GO:0002576

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Name platelet degranulation
Categary Process
Go Slim No
Go Link GO:0002576
Unique Molecular Interactions 1812
Total Molecular Interactions 2617
Total Single Events 20685
Pain Genes Associated 66

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for platelet degranulation. They are ordered first by their pain relevance and then by number of times they were reported for platelet degranulation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT107331 Binding of PPBP and Adarb1 1 0.01 0 3.67
2 INT147107 TGFB1 Positive_regulation of Gene_expression of NGF 1 0.49 0.67 2.69
3 INT146930 CAP1 Regulation of ABCB1 1 0.29 0.3 2.19
4 INT66157 Binding of ALB and BDP1 1 0.11 0 2.13
5 INT113550 Binding of FN1 and VTN 6 0.30 5.24 1.91
6 INT166947 Ngf Positive_regulation of KNG1 1 0.00 0.47 1.86
7 INT224432 TNF Positive_regulation of Gene_expression of VEGFA 1 0.13 5.83 1.8
8 INT302646 ARSA Positive_regulation of TGFB1 1 0.10 0.52 1.76
9 INT129717 TGFB1 Positive_regulation of Gene_expression of TNFRSF10D 3 0.38 4.29 1.71
10 INT94617 KNG1 Positive_regulation of Localization of Calca 1 0.00 0.75 1.7
11 INT94618 KNG1 Positive_regulation of Calca 1 0.00 0.75 1.66
12 INT322412 PPBP Negative_regulation of Phosphorylation of Akt1 1 0.01 0 1.65
13 INT103592 CAP1 Negative_regulation of Gene_expression of CPOX 1 0.19 1.52 1.64
14 INT187175 Binding of BSG and PPIA 1 0.14 2.23 1.64
15 INT147108 TGFB1 Positive_regulation of Gene_expression of FN1 4 0.47 1.01 1.63
16 INT209853 TNF Regulation of Gene_expression of CD36 1 0.61 3.41 1.59
17 INT326509 Binding of ACE and VWF 1 0.05 2.07 1.59
18 INT266406 Binding of APP and Ager 1 0.00 2.34 1.57
19 INT66713 Binding of BDKRB1 and KNG1 2 0.22 0.39 1.53
20 INT61443 Binding of KNG1 and Tyr 1 0.00 0 1.46
21 INT151514 Olfr155 Negative_regulation of Gene_expression of VEGFA 1 0.00 1.8 1.42
22 INT225019 PDGFB Positive_regulation of Gene_expression of Cxcl1 1 0.27 0.54 1.4
23 INT56093 FGFR1 Regulation of Gene_expression of SERPINE1 1 0.23 1.71 1.37
24 INT126639 KNG1 Positive_regulation of Alox15 1 0.17 0.62 1.36
25 INT126640 Negative_regulation of KNG1 Positive_regulation of Alox15 1 0.14 0.62 1.36
26 INT351205 VEGFA Positive_regulation of Binding of MRGPRX1 1 0.08 0.65 1.35
27 INT178986 Binding of MMP9 and TIMP1 4 0.47 2.58 1.33
28 INT56087 TNF Regulation of Gene_expression of SERPINE1 1 0.43 1.67 1.33
29 INT121457 KNG1 Positive_regulation of Trpv1 1 0.16 0.91 1.33
30 INT39950 Binding of ALB and PDYN 1 0.31 0 1.32
31 INT131185 PTH Positive_regulation of Gene_expression of IGF1 3 0.44 3.31 1.31
32 INT131184 PTGER2 Positive_regulation of Gene_expression of IGF1 1 0.63 2.47 1.29
33 INT42579 SOD1 Negative_regulation of POMC 1 0.16 0.43 1.27
34 INT254355 PF4 Positive_regulation of IFNA1 1 0.04 1.23 1.26
35 INT197092 TNF Regulation of VEGFA 4 0.21 2.78 1.22
36 INT299299 VEGFA Positive_regulation of SRC 1 0.20 0.91 1.2
37 INT75483 Binding of SGCG and TGFB1 1 0.52 2.27 1.19
38 INT142077 TGFB1 Negative_regulation of Binding of IDO1 1 0.15 2.07 1.19
39 INT220751 EGF Regulation of GOPC 1 0.08 0 1.18
40 INT220752 Negative_regulation of EGF Regulation of NAV1 1 0.26 0 1.18
41 INT220753 Negative_regulation of EGF Regulation of GOPC 1 0.08 0 1.18
42 INT182159 Binding of HGF and DCPS 1 0.01 2.5 1.17
43 INT220748 EGF Regulation of NAV1 1 0.28 0 1.17
44 INT19535 Binding of ADRA1D and ALB 3 0.42 0.8 1.15
45 INT193288 CAP1 Positive_regulation of Pth 1 0.04 0.08 1.14
46 INT99691 Pdpk1 Positive_regulation of Positive_regulation of VEGFA 1 0.01 0.72 1.11
47 INT173059 Binding of KDR and VEGFA 43 0.43 29.63 1.1
48 INT136989 EGF Negative_regulation of Positive_regulation of KCNJ2 1 0.04 1.09 1.1
49 INT74939 IL1B Positive_regulation of Gene_expression of HGF 1 0.58 0.72 1.09
50 INT202968 Binding of MCRS1 and CAP1 1 0.03 2.46 1.08
51 INT168529 APP Regulation of FSIP1 2 0.65 2.26 1.07
52 INT150794 ZNF398 Positive_regulation of Localization of THBS1 1 0.09 1.02 1.07
53 INT150789 THBS3 Negative_regulation of THBS1 1 0.18 1.01 1.06
54 INT150787 ZNF398 Positive_regulation of Gene_expression of SPARC 1 0.13 1.02 1.05
55 INT97013 Negative_regulation of Binding of CALM3 and OPRM1 1 0.40 0 1.05
56 INT97011 Binding of CALM3 and OPRM1 1 0.35 0 1.05
57 INT136988 EGF Negative_regulation of KCNJ2 1 0.04 1.09 1.04
58 INT106706 POMC Negative_regulation of Binding of FN1 1 0.19 0.79 1.02
59 INT54737 PPBP Regulation of NCOR2 1 0.01 0.15 1.01
60 INT73681 Regulation of KNG1 Positive_regulation of ALB 1 0.30 0.38 0.99
61 INT124918 Binding of PLEK and Maob 1 0.10 1.05 0.98
62 INT73680 KNG1 Positive_regulation of ALB 1 0.51 0.38 0.98
63 INT140653 IGF1 Negative_regulation of Protein_catabolism of PARP1 1 0.32 0.63 0.98
64 INT140652 IGF1 Positive_regulation of Phosphorylation of MAPK1 1 0.26 0.63 0.98
65 INT209852 TNF Negative_regulation of Gene_expression of CD36 1 0.43 0.61 0.98
66 INT93306 Binding of TRPV1 and CAP1 2 0.18 0.07 0.97
67 INT66712 Binding of BDKRB2 and KNG1 1 0.06 0.22 0.97
68 INT66711 Negative_regulation of Binding of BDKRB2 and KNG1 1 0.07 0.22 0.97
69 INT303690 KNG1 Positive_regulation of CPOX 1 0.01 0.76 0.96
70 INT93307 CAP1 Positive_regulation of TRPV1 1 0.15 0.07 0.96
71 INT66714 Negative_regulation of Binding of BDKRB1 and KNG1 1 0.13 0.22 0.96
72 INT161231 Positive_regulation of Htr1a Positive_regulation of Gene_expression of VEGFA 1 0.67 0.16 0.95
73 INT129206 RYBP Positive_regulation of Gene_expression of TGFB1 1 0.00 1.04 0.95
74 INT137922 VEGFA Positive_regulation of Oprm1 1 0.06 0 0.94
75 INT102554 HGF Positive_regulation of Phosphorylation of RPS6KA1 1 0.21 0.93 0.94
76 INT137923 VEGFA Positive_regulation of Phosphorylation of Akt1 1 0.05 0 0.93
77 INT222979 Negative_regulation of Binding of COL1A1 and FN1 1 0.01 1.64 0.93
78 INT137921 VEGFA Positive_regulation of Ephb2 1 0.03 0 0.93
79 INT222978 Binding of COL1A1 and FN1 1 0.01 1.64 0.92
80 INT193291 Binding of CAP1 and Cfd 1 0.02 0.13 0.91
81 INT149386 Binding of Lyn and TRPV4 1 0.40 1.14 0.91
82 INT118288 EGF Positive_regulation of Phosphorylation of EGFR 9 0.54 3.85 0.9
83 INT138862 ABCC2 Negative_regulation of ABCC4 1 0.63 0.24 0.9
84 INT113946 Binding of FLNA and OPRM1 1 0.10 0.37 0.9
85 INT220744 EGF Positive_regulation of Gene_expression of KRT20 1 0.01 1.26 0.9
86 INT169477 TGFB3 Positive_regulation of Spink3 1 0.02 1.83 0.89
87 INT84369 Ngf Positive_regulation of KNG1 1 0.04 0.29 0.89
88 INT134454 EGF Positive_regulation of EGFR 3 0.56 1.32 0.88
89 INT96008 Binding of KNG1 and EBP 1 0.01 0.15 0.88
90 INT96010 KNG1 Positive_regulation of Binding of MTG1 1 0.32 0.15 0.88
91 INT134453 Negative_regulation of EGF Positive_regulation of EGFR 1 0.35 0.35 0.88
92 INT96009 KNG1 Positive_regulation of MTG1 1 0.32 0.15 0.88
93 INT196523 Binding of MMP2 and TIMP1 3 0.43 1.94 0.85
94 INT222985 CP Positive_regulation of Positive_regulation of TGFB1 1 0.00 1.57 0.85
95 INT338695 CAP1 Regulation of Trpv1 1 0.01 0.14 0.85
96 INT107698 FN1 Positive_regulation of Gene_expression of CPOX 1 0.13 0.26 0.84
97 INT167431 Binding of APP and MYO1C 1 0.23 1.38 0.83
98 INT225690 KNG1 Positive_regulation of TRPV1 1 0.42 0.7 0.83
99 INT153516 PLG Positive_regulation of Pas5a 1 0.57 0.05 0.83
100 INT116108 VEGFA Positive_regulation of SEC23IP 1 0.10 0.3 0.83
101 INT116109 VEGFA Positive_regulation of PTK2 1 0.13 0.3 0.83
102 INT193322 KNG1 Positive_regulation of Prh1 1 0.00 0.51 0.83
103 INT220739 EGF Positive_regulation of Transcription of NAV1 1 0.31 0.16 0.83
104 INT116106 VEGFA Positive_regulation of AKT1 1 0.12 0.3 0.83
105 INT218037 Binding of ALB and Penk 1 0.13 0 0.81
106 INT110726 Binding of ALB and LTF 1 0.01 0 0.81
107 INT84039 EGF Positive_regulation of Gene_expression of CPOX 2 0.11 1.88 0.8
108 INT84040 EGF Positive_regulation of CPOX 2 0.07 1.91 0.8
109 INT220747 Binding of PCa and EGF 1 0.05 1.42 0.8
110 INT108331 EGF Positive_regulation of Phosphorylation of BAD 1 0.49 6.72 0.8
111 INT150636 Binding of KNG1 and CD177 1 0.10 0.37 0.79
112 INT182814 Binding of ICAM1 and PECAM1 2 0.02 3.32 0.77
113 INT113546 Binding of FN1 and ITGA3 1 0.03 2.12 0.77
114 INT161485 Il1b Regulation of Gene_expression of TGFB1 1 0.47 1.21 0.77
115 INT161483 Slc7a12 Regulation of Gene_expression of TGFB1 1 0.14 1.21 0.77
116 INT129415 KNG1 Positive_regulation of Trpv1 1 0.05 0.39 0.76
117 INT161945 TGFB2 Positive_regulation of TGFBR1 1 0.08 0.99 0.76
118 INT107028 KNG1 Regulation of Des 1 0.01 1.7 0.76
119 INT161482 Il1b Negative_regulation of TGFB1 1 0.45 1.17 0.76
120 INT170127 Binding of ITGAL and PECAM1 2 0.01 2.71 0.75
121 INT176473 IL10 Positive_regulation of Gene_expression of PECAM1 1 0.05 1.1 0.75
122 INT250959 Binding of HLA-B and SOD1 1 0.05 0.75 0.75
123 INT309735 Binding of CALM3 and TRPV4 1 0.14 0 0.75
124 INT332699 Binding of KNG1 and TRGC1 1 0.16 3.37 0.75
125 INT161949 TGFB2 Positive_regulation of Gene_expression of Ngf 1 0.21 0.97 0.74
126 INT295711 MMP9 Positive_regulation of Localization of VEGFA 1 0.06 0.29 0.74
127 INT176479 IL17A Positive_regulation of Gene_expression of TIMP1 1 0.02 1.33 0.74
128 INT170992 Binding of FN1 and MMRN1 3 0.01 2.13 0.73
129 INT259556 PLEK Negative_regulation of Gene_expression of VEGFA 1 0.46 2.15 0.73
130 INT161484 Binding of TGFB1 and Il1b 1 0.37 1.16 0.73
131 INT259557 PLEK Negative_regulation of Positive_regulation of VEGFA 1 0.46 2.15 0.73
132 INT243169 EGFL7 Positive_regulation of Gene_expression of PPBP 1 0.02 0.67 0.72
133 INT296097 Acsm3 Negative_regulation of SOD1 1 0.01 1.3 0.72
134 INT220746 EGF Positive_regulation of Gene_expression of GOPC 1 0.13 0 0.72
135 INT196526 Binding of TIMP1 and TIMP2 1 0.45 1.49 0.71
136 INT187115 Binding of TIMP1 and TNF 2 0.30 1.07 0.7
137 INT120018 VEGFA Positive_regulation of CCL3 1 0.01 1 0.7
138 INT120020 VEGFA Positive_regulation of CCL2 1 0.00 1 0.7
139 INT99818 IFNG Positive_regulation of Gene_expression of APP 1 0.04 0.82 0.7
140 INT346267 Binding of HGF and IL6 1 0.04 0.96 0.7
141 INT81968 Binding of PLEK and Adra2a 1 0.07 0.1 0.7
142 INT120036 VEGFA Positive_regulation of Prap1 1 0.00 1 0.7
143 INT28947 GH1 Positive_regulation of Gene_expression of IGF1 4 0.22 3.78 0.69
144 INT34772 GH1 Regulation of IGF1 2 0.32 0.95 0.69
145 INT121458 KNG1 Positive_regulation of Localization of Trpv1 1 0.16 0.43 0.69
146 INT303691 KNG1 Positive_regulation of AHR 1 0.03 0.98 0.69
147 INT338693 Aff3 Positive_regulation of Localization of CAP1 1 0.01 0.39 0.69
148 INT303689 Regulation of KNG1 Positive_regulation of AHR 1 0.03 0.99 0.69
149 INT324900 VEGFA Positive_regulation of Gene_expression of Edn1 1 0.06 1.61 0.69
150 INT302642 Binding of ARSA and TGFB1 1 0.05 0.28 0.68
151 INT167355 VEGFA Regulation of RYBP 1 0.01 0.53 0.68
152 INT168295 PROC Regulation of Gene_expression of VEGFA 2 0.00 1.6 0.67
153 INT354913 VDR Positive_regulation of TGFB1 1 0.05 1.33 0.67
154 INT220738 EGF Regulation of Gene_expression of EGFR 1 0.09 0.6 0.67
155 INT220148 Binding of IGF1 and IGFBP3 12 0.36 5.56 0.66
156 INT214595 Binding of FOXC1 and TIMP1 1 0.02 0.96 0.66
157 INT209854 IL4 Positive_regulation of Gene_expression of CD36 1 0.51 1.2 0.65
158 INT136815 VEGFA Positive_regulation of Positive_regulation of RHOA 1 0.44 0.06 0.65
159 INT45369 IGF1 Regulation of GH1 1 0.04 1.12 0.65
160 INT95546 KNG1 Positive_regulation of Ptgir 1 0.02 0.93 0.64
161 INT92045 Binding of ALB and SERPINA1 1 0.30 1.37 0.64
162 INT322385 PPBP Negative_regulation of Positive_regulation of OPRM1 1 0.00 0 0.64
163 INT96472 KNG1 Positive_regulation of Gene_expression of TRPV1 1 0.01 0.22 0.64
164 INT99728 Binding of F13A1 and PLG 4 0.02 2.51 0.63
165 INT121713 WAS Positive_regulation of Gene_expression of SELP 1 0.30 0.49 0.63
166 INT34005 YY1 Regulation of KNG1 1 0.04 0.38 0.63
167 INT174860 VEGFA Positive_regulation of Localization of CCL2 1 0.21 1.68 0.63
168 INT333544 CTSB Regulation of Protein_catabolism of APP 1 0.01 0.53 0.62
169 INT121460 KNG1 Positive_regulation of Bdkrb2 1 0.08 0.44 0.62
170 INT182156 Binding of HGF and IL3RA 1 0.03 1.31 0.62
171 INT100369 HIF1A Positive_regulation of Positive_regulation of VEGFA 1 0.29 0.99 0.62
172 INT118083 Aip Negative_regulation of Phosphorylation of APP 1 0.00 0.75 0.62
173 INT121459 Bdkrb2 Positive_regulation of KNG1 1 0.09 0.44 0.62
174 INT333543 CTSB Regulation of APP 1 0.01 0.53 0.62
175 INT337323 KNG1 Positive_regulation of PRKCA 1 0.15 0.17 0.62
176 INT255690 Binding of VEGFA and Flt1 8 0.34 3.44 0.61
177 INT267625 Binding of KNG1 and Klk1 2 0.21 2.23 0.61
178 INT182819 Binding of CD63 and PECAM1 1 0.00 1.63 0.61
179 INT224731 Binding of VEGFA and Cia1 1 0.01 0.91 0.61
180 INT224733 Negative_regulation of Binding of VEGFA and Cia1 1 0.01 0.91 0.61
181 INT98629 VEGFA Positive_regulation of Gene_expression of EGR1 1 0.52 0.42 0.61
182 INT98628 VEGFA Positive_regulation of Transcription of EGR1 1 0.52 0.42 0.61
183 INT182815 Binding of CD63 and ICAM1 1 0.00 1.63 0.61
184 INT169287 EGF Positive_regulation of Localization of IL8 1 0.15 0.13 0.61
185 INT284089 Binding of NTRK2 and SERPINE1 1 0.27 0.73 0.61
186 INT34840 Binding of KNG1 and PDYN 1 0.01 0 0.61
187 INT169294 EGF Positive_regulation of Localization of IL6 1 0.18 0.13 0.61
188 INT145661 Ptger2 Positive_regulation of Gene_expression of VEGFA 4 0.27 2.73 0.6
189 INT193290 CAP1 Regulation of Fth1 1 0.02 0 0.6
190 INT193265 CAP1 Regulation of STH 1 0.00 0 0.6
191 INT299286 VEGFA Positive_regulation of PI3 1 0.16 0.46 0.6
192 INT193289 CAP1 Regulation of Pth 1 0.02 0 0.59
193 INT202971 Binding of BAG3 and CAP1 1 0.04 1.26 0.59
194 INT202973 Binding of CAP1 and CPP 1 0.05 1.24 0.58
195 INT181619 ACE Positive_regulation of KNG1 1 0.33 0.97 0.58
196 INT202970 Binding of STC2 and CAP1 1 0.00 1.25 0.58
197 INT342624 VEGFA Negative_regulation of Mmp2 1 0.09 1.54 0.58
198 INT327339 Gtf3a Positive_regulation of VEGFA 1 0.00 2.34 0.58
199 INT120347 Binding of KNG1 and MYC 1 0.21 0.17 0.58
200 INT199976 EGF Regulation of ITGB3BP 1 0.02 0.77 0.57

Single Events

The table below shows the top 100 pain related interactions that have been reported for platelet degranulation. They are ordered first by their pain relevance and then by number of times they were reported in platelet degranulation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2
2 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65
3 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73
4 INT8357 Gene_expression of KNG1 153 0.75 77.26 68.66
5 INT7134 Localization of KNG1 127 0.79 65.73 67.97
6 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07
7 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18
8 INT546 Binding of ALB 311 0.48 85.98 60.14
9 INT1759 Gene_expression of TIMP1 267 0.77 133.87 59.29
10 INT11491 Positive_regulation of KNG1 128 0.67 60.41 58.74
11 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53
12 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75
13 INT63349 Gene_expression of PECAM1 199 0.75 166.03 36.76
14 INT12892 Negative_regulation of TIMP1 136 0.58 83.13 36.54
15 INT101992 Localization of VEGFA 413 0.81 258.23 36.15
16 INT84825 Gene_expression of CD36 121 0.78 43.73 33.23
17 INT48693 Regulation of VEGFA 268 0.62 191.88 31.52
18 INT608 Negative_regulation of KNG1 98 0.43 72.36 31.23
19 INT99688 Negative_regulation of Gene_expression of VEGFA 274 0.58 201.8 31.1
20 INT8097 Gene_expression of EGF 122 0.77 75.94 28.47
21 INT11361 Gene_expression of SERPINE1 183 0.78 136.45 27.97
22 INT3076 Regulation of KNG1 52 0.60 20.39 27.89
23 INT9296 Negative_regulation of PLEK 100 0.57 36.65 27.52
24 INT3167 Binding of KNG1 48 0.48 23.26 26.77
25 INT3760 Positive_regulation of ALB 142 0.70 87.46 26.7
26 INT9682 Positive_regulation of IGF1 238 0.70 120.03 26.36
27 INT62710 Gene_expression of HGF 160 0.78 88.27 26.14
28 INT44954 Gene_expression of APP 191 0.78 105.86 23.9
29 INT14731 Positive_regulation of TGFB1 78 0.67 52.57 22.23
30 INT14733 Positive_regulation of Gene_expression of TGFB1 71 0.69 49.89 22.2
31 INT9079 Gene_expression of PPBP 52 0.75 31.2 21.52
32 INT48692 Binding of VEGFA 345 0.48 210.3 21.31
33 INT11157 Binding of EGF 88 0.48 53.73 21.25
34 INT68683 Regulation of Gene_expression of VEGFA 143 0.62 104.19 20.14
35 INT51055 Positive_regulation of TIMP1 103 0.69 50.07 19.86
36 INT14737 Gene_expression of FN1 117 0.78 78.74 18.99
37 INT28951 Negative_regulation of IGF1 133 0.59 75.77 18.9
38 INT3952 Negative_regulation of ALB 116 0.59 72.18 18.35
39 INT12081 Localization of TGFB1 64 0.81 35.4 17.47
40 INT68681 Transcription of VEGFA 132 0.71 80.47 17.03
41 INT23657 Positive_regulation of APP 64 0.70 39.76 16.68
42 INT28950 Positive_regulation of Gene_expression of IGF1 99 0.69 46.9 16.47
43 INT899 Gene_expression of F13A1 122 0.70 78.02 16.26
44 INT1888 Protein_catabolism of F13A1 97 0.99 63.48 14.82
45 INT11636 Positive_regulation of SERPINE1 85 0.69 68.73 14.8
46 INT88544 Gene_expression of MMRN1 102 0.75 68.8 14.55
47 INT72127 Protein_catabolism of MMRN1 68 0.52 56 14.13
48 INT1758 Positive_regulation of Gene_expression of TIMP1 62 0.69 31.72 13.98
49 INT18773 Localization of ALB 117 0.80 69.18 13.8
50 INT27739 Positive_regulation of EGF 49 0.70 28.31 13.68
51 INT11071 Positive_regulation of PPBP 43 0.68 26.85 13.43
52 INT142621 Positive_regulation of Gene_expression of CD36 38 0.70 15.18 13.4
53 INT31990 Positive_regulation of SOD1 124 0.69 67.79 12.52
54 INT12135 Gene_expression of PLEK 62 0.75 34.13 12.47
55 INT14510 Gene_expression of SOD1 208 0.76 88.56 12.4
56 INT29745 Binding of APP 47 0.48 26.49 12.4
57 INT28952 Negative_regulation of Gene_expression of IGF1 75 0.58 41.11 12.32
58 INT55687 Localization of TIMP1 47 0.74 30.24 12.31
59 INT61946 Positive_regulation of HGF 57 0.69 38.93 11.99
60 INT4047 Binding of F13A1 105 0.43 66.54 11.81
61 INT49142 Gene_expression of SELP 94 0.75 54.61 11.64
62 INT14204 Protein_catabolism of KNG1 41 0.96 20.94 11.47
63 INT13240 Gene_expression of TF 94 0.76 57.81 10.99
64 INT18412 Binding of PLEK 49 0.47 17.82 10.72
65 INT10049 Negative_regulation of SERPINA1 56 0.59 44.52 9.93
66 INT2378 Negative_regulation of SERPINE1 47 0.59 34.55 9.9
67 INT2036 Localization of EGF 42 0.77 21.5 9.74
68 INT11729 Regulation of IGF1 71 0.61 44.58 9.71
69 INT4391 Gene_expression of SERPINA1 47 0.78 41.43 9.7
70 INT10139 Positive_regulation of F13A1 64 0.56 44.75 9.69
71 INT68373 Negative_regulation of FLNA 59 0.57 60.46 9.55
72 INT3366 Localization of PLEK 44 0.78 15.83 9.55
73 INT11679 Negative_regulation of F13A1 55 0.54 33.69 9.43
74 INT41569 Regulation of APP 32 0.62 17.15 9.4
75 INT93309 Positive_regulation of CAP1 17 0.43 11.4 9.13
76 INT860 Regulation of ALB 48 0.60 25.11 8.95
77 INT34777 Localization of IGF1 82 0.80 42.68 8.62
78 INT93310 Gene_expression of CAP1 14 0.58 3.07 8.55
79 INT16460 Negative_regulation of PPBP 21 0.57 13.86 8.54
80 INT209866 Regulation of Gene_expression of CD36 27 0.60 10.04 8.42
81 INT70896 Gene_expression of PDGFB 48 0.65 33.55 8.39
82 INT10969 Positive_regulation of PLEK 33 0.67 16.96 8.35
83 INT12975 Regulation of PLEK 21 0.60 13.62 8.28
84 INT60034 Positive_regulation of VWF 40 0.68 30.42 8.15
85 INT26551 Positive_regulation of Gene_expression of KNG1 19 0.67 11.05 7.98
86 INT36678 Binding of TIMP1 33 0.36 14.99 7.87
87 INT14732 Positive_regulation of FN1 46 0.69 31.17 7.33
88 INT84932 Negative_regulation of APP 29 0.57 28.45 7.2
89 INT16618 Negative_regulation of SERPING1 81 0.59 86.28 7.17
90 INT21579 Negative_regulation of Gene_expression of TIMP1 25 0.57 12.41 6.94
91 INT14903 Negative_regulation of SOD1 81 0.57 42.02 6.91
92 INT95117 Gene_expression of PDGFA 71 0.71 51.17 6.9
93 INT3757 Positive_regulation of Gene_expression of ALB 45 0.69 23.73 6.85
94 INT2037 Negative_regulation of EGF 30 0.59 15.05 6.81
95 INT74944 Positive_regulation of Gene_expression of HGF 31 0.70 17.69 6.68
96 INT86805 Localization of HGF 49 0.71 28.48 6.35
97 INT142065 Phosphorylation of CFL1 8 0.78 0.87 6.3
98 INT4561 Gene_expression of PLG 32 0.75 17.59 6.21
99 INT5146 Localization of PPBP 32 0.81 12.5 6.08
100 INT117621 Positive_regulation of HSPA5 17 0.59 13.26 6.06
101 INT34232 Regulation of TIMP1 37 0.61 18.76 6.05
102 INT111545 Phosphorylation of VEGFA 50 0.76 22.19 5.88
103 INT131378 Negative_regulation of FN1 20 0.35 33.98 5.85
104 INT97018 Binding of CALM3 7 0.43 0.13 5.82
105 INT86111 Positive_regulation of Positive_regulation of VEGFA 38 0.69 33.81 5.78
106 INT63351 Negative_regulation of Gene_expression of PECAM1 19 0.52 16.06 5.73
107 INT21647 Negative_regulation of Positive_regulation of KNG1 11 0.43 5.54 5.73
108 INT11360 Localization of SERPINE1 41 0.80 33.98 5.61
109 INT32458 Gene_expression of VWF 57 0.78 28.97 5.56
110 INT187133 Protein_catabolism of TIMP1 19 0.73 11.3 5.51
111 INT11480 Positive_regulation of Localization of KNG1 15 0.30 6.39 5.5
112 INT164656 Negative_regulation of Gene_expression of CD36 24 0.57 6.51 5.39
113 INT49801 Positive_regulation of SELP 21 0.48 21.34 5.25
114 INT22597 Positive_regulation of TF 43 0.68 27.27 5.17
115 INT37227 Regulation of EGF 19 0.45 11.16 5.17
116 INT89104 Binding of TGFB1 29 0.44 13.67 5.12
117 INT99823 Positive_regulation of Gene_expression of APP 31 0.70 21.52 5.09
118 INT115816 Protein_catabolism of APP 35 0.99 20.14 5.06
119 INT30738 Negative_regulation of Gene_expression of ALB 32 0.59 19.01 5.04
120 INT3647 Positive_regulation of Gene_expression of F13A1 20 0.41 15.71 5.02
121 INT17489 Regulation of F13A1 28 0.45 15.79 4.93
122 INT105393 Positive_regulation of Localization of VEGFA 66 0.70 45.45 4.9
123 INT10138 Negative_regulation of Gene_expression of KNG1 13 0.57 9.57 4.9
124 INT16214 Localization of F13A1 36 0.74 21.8 4.87
125 INT12104 Positive_regulation of PLG 45 0.68 28.94 4.81
126 INT113948 Gene_expression of FLNA 32 0.73 36.06 4.81
127 INT99690 Negative_regulation of Positive_regulation of VEGFA 30 0.58 14.56 4.79
128 INT21582 Regulation of Gene_expression of TIMP1 20 0.61 12.39 4.77
129 INT144481 Gene_expression of SERPING1 55 0.77 50.4 4.75
130 INT170854 Gene_expression of CFD 26 0.68 39.77 4.74
131 INT82354 Positive_regulation of PECAM1 25 0.34 22.93 4.69
132 INT87632 Positive_regulation of Gene_expression of PECAM1 32 0.45 29.47 4.66
133 INT11354 Regulation of Gene_expression of SERPINE1 11 0.61 8.66 4.42
134 INT74531 Regulation of PDGFB 14 0.26 7.57 4.38
135 INT89103 Regulation of Gene_expression of TGFB1 15 0.56 8.11 4.37
136 INT9080 Regulation of PPBP 17 0.44 5.75 4.3
137 INT39948 Binding of FLNA 45 0.42 58.05 4.27
138 INT11635 Positive_regulation of Gene_expression of SERPINE1 35 0.68 24.57 4.26
139 INT11634 Regulation of SERPINE1 24 0.62 20.06 4.26
140 INT103153 Positive_regulation of Transcription of VEGFA 34 0.69 22.16 4.22
141 INT51898 Binding of PECAM1 26 0.36 18.87 4.22
142 INT58003 Localization of APP 32 0.80 13.75 4.2
143 INT57273 Positive_regulation of Gene_expression of FN1 26 0.47 17.83 4.2
144 INT49217 Positive_regulation of Positive_regulation of KNG1 7 0.41 3.64 4.18
145 INT156097 Negative_regulation of Localization of VEGFA 70 0.58 34.96 4.17
146 INT88545 Localization of MMRN1 21 0.78 16.67 4.01
147 INT63880 Positive_regulation of FLNA 29 0.59 13.88 3.97
148 INT99821 Negative_regulation of Gene_expression of APP 20 0.42 15.21 3.94
149 INT51831 Negative_regulation of ITGA2B 20 0.57 10.59 3.91
150 INT44323 Positive_regulation of F8 32 0.60 24.88 3.89
151 INT51312 Positive_regulation of Gene_expression of SERPINA1 4 0.46 9.41 3.84
152 INT38033 Regulation of HGF 26 0.45 14.96 3.81
153 INT124655 Negative_regulation of PECAM1 13 0.23 10.32 3.78
154 INT120596 Gene_expression of ABCC4 11 0.78 2.51 3.76
155 INT146946 Gene_expression of Lyn 16 0.76 8.9 3.75
156 INT142066 Positive_regulation of Phosphorylation of CFL1 5 0.48 0.24 3.73
157 INT52227 Gene_expression of CD9 11 0.75 6.23 3.71
158 INT99819 Negative_regulation of Positive_regulation of APP 6 0.58 4.41 3.64
159 INT137702 Binding of TTN 7 0.35 4.48 3.62
160 INT33739 Gene_expression of ITGA2B 25 0.75 8.19 3.6
161 INT12083 Regulation of TGFB1 22 0.53 15.4 3.6
162 INT51848 Transcription of TGFB1 17 0.69 9.57 3.53
163 INT193281 Binding of CAP1 7 0.07 4.57 3.53
164 INT70897 Positive_regulation of Gene_expression of PDGFB 15 0.57 13.04 3.52
165 INT56300 Negative_regulation of Gene_expression of TGFB1 13 0.41 4.87 3.5
166 INT26702 Transcription of CD36 17 0.70 3.56 3.49
167 INT63425 Positive_regulation of Gene_expression of SELP 23 0.67 15.34 3.48
168 INT8096 Positive_regulation of Gene_expression of EGF 21 0.69 13.43 3.47
169 INT70089 Negative_regulation of Binding of APP 7 0.59 6.45 3.44
170 INT220078 Positive_regulation of Negative_regulation of KNG1 3 0.13 5.03 3.41
171 INT70895 Localization of PDGFB 20 0.52 8.98 3.4
172 INT74946 Negative_regulation of Gene_expression of HGF 14 0.58 6.29 3.39
173 INT190208 Positive_regulation of MMRN1 15 0.23 14.1 3.37
174 INT3881 Positive_regulation of Protein_catabolism of F13A1 21 0.41 20 3.28
175 INT55690 Positive_regulation of Localization of TIMP1 8 0.50 4.77 3.28
176 INT22375 Localization of PDGFA 21 0.75 15.46 3.25
177 INT99687 Negative_regulation of Transcription of VEGFA 17 0.43 10.3 3.25
178 INT111547 Negative_regulation of Phosphorylation of VEGFA 13 0.42 5.08 3.22
179 INT61500 Binding of FN1 39 0.48 27.33 3.13
180 INT55409 Localization of VWF 17 0.80 8.99 3.06
181 INT131187 Regulation of Gene_expression of IGF1 18 0.62 11.18 3.05
182 INT19293 Protein_catabolism of FN1 7 0.95 5.15 2.97
183 INT14872 Gene_expression of TGFB3 15 0.55 12.45 2.96
184 INT16130 Binding of IGF1 67 0.48 27.43 2.95
185 INT91432 Binding of MMRN1 23 0.36 9.79 2.95
186 INT59719 Localization of SELP 12 0.78 8.4 2.95
187 INT9130 Negative_regulation of TGFB1 16 0.41 12.21 2.92
188 INT117785 Regulation of Gene_expression of EGF 7 0.44 4.22 2.87
189 INT10893 Binding of VWF 27 0.47 25.02 2.82
190 INT130700 Gene_expression of HSPA5 16 0.75 11.55 2.81
191 INT91319 Positive_regulation of CD63 6 0.63 3.86 2.76
192 INT10141 Gene_expression of A2M 11 0.35 9.37 2.75
193 INT100360 Negative_regulation of TF 19 0.42 10.43 2.68
194 INT130702 Positive_regulation of Gene_expression of HSPA5 7 0.59 7.53 2.68
195 INT21712 Positive_regulation of APOA1 32 0.67 21.64 2.64
196 INT83642 Gene_expression of CD63 22 0.77 10.06 2.63
197 INT111298 Gene_expression of ACTN4 12 0.70 9.42 2.6
198 INT99550 Regulation of FLNA 51 0.54 27.88 2.58
199 INT146931 Regulation of CAP1 1 0.44 0.22 2.58
200 INT25449 Positive_regulation of Gene_expression of PPBP 5 0.46 3.77 2.57
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