GO:0002573

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Name myeloid leukocyte differentiation
Categary Process
Go Slim No
Go Link GO:0002573
Unique Molecular Interactions 80
Total Molecular Interactions 109
Total Single Events 1388
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for myeloid leukocyte differentiation. They are ordered first by their pain relevance and then by number of times they were reported for myeloid leukocyte differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT111076 Psen1 Regulation of Psenen 1 0.17 0.76 1.58
2 INT117008 Sfpi1 Regulation of Oprm1 1 0.56 0.56 1.49
3 INT99577 Binding of KITLG and Kit 3 0.34 2.33 1.11
4 INT117005 Sfpi1 Positive_regulation of Oprm1 1 0.52 0.56 0.94
5 INT99578 Binding of CEL and Kit 1 0.04 1.07 0.81
6 INT151453 Gtf3a Regulation of Kit 1 0.04 0.25 0.78
7 INT117007 Binding of Oprm1 and Sfpi1 1 0.50 0.07 0.63
8 INT117006 Sfpi1 Negative_regulation of Oprm1 1 0.39 0.29 0.49
9 INT261652 Binding of MAPK1 and PSEN1 1 0.22 1.25 0.41
10 INT327727 Atp6v0a2 Negative_regulation of Gene_expression of Kit 1 0.05 0.83 0.41
11 INT148246 Binding of KITLG and Positive_regulation of Kit 1 0.04 0.43 0.38
12 INT148247 KITLG Positive_regulation of Kit 1 0.03 0.43 0.38
13 INT148243 Binding of Akt1 and Kit 1 0.03 0.44 0.35
14 INT148240 Binding of Kit and Ret 1 0.24 0.44 0.35
15 INT148241 Binding of Kit and Ntrk1 1 0.25 0.44 0.35
16 INT148242 Binding of Kit and Gtf3a 1 0.04 0.34 0.3
17 INT258343 Binding of Aicda and Kit 1 0.06 0.57 0.26
18 INT297547 Pou3f3 Regulation of Psen1 1 0.00 0.41 0.25
19 INT213800 Kit Positive_regulation of Mitf 1 0.30 1.24 0.15
20 INT302826 Negative_regulation of Binding of Il2 and Kit 1 0.01 1.28 0.14
21 INT302827 Binding of Il2 and Kit 1 0.01 1.27 0.14
22 INT213797 Kit Positive_regulation of Tfe3 1 0.28 1.24 0.14
23 INT94763 PSEN2 Regulation of Positive_regulation of App 1 0.11 0.72 0.14
24 INT297543 Neurod1 Regulation of Psen1 1 0.00 0.2 0.12
25 INT234222 PSEN1 Regulation of Gene_expression of NOTCH1 1 0.03 0 0.08
26 INT193959 Psen1 Regulation of App 1 0.40 0.58 0.08
27 INT193954 Binding of App and Psen1 3 0.38 0.88 0.06
28 INT273288 Psen1 Regulation of Prdx2 1 0.01 0.7 0.06
29 INT293494 Sfpi1 Regulation of Negative_regulation of Hsp90aa1 1 0.04 0.23 0.05
30 INT193967 Binding of PSEN1 and Psen1 1 0.41 1.2 0.05
31 INT193970 Binding of PSEN1 and Psen2 1 0.36 2.06 0.05
32 INT356101 App Regulation of Negative_regulation of Psen1 1 0.23 0.31 0.04
33 INT331477 PSEN2 Regulation of Gene_expression of Psen1 1 0.00 0.15 0.03
34 INT354896 Binding of Psen2 and Fancd2 1 0.04 0.75 0.03
35 INT254282 Sfpi1 Positive_regulation of Binding of Pam16 1 0.02 0.23 0.03
36 INT331478 Psen1 Regulation of Gene_expression of PSEN2 1 0.00 0.15 0.03
37 INT254285 Sfpi1 Positive_regulation of Gene_expression of THPO 1 0.02 0.17 0.03
38 INT193946 Binding of Notch1 and Positive_regulation of Psen1 1 0.03 0.06 0
39 INT201620 Binding of Kit and Uvbi1 1 0.03 0.2 0
40 INT284296 Mir155 Regulation of Spi1 1 0.25 0.36 0
41 INT193962 Binding of Psen1 and Ncstn 1 0.13 0.08 0
42 INT334644 Binding of PSEN1 and TTN 1 0.01 0 0
43 INT350098 Gene_expression of PSEN2 Positive_regulation of Gene_expression of Hmox1 1 0.39 0 0
44 INT241500 Binding of Kit and Kitl 1 0.08 0.92 0
45 INT273289 Binding of Psen2 and Ryr2 1 0.27 4.53 0
46 INT293492 Hsp90aa1 Regulation of Gene_expression of Sfpi1 1 0.04 0.1 0
47 INT350715 Sfpi1 Positive_regulation of Transcription of MIR424 1 0.09 0.25 0
48 INT211572 Binding of Kit and Pik3r1 1 0.21 0.06 0
49 INT217398 Binding of Psen2 and Bace1 1 0.12 1.44 0
50 INT193955 Binding of Psen1 and Psen2 1 0.37 1.64 0
51 INT193948 Binding of Psen1 and Notch1 1 0.02 0 0
52 INT286331 Binding of Psen1 and Ror1 1 0.27 0 0
53 INT211570 Kit Regulation of Gene_expression of Lpin1 1 0.27 0.12 0
54 INT282743 Hsp90aa1 Positive_regulation of Kit 1 0.22 0.54 0
55 INT347035 Binding of Kit and Cd34 1 0.02 1.38 0
56 INT193968 Binding of PSEN1 and Ps 1 0.07 0.66 0
57 INT211574 Regulation of Binding of Kit and Pik3r1 1 0.16 0.06 0
58 INT262712 Psen1 Regulation of Gene_expression of Bace1 1 0.22 0.07 0
59 INT217400 Binding of Psen1 and Bace1 1 0.17 1.43 0
60 INT286337 PSENEN Regulation of Psen1 1 0.07 0.37 0
61 INT193958 Binding of Pld1 and Psen1 1 0.17 0 0
62 INT304168 Binding of Gata1 and Sfpi1 1 0.08 0.07 0
63 INT201612 Binding of Kit and Mc1r 1 0.34 0.13 0
64 INT193953 Binding of Bcl2l1 and Psen1 1 0.07 0.66 0
65 INT193956 Binding of Psen1 and Rab6a 1 0.15 0 0
66 INT294428 PSEN2 Regulation of Gene_expression of Tp53 1 0.49 0.86 0
67 INT294429 PSEN2 Negative_regulation of Tp53 1 0.46 1.03 0
68 INT193957 Binding of Bcl2l1 and Psen2 1 0.07 0.66 0
69 INT331479 Binding of PSEN2 and Psen1 1 0.00 0.07 0
70 INT312379 KIT Positive_regulation of Positive_regulation of Kit 1 0.01 1.37 0
71 INT234221 Negative_regulation of PSEN1 Negative_regulation of Gene_expression of APP 1 0.33 0.32 0
72 INT211571 Pik3r1 Positive_regulation of Gene_expression of Kit 1 0.30 0.3 0
73 INT350705 Sfpi1 Positive_regulation of Mir223 1 0.04 0.13 0
74 INT334645 Binding of PSEN1 and HM13 1 0.01 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for myeloid leukocyte differentiation. They are ordered first by their pain relevance and then by number of times they were reported in myeloid leukocyte differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT91891 Gene_expression of Kit 268 0.78 158.89 22.67
2 INT111073 Gene_expression of Psen1 167 0.76 78.65 15.83
3 INT91772 Gene_expression of PSEN1 115 0.75 38.12 8.48
4 INT111069 Regulation of Psen1 19 0.44 7.78 5.87
5 INT60724 Gene_expression of Psen2 30 0.72 27 5.79
6 INT117004 Gene_expression of Sfpi1 21 0.75 15.95 5.29
7 INT111067 Positive_regulation of Gene_expression of Psen1 32 0.68 21.2 4.19
8 INT88278 Binding of Kit 33 0.37 24.45 4.13
9 INT124185 Negative_regulation of Kit 57 0.59 35.43 3.61
10 INT211591 Negative_regulation of PSEN1 14 0.57 5.73 3.26
11 INT91890 Positive_regulation of Kit 36 0.50 25.44 3.06
12 INT91761 Gene_expression of PSEN2 38 0.75 22.93 3.03
13 INT193936 Positive_regulation of PSEN1 5 0.58 11.57 2.95
14 INT163544 Binding of Psen1 40 0.36 15.28 2.42
15 INT151449 Negative_regulation of Gene_expression of Kit 18 0.45 12.05 2.23
16 INT181507 Positive_regulation of Psen1 22 0.49 7.59 2.04
17 INT60723 Localization of Psen2 5 0.68 2.11 2.02
18 INT99572 Localization of Kit 13 0.75 5.23 1.95
19 INT193939 Binding of PSEN1 10 0.36 6.16 1.93
20 INT140175 Regulation of Kit 23 0.62 8.59 1.79
21 INT111070 Negative_regulation of Gene_expression of Psen1 17 0.42 9.47 1.77
22 INT117003 Binding of Sfpi1 5 0.47 5.04 1.74
23 INT282434 Regulation of Gene_expression of Psen1 9 0.50 2.85 1.52
24 INT151450 Positive_regulation of Gene_expression of Kit 23 0.69 13.11 1.43
25 INT78646 Regulation of Psen2 4 0.20 1.78 1.42
26 INT181509 Negative_regulation of Psen1 17 0.57 11.53 1.35
27 INT78645 Negative_regulation of Gene_expression of Psen2 1 0.14 0.13 1.01
28 INT117002 Negative_regulation of Sfpi1 16 0.58 9.72 1
29 INT232636 Positive_regulation of Binding of Kit 4 0.39 1.98 0.98
30 INT91771 Positive_regulation of Gene_expression of PSEN1 13 0.49 8.93 0.93
31 INT78647 Positive_regulation of Localization of Psen2 1 0.16 0.14 0.83
32 INT237406 Positive_regulation of Binding of Psen1 1 0.29 0 0.8
33 INT94756 Positive_regulation of PSEN2 8 0.49 4.59 0.77
34 INT286313 Transcription of Psen1 9 0.70 2.26 0.76
35 INT193849 Positive_regulation of Gene_expression of Psen2 5 0.44 4.92 0.76
36 INT78649 Binding of Psen2 7 0.36 5.9 0.73
37 INT78648 Regulation of Binding of Psen2 1 0.14 0.2 0.73
38 INT91765 Positive_regulation of Gene_expression of PSEN2 8 0.49 4.57 0.63
39 INT189438 Regulation of Gene_expression of Kit 10 0.45 4.94 0.61
40 INT217394 Regulation of Binding of PSEN1 1 0.44 1.58 0.53
41 INT316041 Transcription of Psen2 1 0.64 1.1 0.45
42 INT213789 Phosphorylation of Kit 7 0.69 5.32 0.43
43 INT234249 Regulation of PSEN1 6 0.37 2.21 0.43
44 INT234257 Regulation of Gene_expression of PSEN1 6 0.44 1.98 0.42
45 INT193856 Localization of Psen1 19 0.73 9.79 0.41
46 INT151963 Negative_regulation of Positive_regulation of Kit 1 0.37 0.31 0.4
47 INT36396 Positive_regulation of Psen2 6 0.44 4.57 0.39
48 INT181025 Localization of Sfpi1 3 0.80 4.96 0.38
49 INT177773 Localization of PSEN1 4 0.73 0.89 0.36
50 INT84555 Negative_regulation of Spi1 6 0.42 0.71 0.34
51 INT261682 Positive_regulation of Positive_regulation of PSEN2 1 0.21 0.55 0.33
52 INT155426 Gene_expression of Kit 3 0.49 2.71 0.31
53 INT181020 Positive_regulation of Gene_expression of Sfpi1 2 0.67 1.11 0.31
54 INT181051 Transcription of Sfpi1 1 0.62 1.1 0.29
55 INT224298 Negative_regulation of PSEN2 6 0.57 2.29 0.28
56 INT316045 Negative_regulation of Negative_regulation of Psen1 1 0.42 1.58 0.27
57 INT213777 Positive_regulation of Phosphorylation of Kit 2 0.58 1.36 0.26
58 INT261676 Negative_regulation of Positive_regulation of PSEN1 1 0.36 1.59 0.25
59 INT172525 Localization of PSEN2 5 0.73 4.17 0.24
60 INT101308 Positive_regulation of Spi1 2 0.67 0.38 0.23
61 INT181036 Positive_regulation of Sfpi1 3 0.49 0.96 0.21
62 INT181508 Regulation of Regulation of Psen1 2 0.33 0.51 0.2
63 INT101309 Gene_expression of Spi1 2 0.75 0.64 0.18
64 INT101307 Positive_regulation of Gene_expression of Spi1 1 0.67 0.28 0.18
65 INT106451 Regulation of Spi1 1 0.43 0 0.18
66 INT286317 Positive_regulation of Transcription of Psen1 1 0.37 0.32 0.17
67 INT181033 Regulation of Sfpi1 2 0.40 1.58 0.13
68 INT336359 Positive_regulation of Phosphorylation of Psen1 1 0.33 0.4 0.13
69 INT336361 Phosphorylation of Psen1 1 0.54 0.34 0.13
70 INT176595 Negative_regulation of Gene_expression of PSEN2 1 0.24 1.01 0.11
71 INT193841 Regulation of Gene_expression of Psen2 1 0.40 1.66 0.11
72 INT201694 Negative_regulation of Gene_expression of PSEN1 3 0.41 2.31 0.1
73 INT326104 Binding of Kit 1 0.30 0.39 0.1
74 INT199124 Transcription of Kit 6 0.67 1.49 0.09
75 INT229573 Positive_regulation of Positive_regulation of Kit 3 0.39 1.46 0.09
76 INT273285 Negative_regulation of Localization of Psen1 1 0.36 0.99 0.09
77 INT109131 Regulation of PSEN2 3 0.44 0.55 0.08
78 INT193862 Positive_regulation of Positive_regulation of Psen1 3 0.49 0.9 0.08
79 INT193872 Positive_regulation of Localization of Psen1 3 0.49 1.39 0.08
80 INT261678 Positive_regulation of Positive_regulation of PSEN1 1 0.42 0.62 0.08
81 INT193890 Regulation of Positive_regulation of Psen1 1 0.44 0.66 0.08
82 INT193938 Phosphorylation of PSEN1 5 0.79 1.6 0.07
83 INT163458 Negative_regulation of Regulation of Kit 2 0.12 1.61 0.06
84 INT200837 Negative_regulation of Binding of Kit 2 0.23 0.94 0.06
85 INT176592 Transcription of PSEN2 5 0.33 0.41 0.05
86 INT193859 Negative_regulation of Binding of Psen1 3 0.42 1.85 0.05
87 INT331406 Negative_regulation of Regulation of Psen1 1 0.04 0.09 0.05
88 INT193865 Protein_catabolism of Psen1 10 0.97 0.37 0.04
89 INT241510 Negative_regulation of Phosphorylation of Kit 3 0.31 2.06 0.03
90 INT310472 Negative_regulation of Gene_expression of Sfpi1 1 0.41 0.23 0.03
91 INT224302 Negative_regulation of Transcription of PSEN2 3 0.26 0.08 0
92 INT265229 Binding of PSEN2 2 0.16 1.37 0
93 INT211563 Regulation of Negative_regulation of Kit 1 0.45 0.19 0
94 INT282736 Protein_catabolism of Kit 1 0.55 0.54 0
95 INT286327 Regulation of Binding of Psen1 1 0.33 0.16 0
96 INT284294 Transcription of Spi1 1 0.67 0.36 0
97 INT234250 Positive_regulation of Negative_regulation of PSEN1 1 0.41 0 0
98 INT284295 Negative_regulation of Gene_expression of Spi1 1 0.41 0.36 0
99 INT193886 Regulation of Protein_catabolism of Psen1 1 0.44 0.06 0
100 INT193934 Positive_regulation of Binding of PSEN1 1 0.49 0.92 0
101 INT232629 Positive_regulation of Localization of Kit 1 0.44 0.8 0
102 INT224297 Regulation of Transcription of PSEN2 1 0.20 0.06 0
103 INT331407 Negative_regulation of Transcription of Psen1 1 0.04 0.08 0
104 INT177774 Transcription of PSEN1 1 0.33 0.09 0
105 INT106452 Negative_regulation of Positive_regulation of Spi1 1 0.30 0 0
106 INT232632 Regulation of Localization of Kit 1 0.40 0.81 0
107 INT211533 Regulation of Regulation of Kit 1 0.62 0.24 0
108 INT282731 Positive_regulation of Protein_catabolism of Kit 1 0.39 0.54 0
109 INT250466 Regulation of Gene_expression of Sfpi1 1 0.39 0.98 0
110 INT312378 Positive_regulation of Kit 1 0.04 1.36 0
111 INT354892 Negative_regulation of Psen2 1 0.37 0.95 0
112 INT293482 Protein_catabolism of Sfpi1 1 0.09 0.52 0
113 INT193844 Positive_regulation of Protein_catabolism of Psen1 1 0.49 0.05 0
114 INT331463 Regulation of Gene_expression of PSEN2 1 0.04 0 0
115 INT234258 Negative_regulation of Phosphorylation of PSEN1 1 0.35 0.49 0
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