GO:0003677

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Name DNA binding
Categary Function
Go Slim Yes
Go Link GO:0003677
Unique Molecular Interactions 9550
Total Molecular Interactions 12629
Total Single Events 103931
Pain Genes Associated 911

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for DNA binding. They are ordered first by their pain relevance and then by number of times they were reported for DNA binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT206768 TP53 Positive_regulation of Ltp 2 0.01 5.83 10.21
2 INT11250 Cck Positive_regulation of Gene_expression of Fos 14 0.78 0.08 7.29
3 INT338167 Binding of CDKN2A and MC1R 1 0.42 6.14 5.76
4 INT296275 Binding of Dlg4 and Kcnip3 1 0.39 3.58 5.6
5 INT170447 Binding of Pax3 and Spr 1 0.01 0.1 5.37
6 INT126335 Binding of Pax3 and Tac1 6 0.07 6.22 5.27
7 INT182124 Binding of IRF6 and TLR4 14 0.10 16.11 4.65
8 INT51497 Cck Negative_regulation of Localization of Trim13 1 0.34 0 4.53
9 INT186566 Hpcl1 Positive_regulation of Fos 1 0.17 0.38 4.49
10 INT29240 Binding of POMC and YY1 5 0.40 0.17 4.06
11 INT200322 Binding of Rest and Sp3 1 0.39 2.93 3.98
12 INT113080 Drd1a Positive_regulation of Phosphorylation of Creb1 2 0.27 0.43 3.88
13 INT220623 Binding of Stat1 and Bace1 11 0.25 10.33 3.81
14 INT11252 Cck Positive_regulation of Fos 6 0.78 0 3.79
15 INT104977 MITF Regulation of Gene_expression of MC1R 1 0.69 0.91 3.71
16 INT322411 Hist1h1t Positive_regulation of Positive_regulation of OPRM1 1 0.00 1.25 3.63
17 INT115690 Negative_regulation of Prkcg Negative_regulation of Gene_expression of Fos 1 0.47 0.72 3.63
18 INT17317 Binding of Jun and Fos 7 0.42 1.03 3.5
19 INT180984 IRF6 Positive_regulation of Localization of IL8 7 0.11 2.13 3.47
20 INT69823 Binding of GHR and RYBP 1 0.01 0 3.23
21 INT108810 Esr1 Positive_regulation of Binding of Oprm1 1 0.51 1.79 3.22
22 INT289979 Binding of Helt and Negative_regulation of Maoa 1 0.00 0.17 3.14
23 INT94204 NCOR2 Regulation of Gene_expression of SP5 1 0.02 2.15 3.12
24 INT161164 Prkcg Regulation of Phosphorylation of Creb1 3 0.41 0.62 3.11
25 INT309150 Edc4 Positive_regulation of Creb1 1 0.03 3.46 3.09
26 INT123451 Binding of YY1 and Adra2a 1 0.37 0 2.98
27 INT113234 Binding of Pax3 and Tacr1 3 0.12 1.54 2.93
28 INT168758 Hist1h1t Positive_regulation of Phosphorylation of Akt1 2 0.02 0.44 2.79
29 INT190167 Binding of JUN and MMP12 1 0.26 0.82 2.76
30 INT127621 Bst1 Regulation of Positive_regulation of Fos 1 0.26 0 2.73
31 INT140347 Binding of ATP1A2 and Cacna1a 1 0.11 2.88 2.73
32 INT154188 Il6 Positive_regulation of Gene_expression of Atf3 1 0.76 3.07 2.71
33 INT30133 Binding of Cck and Penk 1 0.27 2.49 2.71
34 INT151381 St8sia1 Positive_regulation of Cck 1 0.19 0.45 2.7
35 INT91350 Binding of Pla2g4a and RYBP 1 0.00 1.15 2.65
36 INT67905 Binding of Spn and Fosl1 1 0.24 2.1 2.54
37 INT294909 Pax3 Positive_regulation of Gene_expression of Il6 1 0.09 5.43 2.51
38 INT113715 Msh3 Positive_regulation of tf 1 0.11 0 2.47
39 INT170038 Gtf3a Regulation of Gene_expression of DRGX 1 0.00 1.36 2.46
40 INT117532 SETBP1 Positive_regulation of Gene_expression of TNF 1 0.54 0.85 2.44
41 INT135867 Zfp821 Positive_regulation of Positive_regulation of Chrne 1 0.01 0 2.44
42 INT214144 Cck Positive_regulation of Pomc 1 0.15 0.94 2.39
43 INT74840 Binding of Cacna1a and Cacna1a 5 0.00 4.24 2.36
44 INT153728 RYBP Positive_regulation of Gpt 3 0.03 2.01 2.36
45 INT238914 Positive_regulation of CNR1 Positive_regulation of Phosphorylation of MAPK1 1 0.19 3.22 2.35
46 INT214159 Cck Positive_regulation of Nts 1 0.03 0.93 2.34
47 INT322410 Hist1h1t Positive_regulation of Phosphorylation of OPRM1 1 0.00 0.08 2.31
48 INT54489 Binding of Jun and Rabep2 4 0.16 1.48 2.3
49 INT156622 Umod Regulation of Phosphorylation of Creb1 1 0.05 0.33 2.27
50 INT279361 Binding of TNF and KLF1 4 0.00 3.72 2.19
51 INT146520 Tmem132a Regulation of Gene_expression of Fos 1 0.69 0.5 2.18
52 INT209924 IL1B Negative_regulation of PPARA 1 0.20 4.38 2.17
53 INT184262 Binding of AGER and HMGB1 1 0.34 4.49 2.17
54 INT39108 Binding of PDYN and YY1 2 0.50 0.44 2.14
55 INT319581 Binding of PIAS1 and TNFSF14 1 0.02 1.58 2.13
56 INT66157 Binding of ALB and BDP1 1 0.11 0 2.13
57 INT135868 Zfp821 Positive_regulation of Binding of ACAA1 1 0.00 0 2.11
58 INT356313 Crh Positive_regulation of Localization of Helt 1 0.02 0 2.11
59 INT63919 Binding of Cck and Insrr 1 0.01 0 2.08
60 INT63918 Binding of Cck and Ripk2 1 0.28 0 2.07
61 INT158964 FosB Negative_regulation of Creb1 1 0.21 0 2.07
62 INT114927 Positive_regulation of Binding of Oprm1 and Creb1 1 0.17 0.28 2.07
63 INT296277 Binding of Car2 and Kcnip3 5 0.18 1.09 2.06
64 INT190524 Ros1 Positive_regulation of Nfkb1 3 0.02 4.24 2.06
65 INT114923 Binding of Oprm1 and Creb1 1 0.16 0.28 2.06
66 INT88883 IRF6 Positive_regulation of Nfkb1 1 0.11 0.53 2.01
67 INT124133 Camk2a Regulation of Phosphorylation of Creb1 1 0.46 0 2
68 INT274372 Phc1 Negative_regulation of Slc6a3 1 0.06 0.47 1.99
69 INT213973 Binding of Pax3 and Mthfd1 1 0.00 0.16 1.99
70 INT117794 Hpcl1 Positive_regulation of Gene_expression of Fos 3 0.17 0.15 1.98
71 INT54488 Npepo Regulation of Gene_expression of Jun 1 0.30 0 1.98
72 INT53751 Positive_regulation of Cyp2e1 Positive_regulation of RYBP 1 0.14 0.89 1.98
73 INT217042 IRF6 Positive_regulation of TNF 4 0.27 3.03 1.95
74 INT129212 RYBP Positive_regulation of Tnf 2 0.03 1.9 1.95
75 INT227493 Binding of TCEA1 and SIRT2 1 0.01 1.55 1.93
76 INT125348 Decr1 Regulation of Gene_expression of Fos 1 0.00 0.1 1.92
77 INT116815 Binding of Pias1 and Ppbp 1 0.36 0.86 1.92
78 INT351281 AP1M2 Regulation of NCOR2 1 0.00 0.85 1.9
79 INT186435 Prkcg Regulation of Creb1 1 0.44 0.45 1.9
80 INT186432 Prkaca Regulation of Creb1 1 0.14 0.45 1.9
81 INT129903 Nr1i2 Regulation of Cyp3a11 1 0.64 1.26 1.9
82 INT355251 Cacna1a Regulation of Gene_expression of Gabrg1 1 0.01 0.06 1.86
83 INT355249 Cacna1a Regulation of Gene_expression of Ltp 1 0.04 0.06 1.86
84 INT50993 Il1b Positive_regulation of Fos 2 0.40 0.43 1.84
85 INT155460 Tnfrsf1a Positive_regulation of Positive_regulation of Nfkb1 1 0.42 2.39 1.82
86 INT112526 D2Mit212 Negative_regulation of Gene_expression of Fos 1 0.03 0.28 1.8
87 INT334345 Binding of GRP and Helt 1 0.02 0 1.79
88 INT115048 Kcnip3 Regulation of Gene_expression of Pdyn 2 0.27 0.71 1.78
89 INT146512 Tmem132a Negative_regulation of Gene_expression of Fos 1 0.23 0 1.76
90 INT104709 Msh3 Positive_regulation of Rbm39 1 0.01 0.07 1.76
91 INT139640 Jun Regulation of Gene_expression of Npy 1 0.21 1.98 1.75
92 INT142073 Binding of Helt and Nrm 1 0.00 0 1.74
93 INT86997 Binding of HIVEP1 and NGF 2 0.03 1.75 1.73
94 INT92369 Binding of CYP2D6 and RYBP 1 0.25 0.15 1.73
95 INT94203 SP5 Positive_regulation of FOS 1 0.25 1.41 1.72
96 INT137207 Tnf Positive_regulation of Nfkb1 3 0.23 2.69 1.71
97 INT175986 Ros1 Positive_regulation of Gtf3a 2 0.01 4.75 1.71
98 INT186433 Trib3 Regulation of Phosphorylation of Creb1 1 0.03 0.32 1.71
99 INT148090 Binding of CALCA and NCOR2 1 0.00 0.65 1.71
100 INT108129 GDNF Regulation of Gene_expression of GRHL3 1 0.21 0.39 1.71
101 INT200335 Binding of Oprm1 and Rest 1 0.40 0.07 1.7
102 INT62065 Binding of YY1 and Penk 3 0.14 0 1.69
103 INT215100 Binding of Hmgb1 and Tlr4 5 0.29 3.21 1.68
104 INT160304 Npy Regulation of Gene_expression of Fos 3 0.67 1.43 1.68
105 INT347396 RYBP Positive_regulation of Binding of Sdcbp 1 0.00 0.92 1.66
106 INT191618 Binding of App and Nf1 1 0.35 3.77 1.65
107 INT54484 Npepo Positive_regulation of Gene_expression of Fos 1 0.43 0 1.63
108 INT155459 Tnfrsf1a Positive_regulation of Nfkb1 1 0.42 2.45 1.63
109 INT215096 Binding of Hmgb1 and Tlr2 9 0.38 11.61 1.61
110 INT335405 Binding of Arntl and Npas2 1 0.28 1.82 1.61
111 INT73116 TYMS Negative_regulation of DNMT3B 1 0.24 0 1.6
112 INT167200 Gtf3a Regulation of Gene_expression of Ngf 1 0.08 1.47 1.6
113 INT73115 TYMS Negative_regulation of Positive_regulation of DNMT3B 1 0.24 0 1.6
114 INT48790 Negative_regulation of Rtcd1 Negative_regulation of Pax3 1 0.02 0 1.59
115 INT105112 Plat Positive_regulation of JUN 1 0.01 1.55 1.58
116 INT355254 Ltp Regulation of Cacna1a 1 0.04 0 1.58
117 INT149632 Binding of HK1 and NCOR2 1 0.01 0.13 1.58
118 INT131574 Negative_regulation of Ephb1 Negative_regulation of Gene_expression of Creb1 1 0.41 0.33 1.58
119 INT266406 Binding of APP and Ager 1 0.00 2.34 1.57
120 INT212660 Nr3c1 Regulation of KCNA1 1 0.00 1.25 1.57
121 INT144280 ACP1 Negative_regulation of Phosphorylation of MAPK1 1 0.37 0.78 1.56
122 INT347397 RYBP Positive_regulation of Sdcbp 1 0.00 0.22 1.56
123 INT114926 Creb1 Negative_regulation of Positive_regulation of Oprm1 1 0.13 0.23 1.56
124 INT74843 Binding of Cacna1a and Ea2 3 0.13 3.29 1.55
125 INT333150 Tlx2 Regulation of asa 1 0.04 2.17 1.55
126 INT158877 PRS Positive_regulation of Gene_expression of Fos 1 0.09 5.14 1.54
127 INT100784 RYBP Positive_regulation of CYP3A4 1 0.44 0 1.54
128 INT167201 Gtf3a Regulation of TNF 1 0.01 1.39 1.52
129 INT256360 Car2 Positive_regulation of Localization of Rela 1 0.14 0 1.51
130 INT79021 Regulation of Binding of Jun and Fos 2 0.50 0.66 1.5
131 INT121747 Prkcg Negative_regulation of Positive_regulation of Creb1 1 0.16 0.2 1.5
132 INT117008 Sfpi1 Regulation of Oprm1 1 0.56 0.56 1.49
133 INT293009 IRF6 Positive_regulation of Positive_regulation of CA2 1 0.04 0.66 1.49
134 INT121741 Prkaca Negative_regulation of Positive_regulation of Creb1 1 0.10 0.2 1.49
135 INT298283 Pou4f1 Positive_regulation of Gene_expression of Runx1 1 0.50 1.4 1.48
136 INT156008 Bcl2 Regulation of Localization of Aifm1 1 0.17 1.92 1.47
137 INT30042 Binding of YY1 and Gnrhr 1 0.18 0 1.47
138 INT276687 Pax3 Positive_regulation of Nkx1-1 1 0.00 0.59 1.47
139 INT27932 Binding of CCK and NCOR2 1 0.01 0.91 1.47
140 INT73650 Binding of Pim3 and Creb1 1 0.03 2.48 1.47
141 INT104975 MITF Regulation of Transcription of PRSS1 1 0.68 0.35 1.46
142 INT104972 MITF Regulation of Transcription of TYR 1 0.20 0.35 1.45
143 INT6976 Helt Regulation of Gene_expression of St8sia1 1 0.00 0.07 1.45
144 INT72319 Adarb1 Positive_regulation of Gene_expression of Fos 3 0.10 0.1 1.44
145 INT318491 IRF6 Positive_regulation of FPR2 1 0.10 6.14 1.44
146 INT131156 Binding of RUNX1 and TNF 2 0.03 3.44 1.42
147 INT157540 Binding of SP1 and YY1 1 0.41 2.55 1.42
148 INT154114 PENK Positive_regulation of YY1 1 0.50 0.06 1.41
149 INT28992 Tmpo Positive_regulation of Pomc 1 0.36 3.18 1.41
150 INT154113 POMC Positive_regulation of YY1 1 0.70 0.06 1.41
151 INT68723 Pomgnt1 Negative_regulation of Gene_expression of Fos 1 0.12 0 1.41
152 INT222213 TFAM Positive_regulation of Gene_expression of Ccr1 1 0.02 3.96 1.4
153 INT79745 Gtf3a Positive_regulation of Positive_regulation of Sst 1 0.09 0 1.4
154 INT108583 Binding of Vip and Fos 1 0.36 0 1.39
155 INT355250 Ltp Regulation of Positive_regulation of Cacna1a 1 0.04 0 1.39
156 INT162105 Nr4a3 Regulation of ACPT-I 1 0.10 0.26 1.38
157 INT168724 Creb1 Negative_regulation of Gene_expression of Calca 1 0.46 1.09 1.38
158 INT167169 Nfkb1 Regulation of Gene_expression of Crp 1 0.09 1.76 1.38
159 INT168721 Positive_regulation of Creb1 Positive_regulation of Calca 1 0.53 1.07 1.37
160 INT106850 P2ry2 Positive_regulation of Phosphorylation of Creb1 2 0.49 0.73 1.36
161 INT168722 Creb1 Positive_regulation of Calca 1 0.73 1.05 1.35
162 INT158079 Binding of Esr1 and Gper 1 0.31 0.97 1.35
163 INT222182 Binding of ESR1 and HLA-DRB2 1 0.00 3.1 1.35
164 INT140532 Gtf3a Positive_regulation of DYT10 1 0.12 1.83 1.34
165 INT355253 Ltp Positive_regulation of Cacna1a 1 0.05 0 1.34
166 INT294775 IRF6 Positive_regulation of TLR4 6 0.08 2.04 1.32
167 INT94630 Positive_regulation of Adarb1 Positive_regulation of Gene_expression of Fos 2 0.03 0.1 1.32
168 INT356326 Crhr1 Regulation of Gene_expression of Helt 1 0.01 0.65 1.32
169 INT39950 Binding of ALB and PDYN 1 0.31 0 1.32
170 INT120929 Prkcg Regulation of Gene_expression of Fos 2 0.50 0.34 1.31
171 INT150890 Binding of Esr1 and Esr2 2 0.52 2.06 1.31
172 INT355252 Binding of Cacna1a and Cnr1 1 0.04 0 1.31
173 INT131886 Creb1 Positive_regulation of Gene_expression of Prkcg 1 0.03 0 1.31
174 INT131256 Positive_regulation of Nfkb1 Positive_regulation of Gene_expression of Nfkbia 1 0.38 0.94 1.31
175 INT192080 Foxm1 Positive_regulation of Cnr1 2 0.14 0.72 1.3
176 INT148778 Binding of Usf1 and Rtn1 1 0.40 0.85 1.3
177 INT66428 Dcc Positive_regulation of Fos 2 0.05 0.39 1.29
178 INT148775 Binding of Calca and Usf1 1 0.43 0.85 1.29
179 INT89878 Pdyn Positive_regulation of Gene_expression of Nkx2-5 1 0.35 0 1.29
180 INT48881 TWIST1 Positive_regulation of Localization of Abat 1 0.02 0.44 1.29
181 INT121802 DEAF1 Negative_regulation of HTR1A 1 0.46 0.88 1.29
182 INT89873 Pdyn Positive_regulation of Gene_expression of Gata4 1 0.23 0 1.29
183 INT114929 Positive_regulation of Binding of Oprm1 and Crebbp 1 0.06 0.14 1.28
184 INT89876 Pdyn Positive_regulation of Gata4 1 0.23 0 1.28
185 INT136644 T(1;9)27H Negative_regulation of Gene_expression of Hand1 1 0.15 1.14 1.27
186 INT73398 Binding of Pnoc and Nr1d2 1 0.10 0 1.27
187 INT114925 Binding of Oprm1 and Crebbp 1 0.06 0.14 1.27
188 INT124099 Binding of GGT5 and RYBP 1 0.00 0.34 1.26
189 INT124767 Creb1 Regulation of Oprm1 1 0.45 0 1.26
190 INT84886 APC Regulation of PPARD 1 0.51 1.57 1.26
191 INT114635 Hmox2 Positive_regulation of Gene_expression of Fos 1 0.47 0.88 1.26
192 INT124108 Binding of RYBP and Ccne1 1 0.09 0.34 1.26
193 INT287104 Binding of Ntrk2 and T 1 0.20 3.29 1.26
194 INT352269 Binding of Jund and Adora1 1 0.15 1.2 1.25
195 INT118784 Thop1 Positive_regulation of Protein_catabolism of Pax3 1 0.07 0.07 1.25
196 INT162163 CDKN2A Positive_regulation of PLD2 1 0.24 0 1.24
197 INT167278 Binding of OPRM1 and REST 1 0.08 0.94 1.24
198 INT136250 Phosphorylation of Tff3 Regulation of Creb1 1 0.02 0.18 1.24
199 INT141244 Fos Regulation of Prkaca 1 0.18 0.07 1.24
200 INT71443 CSAD Positive_regulation of Gene_expression of Fos 1 0.58 0.81 1.23

Single Events

The table below shows the top 100 pain related interactions that have been reported for DNA binding. They are ordered first by their pain relevance and then by number of times they were reported in DNA binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5200 Gene_expression of Fos 3083 0.78 894.43 1639.02
2 INT5202 Positive_regulation of Gene_expression of Fos 1163 0.70 319.28 684
3 INT5228 Positive_regulation of Fos 934 0.70 209.8 503.87
4 INT6056 Negative_regulation of Gene_expression of Fos 601 0.59 193.05 386.84
5 INT5379 Gene_expression of Fos 656 0.78 255.5 292.54
6 INT5591 Regulation of Gene_expression of Fos 425 0.62 129.06 265.78
7 INT11009 Phosphorylation of Creb1 458 0.82 111.34 221.97
8 INT11012 Positive_regulation of Creb1 258 0.70 84.4 132
9 INT5380 Positive_regulation of Gene_expression of Fos 243 0.70 105.65 131.05
10 INT115386 Gene_expression of Ppara 779 0.77 549.99 128.36
11 INT65054 Positive_regulation of Nfkb1 285 0.70 149.33 126.73
12 INT11011 Positive_regulation of Phosphorylation of Creb1 190 0.70 49.25 112.01
13 INT49651 Gene_expression of Creb1 276 0.78 114.77 111.96
14 INT27096 Positive_regulation of Nfkb1 325 0.70 195.11 109.06
15 INT5587 Regulation of Fos 191 0.62 40.81 99.7
16 INT65500 Gene_expression of App 605 0.78 429.94 98.31
17 INT7944 Positive_regulation of Fos 193 0.70 60.69 98.31
18 INT86024 Gene_expression of PPARA 736 0.78 497.93 91.14
19 INT6437 Binding of YY1 154 0.47 26.3 90.46
20 INT71789 Positive_regulation of MAPK1 396 0.70 234.44 89.27
21 INT22967 Positive_regulation of RYBP 94 0.56 37.04 85.92
22 INT84546 Positive_regulation of Ppara 481 0.70 334.21 83.45
23 INT8534 Localization of Pax3 85 0.59 28.71 82.82
24 INT5590 Negative_regulation of Fos 144 0.59 40.94 81.98
25 INT133211 Gene_expression of Runx1 169 0.77 83.4 76.16
26 INT6656 Gene_expression of YY1 135 0.75 24.73 72.16
27 INT57380 Phosphorylation of Creb1 213 0.82 66.8 71.26
28 INT14624 Gene_expression of Pax3 100 0.38 33.22 69.47
29 INT9484 Gene_expression of Jun 175 0.78 34.89 68.54
30 INT5861 Gene_expression of Egr1 203 0.78 49.35 68.13
31 INT5374 Gene_expression of Esr1 412 0.77 263.89 67.34
32 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64
33 INT67614 Positive_regulation of PPARA 438 0.68 293.28 63.61
34 INT11318 Gene_expression of Gtf3a 274 0.52 183.82 60.89
35 INT546 Binding of ALB 311 0.48 85.98 60.14
36 INT102020 Gene_expression of Creb1 190 0.78 57.31 59.77
37 INT82055 Positive_regulation of Creb1 176 0.70 60.2 58.39
38 INT6436 Positive_regulation of Positive_regulation of Fos 101 0.70 18.71 57.96
39 INT18883 Negative_regulation of RYBP 53 0.56 21.14 57.52
40 INT6669 Negative_regulation of Positive_regulation of Fos 98 0.59 23.5 56.82
41 INT8528 Negative_regulation of Gene_expression of Fos 100 0.59 41.15 55.6
42 INT69876 Negative_regulation of Nfkb1 147 0.58 89.81 55.5
43 INT20375 Gene_expression of Hand1 213 0.60 148.51 54.53
44 INT48642 Positive_regulation of TCEA1 92 0.70 24.59 53.64
45 INT122041 Binding of Ppara 308 0.48 189.17 51.48
46 INT20382 Gene_expression of Hand2 211 0.66 142.26 51.05
47 INT6796 Positive_regulation of Jun 165 0.70 37.18 49.64
48 INT4345 Gene_expression of Gtf3a 157 0.67 80.75 48.47
49 INT117598 Regulation of ACR 118 0.26 41.25 48.01
50 INT789 Positive_regulation of YY1 69 0.67 14.07 47.06
51 INT66331 Gene_expression of Cacna1a 101 0.78 49.58 46.32
52 INT4656 Localization of RYBP 49 0.77 5.28 46.21
53 INT71786 Phosphorylation of MAPK1 256 0.82 110.09 46.17
54 INT3361 Positive_regulation of Esr1 273 0.69 208.53 44.81
55 INT88617 Positive_regulation of Gene_expression of Creb1 90 0.69 51.69 44.29
56 INT935 Localization of Gtf3a 124 0.70 35.72 43.3
57 INT52531 Gene_expression of Nfkb1 153 0.75 82.84 42.9
58 INT613 Gene_expression of Alb 268 0.78 149.84 42.78
59 INT4913 Binding of Pax3 52 0.28 9.57 42.67
60 INT11180 Binding of RYBP 52 0.46 13.86 42.53
61 INT60388 Gene_expression of Helt 90 0.07 19.18 41.72
62 INT7824 Regulation of Cck 39 0.62 5.31 39.28
63 INT26698 Positive_regulation of Cacna1a 37 0.67 26.33 39.1
64 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75
65 INT107576 Gene_expression of Atf3 114 0.78 72.42 38.64
66 INT163134 Gene_expression of ACR 78 0.65 30.39 38.48
67 INT18774 Gene_expression of RYBP 67 0.65 47.66 37.59
68 INT9082 Positive_regulation of ESR1 238 0.69 148.51 36.69
69 INT3971 Positive_regulation of Alb 175 0.70 98.46 36.45
70 INT65055 Negative_regulation of Nfkb1 83 0.58 44.85 34.94
71 INT103094 Binding of PPARA 308 0.47 177.26 34.75
72 INT11013 Negative_regulation of Phosphorylation of Creb1 55 0.59 18.74 34.66
73 INT21527 Gene_expression of FosB 47 0.78 11.2 34.39
74 INT67613 Positive_regulation of PPARG 94 0.70 69.15 34.38
75 INT7833 Positive_regulation of Cck 33 0.70 8.54 34.21
76 INT5862 Positive_regulation of Egr1 82 0.70 30.4 33.96
77 INT666 Gene_expression of Jun 124 0.78 54.61 33.67
78 INT16714 Regulation of Creb1 64 0.62 22.23 33.56
79 INT65536 Negative_regulation of Positive_regulation of Nfkb1 77 0.59 38.86 33.33
80 INT234 Binding of Alb 151 0.48 52.34 32.97
81 INT81530 Gene_expression of Nfkb1 93 0.78 48.58 32.58
82 INT9796 Gene_expression of Cck 63 0.78 11.44 32.09
83 INT6053 Transcription of Fos 107 0.72 20.97 31.88
84 INT47764 Binding of Jun 106 0.48 22.62 31.39
85 INT29743 Negative_regulation of App 91 0.59 65.56 31.26
86 INT6058 Localization of Fos 73 0.81 16.7 30.84
87 INT57379 Positive_regulation of Phosphorylation of Creb1 79 0.69 28.24 30.25
88 INT6660 Positive_regulation of Jun 148 0.69 67.58 29.73
89 INT724 Negative_regulation of Alb 151 0.59 93.57 29.65
90 INT11796 Positive_regulation of Helt 52 0.31 11.7 29.22
91 INT11010 Regulation of Phosphorylation of Creb1 52 0.62 7.26 29.04
92 INT6855 Binding of NCOR2 71 0.41 15.64 28.96
93 INT47712 Positive_regulation of App 135 0.69 101.38 28.94
94 INT53384 Positive_regulation of FosB 41 0.69 8.43 28.91
95 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8
96 INT122039 Positive_regulation of Gene_expression of Ppara 144 0.68 113.55 28.55
97 INT9199 Positive_regulation of CEBPZ 111 0.67 30.99 28.45
98 INT87212 Negative_regulation of Positive_regulation of Nfkb1 74 0.57 38.21 28.31
99 INT6584 Negative_regulation of Pax3 31 0.39 14.64 27.97
100 INT83708 Negative_regulation of MAPK1 156 0.57 84.93 27.85
101 INT22045 Gene_expression of IRF6 158 0.75 58.07 27.81
102 INT6717 Negative_regulation of YY1 45 0.57 15.35 27.8
103 INT115385 Negative_regulation of Ppara 154 0.58 129.05 27.58
104 INT64499 Positive_regulation of IRF6 123 0.49 52.73 27.51
105 INT37296 Binding of Esr1 117 0.43 62.51 27.33
106 INT5206 Gene_expression of AR 316 0.78 113.83 27.29
107 INT17331 Positive_regulation of JUN 132 0.69 60.4 27.03
108 INT3760 Positive_regulation of ALB 142 0.70 87.46 26.7
109 INT16428 Positive_regulation of Gtf3a 135 0.20 106.44 26.67
110 INT7832 Localization of Cck 39 0.81 6.81 26.54
111 INT5378 Regulation of Gene_expression of Fos 47 0.60 14.47 26.41
112 INT65537 Positive_regulation of Positive_regulation of Nfkb1 52 0.67 30.6 26.35
113 INT20462 Binding of ESR1 210 0.44 102.7 26.34
114 INT79395 Gene_expression of Twist1 193 0.77 100.06 26.34
115 INT53385 Positive_regulation of Gene_expression of FosB 26 0.70 9.18 26.33
116 INT6054 Positive_regulation of Gene_expression of Egr1 67 0.70 18.45 25.93
117 INT28336 Positive_regulation of Pax3 37 0.33 20.94 25.66
118 INT89662 Positive_regulation of Gene_expression of App 169 0.70 133.36 25.62
119 INT12124 Gene_expression of MAPK1 141 0.75 82.4 25.58
120 INT67610 Positive_regulation of Pparg 53 0.70 31.91 25.2
121 INT41487 Negative_regulation of Cacna1a 16 0.57 9.42 25.2
122 INT19986 Negative_regulation of Cck 31 0.59 4.32 24.99
123 INT57874 Gene_expression of Egr1 113 0.78 68.46 24.95
124 INT5199 Gene_expression of Fosl1 44 0.78 8.66 24.8
125 INT27933 Gene_expression of NCOR2 65 0.72 31.35 24.23
126 INT17275 Gene_expression of HIVEP1 267 0.75 232.07 24.06
127 INT44954 Gene_expression of APP 191 0.78 105.86 23.9
128 INT7827 Binding of Cck 32 0.48 4.66 23.73
129 INT66758 Binding of Nfkb1 97 0.48 50.65 23.65
130 INT35716 Positive_regulation of NCOR2 45 0.60 18 23.54
131 INT102021 Positive_regulation of Gene_expression of Creb1 66 0.70 24.04 23.28
132 INT114362 Localization of Hmgb1 127 0.78 120.28 23.26
133 INT18884 Regulation of RYBP 25 0.38 11.43 23.2
134 INT61160 Negative_regulation of Gene_expression of Creb1 37 0.59 17.95 23.17
135 INT71875 Localization of Nfkb1 92 0.78 48.13 22.94
136 INT129157 Positive_regulation of Atf3 48 0.69 35.42 22.87
137 INT823 Negative_regulation of ESR1 144 0.58 63.72 22.52
138 INT7678 Localization of Alb 142 0.81 80.93 22.49
139 INT106175 Positive_regulation of Positive_regulation of Creb1 37 0.70 13.89 22.46
140 INT19949 Regulation of Positive_regulation of Fos 36 0.60 6.11 22.05
141 INT84732 Positive_regulation of Hand2 81 0.69 62.07 22
142 INT61116 Positive_regulation of Ppara 119 0.69 58.62 21.6
143 INT16396 Negative_regulation of CEBPZ 76 0.48 30.03 21.6
144 INT73625 Gene_expression of PPARG 108 0.78 104.85 21.42
145 INT101517 Negative_regulation of PPARA 168 0.57 112.24 21.41
146 INT5586 Binding of Fos 47 0.48 12.7 21.33
147 INT43226 Gene_expression of Hivep3 75 0.71 30.53 21.14
148 INT97798 Localization of IRF6 86 0.73 33.27 20.94
149 INT52529 Regulation of Nfkb1 48 0.61 26.2 20.89
150 INT11625 Localization of App 98 0.78 55.46 20.86
151 INT69877 Positive_regulation of Positive_regulation of Nfkb1 53 0.68 31.44 20.7
152 INT85952 Positive_regulation of AR 168 0.67 64.36 20.66
153 INT5096 Positive_regulation of Gtf3a 79 0.60 42.26 20.62
154 INT61159 Regulation of Gene_expression of Creb1 46 0.62 24.07 20.52
155 INT16794 Binding of App 103 0.48 64.87 19.79
156 INT67608 Gene_expression of Pparg 41 0.78 25.09 19.53
157 INT65502 Regulation of App 77 0.62 52.05 19.44
158 INT3359 Regulation of YY1 32 0.60 8.19 19.2
159 INT101188 Gene_expression of Rela 81 0.56 23.43 19.15
160 INT91462 Positive_regulation of Phosphorylation of MAPK1 99 0.67 40.28 18.99
161 INT9482 Positive_regulation of Gene_expression of Jun 60 0.69 9.95 18.61
162 INT56749 Gene_expression of PCNA 219 0.77 111.25 18.42
163 INT3952 Negative_regulation of ALB 116 0.59 72.18 18.35
164 INT11275 Regulation of Fos 37 0.60 5.79 18.18
165 INT62577 Negative_regulation of Creb1 55 0.59 19.68 18.1
166 INT61158 Negative_regulation of Creb1 33 0.59 11.54 18.06
167 INT112017 Regulation of Hand2 77 0.36 62.23 18.04
168 INT13244 Binding of Helt 30 0.31 4.56 18.01
169 INT107454 Positive_regulation of Stat3 43 0.68 19.63 17.69
170 INT4067 Negative_regulation of Esr1 97 0.50 43.45 17.52
171 INT8526 Negative_regulation of Positive_regulation of Fos 26 0.59 5.99 17.52
172 INT31136 Binding of Cacna1a 28 0.45 30.76 17.35
173 INT70557 Negative_regulation of Localization of Pax3 1 0.36 1.15 17.32
174 INT17237 Regulation of Esr1 74 0.43 49.09 17.25
175 INT134298 Gene_expression of Ptges2 96 0.54 56.52 17.19
176 INT94467 Positive_regulation of Hand1 71 0.58 59 16.96
177 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71
178 INT102023 Regulation of Creb1 51 0.62 16.29 16.71
179 INT23657 Positive_regulation of APP 64 0.70 39.76 16.68
180 INT93361 Gene_expression of Trp53 208 0.78 175.35 16.65
181 INT104045 Regulation of Hand1 65 0.35 51.32 16.26
182 INT80972 Gene_expression of Tp53 104 0.78 102.74 16.02
183 INT61117 Gene_expression of Ppara 158 0.68 69.3 15.98
184 INT65659 Positive_regulation of STAT3 132 0.70 69.56 15.95
185 INT3793 Regulation of CEBPZ 59 0.61 20.91 15.83
186 INT9750 Positive_regulation of Rara 39 0.66 12.44 15.83
187 INT92354 Localization of ESR1 77 0.75 33.04 15.51
188 INT75531 Regulation of MAPK1 70 0.61 34.39 15.42
189 INT615 Regulation of Alb 66 0.62 33.43 15.33
190 INT73916 Gene_expression of Esr1 58 0.77 26.59 15.15
191 INT41558 Localization of Sp1 9 0.48 0.56 14.9
192 INT129584 Positive_regulation of Stat3 97 0.68 87.07 14.86
193 INT93482 Localization of Rela 56 0.78 24.52 14.82
194 INT11795 Negative_regulation of Helt 33 0.28 6.51 14.76
195 INT54052 Gene_expression of App 33 0.78 25.08 14.7
196 INT60197 Gene_expression of JUN 90 0.78 42.32 14.61
197 INT103096 Regulation of PPARA 113 0.60 62.47 14.57
198 INT40478 Negative_regulation of NCOR2 23 0.48 12.77 14.56
199 INT107575 Positive_regulation of Gene_expression of Atf3 25 0.69 27.37 14.55
200 INT100139 Positive_regulation of Gene_expression of PPARA 160 0.63 97.78 14.53
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