GO:0003181

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Name atrioventricular valve morphogenesis
Categary Process
Go Slim No
Go Link GO:0003181
Unique Molecular Interactions 63
Total Molecular Interactions 96
Total Single Events 642
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for atrioventricular valve morphogenesis. They are ordered first by their pain relevance and then by number of times they were reported for atrioventricular valve morphogenesis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT89873 Pdyn Positive_regulation of Gene_expression of Gata4 1 0.23 0 1.29
2 INT89876 Pdyn Positive_regulation of Gata4 1 0.23 0 1.28
3 INT210783 Bmp2 Positive_regulation of Tnip1 1 0.40 0.53 0.94
4 INT210791 Bmp2 Positive_regulation of Net1 1 0.38 0.52 0.93
5 INT210799 Bmp2 Positive_regulation of B2m 1 0.35 0.52 0.92
6 INT109065 Pdyn Positive_regulation of Gene_expression of Gata4 1 0.00 0 0.58
7 INT210793 Bmp2 Positive_regulation of Tsc22d3 1 0.32 0.26 0.46
8 INT224687 Il1 Positive_regulation of Bmp2 1 0.00 0.3 0.31
9 INT166165 Binding of TGFB3 and Bmp2 1 0.00 0 0.3
10 INT182817 EEF1A2 Positive_regulation of BMP2 1 0.26 1.62 0.28
11 INT234992 Car2 Positive_regulation of Jup 1 0.02 0.27 0.2
12 INT201762 JUP Regulation of Gene_expression of Ccnd1 1 0.03 0.8 0.13
13 INT201791 JUP Regulation of Gene_expression of Myc 1 0.49 0.8 0.13
14 INT326974 BMP2 Positive_regulation of Gene_expression of COL2A1 1 0.07 0.27 0.11
15 INT238038 Binding of BMP2 and OPLL 1 0.20 2.45 0.09
16 INT297968 Positive_regulation of Binding of BMP2 and IL17C 1 0.21 0.26 0.08
17 INT297970 Binding of BMP2 and IL17C 1 0.15 0.26 0.08
18 INT339111 Binding of ERBB2 and JUP 1 0.38 0.62 0.07
19 INT339108 Binding of ESR1 and JUP 1 0.38 0.62 0.07
20 INT349914 Binding of Cdh1 and Jup 1 0.11 0.47 0.07
21 INT295122 Bmp2 Regulation of Grxcr1 1 0.02 0.66 0.06
22 INT234968 IgG Negative_regulation of Jup 1 0.02 1.09 0.06
23 INT295120 Bmp2 Regulation of Transcription of Pou1f1 1 0.24 0.66 0.06
24 INT181814 Gsk3b Regulation of Gata4 1 0.06 0.37 0.05
25 INT173613 BMP2 Positive_regulation of INCENP 1 0.00 0.28 0.03
26 INT287233 PDLIM7 Positive_regulation of Gene_expression of BMP2 1 0.07 0.12 0.03
27 INT192044 Binding of DSP and Jup 2 0.24 2.39 0
28 INT234995 Binding of CDH16 and Jup 1 0.00 0.27 0
29 INT274435 Binding of Zfpm2 and Mir130a 1 0.30 0.26 0
30 INT343999 INCENP Positive_regulation of BMP2 1 0.01 0 0
31 INT278021 BMP2 Positive_regulation of Gene_expression of RUNX1T1 1 0.02 0.5 0
32 INT314693 Binding of TBX2 and TBX5 1 0.16 0.84 0
33 INT234969 Jup Regulation of Gene_expression of Dsp 1 0.01 0.54 0
34 INT205451 Binding of BMP2 and Acvr2a 1 0.02 0.05 0
35 INT235007 Binding of DSG1 and Jup 1 0.08 0.36 0
36 INT235005 Positive_regulation of Binding of DSG1 and Jup 1 0.08 0.36 0
37 INT234983 IgG Positive_regulation of Protein_catabolism of Jup 1 0.03 0.61 0
38 INT274432 Mir130a Regulation of Zfpm2 1 0.22 0.08 0
39 INT192045 Jup Positive_regulation of RYR2 1 0.11 0.29 0
40 INT274431 Mir130a Regulation of Gene_expression of Zfpm2 1 0.50 0.79 0
41 INT196023 Bmp2 Negative_regulation of Gene_expression of Bmp4 1 0.09 0.07 0
42 INT205410 Binding of BMP2 and BMPR2 1 0.07 0.05 0
43 INT234970 Binding of Jup and Lat 1 0.01 0 0
44 INT344001 INCENP Positive_regulation of Gene_expression of BMP2 1 0.01 0 0
45 INT274434 Binding of Gata4 and Zfpm2 1 0.12 0.56 0
46 INT196021 Bmp2 Positive_regulation of Gene_expression of Bmp4 1 0.09 0.08 0
47 INT266555 Mapk8 Regulation of JUP 1 0.08 0.1 0
48 INT295129 Proc Regulation of Bmp2 1 0.00 0.48 0
49 INT234987 Binding of Jup and Dsp 1 0.01 0.18 0
50 INT274433 Binding of Zfpm2 and Uts2r 1 0.08 0.17 0
51 INT274436 Mir130a Regulation of Transcription of Zfpm2 1 0.22 0 0
52 INT321594 Bmp2 Regulation of Gene_expression of Lxn 1 0.42 1.71 0
53 INT192042 Binding of Jup and Ryr2 1 0.17 1.09 0
54 INT234982 Binding of Jup and Pkp1 1 0.00 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for atrioventricular valve morphogenesis. They are ordered first by their pain relevance and then by number of times they were reported in atrioventricular valve morphogenesis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT85809 Gene_expression of BMP2 46 0.78 9.91 3.05
2 INT96423 Gene_expression of Bmp2 61 0.78 25.07 3.01
3 INT89871 Gene_expression of Gata4 11 0.69 1.05 1.53
4 INT130014 Positive_regulation of BMP2 11 0.66 5.34 1.42
5 INT70619 Regulation of Bmp2 6 0.60 3.1 1.29
6 INT96424 Transcription of Bmp2 6 0.69 6.34 1.11
7 INT160538 Binding of Bmp2 4 0.40 2.08 1.07
8 INT242171 Protein_catabolism of JUP 4 0.96 0.91 1.01
9 INT109069 Transcription of Gata4 4 0.64 0.52 1.01
10 INT109070 Positive_regulation of Transcription of Gata4 1 0.03 0 1.01
11 INT114664 Binding of BMP2 12 0.37 6.54 0.91
12 INT89867 Negative_regulation of Gene_expression of Gata4 3 0.38 0.17 0.61
13 INT238049 Positive_regulation of Gene_expression of BMP2 8 0.51 2.06 0.59
14 INT89868 Negative_regulation of Gata4 1 0.38 0 0.57
15 INT85808 Localization of BMP2 7 0.77 1.94 0.51
16 INT266535 Phosphorylation of JUP 3 0.79 0.63 0.49
17 INT145301 Regulation of Gene_expression of Bmp2 1 0.32 1.16 0.48
18 INT242168 Transcription of JUP 4 0.67 1.17 0.46
19 INT120086 Gene_expression of Bmp2 5 0.27 2.34 0.43
20 INT84945 Transcription of BMP2 5 0.61 1.8 0.36
21 INT196026 Positive_regulation of Gene_expression of Bmp2 14 0.69 3.19 0.35
22 INT242169 Positive_regulation of Protein_catabolism of JUP 1 0.49 0.23 0.34
23 INT109058 Positive_regulation of Gene_expression of Gata4 2 0.29 0 0.33
24 INT185886 Gene_expression of JUP 20 0.75 15.41 0.32
25 INT221860 Negative_regulation of Jup 9 0.15 6.82 0.26
26 INT145305 Positive_regulation of Bmp2 12 0.69 8.65 0.24
27 INT109699 Regulation of BMP2 5 0.43 2.21 0.23
28 INT234903 Gene_expression of Jup 1 0.23 7.1 0.2
29 INT148064 Localization of Bmp2 2 0.29 0.14 0.17
30 INT106010 Positive_regulation of Bmp2 2 0.26 0.91 0.15
31 INT205083 Positive_regulation of JUP 6 0.49 5.51 0.13
32 INT254992 Negative_regulation of Gene_expression of BMP2 3 0.34 0.56 0.11
33 INT238044 Positive_regulation of Transcription of BMP2 2 0.43 0.83 0.11
34 INT326976 Regulation of Localization of BMP2 1 0.59 0.08 0.1
35 INT196035 Localization of Bmp2 3 0.63 0.23 0.09
36 INT278036 Negative_regulation of BMP2 2 0.34 0.64 0.09
37 INT242173 Positive_regulation of Gene_expression of JUP 2 0.49 2.37 0.09
38 INT114663 Regulation of Binding of BMP2 1 0.38 0.19 0.09
39 INT309877 Localization of JUP 2 0.73 1.38 0.08
40 INT163072 Regulation of Binding of Bmp2 1 0.30 0.52 0.08
41 INT339206 Negative_regulation of Localization of JUP 1 0.41 1.1 0.08
42 INT234894 Negative_regulation of Protein_catabolism of Jup 1 0.17 2.87 0.08
43 INT234866 Regulation of Jup 2 0.08 0.58 0.06
44 INT234899 Positive_regulation of Protein_catabolism of Jup 1 0.21 0.88 0.06
45 INT329585 Regulation of Negative_regulation of Jup 1 0.01 0.23 0.06
46 INT234931 Protein_catabolism of Jup 1 0.29 2.23 0.06
47 INT234915 Positive_regulation of Gene_expression of Jup 1 0.15 2.7 0.06
48 INT196025 Negative_regulation of Bmp2 2 0.34 0.14 0.05
49 INT229753 Positive_regulation of Gene_expression of Bmp2 2 0.11 1.22 0.04
50 INT287236 Positive_regulation of Positive_regulation of BMP2 1 0.29 0.08 0.04
51 INT248540 Positive_regulation of Gata4 2 0.23 0.95 0.03
52 INT234890 Phosphorylation of Jup 1 0.24 1.56 0.03
53 INT234867 Localization of Jup 1 0.24 2.84 0.03
54 INT262960 Gene_expression of TBX5 1 0.23 0.09 0.03
55 INT266537 Positive_regulation of Phosphorylation of JUP 2 0.49 0.29 0
56 INT189593 Regulation of Gene_expression of BMP2 2 0.33 0.8 0
57 INT274404 Binding of Gata4 2 0.16 0.89 0
58 INT266534 Negative_regulation of Phosphorylation of JUP 2 0.41 0.15 0
59 INT242174 Negative_regulation of Gene_expression of JUP 2 0.41 2.58 0
60 INT221864 Binding of JUP 2 0.36 1.05 0
61 INT145300 Positive_regulation of Positive_regulation of Bmp2 2 0.34 1.03 0
62 INT221859 Binding of Jup 2 0.14 2.21 0
63 INT196031 Binding of Bmp2 1 0.16 0 0
64 INT274420 Positive_regulation of Gene_expression of Zfpm2 1 0.49 0.51 0
65 INT309874 Positive_regulation of Binding of JUP 1 0.49 0.32 0
66 INT278735 Negative_regulation of Gene_expression of Bmp2 1 0.43 0.06 0
67 INT274412 Transcription of Zfpm2 1 0.53 0 0
68 INT274418 Regulation of Gene_expression of Zfpm2 1 0.45 1.42 0
69 INT274417 Negative_regulation of Zfpm2 1 0.43 6.99 0
70 INT274428 Regulation of Binding of Zfpm2 1 0.45 0.15 0
71 INT234877 Positive_regulation of Binding of Jup 1 0.21 0.24 0
72 INT242170 Negative_regulation of JUP 1 0.42 0.85 0
73 INT274405 Gene_expression of Zfpm2 1 0.77 6.51 0
74 INT274425 Negative_regulation of Gene_expression of Zfpm2 1 0.42 0.06 0
75 INT278737 Positive_regulation of Transcription of Bmp2 1 0.47 1.4 0
76 INT120087 Negative_regulation of Gene_expression of Bmp2 1 0.11 0.14 0
77 INT274411 Positive_regulation of Zfpm2 1 0.46 0.53 0
78 INT309876 Regulation of JUP 1 0.60 0.67 0
79 INT234918 Positive_regulation of Jup 1 0.15 1.08 0
80 INT274414 Regulation of Zfpm2 1 0.61 0.59 0
81 INT181811 Localization of Gata4 1 0.54 0.3 0
82 INT278040 Negative_regulation of Localization of BMP2 1 0.32 0.32 0
83 INT309875 Regulation of Gene_expression of JUP 1 0.44 0.39 0
84 INT274408 Binding of Zfpm2 1 0.37 0.77 0
85 INT234896 Negative_regulation of Gene_expression of Jup 1 0.13 0.54 0
86 INT355092 Positive_regulation of Transcription of JUP 1 0.49 0.05 0
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