GO:0002826

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Name negative regulation of T-helper 1 type immune response
Categary Process
Go Slim No
Go Link GO:0002826
Unique Molecular Interactions 70
Total Molecular Interactions 96
Total Single Events 572
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of T-helper 1 type immune response. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of T-helper 1 type immune response. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT325267 Il33 Positive_regulation of Gene_expression of Il4 1 0.16 1.59 0.69
2 INT325263 Il33 Positive_regulation of Gene_expression of Il5 1 0.16 1.59 0.69
3 INT325270 Il33 Positive_regulation of Gene_expression of Il6 1 0.20 1.59 0.69
4 INT54304 Il1rl1 Regulation of Regulation of Pdyn 1 0.04 0.23 0.54
5 INT164902 Binding of IL1RL1 and IL33 4 0.37 1.2 0.53
6 INT325259 Il33 Positive_regulation of Gene_expression of Spg21 1 0.07 1.23 0.53
7 INT325269 Il33 Positive_regulation of Spg21 1 0.05 1.11 0.48
8 INT164890 Binding of IL1RAP and IL33 1 0.09 0.2 0.36
9 INT164904 Binding of IL1A and IL33 1 0.39 0.19 0.35
10 INT300732 IL33 Positive_regulation of IL13 1 0.00 0 0.34
11 INT300728 IL33 Positive_regulation of IL4 1 0.00 0 0.33
12 INT325266 Positive_regulation of Spg21 Positive_regulation of Il33 1 0.05 0.75 0.32
13 INT325265 Il33 Positive_regulation of Gene_expression of Ik 1 0.01 0.67 0.32
14 INT226512 Il1rl1 Positive_regulation of Jun 1 0.12 0.34 0.29
15 INT226505 Il1rl1 Positive_regulation of Mapk8 1 0.04 0.4 0.29
16 INT226509 Il1rl1 Positive_regulation of Gene_expression of Mapk8 1 0.05 0.4 0.29
17 INT311046 Binding of CSF2 and IL33 1 0.00 1.86 0.26
18 INT272997 Binding of CYP3A4 and IL33 1 0.03 0 0.25
19 INT272998 IL33 Negative_regulation of CYP2D6 1 0.04 0 0.25
20 INT328621 Gene_expression of Il1rl1 Positive_regulation of Cfp 1 0.00 0.06 0.23
21 INT325276 Il33 Positive_regulation of Gene_expression of TNF 1 0.04 0.82 0.23
22 INT169567 IL33 Regulation of Pscs 1 0.03 0.46 0.19
23 INT164892 IL33 Regulation of Gene_expression of IL1RAP 1 0.06 0.2 0.18
24 INT63443 Binding of Pomc and Il1rl1 1 0.04 0.06 0.18
25 INT164908 Binding of IL1RAP and IL1RL1 1 0.08 0.1 0.18
26 INT319381 Binding of ST2 and IL33 1 0.13 1.01 0.18
27 INT355566 IL1RL1 Positive_regulation of Gene_expression of NOS2 1 0.00 0.27 0.17
28 INT302381 Il33 Regulation of Gene_expression of Il4 1 0.01 0.76 0.16
29 INT226527 Il1rl1 Positive_regulation of Gene_expression of IK 1 0.00 0.42 0.15
30 INT226507 Il1rl1 Positive_regulation of Gene_expression of Jun 1 0.13 0.2 0.15
31 INT226518 Il1rl1 Positive_regulation of MAPK14 1 0.04 0.2 0.15
32 INT305371 Binding of IL1RL1 and MRI1 1 0.09 0.95 0.15
33 INT304169 Il33 Positive_regulation of Gene_expression of Itgam 1 0.02 1.18 0.15
34 INT226520 Il1rl1 Positive_regulation of Gene_expression of MAPK14 1 0.03 0.2 0.15
35 INT226516 Il1rl1 Positive_regulation of Phosphorylation of Jun 1 0.02 0.19 0.14
36 INT169562 PDGFD Positive_regulation of Gene_expression of IL33 1 0.03 0.35 0.13
37 INT325272 Il1rl1 Positive_regulation of Gene_expression of TNF 1 0.02 0.41 0.12
38 INT325268 Il1rl1 Positive_regulation of Gene_expression of Spg21 1 0.05 0.41 0.12
39 INT25285 CBS Negative_regulation of Localization of IL1RL1 1 0.05 0 0.09
40 INT226515 Binding of Il1rl1 and Il33 1 0.02 0.36 0.08
41 INT303997 IL1RL1 Positive_regulation of Lep 1 0.01 0.2 0.07
42 INT325256 Chchd8 Regulation of Il1rl1 1 0.00 0.33 0.05
43 INT325255 Chchd8 Regulation of Il33 1 0.00 0.33 0.05
44 INT325261 Ralbp1 Positive_regulation of Gene_expression of Il33 1 0.01 0 0.05
45 INT164899 IL33 Positive_regulation of IFNG 1 0.25 0.05 0
46 INT285996 Binding of ACAT1 and IL1RL1 1 0.00 0 0
47 INT164907 IFNG Positive_regulation of Gene_expression of IL1RL1 1 0.31 0.11 0
48 INT204927 Binding of LGMN and IL33 1 0.00 0.52 0
49 INT164895 IL33 Positive_regulation of Gene_expression of CCL2 1 0.16 0.05 0
50 INT164901 IL33 Positive_regulation of Gene_expression of CXCL10 1 0.16 0.05 0
51 INT164906 IL33 Positive_regulation of Gene_expression of IL4 1 0.43 0.05 0
52 INT164910 IL33 Positive_regulation of Gene_expression of CXCL1 1 0.12 0.05 0
53 INT164900 STAT6 Positive_regulation of Gene_expression of IL1RL1 1 0.42 0.06 0
54 INT276606 Binding of DBT and IL33 1 0.01 0 0
55 INT164891 STAT1 Positive_regulation of Gene_expression of IL1RL1 1 0.41 0.06 0
56 INT164911 Binding of IL1RL1 and ITS 1 0.48 0 0
57 INT164897 IL4 Positive_regulation of Gene_expression of IL1RL1 1 0.54 0.06 0
58 INT325271 Positive_regulation of Il33 Regulation of Gene_expression of Il1rl1 1 0.22 0 0
59 INT164912 IL33 Positive_regulation of Gene_expression of IL8 1 0.45 0.05 0
60 INT164903 IL33 Positive_regulation of Gene_expression of CXCL2 1 0.12 0.05 0
61 INT164889 IL33 Positive_regulation of Gene_expression of IFNG 1 0.25 0.05 0
62 INT164909 IL33 Positive_regulation of Phosphorylation of NFKBIA 1 0.53 0.05 0
63 INT276608 Binding of UBE2S and IL33 1 0.00 0.32 0
64 INT164893 IL33 Positive_regulation of Gene_expression of IL6 1 0.46 0.05 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of T-helper 1 type immune response. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of T-helper 1 type immune response. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT11854 Gene_expression of Il1rl1 57 0.77 30.19 38.25
2 INT11855 Positive_regulation of Gene_expression of Il1rl1 19 0.69 12.22 14.57
3 INT65638 Negative_regulation of Gene_expression of Il1rl1 12 0.58 7.86 11.7
4 INT226402 Gene_expression of Il33 60 0.77 23.82 8.67
5 INT87432 Regulation of Gene_expression of Il1rl1 6 0.58 4.5 6.62
6 INT15299 Gene_expression of IL1RL1 37 0.69 10.09 3.43
7 INT164920 Gene_expression of IL33 22 0.76 13.63 3.16
8 INT45014 Regulation of IL1RL1 12 0.14 1.87 2.67
9 INT52601 Positive_regulation of Il1rl1 12 0.66 1.34 2.22
10 INT325254 Positive_regulation of Il33 19 0.69 6.56 2.09
11 INT25286 Localization of IL1RL1 7 0.56 3.17 2.07
12 INT325244 Localization of Il33 1 0.80 4.17 1.8
13 INT28681 Gene_expression of Il1rl1 4 0.55 3.04 1.46
14 INT28493 Positive_regulation of IL1RL1 10 0.47 3.44 1.11
15 INT7552 Negative_regulation of IL1RL1 12 0.42 1.68 0.87
16 INT63442 Localization of Il1rl1 2 0.12 0.05 0.87
17 INT325230 Positive_regulation of Gene_expression of Il33 1 0.50 1.47 0.83
18 INT112386 Positive_regulation of Gene_expression of IL1RL1 4 0.47 2.72 0.77
19 INT28682 Negative_regulation of Gene_expression of Il1rl1 2 0.42 0.31 0.75
20 INT204929 Binding of IL33 18 0.08 4.74 0.7
21 INT226421 Regulation of Il33 2 0.45 2.7 0.68
22 INT164916 Binding of IL1RL1 9 0.33 1.84 0.66
23 INT226403 Regulation of Gene_expression of Il33 2 0.61 1.94 0.63
24 INT273000 Localization of IL33 5 0.45 1.77 0.56
25 INT82749 Negative_regulation of Gene_expression of IL1RL1 4 0.40 2 0.52
26 INT273003 Positive_regulation of IL33 4 0.26 3.27 0.49
27 INT325251 Positive_regulation of Localization of Il33 1 0.69 1.03 0.45
28 INT325250 Regulation of Positive_regulation of Il33 2 0.45 1.16 0.39
29 INT273005 Negative_regulation of IL33 4 0.07 2.4 0.38
30 INT80742 Regulation of Il1rl1 1 0.08 0.09 0.37
31 INT325234 Negative_regulation of Il33 1 0.43 0.67 0.37
32 INT164919 Transcription of IL1RL1 2 0.64 2.74 0.35
33 INT325231 Negative_regulation of Negative_regulation of Il33 1 0.43 0.67 0.34
34 INT226389 Localization of Il1rl1 2 0.53 0.93 0.31
35 INT319433 Positive_regulation of Localization of IL1RL1 1 0.35 1.39 0.26
36 INT226397 Positive_regulation of Il1rl1 2 0.31 1.04 0.25
37 INT325238 Negative_regulation of Il1rl1 1 0.27 0.55 0.17
38 INT325246 Regulation of Localization of Il33 1 0.27 0.23 0.16
39 INT325252 Positive_regulation of Gene_expression of Il1rl1 1 0.36 0.43 0.15
40 INT319410 Positive_regulation of Transcription of IL1RL1 1 0.48 1.49 0.14
41 INT169566 Positive_regulation of Gene_expression of IL33 1 0.41 0.38 0.14
42 INT325249 Binding of Il33 1 0.37 0.72 0.13
43 INT319432 Positive_regulation of Localization of IL33 1 0.26 1.02 0.13
44 INT116052 Phosphorylation of Il1rl1 1 0.05 0.1 0.13
45 INT164918 Regulation of Gene_expression of IL33 2 0.44 1.09 0.12
46 INT169564 Negative_regulation of Gene_expression of IL33 1 0.38 0.3 0.11
47 INT25287 Negative_regulation of Localization of IL1RL1 1 0.04 0 0.09
48 INT72901 Negative_regulation of Il1rl1 2 0.27 0.59 0.06
49 INT211317 Positive_regulation of Positive_regulation of IL1RL1 1 0.25 0.09 0.04
50 INT325253 Negative_regulation of Positive_regulation of Il33 1 0.42 0 0.03
51 INT325247 Negative_regulation of Gene_expression of Il33 1 0.42 0 0.03
52 INT325237 Transcription of Il33 1 0.68 0.15 0
53 INT325243 Regulation of Gene_expression of Il1rl1 1 0.44 0 0
54 INT276617 Negative_regulation of Localization of IL33 1 0.03 0.28 0
55 INT286002 Negative_regulation of Binding of IL1RL1 1 0.02 0 0
56 INT193363 Regulation of Binding of IL1RL1 1 0.02 0 0
57 INT325235 Transcription of Il1rl1 1 0.49 0.15 0
58 INT325245 Positive_regulation of Localization of Il1rl1 1 0.31 0 0
59 INT164914 Regulation of Gene_expression of IL1RL1 1 0.40 0.09 0
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