GO:0002675

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Name positive regulation of acute inflammatory response
Categary Process
Go Slim No
Go Link GO:0002675
Unique Molecular Interactions 1092
Total Molecular Interactions 1662
Total Single Events 14548
Pain Genes Associated 16

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of acute inflammatory response. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of acute inflammatory response. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT254001 Binding of Cxcr4 and Mif 1 0.52 14.17 7.18
2 INT79759 Ngf Regulation of Il6 1 0.60 4.62 5.62
3 INT126335 Binding of Pax3 and Tac1 6 0.07 6.22 5.27
4 INT64718 IL1B Positive_regulation of Gene_expression of IL6 15 0.59 9.37 4.48
5 INT132228 Negative_regulation of Binding of Pik3cg and Sh2d6 1 0.07 1.96 3.6
6 INT132231 Negative_regulation of Binding of Akt1 and Pik3cg 1 0.34 1.96 3.6
7 INT57985 Il1b Positive_regulation of Il6 5 0.59 1.66 3.53
8 INT91271 Mtr Regulation of Gene_expression of Il6 1 0.20 0 3.17
9 INT64719 IL1B Positive_regulation of IL6 7 0.41 6.84 3.14
10 INT150888 Il1a Regulation of Il6 1 0.10 3.47 2.93
11 INT86180 SFTPA1 Positive_regulation of Localization of IL6 2 0.06 2.01 2.85
12 INT222522 Il1a Positive_regulation of Gene_expression of Il6 2 0.06 1.79 2.79
13 INT154187 Il6 Positive_regulation of Gene_expression of Cd2 1 0.08 3.07 2.71
14 INT154188 Il6 Positive_regulation of Gene_expression of Atf3 1 0.76 3.07 2.71
15 INT253988 Binding of Cd74 and Mif 1 0.36 6.57 2.52
16 INT294909 Pax3 Positive_regulation of Gene_expression of Il6 1 0.09 5.43 2.51
17 INT115367 Binding of IL6 and IL6R 12 0.07 8.16 2.36
18 INT124121 IL6 Positive_regulation of CCL2 1 0.26 1.84 2.25
19 INT96652 F2rl1 Positive_regulation of Tac1 1 0.47 2.62 2.25
20 INT126717 Binding of Il6 and Il6st 3 0.21 3.35 2.22
21 INT124120 IL6 Regulation of CCL2 1 0.15 1.8 2.22
22 INT94492 Il6 Positive_regulation of Gene_expression of Il1b 1 0.27 3.81 2.19
23 INT94504 Il6 Positive_regulation of Gene_expression of Tnf 1 0.30 3.8 2.19
24 INT94494 Il1b Positive_regulation of Gene_expression of Il6 1 0.27 3.81 2.19
25 INT86179 TNF Positive_regulation of Localization of IL6 5 0.35 1.66 2.17
26 INT135035 Binding of Hk1 and Tac1 1 0.35 0.18 2.14
27 INT126400 ITIH4 Positive_regulation of Gene_expression of Il6 1 0.00 2.11 2.08
28 INT70043 IL6 Regulation of IL10 3 0.18 3.59 2.01
29 INT164784 Il6 Positive_regulation of Gene_expression of Cx3cr1 1 0.47 2.37 1.98
30 INT278937 LEP Positive_regulation of Gene_expression of IL6 1 0.32 3.42 1.97
31 INT156509 Il6 Regulation of Positive_regulation of Grin1 1 0.28 1.93 1.93
32 INT102130 Il6 Positive_regulation of Gene_expression of Crp 4 0.05 7.39 1.91
33 INT24942 Calca Regulation of TAC1 1 0.13 0.7 1.89
34 INT51051 IL1B Positive_regulation of Localization of IL6 7 0.57 3.79 1.87
35 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87
36 INT203149 Binding of Mif and Osm 1 0.02 2.93 1.78
37 INT89379 TNF Positive_regulation of Gene_expression of IL6 5 0.50 4.37 1.69
38 INT213071 IL6 Positive_regulation of Gene_expression of CRP 4 0.52 6.58 1.68
39 INT169441 TAC1 Positive_regulation of Tac1 1 0.01 1.7 1.64
40 INT147258 Binding of Tac1 and Penk 1 0.35 0 1.64
41 INT160578 Binding of CALCA and TAC1 1 0.07 0.91 1.61
42 INT158774 Mapk14 Regulation of Il6 1 0.11 0.08 1.57
43 INT76651 Cpe Positive_regulation of Gene_expression of Il6 1 0.08 0 1.56
44 INT182097 Binding of Il6 and Il1 4 0.07 4.67 1.55
45 INT73016 PDYN Regulation of TAC1 1 0.29 0.34 1.54
46 INT135276 Gt(pU21)50Imeg Negative_regulation of Gene_expression of Il6 1 0.02 0.52 1.52
47 INT76656 POMC Positive_regulation of Gene_expression of Il6 1 0.03 0 1.51
48 INT126718 Binding of Il6 and Il6r 3 0.09 2.33 1.49
49 INT150885 Il6 Regulation of Il10 1 0.22 1.74 1.47
50 INT285569 TNF Negative_regulation of Gene_expression of Il6 1 0.03 2.83 1.46
51 INT155371 VIP Positive_regulation of Localization of IL6 1 0.64 3.37 1.44
52 INT236365 Binding of CD40LG and IL6 3 0.20 4.16 1.42
53 INT172834 Binding of IL6 and T2dm2 1 0.00 6.4 1.4
54 INT71543 IFNA1 Negative_regulation of Positive_regulation of TAC1 1 0.20 0.19 1.4
55 INT329452 Binding of Tac1 and Oprd1 1 0.01 0.23 1.4
56 INT223156 Il6 Regulation of A2m 1 0.11 2.79 1.39
57 INT51160 Binding of TAC1 and Tacr1 2 0.28 0.55 1.38
58 INT218309 Binding of CRP and IL6 3 0.23 4.78 1.36
59 INT177457 Il1 Positive_regulation of Gene_expression of Il6 3 0.16 4.47 1.35
60 INT15277 Binding of Tac1 and Gal 1 0.39 0.19 1.35
61 INT160586 IL6 Positive_regulation of Gene_expression of OPRM1 1 0.14 0.54 1.35
62 INT185330 Binding of Hrh1 and Tac1 1 0.00 0.1 1.34
63 INT136603 Calca Positive_regulation of Localization of Il6 1 0.67 0.78 1.32
64 INT182096 Positive_regulation of Binding of Il6 and Il1 2 0.09 4.26 1.31
65 INT49231 TAC1 Negative_regulation of Penk 1 0.00 0 1.3
66 INT138213 Mzb1 Regulation of Localization of Tac1 1 0.01 0.41 1.29
67 INT138214 Mzb1 Regulation of Tac1 1 0.01 0.41 1.28
68 INT70226 Binding of TAC1 and B3GAT1 4 0.24 4.5 1.26
69 INT78066 Tlr4 Positive_regulation of Localization of Il6 5 0.03 0.76 1.25
70 INT121190 KCNMA1 Positive_regulation of Gene_expression of IL6 1 0.03 0.54 1.24
71 INT121189 KCNMA1 Positive_regulation of IL6 1 0.04 0.54 1.23
72 INT253999 Binding of Cxcl12 and Mif 1 0.41 2.26 1.22
73 INT70033 IL6 Regulation of PRF1 1 0.03 1.42 1.21
74 INT70047 IL6 Regulation of Negative_regulation of PRF1 1 0.03 1.42 1.21
75 INT70029 IL6 Regulation of Negative_regulation of IL10 1 0.05 1.42 1.21
76 INT353338 F2r Positive_regulation of Localization of Mif 1 0.68 1.25 1.16
77 INT195117 Ptgs2 Positive_regulation of Gene_expression of Il6 1 0.10 3.26 1.16
78 INT48809 Pax3 Negative_regulation of Binding of Tac1 1 0.22 0 1.16
79 INT185321 Tlr4 Positive_regulation of Gene_expression of Il6 5 0.14 1.97 1.15
80 INT290667 Il6 Positive_regulation of Stat3 3 0.69 2.42 1.15
81 INT94490 Il6 Positive_regulation of Gene_expression of Avp 1 0.33 1.97 1.15
82 INT94508 Il6 Positive_regulation of Gene_expression of AVP 1 0.42 1.96 1.14
83 INT294911 Pax3 Positive_regulation of Il6 1 0.06 1.78 1.14
84 INT94496 Il6 Positive_regulation of Gene_expression of Crh 1 0.29 1.94 1.12
85 INT294710 CRP Positive_regulation of Gene_expression of IL6 1 0.63 1.9 1.12
86 INT83616 Binding of IL6 and IL8 5 0.09 5.8 1.11
87 INT267588 IL10 Negative_regulation of Gene_expression of IL6 1 0.01 2.25 1.11
88 INT223154 Negative_regulation of Mapk14 Negative_regulation of Localization of Il6 1 0.19 1.13 1.11
89 INT113540 Binding of OPRM1 and Tac1 1 0.04 0.1 1.1
90 INT223157 Abat Negative_regulation of Localization of Il6 1 0.05 1.13 1.1
91 INT94495 Tnf Positive_regulation of Gene_expression of Il6 1 0.30 1.9 1.09
92 INT314136 Binding of TAC1 and SFTPA1 2 0.03 0.78 1.06
93 INT57986 Il1b Regulation of Positive_regulation of Il6 2 0.39 0.23 1.05
94 INT120316 Ghrh Regulation of Il6 1 0.11 0.95 1.05
95 INT120310 Ghrh Regulation of Positive_regulation of Il6 1 0.18 0.95 1.05
96 INT8416 LIF Regulation of TAC1 1 0.13 0.36 1.04
97 INT61617 PTGER2 Regulation of Gene_expression of IL6 3 0.11 1.13 1.02
98 INT87025 ZAK Positive_regulation of Gene_expression of IL6 2 0.11 1.59 1.02
99 INT218310 IL6 Positive_regulation of Localization of CRP 1 0.29 3.33 1.02
100 INT84959 Negative_regulation of Tacr1 Negative_regulation of Positive_regulation of Tac1 1 0.48 0.59 1.02
101 INT206074 Binding of IL6 and IL6ST 7 0.32 3.79 1.01
102 INT278946 IL6 Regulation of Gene_expression of IL8 1 0.20 1.9 1
103 INT86181 SFTPA1 Positive_regulation of IL6 1 0.07 0.32 0.99
104 INT244133 DDB1 Positive_regulation of Gene_expression of IL6 1 0.01 1.91 0.99
105 INT154254 Tnf Positive_regulation of Il6 1 0.36 0.94 0.97
106 INT114320 TNF Positive_regulation of Gene_expression of Il6 1 0.07 1.73 0.97
107 INT272984 Il6 Positive_regulation of Gene_expression of Itgam 1 0.24 0.78 0.96
108 INT163390 Il6 Positive_regulation of Gene_expression of Crp 2 0.03 3.42 0.95
109 INT107951 Pax3 Positive_regulation of Tac1 1 0.11 1.21 0.95
110 INT314142 Binding of TAC1 and Tacr3 1 0.06 0.73 0.94
111 INT299988 IL6 Positive_regulation of Localization of IL8 1 0.05 0.81 0.94
112 INT182024 TNF Positive_regulation of Gene_expression of Il6 1 0.05 1.58 0.94
113 INT24938 TAC1 Regulation of Calca 1 0.22 0.35 0.94
114 INT285418 IRF6 Positive_regulation of Localization of IL6 3 0.05 0.66 0.93
115 INT134785 Il2rb Regulation of Gene_expression of IL6 1 0.00 1.16 0.92
116 INT134784 Il2rb Regulation of IL6 1 0.00 1.16 0.92
117 INT78062 Il1a Positive_regulation of Localization of Il6 3 0.24 0.48 0.9
118 INT64717 Pomc Positive_regulation of Il6 1 0.13 0.19 0.9
119 INT132226 Binding of Akt1 and Pik3cg 1 0.30 0.49 0.9
120 INT40636 Mif Negative_regulation of Pomc 1 0.25 0.07 0.9
121 INT132227 Binding of Pik3cg and Sh2d6 1 0.06 0.49 0.9
122 INT91270 Oprd1 Regulation of Gene_expression of Il6 1 0.00 0 0.89
123 INT159962 Rock2 Regulation of Localization of Il6 1 0.09 2.7 0.88
124 INT91273 Mtr Positive_regulation of Localization of Il6 1 0.17 0 0.88
125 INT253992 Cxcl12 Positive_regulation of Mif 1 0.46 1.31 0.88
126 INT91272 Ifng Positive_regulation of Localization of Il6 1 0.29 0 0.88
127 INT24940 TAC1 Regulation of Nka1 1 0.10 0.34 0.87
128 INT231716 Binding of IL6 and DIP 1 0.24 1.55 0.87
129 INT339318 Ngf Positive_regulation of Pik3cg 1 0.02 0.69 0.87
130 INT203148 Mif Positive_regulation of Gene_expression of S100a8 1 0.00 1.56 0.87
131 INT76652 Cpe Positive_regulation of Il6 1 0.08 0 0.87
132 INT188214 OSM Regulation of MAPK1 1 0.20 2.27 0.87
133 INT199499 Il6 Positive_regulation of Transcription of Oprm1 1 0.01 0.8 0.86
134 INT199492 Il6 Positive_regulation of Transcription of Oprm1 1 0.01 0.81 0.86
135 INT199487 Il6 Positive_regulation of Oprm1 1 0.01 0.8 0.86
136 INT199491 Il6 Positive_regulation of Positive_regulation of Il6 1 0.00 0.81 0.86
137 INT199500 Il6 Positive_regulation of Oprm1 1 0.01 0.8 0.85
138 INT342986 PTAFR Positive_regulation of Gene_expression of IL6 1 0.14 0.39 0.84
139 INT54992 Il6 Negative_regulation of Prl 1 0.00 0.86 0.84
140 INT105435 TNF Positive_regulation of IL6 5 0.25 4.45 0.83
141 INT86430 IL6 Positive_regulation of Gene_expression of HP 1 0.15 3.61 0.83
142 INT195217 EGFL7 Negative_regulation of Gene_expression of IL6 1 0.06 1.14 0.83
143 INT342999 IL6 Positive_regulation of Gene_expression of HIST2H2AA3 1 0.00 0.4 0.83
144 INT306271 IL1A Positive_regulation of Gene_expression of IL6 1 0.30 0.85 0.8
145 INT135278 Gt(pU21)50Imeg Negative_regulation of Positive_regulation of Il6 1 0.02 0.26 0.8
146 INT160411 Tat Positive_regulation of Il6 1 0.17 0.89 0.8
147 INT132977 Tac1 Positive_regulation of Mapk1 1 0.06 0.17 0.79
148 INT135277 Gt(pU21)50Imeg Negative_regulation of Il6 1 0.02 0.23 0.78
149 INT196577 Negative_regulation of Mapk14 Negative_regulation of Il6 1 0.13 0.45 0.78
150 INT213978 Binding of TAC1 and Tac1 1 0.02 0.36 0.78
151 INT196574 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Il6 1 0.13 0.45 0.78
152 INT296792 Tlr9 Regulation of Gene_expression of Il6 1 0.06 1.36 0.76
153 INT178579 CNTN2 Positive_regulation of IL6 1 0.07 2.17 0.75
154 INT142847 IRF6 Positive_regulation of IL6 5 0.07 1.09 0.73
155 INT248271 IL6 Regulation of Gene_expression of Crp 3 0.27 1.7 0.73
156 INT331599 Tlr9 Positive_regulation of Gene_expression of Il6 1 0.03 1.8 0.73
157 INT124352 Il6 Positive_regulation of Positive_regulation of Gorasp2 1 0.10 1.19 0.73
158 INT327994 Il6 Positive_regulation of Gene_expression of ROS1 1 0.05 0.55 0.73
159 INT172134 Binding of IL6 and IL15 2 0.01 1.18 0.72
160 INT237325 Il6 Positive_regulation of Gene_expression of Ik 2 0.00 2.09 0.72
161 INT209057 Il6 Positive_regulation of Csf2 1 0.03 0.38 0.72
162 INT209039 Il6 Positive_regulation of Il17a 1 0.05 0.38 0.72
163 INT209056 Il6 Positive_regulation of Elf1 1 0.10 0.38 0.72
164 INT209059 Il6 Positive_regulation of Cxcl1 1 0.06 0.38 0.72
165 INT150996 Sfpq Positive_regulation of Gene_expression of Il6 1 0.04 0.7 0.72
166 INT236364 CD40LG Positive_regulation of Gene_expression of IL6 1 0.25 1.37 0.72
167 INT209060 Il6 Positive_regulation of Ccr1 1 0.01 0.38 0.72
168 INT51005 PDYN Positive_regulation of IL6 1 0.08 0.84 0.72
169 INT260551 Igh-Dex Negative_regulation of Il6 1 0.09 0.37 0.72
170 INT73822 TAC1 Positive_regulation of Localization of IL1B 1 0.04 0.56 0.71
171 INT159963 Tnf Positive_regulation of Localization of Il6 1 0.12 2.32 0.71
172 INT89936 Tlr4 Positive_regulation of Il6 3 0.49 0.95 0.7
173 INT40703 Mif Negative_regulation of Negative_regulation of POMC 1 0.24 0.49 0.7
174 INT91700 Il6 Negative_regulation of Oprd1 1 0.23 0 0.7
175 INT346267 Binding of HGF and IL6 1 0.04 0.96 0.7
176 INT215098 Tlr4 Positive_regulation of Localization of Il6 3 0.18 1.18 0.69
177 INT278968 LEP Regulation of Gene_expression of IL6 1 0.29 1.11 0.69
178 INT253994 Cyp3a23/3a1 Positive_regulation of Localization of Mif 1 0.09 0.96 0.69
179 INT150998 Sfpq Negative_regulation of Gene_expression of Il6 1 0.05 0.69 0.69
180 INT325270 Il33 Positive_regulation of Gene_expression of Il6 1 0.20 1.59 0.69
181 INT76655 POMC Positive_regulation of Transcription of Il6 1 0.01 0 0.68
182 INT76654 Cpe Positive_regulation of Transcription of Il6 1 0.05 0 0.68
183 INT79937 TAC1 Positive_regulation of Gene_expression of VCAM1 1 0.20 0.15 0.68
184 INT203758 Binding of IL6 and TNF 3 0.26 2.03 0.67
185 INT278953 IL6 Regulation of Gene_expression of PTGER2 1 0.04 1.38 0.67
186 INT102350 P2rx1 Negative_regulation of Localization of Il6 1 0.32 0 0.67
187 INT109718 Tac1 Negative_regulation of Mpo 1 0.25 0.81 0.67
188 INT147257 Tac1 Regulation of Penk 1 0.19 0 0.67
189 INT164782 Il6 Regulation of Gene_expression of Cx3cr1 1 0.27 0.79 0.67
190 INT320152 IL6 Positive_regulation of IL1RN 2 0.23 2.59 0.66
191 INT82384 Penk Positive_regulation of Gene_expression of Il6 1 0.15 0 0.66
192 INT285943 IL17A Positive_regulation of Localization of IL6 3 0.20 2.02 0.65
193 INT121812 IL6 Regulation of OPRM1 1 0.22 0.27 0.65
194 INT190178 PIK3CG Regulation of MMP12 1 0.09 0 0.65
195 INT209054 Il17a Positive_regulation of Gene_expression of Il6 1 0.10 0.45 0.65
196 INT191494 IL6 Positive_regulation of Binding of CRP 1 0.02 1.65 0.65
197 INT111937 Binding of PIK3CG and PTK2 1 0.08 0.67 0.64
198 INT209055 S100a8 Positive_regulation of Gene_expression of Il6 1 0.01 0.45 0.64
199 INT63655 Binding of NPY and TAC1 1 0.39 0.17 0.64
200 INT64956 IRF6 Positive_regulation of Gene_expression of IL6 4 0.19 1.4 0.63

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of acute inflammatory response. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of acute inflammatory response. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22
2 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57
3 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57
4 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59
5 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38
6 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28
7 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3
8 INT12082 Localization of IL6 365 0.81 241.78 105.78
9 INT4742 Gene_expression of Tac1 177 0.78 69.99 102.66
10 INT7344 Gene_expression of TAC1 132 0.75 35.48 68.26
11 INT19511 Localization of Il6 212 0.81 118.17 67.67
12 INT11937 Localization of Il6 228 0.81 139.83 64.39
13 INT9657 Positive_regulation of Gene_expression of Il6 237 0.70 180.45 63.6
14 INT10706 Regulation of Il6 150 0.62 93.23 62.34
15 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87
16 INT49993 Positive_regulation of Gene_expression of Il6 149 0.70 88.07 53.78
17 INT9234 Negative_regulation of Gene_expression of IL6 171 0.59 101.61 53.15
18 INT8690 Localization of Tac1 71 0.80 22.98 50.75
19 INT4985 Positive_regulation of Tac1 81 0.69 35.79 50.67
20 INT9210 Regulation of IL6 166 0.62 125.61 49.95
21 INT8713 Regulation of Tac1 56 0.60 25.29 45.94
22 INT4776 Localization of TAC1 82 0.78 16.89 45.21
23 INT14853 Negative_regulation of Tac1 80 0.59 30.87 45.06
24 INT50957 Negative_regulation of Il6 134 0.59 79.08 42.67
25 INT4850 Binding of Tac1 57 0.47 14.25 42.17
26 INT11939 Negative_regulation of Il6 138 0.59 87.46 41.24
27 INT9239 Regulation of Gene_expression of IL6 106 0.61 75.24 36.53
28 INT8837 Positive_regulation of TAC1 59 0.67 21.94 35.97
29 INT4727 Regulation of TAC1 60 0.47 6.74 32.83
30 INT9658 Negative_regulation of Gene_expression of Il6 110 0.59 66.29 32.58
31 INT9655 Regulation of Il6 98 0.62 70.92 31.95
32 INT22239 Negative_regulation of TAC1 52 0.57 12.96 31.41
33 INT56290 Negative_regulation of Gene_expression of Il6 79 0.59 47.98 31.07
34 INT50230 Positive_regulation of Localization of IL6 105 0.70 69.21 29.52
35 INT86437 Binding of IL6 154 0.48 121.22 29.3
36 INT116737 Localization of Mif 63 0.81 52.97 28.11
37 INT11773 Gene_expression of Tac1 56 0.77 10 25.72
38 INT8779 Binding of TAC1 50 0.47 11.19 25.57
39 INT51474 Binding of Il6 55 0.48 44.99 20.52
40 INT49985 Transcription of Il6 62 0.72 40.13 20.29
41 INT40750 Gene_expression of Mif 61 0.78 34.59 20.28
42 INT51054 Negative_regulation of Localization of IL6 45 0.59 24.48 18.97
43 INT11938 Positive_regulation of Localization of Il6 61 0.70 35.72 18.25
44 INT12360 Regulation of Tac1 31 0.61 5.9 18
45 INT61626 Transcription of IL6 73 0.72 42.04 17.86
46 INT9656 Regulation of Gene_expression of Il6 57 0.62 33.3 17.71
47 INT50932 Positive_regulation of Positive_regulation of Il6 36 0.69 24.9 16.12
48 INT116736 Positive_regulation of Mif 40 0.70 31.93 15.37
49 INT49532 Regulation of Gene_expression of Il6 43 0.61 25.8 14.99
50 INT49376 Negative_regulation of Localization of Il6 37 0.59 12.66 14.99
51 INT11980 Positive_regulation of Tac1 27 0.69 6.17 14.5
52 INT55256 Negative_regulation of Localization of Il6 38 0.58 16.12 13.67
53 INT54763 Binding of Il6 82 0.48 63.27 12.89
54 INT55255 Positive_regulation of Localization of Il6 48 0.69 24.88 12.76
55 INT12084 Regulation of Localization of IL6 36 0.61 20.32 12.34
56 INT72949 Binding of Mif 31 0.46 23.12 11.65
57 INT50933 Transcription of Il6 38 0.72 24.31 11.58
58 INT49396 Negative_regulation of Positive_regulation of Il6 29 0.59 16.39 11.31
59 INT4723 Transcription of Tac1 26 0.71 8.33 11.18
60 INT11936 Positive_regulation of Positive_regulation of Il6 34 0.50 26.85 10.59
61 INT48806 Negative_regulation of Binding of Tac1 11 0.56 0.83 10.52
62 INT11047 Positive_regulation of Positive_regulation of IL6 45 0.66 28.7 9.37
63 INT12358 Regulation of Gene_expression of Tac1 17 0.60 3.34 8.84
64 INT23331 Positive_regulation of Localization of Tac1 10 0.54 4.63 8.76
65 INT4984 Positive_regulation of Positive_regulation of Tac1 11 0.50 5.34 8.73
66 INT108202 Positive_regulation of PIK3CG 47 0.67 25.83 8.25
67 INT22700 Positive_regulation of Gene_expression of Tac1 13 0.69 6.89 8.2
68 INT32210 Gene_expression of Mif 13 0.75 28.48 7.79
69 INT87139 Negative_regulation of Positive_regulation of Il6 18 0.59 10.65 7.76
70 INT51206 Regulation of Gene_expression of Tac1 13 0.45 5.92 7.74
71 INT14548 Localization of Tac1 13 0.78 1.43 7.48
72 INT12359 Negative_regulation of Tac1 26 0.58 8.16 6.89
73 INT11975 Transcription of Tac1 24 0.71 4.06 6.72
74 INT15674 Positive_regulation of Gene_expression of Tac1 17 0.68 4.97 6.56
75 INT517 Regulation of Mif 16 0.62 5.43 6.55
76 INT516 Negative_regulation of Mif 13 0.59 6.69 6.08
77 INT64724 Positive_regulation of Transcription of IL6 26 0.69 13.63 5.96
78 INT129645 Negative_regulation of Gene_expression of TAC1 5 0.42 3.33 5.55
79 INT64716 Regulation of Positive_regulation of Il6 7 0.54 2.83 5.34
80 INT64723 Regulation of Positive_regulation of IL6 13 0.61 12.59 5.19
81 INT49375 Regulation of Localization of Il6 16 0.62 4.54 5.08
82 INT174339 Positive_regulation of Localization of Mif 7 0.61 8.27 4.95
83 INT14771 Regulation of Localization of Tac1 4 0.48 1.77 4.83
84 INT8838 Positive_regulation of Localization of TAC1 7 0.49 0.86 4.7
85 INT41816 Negative_regulation of Localization of Tac1 5 0.35 1.2 4.66
86 INT118274 Positive_regulation of Positive_regulation of PIK3CG 8 0.64 4.81 4.62
87 INT52133 Regulation of Localization of Il6 7 0.61 5.35 4.37
88 INT86919 Negative_regulation of PIK3CG 40 0.57 21.16 3.97
89 INT116738 Positive_regulation of Gene_expression of Mif 14 0.68 10.99 3.8
90 INT117561 Positive_regulation of Transcription of Tac1 6 0.69 3.19 3.78
91 INT91887 Negative_regulation of Pik3cg 12 0.41 5.01 3.67
92 INT53142 Negative_regulation of Gene_expression of Tac1 7 0.56 1.59 3.61
93 INT81695 Gene_expression of OSM 14 0.75 7.29 3.58
94 INT66924 Positive_regulation of Transcription of Il6 18 0.68 11.8 3.53
95 INT64725 Regulation of Transcription of IL6 9 0.45 7.96 3.49
96 INT81403 Positive_regulation of Regulation of Il6 4 0.44 1.81 3.37
97 INT64715 Phosphorylation of Il6 7 0.81 4.24 3.36
98 INT15276 Binding of Tac1 6 0.36 0.56 3.16
99 INT73017 Regulation of Gene_expression of TAC1 5 0.54 0.44 3.08
100 INT94947 Positive_regulation of Transcription of Il6 9 0.67 6.91 3.04
101 INT130226 Positive_regulation of Gene_expression of Mif 4 0.58 15.75 3.03
102 INT74674 Transcription of TAC1 7 0.67 1 3.01
103 INT105783 Protein_catabolism of IL6 7 0.48 4.72 2.95
104 INT51307 Negative_regulation of Positive_regulation of TAC1 4 0.42 2 2.82
105 INT203137 Binding of Mif 6 0.31 9.46 2.71
106 INT73837 Positive_regulation of Gene_expression of TAC1 6 0.67 3.49 2.68
107 INT172186 Gene_expression of IL6ST 20 0.75 11.63 2.67
108 INT64714 Positive_regulation of Phosphorylation of Il6 4 0.50 3.22 2.67
109 INT174687 Regulation of Positive_regulation of Il6 10 0.61 9.07 2.61
110 INT40748 Negative_regulation of Mif 6 0.56 8.33 2.46
111 INT148025 Localization of Pik3cg 1 0.58 0.69 2.34
112 INT10558 Regulation of Regulation of IL6 6 0.45 4.94 2.33
113 INT36927 Regulation of Transcription of Tac1 3 0.26 0.33 2.27
114 INT49139 Positive_regulation of Positive_regulation of Tac1 4 0.68 1.74 2.24
115 INT49183 Positive_regulation of Positive_regulation of TAC1 4 0.49 0.66 2.15
116 INT58469 Negative_regulation of Positive_regulation of IL6 16 0.42 8.1 2.14
117 INT100498 Negative_regulation of Positive_regulation of Tac1 3 0.41 2.81 2.06
118 INT52197 Negative_regulation of Transcription of Il6 8 0.43 3.8 2.05
119 INT103304 Positive_regulation of Mif 6 0.48 8.66 2.05
120 INT61650 Protein_catabolism of Tac1 3 0.52 0.88 1.98
121 INT64959 Positive_regulation of Negative_regulation of IL6 5 0.42 5.16 1.86
122 INT155455 Negative_regulation of Phosphorylation of Il6 1 0.31 2.5 1.76
123 INT164275 Gene_expression of Alox5ap 3 0.55 3.79 1.72
124 INT233649 Gene_expression of Npy5r 1 0.57 0.6 1.69
125 INT135275 Regulation of Negative_regulation of Il6 4 0.45 0.89 1.67
126 INT44149 Regulation of Gene_expression of Mif 6 0.54 2.45 1.63
127 INT353326 Negative_regulation of Localization of Mif 1 0.45 1.28 1.59
128 INT216932 Positive_regulation of Negative_regulation of Il6 3 0.38 4.88 1.55
129 INT122204 Positive_regulation of Alox5ap 1 0.26 0.23 1.53
130 INT133422 Binding of IL6ST 10 0.40 4.9 1.49
131 INT148026 Positive_regulation of Pik3cg 4 0.45 0.54 1.46
132 INT98448 Regulation of Binding of Il6 3 0.39 2.6 1.46
133 INT77368 Regulation of Regulation of Il6 3 0.35 1.86 1.45
134 INT98449 Positive_regulation of Binding of Il6 3 0.44 2.96 1.44
135 INT87062 Positive_regulation of Binding of IL6 10 0.49 11.8 1.42
136 INT80770 Positive_regulation of Binding of Tac1 2 0.12 0.45 1.37
137 INT253987 Regulation of Localization of Mif 3 0.43 1.65 1.27
138 INT41418 Regulation of Mif 2 0.40 3.86 1.24
139 INT82003 Negative_regulation of Localization of Tac1 2 0.20 0.1 1.23
140 INT75923 Positive_regulation of IL6ST 5 0.45 2.49 1.21
141 INT190075 Regulation of Transcription of Il6 2 0.45 2.17 1.18
142 INT121368 Transcription of Mif 5 0.72 2.71 1.15
143 INT50174 Negative_regulation of Gene_expression of Tac1 3 0.40 0.32 1.11
144 INT10559 Negative_regulation of Regulation of IL6 4 0.37 1.76 1.1
145 INT173589 Localization of OSM 4 0.58 1.65 1.07
146 INT82483 Negative_regulation of Positive_regulation of Tac1 3 0.47 0 1.06
147 INT102827 Protein_catabolism of Mif 1 0.33 0 1.06
148 INT155696 Gene_expression of PIK3CG 16 0.65 8.54 1.02
149 INT134260 Negative_regulation of Transcription of Il6 2 0.25 1.39 0.99
150 INT152021 Regulation of Negative_regulation of IL6 3 0.32 1.38 0.98
151 INT188232 Positive_regulation of OSM 7 0.41 1.57 0.94
152 INT162048 Regulation of OSM 4 0.43 3.3 0.94
153 INT24851 Negative_regulation of Regulation of TAC1 1 0.02 0 0.93
154 INT64958 Negative_regulation of Transcription of IL6 6 0.50 3.58 0.92
155 INT105370 Binding of Npy5r 2 0.00 0.33 0.9
156 INT60985 Regulation of Transcription of Tac1 4 0.27 1.75 0.88
157 INT115192 Phosphorylation of IL6 7 0.70 1.55 0.84
158 INT23842 Protein_catabolism of TAC1 2 0.96 0.57 0.84
159 INT192851 Phosphorylation of Il6 7 0.68 3.12 0.82
160 INT353328 Regulation of Positive_regulation of Mif 1 0.40 0.89 0.81
161 INT49181 Regulation of Positive_regulation of Tac1 1 0.12 0 0.81
162 INT113536 Positive_regulation of Phosphorylation of Tac1 1 0.07 0.08 0.79
163 INT84761 Positive_regulation of Binding of TAC1 1 0.32 0 0.78
164 INT113535 Phosphorylation of Tac1 1 0.12 0.08 0.78
165 INT300843 Regulation of Transcription of Il6 3 0.37 3.4 0.76
166 INT108204 Regulation of PIK3CG 9 0.12 4.16 0.75
167 INT52196 Negative_regulation of Regulation of Il6 3 0.42 3.42 0.74
168 INT2108 Localization of Mif 5 0.77 2.7 0.73
169 INT158354 Negative_regulation of Binding of Il6 2 0.20 2.21 0.71
170 INT80464 Regulation of Npy5r 1 0.08 0.79 0.71
171 INT32209 Regulation of Gene_expression of Mif 3 0.59 3.41 0.66
172 INT113538 Regulation of Binding of TAC1 2 0.44 0.15 0.66
173 INT130229 Regulation of Negative_regulation of Mif 1 0.39 1.36 0.66
174 INT353322 Negative_regulation of Positive_regulation of Mif 1 0.38 0.35 0.66
175 INT190187 Regulation of Gene_expression of PIK3CG 1 0.13 0 0.65
176 INT44148 Negative_regulation of Gene_expression of Mif 6 0.41 0.95 0.64
177 INT14433 Regulation of Binding of Tac1 1 0.13 0.27 0.64
178 INT261602 Positive_regulation of Binding of Il6 2 0.50 1.75 0.62
179 INT122470 Negative_regulation of Negative_regulation of TAC1 1 0.41 0 0.62
180 INT138730 Negative_regulation of Negative_regulation of Il6 3 0.09 1.04 0.61
181 INT323909 Positive_regulation of Gene_expression of OSM 2 0.29 0.67 0.61
182 INT41634 Positive_regulation of Negative_regulation of Tac1 1 0.45 0 0.61
183 INT264490 Regulation of Negative_regulation of Il6 2 0.23 1.18 0.6
184 INT164276 Localization of Alox5ap 1 0.61 1.1 0.6
185 INT120997 Regulation of Npy5r 1 0.00 0.54 0.6
186 INT243055 Gene_expression of Aoc3 1 0.20 1.54 0.57
187 INT188433 Negative_regulation of Binding of IL6 6 0.42 2.03 0.56
188 INT61025 Negative_regulation of Negative_regulation of Il6 3 0.43 1.15 0.56
189 INT31890 Positive_regulation of Protein_catabolism of Tac1 1 0.06 0 0.56
190 INT65954 Positive_regulation of Transcription of Tac1 2 0.43 0.78 0.55
191 INT132781 Phosphorylation of PIK3CG 8 0.52 4.83 0.53
192 INT80466 Gene_expression of Npy5r 2 0.39 0.82 0.52
193 INT113826 Positive_regulation of Negative_regulation of TAC1 1 0.01 0 0.51
194 INT337079 Negative_regulation of Gene_expression of Mif 1 0.41 4.17 0.51
195 INT55360 Positive_regulation of Npy5r 2 0.37 0 0.5
196 INT220268 Regulation of Regulation of Il6 2 0.12 0.89 0.49
197 INT14409 Positive_regulation of Negative_regulation of Tac1 1 0.27 0.31 0.49
198 INT31891 Protein_catabolism of Tac1 1 0.12 0 0.49
199 INT115189 Regulation of Phosphorylation of IL6 1 0.04 0 0.48
200 INT240020 Regulation of Binding of IL6 4 0.36 4.38 0.46
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