GO:0003406

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Name retinal pigment epithelium development
Categary Process
Go Slim No
Go Link GO:0003406
Unique Molecular Interactions 37
Total Molecular Interactions 52
Total Single Events 129
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for retinal pigment epithelium development. They are ordered first by their pain relevance and then by number of times they were reported for retinal pigment epithelium development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT140985 Gli3 Regulation of Ihh 1 0.29 0.85 0.85
2 INT149899 Ihh Positive_regulation of Mmp7 1 0.04 1.69 0.65
3 INT149894 Ihh Positive_regulation of Localization of Mmp14 1 0.04 2.06 0.47
4 INT113040 IHH Regulation of Gene_expression of INS 1 0.12 0.37 0.37
5 INT149897 Ihh Positive_regulation of Mmp14 1 0.03 0.93 0.33
6 INT149896 Ihh Regulation of Gene_expression of Col1a1 1 0.06 0.89 0.33
7 INT149895 Ihh Regulation of Localization of Mmp7 1 0.03 0.98 0.33
8 INT149902 Ihh Positive_regulation of SGCG 1 0.45 0.76 0.32
9 INT309366 Pax2 Negative_regulation of Transcription of Slc6a5 1 0.03 0 0.31
10 INT309369 Ptf1a Positive_regulation of Pax2 1 0.10 0 0.3
11 INT149898 Ihh Regulation of Localization of Mmp14 1 0.03 1.29 0.27
12 INT210798 Ihh Positive_regulation of Itgbl1 1 0.34 0 0.23
13 INT210795 Ihh Negative_regulation of Itgb1 1 0.30 0 0.17
14 INT210782 Ihh Negative_regulation of Itgbl1 1 0.31 0 0.16
15 INT210804 Ihh Negative_regulation of Timp4 1 0.32 0 0.16
16 INT156833 Binding of MED1 and TRPV6 1 0.32 0 0.15
17 INT156837 Binding of CYP24A1 and MED1 1 0.47 0 0.15
18 INT309371 Lhx1 Positive_regulation of Gene_expression of Pax2 1 0.08 0.07 0.11
19 INT309372 Lhx5 Positive_regulation of Gene_expression of Pax2 1 0.09 0.07 0.11
20 INT165161 Ihh Positive_regulation of Sostdc1 1 0.58 0.07 0.09
21 INT165160 Regulation of Ihh Positive_regulation of Sostdc1 1 0.23 0.07 0.09
22 INT165158 Positive_regulation of Ihh Positive_regulation of Sostdc1 1 0.42 0.07 0.09
23 INT210788 Ihh Negative_regulation of Coro1a 1 0.02 0 0.08
24 INT210790 Ihh Negative_regulation of Cdkn1c 1 0.30 0 0.08
25 INT210787 Ihh Negative_regulation of Nr3c1 1 0.33 0 0.08
26 INT225490 Med1 Positive_regulation of Ppara 1 0.12 0.26 0.06
27 INT261393 Binding of Nsdhl and Med1 1 0.02 1 0.04
28 INT225585 Regulation of Binding of Med1 and Tpr 1 0.00 0.07 0
29 INT244839 Lbx1 Positive_regulation of Pax2 1 0.39 0 0
30 INT177262 Binding of MED1 and SV2A 1 0.23 0 0
31 INT197794 Negative_regulation of Pthlh Regulation of Ihh 1 0.36 1.33 0
32 INT225481 Binding of Med1 and Acp5 1 0.16 0 0
33 INT177286 Binding of CXADR and MED1 1 0.27 0 0
34 INT297691 Binding of Fut1 and Pax2 1 0.03 0 0
35 INT225541 Binding of Med1 and Tpr 1 0.00 0.07 0
36 INT177280 Binding of MED1 and FAUP1 1 0.01 0 0
37 INT197793 Pthlh Regulation of Ihh 1 0.22 1.32 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for retinal pigment epithelium development. They are ordered first by their pain relevance and then by number of times they were reported in retinal pigment epithelium development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT113041 Gene_expression of IHH 9 0.78 5.83 2.87
2 INT140983 Gene_expression of Ihh 7 0.78 2.06 1.15
3 INT113042 Localization of IHH 1 0.70 0.77 0.61
4 INT140984 Regulation of Ihh 5 0.54 2.81 0.56
5 INT145045 Gene_expression of Med1 29 0.65 5.37 0.39
6 INT233917 Gene_expression of MED1 2 0.20 0.17 0.38
7 INT213507 Gene_expression of Pax2 10 0.67 1.41 0.34
8 INT166716 Negative_regulation of Ihh 3 0.43 0.67 0.33
9 INT309354 Regulation of Pax2 1 0.10 0 0.29
10 INT106734 Phosphorylation of MED1 4 0.74 1.65 0.28
11 INT309339 Negative_regulation of Localization of Pax2 1 0.15 0 0.28
12 INT149893 Positive_regulation of Gene_expression of Ihh 1 0.69 0.62 0.26
13 INT149892 Gene_expression of Ihh 1 0.77 0.61 0.26
14 INT149888 Localization of Ihh 1 0.75 0.77 0.2
15 INT106730 Regulation of Phosphorylation of MED1 2 0.24 0.7 0.16
16 INT278241 Regulation of IHH 2 0.31 1.16 0.14
17 INT309352 Localization of Pax2 1 0.27 0 0.14
18 INT106731 Negative_regulation of Phosphorylation of MED1 1 0.02 0.96 0.12
19 INT210805 Negative_regulation of IHH 2 0.42 0.74 0.08
20 INT156864 Positive_regulation of Phosphorylation of MED1 1 0.45 0 0.07
21 INT168919 Regulation of Regulation of Ihh 1 0.40 0.43 0.07
22 INT244741 Positive_regulation of Gene_expression of Pax2 1 0.38 0 0.06
23 INT251811 Positive_regulation of IHH 1 0.29 0.09 0.05
24 INT165149 Positive_regulation of Ihh 1 0.42 0.09 0.04
25 INT294470 Transcription of IHH 1 0.16 0.28 0.03
26 INT307189 Localization of Med1 3 0.53 0.32 0
27 INT225400 Positive_regulation of Gene_expression of Med1 2 0.35 0.82 0
28 INT225358 Negative_regulation of Gene_expression of Med1 2 0.30 1.16 0
29 INT177336 Positive_regulation of Binding of MED1 1 0.24 0 0
30 INT307197 Negative_regulation of Med1 1 0.30 0.7 0
31 INT244782 Negative_regulation of Pax2 1 0.44 0 0
32 INT307188 Transcription of Med1 1 0.48 0.7 0
33 INT322888 Negative_regulation of Ihh 1 0.26 0.45 0
34 INT225389 Regulation of Binding of Med1 1 0.17 0.07 0
35 INT177320 Binding of MED1 1 0.25 0 0
36 INT225457 Binding of Med1 1 0.35 0.28 0
37 INT341851 Positive_regulation of MED1 1 0.01 0.5 0
38 INT334482 Regulation of Gene_expression of Med1 1 0.17 0.1 0
39 INT213529 Negative_regulation of Gene_expression of Pax2 1 0.37 0.23 0
40 INT334481 Negative_regulation of Localization of Med1 1 0.16 0.09 0
41 INT301356 Binding of Ihh 1 0.08 0.06 0
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