GO:0003674

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Name molecular_function
Categary Function
Go Slim Yes
Go Link GO:0003674
Unique Molecular Interactions 1947
Total Molecular Interactions 2704
Total Single Events 21587
Pain Genes Associated 454

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for molecular_function. They are ordered first by their pain relevance and then by number of times they were reported for molecular_function. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT6078 Pomc Positive_regulation of Localization of Penk 13 0.51 0 15.49
2 INT2161 Gnrh1 Positive_regulation of Localization of LH 33 0.73 0.87 14.34
3 INT69886 Ngf Positive_regulation of Calca 8 0.76 2.98 12.77
4 INT145775 Ngf Positive_regulation of Trpv1 11 0.72 7.71 11.25
5 INT6079 Pomc Positive_regulation of Penk 9 0.43 0 9.46
6 INT2714 Pomc Positive_regulation of Localization of Prl 17 0.79 0.5 8.18
7 INT69229 Ngf Positive_regulation of Gene_expression of Bdnf 6 0.76 8.19 6.66
8 INT122779 Ngf Positive_regulation of Gene_expression of Trpv1 8 0.74 4.31 6.1
9 INT140935 Binding of Cd40lg and Cd40 1 0.30 6.34 5.61
10 INT15842 Crh Positive_regulation of Localization of Pomc 15 0.73 5 5.05
11 INT1310 Pomc Regulation of Localization of Prl 9 0.40 0.61 4.96
12 INT69888 Ngf Positive_regulation of Localization of Calca 4 0.52 0.51 4.95
13 INT14095 Binding of Vsig2 and Coq10a 2 0.33 1.98 4.55
14 INT240653 Ngf Positive_regulation of Positive_regulation of Bdnf 1 0.55 2.97 4.23
15 INT1313 Pomc Positive_regulation of Prl 7 0.35 0 4.19
16 INT20456 Binding of Pomc and Penk 9 0.41 0.26 3.93
17 INT82023 Binding of Ntrk1 and Ngf 5 0.53 3.48 3.92
18 INT122349 Ngf Regulation of Trpv1 3 0.64 1.55 3.79
19 INT180813 Ngf Positive_regulation of Sorbs1 1 0.04 2.09 3.79
20 INT141254 Ngf Regulation of Transcription of Trpv1 1 0.53 1.37 3.74
21 INT85541 Ngf Positive_regulation of Gene_expression of Calca 2 0.55 1.84 3.71
22 INT132862 Ngf Positive_regulation of Bdnf 4 0.46 4.05 3.65
23 INT29837 Gnrh1 Positive_regulation of LH 6 0.67 0 3.53
24 INT155891 Nps Negative_regulation of Positive_regulation of Casp3 1 0.27 0.17 3.48
25 INT74159 Ngf Regulation of Gene_expression of Calca 2 0.60 1.66 3.22
26 INT7193 Abl2 Positive_regulation of Ctsb 1 0.21 0 3.21
27 INT6076 Negative_regulation of Pomc Positive_regulation of Penk 3 0.31 0 3.14
28 INT122780 Ngf Regulation of Gene_expression of Trpv1 4 0.65 3.74 3.11
29 INT221746 Ngf Positive_regulation of Ntrk1 1 0.02 0.92 2.88
30 INT127621 Bst1 Regulation of Positive_regulation of Fos 1 0.26 0 2.73
31 INT326585 Binding of GYPA and SLC6A3 1 0.13 0.86 2.64
32 INT152113 Binding of NTSR1 and Ngf 3 0.33 2.09 2.62
33 INT30345 Pomc Regulation of Localization of Penk 3 0.31 0 2.61
34 INT170037 Ngf Regulation of Gene_expression of DRGX 1 0.01 1.37 2.46
35 INT103330 Ngf Positive_regulation of Gdnf 2 0.28 1.27 2.45
36 INT103332 Ngf Regulation of Gene_expression of TRPV1 3 0.09 2.6 2.4
37 INT29716 Crh Negative_regulation of Localization of Gnrh1 5 0.44 0 2.35
38 INT121726 Ngf Positive_regulation of Phosphorylation of Akt1 1 0.37 1.4 2.34
39 INT108987 Ngf Regulation of Gene_expression of Sit1 1 0.00 1.46 2.32
40 INT85252 Negative_regulation of Chi3l1 Positive_regulation of Casp3 1 0.01 0 2.26
41 INT85251 Chi3l1 Positive_regulation of Casp3 1 0.01 0 2.25
42 INT91860 Npy Regulation of Npy1r 2 0.28 1.13 2.24
43 INT40408 Positive_regulation of Gnrh1 Positive_regulation of LH 2 0.58 0 2.21
44 INT69887 Ngf Regulation of Calca 2 0.49 0.1 2.19
45 INT334136 Binding of IFNA1 and Acsm3 1 0.01 4.52 2.19
46 INT113451 Ngf Regulation of Gene_expression of ASIC3 1 0.07 1.35 2.18
47 INT12140 Ngf Regulation of Chat 1 0.44 1.67 2.18
48 INT1315 Pomc Positive_regulation of Localization of Gnrhr 3 0.38 0.16 2.16
49 INT250867 Fgf8 Positive_regulation of Protein_catabolism of Ecm1 1 0.06 4.35 2.14
50 INT120319 Ghrh Regulation of Ngf 1 0.25 1.89 2.11
51 INT79470 Mgat4a Regulation of Localization of Calca 1 0.08 1.72 2.1
52 INT113452 Ngf Positive_regulation of Gene_expression of ASIC3 1 0.19 1.34 2.08
53 INT28387 Pomc Positive_regulation of Localization of LH 2 0.40 0.28 2.07
54 INT331105 Vmn1r71 Negative_regulation of Mc1r 1 0.04 0.64 2.07
55 INT138962 Dbi Positive_regulation of Pomc 1 0.00 1.53 2
56 INT26948 Pomc Positive_regulation of Localization of Gh1 2 0.22 0.15 1.99
57 INT34662 Abat Positive_regulation of Localization of Gnrh1 1 0.26 0 1.98
58 INT189999 Binding of Vta1 and Cfp 2 0.08 1.25 1.97
59 INT116815 Binding of Pias1 and Ppbp 1 0.36 0.86 1.92
60 INT31438 Penk Positive_regulation of Localization of Pomc 1 0.18 0 1.9
61 INT75069 Penk Regulation of Gene_expression of Pkhd1l1 1 0.09 0 1.85
62 INT276668 Ngf Regulation of Nav1 1 0.09 0.98 1.85
63 INT9786 Gnrh1 Regulation of LH 7 0.40 0.58 1.82
64 INT99138 Coq10a Regulation of Insrr 1 0.01 0.73 1.81
65 INT204552 Sult2a2 Regulation of Cia1 1 0.01 2.75 1.75
66 INT26676 Pomc Regulation of Localization of Trh 3 0.14 0 1.73
67 INT27788 Gnrh1 Positive_regulation of Positive_regulation of LH 3 0.55 0.17 1.72
68 INT45306 Pomc Positive_regulation of ENG 2 0.07 1.11 1.68
69 INT80199 Ngf Regulation of Transcription of Rab38 1 0.01 1.48 1.68
70 INT108066 Binding of NTRK1 and Ngf 3 0.33 2.56 1.66
71 INT278223 Binding of NOS3 and ACSM3 1 0.41 6.32 1.65
72 INT172047 Binding of HLA-A and LRRC23 1 0.22 3.32 1.64
73 INT32412 Penk Regulation of Pomc 3 0.21 0.36 1.62
74 INT94270 Pomc Regulation of Transcription of Crh 1 0.17 0.67 1.6
75 INT140341 Ngf Positive_regulation of Gene_expression of Oprm1 1 0.02 0.33 1.59
76 INT48790 Negative_regulation of Rtcd1 Negative_regulation of Pax3 1 0.02 0 1.59
77 INT41652 Binding of Pomc and Oprl1 3 0.16 0 1.57
78 INT94271 Pomc Regulation of Avp 1 0.20 0.67 1.57
79 INT170654 Binding of Ntf3 and Ngf 1 0.38 1.66 1.54
80 INT209087 Crh Positive_regulation of Ceacam3 1 0.24 1.45 1.54
81 INT140017 Avp Positive_regulation of Gene_expression of Pomc 1 0.38 0.85 1.52
82 INT63490 Negative_regulation of Dio1 Positive_regulation of Rtcd1 1 0.01 0.58 1.51
83 INT140008 Avp Positive_regulation of Pomc 1 0.38 0.84 1.51
84 INT63489 Dio1 Positive_regulation of Rtcd1 1 0.01 0.58 1.51
85 INT166360 Negative_regulation of Crhr1 Negative_regulation of Positive_regulation of Pomc 1 0.02 0.36 1.5
86 INT334131 Acsm3 Positive_regulation of Mip 1 0.13 3.12 1.48
87 INT165450 Gal Regulation of Ceacam3 1 0.41 0.06 1.47
88 INT144452 Binding of GPM6A and GPM6B 1 0.28 0 1.46
89 INT1314 Pomc Regulation of Localization of Gnrhr 2 0.16 0.14 1.45
90 INT21425 Binding of Pomc and Gtpbp4 1 0.01 0.1 1.45
91 INT131039 Binding of Oprm1 and Prf1 1 0.17 0 1.45
92 INT131041 Negative_regulation of Binding of Oprm1 and Prf1 1 0.21 0 1.45
93 INT131040 Binding of Oprm1 and S100a9 1 0.24 0 1.45
94 INT180789 Ngf Regulation of Localization of Trpv1 1 0.28 1.22 1.44
95 INT69337 Oprm1 Positive_regulation of Atxn2l 1 0.01 0.27 1.43
96 INT28992 Tmpo Positive_regulation of Pomc 1 0.36 3.18 1.41
97 INT68723 Pomgnt1 Negative_regulation of Gene_expression of Fos 1 0.12 0 1.41
98 INT180809 Ngf Positive_regulation of Positive_regulation of Sorbs1 1 0.03 0.84 1.4
99 INT180808 Ngf Positive_regulation of Gene_expression of Sorbs1 1 0.03 0.84 1.4
100 INT154685 Syt17 Positive_regulation of Trpa1 1 0.32 0.71 1.4
101 INT27123 Binding of Pomc and Cck 2 0.31 0 1.38
102 INT158762 Binding of Vwf and Mthfr 1 0.05 1.85 1.37
103 INT82025 Negative_regulation of Binding of Ntrk1 and Ngf 1 0.47 0.64 1.37
104 INT66569 Pomc Positive_regulation of Atxn2l 1 0.03 0 1.36
105 INT115272 Neu1 Positive_regulation of Coq10a 1 0.43 0.41 1.35
106 INT115271 Neu1 Positive_regulation of Coq10a 1 0.01 0.41 1.35
107 INT60992 Ngf Regulation of CRTAC1 1 0.00 0 1.35
108 INT151770 Binding of P2RX3 and Ngf 1 0.18 0.9 1.35
109 INT140531 Ngf Positive_regulation of DYT10 1 0.72 1.83 1.34
110 INT298455 Calca Positive_regulation of Gene_expression of Ceacam3 1 0.17 0.47 1.34
111 INT60989 Ngf Regulation of Th 1 0.17 0 1.34
112 INT145473 Mastl Positive_regulation of Dnahc8 1 0.07 0.06 1.33
113 INT180786 Calca Regulation of Positive_regulation of Ngf 1 0.40 0 1.32
114 INT71395 Ugt2a2 Regulation of Bcl2a1a 1 0.00 0.1 1.32
115 INT132412 Negative_regulation of Ngf Negative_regulation of Ptgs1 1 0.01 0.81 1.31
116 INT27425 Mtr Positive_regulation of Gene_expression of Il1f5 1 0.06 0 1.3
117 INT138211 Mzb1 Regulation of Sst 1 0.05 0.41 1.29
118 INT138212 Mzb1 Regulation of Localization of Sst 1 0.12 0.41 1.29
119 INT57263 Binding of Oprd1 and Atxn2l 1 0.02 0 1.29
120 INT18659 Plat Regulation of ZC3H12D 1 0.02 0.1 1.29
121 INT138213 Mzb1 Regulation of Localization of Tac1 1 0.01 0.41 1.29
122 INT138210 Mzb1 Regulation of Calca 1 0.25 0.41 1.29
123 INT31008 Crh Positive_regulation of Pomc 3 0.49 2.31 1.28
124 INT161995 Binding of Ctu2 and Fbxo23 1 0.06 0.33 1.28
125 INT138214 Mzb1 Regulation of Tac1 1 0.01 0.41 1.28
126 INT125950 Syt17 Regulation of Trpv1 1 0.11 0.43 1.28
127 INT5518 Pomc Negative_regulation of Crh 2 0.36 0.42 1.26
128 INT271602 Binding of Pdgfa and Pdgfrl 1 0.02 0.86 1.25
129 INT236835 Binding of CISH and CSF2 1 0.06 1.43 1.25
130 INT104348 Pnoc Negative_regulation of Localization of Gnrh1 1 0.45 0 1.24
131 INT34471 Negative_regulation of Pomc Regulation of Slc3a1 1 0.05 0.12 1.24
132 INT21858 Maoa Regulation of Gene_expression of Spna1 1 0.12 0.18 1.24
133 INT50385 Bdnf Positive_regulation of Pomc 1 0.22 0.47 1.23
134 INT21859 Maoa Regulation of Spna1 1 0.12 0.18 1.23
135 INT34473 Pomc Regulation of Slc3a1 1 0.03 0.07 1.23
136 INT334129 Acsm3 Positive_regulation of Gene_expression of Icam1 1 0.22 2.89 1.22
137 INT121729 Negative_regulation of Ngf Positive_regulation of Ephb1 1 0.24 0.69 1.22
138 INT52955 Binding of Slc6a3 and Pdpn 1 0.17 1.11 1.22
139 INT56881 Ppbp Regulation of Vip 1 0.00 0 1.22
140 INT79471 Mgat4a Regulation of Calca 1 0.06 1.09 1.21
141 INT121724 Ngf Positive_regulation of Ephb1 1 0.40 0.68 1.21
142 INT82754 Cck Positive_regulation of Positive_regulation of Pomc 1 0.39 0.3 1.21
143 INT108065 Negative_regulation of Binding of Ngf and IgG-2a 1 0.01 2.38 1.2
144 INT108067 Negative_regulation of Binding of NTRK1 and Ngf 1 0.06 2.38 1.2
145 INT162419 Binding of Abpa and Cftr 1 0.04 1.66 1.19
146 INT70288 Negative_regulation of Atxn2l Positive_regulation of Racgap1 1 0.02 0.3 1.19
147 INT108064 Binding of Ngf and IgG-2a 1 0.01 2.36 1.19
148 INT57824 Binding of Trim13 and Slc25a2 1 0.01 0.08 1.19
149 INT122370 Positive_regulation of Tacr1 Positive_regulation of Ngf 1 0.30 0.17 1.18
150 INT170655 Binding of Csf2 and Ngf 1 0.36 1.25 1.18
151 INT264333 IL-17 Positive_regulation of Gene_expression of Mmp1a 1 0.05 2.88 1.18
152 INT34661 Abat Positive_regulation of Localization of Pomc 1 0.04 0 1.18
153 INT148437 Binding of Bdnf and Ngf 2 0.32 1.9 1.17
154 INT57822 Binding of Slc25a2 and Atxn2l 1 0.00 0.08 1.17
155 INT57823 Binding of Trim13 and Atxn2l 1 0.00 0.08 1.17
156 INT8308 Gnrh1 Regulation of Localization of LH 4 0.27 0 1.16
157 INT93290 Ngf Regulation of Transcription of Trpv1 1 0.02 0.34 1.16
158 INT155892 Nps Negative_regulation of Casp3 1 0.27 0.06 1.16
159 INT335435 Ngf Positive_regulation of Ltb4r 1 0.52 1.06 1.16
160 INT93289 Ngf Regulation of Trpv1 1 0.05 0.34 1.16
161 INT95045 Binding of Commd3 and Oprl1 1 0.34 0 1.16
162 INT155890 Nps Negative_regulation of Gene_expression of Casp3 1 0.27 0.05 1.15
163 INT70289 Atxn2l Positive_regulation of Racgap1 1 0.04 0.29 1.15
164 INT225104 CNR1 Positive_regulation of Gene_expression of RETNLB 1 0.01 1.41 1.14
165 INT122369 Tacr1 Positive_regulation of Ngf 1 0.30 0.16 1.14
166 INT30359 Pomc Regulation of Localization of Oxt 1 0.03 0 1.13
167 INT68164 Mthfs Positive_regulation of Positive_regulation of Alox5 1 0.00 0.64 1.13
168 INT68167 Alox5 Positive_regulation of Positive_regulation of Mthfs 1 0.00 0.64 1.13
169 INT39040 LH Positive_regulation of Localization of Gnrh1 3 0.51 0.41 1.12
170 INT68154 Mthfs Positive_regulation of Pdpk1 1 0.01 0.63 1.12
171 INT68161 Mthfs Positive_regulation of Positive_regulation of Pla2g1b 1 0.03 0.64 1.12
172 INT68155 Pla2g1b Positive_regulation of Positive_regulation of Mthfs 1 0.03 0.64 1.12
173 INT68163 Mthfs Positive_regulation of Positive_regulation of Pdpk1 1 0.01 0.64 1.12
174 INT269190 Positive_regulation of Ephb1 Positive_regulation of Ceacam3 1 0.03 0.66 1.12
175 INT121728 Ngf Positive_regulation of Phosphorylation of Pik3cb 1 0.45 0.69 1.11
176 INT56882 Binding of YY1 and Ppbp 1 0.01 0 1.11
177 INT143941 Il1f5 Negative_regulation of Gene_expression of Fos 1 0.00 1.03 1.11
178 INT209088 Binding of Ceacam3 and Crhr1 1 0.34 1.26 1.11
179 INT269200 Prkaca Positive_regulation of Phosphorylation of Ceacam3 1 0.03 0.65 1.09
180 INT155894 Nps Regulation of Gene_expression of Casp3 1 0.33 0.07 1.09
181 INT69889 Ngf Regulation of Localization of Calca 1 0.49 0.1 1.08
182 INT105690 Ngf Positive_regulation of TRPV1 1 0.05 1.43 1.08
183 INT120315 Gnrhr Negative_regulation of Positive_regulation of Ngf 1 0.11 0.85 1.07
184 INT120318 Gnrhr Negative_regulation of Ngf 1 0.11 0.85 1.07
185 INT69340 Binding of Igh-6 and Ngf 2 0.06 1.04 1.06
186 INT87320 Ngf Regulation of Gene_expression of Bdnf 2 0.38 0.97 1.06
187 INT39485 Prl Negative_regulation of Localization of Gnrh1 2 0.40 0 1.06
188 INT120317 Ghrh Regulation of Positive_regulation of Ngf 1 0.25 0.95 1.06
189 INT73311 Binding of Oprm1 and Pdpn 1 0.08 0.71 1.06
190 INT120311 Ghrh Regulation of Gene_expression of Ngf 1 0.25 0.95 1.06
191 INT93614 Ngf Positive_regulation of Ntrk1 2 0.52 0.85 1.05
192 INT82024 Binding of Ngfr and Ngf 2 0.33 1.48 1.05
193 INT57508 Pomc Negative_regulation of Adarb1 1 0.01 0.22 1.05
194 INT170653 Ngf Regulation of Csf2 1 0.34 1.11 1.05
195 INT76001 Ngf Positive_regulation of Ngfr 1 0.16 0.93 1.05
196 INT331107 Vmn1r71 Positive_regulation of Mc1r 1 0.05 0.5 1.05
197 INT7191 Negative_regulation of Abl2 Positive_regulation of Ctsb 1 0.13 0 1.04
198 INT180806 Ngf Positive_regulation of Regulation of Sorbs1 1 0.03 0.28 1.04
199 INT335401 Hgf Positive_regulation of Ngf 1 0.30 1.13 1.04
200 INT88971 Binding of Sult4a1 and Atrn 1 0.02 0.54 1.03

Single Events

The table below shows the top 100 pain related interactions that have been reported for molecular_function. They are ordered first by their pain relevance and then by number of times they were reported in molecular_function. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT439 Localization of Gnrh1 976 0.81 100.96 363.25
2 INT5680 Gene_expression of Ngf 530 0.78 264.29 310.56
3 INT886 Gene_expression of Pomc 676 0.78 129.87 295.98
4 INT11377 Positive_regulation of Ngf 331 0.70 206.5 238
5 INT1308 Localization of Pomc 457 0.81 66.83 217.5
6 INT2651 Positive_regulation of Pomc 403 0.70 95.72 206.24
7 INT1652 Regulation of Pomc 387 0.62 61.01 186.51
8 INT5513 Negative_regulation of Pomc 295 0.59 60.9 158.63
9 INT2159 Regulation of Localization of Gnrh1 200 0.62 13.28 99.07
10 INT2122 Negative_regulation of Localization of Gnrh1 226 0.59 26.92 92.04
11 INT4289 Positive_regulation of Localization of Gnrh1 202 0.70 12.3 84.01
12 INT16254 Positive_regulation of Gene_expression of Ngf 144 0.70 80.61 82.08
13 INT17546 Negative_regulation of Ngf 135 0.59 60.28 77.19
14 INT12001 Regulation of Ngf 97 0.62 54.64 76.25
15 INT3034 Localization of Ngf 126 0.81 50.81 72.84
16 INT2055 Regulation of Gnrh1 185 0.62 23.65 71.26
17 INT2123 Positive_regulation of Gnrh1 209 0.70 24.2 68.97
18 INT1603 Negative_regulation of Rtcd1 131 0.51 29.99 66.66
19 INT24989 Positive_regulation of Cfp 125 0.61 29.55 64.9
20 INT2056 Negative_regulation of Gnrh1 175 0.59 33.43 63.32
21 INT1307 Positive_regulation of Localization of Pomc 120 0.70 24.58 58.48
22 INT1463 Binding of Pomc 129 0.48 15.89 56.27
23 INT5506 Positive_regulation of Gene_expression of Pomc 132 0.70 26.78 54.3
24 INT2197 Gene_expression of Gnrh1 184 0.78 40.04 50.57
25 INT19078 Binding of Ngf 78 0.48 31.03 44.33
26 INT66867 Gene_expression of Ceacam3 58 0.67 30.44 40.7
27 INT2782 Regulation of Gene_expression of Pomc 75 0.62 15.04 38.97
28 INT65889 Gene_expression of RETNLB 73 0.34 60.98 38.3
29 INT11854 Gene_expression of Il1rl1 57 0.77 30.19 38.25
30 INT17736 Gene_expression of Cfp 111 0.65 40.68 36.61
31 INT1495 Positive_regulation of Rtcd1 91 0.54 22.93 32.43
32 INT45365 Negative_regulation of Cfp 68 0.57 25.44 32.11
33 INT5069 Negative_regulation of Mthfs 69 0.57 22.54 31.36
34 INT8027 Regulation of Gene_expression of Ngf 34 0.62 26.32 31.16
35 INT5505 Regulation of Localization of Pomc 54 0.61 6.96 30.77
36 INT66868 Positive_regulation of Ceacam3 40 0.69 26.61 28.9
37 INT13290 Binding of Atxn2l 34 0.18 1.86 28.16
38 INT52722 Localization of RETNLB 54 0.38 48.63 27.98
39 INT7565 Transcription of Pomc 69 0.72 14.46 27.41
40 INT9526 Negative_regulation of Localization of Pomc 41 0.58 6.93 23.3
41 INT5511 Negative_regulation of Gene_expression of Pomc 47 0.59 12.08 23.02
42 INT1558 Positive_regulation of Dnahc8 30 0.69 5.78 22.19
43 INT103842 Gene_expression of Cftr 53 0.78 59.59 21.82
44 INT28728 Regulation of Cfp 49 0.46 13.15 21.43
45 INT1561 Negative_regulation of Dnahc8 59 0.59 18.12 20.99
46 INT65907 Negative_regulation of Gene_expression of Ngf 36 0.59 19.5 20.03
47 INT64261 Negative_regulation of Positive_regulation of Ngf 21 0.59 16.28 19.78
48 INT2165 Localization of Cga 41 0.80 4.02 19.53
49 INT49487 Gene_expression of Sele 65 0.76 68.11 19.41
50 INT9900 Positive_regulation of Vwf 80 0.69 51.85 18.13
51 INT64051 Gene_expression of Col4a4 33 0.61 10.1 17.82
52 INT49922 Positive_regulation of Positive_regulation of Ngf 21 0.67 14.46 17.68
53 INT15358 Transcription of Ngf 29 0.72 10.43 16.94
54 INT24225 Gene_expression of Alms1 93 0.62 52.75 16.93
55 INT10323 Gene_expression of Fam166a 48 0.00 11.76 15.68
56 INT15643 Positive_regulation of Positive_regulation of Pomc 30 0.65 4.59 15.34
57 INT49147 Gene_expression of Npy1r 27 0.76 6.57 14.75
58 INT66611 Localization of Cfp 22 0.65 7.04 14.64
59 INT11855 Positive_regulation of Gene_expression of Il1rl1 19 0.69 12.22 14.57
60 INT1556 Regulation of Dnahc8 20 0.61 3.23 14.44
61 INT141615 Gene_expression of Cysltr2 2 0.72 13.44 14.09
62 INT8089 Binding of Gnrh1 47 0.48 10.04 13.99
63 INT11069 Positive_regulation of Pf4 35 0.68 27.7 13.96
64 INT8088 Regulation of Localization of Cga 28 0.60 2.37 13.91
65 INT36177 Binding of Alms1 70 0.31 35.47 13.81
66 INT13498 Gene_expression of Atxn2l 16 0.52 1.24 13.73
67 INT5207 Negative_regulation of Alms1 70 0.41 41.56 13.68
68 INT1491 Regulation of Rtcd1 33 0.53 5.17 13.4
69 INT91817 Positive_regulation of RETNLB 22 0.34 21.4 13.12
70 INT84307 Binding of Cftr 31 0.47 26.19 12.8
71 INT158124 Gene_expression of COL5A2 136 0.69 72.3 12.44
72 INT35801 Regulation of Alms1 34 0.38 20.88 12.38
73 INT114578 Positive_regulation of Gene_expression of Ceacam3 18 0.47 14.95 12.22
74 INT32054 Gene_expression of Tnc 14 0.59 9.36 12.22
75 INT159127 Gene_expression of Nps 49 0.75 16.91 12.06
76 INT5515 Negative_regulation of Positive_regulation of Pomc 25 0.58 8.73 11.88
77 INT21850 Gene_expression of Spna1 107 0.50 51.4 11.81
78 INT60590 Positive_regulation of Gbf1 25 0.39 12.5 11.79
79 INT65638 Negative_regulation of Gene_expression of Il1rl1 12 0.58 7.86 11.7
80 INT14962 Gene_expression of Pf4 27 0.76 22.48 10.88
81 INT1934 Positive_regulation of Cys1 68 0.68 60.56 10.47
82 INT25613 Gene_expression of Il1f5 32 0.77 13.29 10.44
83 INT15449 Positive_regulation of Plat 32 0.69 12.76 9.71
84 INT77282 Positive_regulation of Cftr 23 0.69 21.8 9.65
85 INT101891 Negative_regulation of Cftr 25 0.58 24.09 9.55
86 INT75997 Positive_regulation of Localization of Ngf 14 0.69 7.78 9.41
87 INT21846 Localization of Spna1 27 0.78 5.14 9.22
88 INT340600 Gene_expression of Wnt3a 1 0.68 2.14 9.14
89 INT9899 Gene_expression of Vwf 91 0.74 45.06 9.13
90 INT64849 Gene_expression of Ret 24 0.75 14.36 9.1
91 INT173587 Protein_catabolism of COL5A2 59 0.32 32.73 8.96
92 INT80420 Gene_expression of IFI27 145 0.78 63.61 8.83
93 INT121599 Negative_regulation of Gene_expression of RETNLB 7 0.21 9.28 8.8
94 INT18391 Positive_regulation of GYPA 41 0.40 16.47 8.69
95 INT55537 Positive_regulation of Coq10a 22 0.58 8.17 8.33
96 INT31125 Binding of Dpp6 10 0.36 0.22 8.26
97 INT110291 Regulation of Ceacam3 8 0.61 7 8.24
98 INT10065 Positive_regulation of Serpina6 12 0.70 1.48 8.22
99 INT95414 Positive_regulation of Alms1 40 0.41 20.3 8.1
100 INT44816 Regulation of Serpina6 16 0.62 3.63 8.02
101 INT68635 Negative_regulation of Ceacam3 7 0.55 3.16 7.85
102 INT84894 Gene_expression of Calb2 45 0.73 24.65 7.81
103 INT22491 Binding of Atrn 23 0.30 4.51 7.79
104 INT8669 Positive_regulation of Afp 66 0.70 58.21 7.67
105 INT153371 Binding of Cfp 27 0.47 7.33 7.48
106 INT6340 Negative_regulation of Atxn2l 10 0.20 0.79 7.46
107 INT12416 Regulation of Atxn2l 8 0.07 0.25 7.42
108 INT99262 Gene_expression of Defb42 16 0.31 9.99 7.38
109 INT9785 Negative_regulation of Positive_regulation of Gnrh1 18 0.43 1.88 7.35
110 INT72166 Positive_regulation of Gene_expression of RETNLB 14 0.24 10.23 7.27
111 INT10478 Protein_catabolism of Alms1 25 0.47 12.95 7.19
112 INT10513 Gene_expression of Plat 44 0.76 19.49 7.17
113 INT143996 Positive_regulation of CISH 28 0.49 17.31 7.17
114 INT49761 Regulation of Positive_regulation of Ngf 6 0.62 3.83 7.1
115 INT11839 Protein_catabolism of Pomc 15 0.98 0.77 6.99
116 INT23782 Positive_regulation of Spna1 58 0.50 35.41 6.94
117 INT150287 Positive_regulation of Ephb2 5 0.33 5.54 6.9
118 INT81608 Gene_expression of Col11a1 13 0.15 1.58 6.87
119 INT101965 Positive_regulation of Kcnj9 8 0.31 1.64 6.87
120 INT4431 Negative_regulation of Eda 10 0.46 3.53 6.81
121 INT7665 Negative_regulation of Npy1r 10 0.45 2.87 6.73
122 INT25609 Localization of Il1f5 17 0.80 10.66 6.71
123 INT3500 Positive_regulation of Gene_expression of Gnrh1 25 0.69 4.59 6.69
124 INT53311 Positive_regulation of Gene_expression of Cfp 20 0.42 4.39 6.62
125 INT87432 Regulation of Gene_expression of Il1rl1 6 0.58 4.5 6.62
126 INT72350 Positive_regulation of Npy1r 15 0.63 6.28 6.55
127 INT196192 Gene_expression of Mrgpre 21 0.77 14.87 6.53
128 INT171691 Protein_catabolism of Ecm1 31 0.20 11.57 6.38
129 INT17262 Negative_regulation of Plat 17 0.59 15.14 6.36
130 INT195 Gene_expression of C4a 16 0.48 15.55 6.1
131 INT19941 Negative_regulation of Pf4 13 0.42 10.35 5.97
132 INT32532 Regulation of Positive_regulation of Pomc 11 0.61 3.2 5.93
133 INT3905 Positive_regulation of Positive_regulation of Rtcd1 10 0.27 1.76 5.82
134 INT62611 Phosphorylation of Ngf 13 0.82 1.12 5.8
135 INT69929 Gene_expression of S100a9 11 0.77 16.12 5.79
136 INT86119 Regulation of Cftr 13 0.45 14.08 5.75
137 INT49701 Negative_regulation of Localization of Ngf 9 0.58 3.01 5.75
138 INT52020 Negative_regulation of ICA1 7 0.31 1.56 5.71
139 INT103260 Positive_regulation of Nps 35 0.48 23.8 5.67
140 INT4938 Localization of Tnc 5 0.65 1.73 5.64
141 INT131944 Gene_expression of Mki67 30 0.53 6.58 5.63
142 INT25802 Positive_regulation of Negative_regulation of Rtcd1 7 0.11 2.66 5.57
143 INT10980 Gene_expression of GYPA 40 0.78 15.32 5.51
144 INT174851 Positive_regulation of COL5A2 46 0.54 12.73 5.48
145 INT16262 Positive_regulation of Transcription of Ngf 8 0.50 4.02 5.48
146 INT36893 Negative_regulation of Coq10a 36 0.55 22.24 5.47
147 INT48840 Gene_expression of Nkx2-2 8 0.23 1.55 5.44
148 INT35928 Positive_regulation of Baat 12 0.69 12.23 5.43
149 INT201477 Positive_regulation of Acsm3 8 0.31 15 5.38
150 INT8337 Negative_regulation of Gene_expression of Gnrh1 14 0.58 4.63 5.32
151 INT10888 Binding of Vwf 32 0.46 22.87 5.21
152 INT99264 Negative_regulation of Gene_expression of Defb42 7 0.23 7.04 5.09
153 INT89546 Phosphorylation of NEFH 10 0.76 3.49 5.08
154 INT136837 Gene_expression of Bst1 2 0.34 0.74 5.07
155 INT156794 Gene_expression of CISH 41 0.58 23.09 5.03
156 INT21856 Regulation of Spna1 9 0.51 3.74 5.02
157 INT142435 Gene_expression of NES 86 0.78 47.53 4.92
158 INT26167 Positive_regulation of Hrasls 18 0.23 8.67 4.87
159 INT328620 Phosphorylation of Cfp 8 0.39 5.05 4.87
160 INT21854 Positive_regulation of Localization of Spna1 8 0.61 0.14 4.85
161 INT71528 Regulation of Col4a4 6 0.38 3.67 4.8
162 INT52952 Binding of Pdpn 8 0.13 3.57 4.79
163 INT53194 Negative_regulation of Positive_regulation of Cfp 10 0.45 4.87 4.78
164 INT69215 Gene_expression of Col1a1 38 0.68 17.39 4.77
165 INT12726 Gene_expression of Rtcd1 17 0.32 2.55 4.76
166 INT3880 Negative_regulation of Serping1 54 0.58 37.19 4.75
167 INT170757 Positive_regulation of Gene_expression of Cftr 3 0.51 11.41 4.75
168 INT8336 Transcription of Gnrh1 22 0.71 4.37 4.69
169 INT79194 Positive_regulation of Tnc 5 0.41 2.25 4.69
170 INT124375 Gene_expression of Wnt2 67 0.56 38.03 4.67
171 INT1539 Positive_regulation of MSMB 22 0.69 9.42 4.62
172 INT7575 Regulation of Transcription of Pomc 8 0.60 1.57 4.59
173 INT10806 Positive_regulation of Transcription of Pomc 13 0.50 1.74 4.58
174 INT14126 Gene_expression of Grina 13 0.67 4.63 4.57
175 INT44805 Positive_regulation of Mthfs 9 0.49 2.32 4.48
176 INT99263 Localization of Defb42 7 0.16 4.03 4.46
177 INT113107 Phosphorylation of Hist1h3f 21 0.51 8.01 4.45
178 INT28734 Gene_expression of Reln 7 0.74 5.76 4.33
179 INT83818 Positive_regulation of Localization of Cfp 5 0.32 3.6 4.33
180 INT224545 Gene_expression of Ankh 1 0.77 3.03 4.33
181 INT22337 Negative_regulation of Transcription of Pomc 12 0.59 2.17 4.32
182 INT147697 Gene_expression of ABHD2 8 0.78 8.15 4.3
183 INT47894 Regulation of Npy1r 5 0.33 3.08 4.27
184 INT27158 Negative_regulation of Positive_regulation of Rtcd1 7 0.13 1.84 4.25
185 INT745 Gene_expression of Afp 65 0.78 52.89 4.24
186 INT67441 Positive_regulation of Ugt1a10 3 0.01 0.61 4.22
187 INT15257 Positive_regulation of Nkx2-2 10 0.21 1.75 4.2
188 INT1701 Localization of Neu1 11 0.69 6.36 4.18
189 INT63977 Positive_regulation of Sele 28 0.68 18.49 4.17
190 INT139533 Binding of Il23r 17 0.47 7.67 4.14
191 INT51180 Regulation of Nkx2-2 5 0.26 2.16 4.14
192 INT32053 Positive_regulation of Gene_expression of Tnc 5 0.45 3.4 4.13
193 INT271596 Gene_expression of Pdgfrl 1 0.26 4.1 4.09
194 INT14499 Regulation of Regulation of Pomc 7 0.61 0.15 4.06
195 INT32791 Gene_expression of Dpp6 5 0.76 2.51 4.04
196 INT32933 Gene_expression of GNAS 57 0.32 10.58 4.03
197 INT51819 Negative_regulation of MSMB 8 0.49 4.5 4
198 INT126477 Gene_expression of Sdf2l1 43 0.66 22.02 3.97
199 INT61316 Gene_expression of Coq10a 59 0.73 32.81 3.95
200 INT49700 Regulation of Localization of Ngf 6 0.59 1.18 3.95
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