive_regulation of Gene_expression of Nos2 1 0.24 1.02 0.91
156 INT254242 TNF Positive_regulation of Gene_expression of DKK1 1 0.14 1.24 0.91
157 INT256646 Tnf Positive_regulation of Positive_regulation of Nfkb1 1 0.22 1.83 0.9
158 INT222988 TNF Positive_regulation of Protein_catabolism of COL1A1 1 0.01 1.66 0.9
159 INT211128 Binding of P4HB and TNF 1 0.09 0.97 0.9
160 INT211129 Negative_regulation of Binding of P4HB and TNF 1 0.10 0.97 0.9
161 INT120147 Tlr4 Positive_regulation of Tnf 3 0.39 2.14 0.89
162 INT80132 Binding of HLA-B and TNF 1 0.04 1.15 0.89
163 INT142278 Slc8a1 Regulation of Tnf 1 0.14 0.07 0.89
164 INT63943 Il1b Positive_regulation of Localization of Calca 2 0.46 0.98 0.88
165 INT167466 Ccdc80 Negative_regulation of Tnf 1 0.01 0.76 0.88
166 INT151630 Il1rn Negative_regulation of Dock9 1 0.03 1.33 0.88
167 INT136349 Il1b Positive_regulation of Positive_regulation of Oprl1 1 0.22 0.27 0.88
168 INT134311 Tnf Positive_regulation of Protein_catabolism of Nfkbia 1 0.18 0.57 0.88
169 INT209928 IL1B Positive_regulation of MAPK14 2 0.15 1.69 0.87
170 INT116556 Olr1627 Negative_regulation of Regulation of Tnf 1 0.01 1.52 0.87
171 INT224585 IL1B Positive_regulation of IL1RN 1 0.02 1.3 0.87
172 INT97795 IRF6 Positive_regulation of Localization of TNF 3 0.09 1.57 0.86
173 INT152868 Tnf Regulation of Gene_expression of Trpv1 1 0.27 0.25 0.86
174 INT110315 Negative_regulation of ALOX5 Negative_regulation of Gene_expression of TNF 1 0.47 0.74 0.85
175 INT215598 Positive_regulation of P2rx7 Positive_regulation of Localization of TNF 1 0.22 1.44 0.85
176 INT196638 TNF Positive_regulation of F2RL1 2 0.09 1.52 0.84
177 INT196632 IL1B Positive_regulation of F2RL1 2 0.05 1.52 0.84
178 INT146919 Tnf Positive_regulation of Gene_expression of Ccl2 1 0.16 1.44 0.84
179 INT238641 Binding of TNF and Ifx 1 0.07 0.86 0.84
180 INT238642 Binding of TNF and Ada 1 0.03 0.86 0.84
181 INT105435 TNF Positive_regulation of IL6 5 0.25 4.45 0.83
182 INT10275 Il1b Positive_regulation of Gene_expression of Penk 1 0.49 0.75 0.83
183 INT149626 Il1b Regulation of Gene_expression of Tnf 1 0.41 0.83 0.83
184 INT65011 IL1B Positive_regulation of PTGER2 4 0.08 0.92 0.82
185 INT102201 Tnf Regulation of Il1b 3 0.39 2.57 0.82
186 INT162071 Gene_expression of MC1R Negative_regulation of Gene_expression of TNF 1 0.41 0.34 0.82
187 INT66206 Negative_regulation of TNF Positive_regulation of NFKB1 2 0.53 1.71 0.81
188 INT83094 IL1B Positive_regulation of Positive_regulation of BDKRB1 1 0.45 0.2 0.81
189 INT126555 Binding of Ighg1 and Tnf 1 0.35 2.2 0.8
190 INT147755 Binding of GNRH1 and TNF 1 0.32 2.37 0.79
191 INT110518 Tnf Positive_regulation of Prkce 1 0.26 1.43 0.78
192 INT188531 Binding of TNF and PDXK 1 0.03 1.99 0.78
193 INT102163 Binding of TNF and Mmp9 1 0.12 0.88 0.78
194 INT306259 HDAC9 Negative_regulation of Gene_expression of TNF 1 0.21 0.89 0.78
195 INT102161 Binding of TNF and Mmp2 1 0.10 0.88 0.78
196 INT306258 HDAC4 Negative_regulation of Gene_expression of TNF 1 0.09 0.89 0.78
197 INT130138 TNF Negative_regulation of Gene_expression of S100A10 1 0.06 1.32 0.78
198 INT102162 Binding of TNF and Adam17 1 0.14 0.88 0.78
199 INT296797 Tlr9 Regulation of Positive_regulation of TNF 1 0.03 1.37 0.77
200 INT296798 Gopc Regulation of Positive_regulation of TNF 1 0.01 1.37 0.77

Single Events

The table below shows the top 100 pain related interactions that have been reported for chronic inflammatory response to antigenic stimulus. They are ordered first by their pain relevance and then by number of times they were reported in chronic inflammatory response to antigenic stimulus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82
2 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98
3 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81
4 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68
5 INT6852 Localization of TNF 883 0.81 705.95 270.84
6 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97
7 INT6481 Binding of TNF 624 0.48 510.2 214.82
8 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210
9 INT6488 Gene_expression of Tnf 484 0.78 339.61 191.58
10 INT13353 Positive_regulation of Tnf 332 0.70 248.75 148.1
11 INT9660 Regulation of TNF 363 0.62 312.94 139.99
12 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61
13 INT10272 Gene_expression of Il1b 194 0.78 121.02 103.03
14 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9
15 INT10166 Localization of Tnf 237 0.81 153.95 88.64
16 INT10274 Positive_regulation of Il1b 123 0.70 79.76 73.56
17 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99
18 INT11380 Negative_regulation of IL1B 215 0.59 125.62 72.35
19 INT58400 Negative_regulation of Tnf 182 0.59 129.97 71
20 INT49995 Positive_regulation of Gene_expression of Tnf 187 0.70 125.07 70.54
21 INT6849 Localization of IL1B 229 0.81 112.56 69.63
22 INT6489 Positive_regulation of Gene_expression of Tnf 140 0.70 92.31 67.85
23 INT6486 Positive_regulation of Tnf 168 0.70 123.47 66.05
24 INT52800 Negative_regulation of Gene_expression of Tnf 142 0.59 92.27 55.47
25 INT22112 Positive_regulation of Localization of TNF 164 0.70 115.66 52.18
26 INT6473 Positive_regulation of Gene_expression of IL1B 204 0.70 117.23 50.86
27 INT66029 Negative_regulation of Tnf 100 0.59 84.28 48.16
28 INT55670 Negative_regulation of Gene_expression of Tnf 83 0.59 57.16 46.33
29 INT5307 Regulation of Tnf 87 0.62 78.71 43.4
30 INT13354 Transcription of TNF 108 0.72 85.81 42.32
31 INT9233 Negative_regulation of Gene_expression of IL1B 114 0.59 56.99 41.82
32 INT5973 Regulation of IL1B 109 0.62 66.6 39.88
33 INT53577 Negative_regulation of Localization of TNF 110 0.59 59.28 35.23
34 INT6484 Binding of IL1B 122 0.47 75.84 35.07
35 INT35406 Localization of Tnf 94 0.81 64.63 31.65
36 INT9347 Localization of Il1b 58 0.81 26.13 31.53
37 INT52801 Regulation of Gene_expression of Tnf 55 0.62 48.74 26.59
38 INT10273 Positive_regulation of Gene_expression of Il1b 47 0.68 31.15 26.21
39 INT5948 Regulation of Il1b 44 0.60 22.8 25.4
40 INT10349 Negative_regulation of Il1b 48 0.58 25.53 24.24
41 INT66753 Negative_regulation of Positive_regulation of Tnf 45 0.59 35.28 22.33
42 INT8483 Positive_regulation of Positive_regulation of TNF 73 0.67 60.35 22.03
43 INT53575 Regulation of Gene_expression of Tnf 46 0.62 34.35 20.63
44 INT9237 Regulation of Gene_expression of IL1B 49 0.62 30.69 20.34
45 INT53574 Regulation of Tnf 45 0.62 40.68 19.71
46 INT66751 Negative_regulation of Localization of Tnf 48 0.59 26 19.36
47 INT66755 Transcription of Tnf 45 0.72 37.1 19.11
48 INT36054 Transcription of IL1B 53 0.72 32.64 17.31
49 INT10169 Positive_regulation of Localization of Tnf 44 0.70 27.71 16.75
50 INT19929 Negative_regulation of Positive_regulation of TNF 52 0.59 38.16 16.51
51 INT49986 Transcription of Tnf 25 0.72 18.3 16.22
52 INT12087 Regulation of Localization of TNF 44 0.62 28.71 15.17
53 INT49606 Gene_expression of Il1rn 30 0.66 15.78 14.82
54 INT25266 Positive_regulation of Localization of IL1B 38 0.69 15.89 14.35
55 INT10173 Binding of Tnf 45 0.48 35.6 14.32
56 INT64048 Positive_regulation of Positive_regulation of Tnf 32 0.70 21.24 13.74
57 INT29170 Negative_regulation of Gene_expression of Il1b 25 0.59 16.36 13.68
58 INT19191 Negative_regulation of Localization of IL1B 35 0.58 15.19 13.63
59 INT6478 Negative_regulation of Binding of TNF 36 0.58 30.42 13.31
60 INT89404 Regulation of Negative_regulation of TNF 30 0.45 24.47 12.71
61 INT51265 Phosphorylation of TNF 32 0.81 25.33 10.75
62 INT60434 Negative_regulation of Positive_regulation of Tnf 20 0.46 10.01 10.64
63 INT50196 Transcription of Il1b 25 0.69 19.08 10.43
64 INT80110 Regulation of Positive_regulation of TNF 34 0.44 25.79 9.78
65 INT48860 Regulation of Localization of Tnf 25 0.61 20.68 8.78
66 INT53573 Negative_regulation of Localization of Tnf 19 0.59 11.57 8.54
67 INT86411 Negative_regulation of Negative_regulation of TNF 24 0.42 17.6 7.89
68 INT50195 Positive_regulation of Positive_regulation of Il1b 12 0.67 7.41 7.64
69 INT49490 Positive_regulation of Transcription of TNF 19 0.70 14.76 7.58
70 INT68299 Binding of Tnf 17 0.39 12.55 7.49
71 INT11378 Negative_regulation of Positive_regulation of IL1B 23 0.59 10.28 7.26
72 INT66752 Positive_regulation of Transcription of Tnf 15 0.68 10.86 7.26
73 INT36053 Positive_regulation of Positive_regulation of IL1B 22 0.70 11.41 6.84
74 INT612 Positive_regulation of Orm1 15 0.68 5.24 6.73
75 INT69980 Negative_regulation of Il1rn 11 0.33 7.75 6.7
76 INT48954 Positive_regulation of Localization of Il1b 13 0.53 8.16 6.44
77 INT67130 Negative_regulation of Localization of Il1b 7 0.57 1.36 6.42
78 INT69985 Positive_regulation of Negative_regulation of TNF 21 0.50 13.26 6.31
79 INT172084 Positive_regulation of Binding of TNF 21 0.50 15.31 6.06
80 INT107441 Positive_regulation of Gene_expression of Il1rn 7 0.46 3.24 5.95
81 INT67060 Negative_regulation of Transcription of TNF 17 0.59 12.94 5.88
82 INT6487 Positive_regulation of Positive_regulation of Tnf 21 0.56 16.06 5.64
83 INT55578 Regulation of Gene_expression of Il1b 7 0.62 4.74 5.55
84 INT10705 Binding of Il1b 9 0.36 2.8 5.53
85 INT58145 Positive_regulation of Localization of Tnf 20 0.67 13.33 5.44
86 INT50197 Positive_regulation of Transcription of Il1b 11 0.50 8.95 5.41
87 INT92054 Positive_regulation of Transcription of Tnf 8 0.50 4.93 5.05
88 INT55698 Regulation of Binding of TNF 13 0.44 8.98 4.74
89 INT16047 Negative_regulation of Positive_regulation of Il1b 11 0.57 5.27 4.66
90 INT76683 Positive_regulation of Il1rn 9 0.51 9.3 4.41
91 INT19190 Regulation of Localization of IL1B 14 0.50 8.71 4.12
92 INT66754 Negative_regulation of Transcription of Tnf 11 0.43 8.43 3.93
93 INT23088 Phosphorylation of Tnf 15 0.79 9.85 3.82
94 INT172173 Protein_catabolism of TNF 16 0.96 9.95 3.79
95 INT83646 Binding of Il1rn 12 0.37 4.41 3.51
96 INT40232 Transcription of Il1rn 8 0.53 9.6 3.37
97 INT65427 Regulation of Positive_regulation of Tnf 7 0.60 3.49 3.22
98 INT95049 Negative_regulation of Regulation of Tnf 4 0.42 1.64 2.84
99 INT6479 Negative_regulation of Binding of IL1B 10 0.43 5.1 2.78
100 INT112147 Positive_regulation of Negative_regulation of Il1b 3 0.49 3.42 2.77
101 INT10350 Negative_regulation of Regulation of Il1b 3 0.41 0.58 2.69
102 INT75736 Regulation of Localization of Tnf 6 0.62 4.61 2.67
103 INT11379 Positive_regulation of Negative_regulation of IL1B 9 0.49 7.2 2.64
104 INT15144 Protein_catabolism of IL1B 11 0.92 4.67 2.58
105 INT98607 Regulation of Regulation of TNF 8 0.44 6.95 2.56
106 INT76679 Positive_regulation of Transcription of Il1rn 1 0.37 9.13 2.55
107 INT62064 Negative_regulation of Gene_expression of Il1rn 6 0.32 4.81 2.53
108 INT69981 Positive_regulation of Negative_regulation of Il1rn 2 0.09 3.28 2.48
109 INT66804 Negative_regulation of Negative_regulation of Tnf 4 0.56 2.79 2.26
110 INT131928 Localization of Il1rn 3 0.74 2.22 2.24
111 INT36055 Positive_regulation of Transcription of IL1B 9 0.49 6.24 2.21
112 INT114898 Regulation of Transcription of TNF 4 0.35 2.69 2.18
113 INT58287 Gene_expression of Orm1 3 0.66 1.17 2.12
114 INT73906 Regulation of Transcription of IL1B 5 0.56 3.46 2.1
115 INT55035 Negative_regulation of Negative_regulation of Il1b 4 0.43 1.46 2.02
116 INT168275 Phosphorylation of Il1b 1 0.79 2.39 2.01
117 INT122649 Positive_regulation of Regulation of Tnf 2 0.49 2.78 1.96
118 INT171323 Phosphorylation of IL1B 5 0.57 4.13 1.94
119 INT14246 Regulation of Positive_regulation of IL1B 7 0.44 3.04 1.77
120 INT77801 Negative_regulation of Binding of Tnf 5 0.42 3.93 1.77
121 INT36581 Binding of Orm1 6 0.48 0.47 1.73
122 INT116498 Negative_regulation of Negative_regulation of IL1B 7 0.41 3.08 1.7
123 INT159957 Positive_regulation of Phosphorylation of Tnf 3 0.49 2.63 1.65
124 INT73901 Negative_regulation of Transcription of IL1B 3 0.53 0.46 1.57
125 INT183791 Positive_regulation of Phosphorylation of TNF 6 0.49 4.72 1.56
126 INT61967 Positive_regulation of Negative_regulation of Tnf 3 0.50 2.46 1.49
127 INT83659 Negative_regulation of Binding of Tnf 3 0.37 1.57 1.42
128 INT173114 Positive_regulation of Binding of IL1B 6 0.49 2.56 1.22
129 INT101022 Regulation of Il1rn 5 0.44 2.15 1.21
130 INT616 Regulation of Orm1 4 0.38 1.72 1.08
131 INT129587 Protein_catabolism of Tnf 2 0.86 1.41 1.08
132 INT168276 Negative_regulation of Phosphorylation of Tnf 1 0.19 1.3 1.08
133 INT135027 Regulation of Positive_regulation of Tnf 3 0.38 2.84 1.05
134 INT9348 Regulation of Localization of Il1b 2 0.27 0.14 1.04
135 INT25264 Regulation of Negative_regulation of IL1B 3 0.27 1.17 1.02
136 INT50989 Regulation of Positive_regulation of Il1b 2 0.42 0.86 1.02
137 INT346201 Negative_regulation of Phosphorylation of IL1B 1 0.20 1.69 1.01
138 INT292529 Phosphorylation of Il1rn 1 0.09 1 0.97
139 INT145851 Negative_regulation of Positive_regulation of Il1rn 1 0.08 0.7 0.95
140 INT145852 Negative_regulation of Negative_regulation of Il1rn 1 0.08 0.69 0.93
141 INT168280 Positive_regulation of Phosphorylation of Il1b 1 0.49 1.1 0.93
142 INT134307 Negative_regulation of Protein_catabolism of Tnf 1 0.41 0.57 0.88
143 INT115822 Regulation of Transcription of Tnf 3 0.35 1.96 0.87
144 INT134310 Positive_regulation of Protein_catabolism of Tnf 1 0.49 0.57 0.87
145 INT121906 Positive_regulation of Gene_expression of Orm1 1 0.46 0.08 0.84
146 INT136690 Regulation of Negative_regulation of Tnf 5 0.45 3.58 0.78
147 INT102199 Regulation of Transcription of Tnf 2 0.45 2.25 0.78
148 INT237158 Negative_regulation of Negative_regulation of Tnf 2 0.13 1.37 0.74
149 INT9928 Negative_regulation of Orm1 3 0.25 1.21 0.73
150 INT127822 Negative_regulation of Transcription of Il1b 2 0.42 1.2 0.72
151 INT88190 Negative_regulation of Binding of Il1rn 1 0.36 0.46 0.68
152 INT51263 Regulation of Phosphorylation of TNF 2 0.26 1.06 0.63
153 INT235079 Negative_regulation of Phosphorylation of TNF 2 0.41 1.16 0.6
154 INT81352 Negative_regulation of Regulation of IL1B 2 0.41 0.51 0.58
155 INT141194 Regulation of Negative_regulation of Tnf 3 0.42 1.57 0.47
156 INT138003 Positive_regulation of Negative_regulation of Tnf 2 0.49 2.07 0.43
157 INT72086 Regulation of Regulation of Tnf 1 0.45 0.3 0.4
158 INT91975 Regulation of Binding of IL1B 2 0.14 0.66 0.38
159 INT159782 Phosphorylation of Tnf 2 0.79 1.51 0.36
160 INT39333 Negative_regulation of Positive_regulation of Orm1 1 0.09 0.4 0.36
161 INT143535 Protein_catabolism of Tnf 2 0.86 3.43 0.33
162 INT209937 Negative_regulation of Protein_catabolism of IL1B 2 0.24 1.15 0.32
163 INT116034 Negative_regulation of Transcription of Tnf 2 0.41 0.17 0.29
164 INT155532 Regulation of Regulation of IL1B 2 0.26 0.32 0.22
165 INT194643 Positive_regulation of Regulation of TNF 2 0.28 2.4 0.21
166 INT81351 Negative_regulation of Regulation of TNF 1 0.33 0.23 0.21
167 INT281991 Regulation of Negative_regulation of Il1b 1 0.03 0.77 0.2
168 INT159783 Positive_regulation of Phosphorylation of Tnf 1 0.12 0.39 0.19
169 INT251578 Positive_regulation of Protein_catabolism of TNF 1 0.41 0.26 0.16
170 INT170142 Regulation of Protein_catabolism of Tnf 1 0.44 1.53 0.13
171 INT134981 Positive_regulation of Regulation of IL1B 2 0.49 0.69 0.1
172 INT295324 Regulation of Binding of Tnf 2 0.44 1.11 0.09
173 INT340415 Regulation of Gene_expression of Il1rn 1 0.27 1.02 0.07
174 INT192301 Positive_regulation of Protein_catabolism of IL1B 1 0.18 0.15 0.03
175 INT159591 Positive_regulation of Binding of Tnf 1 0.43 0.06 0
176 INT16046 Regulation of Regulation of Il1b 1 0.45 0 0
177 INT107439 Positive_regulation of Binding of Orm1 1 0.40 0 0
178 INT80928 Localization of Orm1 1 0.68 0.28 0
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