GO:0002551

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Name mast cell chemotaxis
Categary Process
Go Slim No
Go Link GO:0002551
Unique Molecular Interactions 87
Total Molecular Interactions 121
Total Single Events 1073
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for mast cell chemotaxis. They are ordered first by their pain relevance and then by number of times they were reported for mast cell chemotaxis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT318996 Binding of CCR3 and CCL5 1 0.07 3.39 2.9
2 INT189490 Binding of Ccr3 and Ccl5 1 0.33 8.54 2.6
3 INT116730 Rac1 Regulation of Localization of Calca 1 0.13 1.32 1.19
4 INT128655 ITIH4 Regulation of Gene_expression of CCR3 1 0.36 1.45 0.92
5 INT53152 Rac1 Regulation of Scg2 1 0.03 0 0.9
6 INT53155 Rac1 Positive_regulation of Gene_expression of Calca 1 0.06 0 0.89
7 INT43662 Negative_regulation of Binding of Chrna7 and Rac1 1 0.01 0 0.73
8 INT43661 Binding of Chrna7 and Rac1 1 0.01 0 0.72
9 INT330104 Binding of Sh3rf1 and Rac1 1 0.13 2.41 0.62
10 INT330101 Binding of Map3k11 and Rac1 1 0.16 2.43 0.62
11 INT281132 Binding of Ccr3 and Cxcl10 1 0.00 0.25 0.6
12 INT131508 Gene_expression of Rac1 Positive_regulation of Trpv1 1 0.42 0.21 0.48
13 INT131503 Gene_expression of Rac1 Positive_regulation of Ngf 1 0.38 0.21 0.48
14 INT148930 Rac1 Regulation of Chrna7 1 0.13 0.6 0.44
15 INT337326 PIK3CD Positive_regulation of Localization of ITPR3 1 0.02 0 0.43
16 INT337325 PIK3CD Positive_regulation of Phosphorylation of IL2RG 1 0.00 0 0.43
17 INT337324 PIK3CD Positive_regulation of Gene_expression of ITPR3 1 0.02 0 0.43
18 INT131506 Rac1 Regulation of Positive_regulation of Mapk14 1 0.19 0.39 0.42
19 INT131505 Rac1 Regulation of Gene_expression of Trpv1 1 0.55 0.39 0.42
20 INT275156 Agt Positive_regulation of Rac1 1 0.03 2.89 0.4
21 INT186757 Il13 Regulation of Ccl11 2 0.21 0.17 0.39
22 INT170996 CCL11 Positive_regulation of SPARCL1 1 0.00 0.49 0.36
23 INT288537 Binding of Ccr3 and Ccl11 1 0.17 2.92 0.35
24 INT330105 Rac1 Positive_regulation of Mapk8 1 0.15 1.47 0.34
25 INT330103 Rac1 Positive_regulation of Positive_regulation of Mapk8 1 0.14 1.24 0.32
26 INT330109 Binding of Racgap1 and Rac1 1 0.03 1.22 0.32
27 INT325220 Il13 Negative_regulation of Ccl11 1 0.29 0.65 0.3
28 INT177961 Binding of CCR3 and CCL11 1 0.04 0.73 0.26
29 INT177960 Binding of IL5 and CCL11 1 0.03 0.71 0.25
30 INT80292 IL4 Positive_regulation of Gene_expression of CCL11 1 0.05 0.37 0.23
31 INT80279 IFNG Positive_regulation of Gene_expression of CCL11 1 0.06 0.37 0.23
32 INT143973 Rac1 Positive_regulation of Vti1b 1 0.00 0.16 0.2
33 INT298196 EGFR Positive_regulation of PIK3CD 1 0.04 0.65 0.18
34 INT226541 BTPs Negative_regulation of CCL11 1 0.03 0.28 0.16
35 INT140648 Binding of CRP and CCL11 1 0.14 0.88 0.13
36 INT335460 FPR1 Positive_regulation of PIK3CD 1 0.17 0 0.13
37 INT228742 Rae1 Negative_regulation of Gene_expression of Ccr3 1 0.14 0.88 0.11
38 INT275157 Binding of Stat3 and Rac1 1 0.05 0.71 0.1
39 INT275158 Rac1 Positive_regulation of Stat3 1 0.07 0.72 0.1
40 INT328435 PIK3CD Positive_regulation of Gene_expression of VEGFA 1 0.23 0.64 0.09
41 INT171709 Rac1 Negative_regulation of Localization of Chrna7 1 0.04 0.75 0.08
42 INT304100 Binding of CCL11 and Il13 1 0.05 0.86 0.08
43 INT186767 Ccl11 Regulation of Ccl5 1 0.01 0 0.07
44 INT186761 Il13 Regulation of Gene_expression of Ccl11 1 0.02 0 0.07
45 INT186771 Ccl11 Regulation of Il13 1 0.02 0 0.07
46 INT186760 Il5 Regulation of Ccl11 1 0.02 0 0.07
47 INT186762 Ccl11 Regulation of Il6 1 0.01 0 0.07
48 INT186765 Il5 Regulation of Gene_expression of Ccl11 1 0.02 0 0.07
49 INT348168 Thbs1 Positive_regulation of PIK3CD 1 0.00 0.65 0.07
50 INT302164 PTEN Regulation of PIK3CD 1 0.16 1.13 0.06
51 INT228736 Hspa9 Negative_regulation of Gene_expression of Ccr3 1 0.20 0.31 0.05
52 INT302632 Rac1 Positive_regulation of Gene_expression of Rhog 1 0.37 0.21 0.05
53 INT328438 PRB4 Negative_regulation of PIK3CD 1 0.06 0.29 0.05
54 INT304103 Il13 Positive_regulation of Gene_expression of CCL11 1 0.64 0.69 0.04
55 INT304101 Il13 Positive_regulation of CCL11 1 0.43 0.69 0.04
56 INT332286 PIK3CD Positive_regulation of MTOR 1 0.14 0.73 0.03
57 INT328436 PRB4 Negative_regulation of Gene_expression of PIK3CD 1 0.07 0.24 0.03
58 INT328430 PRB4 Regulation of Positive_regulation of PIK3CD 1 0.06 0.4 0.03
59 INT332284 IRS1 Regulation of PIK3CD 1 0.15 0.72 0.03
60 INT321402 Binding of NPHS1 and PIK3CD 1 0.02 0.73 0.03
61 INT332288 Positive_regulation of IRS1 Regulation of PIK3CD 1 0.07 0.73 0.03
62 INT288829 Binding of Rhoa and Rac1 2 0.21 1.88 0
63 INT302640 Rac1 Regulation of Gene_expression of VEGFA 1 0.03 0 0
64 INT322849 Binding of PIK3CD and PDCD10 1 0.16 0 0
65 INT342556 CCL11 Positive_regulation of Positive_regulation of EOE2 1 0.02 0.68 0
66 INT328431 PIK3CD Negative_regulation of Gene_expression of VEGFA 1 0.22 0.29 0
67 INT302641 Rac1 Regulation of TIE1 1 0.25 0.47 0
68 INT322844 Binding of KDR and PIK3CD 1 0.04 0 0
69 INT320712 Binding of NRAS and PIK3CD 1 0.21 1.66 0
70 INT254847 Rac1 Positive_regulation of Fbrs 1 0.09 0.81 0
71 INT228112 Gene_expression of Chrm2 Positive_regulation of Positive_regulation of Rac1 1 0.14 0.26 0
72 INT342552 Binding of MAPK1 and CCL11 1 0.05 1.07 0
73 INT288826 Binding of Rac1 and Vav1 1 0.25 0.68 0
74 INT342554 Positive_regulation of Binding of MAPK1 and CCL11 1 0.06 1.07 0
75 INT334474 PGGT1B Regulation of Localization of Rac1 1 0.03 0.47 0
76 INT302634 Rac1 Regulation of Gene_expression of Kdr 1 0.36 0 0
77 INT328427 PIK3CD Negative_regulation of Phosphorylation of AKT1 1 0.09 0.29 0
78 INT302633 Rac1 Regulation of Cdc42ep2 1 0.01 0 0
79 INT322848 VEGFA Positive_regulation of PIK3CD 1 0.09 0 0
80 INT322843 Positive_regulation of PIK3CD Positive_regulation of Positive_regulation of RHOA 1 0.03 0 0
81 INT320715 NRAS Positive_regulation of PIK3CD 1 0.27 1.66 0
82 INT334468 Rhoa Regulation of Localization of Rac1 1 0.25 0.18 0
83 INT254853 Rhoa Positive_regulation of Rac1 1 0.10 0.81 0
84 INT257340 Binding of Cyba and Rac1 1 0.09 0.29 0
85 INT254850 Setd1a Negative_regulation of Rac1 1 0.00 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for mast cell chemotaxis. They are ordered first by their pain relevance and then by number of times they were reported in mast cell chemotaxis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT19396 Regulation of Rac1 66 0.53 37.41 30.01
2 INT47459 Gene_expression of Rac1 101 0.68 45.27 24.33
3 INT23212 Positive_regulation of Rac1 46 0.55 32.85 15.1
4 INT27627 Binding of Rac1 41 0.41 22.88 13.68
5 INT89294 Gene_expression of Ccr3 53 0.68 43.9 12.62
6 INT102525 Gene_expression of CCR3 24 0.71 16.19 10
7 INT50055 Negative_regulation of Rac1 36 0.50 19.74 8.98
8 INT71308 Gene_expression of CCL11 33 0.76 25.66 7.83
9 INT120401 Positive_regulation of PIK3CD 33 0.45 14.89 7.37
10 INT113101 Gene_expression of Ccl11 41 0.76 22.36 5.47
11 INT105403 Positive_regulation of Gene_expression of CCR3 10 0.60 7.99 4.74
12 INT110343 Negative_regulation of PIK3CD 22 0.40 5.84 4.2
13 INT106422 Negative_regulation of Gene_expression of Rac1 4 0.43 3.97 3.41
14 INT58475 Localization of Rac1 12 0.75 5.94 3.2
15 INT78702 Positive_regulation of CCL11 13 0.68 12.94 2.74
16 INT152434 Localization of CCL11 6 0.78 9.47 2.68
17 INT186731 Positive_regulation of Ccl11 10 0.45 10.09 2.44
18 INT65928 Positive_regulation of Gene_expression of Rac1 12 0.42 3.34 2.33
19 INT181361 Localization of Ccl11 5 0.54 3.67 2.16
20 INT264967 Positive_regulation of Positive_regulation of PIK3CD 4 0.18 1.97 2.13
21 INT140650 Positive_regulation of Gene_expression of CCL11 10 0.68 5.43 2.08
22 INT117980 Regulation of Rac1 10 0.45 3.72 1.88
23 INT243799 Gene_expression of PIK3CD 15 0.45 6.63 1.5
24 INT186738 Positive_regulation of Gene_expression of Ccl11 14 0.67 8.55 1.45
25 INT78704 Binding of CCL11 10 0.37 11.38 1.44
26 INT143258 Positive_regulation of Gene_expression of Ccr3 4 0.49 3.16 1.27
27 INT16013 Gene_expression of Rac1 52 0.75 23.79 1.21
28 INT98062 Regulation of Gene_expression of Rac1 4 0.39 1.41 1.21
29 INT264969 Localization of PIK3CD 5 0.50 0.64 1.13
30 INT98061 Negative_regulation of Binding of Rac1 3 0.43 2.28 1.13
31 INT226444 Negative_regulation of CCL11 3 0.41 2.32 1.12
32 INT226434 Positive_regulation of CCR3 8 0.35 4.87 1.07
33 INT152435 Positive_regulation of Localization of CCL11 2 0.67 4.85 1.07
34 INT67174 Negative_regulation of Rac1 22 0.56 10.72 0.99
35 INT113100 Negative_regulation of Ccl11 4 0.58 4.38 0.95
36 INT81211 Transcription of Rac1 4 0.54 1.05 0.89
37 INT330097 Positive_regulation of Positive_regulation of Rac1 1 0.37 2.47 0.86
38 INT281142 Positive_regulation of Ccr3 2 0.46 0.74 0.85
39 INT264629 Localization of Rac1 8 0.72 5.7 0.79
40 INT113102 Transcription of Ccl11 4 0.52 2.48 0.77
41 INT186739 Regulation of Ccl11 4 0.39 1.99 0.75
42 INT71307 Regulation of CCL11 2 0.60 1.54 0.72
43 INT189477 Positive_regulation of Ccr3 1 0.49 4.8 0.72
44 INT115596 Regulation of Regulation of Rac1 1 0.36 0.29 0.7
45 INT186742 Negative_regulation of Gene_expression of Ccl11 3 0.50 1.65 0.69
46 INT244226 Binding of Ccl11 4 0.25 1.81 0.65
47 INT186735 Regulation of Gene_expression of Ccl11 4 0.40 2.07 0.64
48 INT264964 Positive_regulation of Localization of PIK3CD 1 0.13 0.05 0.62
49 INT171018 Negative_regulation of Gene_expression of CCL11 2 0.18 0.78 0.58
50 INT228103 Positive_regulation of Rac1 25 0.67 18.92 0.57
51 INT189475 Regulation of Gene_expression of Ccr3 4 0.32 3.17 0.54
52 INT16012 Binding of Rac1 17 0.37 6.9 0.53
53 INT170980 Transcription of CCL11 2 0.19 0.86 0.49
54 INT81212 Negative_regulation of Transcription of Rac1 1 0.01 0 0.46
55 INT154565 Regulation of Positive_regulation of PIK3CD 2 0.09 1.59 0.45
56 INT171745 Transcription of CCR3 2 0.37 2.32 0.44
57 INT87847 Regulation of Positive_regulation of Rac1 2 0.36 1.49 0.43
58 INT337345 Regulation of Gene_expression of PIK3CD 1 0.20 0 0.43
59 INT89295 Negative_regulation of Ccr3 1 0.19 1.54 0.43
60 INT337344 Negative_regulation of Negative_regulation of PIK3CD 1 0.19 0 0.4
61 INT181380 Binding of Ccr3 2 0.24 1.12 0.37
62 INT71302 Regulation of Gene_expression of CCL11 2 0.44 3.59 0.37
63 INT171036 Negative_regulation of Localization of CCL11 1 0.15 0.45 0.37
64 INT124986 Positive_regulation of Localization of Rac1 3 0.50 1.22 0.33
65 INT308532 Positive_regulation of Positive_regulation of CCR3 1 0.01 2.33 0.32
66 INT102526 Negative_regulation of Gene_expression of CCR3 1 0.21 0.33 0.31
67 INT112551 Protein_catabolism of Rac1 2 0.66 0.29 0.3
68 INT116729 Regulation of Localization of Rac1 1 0.01 0.07 0.29
69 INT99682 Phosphorylation of Rac1 1 0.54 0.72 0.28
70 INT140649 Positive_regulation of Binding of CCL11 1 0.49 1.38 0.27
71 INT162873 Negative_regulation of Negative_regulation of Rac1 1 0.34 0.35 0.26
72 INT330090 Regulation of Negative_regulation of Rac1 1 0.36 0.53 0.25
73 INT177967 Binding of CCR3 1 0.16 0.72 0.25
74 INT330093 Negative_regulation of Positive_regulation of Rac1 1 0.34 0.88 0.23
75 INT189484 Regulation of Ccr3 1 0.19 1.07 0.23
76 INT288535 Positive_regulation of Localization of Ccl11 1 0.32 1.19 0.21
77 INT308528 Regulation of CCR3 2 0.31 2.23 0.2
78 INT186733 Regulation of Positive_regulation of Ccl11 1 0.06 0.58 0.2
79 INT168055 Regulation of Transcription of Rac1 1 0.36 0.34 0.16
80 INT302261 Regulation of PIK3CD 7 0.29 5.34 0.15
81 INT133599 Positive_regulation of Binding of Rac1 2 0.40 0.4 0.15
82 INT330085 Regulation of Binding of Rac1 1 0.36 0.28 0.15
83 INT243793 Phosphorylation of PIK3CD 5 0.42 1.74 0.13
84 INT226468 Localization of CCR3 1 0.30 0.28 0.11
85 INT334510 Negative_regulation of CCR3 1 0.30 1.4 0.1
86 INT226489 Protein_catabolism of CCL11 1 0.21 0.27 0.1
87 INT302613 Positive_regulation of Gene_expression of Rac1 14 0.67 3.7 0.08
88 INT328448 Negative_regulation of Gene_expression of PIK3CD 1 0.21 0.84 0.08
89 INT334443 Positive_regulation of Positive_regulation of Rac1 1 0.33 1.1 0.08
90 INT302624 Negative_regulation of Gene_expression of Rac1 1 0.56 3.67 0.06
91 INT334509 Negative_regulation of Negative_regulation of CCR3 1 0.30 0.7 0.05
92 INT323949 Negative_regulation of Positive_regulation of Rac1 1 0.23 0.53 0.05
93 INT334445 Regulation of Positive_regulation of Rac1 1 0.40 1.73 0.04
94 INT302611 Regulation of Gene_expression of Rac1 1 0.43 4.5 0.03
95 INT302615 Transcription of Rac1 5 0.66 1.1 0
96 INT320732 Binding of PIK3CD 3 0.20 1.66 0
97 INT334450 Regulation of Localization of Rac1 1 0.30 0.65 0
98 INT228095 Phosphorylation of Rac1 1 0.34 0.21 0
99 INT302609 Positive_regulation of Transcription of Rac1 1 0.48 0.27 0
100 INT302631 Regulation of Transcription of Rac1 1 0.43 0.47 0
101 INT302621 Regulation of Negative_regulation of Rac1 1 0.43 0 0
102 INT302627 Negative_regulation of Localization of Rac1 1 0.41 0.28 0
103 INT228717 Negative_regulation of Gene_expression of Ccr3 1 0.36 0.16 0
104 INT302620 Negative_regulation of Transcription of Rac1 1 0.41 0 0
105 INT311855 Regulation of Negative_regulation of PIK3CD 1 0.04 0.28 0
106 INT334438 Positive_regulation of Localization of Rac1 1 0.33 2.37 0
107 INT254786 Positive_regulation of Negative_regulation of Rac1 1 0.26 0.95 0
108 INT302614 Positive_regulation of Binding of Rac1 1 0.48 0.31 0
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