GO:0002866

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Name positive regulation of acute inflammatory response to antigenic stimulus
Categary Process
Go Slim No
Go Link GO:0002866
Unique Molecular Interactions 115
Total Molecular Interactions 156
Total Single Events 2028
Pain Genes Associated 3

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of acute inflammatory response to antigenic stimulus. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of acute inflammatory response to antigenic stimulus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT143270 Binding of Cnr1 and Gprasp1 4 0.54 0.64 4.18
2 INT127128 Binding of CNR1 and CNR2 8 0.39 3.98 3.97
3 INT264929 Binding of Cnr1 and Gnaz 1 0.18 1.71 2.89
4 INT104219 SCD Positive_regulation of Cnr1 1 0.00 2.67 2.54
5 INT143271 Binding of Gprasp1 and Positive_regulation of Negative_regulation of Cnr1 1 0.78 0.16 2.53
6 INT143272 Binding of CNR1 and Gprasp1 1 0.01 0.17 2.42
7 INT238914 Positive_regulation of CNR1 Positive_regulation of Phosphorylation of MAPK1 1 0.19 3.22 2.35
8 INT198958 Cnr1 Positive_regulation of Kcnj9 1 0.00 0.15 2.24
9 INT264928 Binding of Cnr1 and Hrh1 1 0.01 1.61 1.92
10 INT264922 Binding of Cnr1 and Mors1 1 0.14 0.1 1.71
11 INT192081 Igkv11-125 Positive_regulation of Cnr1 1 0.10 0.23 1.51
12 INT150069 Cnr1 Regulation of Cnr2 2 0.50 0.83 1.42
13 INT355252 Binding of Cacna1a and Cnr1 1 0.04 0 1.31
14 INT198957 Binding of Cnr1 and Mastl 1 0.00 0 1.31
15 INT192080 Foxm1 Positive_regulation of Cnr1 2 0.14 0.72 1.3
16 INT169289 CNR1 Positive_regulation of EGFR 1 0.62 0.36 1.28
17 INT210982 Binding of Cnr1 and Cfp 2 0.22 1.27 1.2
18 INT63384 Binding of Cnr1 and Insrr 1 0.03 0.24 1.2
19 INT238916 CNR1 Positive_regulation of Phosphorylation of MAPK1 1 0.19 1.61 1.17
20 INT212815 WAS Positive_regulation of CNR1 1 0.01 0.62 1.16
21 INT212824 WAS Positive_regulation of Cnr1 1 0.21 0.62 1.16
22 INT264930 Gnaz Positive_regulation of Negative_regulation of Cnr1 1 0.20 0 1.14
23 INT225104 CNR1 Positive_regulation of Gene_expression of RETNLB 1 0.01 1.41 1.14
24 INT110671 Binding of Cnr1 and Alox5 1 0.07 0.2 1.13
25 INT123454 CNR1 Regulation of Fos 1 0.00 0.06 1.12
26 INT123455 CNR1 Regulation of Positive_regulation of Fos 1 0.00 0.06 1.12
27 INT351443 Cnr1 Regulation of Positive_regulation of Vta1 1 0.12 0.93 0.99
28 INT264932 D2Mit212 Positive_regulation of Binding of Cnr1 1 0.06 0.2 0.94
29 INT120380 Cnr1 Positive_regulation of Gene_expression of Fos 1 0.31 0.45 0.93
30 INT111078 Binding of Cnr1 and Cnr2 2 0.05 0 0.92
31 INT264925 D2Mit212 Negative_regulation of Cnr1 1 0.05 0 0.84
32 INT72418 Binding of Cnr1 and Cnr2 3 0.42 0.07 0.79
33 INT111361 Cnr1 Negative_regulation of Localization of Calca 1 0.01 0 0.78
34 INT226122 Ghrl Regulation of Cnr1 1 0.25 0.09 0.76
35 INT292598 CNR1 Regulation of ABAT 1 0.08 0.32 0.75
36 INT166414 Gprasp1 Regulation of Negative_regulation of Cnr1 1 0.37 0.3 0.75
37 INT81011 CNR1 Positive_regulation of Gene_expression of PENK 1 0.54 0 0.75
38 INT292599 CNR1 Regulation of Localization of ABAT 1 0.08 0.32 0.75
39 INT127584 Binding of CNR1 and Ctbp1 1 0.00 0.6 0.75
40 INT144455 Binding of CNR1 and GPM6A 1 0.02 0 0.74
41 INT102123 Ngf Regulation of Gene_expression of Cnr1 1 0.53 0.42 0.71
42 INT102121 Gdnf Regulation of Gene_expression of Cnr1 1 0.45 0.42 0.71
43 INT150067 Cnr1 Regulation of Gene_expression of Oprd1 1 0.01 0.23 0.69
44 INT307046 Tmie Positive_regulation of Cnr1 1 0.05 0.31 0.69
45 INT120381 Binding of CNR1 and Fos 1 0.00 0.52 0.68
46 INT210983 Calb1 Positive_regulation of Cnr1 1 0.01 0.81 0.68
47 INT264927 Cnr1 Regulation of Gnaz 1 0.23 0.05 0.66
48 INT213895 Mastl Regulation of Gene_expression of Cnr1 1 0.17 0.26 0.66
49 INT128978 Cnr1 Positive_regulation of Cnr2 1 0.56 0.96 0.65
50 INT110342 Binding of CNR1 and TRPV1 1 0.33 0 0.63
51 INT111839 Binding of Cnr1 and Cnr2 1 0.05 0.53 0.6
52 INT169299 CNR1 Positive_regulation of Localization of IL8 1 0.20 0.11 0.59
53 INT169291 CNR1 Positive_regulation of Gene_expression of PTPLA 1 0.19 0.11 0.59
54 INT169292 Positive_regulation of CNR1 Positive_regulation of Gene_expression of PTPLA 1 0.19 0.11 0.59
55 INT169290 CNR1 Positive_regulation of Negative_regulation of TXK 1 0.10 0.18 0.58
56 INT169286 CNR1 Positive_regulation of Phosphorylation of EGFR 1 0.45 0.18 0.57
57 INT203033 Cnr1 Regulation of Cnr2 1 0.15 0.29 0.56
58 INT311179 CNR1 Negative_regulation of Transcription of CNR2 1 0.41 2.05 0.55
59 INT141072 GPRASP1 Positive_regulation of Negative_regulation of CNR1 1 0.56 0.09 0.54
60 INT155359 CNR2 Negative_regulation of CNR1 1 0.46 0.5 0.54
61 INT156517 Binding of CNR1 and FAAH 3 0.38 1.53 0.53
62 INT111840 Binding of Cnr1 and sar 1 0.04 0.45 0.52
63 INT313376 Cnr1 Positive_regulation of Phosphorylation of Mapk14 1 0.20 0.38 0.5
64 INT313371 Cnr1 Positive_regulation of Gene_expression of Gfap 1 0.35 0.39 0.5
65 INT77377 Binding of Cnr1 and Fbln5 1 0.02 0 0.48
66 INT268473 Negative_regulation of CNR1 Negative_regulation of Cysltr1 1 0.00 1.02 0.48
67 INT141729 NR3C1 Regulation of Positive_regulation of Cnr1 1 0.06 0.7 0.47
68 INT168110 Binding of Cnr1 and Dbh 1 0.04 0.64 0.47
69 INT101325 Binding of Cnr1 and Trpv1 1 0.32 0 0.47
70 INT168111 Dbh Positive_regulation of Cnr1 1 0.05 0.64 0.47
71 INT101327 Binding of Cnr1 and Amt 1 0.25 0 0.47
72 INT307048 Cnr1 Positive_regulation of Casp3 1 0.08 0 0.47
73 INT123714 Binding of Cnr1 and oh 1 0.01 0.3 0.47
74 INT226125 Ghrl Positive_regulation of Cnr1 1 0.44 0.06 0.46
75 INT139488 Oprm1 Positive_regulation of Cnr1 1 0.17 0.1 0.42
76 INT97789 Positive_regulation of Cnr1 Negative_regulation of Gene_expression of Nos2 1 0.12 0.23 0.4
77 INT156519 Binding of CNR1 and NAPEPLD 1 0.39 0.19 0.4
78 INT96833 Binding of WAS and Positive_regulation of Cnr1 1 0.02 0.69 0.39
79 INT313380 Binding of Cnr1 and Trpv1 1 0.36 0.09 0.39
80 INT95999 Binding of Npr1 and Cnr1 1 0.05 0 0.39
81 INT96836 WAS Positive_regulation of Cnr1 1 0.02 0.69 0.39
82 INT144795 Binding of Cnr1 and Gm4113 1 0.00 0.22 0.38
83 INT261499 CBS Positive_regulation of CNR1 1 0.01 0.48 0.35
84 INT226120 Cnr1 Positive_regulation of Prkag1 1 0.09 0 0.35
85 INT167047 TRPA1 Regulation of CNR1 1 0.12 0.1 0.35
86 INT142999 ATF7IP Negative_regulation of Binding of Cnr1 1 0.00 0.14 0.34
87 INT258574 Cysltr1 Positive_regulation of Positive_regulation of Cnr1 1 0.01 0.07 0.32
88 INT96000 Binding of Cnr1 and Slc3a1 1 0.14 0 0.31
89 INT313374 Cnr1 Regulation of Gene_expression of Cnr2 1 0.36 0 0.3
90 INT150200 Regulation of Binding of Cnr1 and Cnr2 1 0.01 0 0.3
91 INT166951 Binding of CNR1 and LYRM4 1 0.02 0.7 0.3
92 INT110670 Binding of Cnr1 and Trpv1 1 0.36 0.05 0.28
93 INT72419 Positive_regulation of Binding of Cnr1 and Cnr2 1 0.55 0 0.25
94 INT101326 Negative_regulation of Binding of Cnr1 and Amt 1 0.29 0 0.25
95 INT101324 Negative_regulation of Binding of Cnr1 and Trpv1 1 0.36 0 0.25
96 INT293505 Binding of Cnr1 and Slc17a7 1 0.11 0 0.23
97 INT249760 Positive_regulation of Cnr1 Negative_regulation of Gene_expression of Adipoq 1 0.20 0.81 0.22
98 INT249759 Positive_regulation of Cnr1 Positive_regulation of Lpl 1 0.29 0.74 0.21
99 INT118547 Msr1 Negative_regulation of CNR1 1 0.00 0 0.2
100 INT352355 Binding of CNR1 and EGFR 1 0.19 0.76 0.2
101 INT226123 Cnr1 Regulation of Prkag1 1 0.05 0.09 0.18
102 INT352354 EGFR Regulation of Gene_expression of CNR1 1 0.23 1.16 0.17
103 INT226130 Binding of Cnr1 and Prkag1 1 0.06 0 0.13
104 INT328063 IL4 Positive_regulation of Gene_expression of CNR1 1 0.14 0.93 0.11
105 INT325076 Negative_regulation of Ssr1 Negative_regulation of CNR1 1 0.05 0 0.11
106 INT328062 IL4 Regulation of CNR1 1 0.18 2.53 0.1
107 INT93124 Binding of CNR1 and Olfr907 1 0.00 0 0.09
108 INT308969 Binding of Cnr1 and Gpr18 1 0.11 0 0.08
109 INT86448 Binding of Cnr1 and Lipg 1 0.28 0.64 0.06
110 INT293221 Cd3e Regulation of Gene_expression of CNR1 1 0.03 0.06 0.06
111 INT319764 Large Positive_regulation of Transcription of Cnr1 1 0.19 0.21 0.05
112 INT352356 Gene_expression of CNR1 Positive_regulation of Gene_expression of EGFR 1 0.24 0.95 0.04
113 INT328061 IL4 Regulation of Gene_expression of CNR1 1 0.18 0.81 0
114 INT309889 Positive_regulation of CNR1 Positive_regulation of LPL 1 0.05 1.25 0
115 INT309887 Positive_regulation of CNR1 Positive_regulation of Localization of INS 1 0.05 1.04 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of acute inflammatory response to antigenic stimulus. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of acute inflammatory response to antigenic stimulus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT65731 Gene_expression of Cnr1 234 0.78 63.82 109.34
2 INT69764 Positive_regulation of Cnr1 126 0.70 67.8 91.49
3 INT74376 Gene_expression of Cnr1 173 0.78 73.43 89.7
4 INT65733 Positive_regulation of Cnr1 125 0.70 40.27 67.33
5 INT6894 Gene_expression of CNR1 168 0.78 74.07 62.84
6 INT50334 Negative_regulation of Cnr1 84 0.58 30.86 51.75
7 INT62630 Positive_regulation of CNR1 86 0.70 40.34 51.51
8 INT63383 Binding of Cnr1 77 0.48 22.28 44.61
9 INT16194 Binding of CNR1 82 0.48 20.75 39.59
10 INT12608 Regulation of CNR1 62 0.60 24.36 36.02
11 INT66005 Regulation of Cnr1 47 0.61 19.21 34.52
12 INT50308 Binding of Cnr1 61 0.48 14.41 33.52
13 INT111359 Localization of Cnr1 55 0.81 11.25 27.41
14 INT75418 Negative_regulation of Cnr1 41 0.59 14.65 27.28
15 INT74377 Regulation of Cnr1 38 0.59 16.93 24.77
16 INT10442 Negative_regulation of CNR1 47 0.59 20.88 20.2
17 INT79955 Localization of Cnr1 26 0.81 8.44 19.06
18 INT87932 Positive_regulation of Gene_expression of Cnr1 28 0.69 8.86 16.38
19 INT62629 Localization of CNR1 35 0.76 11.86 16.3
20 INT74375 Positive_regulation of Gene_expression of Cnr1 24 0.70 14.25 13.66
21 INT69763 Positive_regulation of Positive_regulation of Cnr1 12 0.50 9.05 12.46
22 INT106565 Negative_regulation of Gene_expression of Cnr1 19 0.59 6.98 9.93
23 INT10444 Positive_regulation of Gene_expression of CNR1 18 0.69 8.69 7.84
24 INT87976 Regulation of Gene_expression of Cnr1 9 0.58 6.87 7.51
25 INT86898 Negative_regulation of Gene_expression of Cnr1 13 0.55 3.33 7.25
26 INT96969 Positive_regulation of Positive_regulation of CNR1 9 0.48 1.27 7.19
27 INT10445 Transcription of CNR1 16 0.68 6.75 6.4
28 INT85404 Transcription of Cnr1 12 0.72 3.15 5.73
29 INT90961 Negative_regulation of Positive_regulation of Cnr1 7 0.42 0.6 5.24
30 INT90962 Regulation of Positive_regulation of Cnr1 6 0.61 1.25 4.99
31 INT111358 Regulation of Localization of Cnr1 3 0.39 0.09 4.53
32 INT74373 Phosphorylation of Cnr1 3 0.79 1.88 4.45
33 INT90983 Regulation of Gene_expression of Cnr1 8 0.45 2.59 4.03
34 INT87974 Transcription of Cnr1 15 0.65 2.51 4.02
35 INT113204 Negative_regulation of Positive_regulation of Cnr1 6 0.40 4.89 4.02
36 INT95556 Negative_regulation of Binding of Cnr1 5 0.58 3.1 3.67
37 INT84005 Negative_regulation of Positive_regulation of CNR1 7 0.41 3.55 3.66
38 INT80923 Negative_regulation of Binding of CNR1 7 0.19 0.78 3.61
39 INT10443 Regulation of Gene_expression of CNR1 10 0.50 3.96 3.06
40 INT106283 Regulation of Positive_regulation of Cnr1 3 0.37 2.61 3.05
41 INT111422 Positive_regulation of Regulation of CNR1 3 0.03 0.56 2.76
42 INT143189 Positive_regulation of Binding of Cnr1 3 0.35 0.37 2.74
43 INT90982 Regulation of Transcription of Cnr1 3 0.26 1.37 2.7
44 INT74556 Negative_regulation of Binding of Cnr1 4 0.59 1.13 2.67
45 INT166411 Positive_regulation of Negative_regulation of Cnr1 4 0.50 0.84 2.62
46 INT97807 Negative_regulation of Regulation of CNR1 2 0.09 0.89 2.51
47 INT125345 Positive_regulation of Localization of Cnr1 6 0.50 1.47 2.44
48 INT166412 Protein_catabolism of Cnr1 4 0.99 0.9 2.37
49 INT169300 Phosphorylation of CNR1 4 0.57 2.15 2.31
50 INT161098 Regulation of Positive_regulation of CNR1 3 0.45 2.22 1.87
51 INT87973 Regulation of Binding of Cnr1 7 0.58 0.33 1.86
52 INT264897 Negative_regulation of Negative_regulation of Cnr1 2 0.37 0.14 1.61
53 INT210002 Positive_regulation of Positive_regulation of Cnr1 3 0.47 1 1.54
54 INT123232 Protein_catabolism of CNR1 2 0.58 0.72 1.45
55 INT351302 Regulation of Regulation of Cnr1 1 0.10 0.78 1.39
56 INT213894 Positive_regulation of Transcription of Cnr1 3 0.69 0.81 1.34
57 INT59908 Negative_regulation of Gene_expression of CNR1 7 0.39 1.36 1.24
58 INT264905 Positive_regulation of Binding of Cnr1 1 0.50 0.12 1.19
59 INT135761 Positive_regulation of Localization of Cnr1 1 0.45 1.25 1.1
60 INT101336 Positive_regulation of Regulation of Cnr1 1 0.40 0 0.96
61 INT127440 Positive_regulation of Negative_regulation of Cnr1 2 0.50 1.57 0.94
62 INT123233 Negative_regulation of Protein_catabolism of CNR1 1 0.06 0.64 0.92
63 INT132868 Negative_regulation of Negative_regulation of CNR1 1 0.23 0 0.68
64 INT313381 Negative_regulation of Phosphorylation of CNR1 1 0.00 0.59 0.66
65 INT131513 Regulation of Regulation of Cnr1 1 0.25 0.64 0.6
66 INT132867 Negative_regulation of Transcription of CNR1 3 0.41 2.23 0.55
67 INT87975 Positive_regulation of Transcription of Cnr1 1 0.47 0 0.55
68 INT311190 Positive_regulation of Transcription of CNR1 1 0.48 2.02 0.55
69 INT85726 Negative_regulation of Localization of CNR1 1 0.01 0 0.55
70 INT141073 Positive_regulation of Protein_catabolism of CNR1 1 0.41 0.08 0.53
71 INT169307 Positive_regulation of Localization of CNR1 2 0.42 1.16 0.45
72 INT304860 Negative_regulation of Localization of Cnr1 1 0.25 0.09 0.44
73 INT128286 Regulation of Negative_regulation of CNR1 1 0.45 0.41 0.35
74 INT109493 Negative_regulation of Negative_regulation of Cnr1 1 0.32 0 0.35
75 INT130583 Regulation of Binding of Cnr1 2 0.41 0.17 0.26
76 INT328070 Regulation of Transcription of CNR1 1 0.18 0.57 0.1
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