GO:0002523

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Name leukocyte migration involved in inflammatory response
Categary Process
Go Slim No
Go Link GO:0002523
Unique Molecular Interactions 58
Total Molecular Interactions 73
Total Single Events 625
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for leukocyte migration involved in inflammatory response. They are ordered first by their pain relevance and then by number of times they were reported for leukocyte migration involved in inflammatory response. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT329962 Binding of C5 and HEPACAM 1 0.03 2.25 1.06
2 INT103796 IL1B Positive_regulation of Gene_expression of SELE 2 0.08 1 0.98
3 INT252858 C5 Negative_regulation of Positive_regulation of Trpa1 1 0.02 0.78 0.74
4 INT176476 TNF Positive_regulation of Gene_expression of SELE 1 0.04 0.57 0.63
5 INT139834 NFKB1 Regulation of Gene_expression of SELE 1 0.18 0.49 0.5
6 INT139835 NFKB1 Regulation of SELE 1 0.41 0.49 0.5
7 INT329960 Binding of C5 and TRAF1 1 0.32 1.04 0.42
8 INT329958 Binding of C5 and STAT4 1 0.33 0.93 0.41
9 INT324802 Binding of Cd24a and Siglecg 1 0.03 1.34 0.4
10 INT203140 Binding of C5ar1 and C5 1 0.39 0.81 0.38
11 INT320694 C5 Regulation of Gene_expression of Il2 1 0.03 2.15 0.34
12 INT320692 C5 Regulation of Gene_expression of Il12a 1 0.03 2.15 0.34
13 INT320693 C5 Regulation of Gene_expression of Il6 1 0.04 2.15 0.34
14 INT320696 C5 Regulation of Gene_expression of TNF 1 0.34 2.15 0.34
15 INT320691 C5 Regulation of Gene_expression of Il1 1 0.06 2.15 0.34
16 INT182126 IRF6 Positive_regulation of Gene_expression of SELE 1 0.03 0.86 0.34
17 INT332013 Hc Regulation of Binding of C3ar1 1 0.12 1.11 0.21
18 INT332016 C3ar1 Regulation of Binding of Hc 1 0.12 1.11 0.21
19 INT309661 C5 Positive_regulation of Phosphorylation of Akt1 1 0.51 0.45 0.21
20 INT324824 Positive_regulation of Binding of Cd24a and Siglecg 1 0.03 0.68 0.2
21 INT64964 Binding of Alb and Cd24 1 0.02 0.2 0.2
22 INT324822 Binding of Cd24a and Hsp90aa1 1 0.10 0.71 0.19
23 INT324797 Binding of Cd24a and Hmgb1 1 0.19 0.66 0.19
24 INT99013 Binding of Itgb2 and Selp 1 0.16 1.36 0.18
25 INT99011 Regulation of Binding of Itgb2 and Selp 1 0.19 1.37 0.18
26 INT273714 Positive_regulation of Binding of Icam1 and Itgb2 1 0.17 1.46 0.15
27 INT273717 Binding of Icam1 and Itgb2 1 0.17 1.45 0.15
28 INT173406 Binding of ITGAL and Itgb2 1 0.02 0.41 0.13
29 INT289404 Mthfd1 Positive_regulation of Hc 1 0.04 0.58 0.12
30 INT309662 C5 Positive_regulation of Akt1 1 0.30 0.43 0.11
31 INT210899 Binding of SELE and IGHD1-14 1 0.39 3.31 0.11
32 INT64966 Binding of AGFG1 and Cd24 1 0.00 0.1 0.1
33 INT294431 IL18 Positive_regulation of Gene_expression of SELE 1 0.06 0.98 0.1
34 INT41832 Binding of ALB and C5 1 0.41 0.07 0.08
35 INT173408 GPER Regulation of Itgb2 1 0.01 0.23 0.08
36 INT279502 Binding of C2 and Hc 1 0.01 0.2 0.07
37 INT230853 Binding of SELE and VWF 1 0.06 1.3 0.07
38 INT346149 ADM Positive_regulation of Gene_expression of SELE 1 0.22 0.85 0.07
39 INT218511 Cfb Positive_regulation of C5 1 0.01 0.29 0.06
40 INT299703 ECB2 Negative_regulation of Binding of C5 1 0.00 0.39 0.06
41 INT313500 Binding of SELE and SNRNP70 1 0.01 0.55 0.04
42 INT320991 C5AR1 Regulation of C5 1 0.05 0 0.03
43 INT321412 ABCC8 Positive_regulation of Gene_expression of SELE 1 0.00 1.18 0.03
44 INT273719 Binding of Itgb2 and Trav6-3 1 0.07 0.47 0.03
45 INT279698 Hc Regulation of Trpv1 1 0.01 0 0
46 INT299705 C5 Positive_regulation of Positive_regulation of C5AR1 1 0.03 0.1 0
47 INT289301 Binding of CD59 and Cd24a 1 0.02 1.06 0
48 INT210898 IGHD1-14 Regulation of SELE 1 0.22 1.51 0
49 INT218505 Binding of C5 and Cfb 1 0.01 0.29 0
50 INT279695 Hc Negative_regulation of Car2 1 0.02 0 0
51 INT279696 Hc Negative_regulation of Trpv1 1 0.01 0 0
52 INT218532 Binding of C5 and LCN1 1 0.06 0.49 0
53 INT279694 Hc Negative_regulation of Catsper1 1 0.05 0 0
54 INT113099 L1cam Negative_regulation of Aoc3 1 0.25 0.18 0
55 INT273720 Binding of Cd28 and Itgb2 1 0.10 0 0
56 INT234306 Binding of Gria4 and Hc 1 0.01 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for leukocyte migration involved in inflammatory response. They are ordered first by their pain relevance and then by number of times they were reported in leukocyte migration involved in inflammatory response. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT49196 Gene_expression of SELE 105 0.78 107.29 22.92
2 INT62525 Positive_regulation of SELE 38 0.70 46 5.25
3 INT62832 Negative_regulation of Gene_expression of SELE 16 0.49 10.6 5.12
4 INT62822 Positive_regulation of Gene_expression of SELE 22 0.66 28.04 4.97
5 INT62526 Negative_regulation of SELE 17 0.51 15.24 4.19
6 INT6507 Binding of C5 23 0.48 15.35 3.91
7 INT69904 Binding of Hc 11 0.35 7.79 3.69
8 INT107074 Gene_expression of C5 14 0.75 9.87 3.64
9 INT135963 Negative_regulation of Hc 19 0.42 12.36 3.63
10 INT111482 Gene_expression of Cd24a 23 0.72 13.74 3.37
11 INT145774 Positive_regulation of C5 7 0.67 4.88 2.79
12 INT64147 Gene_expression of C5 15 0.60 16.8 2.78
13 INT121683 Gene_expression of Hc 23 0.75 7.15 2.7
14 INT51461 Gene_expression of Itgb2 7 0.75 5.48 2.2
15 INT135961 Positive_regulation of Hc 8 0.67 3.67 1.87
16 INT26426 Localization of C5 5 0.78 3.87 1.61
17 INT212790 Regulation of C5 6 0.24 6.04 1.59
18 INT100909 Negative_regulation of Gene_expression of Itgb2 2 0.41 1.79 1.22
19 INT107942 Positive_regulation of C5 9 0.50 6.86 1.19
20 INT145773 Positive_regulation of Localization of C5 1 0.49 1.15 1.06
21 INT100911 Positive_regulation of Itgb2 1 0.51 1.62 0.99
22 INT272918 Positive_regulation of Positive_regulation of SELE 2 0.03 2.24 0.96
23 INT178803 Gene_expression of Itgb2 10 0.44 5.13 0.87
24 INT112783 Regulation of Gene_expression of SELE 6 0.40 6.82 0.87
25 INT35292 Negative_regulation of C5 7 0.43 5.3 0.86
26 INT184351 Localization of Hc 2 0.20 2.33 0.83
27 INT269693 Regulation of Negative_regulation of Hc 1 0.00 0.09 0.83
28 INT329967 Positive_regulation of Gene_expression of C5 1 0.42 1.63 0.81
29 INT340843 Binding of Cd24a 1 0.02 0.24 0.8
30 INT49197 Binding of SELE 7 0.41 7.95 0.74
31 INT100910 Regulation of Positive_regulation of Itgb2 1 0.20 0.53 0.72
32 INT51459 Positive_regulation of Gene_expression of Itgb2 2 0.37 1.92 0.7
33 INT62831 Negative_regulation of Positive_regulation of SELE 3 0.36 1.63 0.69
34 INT121684 Positive_regulation of Gene_expression of Hc 3 0.67 1.56 0.69
35 INT161201 Localization of C5 2 0.75 0.93 0.69
36 INT252856 Positive_regulation of Positive_regulation of C5 1 0.02 0.95 0.67
37 INT157225 Negative_regulation of Gene_expression of Hc 2 0.12 1.12 0.66
38 INT187738 Localization of SELE 4 0.64 8.13 0.64
39 INT203146 Protein_catabolism of C5 1 0.64 1.62 0.64
40 INT166437 Binding of C5 4 0.36 3.28 0.63
41 INT184367 Protein_catabolism of Hc 4 0.26 2.66 0.6
42 INT243055 Gene_expression of Aoc3 1 0.20 1.54 0.57
43 INT340842 Regulation of Gene_expression of Cd24a 1 0.42 0.08 0.53
44 INT85081 Protein_catabolism of C5 5 0.19 1.34 0.5
45 INT64961 Binding of Cd24 4 0.15 0.64 0.5
46 INT326696 Regulation of Cd24a 2 0.44 0 0.48
47 INT51462 Regulation of Gene_expression of Itgb2 2 0.34 0.79 0.47
48 INT143548 Binding of Itgb2 1 0.35 0 0.44
49 INT118202 Negative_regulation of Itgb2 1 0.41 1.05 0.42
50 INT171773 Regulation of SELE 7 0.23 10.3 0.4
51 INT27059 Negative_regulation of C5 2 0.42 1.87 0.35
52 INT207775 Negative_regulation of Gene_expression of C5 4 0.42 2.08 0.33
53 INT99005 Positive_regulation of Itgb2 8 0.39 6.36 0.27
54 INT108566 Negative_regulation of Aoc3 2 0.54 0.57 0.27
55 INT98996 Regulation of Itgb2 2 0.25 2.09 0.27
56 INT187737 Phosphorylation of SELE 2 0.69 2.02 0.27
57 INT275540 Regulation of Negative_regulation of SELE 1 0.01 1.13 0.22
58 INT135960 Regulation of Hc 2 0.44 1.28 0.21
59 INT238246 Regulation of Gene_expression of C5 1 0.12 0 0.19
60 INT212788 Regulation of Regulation of C5 1 0.24 0.48 0.18
61 INT212789 Negative_regulation of Gene_expression of C5 2 0.38 1.04 0.17
62 INT115522 Regulation of Itgb2 3 0.19 0.5 0.15
63 INT344816 Regulation of Gene_expression of Itgb2 1 0.07 0.56 0.15
64 INT125712 Regulation of C5 1 0.07 0.07 0.15
65 INT309647 Regulation of Positive_regulation of C5 1 0.44 0.46 0.15
66 INT196112 Transcription of Hc 1 0.17 0.08 0.11
67 INT273704 Binding of Itgb2 3 0.20 2.59 0.1
68 INT210912 Transcription of SELE 1 0.59 1.03 0.1
69 INT254742 Gene_expression of Cd24 1 0.11 0.46 0.09
70 INT254732 Localization of Cd24 1 0.12 0.46 0.09
71 INT355318 Positive_regulation of Gene_expression of Cd24a 1 0.47 1.17 0.09
72 INT273698 Positive_regulation of Positive_regulation of Itgb2 1 0.39 0.22 0.08
73 INT254740 Negative_regulation of Cd24 1 0.07 0.08 0.07
74 INT210913 Positive_regulation of Localization of SELE 1 0.43 1.58 0.04
75 INT313544 Regulation of Positive_regulation of SELE 1 0.08 0.52 0.04
76 INT326709 Negative_regulation of Gene_expression of Cd24a 3 0.40 0.86 0
77 INT200854 Transcription of Cd24a 2 0.66 0.4 0
78 INT135962 Regulation of Gene_expression of Hc 2 0.60 0.71 0
79 INT299681 Negative_regulation of Positive_regulation of C5 1 0.12 0.17 0
80 INT279442 Negative_regulation of Protein_catabolism of Hc 1 0.04 0 0
81 INT299674 Regulation of Gene_expression of C5 1 0.13 0.18 0
82 INT355323 Negative_regulation of Cd24a 1 0.40 0.08 0
83 INT218474 Negative_regulation of Binding of C5 1 0.06 0.53 0
84 INT218534 Negative_regulation of Binding of C5 1 0.41 0.23 0
85 INT255262 Transcription of C5 1 0.42 3 0
86 INT279469 Negative_regulation of Binding of Hc 1 0.05 0 0
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