GO:0003143

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Name embryonic heart tube morphogenesis
Categary Process
Go Slim No
Go Link GO:0003143
Unique Molecular Interactions 35
Total Molecular Interactions 69
Total Single Events 148
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for embryonic heart tube morphogenesis. They are ordered first by their pain relevance and then by number of times they were reported for embryonic heart tube morphogenesis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT59396 Tead1 Negative_regulation of Negative_regulation of Man2a2 1 0.00 0 0.86
2 INT59395 Tead1 Negative_regulation of Man2a2 1 0.00 0 0.86
3 INT237453 Binding of STAR and MESP1 1 0.00 0.47 0.42
4 INT30068 Tead1 Positive_regulation of Localization of Avp 1 0.04 0 0.16
5 INT306238 Tead1 Regulation of Ins1 1 0.00 1.04 0.05
6 INT269943 Sox17 Regulation of Binding of Smad3 1 0.37 0.12 0
7 INT192046 Negative_regulation of Binding of RYR2 and Cbx5 1 0.01 1.12 0
8 INT269915 Binding of Smad2 and Sox17 1 0.21 0.07 0
9 INT273289 Binding of Psen2 and Ryr2 1 0.27 4.53 0
10 INT269919 Sox17 Negative_regulation of Binding of Smad3 1 0.36 0 0
11 INT269948 Sox17 Positive_regulation of Gene_expression of Ccnd1 1 0.61 0.19 0
12 INT269940 Binding of Sox17 and Scn4a 1 0.17 0.15 0
13 INT192049 Negative_regulation of Binding of RYR2 and Cbx1 1 0.01 1.12 0
14 INT269955 Positive_regulation of Binding of Smad3 and Sox17 1 0.39 0.05 0
15 INT269928 Binding of Sox17 and Mgst1 1 0.12 0 0
16 INT192045 Jup Positive_regulation of RYR2 1 0.11 0.29 0
17 INT269949 Sox17 Positive_regulation of Ccnd1 1 0.61 0.96 0
18 INT269954 Sox17 Regulation of Gene_expression of Foxa2 1 0.43 0 0
19 INT269950 Sox17 Negative_regulation of Gene_expression of Cdkn2b 1 0.27 0.24 0
20 INT269947 Sox17 Positive_regulation of Gene_expression of Atxn1 1 0.08 0 0
21 INT269957 Sox17 Negative_regulation of Gene_expression of TGFB1 1 0.04 0 0
22 INT269941 Sox17 Regulation of Gene_expression of Foxa1 1 0.56 0 0
23 INT269942 Sox17 Regulation of Smad3 1 0.37 0.12 0
24 INT269934 Sox17 Regulation of Gopc 1 0.12 0 0
25 INT269951 Binding of Sox17 and Gopc 1 0.11 0 0
26 INT192047 Binding of RYR2 and Cbx1 1 0.01 1.12 0
27 INT269930 Binding of Smad3 and Sox17 1 0.40 1.16 0
28 INT269945 Sox17 Positive_regulation of Localization of Ccnd1 1 0.39 0 0
29 INT192043 Binding of RYR2 and Cbx5 1 0.01 1.12 0
30 INT192048 Binding of DSP and Ryr2 1 0.24 1.1 0
31 INT269922 Sox17 Regulation of Ccnd1 1 0.47 0 0
32 INT269931 Binding of Ccnd1 and Sox17 1 0.33 0.19 0
33 INT269918 Binding of Scn5a and Sox17 1 0.18 0.15 0
34 INT269916 Sox17 Positive_regulation of Pcna 1 0.16 0 0
35 INT192042 Binding of Jup and Ryr2 1 0.17 1.09 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for embryonic heart tube morphogenesis. They are ordered first by their pain relevance and then by number of times they were reported in embryonic heart tube morphogenesis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT237456 Gene_expression of MESP1 1 0.03 1.33 1.12
2 INT42339 Gene_expression of Tead1 4 0.31 0.56 0.8
3 INT57881 Binding of Tead1 2 0.25 1.63 0.7
4 INT31653 Positive_regulation of Tead1 4 0.47 0.25 0.66
5 INT192006 Gene_expression of RYR2 5 0.23 7.69 0.44
6 INT237457 Positive_regulation of Gene_expression of MESP1 1 0.02 0.45 0.4
7 INT120216 Regulation of RYR2 2 0.28 1.03 0.22
8 INT90480 Negative_regulation of Tead1 4 0.37 1.37 0.18
9 INT165787 Positive_regulation of RYR2 2 0.23 1.3 0.11
10 INT192016 Localization of RYR2 5 0.25 4.18 0.05
11 INT192012 Binding of RYR2 2 0.30 3.61 0.05
12 INT221865 Positive_regulation of Localization of RYR2 2 0.15 4.56 0.05
13 INT192023 Negative_regulation of RYR2 1 0.15 1.86 0.04
14 INT322462 Transcription of Ryr2 1 0.55 0.47 0.03
15 INT219581 Binding of Ryr2 2 0.27 4.54 0
16 INT200864 Positive_regulation of Sox17 2 0.50 0.07 0
17 INT219567 Phosphorylation of Ryr2 2 0.62 0.22 0
18 INT269903 Localization of Sox17 1 0.75 0.07 0
19 INT269907 Positive_regulation of Localization of Sox17 1 0.50 0.2 0
20 INT219566 Localization of Ryr2 1 0.45 0.49 0
21 INT306234 Localization of Tead1 1 0.01 0.22 0
22 INT269904 Regulation of Sox17 1 0.45 0 0
23 INT269876 Binding of Sox17 1 0.48 0.72 0
24 INT269885 Negative_regulation of Sox17 1 0.42 0.32 0
25 INT269891 Positive_regulation of Gene_expression of Sox17 1 0.69 0.4 0
26 INT322461 Negative_regulation of Transcription of Ryr2 1 0.45 0 0
27 INT219582 Positive_regulation of Phosphorylation of Ryr2 1 0.30 0.22 0
28 INT269878 Negative_regulation of Gene_expression of Sox17 1 0.42 0 0
29 INT192020 Regulation of Localization of RYR2 1 0.15 0.27 0
30 INT269892 Transcription of Sox17 1 0.71 0 0
31 INT269898 Positive_regulation of Binding of Sox17 1 0.44 0 0
32 INT269869 Gene_expression of Sox17 1 0.77 2.48 0
33 INT297204 Regulation of Ryr2 1 0.08 0.3 0
34 INT269882 Regulation of Gene_expression of Sox17 1 0.61 0.14 0
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