GO:0003334

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Name keratinocyte development
Categary Process
Go Slim No
Go Link GO:0003334
Unique Molecular Interactions 29
Total Molecular Interactions 30
Total Single Events 209
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for keratinocyte development. They are ordered first by their pain relevance and then by number of times they were reported for keratinocyte development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT207540 Tfap2a Regulation of Oprm1 1 0.13 0.06 0.7
2 INT135207 Gmeb1 Regulation of Gene_expression of Tfap2a 1 0.07 0.48 0.69
3 INT135206 Ighen Regulation of Gene_expression of Tfap2a 1 0.06 0.48 0.69
4 INT135202 Tfap2a Regulation of Gene_expression of Ighen 1 0.06 0.48 0.69
5 INT135213 Tfap2a Regulation of Gene_expression of Nfkb1 1 0.02 0.48 0.69
6 INT135211 Nfkb1 Regulation of Gene_expression of Tfap2a 1 0.02 0.48 0.69
7 INT135204 Tfap2a Regulation of Gene_expression of Gmeb1 1 0.10 0.48 0.69
8 INT207543 Tfap2a Regulation of Qsox1 1 0.04 0.06 0.67
9 INT97949 Negative_regulation of NRP2 Negative_regulation of Positive_regulation of CDC42 1 0.06 0.72 0.51
10 INT97953 ST3GAL3 Positive_regulation of CDC42 1 0.09 0.7 0.5
11 INT244028 Positive_regulation of Binding of Cacnb3 and Tfap2a 1 0.01 0.24 0.49
12 INT244037 Positive_regulation of Binding of Prkaca and Tfap2a 1 0.01 0.24 0.49
13 INT244000 Positive_regulation of Binding of Tfap2a and Dnm1 1 0.04 0.24 0.49
14 INT244035 Binding of Prkaca and Tfap2a 1 0.01 0.24 0.49
15 INT243997 Binding of Tfap2a and Dnm1 1 0.03 0.24 0.49
16 INT244060 Binding of Cacnb3 and Tfap2a 1 0.00 0.24 0.49
17 INT301054 Tfap2a Regulation of Gene_expression of Faslg 1 0.00 1.23 0.34
18 INT285567 Binding of IL1B and Cdc42 1 0.03 0.77 0.31
19 INT292565 MAP3K5 Positive_regulation of Positive_regulation of CDC42 1 0.02 0 0.23
20 INT287267 EGF Positive_regulation of CDC42 1 0.12 0.16 0.11
21 INT181083 Binding of Akt1 and Cdc42 1 0.00 0.79 0.03
22 INT234996 Ctnnd1 Positive_regulation of CDC42 1 0.01 0.07 0
23 INT245820 Binding of Sp1 and Tfap2a 1 0.03 0.64 0
24 INT267257 BCL11B Regulation of Transcription of BMI1 1 0.28 0.74 0
25 INT267258 Binding of TP53 and BCL11B 1 0.09 0.42 0
26 INT249149 Binding of Cdc42 and Was 1 0.08 0.18 0
27 INT245828 Binding of VEGFA and Tfap2a 1 0.01 0.64 0
28 INT267259 BCL11B Regulation of BMI1 1 0.65 1.48 0
29 INT181085 Binding of Cdc42 and Errfi1 1 0.08 0.67 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for keratinocyte development. They are ordered first by their pain relevance and then by number of times they were reported in keratinocyte development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT207521 Gene_expression of Tfap2a 7 0.48 1.89 1.45
2 INT97955 Positive_regulation of CDC42 8 0.49 2.47 1.19
3 INT84511 Positive_regulation of Tfap2a 3 0.27 0.72 1.04
4 INT243974 Binding of Tfap2a 7 0.18 1.36 0.93
5 INT161682 Positive_regulation of Cdc42 8 0.53 4.55 0.9
6 INT221796 Positive_regulation of Gene_expression of Tfap2a 2 0.10 1.19 0.83
7 INT207535 Transcription of Tfap2a 3 0.31 0.98 0.74
8 INT135197 Gene_expression of Tfap2a 1 0.45 0.48 0.69
9 INT180107 Regulation of Cdc42 3 0.16 0.18 0.6
10 INT207529 Localization of Tfap2a 2 0.34 0.13 0.6
11 INT243970 Phosphorylation of Tfap2a 2 0.25 0.56 0.56
12 INT267269 Gene_expression of BCL11B 62 0.78 48.75 0.55
13 INT97956 Negative_regulation of CDC42 3 0.27 1.58 0.55
14 INT183881 Localization of CDC42 3 0.49 1.92 0.23
15 INT183876 Regulation of CDC42 3 0.30 1.94 0.19
16 INT162939 Binding of Tfap2a 1 0.26 0.34 0.17
17 INT162940 Negative_regulation of Tfap2a 1 0.32 0.34 0.17
18 INT162941 Negative_regulation of Binding of Tfap2a 1 0.32 0.34 0.17
19 INT197290 Gene_expression of Cdc42 9 0.35 2.52 0.15
20 INT206133 Binding of CDC42 3 0.25 0.8 0.12
21 INT149063 Regulation of BCL11B 1 0.11 0.06 0.12
22 INT197282 Positive_regulation of Gene_expression of Cdc42 3 0.26 0.12 0.08
23 INT206169 Gene_expression of CDC42 2 0.26 1.05 0.05
24 INT206167 Positive_regulation of Gene_expression of CDC42 1 0.08 0.05 0.05
25 INT254795 Negative_regulation of Cdc42 2 0.12 1.53 0
26 INT267282 Negative_regulation of BCL11B 1 0.38 1.19 0
27 INT267268 Positive_regulation of BCL11B 1 0.70 6.43 0
28 INT270614 Localization of Cdc42 1 0.55 0.95 0
29 INT267280 Transcription of BCL11B 1 0.69 1.37 0
30 INT197294 Regulation of Gene_expression of Cdc42 1 0.13 0 0
31 INT267278 Negative_regulation of Gene_expression of BCL11B 1 0.51 2.67 0
32 INT267281 Localization of BCL11B 1 0.75 3.21 0
33 INT267275 Regulation of Transcription of BCL11B 1 0.45 0.64 0
34 INT282269 Binding of Cdc42 1 0.08 0.33 0
35 INT287281 Positive_regulation of Positive_regulation of CDC42 1 0.26 0 0
36 INT267279 Positive_regulation of Gene_expression of BCL11B 1 0.70 14.02 0
37 INT282272 Positive_regulation of Binding of Cdc42 1 0.11 0.33 0
38 INT267283 Regulation of Gene_expression of BCL11B 1 0.45 0.67 0
39 INT267277 Binding of BCL11B 1 0.37 0.96 0
40 INT267273 Negative_regulation of Positive_regulation of BCL11B 1 0.43 1.38 0
41 INT311630 Negative_regulation of Tfap2a 1 0.34 0.23 0
42 INT319128 Positive_regulation of Binding of Tfap2a 1 0.23 0.5 0
43 INT311626 Negative_regulation of Gene_expression of Tfap2a 1 0.34 0.29 0
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