GO:0002446

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Name neutrophil mediated immunity
Categary Process
Go Slim No
Go Link GO:0002446
Unique Molecular Interactions 441
Total Molecular Interactions 683
Total Single Events 6378
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for neutrophil mediated immunity. They are ordered first by their pain relevance and then by number of times they were reported for neutrophil mediated immunity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT64718 IL1B Positive_regulation of Gene_expression of IL6 15 0.59 9.37 4.48
2 INT64719 IL1B Positive_regulation of IL6 7 0.41 6.84 3.14
3 INT86180 SFTPA1 Positive_regulation of Localization of IL6 2 0.06 2.01 2.85
4 INT115367 Binding of IL6 and IL6R 12 0.07 8.16 2.36
5 INT124121 IL6 Positive_regulation of CCL2 1 0.26 1.84 2.25
6 INT124120 IL6 Regulation of CCL2 1 0.15 1.8 2.22
7 INT86179 TNF Positive_regulation of Localization of IL6 5 0.35 1.66 2.17
8 INT70043 IL6 Regulation of IL10 3 0.18 3.59 2.01
9 INT278937 LEP Positive_regulation of Gene_expression of IL6 1 0.32 3.42 1.97
10 INT51051 IL1B Positive_regulation of Localization of IL6 7 0.57 3.79 1.87
11 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87
12 INT89379 TNF Positive_regulation of Gene_expression of IL6 5 0.50 4.37 1.69
13 INT213071 IL6 Positive_regulation of Gene_expression of CRP 4 0.52 6.58 1.68
14 INT326509 Binding of ACE and VWF 1 0.05 2.07 1.59
15 INT155371 VIP Positive_regulation of Localization of IL6 1 0.64 3.37 1.44
16 INT236365 Binding of CD40LG and IL6 3 0.20 4.16 1.42
17 INT172834 Binding of IL6 and T2dm2 1 0.00 6.4 1.4
18 INT218309 Binding of CRP and IL6 3 0.23 4.78 1.36
19 INT160586 IL6 Positive_regulation of Gene_expression of OPRM1 1 0.14 0.54 1.35
20 INT121190 KCNMA1 Positive_regulation of Gene_expression of IL6 1 0.03 0.54 1.24
21 INT162343 Positive_regulation of KCNMA1 Positive_regulation of ACE 1 0.06 1.25 1.23
22 INT162344 KCNMA1 Positive_regulation of ACE 1 0.06 1.25 1.23
23 INT121189 KCNMA1 Positive_regulation of IL6 1 0.04 0.54 1.23
24 INT70033 IL6 Regulation of PRF1 1 0.03 1.42 1.21
25 INT70047 IL6 Regulation of Negative_regulation of PRF1 1 0.03 1.42 1.21
26 INT70029 IL6 Regulation of Negative_regulation of IL10 1 0.05 1.42 1.21
27 INT24796 ACE Positive_regulation of Localization of HMMR 1 0.00 0.58 1.16
28 INT294710 CRP Positive_regulation of Gene_expression of IL6 1 0.63 1.9 1.12
29 INT83616 Binding of IL6 and IL8 5 0.09 5.8 1.11
30 INT267588 IL10 Negative_regulation of Gene_expression of IL6 1 0.01 2.25 1.11
31 INT61617 PTGER2 Regulation of Gene_expression of IL6 3 0.11 1.13 1.02
32 INT87025 ZAK Positive_regulation of Gene_expression of IL6 2 0.11 1.59 1.02
33 INT218310 IL6 Positive_regulation of Localization of CRP 1 0.29 3.33 1.02
34 INT206074 Binding of IL6 and IL6ST 7 0.32 3.79 1.01
35 INT278946 IL6 Regulation of Gene_expression of IL8 1 0.20 1.9 1
36 INT86181 SFTPA1 Positive_regulation of IL6 1 0.07 0.32 0.99
37 INT244133 DDB1 Positive_regulation of Gene_expression of IL6 1 0.01 1.91 0.99
38 INT299988 IL6 Positive_regulation of Localization of IL8 1 0.05 0.81 0.94
39 INT285418 IRF6 Positive_regulation of Localization of IL6 3 0.05 0.66 0.93
40 INT134785 Il2rb Regulation of Gene_expression of IL6 1 0.00 1.16 0.92
41 INT134784 Il2rb Regulation of IL6 1 0.00 1.16 0.92
42 INT231716 Binding of IL6 and DIP 1 0.24 1.55 0.87
43 INT342986 PTAFR Positive_regulation of Gene_expression of IL6 1 0.14 0.39 0.84
44 INT105435 TNF Positive_regulation of IL6 5 0.25 4.45 0.83
45 INT86430 IL6 Positive_regulation of Gene_expression of HP 1 0.15 3.61 0.83
46 INT195217 EGFL7 Negative_regulation of Gene_expression of IL6 1 0.06 1.14 0.83
47 INT342999 IL6 Positive_regulation of Gene_expression of HIST2H2AA3 1 0.00 0.4 0.83
48 INT117341 ADAM17 Positive_regulation of EGFR 1 0.16 3.56 0.82
49 INT306271 IL1A Positive_regulation of Gene_expression of IL6 1 0.30 0.85 0.8
50 INT127876 ACE Positive_regulation of Protein_catabolism of CALCA 1 0.28 0.63 0.75
51 INT178579 CNTN2 Positive_regulation of IL6 1 0.07 2.17 0.75
52 INT142847 IRF6 Positive_regulation of IL6 5 0.07 1.09 0.73
53 INT248271 IL6 Regulation of Gene_expression of Crp 3 0.27 1.7 0.73
54 INT172134 Binding of IL6 and IL15 2 0.01 1.18 0.72
55 INT236364 CD40LG Positive_regulation of Gene_expression of IL6 1 0.25 1.37 0.72
56 INT51005 PDYN Positive_regulation of IL6 1 0.08 0.84 0.72
57 INT77689 Binding of Ace and Tenc1 1 0.28 0.65 0.7
58 INT346267 Binding of HGF and IL6 1 0.04 0.96 0.7
59 INT278968 LEP Regulation of Gene_expression of IL6 1 0.29 1.11 0.69
60 INT391 Binding of Agt and Ace 2 0.33 1.5 0.68
61 INT203758 Binding of IL6 and TNF 3 0.26 2.03 0.67
62 INT278953 IL6 Regulation of Gene_expression of PTGER2 1 0.04 1.38 0.67
63 INT320152 IL6 Positive_regulation of IL1RN 2 0.23 2.59 0.66
64 INT285943 IL17A Positive_regulation of Localization of IL6 3 0.20 2.02 0.65
65 INT121812 IL6 Regulation of OPRM1 1 0.22 0.27 0.65
66 INT191494 IL6 Positive_regulation of Binding of CRP 1 0.02 1.65 0.65
67 INT64956 IRF6 Positive_regulation of Gene_expression of IL6 4 0.19 1.4 0.63
68 INT121188 Negative_regulation of KCNMA1 Positive_regulation of IL6 1 0.04 0.3 0.63
69 INT285939 IL6 Positive_regulation of TEP1 1 0.01 1.76 0.61
70 INT21607 ACE Positive_regulation of ANGPT2 1 0.03 0.13 0.61
71 INT169294 EGF Positive_regulation of Localization of IL6 1 0.18 0.13 0.61
72 INT327167 RETNLB Regulation of IL6 1 0.00 2.26 0.6
73 INT65014 SOS1 Positive_regulation of Gene_expression of IL6 1 0.45 0.42 0.6
74 INT181619 ACE Positive_regulation of KNG1 1 0.33 0.97 0.58
75 INT121813 IL6 Positive_regulation of OPRM1 1 0.28 0.28 0.58
76 INT231712 GAGE2C Regulation of Transcription of IL6 1 0.01 1.01 0.57
77 INT144035 IL6 Positive_regulation of STAT3 4 0.31 2.58 0.56
78 INT307016 IGKV1-17 Positive_regulation of Gene_expression of IL6 1 0.00 1.01 0.56
79 INT265463 CSPG4 Negative_regulation of Gene_expression of IL6 1 0.06 1.6 0.56
80 INT231711 GPR174 Regulation of Transcription of IL6 1 0.01 0.96 0.54
81 INT100597 Regulation of RPL21P132 Positive_regulation of IL6 1 0.01 0.45 0.53
82 INT285940 Binding of IL6 and IL17A 1 0.11 1.42 0.53
83 INT310532 IL6 Regulation of Regulation of TNF 1 0.34 0.73 0.52
84 INT310531 IL6 Regulation of Regulation of ADIPOQ 1 0.19 0.73 0.52
85 INT117203 Binding of IL1B and IL6 2 0.20 1.4 0.51
86 INT207396 IL6 Positive_regulation of Gene_expression of Tnfsf11 1 0.03 0.95 0.51
87 INT64720 Regulation of IL1B Positive_regulation of IL6 1 0.36 0.65 0.5
88 INT97801 Gm5564 Regulation of Gene_expression of IL6 1 0.00 0.07 0.5
89 INT195220 Binding of CPB2 and IL6 1 0.04 0.5 0.49
90 INT138153 Tgfb1 Regulation of IL6 1 0.01 0.29 0.49
91 INT100595 RPL21P132 Positive_regulation of IL6 1 0.01 0.43 0.49
92 INT61616 TNF Negative_regulation of Gene_expression of IL6 1 0.37 0.33 0.49
93 INT314756 IL6 Positive_regulation of Gene_expression of Crp 2 0.13 4.58 0.48
94 INT260858 IL6 Positive_regulation of Gene_expression of VEGFA 2 0.31 1.77 0.48
95 INT286352 IL6 Positive_regulation of Gene_expression of IL8 2 0.24 1.32 0.48
96 INT115186 IL6 Positive_regulation of Phosphorylation of STAT3 2 0.19 0.35 0.48
97 INT155921 PARP1 Positive_regulation of Gene_expression of IL6 1 0.49 0.44 0.48
98 INT150536 OPRM1 Positive_regulation of Positive_regulation of IL6 1 0.04 0.38 0.48
99 INT150537 OPRM1 Positive_regulation of Negative_regulation of IL6 1 0.04 0.38 0.48
100 INT132448 MIR3607 Negative_regulation of IL6 1 0.01 2.45 0.48
101 INT150539 OPRM1 Positive_regulation of IL6 1 0.04 0.38 0.48
102 INT135589 CSF2 Regulation of IL6 1 0.08 1.27 0.48
103 INT132792 IL4 Positive_regulation of IL6 4 0.28 1.81 0.47
104 INT189151 MTNR1B Positive_regulation of Gene_expression of IL6 1 0.01 0.35 0.47
105 INT231340 INCENP Regulation of Gene_expression of IL6 1 0.01 1.09 0.47
106 INT276207 Binding of Akt1 and Myo1f 1 0.11 0.05 0.47
107 INT138152 IL6 Positive_regulation of Transcription of Mmp2 1 0.00 0.23 0.46
108 INT138159 IL6 Positive_regulation of Gene_expression of Mmp3 1 0.00 0.23 0.46
109 INT37599 Ace Regulation of Localization of Insr 1 0.18 0 0.46
110 INT342633 ACE Regulation of Gene_expression of AGT 1 0.01 0.14 0.46
111 INT67528 PTGER2 Positive_regulation of Gene_expression of IL6 2 0.10 1.38 0.45
112 INT67527 MRXS5 Positive_regulation of Gene_expression of IL6 1 0.21 1.5 0.45
113 INT355568 MIF Positive_regulation of IL6 1 0.05 1.05 0.44
114 INT246023 IL6 Positive_regulation of SOCS2 1 0.18 0.99 0.43
115 INT188194 OSM Regulation of IL6 1 0.16 1.12 0.43
116 INT188211 IL6 Regulation of MAPK1 1 0.16 1.13 0.43
117 INT188207 LIF Regulation of IL6 1 0.17 1.12 0.43
118 INT169288 TRPV1 Positive_regulation of Localization of IL6 1 0.24 0 0.42
119 INT83913 Il1b Positive_regulation of Gene_expression of IL6 1 0.01 0.5 0.41
120 INT83916 Il1b Positive_regulation of IL6 1 0.02 0.5 0.41
121 INT100594 DCSTAMP Positive_regulation of Gene_expression of IL6 1 0.03 0.24 0.41
122 INT329803 TLR2 Positive_regulation of Positive_regulation of IL6 1 0.01 0.94 0.41
123 INT100598 PRNP Positive_regulation of Gene_expression of IL6 1 0.40 0.23 0.4
124 INT343919 Hspa1a Positive_regulation of Gene_expression of IL6 1 0.02 1.17 0.4
125 INT188336 IL6 Positive_regulation of Localization of POMC 1 0.01 0.83 0.4
126 INT294780 IL6 Positive_regulation of IL10 2 0.10 1.26 0.39
127 INT285746 IL6 Regulation of Localization of PRL 1 0.08 1.51 0.39
128 INT285749 IL6 Positive_regulation of Localization of PRL 1 0.08 1.51 0.39
129 INT114067 Ace Regulation of Insr 1 0.09 0.31 0.39
130 INT143747 Binding of IL6 and LEP 2 0.04 4.05 0.38
131 INT188427 IL6 Positive_regulation of Pdxp 1 0.00 0.84 0.38
132 INT267585 TNF Regulation of IL6 2 0.16 2.44 0.37
133 INT172135 Binding of IL2 and IL6 1 0.01 0.57 0.37
134 INT229222 Negative_regulation of ACE Negative_regulation of Protein_catabolism of KNG1 1 0.06 0.53 0.37
135 INT285935 IL6 Positive_regulation of Gene_expression of POU5F1 1 0.14 2.68 0.37
136 INT78854 APP Positive_regulation of Localization of IL6 1 0.14 0.79 0.37
137 INT292622 IL6 Positive_regulation of IL4 1 0.02 0.36 0.36
138 INT311264 IL6 Positive_regulation of Gene_expression of PPIAP10 1 0.30 0.98 0.36
139 INT286347 IL8 Positive_regulation of Gene_expression of IL6 1 0.11 0.7 0.36
140 INT179202 NLRP1 Regulation of Gene_expression of IL6 1 0.07 0.77 0.36
141 INT286350 IL6 Positive_regulation of Gene_expression of IRF6 1 0.04 0.71 0.36
142 INT334393 IL6 Positive_regulation of Tnf 1 0.16 1.41 0.35
143 INT334951 IL6 Positive_regulation of Regulation of IL1RN 1 0.23 1.11 0.35
144 INT334949 IL6 Regulation of Regulation of IL1RN 1 0.13 1.11 0.35
145 INT183786 IL6 Negative_regulation of INS 1 0.09 1.61 0.35
146 INT343912 Fgg Positive_regulation of Gene_expression of IL6 1 0.00 0.83 0.35
147 INT334950 IL6 Regulation of IL1RN 1 0.13 1.11 0.35
148 INT230786 Binding of AGT and ACE 4 0.15 2.53 0.34
149 INT172004 IL17A Positive_regulation of Gene_expression of IL6 2 0.14 1.35 0.34
150 INT188204 Negative_regulation of IL6 Positive_regulation of STAT3 1 0.28 0.54 0.34
151 INT231715 GAGE2C Regulation of Localization of IL6 1 0.01 0.58 0.33
152 INT231714 GPR174 Regulation of Localization of IL6 1 0.01 0.58 0.33
153 INT230852 ACE Regulation of KNG1 2 0.03 0.72 0.32
154 INT311266 RENBP Regulation of IL6 1 0.02 1.59 0.32
155 INT175330 IL6 Positive_regulation of Gene_expression of CYP19A1 1 0.01 0.97 0.32
156 INT312573 AMBP Negative_regulation of IL6 1 0.11 1.41 0.32
157 INT307014 LBR Positive_regulation of Gene_expression of IL6 1 0.01 0.58 0.32
158 INT312571 AMBP Negative_regulation of Positive_regulation of IL6 1 0.11 1.41 0.32
159 INT307008 MT1JP Positive_regulation of Gene_expression of IL6 1 0.02 0.27 0.32
160 INT102874 TNF Negative_regulation of Transcription of IL6 1 0.53 0.42 0.31
161 INT278942 LEP Regulation of IL6 1 0.29 0.61 0.31
162 INT102869 PTGER2 Negative_regulation of Transcription of IL6 1 0.17 0.42 0.31
163 INT304280 CCNE1 Positive_regulation of IL6 1 0.00 1.93 0.31
164 INT102872 IL1A Negative_regulation of Transcription of IL6 1 0.43 0.42 0.31
165 INT116594 Negative_regulation of PTGS2 Negative_regulation of Gene_expression of IL6 1 0.22 0.45 0.31
166 INT177901 Binding of IL6 and Wbc1 1 0.00 1.05 0.31
167 INT323855 IL6 Positive_regulation of Positive_regulation of TNF 1 0.04 1.03 0.31
168 INT315369 Binding of IL6 and Crp 1 0.10 2.09 0.3
169 INT278961 IL6 Regulation of Gene_expression of LEP 1 0.29 0.89 0.3
170 INT265826 Binding of ACE and SERPINE1 1 0.24 1.08 0.3
171 INT230745 Negative_regulation of Ace Negative_regulation of Icam1 1 0.05 1.22 0.29
172 INT67529 PTGDS Positive_regulation of Positive_regulation of IL6 1 0.30 0.69 0.29
173 INT200639 Ace Positive_regulation of Gene_expression of TGFB1 1 0.06 1.36 0.29
174 INT230342 IL6 Regulation of IL4 1 0.02 0.57 0.28
175 INT230333 IL6 Regulation of IL13 1 0.03 0.57 0.28
176 INT230339 IL6 Regulation of IL5 1 0.03 0.57 0.28
177 INT116595 CASP1 Positive_regulation of IL6 1 0.07 0.46 0.28
178 INT230335 IL6 Regulation of IL9 1 0.03 0.57 0.28
179 INT116593 CPOX Regulation of IL6 1 0.10 0.45 0.28
180 INT101510 PPARA Regulation of IL6 1 0.31 0.53 0.27
181 INT282647 IL6 Positive_regulation of Gene_expression of F3 1 0.00 1.89 0.27
182 INT101511 PPARA Regulation of Gene_expression of IL6 1 0.31 0.53 0.27
183 INT292571 Positive_regulation of F2RL1 Positive_regulation of Localization of IL6 1 0.07 0.8 0.27
184 INT163301 Binding of IFNA1 and IL6 2 0.04 2.95 0.26
185 INT132801 IL4 Positive_regulation of Localization of IL6 2 0.26 1.47 0.26
186 INT249831 Binding of CHI3L1 and IL6 1 0.30 2.81 0.26
187 INT299494 Binding of IL6 and IGKV2D-38 1 0.25 0.59 0.26
188 INT155529 IRF6 Regulation of Transcription of IL6 1 0.08 0.79 0.26
189 INT76081 Plg Positive_regulation of Gene_expression of IL6 1 0.03 0.18 0.26
190 INT123468 IL6 Regulation of CSF2 1 0.25 1.22 0.26
191 INT76082 Plg Regulation of Gene_expression of IL6 1 0.01 0.19 0.26
192 INT102621 IL6 Regulation of Gene_expression of CPOX 1 0.13 0.78 0.25
193 INT175321 IL6 Positive_regulation of Localization of Oxt 1 0.01 0.7 0.25
194 INT64726 Ace Negative_regulation of KNG1 1 0.01 0.26 0.25
195 INT278963 IL6 Regulation of Gene_expression of NOS2 1 0.12 0.41 0.25
196 INT64727 Ace Positive_regulation of KNG1 1 0.01 0.26 0.25
197 INT179166 TFPI Positive_regulation of Gene_expression of IL6 1 0.03 0.18 0.25
198 INT312569 IL6 Positive_regulation of Localization of ELANE 1 0.11 1.05 0.24
199 INT199971 IL6 Positive_regulation of ESR1 1 0.08 0.84 0.24
200 INT191500 ACE Positive_regulation of Localization of KNG1 1 0.10 0.17 0.24

Single Events

The table below shows the top 100 pain related interactions that have been reported for neutrophil mediated immunity. They are ordered first by their pain relevance and then by number of times they were reported in neutrophil mediated immunity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22
2 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38
3 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3
4 INT12082 Localization of IL6 365 0.81 241.78 105.78
5 INT1724 Negative_regulation of ACE 437 0.59 315.64 74.48
6 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87
7 INT9234 Negative_regulation of Gene_expression of IL6 171 0.59 101.61 53.15
8 INT9210 Regulation of IL6 166 0.62 125.61 49.95
9 INT9239 Regulation of Gene_expression of IL6 106 0.61 75.24 36.53
10 INT1179 Negative_regulation of Ace 157 0.59 67.03 30.46
11 INT50230 Positive_regulation of Localization of IL6 105 0.70 69.21 29.52
12 INT86437 Binding of IL6 154 0.48 121.22 29.3
13 INT51054 Negative_regulation of Localization of IL6 45 0.59 24.48 18.97
14 INT27670 Negative_regulation of Ace 122 0.57 79.21 18.08
15 INT61626 Transcription of IL6 73 0.72 42.04 17.86
16 INT20665 Gene_expression of ACE 87 0.78 51.71 14.19
17 INT12084 Regulation of Localization of IL6 36 0.61 20.32 12.34
18 INT11047 Positive_regulation of Positive_regulation of IL6 45 0.66 28.7 9.37
19 INT20664 Binding of ACE 60 0.48 35.27 9.16
20 INT13085 Positive_regulation of ACE 50 0.70 44.2 8.31
21 INT4021 Positive_regulation of PLA2G1B 35 0.70 23.27 8.2
22 INT389 Gene_expression of Ace 21 0.67 10.31 8.1
23 INT25958 Regulation of Ace 26 0.59 11.88 7.87
24 INT4022 Negative_regulation of PLA2G1B 30 0.59 10.41 7.58
25 INT1771 Positive_regulation of Ace 31 0.68 10.47 7.46
26 INT42038 Localization of ACE 26 0.80 8.88 7.06
27 INT130875 Gene_expression of ADAM17 13 0.78 15.46 6.41
28 INT64724 Positive_regulation of Transcription of IL6 26 0.69 13.63 5.96
29 INT64723 Regulation of Positive_regulation of IL6 13 0.61 12.59 5.19
30 INT26477 Regulation of ACE 26 0.45 16.31 4.33
31 INT29327 Positive_regulation of Ace 13 0.67 8.79 4.33
32 INT387 Regulation of Ace 18 0.45 5.24 4.24
33 INT1722 Protein_catabolism of ACE 10 0.88 2.61 3.76
34 INT90406 Gene_expression of IL6R 27 0.38 15.74 3.64
35 INT174816 Binding of IL6R 14 0.09 11.26 3.63
36 INT14837 Gene_expression of PLA2G1B 12 0.60 10.69 3.58
37 INT64725 Regulation of Transcription of IL6 9 0.45 7.96 3.49
38 INT43948 Localization of PLA2G1B 17 0.78 6.92 2.99
39 INT105783 Protein_catabolism of IL6 7 0.48 4.72 2.95
40 INT8652 Protein_catabolism of Ace 10 0.94 4.7 2.74
41 INT74695 Gene_expression of Ace 41 0.73 53.33 2.33
42 INT10558 Regulation of Regulation of IL6 6 0.45 4.94 2.33
43 INT42140 Gene_expression of Myo1f 7 0.19 2.45 2.27
44 INT58469 Negative_regulation of Positive_regulation of IL6 16 0.42 8.1 2.14
45 INT388 Positive_regulation of Gene_expression of Ace 4 0.42 1.04 2.13
46 INT45646 Protein_catabolism of Ace 5 0.98 3.14 1.95
47 INT43084 Binding of Ace 10 0.46 4.7 1.93
48 INT33096 Negative_regulation of Gene_expression of ACE 9 0.43 2.84 1.93
49 INT64959 Positive_regulation of Negative_regulation of IL6 5 0.42 5.16 1.86
50 INT117346 Positive_regulation of ADAM17 5 0.50 6.69 1.86
51 INT173939 Negative_regulation of IL6R 9 0.11 5.92 1.83
52 INT55606 Binding of Ace 14 0.37 10.73 1.82
53 INT22335 Regulation of Negative_regulation of ACE 10 0.44 7.01 1.77
54 INT130874 Negative_regulation of Gene_expression of ADAM17 3 0.43 5.03 1.76
55 INT42065 Phosphorylation of Myo1f 13 0.38 2.05 1.71
56 INT87062 Positive_regulation of Binding of IL6 10 0.49 11.8 1.42
57 INT61223 Positive_regulation of Negative_regulation of ACE 6 0.49 5.92 1.37
58 INT44145 Negative_regulation of Gene_expression of Ace 5 0.40 4.5 1.33
59 INT88948 Localization of Ace 9 0.69 9.18 1.11
60 INT10559 Negative_regulation of Regulation of IL6 4 0.37 1.76 1.1
61 INT42138 Binding of Myo1f 5 0.10 1.49 1.03
62 INT41729 Negative_regulation of Positive_regulation of PLA2G1B 3 0.43 2.7 1.02
63 INT132435 Negative_regulation of ADAM17 2 0.50 3.75 1.02
64 INT182516 Negative_regulation of Negative_regulation of ACE 9 0.42 6.84 0.99
65 INT152021 Regulation of Negative_regulation of IL6 3 0.32 1.38 0.98
66 INT91762 Positive_regulation of Gene_expression of PLA2G1B 3 0.17 3.45 0.97
67 INT64958 Negative_regulation of Transcription of IL6 6 0.50 3.58 0.92
68 INT115192 Phosphorylation of IL6 7 0.70 1.55 0.84
69 INT83995 Positive_regulation of Gene_expression of ACE 8 0.68 8.09 0.82
70 INT230803 Regulation of Negative_regulation of Ace 2 0.39 1.89 0.81
71 INT102311 Regulation of IL6R 4 0.12 2.37 0.74
72 INT276176 Negative_regulation of Myo1f 4 0.12 1.85 0.71
73 INT259902 Regulation of Gene_expression of ACE 3 0.45 1.87 0.7
74 INT4020 Regulation of PLA2G1B 2 0.61 0.19 0.64
75 INT72446 Negative_regulation of Binding of ACE 4 0.42 2.48 0.62
76 INT56045 Positive_regulation of Localization of ACE 3 0.69 1.38 0.6
77 INT200636 Regulation of Gene_expression of Ace 1 0.26 1.64 0.6
78 INT188433 Negative_regulation of Binding of IL6 6 0.42 2.03 0.56
79 INT138678 Transcription of ADAM17 1 0.69 4.9 0.56
80 INT22333 Regulation of Negative_regulation of Ace 3 0.45 0.72 0.52
81 INT36764 Localization of Ace 7 0.80 1.53 0.51
82 INT138676 Localization of ADAM17 4 0.73 4.91 0.5
83 INT42139 Regulation of Myo1f 3 0.14 0.64 0.49
84 INT188434 Positive_regulation of IL6R 2 0.02 2.17 0.49
85 INT43091 Positive_regulation of Negative_regulation of Ace 3 0.30 1.51 0.48
86 INT115189 Regulation of Phosphorylation of IL6 1 0.04 0 0.48
87 INT276175 Positive_regulation of Transcription of Myo1f 1 0.10 1.03 0.47
88 INT276194 Positive_regulation of Gene_expression of Myo1f 1 0.14 1.03 0.47
89 INT240020 Regulation of Binding of IL6 4 0.36 4.38 0.46
90 INT276190 Transcription of Myo1f 1 0.11 1.02 0.46
91 INT276191 Negative_regulation of Binding of Myo1f 1 0.09 0.05 0.46
92 INT171150 Negative_regulation of Binding of Ace 2 0.17 2.67 0.44
93 INT230517 Localization of Myo1f 2 0.15 1.38 0.44
94 INT44032 Regulation of Positive_regulation of Ace 1 0.38 0.1 0.43
95 INT35501 Positive_regulation of Myo1f 5 0.69 1.73 0.39
96 INT114063 Negative_regulation of Localization of Ace 1 0.29 0.31 0.39
97 INT60040 Negative_regulation of Negative_regulation of Ace 6 0.43 3.64 0.38
98 INT181635 Positive_regulation of Protein_catabolism of ACE 1 0.15 0.41 0.38
99 INT260859 Negative_regulation of Binding of IL6R 1 0.06 1.08 0.38
100 INT77686 Transcription of Ace 2 0.65 2.65 0.37
101 INT229626 Negative_regulation of Localization of ACE 3 0.41 2 0.36
102 INT267844 Positive_regulation of Gene_expression of Ace 10 0.57 15.35 0.35
103 INT66251 Negative_regulation of Phosphorylation of Myo1f 1 0.20 0 0.35
104 INT90405 Positive_regulation of Gene_expression of IL6R 3 0.03 1.85 0.31
105 INT96863 Transcription of ACE 3 0.69 0.38 0.29
106 INT173941 Negative_regulation of Gene_expression of IL6R 2 0.04 0.48 0.29
107 INT230864 Regulation of Binding of ACE 1 0.22 0.79 0.29
108 INT288846 Negative_regulation of Transcription of ACE 1 0.43 0 0.29
109 INT229358 Negative_regulation of Protein_catabolism of Ace 1 0.40 0.93 0.27
110 INT47070 Positive_regulation of Localization of Ace 2 0.32 0.55 0.26
111 INT123399 Positive_regulation of Positive_regulation of PLA2G1B 1 0.15 0.47 0.26
112 INT229357 Regulation of Binding of Ace 1 0.43 0.86 0.26
113 INT298665 Positive_regulation of Protein_catabolism of IL6 1 0.09 2.03 0.25
114 INT65003 Negative_regulation of Negative_regulation of Ace 5 0.37 3.45 0.23
115 INT276203 Negative_regulation of Gene_expression of Myo1f 1 0.09 0.38 0.23
116 INT173345 Phosphorylation of PLA2G1B 1 0.05 0 0.22
117 INT195576 Binding of Myo1f 6 0.06 2.79 0.21
118 INT320154 Phosphorylation of IL6R 1 0.04 1.13 0.21
119 INT307794 Negative_regulation of Gene_expression of Ace 7 0.48 5.95 0.2
120 INT74514 Binding of PLA2G1B 2 0.48 0.37 0.19
121 INT69192 Positive_regulation of Positive_regulation of Ace 1 0.02 0 0.19
122 INT262261 Negative_regulation of Gene_expression of PLA2G1B 1 0.05 1.07 0.18
123 INT108414 Negative_regulation of Regulation of ACE 1 0.43 0.67 0.17
124 INT138679 Regulation of ADAM17 1 0.19 1.13 0.16
125 INT44051 Positive_regulation of Protein_catabolism of Ace 1 0.41 0 0.16
126 INT138680 Binding of ADAM17 1 0.36 1.42 0.16
127 INT276193 Regulation of Negative_regulation of Myo1f 1 0.09 0.38 0.14
128 INT59791 Positive_regulation of Negative_regulation of Ace 3 0.49 0.57 0.13
129 INT188222 Positive_regulation of Regulation of IL6 2 0.29 0.51 0.13
130 INT298669 Negative_regulation of Protein_catabolism of IL6 1 0.08 1.02 0.13
131 INT249970 Transcription of Ace 3 0.36 1.87 0.12
132 INT43092 Negative_regulation of Binding of Ace 1 0.31 0 0.12
133 INT79993 Positive_regulation of Positive_regulation of ACE 2 0.49 0.78 0.1
134 INT138677 Negative_regulation of Transcription of ADAM17 1 0.42 1.18 0.1
135 INT340501 Regulation of Transcription of Ace 1 0.10 0.84 0.1
136 INT266664 Positive_regulation of Localization of PLA2G1B 1 0.12 0.32 0.08
137 INT298670 Regulation of Gene_expression of IL6R 1 0.01 0.43 0.07
138 INT340500 Negative_regulation of Transcription of Ace 1 0.10 0.78 0.07
139 INT249971 Positive_regulation of Transcription of Ace 1 0.35 0.47 0.06
140 INT128209 Positive_regulation of Regulation of Ace 1 0.42 0.4 0.06
141 INT42326 Negative_regulation of Regulation of Ace 1 0.15 0 0.05
142 INT230809 Positive_regulation of Localization of Ace 1 0.44 0.38 0.05
143 INT265312 Gene_expression of Myo1f 3 0.10 1.44 0.04
144 INT102927 Negative_regulation of Localization of Ace 3 0.58 1 0.03
145 INT195575 Localization of Myo1f 2 0.12 0.28 0.03
146 INT272938 Negative_regulation of Myo1f 1 0.03 1.06 0.03
147 INT303355 Positive_regulation of Localization of Myo1f 1 0.10 0.22 0
148 INT303375 Positive_regulation of Myo1f 1 0.08 0.22 0
149 INT270742 Negative_regulation of Phosphorylation of ACE 1 0.40 0.65 0
150 INT292413 Negative_regulation of Binding of Myo1f 1 0.00 0.88 0
151 INT353415 Phosphorylation of Myo1f 1 0.08 0.61 0
152 INT353421 Positive_regulation of Phosphorylation of Myo1f 1 0.05 0.5 0
153 INT270740 Phosphorylation of ACE 1 0.76 0.65 0
154 INT303350 Regulation of Myo1f 1 0.09 0.26 0
155 INT316367 Negative_regulation of Transcription of Ace 1 0.40 0.22 0
156 INT287856 Positive_regulation of Positive_regulation of Myo1f 1 0.03 0.11 0
157 INT303365 Protein_catabolism of Myo1f 1 0.10 0.29 0
158 INT307796 Positive_regulation of Positive_regulation of Ace 1 0.39 1.33 0
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