GO:0003085

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Name negative regulation of systemic arterial blood pressure
Categary Process
Go Slim No
Go Link GO:0003085
Unique Molecular Interactions 90
Total Molecular Interactions 129
Total Single Events 774
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of systemic arterial blood pressure. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of systemic arterial blood pressure. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT141373 Ier3 Positive_regulation of CREM 1 0.00 0 0.95
2 INT22726 Positive_regulation of Ahr Positive_regulation of Hrtrt1 1 0.22 0.18 0.95
3 INT22725 Ahr Positive_regulation of Hrtrt1 1 0.22 0.18 0.95
4 INT303691 KNG1 Positive_regulation of AHR 1 0.03 0.98 0.69
5 INT303689 Regulation of KNG1 Positive_regulation of AHR 1 0.03 0.99 0.69
6 INT208372 Il13 Positive_regulation of Ahr 1 0.21 1.22 0.59
7 INT147575 Binding of Ahr and Cyp1a1 2 0.15 0.15 0.54
8 INT55445 Positive_regulation of Ahr Regulation of Mme 1 0.23 0 0.53
9 INT147576 Positive_regulation of Ahr Positive_regulation of Gene_expression of Scrg1 1 0.00 0.17 0.52
10 INT171897 Binding of Bmpr2 and Il1 1 0.03 0.84 0.52
11 INT162500 AHR Regulation of CYP1A1 3 0.19 0.18 0.51
12 INT162503 AHR Regulation of CYP1A2 3 0.61 0.18 0.5
13 INT162499 Binding of AHR and NEUROD1 3 0.25 0.19 0.49
14 INT115914 AHR Regulation of Gene_expression of PPIG 1 0.25 0.36 0.44
15 INT115916 AHR Regulation of Gene_expression of SLC45A2 1 0.64 0.36 0.44
16 INT115915 AHR Regulation of Gene_expression of CYP2B6 1 0.06 0.36 0.43
17 INT127077 Gdnf Positive_regulation of Gene_expression of IER3 1 0.02 0.26 0.42
18 INT127079 Gene_expression of Gdnf Positive_regulation of Gene_expression of IER3 1 0.02 0.26 0.42
19 INT127078 Bdnf Positive_regulation of Gene_expression of IER3 1 0.02 0.26 0.42
20 INT127076 Gene_expression of Bdnf Positive_regulation of Gene_expression of IER3 1 0.03 0.26 0.42
21 INT81991 Bmpr2 Positive_regulation of Gene_expression of ODF1 1 0.03 1.59 0.41
22 INT224894 Bdnf Positive_regulation of Positive_regulation of IER3 1 0.00 0.36 0.41
23 INT194860 BMPR2 Positive_regulation of IL1B 1 0.01 0.61 0.34
24 INT104932 AHR Positive_regulation of CYP1A1 1 0.43 0.83 0.31
25 INT139125 Adcyap1 Regulation of Ier3 1 0.54 0.8 0.29
26 INT279959 Tnfrsf1b Negative_regulation of Ahr 1 0.10 0.98 0.24
27 INT179186 Fcer2a Regulation of Positive_regulation of Ahr 1 0.05 1.23 0.23
28 INT70182 PRCP Positive_regulation of IER3 1 0.15 0.1 0.22
29 INT304104 Il13 Positive_regulation of Positive_regulation of AHR 1 0.14 2.6 0.19
30 INT188921 Binding of Pc and Ahr 1 0.12 0 0.19
31 INT188920 Pc Positive_regulation of Ahr 1 0.14 0 0.18
32 INT134196 Ahr Regulation of Transcription of Cyp1a1 1 0.11 0.14 0.16
33 INT251347 Binding of Bmpr2 and Limk1 1 0.18 1.51 0.16
34 INT134202 Ahr Regulation of AHR 1 0.18 0.13 0.16
35 INT153785 AHR Regulation of UGT1A3 1 0.69 0.07 0.14
36 INT36376 Binding of AHR and FUT4 1 0.01 0.9 0.14
37 INT304094 Binding of AHR and SNRNP70 1 0.00 2.64 0.14
38 INT338419 Il13 Regulation of Positive_regulation of Ahr 1 0.04 0.54 0.13
39 INT173129 PTGS2 Regulation of IER3 1 0.01 0.36 0.12
40 INT36373 Binding of AHR and INSL3 1 0.00 0.5 0.12
41 INT173119 PPA1 Regulation of IER3 1 0.00 0.36 0.12
42 INT336632 Ecm1 Regulation of Regulation of Ahr 1 0.03 0.61 0.11
43 INT325222 Il13 Regulation of Ahr 1 0.21 0.58 0.11
44 INT227061 Binding of Ahr and Alb 1 0.23 0.08 0.1
45 INT134201 Positive_regulation of Binding of AHR and Cyp1a1 1 0.21 0.07 0.1
46 INT134200 Binding of AHR and Cyp1a1 1 0.16 0.07 0.1
47 INT189550 Binding of BMPR2 and PAH 1 0.06 2.68 0.08
48 INT36372 Binding of AHR and KLF1 1 0.00 0.45 0.07
49 INT302985 HIVEP1 Positive_regulation of Positive_regulation of AHR 1 0.06 0.5 0.06
50 INT302984 MBP Positive_regulation of AHR 1 0.31 0.3 0.06
51 INT218009 AHR Positive_regulation of CYP27B1 1 0.16 0.06 0.05
52 INT285388 Ahr Positive_regulation of Gene_expression of Cyp27b1 1 0.01 0.14 0.04
53 INT218011 AHR Positive_regulation of Transcription of CYP27B1 1 0.16 0 0.04
54 INT285386 Ahr Positive_regulation of Binding of Cyp27b1 1 0.01 0.14 0.04
55 INT319218 Bmpr2 Negative_regulation of Smad2 1 0.17 0.12 0.03
56 INT197296 Ahr Regulation of Bhlha15 1 0.48 0.47 0.03
57 INT319219 Bmpr2 Positive_regulation of Smad1 1 0.18 0.29 0.03
58 INT229098 Binding of TP53 and IER3 1 0.01 1.47 0.03
59 INT319217 Bmpr2 Positive_regulation of Gene_expression of Smad1 1 0.19 0.11 0.03
60 INT219423 Binding of AHR and ARNT 4 0.24 0.46 0
61 INT205409 Binding of BMP6 and BMPR2 1 0.07 0.05 0
62 INT200058 Binding of Ndn and Bbs4 1 0.30 0.29 0
63 INT219418 ARNT Positive_regulation of Localization of AHR 1 0.25 0 0
64 INT310186 Binding of Gdf2 and Bmpr2 1 0.02 0 0
65 INT340275 NFATC1 Positive_regulation of Binding of Ahr 1 0.10 0.51 0
66 INT272132 IER3 Regulation of Transcription of Ie 1 0.00 0.71 0
67 INT200062 Binding of Ngfr and Bbs4 1 0.30 0.3 0
68 INT219503 Binding of AHR and Ppib 1 0.27 0 0
69 INT219406 AHR Positive_regulation of CBL 1 0.03 0.65 0
70 INT205410 Binding of BMP2 and BMPR2 1 0.07 0.05 0
71 INT189127 Mch Positive_regulation of Ahr 1 0.18 0.29 0
72 INT197304 Ahr Regulation of Hes1 1 0.06 0.17 0
73 INT197295 Positive_regulation of Binding of Ahr and Cyp1a1 1 0.20 0 0
74 INT310187 Acvrl1 Regulation of Gene_expression of Bmpr2 1 0.04 0 0
75 INT330384 IER3 Regulation of USH2A 1 0.00 0.87 0
76 INT219504 AHR Regulation of Gene_expression of Ppib 1 0.21 1.12 0
77 INT186889 Binding of AHR and PC 1 0.05 1.06 0
78 INT353194 ARNTL Regulation of Localization of Ahr 1 0.27 0.32 0
79 INT219424 Binding of AHR and TSPO 1 0.01 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of systemic arterial blood pressure. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of systemic arterial blood pressure. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT90603 Positive_regulation of Ahr 103 0.69 58.65 7.73
2 INT14166 Positive_regulation of Ahr 32 0.61 20.78 7.47
3 INT14165 Negative_regulation of Ahr 14 0.51 8.35 4.17
4 INT115921 Positive_regulation of AHR 22 0.49 12.03 3.53
5 INT66585 Gene_expression of IER3 13 0.63 7.39 3.48
6 INT147572 Gene_expression of Ahr 73 0.75 38.99 3.15
7 INT47207 Negative_regulation of Ahr 25 0.52 16.11 3.02
8 INT44661 Regulation of Ahr 15 0.45 12.69 2.79
9 INT96876 Gene_expression of AHR 20 0.77 10.43 2.39
10 INT68767 Positive_regulation of IER3 6 0.28 2.59 1.8
11 INT96877 Transcription of AHR 7 0.62 3.25 1.77
12 INT134197 Regulation of AHR 11 0.44 4.82 1.76
13 INT14167 Negative_regulation of Positive_regulation of Ahr 5 0.51 1.54 1.71
14 INT95253 Regulation of IER3 4 0.23 1.89 1.6
15 INT232644 Transcription of IER3 1 0.01 0.97 1.58
16 INT81982 Gene_expression of Bmpr2 36 0.60 14.58 1.55
17 INT36389 Binding of AHR 18 0.45 7.22 1.46
18 INT90604 Positive_regulation of Positive_regulation of Ahr 8 0.45 3.52 1.45
19 INT54805 Regulation of Ahr 7 0.22 4.14 1.41
20 INT3816 Gene_expression of Ahr 13 0.65 7.51 1.31
21 INT29693 Binding of Ahr 11 0.31 13.27 1.23
22 INT45079 Binding of Ahr 21 0.44 10.07 1
23 INT95252 Regulation of Positive_regulation of IER3 1 0.03 0.73 0.78
24 INT208367 Regulation of Localization of Ahr 1 0.30 1.6 0.67
25 INT208371 Localization of Ahr 2 0.50 1.9 0.66
26 INT82542 Negative_regulation of Gene_expression of IER3 3 0.13 0.16 0.65
27 INT114942 Negative_regulation of Positive_regulation of Ahr 5 0.55 2.65 0.62
28 INT64096 Negative_regulation of AHR 5 0.37 1.2 0.58
29 INT110924 Regulation of BMPR2 3 0.17 1.75 0.54
30 INT147571 Regulation of Binding of Ahr 1 0.26 0.15 0.54
31 INT104935 Localization of AHR 6 0.74 2.54 0.53
32 INT186728 Negative_regulation of Positive_regulation of AHR 1 0.08 1.61 0.52
33 INT141364 Positive_regulation of Positive_regulation of Ier3 1 0.00 0 0.48
34 INT141363 Positive_regulation of Ier3 1 0.00 0 0.47
35 INT94035 Transcription of Ahr 1 0.53 0.53 0.43
36 INT279958 Regulation of Regulation of Ahr 1 0.29 1.32 0.37
37 INT197286 Positive_regulation of Gene_expression of Ahr 10 0.67 9.78 0.36
38 INT150330 Gene_expression of BMPR2 7 0.29 4.22 0.34
39 INT251324 Binding of Bmpr2 5 0.23 2.99 0.34
40 INT201967 Positive_regulation of Bmpr2 4 0.31 1.24 0.34
41 INT96871 Regulation of Transcription of AHR 2 0.41 0.46 0.33
42 INT115922 Negative_regulation of Binding of AHR 1 0.40 0.12 0.32
43 INT139124 Transcription of Ier3 1 0.61 0.81 0.29
44 INT145538 Localization of IER3 3 0.12 0.5 0.28
45 INT153731 Positive_regulation of Gene_expression of Ahr 2 0.32 2 0.28
46 INT251327 Regulation of Binding of Bmpr2 1 0.20 2.27 0.27
47 INT55443 Positive_regulation of Positive_regulation of Ahr 1 0.40 0 0.26
48 INT96869 Positive_regulation of Gene_expression of AHR 1 0.45 0.43 0.23
49 INT81981 Negative_regulation of Bmpr2 4 0.27 2.88 0.21
50 INT199771 Localization of Ahr 8 0.70 4.86 0.2
51 INT150332 Negative_regulation of Gene_expression of BMPR2 1 0.01 0 0.2
52 INT150331 Positive_regulation of Gene_expression of BMPR2 2 0.02 0.59 0.19
53 INT123935 Positive_regulation of BMPR2 3 0.26 1.65 0.18
54 INT96875 Regulation of Gene_expression of AHR 1 0.25 0.38 0.18
55 INT134193 Regulation of Regulation of Ahr 1 0.12 0.14 0.16
56 INT189604 Negative_regulation of BMPR2 2 0.26 0.95 0.15
57 INT289312 Phosphorylation of Ahr 1 0.03 0.86 0.15
58 INT192082 Localization of BMPR2 1 0.32 0.55 0.15
59 INT153787 Positive_regulation of Transcription of AHR 1 0.45 0.08 0.15
60 INT294583 Negative_regulation of Gene_expression of Ahr 2 0.38 1.01 0.14
61 INT134194 Regulation of Gene_expression of Ahr 1 0.12 0.17 0.14
62 INT166623 Binding of BMPR2 1 0.29 0.35 0.13
63 INT163225 Gene_expression of Bbs4 1 0.60 0.09 0.13
64 INT197287 Regulation of Gene_expression of Ahr 5 0.45 1 0.11
65 INT201962 Transcription of Bmpr2 6 0.37 3.51 0.09
66 INT289311 Negative_regulation of Gene_expression of Ahr 1 0.02 1 0.09
67 INT134198 Positive_regulation of Binding of AHR 1 0.40 0.07 0.09
68 INT339153 Negative_regulation of Localization of AHR 1 0.06 1.09 0.08
69 INT254332 Negative_regulation of Gene_expression of Bmpr2 3 0.22 2.41 0.07
70 INT195858 Transcription of Ahr 2 0.69 1.33 0.07
71 INT195859 Positive_regulation of Transcription of Ahr 2 0.48 0.73 0.07
72 INT199780 Positive_regulation of Localization of Ahr 2 0.45 1.03 0.07
73 INT197288 Regulation of Positive_regulation of Ahr 1 0.59 0.45 0.07
74 INT340266 Negative_regulation of Binding of Ahr 1 0.16 1.33 0.06
75 INT329427 Binding of Ier3 1 0.31 0.7 0.05
76 INT294584 Negative_regulation of Negative_regulation of Ahr 1 0.38 0.56 0.04
77 INT306285 Positive_regulation of Gene_expression of IER3 1 0.15 1.13 0.03
78 INT278039 Phosphorylation of BMPR2 1 0.08 0.26 0.03
79 INT278022 Phosphorylation of Bmpr2 1 0.21 0.27 0.03
80 INT302312 Localization of Bmpr2 4 0.46 0.47 0
81 INT219929 Positive_regulation of Gene_expression of Bmpr2 3 0.15 0.9 0
82 INT177821 Negative_regulation of Gene_expression of AHR 1 0.30 0.54 0
83 INT319209 Regulation of Positive_regulation of Bmpr2 1 0.28 0.08 0
84 INT189623 Transcription of BMPR2 1 0.32 0.71 0
85 INT355333 Regulation of Transcription of Bmpr2 1 0.03 0.15 0
86 INT296536 Gene_expression of Ier3 1 0.04 1.19 0
87 INT211502 Negative_regulation of Negative_regulation of AHR 1 0.15 0 0
88 INT296568 Regulation of Gene_expression of Ier3 1 0.02 1.26 0
89 INT310165 Negative_regulation of Transcription of Bmpr2 1 0.22 2.1 0
90 INT319208 Regulation of Bmpr2 1 0.28 0.08 0
91 INT187311 Regulation of Positive_regulation of AHR 1 0.28 0 0
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