GO:0002863

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Name positive regulation of inflammatory response to antigenic stimulus
Categary Process
Go Slim No
Go Link GO:0002863
Unique Molecular Interactions 77
Total Molecular Interactions 138
Total Single Events 445
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of inflammatory response to antigenic stimulus. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of inflammatory response to antigenic stimulus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT194647 Binding of CD28 and CD80 15 0.40 4.9 3.22
2 INT186126 Binding of CD28 and CTLA4 9 0.52 4.13 3.12
3 INT299783 Binding of Cd28 and Cd80 7 0.14 6.49 2.49
4 INT194646 Binding of CD28 and CD86 7 0.40 2.69 2.21
5 INT239037 Binding of Cd28 and Cd86 9 0.16 3.69 2.14
6 INT239038 Negative_regulation of Binding of Cd28 and Cd86 3 0.17 1.5 1.05
7 INT103928 Binding of Cd28 and Trav6-3 3 0.03 0.55 0.98
8 INT265210 Binding of Ctla4 and Cd28 2 0.16 1.45 0.93
9 INT174509 Binding of CD4 and CD28 1 0.26 1.68 0.84
10 INT188567 IRF6 Positive_regulation of Gene_expression of CD28 1 0.05 1.28 0.82
11 INT103937 Cps1 Negative_regulation of Gene_expression of Cd28 1 0.03 0.19 0.51
12 INT299785 CTLA4 Negative_regulation of Binding of CD28 2 0.17 1.8 0.5
13 INT149121 Binding of CD80 and Cd28 2 0.04 0.95 0.46
14 INT188565 IRF6 Regulation of Gene_expression of CD28 1 0.03 0.7 0.43
15 INT188572 CD14 Regulation of Gene_expression of CD28 1 0.11 0.6 0.4
16 INT287819 Binding of CD80 and Cd28 1 0.25 0.7 0.4
17 INT324802 Binding of Cd24a and Siglecg 1 0.03 1.34 0.4
18 INT287818 Negative_regulation of Binding of CD80 and Cd28 1 0.29 0.7 0.4
19 INT222212 TFAM Negative_regulation of Cd28 1 0.02 1.17 0.39
20 INT353020 Binding of CD80 and Positive_regulation of Gene_expression of CD28 1 0.13 0.35 0.34
21 INT299780 Binding of Cd28 and Cd80 1 0.21 1.36 0.34
22 INT299791 Negative_regulation of Binding of CD28 and CTLA4 1 0.18 0.77 0.32
23 INT186127 CTLA4 Negative_regulation of CD28 1 0.19 0.74 0.32
24 INT289954 Binding of APC and CD28 1 0.03 0.38 0.28
25 INT289959 Negative_regulation of Binding of CD28 and CD80 1 0.07 0.24 0.23
26 INT238006 Cxcl10 Positive_regulation of Gene_expression of Cd28 1 0.24 0.91 0.21
27 INT324824 Positive_regulation of Binding of Cd24a and Siglecg 1 0.03 0.68 0.2
28 INT64964 Binding of Alb and Cd24 1 0.02 0.2 0.2
29 INT288006 Binding of CD28 and LRRC23 1 0.02 0.54 0.19
30 INT188568 Negative_regulation of IRF6 Positive_regulation of CD28 1 0.05 0.19 0.19
31 INT171127 Binding of CD28 and IFN1@ 1 0.39 0.36 0.19
32 INT188571 IRF6 Positive_regulation of CD28 1 0.06 0.19 0.19
33 INT324822 Binding of Cd24a and Hsp90aa1 1 0.10 0.71 0.19
34 INT324797 Binding of Cd24a and Hmgb1 1 0.19 0.66 0.19
35 INT318298 MECOM Negative_regulation of Binding of CD28 1 0.00 1.08 0.18
36 INT300753 Binding of Cd28 and Positive_regulation of Transcription of IL13 1 0.00 0 0.17
37 INT194700 CD28 Positive_regulation of MAPK1 1 0.10 0.55 0.16
38 INT265215 Cd28 Regulation of Transcription of thd 1 0.00 0 0.15
39 INT194817 CD28 Positive_regulation of Il4 1 0.15 0.41 0.13
40 INT194717 CD28 Positive_regulation of IL13 1 0.03 0.41 0.13
41 INT188356 Binding of Cd28 and Positive_regulation of Localization of Cd4 1 0.30 0.18 0.11
42 INT299782 Cd28 Regulation of Gene_expression of Il2 1 0.01 0.43 0.11
43 INT188360 Binding of Cd28 and Positive_regulation of Localization of Cd8a 1 0.09 0.18 0.11
44 INT64966 Binding of AGFG1 and Cd24 1 0.00 0.1 0.1
45 INT265212 Cd28 Negative_regulation of Gene_expression of Il17a 1 0.10 0 0.09
46 INT351031 Binding of CD28 and CD96 1 0.02 0.36 0.09
47 INT194674 CD28 Negative_regulation of Gene_expression of IL13 1 0.02 0.06 0.08
48 INT270201 Binding of CD28 and Cd86 1 0.10 0.58 0.08
49 INT270203 Binding of CD28 and Apc 1 0.04 0.58 0.08
50 INT265222 Binding of Cd28 and Gopc 1 0.04 0 0.08
51 INT270202 Binding of CD28 and Cd80 1 0.09 0.58 0.08
52 INT265221 Binding of Cd28 and Positive_regulation of Gene_expression of Il17a 1 0.15 0.09 0.08
53 INT174561 Binding of Cd28 and Ncl 1 0.00 0.62 0.07
54 INT252353 Regulation of Binding of LCP2 and Cd28 1 0.37 0 0.06
55 INT252355 Binding of LCP2 and Cd28 1 0.30 0 0.06
56 INT252338 Binding of Cd28 and Lat 1 0.30 0 0.06
57 INT237192 Cd28 Positive_regulation of LPT 1 0.01 0.15 0.06
58 INT194831 CD28 Positive_regulation of Gene_expression of Il4 1 0.15 0 0.06
59 INT252335 Regulation of Binding of Cd28 and Lat 1 0.37 0 0.06
60 INT265224 Cd28 Positive_regulation of Gene_expression of IFN1@ 1 0.34 0.25 0.05
61 INT265218 Cd28 Positive_regulation of Gene_expression of Gopc 1 0.06 0.25 0.05
62 INT265225 Cd28 Positive_regulation of IFN1@ 1 0.47 0.25 0.05
63 INT299762 Binding of Cd28 and Positive_regulation of Gene_expression of Il2 1 0.03 0.07 0.04
64 INT288007 Binding of CD28 and CD40 1 0.05 0.51 0.03
65 INT211191 CD28 Positive_regulation of Gene_expression of IL2 1 0.15 0.15 0.03
66 INT252354 TNF Negative_regulation of Cd28 1 0.05 0.48 0
67 INT289301 Binding of CD59 and Cd24a 1 0.02 1.06 0
68 INT273716 Binding of Cd28 and Icam1 1 0.09 0 0
69 INT277811 Binding of CD28 and DCPS 1 0.04 0.05 0
70 INT273720 Binding of Cd28 and Itgb2 1 0.10 0 0
71 INT265223 Negative_regulation of Binding of Ctla4 and Cd28 1 0.18 0.14 0
72 INT265216 Cd28 Positive_regulation of Gene_expression of Il17a 1 0.10 0 0
73 INT149120 Binding of CTLA4 and Cd28 1 0.03 0.14 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of inflammatory response to antigenic stimulus. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of inflammatory response to antigenic stimulus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT171134 Gene_expression of CD28 67 0.65 32.55 13.61
2 INT73504 Binding of CD28 35 0.45 15.99 10.04
3 INT94125 Gene_expression of Cd28 38 0.67 21.73 7.75
4 INT116902 Positive_regulation of CD28 17 0.47 13.56 4.27
5 INT188355 Binding of Cd28 25 0.34 8.29 3.38
6 INT111482 Gene_expression of Cd24a 23 0.72 13.74 3.37
7 INT174527 Negative_regulation of CD28 13 0.35 5.06 2.65
8 INT144652 Negative_regulation of Binding of CD28 6 0.55 3.09 2.28
9 INT174511 Positive_regulation of Gene_expression of CD28 7 0.41 4.31 1.83
10 INT171133 Localization of CD28 8 0.71 3.42 1.48
11 INT94126 Positive_regulation of Cd28 9 0.50 4.23 1.33
12 INT174557 Negative_regulation of Gene_expression of Cd28 7 0.43 4.42 1.2
13 INT174550 Negative_regulation of Cd28 7 0.33 4.7 1.06
14 INT138543 Negative_regulation of Cd28 3 0.11 2.1 1.01
15 INT147634 Regulation of Cd28 2 0.44 3.23 0.82
16 INT340843 Binding of Cd24a 1 0.02 0.24 0.8
17 INT149698 Negative_regulation of Binding of Cd28 2 0.15 1.21 0.75
18 INT149697 Binding of Cd28 2 0.12 1.16 0.74
19 INT279357 Regulation of Binding of CD28 1 0.18 0.3 0.72
20 INT188586 Negative_regulation of Gene_expression of CD28 6 0.34 1.9 0.69
21 INT265207 Positive_regulation of Gene_expression of Cd28 3 0.43 1.47 0.66
22 INT329718 Transcription of Cd28 1 0.09 1.54 0.63
23 INT93728 Gene_expression of Cd28 8 0.35 7.11 0.59
24 INT174556 Regulation of Gene_expression of Cd28 3 0.42 2.9 0.57
25 INT340842 Regulation of Gene_expression of Cd24a 1 0.42 0.08 0.53
26 INT64961 Binding of Cd24 4 0.15 0.64 0.5
27 INT326696 Regulation of Cd24a 2 0.44 0 0.48
28 INT270195 Positive_regulation of Positive_regulation of CD28 1 0.25 2.49 0.41
29 INT287809 Negative_regulation of Positive_regulation of Cd28 1 0.26 0.65 0.38
30 INT174476 Regulation of CD28 3 0.34 0.67 0.37
31 INT329720 Negative_regulation of Transcription of Cd28 1 0.08 0.9 0.35
32 INT188577 Transcription of CD28 1 0.43 0.54 0.32
33 INT188583 Regulation of Transcription of CD28 1 0.22 0.54 0.32
34 INT171131 Protein_catabolism of CD28 1 0.73 0.47 0.27
35 INT278163 Negative_regulation of Localization of CD28 1 0.08 0.87 0.26
36 INT252317 Negative_regulation of Binding of Cd28 3 0.31 1.09 0.21
37 INT220835 Localization of Cd28 1 0.65 0.45 0.2
38 INT220837 Regulation of Cd28 2 0.41 0.14 0.19
39 INT220838 Protein_catabolism of Cd28 1 0.60 0.46 0.16
40 INT135526 Positive_regulation of Gene_expression of Cd28 2 0.32 0.9 0.15
41 INT329712 Positive_regulation of Cd28 2 0.10 1 0.13
42 INT254742 Gene_expression of Cd24 1 0.11 0.46 0.09
43 INT254732 Localization of Cd24 1 0.12 0.46 0.09
44 INT355318 Positive_regulation of Gene_expression of Cd24a 1 0.47 1.17 0.09
45 INT254740 Negative_regulation of Cd24 1 0.07 0.08 0.07
46 INT326709 Negative_regulation of Gene_expression of Cd24a 3 0.40 0.86 0
47 INT200854 Transcription of Cd24a 2 0.66 0.4 0
48 INT170944 Localization of Cd28 1 0.31 0.53 0
49 INT355323 Negative_regulation of Cd24a 1 0.40 0.08 0
50 INT264194 Positive_regulation of Binding of CD28 1 0.23 0.22 0
51 INT270194 Regulation of Gene_expression of CD28 1 0.22 1.1 0
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