GO:0003130

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Name BMP signaling pathway involved in heart induction
Categary Process
Go Slim No
Go Link GO:0003130
Unique Molecular Interactions 55
Total Molecular Interactions 90
Total Single Events 915
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for BMP signaling pathway involved in heart induction. They are ordered first by their pain relevance and then by number of times they were reported for BMP signaling pathway involved in heart induction. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT210783 Bmp2 Positive_regulation of Tnip1 1 0.40 0.53 0.94
2 INT210791 Bmp2 Positive_regulation of Net1 1 0.38 0.52 0.93
3 INT210799 Bmp2 Positive_regulation of B2m 1 0.35 0.52 0.92
4 INT210793 Bmp2 Positive_regulation of Tsc22d3 1 0.32 0.26 0.46
5 INT285935 IL6 Positive_regulation of Gene_expression of POU5F1 1 0.14 2.68 0.37
6 INT224687 Il1 Positive_regulation of Bmp2 1 0.00 0.3 0.31
7 INT166165 Binding of TGFB3 and Bmp2 1 0.00 0 0.3
8 INT182817 EEF1A2 Positive_regulation of BMP2 1 0.26 1.62 0.28
9 INT287894 VEGFA Positive_regulation of Localization of BMP4 1 0.04 2.49 0.2
10 INT326974 BMP2 Positive_regulation of Gene_expression of COL2A1 1 0.07 0.27 0.11
11 INT287887 WNT1 Positive_regulation of Localization of BMP4 1 0.04 1.13 0.1
12 INT238038 Binding of BMP2 and OPLL 1 0.20 2.45 0.09
13 INT297968 Positive_regulation of Binding of BMP2 and IL17C 1 0.21 0.26 0.08
14 INT297970 Binding of BMP2 and IL17C 1 0.15 0.26 0.08
15 INT295122 Bmp2 Regulation of Grxcr1 1 0.02 0.66 0.06
16 INT295120 Bmp2 Regulation of Transcription of Pou1f1 1 0.24 0.66 0.06
17 INT282552 POU5F1 Positive_regulation of FGF4 1 0.29 0.29 0.05
18 INT210261 Bmp4 Regulation of Gene_expression of Tff3 1 0.64 0 0.05
19 INT282555 POU5F1 Positive_regulation of Positive_regulation of MAPK1 1 0.11 0.28 0.04
20 INT282556 POU5F1 Positive_regulation of GOPC 1 0.06 0.06 0.04
21 INT285936 IL17A Positive_regulation of Gene_expression of POU5F1 1 0.10 0.34 0.04
22 INT282561 POU5F1 Positive_regulation of Gene_expression of NANOG 1 0.11 0.26 0.04
23 INT306560 BMP4 Positive_regulation of MAPK1 1 0.09 0.09 0.03
24 INT282543 KDM4C Regulation of POU5F1 1 0.06 0.08 0.03
25 INT173613 BMP2 Positive_regulation of INCENP 1 0.00 0.28 0.03
26 INT282542 KDM3A Regulation of POU5F1 1 0.06 0.08 0.03
27 INT287233 PDLIM7 Positive_regulation of Gene_expression of BMP2 1 0.07 0.12 0.03
28 INT282553 POU5F1 Positive_regulation of REXO1 1 0.21 0.1 0.03
29 INT343999 INCENP Positive_regulation of BMP2 1 0.01 0 0
30 INT278021 BMP2 Positive_regulation of Gene_expression of RUNX1T1 1 0.02 0.5 0
31 INT282559 NANOG Regulation of POU5F1 1 0.14 0.45 0
32 INT282554 Binding of POU5F1 and SOX2 1 0.19 0.1 0
33 INT205451 Binding of BMP2 and Acvr2a 1 0.02 0.05 0
34 INT282551 SOX2 Regulation of POU5F1 1 0.24 0.45 0
35 INT196023 Bmp2 Negative_regulation of Gene_expression of Bmp4 1 0.09 0.07 0
36 INT205410 Binding of BMP2 and BMPR2 1 0.07 0.05 0
37 INT282541 SOX2 Regulation of Transcription of POU5F1 1 0.24 0.05 0
38 INT344001 INCENP Positive_regulation of Gene_expression of BMP2 1 0.01 0 0
39 INT196021 Bmp2 Positive_regulation of Gene_expression of Bmp4 1 0.09 0.08 0
40 INT282558 POU5F1 Positive_regulation of MAPK1 1 0.16 0.26 0
41 INT282607 POU5F1 Positive_regulation of Mdk 1 0.08 0.26 0
42 INT285946 IL6 Regulation of POU5F1 1 0.05 0.12 0
43 INT295129 Proc Regulation of Bmp2 1 0.00 0.48 0
44 INT196022 Bmp7 Regulation of Bmp4 1 0.06 0.06 0
45 INT282549 POU5F1 Regulation of Transcription of SOX2 1 0.32 0.05 0
46 INT282539 POU5F1 Regulation of Gene_expression of NANOG 1 0.17 0 0
47 INT321594 Bmp2 Regulation of Gene_expression of Lxn 1 0.42 1.71 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for BMP signaling pathway involved in heart induction. They are ordered first by their pain relevance and then by number of times they were reported in BMP signaling pathway involved in heart induction. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT154527 Gene_expression of POU5F1 180 0.78 34.01 4.34
2 INT85809 Gene_expression of BMP2 46 0.78 9.91 3.05
3 INT96423 Gene_expression of Bmp2 61 0.78 25.07 3.01
4 INT120088 Gene_expression of Bmp4 37 0.73 13.89 1.73
5 INT130014 Positive_regulation of BMP2 11 0.66 5.34 1.42
6 INT282590 Positive_regulation of Gene_expression of POU5F1 40 0.70 8.42 1.32
7 INT70619 Regulation of Bmp2 6 0.60 3.1 1.29
8 INT282572 Positive_regulation of POU5F1 24 0.70 5.8 1.13
9 INT96424 Transcription of Bmp2 6 0.69 6.34 1.11
10 INT160538 Binding of Bmp2 4 0.40 2.08 1.07
11 INT114664 Binding of BMP2 12 0.37 6.54 0.91
12 INT142122 Regulation of Gene_expression of Bmp4 5 0.43 2.69 0.86
13 INT210247 Positive_regulation of Bmp4 6 0.65 4.36 0.8
14 INT282599 Regulation of Gene_expression of POU5F1 10 0.62 4.89 0.71
15 INT96422 Gene_expression of Bmp4 18 0.69 3.26 0.63
16 INT238049 Positive_regulation of Gene_expression of BMP2 8 0.51 2.06 0.59
17 INT85808 Localization of BMP2 7 0.77 1.94 0.51
18 INT145301 Regulation of Gene_expression of Bmp2 1 0.32 1.16 0.48
19 INT230634 Negative_regulation of POU5F1 10 0.43 1.03 0.46
20 INT142124 Binding of Bmp4 1 0.35 0.46 0.45
21 INT120086 Gene_expression of Bmp2 5 0.27 2.34 0.43
22 INT180688 Transcription of Bmp4 3 0.58 0.35 0.41
23 INT180702 Positive_regulation of Transcription of Bmp4 3 0.42 0.35 0.41
24 INT84945 Transcription of BMP2 5 0.61 1.8 0.36
25 INT196026 Positive_regulation of Gene_expression of Bmp2 14 0.69 3.19 0.35
26 INT159213 Gene_expression of BMP4 8 0.74 2.1 0.28
27 INT159212 Positive_regulation of Gene_expression of BMP4 2 0.66 0.91 0.28
28 INT282571 Negative_regulation of Positive_regulation of POU5F1 1 0.38 0 0.28
29 INT185009 Negative_regulation of BMP4 2 0.56 1.04 0.25
30 INT145305 Positive_regulation of Bmp2 12 0.69 8.65 0.24
31 INT109699 Regulation of BMP2 5 0.43 2.21 0.23
32 INT142121 Positive_regulation of Gene_expression of Bmp4 3 0.47 7 0.21
33 INT120085 Negative_regulation of Gene_expression of Bmp4 5 0.55 0.61 0.17
34 INT148064 Localization of Bmp2 2 0.29 0.14 0.17
35 INT282576 Negative_regulation of Gene_expression of POU5F1 12 0.43 2.79 0.16
36 INT106010 Positive_regulation of Bmp2 2 0.26 0.91 0.15
37 INT278790 Binding of POU5F1 8 0.43 0.67 0.11
38 INT254992 Negative_regulation of Gene_expression of BMP2 3 0.34 0.56 0.11
39 INT238044 Positive_regulation of Transcription of BMP2 2 0.43 0.83 0.11
40 INT326976 Regulation of Localization of BMP2 1 0.59 0.08 0.1
41 INT287912 Localization of BMP4 1 0.18 1.13 0.1
42 INT196035 Localization of Bmp2 3 0.63 0.23 0.09
43 INT196033 Negative_regulation of Gene_expression of Bmp4 3 0.21 0.45 0.09
44 INT278036 Negative_regulation of BMP2 2 0.34 0.64 0.09
45 INT114663 Regulation of Binding of BMP2 1 0.38 0.19 0.09
46 INT163072 Regulation of Binding of Bmp2 1 0.30 0.52 0.08
47 INT278785 Positive_regulation of Binding of POU5F1 2 0.45 0.19 0.07
48 INT210243 Negative_regulation of Bmp4 1 0.55 0.55 0.07
49 INT216377 Transcription of POU5F1 9 0.69 0.58 0.05
50 INT196025 Negative_regulation of Bmp2 2 0.34 0.14 0.05
51 INT282603 Positive_regulation of Positive_regulation of POU5F1 1 0.45 0 0.05
52 INT196030 Positive_regulation of Bmp4 6 0.62 2.55 0.04
53 INT229753 Positive_regulation of Gene_expression of Bmp2 2 0.11 1.22 0.04
54 INT210238 Positive_regulation of Negative_regulation of Bmp4 1 0.47 0 0.04
55 INT287236 Positive_regulation of Positive_regulation of BMP2 1 0.29 0.08 0.04
56 INT253182 Positive_regulation of Positive_regulation of Bmp4 1 0.45 0.58 0.04
57 INT282944 Negative_regulation of Negative_regulation of POU5F1 1 0.11 0 0.03
58 INT282605 Regulation of POU5F1 4 0.55 0.4 0
59 INT196034 Positive_regulation of Gene_expression of Bmp4 4 0.45 0.63 0
60 INT260779 Negative_regulation of Bmp4 4 0.23 0.94 0
61 INT282585 Localization of POU5F1 3 0.67 0.08 0
62 INT189593 Regulation of Gene_expression of BMP2 2 0.33 0.8 0
63 INT196027 Binding of Bmp4 2 0.13 0.97 0
64 INT142119 Regulation of Bmp4 2 0.58 0.29 0
65 INT145300 Positive_regulation of Positive_regulation of Bmp2 2 0.34 1.03 0
66 INT196031 Binding of Bmp2 1 0.16 0 0
67 INT278808 Regulation of Binding of POU5F1 1 0.01 0 0
68 INT278735 Negative_regulation of Gene_expression of Bmp2 1 0.43 0.06 0
69 INT309646 Negative_regulation of Transcription of POU5F1 1 0.43 0 0
70 INT339667 Localization of Bmp4 1 0.38 0.27 0
71 INT278737 Positive_regulation of Transcription of Bmp2 1 0.47 1.4 0
72 INT120087 Negative_regulation of Gene_expression of Bmp2 1 0.11 0.14 0
73 INT294842 Positive_regulation of Negative_regulation of POU5F1 1 0.41 0.49 0
74 INT278040 Negative_regulation of Localization of BMP2 1 0.32 0.32 0
75 INT351554 Negative_regulation of Gene_expression of BMP4 1 0.26 0 0
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