GO:0003009

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Name skeletal muscle contraction
Categary Process
Go Slim No
Go Link GO:0003009
Unique Molecular Interactions 953
Total Molecular Interactions 1338
Total Single Events 13557
Pain Genes Associated 15

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for skeletal muscle contraction. They are ordered first by their pain relevance and then by number of times they were reported for skeletal muscle contraction. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT182124 Binding of IRF6 and TLR4 14 0.10 16.11 4.65
2 INT139706 Tnf Positive_regulation of Ltp 1 0.03 2.61 4.63
3 INT61359 TNF Positive_regulation of NFKB1 11 0.63 6.66 3.89
4 INT152501 Binding of Tnf and Tnfrsf1a 4 0.31 3 2.58
5 INT151826 Tnf Positive_regulation of TNF 1 0.04 3.38 2.51
6 INT117532 SETBP1 Positive_regulation of Gene_expression of TNF 1 0.54 0.85 2.44
7 INT122163 Binding of TNF and TNFRSF1B 6 0.44 6.06 2.41
8 INT139705 Negative_regulation of Tnf Positive_regulation of Ltp 1 0.03 1.19 2.3
9 INT279361 Binding of TNF and KLF1 4 0.00 3.72 2.19
10 INT94491 Il1b Positive_regulation of Gene_expression of Tnf 1 0.25 3.81 2.19
11 INT94504 Il6 Positive_regulation of Gene_expression of Tnf 1 0.30 3.8 2.19
12 INT86179 TNF Positive_regulation of Localization of IL6 5 0.35 1.66 2.17
13 INT148704 Binding of TNF and TNFRSF1A 5 0.44 3.3 2.09
14 INT196586 Negative_regulation of Mapk14 Negative_regulation of TNF 2 0.04 2.02 2.08
15 INT264953 Binding of POMC and TLR4 1 0.03 0.89 1.96
16 INT157767 Binding of TLR4 and LY96 8 0.54 4.05 1.95
17 INT217042 IRF6 Positive_regulation of TNF 4 0.27 3.03 1.95
18 INT279359 Binding of ADA and TNF 1 0.20 2.61 1.91
19 INT199287 TNF Positive_regulation of Transcription of Oprm1 2 0.02 1.86 1.8
20 INT224432 TNF Positive_regulation of Gene_expression of VEGFA 1 0.13 5.83 1.8
21 INT137207 Tnf Positive_regulation of Nfkb1 3 0.23 2.69 1.71
22 INT89379 TNF Positive_regulation of Gene_expression of IL6 5 0.50 4.37 1.69
23 INT79778 Tlr4 Positive_regulation of Localization of TNF 4 0.08 4.21 1.61
24 INT167202 TNF Regulation of Gene_expression of Ngf 1 0.10 1.47 1.6
25 INT209853 TNF Regulation of Gene_expression of CD36 1 0.61 3.41 1.59
26 INT266767 SFTPA1 Positive_regulation of Gene_expression of TNF 1 0.01 1.69 1.59
27 INT198653 TNF Positive_regulation of MIF 1 0.15 3.81 1.55
28 INT252633 Binding of TNF and Tnfrsf1b 4 0.05 3.66 1.54
29 INT167201 Gtf3a Regulation of TNF 1 0.01 1.39 1.52
30 INT158775 Regulation of Tnf Regulation of Ephb1 1 0.18 0.09 1.52
31 INT158777 Tnf Regulation of Ephb1 1 0.18 0.09 1.51
32 INT285569 TNF Negative_regulation of Gene_expression of Il6 1 0.03 2.83 1.46
33 INT72755 Tap1 Negative_regulation of TNF 1 0.43 2.45 1.46
34 INT131156 Binding of RUNX1 and TNF 2 0.03 3.44 1.42
35 INT160588 TNF Positive_regulation of Gene_expression of OPRM1 1 0.20 0.54 1.35
36 INT56087 TNF Regulation of Gene_expression of SERPINE1 1 0.43 1.67 1.33
37 INT294775 IRF6 Positive_regulation of TLR4 6 0.08 2.04 1.32
38 INT186393 Binding of TNF and Tnfrsf1a 9 0.37 8.55 1.29
39 INT70037 TNF Regulation of IL10 2 0.09 2.11 1.26
40 INT296796 Tbrs1 Positive_regulation of Gene_expression of TNF 1 0.00 1.58 1.26
41 INT151648 TLR4 Regulation of Gene_expression of ICAM1 1 0.00 2.86 1.24
42 INT197092 TNF Regulation of VEGFA 4 0.21 2.78 1.22
43 INT70035 TNF Regulation of Negative_regulation of PRF1 1 0.05 1.42 1.21
44 INT70032 TNF Regulation of PRF1 1 0.05 1.42 1.21
45 INT70040 TNF Regulation of Negative_regulation of IL10 1 0.09 1.42 1.21
46 INT328743 TNF Positive_regulation of Mapk14 1 0.04 1.4 1.21
47 INT194619 Il15 Positive_regulation of Gene_expression of TNF 1 0.24 2.23 1.2
48 INT133046 TNF Positive_regulation of Positive_regulation of NFKB1 5 0.54 3.23 1.19
49 INT113242 TNF Regulation of Transcription of OPRM1 2 0.45 1.53 1.19
50 INT314196 Ngf Positive_regulation of Tnf 1 0.50 1.98 1.18
51 INT231769 TNF Negative_regulation of Gene_expression of HMOX1 1 0.26 4.75 1.15
52 INT72754 Adamts7 Negative_regulation of TNF 1 0.28 1.64 1.13
53 INT89938 Tlr4 Positive_regulation of Gene_expression of TNF 6 0.25 1.3 1.12
54 INT107264 Binding of TNF and NCR3 1 0.30 1.42 1.1
55 INT139704 Tnf Positive_regulation of Mapk14 1 0.22 0.73 1.1
56 INT107266 Binding of HLA-DRB1 and TNF 1 0.29 1.41 1.1
57 INT267597 IL10 Negative_regulation of Gene_expression of TNF 1 0.03 2.24 1.1
58 INT107267 Binding of HLA-A and TNF 1 0.34 1.41 1.1
59 INT94495 Tnf Positive_regulation of Gene_expression of Il6 1 0.30 1.9 1.09
60 INT94500 Tnf Positive_regulation of Gene_expression of Il1b 1 0.25 1.9 1.09
61 INT139703 Tnf Positive_regulation of Mapk8 1 0.32 0.73 1.08
62 INT152502 Tnf Negative_regulation of Binding of Tnfrsf1a 1 0.37 0.6 1.08
63 INT119108 Binding of LTBR and TNF 2 0.15 1.47 1.07
64 INT114364 Hmgb1 Positive_regulation of Gene_expression of TNF 2 0.05 1.85 1.06
65 INT120312 Ghrh Regulation of Tnf 1 0.26 0.95 1.05
66 INT120314 Ghrh Regulation of Positive_regulation of Tnf 1 0.43 0.95 1.05
67 INT152504 Binding of CR1 and Tnf 1 0.00 0.49 1.04
68 INT133650 Epo Negative_regulation of TNF 1 0.35 2.7 1.04
69 INT182125 Binding of CD14 and TLR4 7 0.25 3.78 1.03
70 INT156245 NFKB1 Positive_regulation of Regulation of TNF 1 0.45 0.76 1.03
71 INT81545 Tnf Positive_regulation of Gtf3a 2 0.03 1.41 1.02
72 INT308804 Pld1 Positive_regulation of TNF 1 0.05 2.42 0.99
73 INT274895 Positive_regulation of Cbr2 Negative_regulation of Gene_expression of TNF 1 0.06 1.21 0.99
74 INT182022 TNF Positive_regulation of Gene_expression of Tnfrsf11b 1 0.06 1.56 0.98
75 INT209852 TNF Negative_regulation of Gene_expression of CD36 1 0.43 0.61 0.98
76 INT154255 Tnf Positive_regulation of IL1B 1 0.54 0.94 0.97
77 INT154254 Tnf Positive_regulation of Il6 1 0.36 0.94 0.97
78 INT114320 TNF Positive_regulation of Gene_expression of Il6 1 0.07 1.73 0.97
79 INT103133 TNF Positive_regulation of Gene_expression of IL8 2 0.48 1.26 0.96
80 INT133652 Epo Negative_regulation of Gene_expression of TNF 1 0.35 2.64 0.96
81 INT171264 TNF Positive_regulation of MMP1 2 0.10 2.05 0.95
82 INT188805 TNF Positive_regulation of Gene_expression of Crp 1 0.15 2.96 0.95
83 INT100018 TNF Positive_regulation of MAPK1 3 0.24 1.56 0.94
84 INT133050 TNF Positive_regulation of Gene_expression of ICAM1 3 0.67 1.91 0.94
85 INT182024 TNF Positive_regulation of Gene_expression of Il6 1 0.05 1.58 0.94
86 INT219154 Binding of HMGB1 and TLR4 2 0.17 4.45 0.93
87 INT336017 Vip Regulation of Tlr4 1 0.22 1.23 0.93
88 INT155259 RUNX1 Negative_regulation of Tnf 1 0.00 1.48 0.93
89 INT254242 TNF Positive_regulation of Gene_expression of DKK1 1 0.14 1.24 0.91
90 INT343909 IgG Positive_regulation of Gene_expression of TLR4 1 0.04 3.49 0.91
91 INT256646 Tnf Positive_regulation of Positive_regulation of Nfkb1 1 0.22 1.83 0.9
92 INT222988 TNF Positive_regulation of Protein_catabolism of COL1A1 1 0.01 1.66 0.9
93 INT211128 Binding of P4HB and TNF 1 0.09 0.97 0.9
94 INT211129 Negative_regulation of Binding of P4HB and TNF 1 0.10 0.97 0.9
95 INT80132 Binding of HLA-B and TNF 1 0.04 1.15 0.89
96 INT168281 Tlr4 Positive_regulation of Phosphorylation of Mapk4 1 0.06 1.05 0.89
97 INT142278 Slc8a1 Regulation of Tnf 1 0.14 0.07 0.89
98 INT116556 Olr1627 Negative_regulation of Regulation of Tnf 1 0.01 1.52 0.87
99 INT97795 IRF6 Positive_regulation of Localization of TNF 3 0.09 1.57 0.86
100 INT152868 Tnf Regulation of Gene_expression of Trpv1 1 0.27 0.25 0.86
101 INT110315 Negative_regulation of ALOX5 Negative_regulation of Gene_expression of TNF 1 0.47 0.74 0.85
102 INT215598 Positive_regulation of P2rx7 Positive_regulation of Localization of TNF 1 0.22 1.44 0.85
103 INT196638 TNF Positive_regulation of F2RL1 2 0.09 1.52 0.84
104 INT146919 Tnf Positive_regulation of Gene_expression of Ccl2 1 0.16 1.44 0.84
105 INT238641 Binding of TNF and Ifx 1 0.07 0.86 0.84
106 INT238642 Binding of TNF and Ada 1 0.03 0.86 0.84
107 INT105435 TNF Positive_regulation of IL6 5 0.25 4.45 0.83
108 INT162071 Gene_expression of MC1R Negative_regulation of Gene_expression of TNF 1 0.41 0.34 0.82
109 INT66206 Negative_regulation of TNF Positive_regulation of NFKB1 2 0.53 1.71 0.81
110 INT147755 Binding of GNRH1 and TNF 1 0.32 2.37 0.79
111 INT110518 Tnf Positive_regulation of Prkce 1 0.26 1.43 0.78
112 INT188531 Binding of TNF and PDXK 1 0.03 1.99 0.78
113 INT102163 Binding of TNF and Mmp9 1 0.12 0.88 0.78
114 INT306259 HDAC9 Negative_regulation of Gene_expression of TNF 1 0.21 0.89 0.78
115 INT102161 Binding of TNF and Mmp2 1 0.10 0.88 0.78
116 INT306258 HDAC4 Negative_regulation of Gene_expression of TNF 1 0.09 0.89 0.78
117 INT130138 TNF Negative_regulation of Gene_expression of S100A10 1 0.06 1.32 0.78
118 INT102162 Binding of TNF and Adam17 1 0.14 0.88 0.78
119 INT296797 Tlr9 Regulation of Positive_regulation of TNF 1 0.03 1.37 0.77
120 INT296798 Gopc Regulation of Positive_regulation of TNF 1 0.01 1.37 0.77
121 INT152869 Tnf Positive_regulation of Gene_expression of Trpv1 1 0.46 0.48 0.77
122 INT209883 TNF Positive_regulation of Gene_expression of TNFRSF11A 1 0.20 1.83 0.77
123 INT194644 Tlr4 Positive_regulation of TNF 6 0.58 2.42 0.76
124 INT149192 TNF Positive_regulation of Gene_expression of VCAM1 3 0.57 1.4 0.76
125 INT152949 Homer1 Regulation of Sgk1 1 0.28 0.18 0.76
126 INT152946 Homer1 Regulation of Cap1 1 0.32 0.18 0.76
127 INT26497 TNF Positive_regulation of Gene_expression of MMP2 1 0.44 1.5 0.75
128 INT152948 Homer1 Regulation of Gpr88 1 0.36 0.18 0.75
129 INT113472 TNF Positive_regulation of Localization of MMP14 1 0.47 0.45 0.75
130 INT308176 TNF Regulation of Tnfrsf1a 1 0.05 1.19 0.75
131 INT301141 Nsa2 Positive_regulation of TNF 1 0.01 0.6 0.74
132 INT301142 Negative_regulation of Nsa2 Positive_regulation of TNF 1 0.01 0.6 0.74
133 INT4875 TNF Regulation of MME 1 0.51 0.71 0.74
134 INT86657 TNF Regulation of H2-Ab1 1 0.02 0.84 0.74
135 INT190174 TNF Positive_regulation of MMP12 1 0.27 0.08 0.74
136 INT96301 Olr1742 Negative_regulation of Gene_expression of Tnf 1 0.14 0 0.74
137 INT211127 Regulation of Binding of MTX1 and TNF 1 0.22 0.71 0.74
138 INT211130 Binding of MTX1 and TNF 1 0.18 0.7 0.73
139 INT172147 Binding of IL15 and TNF 2 0.05 1.19 0.72
140 INT150992 Sfpq Negative_regulation of Gene_expression of Tnf 1 0.03 0.69 0.72
141 INT51006 PDYN Positive_regulation of TNF 1 0.11 0.84 0.72
142 INT117535 SND1 Positive_regulation of Gene_expression of TNF 1 0.06 0.29 0.71
143 INT113499 TNF Positive_regulation of Gene_expression of BHLHE23 1 0.25 0.1 0.71
144 INT159963 Tnf Positive_regulation of Localization of Il6 1 0.12 2.32 0.71
145 INT187115 Binding of TIMP1 and TNF 2 0.30 1.07 0.7
146 INT171901 Binding of TNF and Il1 2 0.18 1.07 0.7
147 INT117534 TNF Positive_regulation of Positive_regulation of SND1 1 0.06 0.29 0.7
148 INT117533 TNF Positive_regulation of Positive_regulation of SETBP1 1 0.34 0.29 0.7
149 INT83628 TNF Positive_regulation of Gene_expression of Cd59 1 0.06 1.09 0.7
150 INT172143 IL4 Positive_regulation of Protein_catabolism of TNF 2 0.11 1.7 0.69
151 INT172146 IL10 Positive_regulation of Protein_catabolism of TNF 2 0.15 1.69 0.69
152 INT83625 Tnf Positive_regulation of Gene_expression of Cd59 1 0.15 1.08 0.69
153 INT334395 IL1B Positive_regulation of Tnf 1 0.11 2.83 0.69
154 INT113959 TNF Positive_regulation of Gene_expression of IK 1 0.02 0.66 0.69
155 INT190527 TNF Positive_regulation of Gene_expression of Ros1 1 0.01 1.02 0.68
156 INT119107 Negative_regulation of Binding of LTBR and TNF 1 0.17 1.16 0.68
157 INT203758 Binding of IL6 and TNF 3 0.26 2.03 0.67
158 INT231349 Il10 Negative_regulation of Gene_expression of TNF 2 0.23 1.82 0.67
159 INT119105 Binding of FCGR1A and TNF 1 0.03 1.16 0.67
160 INT119106 Negative_regulation of Binding of FCGR1A and TNF 1 0.03 1.16 0.67
161 INT264338 Binding of IL-17 and Positive_regulation of Localization of TNF 1 0.04 1.71 0.67
162 INT314199 Mapk14 Regulation of Tnf 1 0.26 0.71 0.67
163 INT148139 Phosphorylation of Mapk14 Positive_regulation of Positive_regulation of Tnf 1 0.46 0.98 0.66
164 INT137142 Binding of ITIH4 and Positive_regulation of Localization of TNF 1 0.40 0.71 0.66
165 INT148138 Mapk14 Positive_regulation of Positive_regulation of Tnf 1 0.64 0.98 0.66
166 INT252293 Binding of TNF and Positive_regulation of Gene_expression of Ccl20 1 0.04 0.54 0.66
167 INT343851 Positive_regulation of Binding of IRF6 and TLR4 1 0.07 1.96 0.66
168 INT254230 Ik Negative_regulation of Gene_expression of TNF 1 0.00 1.29 0.65
169 INT295705 Binding of IK and TNF 1 0.00 0.27 0.64
170 INT292893 TNF Regulation of IL8 2 0.27 1.3 0.63
171 INT165047 Mapk14 Positive_regulation of Gene_expression of Tnf 1 0.73 0.8 0.63
172 INT176476 TNF Positive_regulation of Gene_expression of SELE 1 0.04 0.57 0.63
173 INT220117 Il6 Positive_regulation of TNF 1 0.01 2.45 0.63
174 INT165048 Trib3 Positive_regulation of Gene_expression of Tnf 1 0.08 0.8 0.63
175 INT148137 Tnf Positive_regulation of Positive_regulation of Mapk14 1 0.46 1 0.63
176 INT100030 TNF Positive_regulation of Mapk8 1 0.12 1.57 0.63
177 INT120851 NFKB1 Positive_regulation of Localization of TNF 3 0.04 2.05 0.62
178 INT60328 Il1b Positive_regulation of Tnf 2 0.29 1.84 0.62
179 INT9163 Tnf Regulation of Gene_expression of Glul 1 0.12 1.99 0.62
180 INT230595 Binding of TNF and Tecr 1 0.03 1 0.62
181 INT172048 Binding of TNF and MICA 1 0.29 1.63 0.62
182 INT61826 Tnf Negative_regulation of Il1b 1 0.39 0.89 0.62
183 INT66207 Positive_regulation of TNF Positive_regulation of NFKB1 1 0.42 0.08 0.61
184 INT339393 Tlr4 Positive_regulation of Nfkb1 1 0.24 2.06 0.61
185 INT293704 Binding of TNF and DDX41 1 0.00 1.01 0.61
186 INT114319 TNF Positive_regulation of Gene_expression of Il6r 1 0.05 0.91 0.61
187 INT308175 Negative_regulation of Mapk14 Negative_regulation of Localization of TNF 1 0.03 0.89 0.61
188 INT314197 Mapk14 Positive_regulation of Positive_regulation of Tnf 1 0.48 1.16 0.61
189 INT327334 Il10 Negative_regulation of TNF 1 0.02 1.46 0.6
190 INT179203 NLRP1 Regulation of Gene_expression of TNF 1 0.31 1.73 0.6
191 INT327164 RETNLB Regulation of TNF 1 0.00 2.27 0.6
192 INT96241 Il13 Negative_regulation of Tnf 1 0.08 0.6 0.59
193 INT263454 Negative_regulation of IRF6 Positive_regulation of TNF 1 0.12 0.49 0.59
194 INT56451 Ifng Positive_regulation of Tnf 1 0.00 1.92 0.59
195 INT61827 Tnf Regulation of Lta 1 0.40 1.5 0.58
196 INT176470 TNF Positive_regulation of Gene_expression of CCL2 1 0.15 0.62 0.58
197 INT176471 TNF Positive_regulation of Gene_expression of IL1B 1 0.02 0.61 0.57
198 INT94506 Tnf Positive_regulation of Gene_expression of Avp 1 0.31 0.98 0.57
199 INT162790 Binding of TLR4 and NOD2 1 0.36 0.51 0.57
200 INT236783 IRF6 Negative_regulation of Gene_expression of TLR4 1 0.01 1.17 0.57

Single Events

The table below shows the top 100 pain related interactions that have been reported for skeletal muscle contraction. They are ordered first by their pain relevance and then by number of times they were reported in skeletal muscle contraction. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82
2 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98
3 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81
4 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68
5 INT6852 Localization of TNF 883 0.81 705.95 270.84
6 INT6481 Binding of TNF 624 0.48 510.2 214.82
7 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210
8 INT13353 Positive_regulation of Tnf 332 0.70 248.75 148.1
9 INT9660 Regulation of TNF 363 0.62 312.94 139.99
10 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61
11 INT10166 Localization of Tnf 237 0.81 153.95 88.64
12 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99
13 INT58400 Negative_regulation of Tnf 182 0.59 129.97 71
14 INT49995 Positive_regulation of Gene_expression of Tnf 187 0.70 125.07 70.54
15 INT52800 Negative_regulation of Gene_expression of Tnf 142 0.59 92.27 55.47
16 INT117223 Gene_expression of TLR4 348 0.78 206.18 54.42
17 INT7898 Gene_expression of Homer1 123 0.78 31.52 53.67
18 INT22112 Positive_regulation of Localization of TNF 164 0.70 115.66 52.18
19 INT5307 Regulation of Tnf 87 0.62 78.71 43.4
20 INT13354 Transcription of TNF 108 0.72 85.81 42.32
21 INT53577 Negative_regulation of Localization of TNF 110 0.59 59.28 35.23
22 INT118734 Gene_expression of Tlr4 70 0.78 55.7 28.19
23 INT52801 Regulation of Gene_expression of Tnf 55 0.62 48.74 26.59
24 INT7899 Positive_regulation of Gene_expression of Homer1 41 0.70 7.29 25.98
25 INT47818 Positive_regulation of Homer1 48 0.70 11.11 24.05
26 INT134651 Binding of TLR4 89 0.48 66.96 23.19
27 INT66753 Negative_regulation of Positive_regulation of Tnf 45 0.59 35.28 22.33
28 INT8483 Positive_regulation of Positive_regulation of TNF 73 0.67 60.35 22.03
29 INT66751 Negative_regulation of Localization of Tnf 48 0.59 26 19.36
30 INT66755 Transcription of Tnf 45 0.72 37.1 19.11
31 INT117220 Positive_regulation of TLR4 64 0.69 53.61 17.33
32 INT10169 Positive_regulation of Localization of Tnf 44 0.70 27.71 16.75
33 INT19929 Negative_regulation of Positive_regulation of TNF 52 0.59 38.16 16.51
34 INT12087 Regulation of Localization of TNF 44 0.62 28.71 15.17
35 INT151120 Negative_regulation of Tlr4 18 0.59 21.09 14.46
36 INT10173 Binding of Tnf 45 0.48 35.6 14.32
37 INT64048 Positive_regulation of Positive_regulation of Tnf 32 0.70 21.24 13.74
38 INT6478 Negative_regulation of Binding of TNF 36 0.58 30.42 13.31
39 INT117222 Positive_regulation of Gene_expression of TLR4 80 0.70 51.6 12.9
40 INT89404 Regulation of Negative_regulation of TNF 30 0.45 24.47 12.71
41 INT118742 Positive_regulation of Tlr4 32 0.69 27.55 11.09
42 INT51265 Phosphorylation of TNF 32 0.81 25.33 10.75
43 INT80110 Regulation of Positive_regulation of TNF 34 0.44 25.79 9.78
44 INT57424 Positive_regulation of TNNT1 42 0.67 31.84 9.7
45 INT60995 Negative_regulation of Positive_regulation of Homer1 9 0.38 1.63 9.63
46 INT15242 Regulation of Gene_expression of Homer1 14 0.62 4.33 9.28
47 INT48860 Regulation of Localization of Tnf 25 0.61 20.68 8.78
48 INT146991 Positive_regulation of Gene_expression of Tlr4 21 0.69 20.76 8.69
49 INT86411 Negative_regulation of Negative_regulation of TNF 24 0.42 17.6 7.89
50 INT49490 Positive_regulation of Transcription of TNF 19 0.70 14.76 7.58
51 INT66752 Positive_regulation of Transcription of Tnf 15 0.68 10.86 7.26
52 INT295467 Negative_regulation of Gene_expression of Tlr4 11 0.58 7.94 6.83
53 INT69985 Positive_regulation of Negative_regulation of TNF 21 0.50 13.26 6.31
54 INT172084 Positive_regulation of Binding of TNF 21 0.50 15.31 6.06
55 INT97797 Localization of TLR4 18 0.77 13.78 6
56 INT67060 Negative_regulation of Transcription of TNF 17 0.59 12.94 5.88
57 INT143158 Negative_regulation of Gene_expression of TLR4 31 0.56 20.62 5.69
58 INT168279 Regulation of Tlr4 17 0.54 8.97 5.5
59 INT145767 Negative_regulation of TLR4 18 0.43 11.03 5.25
60 INT53974 Regulation of Homer1 14 0.39 4.71 4.9
61 INT55698 Regulation of Binding of TNF 13 0.44 8.98 4.74
62 INT68189 Gene_expression of TNNT1 27 0.75 14.87 4.03
63 INT66754 Negative_regulation of Transcription of Tnf 11 0.43 8.43 3.93
64 INT117075 Negative_regulation of Ikbkb 3 0.26 9.51 3.91
65 INT23088 Phosphorylation of Tnf 15 0.79 9.85 3.82
66 INT172173 Protein_catabolism of TNF 16 0.96 9.95 3.79
67 INT9798 Negative_regulation of Gene_expression of Homer1 10 0.41 2.04 3.77
68 INT186808 Transcription of TLR4 22 0.69 12.77 3.73
69 INT143159 Regulation of Gene_expression of TLR4 28 0.62 15.08 3.54
70 INT60714 Regulation of Positive_regulation of Homer1 3 0.04 0.64 3.46
71 INT122997 Phosphorylation of Rps6kb1 46 0.72 9.92 3.43
72 INT85985 Localization of TNNT1 10 0.78 6.66 3.26
73 INT65427 Regulation of Positive_regulation of Tnf 7 0.60 3.49 3.22
74 INT228677 Negative_regulation of Phosphorylation of Rps6kb1 24 0.51 3.88 2.97
75 INT145768 Regulation of TLR4 19 0.45 8.31 2.96
76 INT76191 Regulation of TNNT1 9 0.60 5.4 2.9
77 INT95049 Negative_regulation of Regulation of Tnf 4 0.42 1.64 2.84
78 INT58173 Negative_regulation of Homer1 5 0.43 1 2.79
79 INT82278 Positive_regulation of Positive_regulation of Homer1 5 0.13 2.32 2.73
80 INT98607 Regulation of Regulation of TNF 8 0.44 6.95 2.56
81 INT66804 Negative_regulation of Negative_regulation of Tnf 4 0.56 2.79 2.26
82 INT114898 Regulation of Transcription of TNF 4 0.35 2.69 2.18
83 INT222609 Binding of Tlr4 8 0.43 4.03 1.98
84 INT122649 Positive_regulation of Regulation of Tnf 2 0.49 2.78 1.96
85 INT326816 Negative_regulation of Positive_regulation of Tlr4 2 0.59 3.96 1.95
86 INT295469 Localization of Tlr4 3 0.75 2.22 1.88
87 INT61845 Transcription of Homer1 9 0.72 2.28 1.85
88 INT77656 Gene_expression of Hsp90aa1 12 0.78 24.27 1.81
89 INT56216 Positive_regulation of Tnnt3 10 0.67 6.72 1.81
90 INT77801 Negative_regulation of Binding of Tnf 5 0.42 3.93 1.77
91 INT301954 Regulation of Negative_regulation of Tlr4 1 0.45 2.46 1.77
92 INT159957 Positive_regulation of Phosphorylation of Tnf 3 0.49 2.63 1.65
93 INT188584 Positive_regulation of Positive_regulation of TLR4 8 0.65 5.98 1.64
94 INT21565 Binding of Ikbkb 4 0.17 1.89 1.64
95 INT63520 Localization of Homer1 4 0.75 0.38 1.63
96 INT183791 Positive_regulation of Phosphorylation of TNF 6 0.49 4.72 1.56
97 INT61967 Positive_regulation of Negative_regulation of Tnf 3 0.50 2.46 1.49
98 INT68774 Positive_regulation of Ikbkb 2 0.21 0.99 1.39
99 INT82279 Regulation of Negative_regulation of Homer1 1 0.02 0 1.36
100 INT88855 Negative_regulation of Hsp90aa1 4 0.54 2.16 1.34
101 INT109688 Binding of TNNT1 6 0.47 4.01 1.25
102 INT228670 Negative_regulation of Rps6kb1 12 0.38 5.27 1.21
103 INT71370 Regulation of Ikbkb 3 0.12 1.69 1.08
104 INT168276 Negative_regulation of Phosphorylation of Tnf 1 0.19 1.3 1.08
105 INT100612 Positive_regulation of Hsp90aa1 4 0.64 5.3 1.01
106 INT118738 Transcription of Tlr4 4 0.70 1.39 1
107 INT88861 Positive_regulation of Gene_expression of Hsp90aa1 4 0.64 7.43 0.9
108 INT9797 Binding of Homer1 2 0.48 1.14 0.9
109 INT295466 Positive_regulation of Regulation of Tlr4 2 0.44 1.33 0.89
110 INT168278 Positive_regulation of Phosphorylation of Tlr4 1 0.48 1.05 0.88
111 INT168277 Phosphorylation of Tlr4 1 0.78 1.05 0.88
112 INT115822 Regulation of Transcription of Tnf 3 0.35 1.96 0.87
113 INT40520 Gene_expression of Ikbkb 3 0.30 1.51 0.86
114 INT136690 Regulation of Negative_regulation of Tnf 5 0.45 3.58 0.78
115 INT174069 Positive_regulation of Rps6kb1 14 0.61 3.7 0.77
116 INT188582 Positive_regulation of Transcription of TLR4 2 0.50 4.07 0.77
117 INT56214 Localization of Tnnt3 4 0.77 4.54 0.75
118 INT295465 Regulation of Positive_regulation of Tlr4 2 0.39 1.28 0.75
119 INT151128 Positive_regulation of Negative_regulation of Tlr4 2 0.46 1 0.75
120 INT122999 Gene_expression of Rps6kb1 16 0.67 3.45 0.71
121 INT161529 Regulation of Gene_expression of Tlr4 3 0.45 2.7 0.69
122 INT112465 Binding of Rps6kb1 3 0.25 1.26 0.69
123 INT186800 Positive_regulation of Binding of TLR4 2 0.47 1.31 0.67
124 INT236785 Regulation of Positive_regulation of TLR4 1 0.32 1.28 0.66
125 INT191706 Positive_regulation of Gene_expression of TNNT1 5 0.49 3.61 0.64
126 INT51263 Regulation of Phosphorylation of TNF 2 0.26 1.06 0.63
127 INT39728 Regulation of TCAP 1 0.00 0 0.61
128 INT235079 Negative_regulation of Phosphorylation of TNF 2 0.41 1.16 0.6
129 INT88859 Transcription of Hsp90aa1 1 0.58 1.51 0.6
130 INT166086 Binding of Hsp90aa1 1 0.28 0.08 0.6
131 INT88857 Negative_regulation of Transcription of Hsp90aa1 1 0.36 1.52 0.6
132 INT76505 Positive_regulation of Transcription of Homer1 3 0.21 0.48 0.59
133 INT236786 Positive_regulation of Localization of TLR4 2 0.45 1.89 0.57
134 INT84854 Regulation of Transcription of Homer1 1 0.00 0.15 0.57
135 INT92523 Phosphorylation of Homer1 3 0.63 0.15 0.52
136 INT116553 Phosphorylation of Ikbkb 3 0.37 1.35 0.5
137 INT343888 Regulation of Regulation of TLR4 1 0.25 1.34 0.49
138 INT106843 Regulation of Tnnt3 2 0.61 1.76 0.48
139 INT56215 Positive_regulation of Positive_regulation of Tnnt3 2 0.45 1.26 0.47
140 INT202063 Regulation of Binding of TLR4 2 0.44 2.14 0.47
141 INT87460 Gene_expression of Tnnt3 4 0.60 2.71 0.46
142 INT88856 Negative_regulation of Gene_expression of Hsp90aa1 2 0.39 2.31 0.45
143 INT85589 Positive_regulation of Positive_regulation of TNNT1 3 0.49 2.5 0.44
144 INT263820 Phosphorylation of RPS6KB1 6 0.52 1.43 0.42
145 INT72086 Regulation of Regulation of Tnf 1 0.45 0.3 0.4
146 INT80914 Negative_regulation of TNNT1 1 0.41 1.33 0.37
147 INT278150 Positive_regulation of Negative_regulation of Ikbkb 1 0.22 0.81 0.37
148 INT90876 Negative_regulation of RPS6KB1 2 0.47 1.29 0.36
149 INT56212 Regulation of Localization of Tnnt3 1 0.21 0.82 0.35
150 INT56213 Positive_regulation of Localization of Tnnt3 1 0.40 0.8 0.35
151 INT118736 Positive_regulation of Transcription of Tlr4 1 0.49 0.42 0.35
152 INT122996 Positive_regulation of Phosphorylation of Rps6kb1 9 0.58 1.53 0.34
153 INT278148 Negative_regulation of Gene_expression of Ikbkb 1 0.19 0.64 0.34
154 INT140475 Positive_regulation of Binding of TNNT1 1 0.49 0.85 0.34
155 INT143535 Protein_catabolism of Tnf 2 0.86 3.43 0.33
156 INT288041 Negative_regulation of Positive_regulation of TNNT1 1 0.41 0.15 0.32
157 INT77654 Regulation of Gene_expression of Hsp90aa1 4 0.62 2.41 0.28
158 INT281599 Localization of Rps6kb1 2 0.59 0.61 0.28
159 INT157768 Negative_regulation of Binding of TLR4 1 0.43 0.29 0.27
160 INT278153 Regulation of Negative_regulation of Ikbkb 1 0.20 0.65 0.27
161 INT310565 Regulation of Localization of TNNT1 1 0.44 0.65 0.25
162 INT301950 Regulation of Regulation of Tlr4 1 0.40 0.32 0.23
163 INT281588 Negative_regulation of Localization of Rps6kb1 2 0.33 0.16 0.22
164 INT278149 Localization of Ikbkb 1 0.33 0.97 0.22
165 INT194643 Positive_regulation of Regulation of TNF 2 0.28 2.4 0.21
166 INT81351 Negative_regulation of Regulation of TNF 1 0.33 0.23 0.21
167 INT348772 Positive_regulation of Positive_regulation of Tlr4 1 0.61 0.72 0.21
168 INT113131 Transcription of TNNT1 1 0.52 0.73 0.21
169 INT106842 Negative_regulation of Localization of Tnnt3 1 0.51 0.2 0.2
170 INT270722 Regulation of Positive_regulation of RPS6KB1 2 0.49 1.07 0.19
171 INT228901 Positive_regulation of RPS6KB1 5 0.55 2.44 0.18
172 INT251578 Positive_regulation of Protein_catabolism of TNF 1 0.41 0.26 0.16
173 INT285435 Protein_catabolism of TLR4 2 0.62 0.9 0.14
174 INT246424 Negative_regulation of Transcription of TLR4 2 0.41 0.52 0.14
175 INT257862 Negative_regulation of Positive_regulation of Rps6kb1 3 0.38 1.24 0.13
176 INT170142 Regulation of Protein_catabolism of Tnf 1 0.44 1.53 0.13
177 INT285441 Regulation of Localization of TLR4 2 0.38 0.15 0.12
178 INT46335 Regulation of Rps6kb1 8 0.40 2.39 0.11
179 INT278151 Negative_regulation of Negative_regulation of Ikbkb 1 0.19 0.61 0.11
180 INT228902 Gene_expression of RPS6KB1 5 0.75 2.32 0.1
181 INT295324 Regulation of Binding of Tnf 2 0.44 1.11 0.09
182 INT265969 Regulation of TNNI2 1 0.45 1.35 0.09
183 INT349555 Positive_regulation of Localization of Rps6kb1 1 0.39 0.45 0.09
184 INT122998 Positive_regulation of Gene_expression of Rps6kb1 2 0.60 0.62 0.08
185 INT284331 Positive_regulation of Phosphorylation of RPS6KB1 5 0.32 0.7 0.05
186 INT263818 Negative_regulation of Phosphorylation of RPS6KB1 1 0.01 0.43 0.05
187 INT242899 Negative_regulation of Negative_regulation of TLR4 1 0.20 0.09 0.05
188 INT231780 Regulation of Transcription of TLR4 1 0.19 0.62 0.04
189 INT337400 Negative_regulation of Localization of TNNT1 1 0.42 0.07 0.03
190 INT257851 Regulation of Phosphorylation of Rps6kb1 1 0.40 0.95 0.03
191 INT228900 Positive_regulation of Gene_expression of RPS6KB1 2 0.49 1.6 0
192 INT351115 Negative_regulation of Binding of RPS6KB1 1 0.34 0.29 0
193 INT289570 Positive_regulation of Regulation of Rps6kb1 1 0.24 0.06 0
194 INT351117 Binding of RPS6KB1 1 0.30 0.77 0
195 INT211656 Binding of Tnni2 1 0.30 0.58 0
196 INT211668 Binding of Tnni2 1 0.03 0.64 0
197 INT253407 Negative_regulation of Gene_expression of Rps6kb1 1 0.29 0 0
198 INT211631 Positive_regulation of Gene_expression of Tnni2 1 0.58 0.37 0
199 INT265970 Binding of TNNI2 1 0.37 0.2 0
200 INT337311 Negative_regulation of Positive_regulation of TLR4 1 0.35 0 0
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