GO:0003682

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Name chromatin binding
Categary Function
Go Slim No
Go Link GO:0003682
Unique Molecular Interactions 2099
Total Molecular Interactions 2753
Total Single Events 19694
Pain Genes Associated 233

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for chromatin binding. They are ordered first by their pain relevance and then by number of times they were reported for chromatin binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT206768 TP53 Positive_regulation of Ltp 2 0.01 5.83 10.21
2 INT170447 Binding of Pax3 and Spr 1 0.01 0.1 5.37
3 INT126335 Binding of Pax3 and Tac1 6 0.07 6.22 5.27
4 INT200322 Binding of Rest and Sp3 1 0.39 2.93 3.98
5 INT108810 Esr1 Positive_regulation of Binding of Oprm1 1 0.51 1.79 3.22
6 INT113234 Binding of Pax3 and Tacr1 3 0.12 1.54 2.93
7 INT294909 Pax3 Positive_regulation of Gene_expression of Il6 1 0.09 5.43 2.51
8 INT161190 CRX Regulation of Gene_expression of Ntrk2 1 0.04 3.05 2.06
9 INT274372 Phc1 Negative_regulation of Slc6a3 1 0.06 0.47 1.99
10 INT213973 Binding of Pax3 and Mthfd1 1 0.00 0.16 1.99
11 INT14991 SFTPA1 Positive_regulation of Localization of MPO 1 0.11 1.65 1.92
12 INT200335 Binding of Oprm1 and Rest 1 0.40 0.07 1.7
13 INT341372 CRX Positive_regulation of Gene_expression of Crh 1 0.04 1.81 1.7
14 INT93470 Notch1 Positive_regulation of Localization of Prkcg 2 0.09 0.31 1.65
15 INT48790 Negative_regulation of Rtcd1 Negative_regulation of Pax3 1 0.02 0 1.59
16 INT212660 Nr3c1 Regulation of KCNA1 1 0.00 1.25 1.57
17 INT256360 Car2 Positive_regulation of Localization of Rela 1 0.14 0 1.51
18 INT276687 Pax3 Positive_regulation of Nkx1-1 1 0.00 0.59 1.47
19 INT222213 TFAM Positive_regulation of Gene_expression of Ccr1 1 0.02 3.96 1.4
20 INT161189 CRX Regulation of Gene_expression of Rvm 1 0.00 2 1.39
21 INT161191 CRX Regulation of Gene_expression of Trib3 1 0.00 2 1.38
22 INT158079 Binding of Esr1 and Gper 1 0.31 0.97 1.35
23 INT222182 Binding of ESR1 and HLA-DRB2 1 0.00 3.1 1.35
24 INT150890 Binding of Esr1 and Esr2 2 0.52 2.06 1.31
25 INT89878 Pdyn Positive_regulation of Gene_expression of Nkx2-5 1 0.35 0 1.29
26 INT89873 Pdyn Positive_regulation of Gene_expression of Gata4 1 0.23 0 1.29
27 INT114929 Positive_regulation of Binding of Oprm1 and Crebbp 1 0.06 0.14 1.28
28 INT89876 Pdyn Positive_regulation of Gata4 1 0.23 0 1.28
29 INT114925 Binding of Oprm1 and Crebbp 1 0.06 0.14 1.27
30 INT118784 Thop1 Positive_regulation of Protein_catabolism of Pax3 1 0.07 0.07 1.25
31 INT167278 Binding of OPRM1 and REST 1 0.08 0.94 1.24
32 INT351715 Pax3 Negative_regulation of Adarb1 1 0.00 0 1.19
33 INT55162 Binding of NFKB1 and RELA 10 0.30 2.82 1.18
34 INT146879 CRX Regulation of NMS 2 0.02 1.86 1.17
35 INT131887 Nr3c1 Regulation of Gene_expression of Prkcg 1 0.01 0 1.17
36 INT189017 Binding of Pax3 and Lmna 1 0.14 0.42 1.16
37 INT65373 Notch1 Regulation of Oprd1 1 0.09 0 1.16
38 INT200312 Rest Regulation of Oprm1 1 0.23 0.27 1.16
39 INT48809 Pax3 Negative_regulation of Binding of Tac1 1 0.22 0 1.16
40 INT314206 Mapk14 Positive_regulation of Pax3 1 0.08 0.67 1.15
41 INT242625 Gdnf Positive_regulation of Pax3 1 0.01 0.34 1.15
42 INT147447 ADCYAP1 Regulation of Localization of RELA 1 0.50 1.12 1.15
43 INT294911 Pax3 Positive_regulation of Il6 1 0.06 1.78 1.14
44 INT160540 Binding of NGF and PSIP1 2 0.29 1.43 1.12
45 INT100564 CRX Positive_regulation of Fos 1 0.04 0.89 1.06
46 INT133075 TFAM Positive_regulation of Transcription of OPRM1 1 0.03 0 1.04
47 INT200307 Rest Negative_regulation of Rorb 1 0.00 0.1 1.03
48 INT117908 Em Regulation of Localization of Pax3 1 0.00 0.07 1.03
49 INT160541 Binding of BDNF and PSIP1 4 0.49 1.94 1.02
50 INT49164 Binding of Pax3 and Nka1 1 0.01 0.37 1.01
51 INT49162 Nka1 Negative_regulation of Binding of Pax3 1 0.02 0.37 1.01
52 INT83987 Ngf Regulation of Atf2 1 0.52 0.49 1
53 INT170449 Pax3 Positive_regulation of Spr 1 0.01 0.26 0.99
54 INT200323 Binding of Oprm1 and Sp3 1 0.39 0 0.99
55 INT49163 Binding of Pax3 and Calca 1 0.03 0.37 0.98
56 INT4916 Binding of Pax3 and Wdyhv1 1 0.00 0 0.98
57 INT278292 Binding of CRP and ESR1 6 0.09 10.92 0.96
58 INT73461 PTPLA Positive_regulation of Transcription of TP53 1 0.06 0.99 0.96
59 INT29366 Mnt Positive_regulation of Localization of Penk 1 0.01 0 0.96
60 INT256357 Phosphorylation of Rela Positive_regulation of Localization of Ik 1 0.00 0.05 0.96
61 INT107951 Pax3 Positive_regulation of Tac1 1 0.11 1.21 0.95
62 INT330629 TP53 Negative_regulation of Gene_expression of Fos 1 0.30 1.76 0.94
63 INT196591 Binding of Lpar1 and Pax3 1 0.05 1.1 0.92
64 INT6975 Zeb1 Positive_regulation of St8sia1 1 0.03 0.17 0.91
65 INT334529 Pax3 Positive_regulation of Gene_expression of Ngf 1 0.03 0.31 0.91
66 INT341371 CRX Positive_regulation of Gene_expression of Ephb1 1 0.02 0.99 0.9
67 INT341370 CRX Positive_regulation of Gene_expression of Ceacam3 1 0.04 0.99 0.9
68 INT101259 Gata6 Negative_regulation of Gene_expression of ALOX15 1 0.42 0.67 0.89
69 INT14626 Binding of Dpep1 and Pax3 1 0.01 0 0.87
70 INT185329 Pax3 Positive_regulation of Gene_expression of Tg(CAG-EGFP)D4Nagy 1 0.00 0.22 0.87
71 INT200308 Binding of Rest and Rorb 1 0.00 0 0.87
72 INT101258 Gene_expression of Gata6 Negative_regulation of Positive_regulation of ALOX15 1 0.42 0.65 0.87
73 INT213977 Pax3 Negative_regulation of Gene_expression of Il2 1 0.00 0.25 0.86
74 INT330630 Binding of TP53 and Car1 1 0.23 1.56 0.86
75 INT140985 Gli3 Regulation of Ihh 1 0.29 0.85 0.85
76 INT97057 Bcl2l1 Regulation of Gene_expression of Trp53 1 0.36 0.51 0.83
77 INT97058 Cpz Regulation of Gene_expression of Trp53 1 0.27 0.57 0.83
78 INT278690 LEF1 Negative_regulation of Gene_expression of IK 1 0.00 0.66 0.83
79 INT65807 Nr3c1 Positive_regulation of Cyp3a23/3a1 1 0.14 0 0.82
80 INT189018 Nka1 Regulation of Pax3 1 0.01 0.1 0.81
81 INT341367 CRX Positive_regulation of Positive_regulation of FOS 1 0.04 0.83 0.8
82 INT104831 Binding of GLI2 and NFKB1 1 0.08 0 0.8
83 INT56499 Neurod1 Positive_regulation of Maoa 1 0.47 0 0.8
84 INT278697 LEF1 Negative_regulation of STAT6 1 0.00 0.44 0.78
85 INT108812 Esr1 Positive_regulation of Positive_regulation of Oprm1 1 0.42 0.38 0.78
86 INT258798 Binding of NR3C1 and HSP90AA1 1 0.01 1.09 0.78
87 INT110130 NR3C1 Regulation of ADORA1 1 0.04 0.73 0.77
88 INT64067 Tp63 Negative_regulation of Localization of Gh1 1 0.08 0.07 0.76
89 INT144547 Binding of Mecp2 and Sin3a 1 0.40 0.87 0.76
90 INT262563 Negative_regulation of Pax3 Regulation of Calca 1 0.01 0.75 0.76
91 INT158068 Positive_regulation of Pparg Positive_regulation of Positive_regulation of PTGS2 1 0.01 0.28 0.76
92 INT294908 Pax3 Positive_regulation of Gene_expression of Il1 1 0.03 0.45 0.76
93 INT262569 Pax3 Regulation of Calca 1 0.00 0.75 0.76
94 INT111194 Binding of NEUROD1 and Pck1 1 0.39 0 0.75
95 INT137699 AR Regulation of PDYN 1 0.46 0.93 0.75
96 INT314203 Nos2 Positive_regulation of Gli3 1 0.19 1.27 0.73
97 INT228494 Binding of Ncoa5 and Rela 1 0.00 1.58 0.72
98 INT294906 Binding of Pax3 and Tac4 1 0.01 1.15 0.71
99 INT153123 NFKBIA Negative_regulation of Phosphorylation of RELA 1 0.03 2.01 0.71
100 INT306263 Binding of NFIB and TFAM 1 0.00 1.74 0.7
101 INT142994 Binding of UPF1 and FCMTE1 1 0.00 0.91 0.7
102 INT98951 Positive_regulation of Binding of NR5A2 and SP3 1 0.00 0 0.7
103 INT98957 Binding of NR5A2 and SP3 1 0.00 0 0.7
104 INT40134 Binding of Pomc and Noc2l 1 0.01 0.08 0.7
105 INT207540 Tfap2a Regulation of Oprm1 1 0.13 0.06 0.7
106 INT320634 Positive_regulation of MAPK1 Regulation of PBX2 1 0.03 1.21 0.7
107 INT82497 Binding of CRX and Nts 1 0.05 1.54 0.7
108 INT64070 Tp63 Regulation of Ghrh 1 0.04 0.06 0.69
109 INT135207 Gmeb1 Regulation of Gene_expression of Tfap2a 1 0.07 0.48 0.69
110 INT64068 Tp63 Regulation of Fdft1 1 0.00 0.06 0.69
111 INT135206 Ighen Regulation of Gene_expression of Tfap2a 1 0.06 0.48 0.69
112 INT135202 Tfap2a Regulation of Gene_expression of Ighen 1 0.06 0.48 0.69
113 INT135213 Tfap2a Regulation of Gene_expression of Nfkb1 1 0.02 0.48 0.69
114 INT135211 Nfkb1 Regulation of Gene_expression of Tfap2a 1 0.02 0.48 0.69
115 INT135204 Tfap2a Regulation of Gene_expression of Gmeb1 1 0.10 0.48 0.69
116 INT81769 Binding of Chrna4 and Neurod1 1 0.35 0.07 0.69
117 INT222181 TFAM Positive_regulation of XCR1 1 0.00 1.89 0.68
118 INT68561 Binding of Gli3 and Ust 1 0.01 0.68 0.68
119 INT222211 TFAM Positive_regulation of Ccr1 1 0.02 1.89 0.68
120 INT213971 Mthfd1 Positive_regulation of Gene_expression of Pax3 1 0.00 0.14 0.68
121 INT207543 Tfap2a Regulation of Qsox1 1 0.04 0.06 0.67
122 INT262570 Binding of Pax3 and Trpv1 1 0.02 1.05 0.67
123 INT152925 Aanat Positive_regulation of Nanog 1 0.02 0.42 0.67
124 INT101986 TP53 Positive_regulation of Gene_expression of GDF15 1 0.52 2.45 0.67
125 INT298728 Akt1 Positive_regulation of Rela 1 0.01 1.03 0.67
126 INT335456 Binding of PDX1 and hb 1 0.02 2.59 0.66
127 INT110458 Binding of Atf2 and Mapk8 1 0.35 0 0.66
128 INT224823 CTBS Regulation of SALL1 1 0.14 0.53 0.66
129 INT38057 Binding of Crp and Esr1 2 0.04 1.21 0.65
130 INT135361 Prr14 Positive_regulation of Mecp2 1 0.24 0.15 0.64
131 INT200317 Rest Negative_regulation of Transcription of Oprm1 1 0.31 0 0.64
132 INT135363 Mecp2 Positive_regulation of Mbd1 1 0.50 0.15 0.64
133 INT89877 Pdyn Positive_regulation of Nkx2-5 1 0.11 0 0.64
134 INT154263 NEUROD1 Positive_regulation of Gene_expression of GAL 1 0.50 0.06 0.63
135 INT114948 NCOA1 Positive_regulation of Positive_regulation of PPARA 1 0.20 0.24 0.62
136 INT98955 Positive_regulation of Binding of SP3 and CFHR4 1 0.00 0 0.62
137 INT114949 NCOA1 Positive_regulation of Gene_expression of RXRA 1 0.13 0.24 0.61
138 INT166402 CDKN1A Regulation of Gene_expression of TP53 1 0.27 0.83 0.61
139 INT309158 Binding of Esr1 and Dlat 1 0.04 1.39 0.61
140 INT98952 Binding of SP3 and CFHR4 1 0.00 0 0.61
141 INT52820 Oprd1 Regulation of NR3C1 1 0.02 0.17 0.61
142 INT170446 Pax3 Positive_regulation of Gene_expression of Spr 1 0.01 0 0.58
143 INT109065 Pdyn Positive_regulation of Gene_expression of Gata4 1 0.00 0 0.58
144 INT223928 Cux1 Regulation of Gene_expression of Maoa 1 0.24 0.15 0.57
145 INT145431 Pax3 Positive_regulation of Positive_regulation of Ros1 1 0.02 0.07 0.57
146 INT804 Aap Negative_regulation of MBD2 1 0.01 0 0.57
147 INT185809 Binding of PDX1 and SPP1 1 0.02 1.69 0.57
148 INT223924 Cux1 Regulation of Gene_expression of Serpina1 1 0.04 0.15 0.57
149 INT341594 Binding of ESR1 and HLA-B 1 0.01 0.72 0.57
150 INT141362 EP300 Negative_regulation of Transcription of IL2 1 0.17 0 0.56
151 INT73920 Binding of CCNT1 and CYP2B6 1 0.19 0.17 0.56
152 INT200348 Sp3 Negative_regulation of Gene_expression of Oprm1 1 0.48 0.4 0.55
153 INT167651 Binding of Oprd1 and Ep300 1 0.02 0.09 0.55
154 INT343913 Binding of FOS and Smad3 1 0.19 0.92 0.54
155 INT223934 HSPG2 Negative_regulation of Gene_expression of Cux1 1 0.03 0 0.53
156 INT119745 NEUROD1 Regulation of Gene_expression of BHLHE22 1 0.11 0.26 0.53
157 INT247265 Mecp2 Regulation of Fos 1 0.25 0.38 0.52
158 INT254200 Mif Regulation of Trp53 1 0.02 0.96 0.52
159 INT146880 CRX Positive_regulation of Ngf 1 0.03 0.78 0.52
160 INT95042 Binding of NEUROD1 and Olr1246 1 0.02 0.23 0.51
161 INT167652 Binding of Ep300 and Ngf 1 0.09 0.06 0.51
162 INT167655 Binding of Polr2f and Ep300 1 0.01 0.06 0.51
163 INT150833 Esr1 Positive_regulation of Localization of Prkce 1 0.08 0.29 0.51
164 INT135360 Binding of Mecp2 and Aadac 1 0.03 0.19 0.51
165 INT278105 Negative_regulation of TP63 Negative_regulation of Binding of P2RX7 1 0.00 0 0.51
166 INT271344 MPO Regulation of Protein_catabolism of ACCS 1 0.02 2.42 0.51
167 INT291556 Binding of ESR1 and Sec22b 2 0.00 0.86 0.5
168 INT157709 CRX Positive_regulation of Mpo 1 0.08 1.11 0.5
169 INT154014 Binding of Esr1 and Gabrg1 1 0.07 0.07 0.5
170 INT162499 Binding of AHR and NEUROD1 3 0.25 0.19 0.49
171 INT14992 FPR1 Positive_regulation of Localization of MPO 2 0.56 1.1 0.49
172 INT244028 Positive_regulation of Binding of Cacnb3 and Tfap2a 1 0.01 0.24 0.49
173 INT244037 Positive_regulation of Binding of Prkaca and Tfap2a 1 0.01 0.24 0.49
174 INT132242 NR3C1 Regulation of Gene_expression of Slc1a1 1 0.09 0.62 0.49
175 INT184405 CRP Positive_regulation of Gene_expression of ASF1A 1 0.03 1.17 0.49
176 INT200321 Binding of Rest and Negative_regulation of Gene_expression of Oprm1 1 0.36 0.05 0.49
177 INT244000 Positive_regulation of Binding of Tfap2a and Dnm1 1 0.04 0.24 0.49
178 INT156155 Binding of HCFC1 and TFAM 1 0.04 0.74 0.49
179 INT244035 Binding of Prkaca and Tfap2a 1 0.01 0.24 0.49
180 INT65185 Binding of ATRX and Ssr1 1 0.03 1.68 0.49
181 INT274371 Phc1 Regulation of Gene_expression of Cfp 1 0.03 0.47 0.49
182 INT126336 Negative_regulation of Binding of Pax3 and Tac1 1 0.01 0.66 0.49
183 INT243997 Binding of Tfap2a and Dnm1 1 0.03 0.24 0.49
184 INT244060 Binding of Cacnb3 and Tfap2a 1 0.00 0.24 0.49
185 INT352031 Binding of NR3C1 and JUND 1 0.10 2.87 0.48
186 INT165078 Binding of CTSB and Notch1 1 0.00 1.08 0.48
187 INT319718 Binding of Crebbp and Creb1 1 0.10 1.68 0.48
188 INT58578 Binding of RPA1 and TACR1 1 0.01 0 0.48
189 INT141729 NR3C1 Regulation of Positive_regulation of Cnr1 1 0.06 0.7 0.47
190 INT173475 Bcar1 Regulation of Isl1 1 0.01 0 0.47
191 INT185917 Binding of AR and MAPK1 1 0.07 0.5 0.47
192 INT125568 Binding of Casr and Ncoa6 3 0.50 1.13 0.46
193 INT142826 UPF1 Positive_regulation of CREB1 1 0.11 0 0.46
194 INT288265 Binding of FLG and NEUROG1 1 0.02 1.06 0.46
195 INT147179 Esr1 Regulation of Gene_expression of Penk 1 0.01 0.68 0.46
196 INT223936 HSPG2 Positive_regulation of Gene_expression of Cux1 1 0.03 0 0.46
197 INT195552 Binding of Rela and Ep300 1 0.03 0.2 0.45
198 INT223935 HSPG2 Positive_regulation of Cux1 1 0.03 0 0.45
199 INT195554 Binding of Nfkb1 and Ep300 1 0.08 0.2 0.45
200 INT335850 Snrpc Negative_regulation of Gene_expression of Isl1 1 0.00 1.51 0.45

Single Events

The table below shows the top 100 pain related interactions that have been reported for chromatin binding. They are ordered first by their pain relevance and then by number of times they were reported in chromatin binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT8534 Localization of Pax3 85 0.59 28.71 82.82
2 INT14624 Gene_expression of Pax3 100 0.38 33.22 69.47
3 INT5374 Gene_expression of Esr1 412 0.77 263.89 67.34
4 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64
5 INT3361 Positive_regulation of Esr1 273 0.69 208.53 44.81
6 INT4913 Binding of Pax3 52 0.28 9.57 42.67
7 INT9082 Positive_regulation of ESR1 238 0.69 148.51 36.69
8 INT67613 Positive_regulation of PPARG 94 0.70 69.15 34.38
9 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8
10 INT6584 Negative_regulation of Pax3 31 0.39 14.64 27.97
11 INT37296 Binding of Esr1 117 0.43 62.51 27.33
12 INT5206 Gene_expression of AR 316 0.78 113.83 27.29
13 INT20462 Binding of ESR1 210 0.44 102.7 26.34
14 INT28336 Positive_regulation of Pax3 37 0.33 20.94 25.66
15 INT67610 Positive_regulation of Pparg 53 0.70 31.91 25.2
16 INT823 Negative_regulation of ESR1 144 0.58 63.72 22.52
17 INT73625 Gene_expression of PPARG 108 0.78 104.85 21.42
18 INT85952 Positive_regulation of AR 168 0.67 64.36 20.66
19 INT67608 Gene_expression of Pparg 41 0.78 25.09 19.53
20 INT101188 Gene_expression of Rela 81 0.56 23.43 19.15
21 INT171060 Gene_expression of PDX1 72 0.75 72.57 17.97
22 INT4067 Negative_regulation of Esr1 97 0.50 43.45 17.52
23 INT70557 Negative_regulation of Localization of Pax3 1 0.36 1.15 17.32
24 INT17237 Regulation of Esr1 74 0.43 49.09 17.25
25 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71
26 INT93361 Gene_expression of Trp53 208 0.78 175.35 16.65
27 INT80972 Gene_expression of Tp53 104 0.78 102.74 16.02
28 INT92354 Localization of ESR1 77 0.75 33.04 15.51
29 INT73916 Gene_expression of Esr1 58 0.77 26.59 15.15
30 INT93482 Localization of Rela 56 0.78 24.52 14.82
31 INT5904 Localization of MPO 62 0.81 36.37 14.64
32 INT2038 Localization of Esr1 104 0.79 40.12 13.27
33 INT67611 Positive_regulation of Pparg 39 0.69 18.33 13.23
34 INT144646 Positive_regulation of Rela 53 0.67 27.78 13.2
35 INT35097 Gene_expression of Cux1 6 0.58 3.86 12.83
36 INT13409 Gene_expression of NEUROD1 52 0.75 14.17 12.23
37 INT79545 Positive_regulation of Gene_expression of ESR1 82 0.64 39.42 12.18
38 INT70556 Positive_regulation of Localization of Pax3 9 0.34 3.13 12.11
39 INT121223 Positive_regulation of Gene_expression of Pax3 17 0.16 4.52 12.06
40 INT70555 Regulation of Pax3 13 0.35 3.62 12.05
41 INT16772 Gene_expression of MPO 81 0.78 90.98 11.9
42 INT111476 Gene_expression of TP63 88 0.76 61.08 11.64
43 INT152 Negative_regulation of MBD2 31 0.38 3.95 11.31
44 INT171253 Positive_regulation of BMI1 23 0.53 39.41 11.23
45 INT79685 Positive_regulation of Gene_expression of Pparg 17 0.70 14.63 11.03
46 INT79656 Positive_regulation of NR3C1 14 0.68 6.38 10.83
47 INT91774 Gene_expression of Nr3c1 27 0.78 16.14 10.7
48 INT108917 Positive_regulation of CRX 23 0.50 21.32 10.5
49 INT73223 Gene_expression of UPF1 78 0.41 31.44 9.94
50 INT169997 Positive_regulation of Gene_expression of Tp53 37 0.70 47.3 9.85
51 INT29988 Gene_expression of Mecp2 27 0.78 5.45 9.47
52 INT149138 Binding of PDX1 27 0.37 32.62 9.33
53 INT155944 Gene_expression of Foxp3 66 0.66 24.37 9.12
54 INT152668 Negative_regulation of EP300 13 0.38 7.78 9.03
55 INT67612 Binding of PPARG 38 0.48 22.67 8.94
56 INT35366 Binding of AR 87 0.47 30.52 8.9
57 INT6019 Positive_regulation of NEUROD1 37 0.67 17.3 8.89
58 INT66213 Localization of RELA 63 0.78 14.71 8.77
59 INT26751 Regulation of Nr3c1 13 0.61 6.58 8.65
60 INT50767 Positive_regulation of Nanog 14 0.67 3.63 8.56
61 INT169015 Gene_expression of FOXP3 50 0.60 33.18 8.4
62 INT56223 Positive_regulation of MPO 35 0.70 43 8.2
63 INT61363 Positive_regulation of TFAM 43 0.69 26.43 8.14
64 INT165228 Binding of BMI1 13 0.47 25.36 7.97
65 INT15687 Regulation of ESR1 91 0.60 40.42 7.95
66 INT28358 Gene_expression of Nanog 25 0.70 3.52 7.85
67 INT101414 Gene_expression of Phc1 27 0.60 9.55 7.58
68 INT66318 Gene_expression of NR3C1 26 0.76 20 7.55
69 INT57748 Positive_regulation of Gene_expression of TP53 85 0.69 79.55 7.49
70 INT113 Positive_regulation of MBD2 33 0.49 6.76 7.49
71 INT49749 Negative_regulation of Nr3c1 13 0.43 6.25 7.36
72 INT103399 Positive_regulation of Positive_regulation of Pparg 11 0.66 7 7.36
73 INT97055 Positive_regulation of Gene_expression of Trp53 51 0.70 45.7 7.25
74 INT90715 Gene_expression of Egr2 12 0.73 1.64 7.17
75 INT18340 Gene_expression of CRX 16 0.22 13.85 7.13
76 INT43063 Positive_regulation of Cux1 3 0.49 1.57 7.13
77 INT64370 Gene_expression of Neurod1 22 0.75 5.19 7.1
78 INT16722 Negative_regulation of MPO 25 0.59 18.55 6.99
79 INT118782 Protein_catabolism of Pax3 7 0.94 0.46 6.95
80 INT110987 Transcription of ESR1 45 0.71 24.16 6.72
81 INT50387 Negative_regulation of AR 67 0.45 26.31 6.61
82 INT256345 Phosphorylation of Rela 21 0.75 9.51 6.56
83 INT185879 Gene_expression of CDC6 9 0.39 5.18 6.46
84 INT22901 Negative_regulation of Gene_expression of Esr1 30 0.42 20.92 6.29
85 INT7564 Positive_regulation of Nr3c1 16 0.68 4.98 6.25
86 INT93359 Positive_regulation of Trp53 90 0.70 69.77 6.24
87 INT6097 Negative_regulation of NEUROD1 30 0.57 9.71 6.24
88 INT185252 Gene_expression of Dlx2 7 0.71 8.8 6.24
89 INT144539 Phosphorylation of Mecp2 3 0.82 6.18 6.2
90 INT4911 Negative_regulation of Binding of Pax3 7 0.22 1.89 6.17
91 INT67609 Binding of Pparg 17 0.46 9.53 6.06
92 INT135359 Positive_regulation of Mecp2 4 0.70 4.35 6.05
93 INT38686 Binding of NR3C1 20 0.48 9.25 5.99
94 INT6098 Binding of NEUROD1 17 0.47 3.4 5.99
95 INT112545 Phosphorylation of TP53 28 0.80 14.13 5.93
96 INT100078 Positive_regulation of Positive_regulation of PPARG 11 0.70 3.6 5.86
97 INT52819 Negative_regulation of NR3C1 14 0.50 7.22 5.84
98 INT20280 Positive_regulation of Esr1 32 0.69 18.37 5.69
99 INT88286 Phosphorylation of Atf2 11 0.66 1.93 5.69
100 INT115370 Gene_expression of PSIP1 22 0.65 9.45 5.68
101 INT123726 Positive_regulation of Notch1 23 0.70 7.2 5.65
102 INT43997 Positive_regulation of Gene_expression of Esr1 57 0.51 36.66 5.51
103 INT5903 Negative_regulation of Localization of MPO 10 0.59 5.71 5.45
104 INT48840 Gene_expression of Nkx2-2 8 0.23 1.55 5.44
105 INT52814 Negative_regulation of Nr3c1 9 0.57 5.69 5.41
106 INT77252 Gene_expression of Nr3c1 17 0.67 9.71 5.38
107 INT127112 Phosphorylation of Smad2 19 0.80 11.01 5.36
108 INT97693 Gene_expression of REST 29 0.75 5.51 5.26
109 INT60585 Regulation of TP53 59 0.59 54.55 5.21
110 INT99091 Regulation of AR 70 0.45 31.68 5.05
111 INT68559 Negative_regulation of Gli3 5 0.37 4.56 4.93
112 INT88282 Positive_regulation of Phosphorylation of Atf2 8 0.44 1.77 4.85
113 INT16621 Negative_regulation of Esr1 20 0.54 8.2 4.84
114 INT109972 Phosphorylation of Trp53 13 0.80 6.15 4.68
115 INT203443 Gene_expression of Isl1 27 0.67 11.12 4.65
116 INT5205 Localization of AR 43 0.80 12.87 4.63
117 INT84727 Negative_regulation of Gene_expression of AR 38 0.58 12.46 4.63
118 INT62684 Negative_regulation of TP53 66 0.58 66.09 4.62
119 INT133630 Negative_regulation of Gene_expression of ESR1 42 0.52 23.89 4.57
120 INT52818 Localization of NR3C1 13 0.69 7.65 4.57
121 INT2213 Regulation of EP300 10 0.54 4.72 4.5
122 INT55171 Gene_expression of RELA 80 0.75 17.17 4.47
123 INT57749 Negative_regulation of Gene_expression of TP53 39 0.56 36.79 4.45
124 INT198736 Binding of Sp3 23 0.40 4.77 4.42
125 INT69217 Gene_expression of Notch1 20 0.78 7.8 4.41
126 INT73626 Positive_regulation of Gene_expression of PPARG 22 0.70 18.82 4.4
127 INT94277 Positive_regulation of Gene_expression of Egr2 7 0.49 0.69 4.4
128 INT79692 Negative_regulation of PPARG 24 0.59 16 4.31
129 INT125282 Negative_regulation of Positive_regulation of NR3C1 3 0.57 0.54 4.31
130 INT36674 Negative_regulation of Phc1 11 0.37 2.71 4.22
131 INT15257 Positive_regulation of Nkx2-2 10 0.21 1.75 4.2
132 INT93483 Negative_regulation of Localization of Rela 11 0.57 5.1 4.19
133 INT117205 Transcription of Esr1 23 0.65 9.4 4.14
134 INT51180 Regulation of Nkx2-2 5 0.26 2.16 4.14
135 INT171252 Gene_expression of BMI1 21 0.70 26.98 4.11
136 INT158377 Positive_regulation of Positive_regulation of Rela 6 0.49 3.08 4.11
137 INT49712 Regulation of Nr3c1 10 0.28 5.65 4.06
138 INT72936 Gene_expression of Pparg 39 0.77 19.01 4.02
139 INT64170 Gene_expression of GLI2 31 0.46 14.96 3.99
140 INT59836 Positive_regulation of Upf1 24 0.02 4.42 3.99
141 INT112070 Negative_regulation of Gene_expression of Pparg 6 0.59 3.72 3.96
142 INT41878 Positive_regulation of EP300 13 0.61 5.24 3.95
143 INT57724 Regulation of Cux1 10 0.39 1.81 3.92
144 INT217102 Gene_expression of Egr2 50 0.78 10.91 3.89
145 INT94303 Gene_expression of Upf1 44 0.04 11.62 3.87
146 INT199692 Gene_expression of Mkrn1 48 0.75 15.2 3.84
147 INT8600 Binding of Nkx2-2 6 0.10 0.87 3.82
148 INT218955 Protein_catabolism of ESR1 9 0.92 3.95 3.74
149 INT133550 Negative_regulation of Gene_expression of Rela 14 0.40 4.64 3.73
150 INT200248 Gene_expression of Rest 1 0.66 1.25 3.7
151 INT71602 Negative_regulation of Trp53 84 0.59 67.77 3.68
152 INT20461 Binding of Esr1 34 0.48 9.58 3.66
153 INT76815 Regulation of Gene_expression of Pax3 4 0.12 3.81 3.65
154 INT82846 Negative_regulation of CRX 9 0.37 5.93 3.64
155 INT77251 Positive_regulation of Atf2 8 0.70 2.45 3.62
156 INT14319 Localization of SHMT2 3 0.03 1.91 3.61
157 INT195527 Binding of Rela 17 0.25 4.42 3.56
158 INT318967 Gene_expression of Mecp2 9 0.77 11.52 3.55
159 INT67726 Gene_expression of Notch1 36 0.75 9.77 3.54
160 INT5204 Positive_regulation of Gene_expression of AR 60 0.67 23.54 3.53
161 INT78845 Binding of Pparg 16 0.44 11.67 3.53
162 INT20011 Regulation of NEUROD1 10 0.44 3.83 3.53
163 INT76625 Positive_regulation of Phc1 14 0.36 5.1 3.49
164 INT64825 Negative_regulation of Nanog 8 0.57 2.59 3.47
165 INT131165 Positive_regulation of Gene_expression of Nr3c1 8 0.70 7.18 3.44
166 INT73557 Positive_regulation of RELA 57 0.46 8.7 3.43
167 INT170438 Negative_regulation of Gene_expression of Pax3 4 0.04 1.03 3.42
168 INT12844 Binding of TP63 15 0.47 10.57 3.38
169 INT14994 Positive_regulation of Localization of MPO 12 0.70 6.85 3.37
170 INT178631 Phosphorylation of ESR1 21 0.75 9.16 3.36
171 INT133214 Regulation of PDX1 9 0.34 10.26 3.36
172 INT19903 Negative_regulation of Cux1 7 0.57 2.8 3.33
173 INT24983 Binding of MPO 18 0.42 17.56 3.29
174 INT133557 Transcription of Rela 6 0.52 3.86 3.2
175 INT148190 Positive_regulation of Transcription of Nanog 1 0.49 0.2 3.17
176 INT72618 Regulation of Tcf3 5 0.44 1.48 3.16
177 INT73918 Transcription of Esr1 21 0.66 8.74 3.12
178 INT110956 Negative_regulation of Positive_regulation of Pparg 5 0.41 3.68 3.11
179 INT66212 Negative_regulation of Localization of RELA 13 0.57 2.48 3.09
180 INT165811 Binding of Phc1 13 0.15 5.99 3.09
181 INT112071 Regulation of Gene_expression of Pparg 4 0.62 4.62 3.09
182 INT138319 Positive_regulation of Rpa1 3 0.07 2.75 3.07
183 INT40128 Binding of Noc2l 7 0.27 0.67 3.03
184 INT3869 Gene_expression of SHMT2 7 0.37 3.6 3.03
185 INT82719 Positive_regulation of ASF1A 2 0.08 9.55 3
186 INT99187 Negative_regulation of Positive_regulation of PPARG 5 0.42 5.07 2.99
187 INT8103 Binding of TP53 46 0.44 40.2 2.96
188 INT199255 Binding of Rest 14 0.41 1.43 2.94
189 INT101567 Gene_expression of Ctnnb1 7 0.64 10.11 2.89
190 INT39856 Binding of Neurod1 8 0.47 1.44 2.88
191 INT31541 Regulation of Esr1 15 0.54 4.12 2.82
192 INT139872 Regulation of Notch1 14 0.45 7.69 2.82
193 INT122787 Transcription of Nanog 4 0.67 0.78 2.81
194 INT122782 Negative_regulation of Positive_regulation of Nanog 3 0.57 1.15 2.81
195 INT130705 Gene_expression of TFAM 50 0.77 38.85 2.79
196 INT153221 Positive_regulation of Rela 5 0.16 2.16 2.72
197 INT171058 Negative_regulation of PDX1 5 0.32 9.31 2.72
198 INT13703 Regulation of Phc1 7 0.23 3.92 2.71
199 INT174727 Positive_regulation of Positive_regulation of ESR1 14 0.44 6.3 2.7
200 INT58720 Negative_regulation of SAFB 4 0.50 0.19 2.69
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