GO:0002456

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Name T cell mediated immunity
Categary Process
Go Slim No
Go Link GO:0002456
Unique Molecular Interactions 97
Total Molecular Interactions 128
Total Single Events 1458
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for T cell mediated immunity. They are ordered first by their pain relevance and then by number of times they were reported for T cell mediated immunity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT117971 Cd8a Negative_regulation of Positive_regulation of Ephb1 1 0.02 0.98 0.79
2 INT205120 Binding of CD4 and CD8A 3 0.15 2.83 0.72
3 INT209956 Binding of CD8A and RDBP 1 0.01 0.3 0.7
4 INT330522 Binding of CD8A and TNFSF10 1 0.17 1.24 0.48
5 INT148611 Binding of CD8A and Cr2 1 0.02 0.81 0.44
6 INT292634 IL4 Positive_regulation of Gene_expression of FOXP3 1 0.10 0.42 0.43
7 INT330519 Binding of CD8A and DICER1 1 0.08 0.99 0.38
8 INT330516 Binding of CD8A and CCR6 1 0.07 0.99 0.38
9 INT330517 Binding of CD8A and HLA-DRB4 1 0.08 0.99 0.38
10 INT27029 HERPUD1 Regulation of Gene_expression of CD8A 1 0.41 0 0.34
11 INT27035 HERPUD1 Regulation of CD8A 1 0.18 0 0.34
12 INT211308 Binding of Cd4 and Cd8a 3 0.19 0.3 0.31
13 INT260433 Dbi Positive_regulation of Cd8a 1 0.00 0.13 0.3
14 INT260434 Binding of Cd8a and Mx1 1 0.00 1.52 0.29
15 INT141882 Binding of CD8A and HLA-A 1 0.32 0.9 0.29
16 INT349021 Binding of Cd8a and Cd4 1 0.10 0.58 0.26
17 INT63195 INS Positive_regulation of CD8A 1 0.19 0.3 0.23
18 INT63202 POMC Positive_regulation of CD8A 1 0.30 0.3 0.23
19 INT63201 PTH Positive_regulation of CD8A 1 0.45 0.29 0.22
20 INT330520 Positive_regulation of Binding of CD8A and TNFSF10 1 0.19 0.62 0.21
21 INT252817 Binding of CD8A and IL12A 1 0.02 1.36 0.19
22 INT353298 IFNA1 Positive_regulation of CD8A 1 0.04 0.75 0.19
23 INT286965 Binding of STAT3 and FOXP3 1 0.27 1.84 0.19
24 INT226380 Gene_expression of IL15 Negative_regulation of Positive_regulation of CD8A 1 0.02 1.59 0.18
25 INT350149 SH2B3 Regulation of CD8A 1 0.13 0.86 0.17
26 INT302553 Binding of CD8A and MID1 1 0.01 0.38 0.17
27 INT310937 Binding of CD8A and COPD 1 0.16 1.21 0.16
28 INT296081 Binding of FOXP3 and Gtf3a 1 0.00 1.16 0.16
29 INT296030 Binding of NFKB1 and FOXP3 1 0.17 1.18 0.16
30 INT249685 Binding of CD8A and GRDX 1 0.02 0.46 0.16
31 INT316052 Notch1 Regulation of Binding of Cd8a 1 0.01 0.86 0.15
32 INT316050 Binding of Notch1 and Regulation of Binding of Cd8a 1 0.01 0.86 0.15
33 INT296082 Binding of Rel and FOXP3 1 0.35 1.14 0.15
34 INT98565 HLA-B Positive_regulation of Cd8a 1 0.03 0.63 0.14
35 INT248951 Binding of Cd8a and Klrd1 1 0.34 0.41 0.13
36 INT316058 Ps Regulation of Binding of Cd8a 1 0.02 0.86 0.13
37 INT211313 Binding of Cd3e and Cd8a 1 0.02 0.19 0.13
38 INT181841 Binding of CD8A and PHB2 1 0.01 0.75 0.13
39 INT181844 Binding of CD8A and HLA-B 1 0.14 1.82 0.12
40 INT188360 Binding of Cd28 and Positive_regulation of Localization of Cd8a 1 0.09 0.18 0.11
41 INT284552 Binding of Cd8a and Mthfd1 2 0.03 1.32 0.1
42 INT286969 IL2 Regulation of Gene_expression of FOXP3 1 0.04 1.05 0.1
43 INT181845 Binding of CD8A and IFN1@ 2 0.13 0.65 0.09
44 INT333095 Localization of IL2 Negative_regulation of Negative_regulation of CD8A 1 0.10 0.8 0.09
45 INT163664 Binding of CD8A and KRT20 1 0.27 0.5 0.09
46 INT333121 Pol Positive_regulation of CD8A 1 0.00 0.08 0.09
47 INT333097 ERVW-1 Positive_regulation of CD8A 1 0.02 0.08 0.08
48 INT296039 Binding of FOXP3 and IL17RB 1 0.01 0.63 0.08
49 INT296034 FOXP3 Negative_regulation of Gene_expression of IL7R 1 0.10 0.63 0.08
50 INT210288 Binding of CD8A and ELAVL4 1 0.27 1.21 0.07
51 INT350708 Foxp3 Regulation of Socs1 1 0.08 0.21 0.07
52 INT274231 Fasl Positive_regulation of Gene_expression of Cd8a 1 0.03 1.01 0.07
53 INT248944 Positive_regulation of Binding of Cd8a and Klrd1 1 0.36 0 0.07
54 INT333098 Binding of CD8A and IL2 1 0.01 0.17 0.07
55 INT335712 Binding of FASLG and CD8A 1 0.18 0.9 0.06
56 INT335713 Binding of FAS and CD8A 1 0.32 0.9 0.06
57 INT248946 Binding of Cd8a and Klrc1 1 0.22 0.13 0.06
58 INT228744 Rae1 Negative_regulation of Gene_expression of Cd8a 1 0.02 0.31 0.05
59 INT228745 Hspa9 Negative_regulation of Gene_expression of Cd8a 1 0.03 0.31 0.05
60 INT333090 Localization of IFN1@ Negative_regulation of Negative_regulation of CD8A 1 0.10 0.4 0.05
61 INT293353 Binding of CD8A and Cd3e 1 0.01 0.07 0.04
62 INT286967 Positive_regulation of STAT3 Regulation of Gene_expression of FOXP3 1 0.35 0.44 0.04
63 INT350704 Foxp3 Negative_regulation of Gene_expression of Mir142 1 0.02 0.13 0.04
64 INT350696 Mir31 Regulation of Gene_expression of Foxp3 1 0.04 0 0.03
65 INT311870 Positive_regulation of Binding of Cd8a and Mthfd1 1 0.00 0.32 0.03
66 INT236235 HLA-A Positive_regulation of CD8A 1 0.01 1 0.03
67 INT309836 Binding of Cd8a and Dmp1 1 0.00 0.7 0
68 INT193696 Binding of CD8A and Trav6-3 1 0.00 0.85 0
69 INT236246 Binding of CD8A and Birc5 1 0.04 1.34 0
70 INT227250 Rtl1 Positive_regulation of CD8A 1 0.20 0.4 0
71 INT349220 Binding of CASP3 and CD8A 1 0.00 0.18 0
72 INT335240 Binding of CD8A and PMEL 1 0.28 0.81 0
73 INT294883 Binding of CD8A and IGHG3 1 0.03 0 0
74 INT227218 Binding of JAG1 and CD8A 1 0.05 0.5 0
75 INT341485 Binding of CD8A and GZMB 1 0.01 0.7 0
76 INT341486 Positive_regulation of TLR2 Positive_regulation of CD8A 1 0.11 0.3 0
77 INT355306 Binding of Cd5 and Cd8a 1 0.04 1.99 0
78 INT258923 Binding of CD8A and Atp8a1 1 0.23 0.07 0
79 INT293974 POMC Positive_regulation of Cd8a 1 0.22 1.27 0
80 INT350707 Uts2r Negative_regulation of Gene_expression of Foxp3 1 0.03 0 0
81 INT248947 Binding of Cd8a and Tgfb1 1 0.05 0.16 0
82 INT333093 AD5 Regulation of CD8A 1 0.00 0.25 0
83 INT293976 POMC Positive_regulation of Gene_expression of Cd8a 1 0.22 0.35 0
84 INT354833 Csf2 Positive_regulation of Cd8a 1 0.01 0.98 0
85 INT248952 Klrd1 Regulation of Cd8a 1 0.32 0.26 0
86 INT240410 Gene_expression of CD69 Positive_regulation of CD8A 1 0.10 0 0
87 INT301677 Binding of APC and CD8A 1 0.03 1.48 0
88 INT309835 Binding of Cd8a and Ahnak 1 0.00 0.65 0
89 INT341488 Binding of CD8A and TLR2 1 0.08 0.31 0
90 INT256385 Foxp3 Positive_regulation of Cd4 1 0.32 0.15 0
91 INT343500 Binding of CD8A and ERVW-1 1 0.11 0.13 0
92 INT210287 Binding of CD8A and GOPC 1 0.07 0.87 0
93 INT258907 Binding of CD8A and HLA-G 1 0.05 0.07 0
94 INT301676 Binding of CD8A and HLA-E 1 0.02 2.24 0
95 INT355311 Positive_regulation of Binding of Cd5 and Cd8a 1 0.06 2 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for T cell mediated immunity. They are ordered first by their pain relevance and then by number of times they were reported in T cell mediated immunity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT19856 Gene_expression of CD8A 240 0.75 147.86 26.39
2 INT18311 Positive_regulation of CD8A 145 0.69 113.48 19.44
3 INT10016 Negative_regulation of CD8A 81 0.42 56.68 13.15
4 INT10019 Binding of CD8A 57 0.36 31.49 10.08
5 INT155944 Gene_expression of Foxp3 66 0.66 24.37 9.12
6 INT20371 Gene_expression of Cd8a 125 0.60 67.59 8.97
7 INT169015 Gene_expression of FOXP3 50 0.60 33.18 8.4
8 INT18909 Positive_regulation of Cd8a 92 0.60 56.55 7.35
9 INT56149 Localization of CD8A 56 0.74 30.41 5.75
10 INT16405 Regulation of CD8A 38 0.45 19.04 5.31
11 INT140337 Negative_regulation of Cd8a 42 0.50 25.4 3.66
12 INT64030 Gene_expression of Cd8a 15 0.56 4.8 3.63
13 INT188344 Positive_regulation of Gene_expression of Foxp3 10 0.36 5.97 2.56
14 INT20373 Localization of Cd8a 28 0.64 8.22 2.07
15 INT221431 Negative_regulation of FOXP3 8 0.40 9.92 1.98
16 INT58691 Positive_regulation of Gene_expression of CD8A 26 0.50 15.19 1.97
17 INT167035 Regulation of Cd8a 25 0.41 16.78 1.9
18 INT36018 Negative_regulation of Gene_expression of CD8A 12 0.42 6.66 1.85
19 INT97621 Negative_regulation of Cd8a 3 0.24 3.08 1.77
20 INT221426 Positive_regulation of Gene_expression of FOXP3 9 0.48 5.98 1.72
21 INT167872 Negative_regulation of Gene_expression of Foxp3 8 0.50 4.14 1.46
22 INT83330 Regulation of Gene_expression of Cd8a 1 0.23 0.88 1.16
23 INT229562 Negative_regulation of Foxp3 6 0.36 3.7 1.14
24 INT140919 Binding of Cd8a 2 0.12 1.4 1.07
25 INT58692 Regulation of Gene_expression of CD8A 11 0.42 10.16 1
26 INT56151 Positive_regulation of Positive_regulation of CD8A 11 0.34 9.74 0.94
27 INT178183 Binding of Cd8a 16 0.32 7.8 0.85
28 INT221427 Positive_regulation of FOXP3 6 0.45 2.74 0.83
29 INT157492 Transcription of Foxp3 4 0.61 1.69 0.81
30 INT178175 Positive_regulation of Gene_expression of Cd8a 17 0.43 13.05 0.78
31 INT150251 Transcription of FOXP3 7 0.61 0.43 0.76
32 INT179062 Positive_regulation of Positive_regulation of Cd8a 8 0.43 5.68 0.74
33 INT158295 Transcription of CD8A 11 0.53 4.02 0.7
34 INT221428 Negative_regulation of Negative_regulation of FOXP3 1 0.35 1.97 0.7
35 INT103124 Regulation of Cd8a 3 0.23 1.65 0.68
36 INT297286 Positive_regulation of Foxp3 7 0.58 3.05 0.63
37 INT154772 Positive_regulation of Localization of CD8A 7 0.24 3.58 0.63
38 INT191825 Regulation of Positive_regulation of CD8A 3 0.12 2.5 0.62
39 INT166644 Positive_regulation of Cd8a 6 0.14 3.04 0.59
40 INT243665 Positive_regulation of Gene_expression of Cd8a 2 0.12 1.91 0.51
41 INT176891 Negative_regulation of Localization of CD8A 4 0.22 2.58 0.49
42 INT157490 Regulation of Gene_expression of Foxp3 5 0.37 2.4 0.47
43 INT188345 Regulation of Foxp3 3 0.18 1.59 0.42
44 INT260115 Regulation of FOXP3 3 0.29 0.75 0.34
45 INT260120 Regulation of Gene_expression of FOXP3 4 0.31 2.74 0.29
46 INT253647 Phosphorylation of CD8A 3 0.25 0.7 0.29
47 INT219213 Regulation of Binding of CD8A 1 0.30 0 0.27
48 INT171130 Protein_catabolism of CD8A 1 0.83 0.47 0.27
49 INT181133 Negative_regulation of Gene_expression of Cd8a 7 0.37 2.65 0.25
50 INT28247 Negative_regulation of Positive_regulation of CD8A 3 0.14 2.84 0.24
51 INT226799 Negative_regulation of Localization of Cd8a 2 0.11 1.1 0.21
52 INT188346 Binding of Foxp3 1 0.27 0.4 0.18
53 INT276372 Negative_regulation of Gene_expression of FOXP3 2 0.38 1.49 0.16
54 INT150253 Positive_regulation of Transcription of FOXP3 2 0.39 0 0.15
55 INT335788 Localization of FOXP3 1 0.34 0.42 0.15
56 INT265419 Negative_regulation of Binding of CD8A 2 0.08 0.9 0.14
57 INT335812 Regulation of Transcription of FOXP3 1 0.21 0.34 0.14
58 INT286970 Binding of FOXP3 1 0.24 1.04 0.13
59 INT276923 Localization of Foxp3 1 0.38 0.52 0.12
60 INT237986 Regulation of Gene_expression of Cd8a 3 0.24 0.83 0.1
61 INT228096 Regulation of Positive_regulation of Cd8a 2 0.39 0.43 0.09
62 INT286971 Positive_regulation of Positive_regulation of FOXP3 1 0.32 0.57 0.09
63 INT210118 Negative_regulation of Positive_regulation of Cd8a 2 0.38 1.34 0.08
64 INT174554 Positive_regulation of Negative_regulation of Cd8a 2 0.20 1.53 0.07
65 INT185227 Positive_regulation of Localization of Cd8a 2 0.19 1.77 0.07
66 INT205023 Negative_regulation of Gene_expression of Cd8a 1 0.11 0.3 0.07
67 INT296074 Regulation of Positive_regulation of FOXP3 1 0.18 0.28 0.06
68 INT260113 Positive_regulation of Regulation of FOXP3 1 0.32 0.15 0.04
69 INT205019 Negative_regulation of Positive_regulation of Cd8a 1 0.11 0.83 0.04
70 INT333755 Negative_regulation of Positive_regulation of Foxp3 1 0.49 0.18 0.03
71 INT185231 Transcription of Cd8a 5 0.47 2.79 0
72 INT202603 Positive_regulation of Regulation of CD8A 2 0.16 0.27 0
73 INT282776 Regulation of Localization of CD8A 2 0.42 0.65 0
74 INT157493 Positive_regulation of Transcription of Foxp3 1 0.59 0.06 0
75 INT323133 Negative_regulation of Phosphorylation of CD8A 1 0.04 0.27 0
76 INT185229 Negative_regulation of Binding of Cd8a 1 0.16 0.9 0
77 INT314947 Negative_regulation of Transcription of Cd8a 1 0.29 0.15 0
78 INT256382 Regulation of Localization of Cd8a 1 0.20 0.43 0
79 INT247953 Regulation of Regulation of Cd8a 1 0.32 1.93 0
80 INT288670 Negative_regulation of Negative_regulation of CD8A 1 0.30 0.5 0
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