GO:0002678

From wiki-pain
Jump to: navigation, search
Name positive regulation of chronic inflammatory response
Categary Process
Go Slim No
Go Link GO:0002678
Unique Molecular Interactions 59
Total Molecular Interactions 68
Total Single Events 1100
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of chronic inflammatory response. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of chronic inflammatory response. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT291578 Negative_regulation of Pde12 Positive_regulation of Pde5a 1 0.03 1.11 1.67
2 INT291583 GUCY2C Regulation of Pde5a 1 0.00 1.12 1.45
3 INT257304 Pde5a Positive_regulation of Oprd1 1 0.15 0.48 0.89
4 INT221257 Pde5a Positive_regulation of PRKG1 3 0.07 0.19 0.86
5 INT291581 Pde5a Regulation of Localization of Abat 1 0.03 0 0.83
6 INT257222 Binding of Ltp and Pde5a 2 0.07 0.14 0.75
7 INT257302 Cnp Regulation of Protein_catabolism of Pde5a 1 0.05 0.49 0.7
8 INT291579 Pde12 Regulation of Binding of Pde5a 1 0.02 0.41 0.6
9 INT220051 Fcgr4 Positive_regulation of Gene_expression of Ido1 1 0.01 1.24 0.55
10 INT291580 Pde5a Regulation of Abat 1 0.04 0.39 0.48
11 INT104447 Ido1 Negative_regulation of Binding of Atp7b 1 0.00 0.68 0.43
12 INT257229 Binding of PRKG1 and Pde5a 1 0.01 0.17 0.41
13 INT220050 Ctla4 Positive_regulation of Ido1 1 0.31 1.45 0.38
14 INT221259 Pde5a Positive_regulation of Localization of PRKG1 1 0.00 0.06 0.37
15 INT275094 Pde5a Regulation of Ltp 1 0.05 0 0.35
16 INT316929 Pde5a Regulation of Ephb1 1 0.03 0.17 0.27
17 INT270046 Ido1 Positive_regulation of Positive_regulation of Hmox1 1 0.15 0.8 0.27
18 INT280181 Pde5a Positive_regulation of Regulation of Cpox 1 0.00 0.16 0.26
19 INT257224 Pde5a Positive_regulation of Phosphorylation of Creb1 1 0.03 0.09 0.2
20 INT220053 Il10 Positive_regulation of Ido1 1 0.14 0.74 0.19
21 INT202297 Pde5a Positive_regulation of Prkg1 1 0.00 0.13 0.18
22 INT263180 Binding of PDE5A and COPD 1 0.01 1 0.15
23 INT263175 PDE5A Regulation of COPD 1 0.00 1 0.15
24 INT323345 Ido1 Positive_regulation of Gene_expression of Tlr4 1 0.14 0.69 0.13
25 INT268083 Ido1 Negative_regulation of Tyrp1 1 0.22 0 0.13
26 INT268082 Ido1 Positive_regulation of Gpr35 1 0.04 0 0.13
27 INT257217 Binding of Pde2a and Pde5a 1 0.03 0 0.1
28 INT170330 Regulation of Regulation of Gene_expression of Ido1 1 0.01 0.38 0.08
29 INT226906 Binding of Ido1 and Il6 1 0.07 0.67 0.08
30 INT257221 Negative_regulation of Binding of Src and Pde5a 1 0.03 0 0.08
31 INT257219 Binding of Src and Pde5a 1 0.02 0 0.08
32 INT222489 Npr2 Positive_regulation of Pde5a 1 0.00 0.16 0.07
33 INT222429 Nps Positive_regulation of Pde5a 1 0.00 0.16 0.07
34 INT268088 Tdo2 Positive_regulation of Gene_expression of Ido1 1 0.41 0.09 0.04
35 INT337608 Pde5a Regulation of Cnga1 1 0.00 0 0.04
36 INT263197 Binding of PDE3A and Pde5a 1 0.03 0.18 0.04
37 INT170328 Gene_expression of Ido1 Positive_regulation of Hmga2 1 0.01 0.13 0.04
38 INT275090 Twist1 Positive_regulation of Gene_expression of Pde5a 1 0.02 0.62 0.04
39 INT275095 Twist1 Positive_regulation of Pde5a 1 0.03 0.62 0.04
40 INT170337 Gene_expression of Ido1 Positive_regulation of MRXS5 1 0.01 0.12 0.03
41 INT170326 Ido1 Positive_regulation of Cpox 1 0.07 0.12 0.03
42 INT263198 Pde5a Negative_regulation of PDE4A 1 0.09 0.16 0.03
43 INT170338 Gene_expression of Ido1 Positive_regulation of IGHD2-15 1 0.02 0.12 0.03
44 INT170327 Ido1 Positive_regulation of Gene_expression of Cpox 1 0.07 0.12 0.03
45 INT331897 Binding of PDE5A and Pde5a 1 0.02 0.64 0.03
46 INT222556 Pde5a Regulation of Localization of LH 1 0.00 0.06 0
47 INT313871 Pde5a Positive_regulation of Pah 1 0.49 0.97 0
48 INT209159 Binding of LHCGR and PDE5A 1 0.01 0 0
49 INT263181 Binding of Pde1a and Pde5a 1 0.03 0 0
50 INT275091 Negative_regulation of Twist1 Positive_regulation of Pde5a 1 0.02 0.06 0
51 INT98236 LOC360919 Positive_regulation of Pde5a 1 0.00 0.33 0
52 INT268021 Pde5a Positive_regulation of Kcnj5 1 0.01 0 0
53 INT263183 Binding of Pde1b and Pde5a 1 0.03 0 0
54 INT268052 Pde5a Positive_regulation of Positive_regulation of PRKG1 1 0.00 0 0
55 INT268022 Pde5a Positive_regulation of Gene_expression of Kcnj5 1 0.01 0 0
56 INT222471 Gnrh1 Positive_regulation of Pde5a 1 0.00 0.07 0
57 INT98235 Pde5a Negative_regulation of Pdpk1 1 0.00 0.32 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of chronic inflammatory response. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of chronic inflammatory response. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT76336 Negative_regulation of PDE5A 192 0.59 112.02 20.09
2 INT109110 Positive_regulation of Pde5a 29 0.63 11.16 16.65
3 INT209 Positive_regulation of Pde5a 30 0.21 2.54 16.31
4 INT170308 Gene_expression of Ido1 159 0.75 69.51 15.98
5 INT94861 Gene_expression of Pde5a 40 0.69 14.73 13.27
6 INT94859 Negative_regulation of Pde5a 67 0.43 33.66 10.28
7 INT95207 Negative_regulation of Pde5a 46 0.58 32.01 10.14
8 INT170295 Positive_regulation of Ido1 40 0.67 28.89 7.61
9 INT170315 Positive_regulation of Gene_expression of Ido1 50 0.67 25.39 6.06
10 INT94862 Positive_regulation of Gene_expression of Pde5a 10 0.20 4.23 5.18
11 INT11298 Gene_expression of Ido1 6 0.58 6.71 4.85
12 INT170311 Negative_regulation of Ido1 16 0.48 14.47 4.81
13 INT143557 Positive_regulation of Ido1 6 0.40 5.34 4.8
14 INT73128 Regulation of Pde5a 7 0.37 4.42 4.27
15 INT73127 Gene_expression of Pde5a 18 0.76 5.25 3.31
16 INT131472 Regulation of Pde5a 11 0.42 6.95 3.06
17 INT136675 Transcription of Pde5a 6 0.63 4.74 2.71
18 INT92877 Gene_expression of PDE5A 35 0.76 17.1 2.7
19 INT94860 Negative_regulation of Gene_expression of Pde5a 2 0.33 3.2 2.64
20 INT257298 Regulation of Positive_regulation of Pde5a 1 0.19 2.03 2.54
21 INT257299 Binding of Pde5a 14 0.27 4.31 2.45
22 INT170323 Regulation of Gene_expression of Ido1 11 0.60 8.74 2.33
23 INT257301 Protein_catabolism of Pde5a 5 0.30 1.97 2.26
24 INT108422 Binding of Pde5a 11 0.36 3.07 2.07
25 INT165648 Negative_regulation of Transcription of Pde5a 1 0.41 3.6 1.93
26 INT143561 Positive_regulation of Positive_regulation of Ido1 1 0.36 1.84 1.89
27 INT150248 Positive_regulation of Gene_expression of Ido1 2 0.43 2.68 1.77
28 INT291576 Positive_regulation of Protein_catabolism of Pde5a 1 0.12 1.15 1.43
29 INT73126 Positive_regulation of Gene_expression of Pde5a 3 0.59 0.55 1.31
30 INT242945 Localization of PDE5A 9 0.75 4.57 1.28
31 INT79598 Regulation of PDE5A 16 0.60 8.68 1.17
32 INT103043 Binding of PDE5A 16 0.37 7.79 1.12
33 INT220046 Positive_regulation of Negative_regulation of Ido1 1 0.41 2.98 1.12
34 INT88177 Negative_regulation of Ido1 3 0.25 0.51 1.02
35 INT257200 Phosphorylation of Pde5a 1 0.25 0 0.94
36 INT165644 Regulation of Transcription of Pde5a 1 0.44 1.65 0.91
37 INT164144 Phosphorylation of Pde5a 4 0.19 1.15 0.87
38 INT220043 Positive_regulation of Positive_regulation of Ido1 2 0.41 1.94 0.83
39 INT177532 Localization of Pde5a 2 0.56 0.96 0.81
40 INT143559 Positive_regulation of Protein_catabolism of Ido1 1 0.29 0.93 0.79
41 INT143560 Protein_catabolism of Ido1 1 0.52 0.93 0.79
42 INT143558 Negative_regulation of Negative_regulation of Ido1 1 0.25 0.49 0.76
43 INT165645 Positive_regulation of Negative_regulation of Pde5a 3 0.37 1.58 0.74
44 INT165647 Negative_regulation of Negative_regulation of Pde5a 1 0.31 1.22 0.67
45 INT257202 Protein_catabolism of Pde5a 2 0.38 0.36 0.66
46 INT165646 Positive_regulation of Transcription of Pde5a 1 0.33 1.21 0.66
47 INT208 Negative_regulation of Positive_regulation of Pde5a 3 0.17 2.02 0.65
48 INT275071 Negative_regulation of Protein_catabolism of Pde5a 1 0.17 0.36 0.6
49 INT242944 Negative_regulation of Localization of PDE5A 3 0.35 3.18 0.59
50 INT170299 Negative_regulation of Gene_expression of Ido1 12 0.57 2.59 0.5
51 INT257211 Negative_regulation of Localization of Pde5a 1 0.13 0.2 0.48
52 INT291577 Positive_regulation of Phosphorylation of Pde5a 1 0.12 0.35 0.48
53 INT220048 Protein_catabolism of Ido1 1 0.81 1.03 0.47
54 INT130371 Negative_regulation of Gene_expression of PDE5A 3 0.43 1.59 0.45
55 INT270034 Negative_regulation of Positive_regulation of Ido1 1 0.19 2.23 0.42
56 INT79597 Positive_regulation of Negative_regulation of PDE5A 5 0.50 3.39 0.41
57 INT130372 Transcription of PDE5A 7 0.72 1.93 0.4
58 INT79599 Protein_catabolism of PDE5A 7 1.00 3.16 0.39
59 INT270027 Regulation of Positive_regulation of Ido1 1 0.23 1.17 0.39
60 INT170318 Regulation of Ido1 6 0.38 2.63 0.38
61 INT275073 Positive_regulation of Negative_regulation of Pde5a 1 0.22 0.45 0.3
62 INT117995 Regulation of Negative_regulation of PDE5A 3 0.44 2.4 0.29
63 INT183429 Localization of Pde5a 5 0.56 1.61 0.25
64 INT303483 Positive_regulation of PDE5A 2 0.39 1.5 0.23
65 INT261276 Positive_regulation of Positive_regulation of Pde5a 1 0.26 0.07 0.21
66 INT42375 Positive_regulation of Positive_regulation of Pde5a 2 0.14 0.1 0.19
67 INT261275 Negative_regulation of Localization of Pde5a 2 0.31 1.11 0.18
68 INT42376 Regulation of Positive_regulation of Pde5a 1 0.03 0 0.18
69 INT213222 Negative_regulation of Protein_catabolism of PDE5A 1 0.24 0.65 0.16
70 INT11299 Binding of Ido1 1 0.31 0.15 0.15
71 INT177528 Negative_regulation of Binding of Pde5a 1 0.34 0.46 0.15
72 INT263121 Negative_regulation of Negative_regulation of PDE5A 2 0.43 1.33 0.14
73 INT242949 Phosphorylation of PDE5A 2 0.68 0.05 0.13
74 INT275069 Negative_regulation of Gene_expression of Pde5a 1 0.26 0.54 0.13
75 INT170320 Binding of Ido1 1 0.36 0.19 0.11
76 INT170297 Positive_regulation of Regulation of Ido1 1 0.39 0.29 0.1
77 INT303482 Positive_regulation of Protein_catabolism of PDE5A 1 0.20 1.27 0.1
78 INT261274 Negative_regulation of Protein_catabolism of Pde5a 1 0.20 0.18 0.09
79 INT339608 Localization of Ido1 1 0.14 0.41 0.08
80 INT257205 Transcription of Pde5a 1 0.21 0 0.08
81 INT213216 Positive_regulation of Gene_expression of PDE5A 2 0.37 2.08 0.04
82 INT183435 Regulation of Localization of Pde5a 1 0.34 0.35 0.04
83 INT323262 Negative_regulation of Negative_regulation of Pde5a 1 0.03 1.32 0.04
84 INT263185 Regulation of Gene_expression of Pde5a 1 0.12 0.19 0.03
85 INT269744 Negative_regulation of Binding of PDE5A 2 0.43 0.74 0
86 INT162907 Regulation of Gene_expression of PDE5A 2 0.51 0 0
87 INT269741 Positive_regulation of Localization of PDE5A 1 0.04 0.65 0
88 INT268038 Regulation of Negative_regulation of Pde5a 1 0.03 0 0
89 INT150246 Negative_regulation of Gene_expression of Ido1 1 0.07 0 0
90 INT170301 Negative_regulation of Negative_regulation of Ido1 1 0.36 0.32 0
91 INT170310 Transcription of Ido1 1 0.61 0.52 0
92 INT150247 Transcription of Ido1 1 0.10 0 0
93 INT150249 Negative_regulation of Transcription of Ido1 1 0.08 0 0
94 INT162922 Negative_regulation of Transcription of PDE5A 1 0.41 0 0
95 INT92876 Regulation of Protein_catabolism of PDE5A 1 0.45 0.71 0
96 INT162912 Regulation of Transcription of PDE5A 1 0.44 0 0
97 INT162915 Positive_regulation of Regulation of PDE5A 1 0.40 0 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox