GO:0002553

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Name histamine secretion by mast cell
Categary Process
Go Slim No
Go Link GO:0002553
Unique Molecular Interactions 23
Total Molecular Interactions 25
Total Single Events 212
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for histamine secretion by mast cell. They are ordered first by their pain relevance and then by number of times they were reported for histamine secretion by mast cell. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT149386 Binding of Lyn and TRPV4 1 0.40 1.14 0.91
2 INT339532 FGF2 Positive_regulation of YWHAZ 1 0.00 1.26 0.54
3 INT193784 ITIH4 Positive_regulation of YWHAZ 1 0.04 1.21 0.34
4 INT215653 Binding of Adora1 and Adora3 1 0.39 0.07 0.27
5 INT224127 Grk5 Positive_regulation of Phosphorylation of Adora3 1 0.06 0 0.13
6 INT224125 Adrbk2 Positive_regulation of Phosphorylation of Adora3 1 0.04 0 0.13
7 INT129091 Binding of PIK3CG and Lyn 1 0.00 0.47 0.12
8 INT129075 Binding of Pik3r1 and Lyn 1 0.00 0.47 0.12
9 INT129093 Binding of Lyn and TCHP 1 0.00 0.49 0.12
10 INT129092 Binding of GRP and Lyn 1 0.00 0.48 0.12
11 INT310695 Binding of Btk and Pla2g6 1 0.18 0.16 0.12
12 INT200814 Epo Positive_regulation of Lyn 1 0.36 1.42 0.03
13 INT278388 Msu Positive_regulation of Phosphorylation of Lyn 1 0.17 0.12 0
14 INT261838 Lyn Regulation of Trpv4 1 0.03 0.19 0
15 INT261843 Lyn Regulation of Regulation of Trpv4 1 0.03 0.19 0
16 INT347226 Hck Regulation of Gene_expression of Lyn 1 0.10 0.08 0
17 INT241539 Binding of Abl1 and Lyn 1 0.09 0.14 0
18 INT200818 Akt1 Positive_regulation of Negative_regulation of Lyn 1 0.25 1.02 0
19 INT241538 Negative_regulation of Binding of Abl1 and Lyn 1 0.11 0.14 0
20 INT347224 Lyn Regulation of Positive_regulation of Bcr 1 0.14 0.07 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for histamine secretion by mast cell. They are ordered first by their pain relevance and then by number of times they were reported in histamine secretion by mast cell. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT111384 Gene_expression of Adora3 18 0.75 10.53 5.73
2 INT124136 Positive_regulation of YWHAZ 7 0.67 1.85 4.51
3 INT146946 Gene_expression of Lyn 16 0.76 8.9 3.75
4 INT111385 Negative_regulation of Adora3 7 0.43 3.91 2.8
5 INT146945 Positive_regulation of Lyn 6 0.49 2.81 2.25
6 INT124138 Gene_expression of YWHAZ 9 0.62 4.04 2.21
7 INT52523 Positive_regulation of Adora3 2 0.49 1.39 1.79
8 INT124137 Positive_regulation of Positive_regulation of YWHAZ 1 0.67 0 1.7
9 INT17885 Negative_regulation of YWHAZ 6 0.56 2.74 1.58
10 INT194849 Negative_regulation of Gene_expression of Adora3 2 0.18 2.08 1.29
11 INT124135 Positive_regulation of Gene_expression of YWHAZ 2 0.45 0.21 1.05
12 INT274898 Positive_regulation of Positive_regulation of Lyn 1 0.35 1.51 1.05
13 INT52524 Regulation of Adora3 3 0.44 1.17 0.96
14 INT146939 Negative_regulation of Lyn 3 0.53 2.97 0.95
15 INT149383 Binding of Lyn 1 0.36 1.14 0.91
16 INT215602 Localization of Adora3 2 0.73 0.63 0.7
17 INT117091 Positive_regulation of Lyn 1 0.49 0.41 0.56
18 INT282809 Negative_regulation of Positive_regulation of YWHAZ 1 0.03 1.07 0.52
19 INT224043 Phosphorylation of Adora3 1 0.15 0.2 0.43
20 INT215609 Transcription of Adora3 2 0.62 0.35 0.31
21 INT281933 Localization of YWHAZ 2 0.09 1.08 0.27
22 INT261820 Phosphorylation of Lyn 5 0.30 1.41 0.2
23 INT304142 Negative_regulation of Phosphorylation of Lyn 1 0.12 1.11 0.2
24 INT131541 Negative_regulation of Gene_expression of YWHAZ 1 0.27 0.39 0.17
25 INT131539 Regulation of Gene_expression of YWHAZ 1 0.17 0.39 0.17
26 INT257835 Negative_regulation of Btk 6 0.41 2.41 0.16
27 INT278361 Positive_regulation of Gene_expression of Lyn 6 0.41 0.63 0.15
28 INT304452 Regulation of Lyn 1 0.17 0 0.15
29 INT224050 Negative_regulation of Phosphorylation of Adora3 1 0.10 0.08 0.11
30 INT224044 Regulation of Regulation of Adora3 1 0.06 0.09 0.11
31 INT241734 Regulation of Transcription of Adora3 1 0.39 0.27 0.07
32 INT241509 Negative_regulation of Gene_expression of Lyn 2 0.20 1.02 0.05
33 INT315847 Positive_regulation of Negative_regulation of Lyn 1 0.18 0.61 0.05
34 INT215605 Positive_regulation of Localization of Adora3 1 0.49 0 0.05
35 INT355368 Regulation of Btk 1 0.01 0.39 0.04
36 INT315844 Binding of Btk 2 0.16 0.59 0.03
37 INT304408 Regulation of YWHAZ 1 0.21 0.14 0.03
38 INT257834 Gene_expression of Btk 7 0.65 3.45 0
39 INT278323 Positive_regulation of Phosphorylation of Lyn 1 0.22 0 0
40 INT278322 Negative_regulation of Localization of Lyn 1 0.20 0.11 0
41 INT286540 Localization of Btk 1 0.28 1.26 0
42 INT278356 Localization of Lyn 1 0.35 0.11 0
43 INT315841 Protein_catabolism of Btk 1 0.12 0.29 0
44 INT155732 Transcription of YWHAZ 1 0.16 0 0
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