GO:0003166

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Name bundle of His development
Categary Process
Go Slim No
Go Link GO:0003166
Unique Molecular Interactions 30
Total Molecular Interactions 35
Total Single Events 129
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for bundle of His development. They are ordered first by their pain relevance and then by number of times they were reported for bundle of His development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT89878 Pdyn Positive_regulation of Gene_expression of Nkx2-5 1 0.35 0 1.29
2 INT89877 Pdyn Positive_regulation of Nkx2-5 1 0.11 0 0.64
3 INT283714 Positive_regulation of Binding of Id2 and Homer1 1 0.08 1.34 0.42
4 INT283713 Binding of Id2 and Homer1 1 0.06 1.34 0.42
5 INT109067 Pdyn Positive_regulation of Gene_expression of NKX2-5 1 0.01 0 0.29
6 INT283719 Id2 Regulation of Regulation of Hes7 1 0.00 0.31 0.12
7 INT283710 Binding of Id2 and Hes7 1 0.01 0.13 0.11
8 INT208938 Positive_regulation of Tacr1 Positive_regulation of Nkx2-5 1 0.17 0 0.1
9 INT129624 Bmp7 Positive_regulation of Gene_expression of Id2 1 0.26 0.31 0.08
10 INT129625 Id2 Positive_regulation of Gene_expression of Bmp7 1 0.24 0.31 0.08
11 INT208943 Nfkb1 Positive_regulation of Nkx2-5 1 0.11 0.38 0.08
12 INT283721 Binding of Lpin1 and Id2 1 0.38 0.18 0.08
13 INT129627 Bmp7 Positive_regulation of Id2 1 0.24 0.25 0.07
14 INT286563 Binding of Id2 and P1Ehs1 1 0.00 0.17 0.06
15 INT286591 Binding of PKD1 and Id2 1 0.07 0.17 0.06
16 INT208945 Nkx2-5 Positive_regulation of Gene_expression of Nppa 1 0.03 0.33 0.05
17 INT305383 Binding of NKX2-5 and FLNA 1 0.10 0.7 0.04
18 INT283720 Id2 Negative_regulation of Transcription of Cdkn2b 1 0.18 0.11 0.03
19 INT283722 Id2 Negative_regulation of Transcription of CDKN1A 1 0.45 0.11 0.03
20 INT283712 Id2 Regulation of Gene_expression of Fos 1 0.43 0 0.03
21 INT201534 RASSF1 Negative_regulation of ID2 1 0.33 1.41 0
22 INT314693 Binding of TBX2 and TBX5 1 0.16 0.84 0
23 INT201542 Positive_regulation of RASSF1 Negative_regulation of ID2 1 0.36 1.41 0
24 INT283717 Id2 Regulation of 4930579C15Rik 1 0.15 0.75 0
25 INT272520 Gene_expression of Dmpk Positive_regulation of Positive_regulation of Nkx2-5 1 0.02 0.43 0
26 INT283718 Binding of Id2 and Aatf 1 0.03 0.19 0
27 INT201536 RASSF1 Regulation of ID2 1 0.41 1.42 0
28 INT286590 Binding of ID2 and Pkd2 1 0.13 0.13 0
29 INT201533 RASSF1 Positive_regulation of Gene_expression of ID2 1 0.38 1.41 0
30 INT272521 Binding of DMPK and Nkx2-5 1 0.01 0.42 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for bundle of His development. They are ordered first by their pain relevance and then by number of times they were reported in bundle of His development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT129610 Gene_expression of Id2 7 0.74 17.07 1.69
2 INT89865 Gene_expression of Nkx2-5 14 0.75 2.99 1.58
3 INT161716 Localization of Nkx2-5 2 0.74 2.17 1.02
4 INT109075 Positive_regulation of Transcription of NKX2-5 1 0.67 0 1.02
5 INT109074 Transcription of NKX2-5 1 0.69 0 1.01
6 INT109062 Gene_expression of NKX2-5 7 0.75 3.31 0.82
7 INT89861 Negative_regulation of Nkx2-5 3 0.19 0.12 0.63
8 INT129615 Positive_regulation of Id2 2 0.66 2.22 0.57
9 INT89869 Negative_regulation of Gene_expression of Nkx2-5 1 0.41 0 0.56
10 INT142972 Gene_expression of ID2 6 0.54 5.92 0.49
11 INT305390 Negative_regulation of NKX2-5 2 0.37 2.24 0.49
12 INT283683 Binding of Id2 5 0.35 0.8 0.35
13 INT208915 Positive_regulation of Nkx2-5 3 0.29 1.02 0.25
14 INT129612 Positive_regulation of Gene_expression of Id2 4 0.67 3.61 0.22
15 INT305392 Binding of NKX2-5 1 0.22 0.93 0.21
16 INT208925 Positive_regulation of Localization of Nkx2-5 1 0.21 0.14 0.16
17 INT146415 Regulation of Nkx2-5 3 0.44 0.91 0.13
18 INT283702 Transcription of Id2 1 0.66 0.64 0.13
19 INT283708 Localization of Id2 2 0.71 0.72 0.11
20 INT142970 Positive_regulation of Gene_expression of ID2 2 0.40 2.39 0.11
21 INT142968 Negative_regulation of Gene_expression of ID2 1 0.19 0.98 0.11
22 INT208922 Transcription of Nkx2-5 2 0.29 0.36 0.1
23 INT323415 Regulation of NKX2-5 1 0.39 0.71 0.1
24 INT208917 Positive_regulation of Transcription of Nkx2-5 1 0.21 0 0.1
25 INT323416 Localization of NKX2-5 1 0.65 1.75 0.1
26 INT208918 Positive_regulation of Gene_expression of Nkx2-5 3 0.23 0.48 0.09
27 INT142971 Negative_regulation of Positive_regulation of ID2 1 0.20 0.69 0.09
28 INT142969 Positive_regulation of ID2 1 0.21 0.68 0.09
29 INT129614 Positive_regulation of Positive_regulation of Id2 1 0.48 0.31 0.08
30 INT305387 Positive_regulation of Gene_expression of NKX2-5 1 0.31 0.72 0.07
31 INT129613 Regulation of Gene_expression of Id2 1 0.43 0.24 0.06
32 INT262960 Gene_expression of TBX5 1 0.23 0.09 0.03
33 INT286577 Binding of ID2 1 0.19 0.12 0
34 INT283686 Regulation of Id2 1 0.26 0.31 0
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