GO:0003690

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Name double-stranded DNA binding
Categary Function
Go Slim No
Go Link GO:0003690
Unique Molecular Interactions 2099
Total Molecular Interactions 2879
Total Single Events 28922
Pain Genes Associated 148

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for double-stranded DNA binding. They are ordered first by their pain relevance and then by number of times they were reported for double-stranded DNA binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT11250 Cck Positive_regulation of Gene_expression of Fos 14 0.78 0.08 7.29
2 INT169218 Binding of EGFR and Coc 1 0.06 2.8 5.85
3 INT186566 Hpcl1 Positive_regulation of Fos 1 0.17 0.38 4.49
4 INT200322 Binding of Rest and Sp3 1 0.39 2.93 3.98
5 INT113080 Drd1a Positive_regulation of Phosphorylation of Creb1 2 0.27 0.43 3.88
6 INT220623 Binding of Stat1 and Bace1 11 0.25 10.33 3.81
7 INT11252 Cck Positive_regulation of Fos 6 0.78 0 3.79
8 INT115690 Negative_regulation of Prkcg Negative_regulation of Gene_expression of Fos 1 0.47 0.72 3.63
9 INT17317 Binding of Jun and Fos 7 0.42 1.03 3.5
10 INT161164 Prkcg Regulation of Phosphorylation of Creb1 3 0.41 0.62 3.11
11 INT309150 Edc4 Positive_regulation of Creb1 1 0.03 3.46 3.09
12 INT190167 Binding of JUN and MMP12 1 0.26 0.82 2.76
13 INT127621 Bst1 Regulation of Positive_regulation of Fos 1 0.26 0 2.73
14 INT54489 Binding of Jun and Rabep2 4 0.16 1.48 2.3
15 INT156622 Umod Regulation of Phosphorylation of Creb1 1 0.05 0.33 2.27
16 INT146520 Tmem132a Regulation of Gene_expression of Fos 1 0.69 0.5 2.18
17 INT184262 Binding of AGER and HMGB1 1 0.34 4.49 2.17
18 INT158964 FosB Negative_regulation of Creb1 1 0.21 0 2.07
19 INT114927 Positive_regulation of Binding of Oprm1 and Creb1 1 0.17 0.28 2.07
20 INT190524 Ros1 Positive_regulation of Nfkb1 3 0.02 4.24 2.06
21 INT114923 Binding of Oprm1 and Creb1 1 0.16 0.28 2.06
22 INT88883 IRF6 Positive_regulation of Nfkb1 1 0.11 0.53 2.01
23 INT124133 Camk2a Regulation of Phosphorylation of Creb1 1 0.46 0 2
24 INT117794 Hpcl1 Positive_regulation of Gene_expression of Fos 3 0.17 0.15 1.98
25 INT54488 Npepo Regulation of Gene_expression of Jun 1 0.30 0 1.98
26 INT125348 Decr1 Regulation of Gene_expression of Fos 1 0.00 0.1 1.92
27 INT186435 Prkcg Regulation of Creb1 1 0.44 0.45 1.9
28 INT186432 Prkaca Regulation of Creb1 1 0.14 0.45 1.9
29 INT338691 Binding of Trpv1 and Aff3 1 0.24 1.21 1.88
30 INT50993 Il1b Positive_regulation of Fos 2 0.40 0.43 1.84
31 INT155460 Tnfrsf1a Positive_regulation of Positive_regulation of Nfkb1 1 0.42 2.39 1.82
32 INT112526 D2Mit212 Negative_regulation of Gene_expression of Fos 1 0.03 0.28 1.8
33 INT146512 Tmem132a Negative_regulation of Gene_expression of Fos 1 0.23 0 1.76
34 INT139640 Jun Regulation of Gene_expression of Npy 1 0.21 1.98 1.75
35 INT94203 SP5 Positive_regulation of FOS 1 0.25 1.41 1.72
36 INT137207 Tnf Positive_regulation of Nfkb1 3 0.23 2.69 1.71
37 INT186433 Trib3 Regulation of Phosphorylation of Creb1 1 0.03 0.32 1.71
38 INT215100 Binding of Hmgb1 and Tlr4 5 0.29 3.21 1.68
39 INT160304 Npy Regulation of Gene_expression of Fos 3 0.67 1.43 1.68
40 INT54484 Npepo Positive_regulation of Gene_expression of Fos 1 0.43 0 1.63
41 INT155459 Tnfrsf1a Positive_regulation of Nfkb1 1 0.42 2.45 1.63
42 INT215096 Binding of Hmgb1 and Tlr2 9 0.38 11.61 1.61
43 INT105112 Plat Positive_regulation of JUN 1 0.01 1.55 1.58
44 INT131574 Negative_regulation of Ephb1 Negative_regulation of Gene_expression of Creb1 1 0.41 0.33 1.58
45 INT212660 Nr3c1 Regulation of KCNA1 1 0.00 1.25 1.57
46 INT114926 Creb1 Negative_regulation of Positive_regulation of Oprm1 1 0.13 0.23 1.56
47 INT158877 PRS Positive_regulation of Gene_expression of Fos 1 0.09 5.14 1.54
48 INT79021 Regulation of Binding of Jun and Fos 2 0.50 0.66 1.5
49 INT121747 Prkcg Negative_regulation of Positive_regulation of Creb1 1 0.16 0.2 1.5
50 INT121741 Prkaca Negative_regulation of Positive_regulation of Creb1 1 0.10 0.2 1.49
51 INT73650 Binding of Pim3 and Creb1 1 0.03 2.48 1.47
52 INT72319 Adarb1 Positive_regulation of Gene_expression of Fos 3 0.10 0.1 1.44
53 INT157540 Binding of SP1 and YY1 1 0.41 2.55 1.42
54 INT68723 Pomgnt1 Negative_regulation of Gene_expression of Fos 1 0.12 0 1.41
55 INT108583 Binding of Vip and Fos 1 0.36 0 1.39
56 INT168724 Creb1 Negative_regulation of Gene_expression of Calca 1 0.46 1.09 1.38
57 INT167169 Nfkb1 Regulation of Gene_expression of Crp 1 0.09 1.76 1.38
58 INT168721 Positive_regulation of Creb1 Positive_regulation of Calca 1 0.53 1.07 1.37
59 INT106850 P2ry2 Positive_regulation of Phosphorylation of Creb1 2 0.49 0.73 1.36
60 INT168722 Creb1 Positive_regulation of Calca 1 0.73 1.05 1.35
61 INT94630 Positive_regulation of Adarb1 Positive_regulation of Gene_expression of Fos 2 0.03 0.1 1.32
62 INT120929 Prkcg Regulation of Gene_expression of Fos 2 0.50 0.34 1.31
63 INT131886 Creb1 Positive_regulation of Gene_expression of Prkcg 1 0.03 0 1.31
64 INT131256 Positive_regulation of Nfkb1 Positive_regulation of Gene_expression of Nfkbia 1 0.38 0.94 1.31
65 INT192080 Foxm1 Positive_regulation of Cnr1 2 0.14 0.72 1.3
66 INT148778 Binding of Usf1 and Rtn1 1 0.40 0.85 1.3
67 INT169297 TRPV1 Positive_regulation of EGFR 1 0.64 0.37 1.3
68 INT66428 Dcc Positive_regulation of Fos 2 0.05 0.39 1.29
69 INT148775 Binding of Calca and Usf1 1 0.43 0.85 1.29
70 INT121802 DEAF1 Negative_regulation of HTR1A 1 0.46 0.88 1.29
71 INT169289 CNR1 Positive_regulation of EGFR 1 0.62 0.36 1.28
72 INT70181 PRCP Positive_regulation of FOS 1 0.58 0.36 1.26
73 INT124767 Creb1 Regulation of Oprm1 1 0.45 0 1.26
74 INT114635 Hmox2 Positive_regulation of Gene_expression of Fos 1 0.47 0.88 1.26
75 INT352269 Binding of Jund and Adora1 1 0.15 1.2 1.25
76 INT136250 Phosphorylation of Tff3 Regulation of Creb1 1 0.02 0.18 1.24
77 INT141244 Fos Regulation of Prkaca 1 0.18 0.07 1.24
78 INT71443 CSAD Positive_regulation of Gene_expression of Fos 1 0.58 0.81 1.23
79 INT136256 Creb1 Regulation of SGCG 1 0.26 0.18 1.23
80 INT136258 Creb1 Regulation of GRIA1 1 0.26 0.18 1.23
81 INT131195 Creb1 Positive_regulation of Positive_regulation of Drd1a 2 0.27 0.61 1.22
82 INT256298 Binding of Creb1 and Ephb1 1 0.16 1.27 1.22
83 INT159837 Trim2 Negative_regulation of Transcription of Fos 1 0.10 1.92 1.22
84 INT109380 Binding of Adarb1 and Fos 1 0.02 0.38 1.19
85 INT256297 Binding of Creb1 and Insrr 1 0.00 1.22 1.19
86 INT256295 Binding of Creb1 and Grin2b 1 0.11 1.21 1.19
87 INT73075 Adarb1 Regulation of Fos 1 0.01 0.07 1.18
88 INT131887 Nr3c1 Regulation of Gene_expression of Prkcg 1 0.01 0 1.17
89 INT124435 Gene_expression of Chrna9 Positive_regulation of Phosphorylation of Creb1 1 0.11 0.6 1.17
90 INT150191 CEACAM3 Positive_regulation of Gene_expression of FOS 1 0.34 0.14 1.16
91 INT123454 CNR1 Regulation of Fos 1 0.00 0.06 1.12
92 INT130471 Prkcg Regulation of Regulation of Fos 1 0.45 0.27 1.12
93 INT112608 DNAJC15 Regulation of Gene_expression of Fos 1 0.02 0.14 1.12
94 INT123455 CNR1 Regulation of Positive_regulation of Fos 1 0.00 0.06 1.12
95 INT202620 Binding of Ppara and Rxra 15 0.09 2.63 1.11
96 INT143941 Il1f5 Negative_regulation of Gene_expression of Fos 1 0.00 1.03 1.11
97 INT102421 POMC Regulation of Gene_expression of Fos 1 0.12 0.34 1.11
98 INT229913 Positive_regulation of Ntsr1 Positive_regulation of Gene_expression of Egr1 1 0.12 1.33 1.11
99 INT105423 Jun Positive_regulation of Gene_expression of Penk 1 0.43 0 1.09
100 INT164382 MAPK3 Positive_regulation of Gene_expression of Fos 1 0.75 0.2 1.08
101 INT164383 Positive_regulation of MAPK3 Positive_regulation of Gene_expression of Fos 1 0.54 0.2 1.08
102 INT132701 Adarb1 Negative_regulation of Gene_expression of Fos 1 0.01 0.73 1.07
103 INT156462 Creb1 Regulation of Ephb1 1 0.29 0 1.07
104 INT114364 Hmgb1 Positive_regulation of Gene_expression of TNF 2 0.05 1.85 1.06
105 INT127437 deltaFosB Negative_regulation of Vta1 1 0.01 0.09 1.06
106 INT100564 CRX Positive_regulation of Fos 1 0.04 0.89 1.06
107 INT119887 Binding of Atf4 and Usf1 1 0.21 0.15 1.05
108 INT105109 Cxcl12 Positive_regulation of JUN 1 0.01 1.07 1.05
109 INT119888 Binding of Creb1 and Usf1 1 0.18 0.15 1.05
110 INT134970 Positive_regulation of Binding of OPRK1 and SP1 1 0.00 0 1.05
111 INT270680 Fos Regulation of Gene_expression of Tg(CAG-EGFP)D4Nagy 1 0.03 0.39 1.05
112 INT214875 Ap3d1 Negative_regulation of Gene_expression of Fos 1 0.00 0.39 1.04
113 INT134969 Binding of OPRK1 and SP1 1 0.00 0 1.04
114 INT69011 Binding of Cebpb and Nfkb1 1 0.19 0.75 1.04
115 INT146518 Tmem132a Positive_regulation of Gene_expression of Fos 1 0.68 0.06 1.04
116 INT307047 Foxm1 Positive_regulation of Casp3 1 0.11 0.06 1.03
117 INT88881 Negative_regulation of IRF6 Positive_regulation of Nfkb1 1 0.09 0.27 1.03
118 INT95378 Binding of Jun and Jund 5 0.20 2.06 1.02
119 INT74027 Creb1 Regulation of Jun 4 0.27 1.04 1.02
120 INT101065 MAP3K15 Positive_regulation of JUN 1 0.43 0.46 1.02
121 INT229914 Egr1 Positive_regulation of Phosphorylation of Mapk3 1 0.46 1.03 1.02
122 INT74934 Regulation of IRF6 Positive_regulation of Nfkb1 1 0.01 0.52 1.02
123 INT139636 Jun Negative_regulation of Phosphorylation of Npy 1 0.33 1.07 1.01
124 INT74933 IRF6 Positive_regulation of Nfkb1 1 0.02 0.52 1.01
125 INT265070 Reln Positive_regulation of Gene_expression of Fos 1 0.02 0.51 1.01
126 INT143177 Apcs Negative_regulation of Gene_expression of Fos 1 0.02 0.36 1.01
127 INT88879 Ifng Positive_regulation of Nfkb1 1 0.01 0.26 1.01
128 INT113453 Ngf Positive_regulation of JUN 1 0.27 0.6 1.01
129 INT11251 Negative_regulation of Cck Positive_regulation of Fos 2 0.48 0 1
130 INT139639 Jun Negative_regulation of Positive_regulation of Vip 1 0.53 1.07 1
131 INT139643 Jun Negative_regulation of Positive_regulation of Npy 1 0.33 1.07 1
132 INT71319 Binding of Penk and Fos 3 0.40 0.15 0.99
133 INT200323 Binding of Oprm1 and Sp3 1 0.39 0 0.99
134 INT139641 Positive_regulation of Jun Positive_regulation of Positive_regulation of Vip 1 0.37 0.95 0.99
135 INT156510 Nfkb1 Regulation of Positive_regulation of Grin1 1 0.03 0.98 0.98
136 INT94206 SP5 Regulation of Gene_expression of FOS 1 0.22 0.7 0.98
137 INT156508 Nfkb1 Regulation of Positive_regulation of Grin1 1 0.22 0.98 0.98
138 INT139642 Positive_regulation of Jun Regulation of Gene_expression of Npy 1 0.21 1.07 0.97
139 INT136420 Binding of DeltaFosB and Rorb 1 0.03 0.66 0.97
140 INT145823 Ngf Positive_regulation of Fos 1 0.52 0.95 0.97
141 INT281375 Il1r1 Negative_regulation of Gene_expression of Fos 1 0.47 0.61 0.97
142 INT145824 Negative_regulation of Ngf Positive_regulation of Fos 1 0.48 0.95 0.97
143 INT61860 Akr1d1 Regulation of Egr1 1 0.01 0 0.96
144 INT93234 Negative_regulation of Pde4b Negative_regulation of Gene_expression of Fos 1 0.41 0.1 0.96
145 INT61861 Akr1d1 Regulation of Positive_regulation of Egr1 1 0.01 0 0.96
146 INT281380 Fos Negative_regulation of Gene_expression of FSCN1 1 0.07 0.4 0.96
147 INT139638 Positive_regulation of Jun Positive_regulation of Positive_regulation of Npy 1 0.36 1.18 0.96
148 INT103833 Sp5 Positive_regulation of Fos 1 0.51 0 0.96
149 INT155044 Negative_regulation of Ceacam3 Negative_regulation of Gene_expression of Fos 1 0.61 0 0.95
150 INT155985 Nfkb1 Negative_regulation of Gene_expression of Cyp11a1 1 0.10 0.53 0.95
151 INT127263 Adra2a Regulation of Gene_expression of Jun 1 0.07 1.1 0.95
152 INT148772 Usf1 Regulation of Calca 1 0.40 0.69 0.95
153 INT130722 Binding of IL1B and Nfkb1 1 0.28 1.23 0.95
154 INT166842 Binding of ANXA1 and Nfkb1 1 0.37 1.64 0.95
155 INT155043 Vta1 Regulation of Gene_expression of Fos 1 0.08 0 0.95
156 INT152390 Negative_regulation of Binding of JUN and OPRM1 1 0.13 0.14 0.94
157 INT80601 Akr1d1 Regulation of Positive_regulation of Fos 1 0.06 0 0.94
158 INT152387 Binding of JUN and OPRM1 1 0.15 0.14 0.94
159 INT139330 Binding of SGCG and Stat1 1 0.37 0.75 0.94
160 INT149390 Foxm1 Positive_regulation of Trpa1 1 0.28 0.31 0.94
161 INT330629 TP53 Negative_regulation of Gene_expression of Fos 1 0.30 1.76 0.94
162 INT48148 Fos Positive_regulation of Gene_expression of Pdyn 1 0.21 0 0.94
163 INT186568 Hpcl1 Regulation of Gene_expression of Fos 1 0.22 0.07 0.94
164 INT73467 PTPLA Positive_regulation of Transcription of Myc 1 0.29 0.97 0.94
165 INT219154 Binding of HMGB1 and TLR4 2 0.17 4.45 0.93
166 INT281377 FSCN1 Positive_regulation of Gene_expression of Fos 1 0.08 0.49 0.93
167 INT89514 Pnoc Regulation of Gene_expression of Fos 1 0.47 0.98 0.93
168 INT120380 Cnr1 Positive_regulation of Gene_expression of Fos 1 0.31 0.45 0.93
169 INT143578 Olr404 Negative_regulation of Positive_regulation of Fos 1 0.01 0.39 0.93
170 INT86350 Negative_regulation of Adarb1 Negative_regulation of Positive_regulation of Fos 1 0.04 0.8 0.92
171 INT186431 Trib3 Regulation of Creb1 1 0.03 0.23 0.92
172 INT262165 Nr0b2 Negative_regulation of Nr5a2 1 0.02 0.5 0.92
173 INT151263 Jun Positive_regulation of S100a8 1 0.00 0.95 0.92
174 INT86349 Negative_regulation of Tacr1 Negative_regulation of Positive_regulation of Fos 1 0.42 0.8 0.92
175 INT61859 Akr1d1 Positive_regulation of Egr1 1 0.01 0 0.92
176 INT61862 Slc3a1 Positive_regulation of Egr1 1 0.05 0 0.92
177 INT252879 Creb1 Positive_regulation of Gene_expression of Tacr1 1 0.03 0.24 0.91
178 INT112765 Binding of Nfkb1 and Bcl2 1 0.00 1.37 0.91
179 INT6975 Zeb1 Positive_regulation of St8sia1 1 0.03 0.17 0.91
180 INT66536 Il1a Regulation of Gene_expression of Fos 1 0.59 0 0.91
181 INT118288 EGF Positive_regulation of Phosphorylation of EGFR 9 0.54 3.85 0.9
182 INT219037 Creb1 Positive_regulation of Transcription of Bdnf 2 0.43 1.07 0.9
183 INT166221 Negative_regulation of Gls Negative_regulation of Gene_expression of Fos 1 0.50 0.37 0.9
184 INT279166 Binding of Cyp3a23/3a1 and Nr3c2 1 0.00 0.61 0.9
185 INT256646 Tnf Positive_regulation of Positive_regulation of Nfkb1 1 0.22 1.83 0.9
186 INT77253 Binding of gr and Creb1 1 0.03 0.4 0.9
187 INT77254 Binding of gr and Sp1 1 0.04 0.4 0.9
188 INT309140 Dlat Positive_regulation of Creb1 1 0.06 1.1 0.9
189 INT128859 Positive_regulation of RXRA Regulation of Gene_expression of OPRM1 1 0.05 0.26 0.9
190 INT249347 Binding of FOS and JUN 4 0.19 6.15 0.89
191 INT152702 Nfkb1 Negative_regulation of Ltp 1 0.01 0.15 0.89
192 INT164677 Ngf Positive_regulation of Gene_expression of Fos 1 0.52 0.08 0.89
193 INT101259 Gata6 Negative_regulation of Gene_expression of ALOX15 1 0.42 0.67 0.89
194 INT142128 Nrgn Regulation of Creb1 1 0.38 0.25 0.89
195 INT152700 Negative_regulation of Nfkb1 Negative_regulation of Bdnf 1 0.04 0.15 0.89
196 INT129034 Nfkbia Positive_regulation of Nfkb1 1 0.02 0.67 0.89
197 INT152701 Nfkb1 Negative_regulation of Bdnf 1 0.04 0.15 0.89
198 INT134454 EGF Positive_regulation of EGFR 3 0.56 1.32 0.88
199 INT108687 Nfkb1 Regulation of Positive_regulation of Nos2 1 0.50 1.28 0.88
200 INT103611 Mdk Negative_regulation of Phosphorylation of Sp1 1 0.01 0.28 0.88

Single Events

The table below shows the top 100 pain related interactions that have been reported for double-stranded DNA binding. They are ordered first by their pain relevance and then by number of times they were reported in double-stranded DNA binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5200 Gene_expression of Fos 3083 0.78 894.43 1639.02
2 INT5202 Positive_regulation of Gene_expression of Fos 1163 0.70 319.28 684
3 INT5228 Positive_regulation of Fos 934 0.70 209.8 503.87
4 INT6056 Negative_regulation of Gene_expression of Fos 601 0.59 193.05 386.84
5 INT5379 Gene_expression of Fos 656 0.78 255.5 292.54
6 INT5591 Regulation of Gene_expression of Fos 425 0.62 129.06 265.78
7 INT11009 Phosphorylation of Creb1 458 0.82 111.34 221.97
8 INT6665 Gene_expression of FOS 520 0.77 165.31 217.66
9 INT11012 Positive_regulation of Creb1 258 0.70 84.4 132
10 INT5380 Positive_regulation of Gene_expression of Fos 243 0.70 105.65 131.05
11 INT65054 Positive_regulation of Nfkb1 285 0.70 149.33 126.73
12 INT11011 Positive_regulation of Phosphorylation of Creb1 190 0.70 49.25 112.01
13 INT49651 Gene_expression of Creb1 276 0.78 114.77 111.96
14 INT27096 Positive_regulation of Nfkb1 325 0.70 195.11 109.06
15 INT5587 Regulation of Fos 191 0.62 40.81 99.7
16 INT7944 Positive_regulation of Fos 193 0.70 60.69 98.31
17 INT17459 Positive_regulation of Gene_expression of FOS 182 0.67 53.45 96.38
18 INT5590 Negative_regulation of Fos 144 0.59 40.94 81.98
19 INT57380 Phosphorylation of Creb1 213 0.82 66.8 71.26
20 INT9484 Gene_expression of Jun 175 0.78 34.89 68.54
21 INT5861 Gene_expression of Egr1 203 0.78 49.35 68.13
22 INT102020 Gene_expression of Creb1 190 0.78 57.31 59.77
23 INT82055 Positive_regulation of Creb1 176 0.70 60.2 58.39
24 INT6436 Positive_regulation of Positive_regulation of Fos 101 0.70 18.71 57.96
25 INT6669 Negative_regulation of Positive_regulation of Fos 98 0.59 23.5 56.82
26 INT5356 Positive_regulation of FOS 153 0.69 54.21 56.74
27 INT17458 Negative_regulation of Gene_expression of FOS 98 0.57 36.77 55.69
28 INT8528 Negative_regulation of Gene_expression of Fos 100 0.59 41.15 55.6
29 INT69876 Negative_regulation of Nfkb1 147 0.58 89.81 55.5
30 INT6796 Positive_regulation of Jun 165 0.70 37.18 49.64
31 INT88617 Positive_regulation of Gene_expression of Creb1 90 0.69 51.69 44.29
32 INT52531 Gene_expression of Nfkb1 153 0.75 82.84 42.9
33 INT65055 Negative_regulation of Nfkb1 83 0.58 44.85 34.94
34 INT11013 Negative_regulation of Phosphorylation of Creb1 55 0.59 18.74 34.66
35 INT21527 Gene_expression of FosB 47 0.78 11.2 34.39
36 INT5862 Positive_regulation of Egr1 82 0.70 30.4 33.96
37 INT666 Gene_expression of Jun 124 0.78 54.61 33.67
38 INT16714 Regulation of Creb1 64 0.62 22.23 33.56
39 INT65536 Negative_regulation of Positive_regulation of Nfkb1 77 0.59 38.86 33.33
40 INT81530 Gene_expression of Nfkb1 93 0.78 48.58 32.58
41 INT6053 Transcription of Fos 107 0.72 20.97 31.88
42 INT47764 Binding of Jun 106 0.48 22.62 31.39
43 INT6058 Localization of Fos 73 0.81 16.7 30.84
44 INT57379 Positive_regulation of Phosphorylation of Creb1 79 0.69 28.24 30.25
45 INT6660 Positive_regulation of Jun 148 0.69 67.58 29.73
46 INT11010 Regulation of Phosphorylation of Creb1 52 0.62 7.26 29.04
47 INT53384 Positive_regulation of FosB 41 0.69 8.43 28.91
48 INT87212 Negative_regulation of Positive_regulation of Nfkb1 74 0.57 38.21 28.31
49 INT17331 Positive_regulation of JUN 132 0.69 60.4 27.03
50 INT5378 Regulation of Gene_expression of Fos 47 0.60 14.47 26.41
51 INT65537 Positive_regulation of Positive_regulation of Nfkb1 52 0.67 30.6 26.35
52 INT53385 Positive_regulation of Gene_expression of FosB 26 0.70 9.18 26.33
53 INT48979 Regulation of Gene_expression of FOS 52 0.61 14.4 25.95
54 INT6054 Positive_regulation of Gene_expression of Egr1 67 0.70 18.45 25.93
55 INT11159 Gene_expression of EGFR 698 0.78 548.93 25.69
56 INT11014 Phosphorylation of CREB1 72 0.81 26.35 25.64
57 INT57874 Gene_expression of Egr1 113 0.78 68.46 24.95
58 INT66758 Binding of Nfkb1 97 0.48 50.65 23.65
59 INT102021 Positive_regulation of Gene_expression of Creb1 66 0.70 24.04 23.28
60 INT114362 Localization of Hmgb1 127 0.78 120.28 23.26
61 INT61160 Negative_regulation of Gene_expression of Creb1 37 0.59 17.95 23.17
62 INT71875 Localization of Nfkb1 92 0.78 48.13 22.94
63 INT106175 Positive_regulation of Positive_regulation of Creb1 37 0.70 13.89 22.46
64 INT19949 Regulation of Positive_regulation of Fos 36 0.60 6.11 22.05
65 INT7573 Positive_regulation of Nr3c2 38 0.67 20 21.84
66 INT5586 Binding of Fos 47 0.48 12.7 21.33
67 INT52529 Regulation of Nfkb1 48 0.61 26.2 20.89
68 INT69877 Positive_regulation of Positive_regulation of Nfkb1 53 0.68 31.44 20.7
69 INT61159 Regulation of Gene_expression of Creb1 46 0.62 24.07 20.52
70 INT9482 Positive_regulation of Gene_expression of Jun 60 0.69 9.95 18.61
71 INT11275 Regulation of Fos 37 0.60 5.79 18.18
72 INT62577 Negative_regulation of Creb1 55 0.59 19.68 18.1
73 INT61158 Negative_regulation of Creb1 33 0.59 11.54 18.06
74 INT8526 Negative_regulation of Positive_regulation of Fos 26 0.59 5.99 17.52
75 INT102023 Regulation of Creb1 51 0.62 16.29 16.71
76 INT93361 Gene_expression of Trp53 208 0.78 175.35 16.65
77 INT80972 Gene_expression of Tp53 104 0.78 102.74 16.02
78 INT41558 Localization of Sp1 9 0.48 0.56 14.9
79 INT60197 Gene_expression of JUN 90 0.78 42.32 14.61
80 INT57878 Positive_regulation of Gene_expression of Egr1 36 0.70 20.42 14.45
81 INT17593 Regulation of Jun 37 0.60 5.5 14.35
82 INT78480 Localization of Nfkb1 39 0.80 23.14 13.64
83 INT71879 Negative_regulation of Localization of Nfkb1 30 0.57 21.8 13.48
84 INT12321 Binding of Nr3c2 19 0.46 5.44 13.46
85 INT107248 Negative_regulation of Gene_expression of Creb1 26 0.58 9.24 13.41
86 INT6794 Negative_regulation of Jun 37 0.53 8.04 13.37
87 INT86383 Negative_regulation of EGFR 258 0.59 173.94 13.32
88 INT24082 Negative_regulation of Sp1 13 0.40 1.19 13.11
89 INT16713 Binding of Creb1 53 0.48 20.24 13.06
90 INT15246 Regulation of FOS 32 0.60 15.34 12.94
91 INT114274 Gene_expression of Rxra 67 0.70 36.77 12.5
92 INT10433 Positive_regulation of Junb 35 0.70 6.55 12.42
93 INT13409 Gene_expression of NEUROD1 52 0.75 14.17 12.23
94 INT39553 Gene_expression of Hmgb1 50 0.75 51.18 12.21
95 INT9483 Gene_expression of Junb 34 0.78 3.24 12.08
96 INT15756 Positive_regulation of Gene_expression of Jun 29 0.69 16.58 12.06
97 INT12315 Gene_expression of Nr3c2 37 0.75 19.28 11.97
98 INT111476 Gene_expression of TP63 88 0.76 61.08 11.64
99 INT65057 Regulation of Nfkb1 28 0.47 16.48 11.62
100 INT19795 Positive_regulation of EGFR 161 0.70 103.69 11.55
101 INT6051 Positive_regulation of Transcription of Fos 27 0.69 6.3 11.48
102 INT70816 Negative_regulation of Fos 32 0.58 13 11.18
103 INT52233 Transcription of Jun 37 0.66 6.39 11.15
104 INT15597 Negative_regulation of Gene_expression of Jun 20 0.48 6.04 11.08
105 INT81531 Positive_regulation of Gene_expression of Nfkb1 27 0.69 13.9 11.04
106 INT79656 Positive_regulation of NR3C1 14 0.68 6.38 10.83
107 INT91774 Gene_expression of Nr3c1 27 0.78 16.14 10.7
108 INT52657 Phosphorylation of Fos 20 0.80 6.36 10.64
109 INT62576 Transcription of Creb1 34 0.69 16.97 10.6
110 INT109280 Negative_regulation of Phosphorylation of Creb1 29 0.59 11.81 10.37
111 INT60198 Binding of JUN 54 0.48 11.56 10.27
112 INT7577 Regulation of Nr3c2 16 0.56 7.7 10.1
113 INT59352 Positive_regulation of Fosb 16 0.58 1.89 10.09
114 INT17592 Positive_regulation of Regulation of Fos 21 0.67 3.54 10.07
115 INT65058 Binding of Nfkb1 36 0.45 19.87 10.02
116 INT49660 Positive_regulation of EGR1 54 0.69 32.17 9.89
117 INT169997 Positive_regulation of Gene_expression of Tp53 37 0.70 47.3 9.85
118 INT59357 Gene_expression of Fosb 36 0.78 7.81 9.68
119 INT8527 Positive_regulation of Positive_regulation of Fos 20 0.70 6.87 9.62
120 INT71878 Protein_catabolism of Nfkb1 24 0.65 10.85 9.46
121 INT57876 Positive_regulation of Egr1 46 0.70 25.6 9.41
122 INT73021 Gene_expression of EGR1 43 0.77 24.65 9.18
123 INT54588 Positive_regulation of CREB1 38 0.67 12.01 9.18
124 INT48978 Negative_regulation of FOS 41 0.57 11.94 9.14
125 INT155944 Gene_expression of Foxp3 66 0.66 24.37 9.12
126 INT109279 Regulation of Phosphorylation of Creb1 14 0.62 4.06 8.96
127 INT6019 Positive_regulation of NEUROD1 37 0.67 17.3 8.89
128 INT61264 Regulation of Jun 36 0.61 18.42 8.71
129 INT47769 Phosphorylation of Fos 20 0.61 3.03 8.68
130 INT26751 Regulation of Nr3c1 13 0.61 6.58 8.65
131 INT64815 Binding of Jun 49 0.48 21.47 8.59
132 INT169015 Gene_expression of FOXP3 50 0.60 33.18 8.4
133 INT17333 Positive_regulation of Positive_regulation of FOS 17 0.67 6.06 8.4
134 INT93673 Transcription of Creb1 19 0.66 9.27 8.26
135 INT53975 Positive_regulation of Binding of Jun 28 0.70 4.67 8.16
136 INT114363 Positive_regulation of Hmgb1 50 0.67 48.92 8.15
137 INT87271 Positive_regulation of Phosphorylation of CREB1 27 0.66 12.87 7.91
138 INT111533 Positive_regulation of Gene_expression of Nfkb1 27 0.52 17.32 7.89
139 INT121977 Phosphorylation of Nfkb1 15 0.51 9.83 7.77
140 INT116552 Positive_regulation of Localization of Nfkb1 16 0.61 12.7 7.74
141 INT6055 Transcription of Egr1 47 0.69 3.61 7.68
142 INT64816 Transcription of Jun 31 0.69 16.01 7.64
143 INT47848 Negative_regulation of Positive_regulation of FOS 14 0.57 3.78 7.63
144 INT9476 Regulation of Gene_expression of Jun 14 0.43 4.25 7.61
145 INT66318 Gene_expression of NR3C1 26 0.76 20 7.55
146 INT81537 Regulation of Gene_expression of Nfkb1 10 0.57 7.09 7.48
147 INT10344 Localization of Jun 23 0.73 6.36 7.46
148 INT212758 Binding of Hmgb1 40 0.44 35.6 7.41
149 INT9478 Positive_regulation of Gene_expression of Junb 19 0.70 2.34 7.41
150 INT49749 Negative_regulation of Nr3c1 13 0.43 6.25 7.36
151 INT96994 Phosphorylation of EGFR 99 0.82 52.75 7.33
152 INT99076 Regulation of Gene_expression of FosB 7 0.62 1.34 7.32
153 INT116619 Positive_regulation of Positive_regulation of Creb1 25 0.69 8.32 7.3
154 INT86867 Regulation of CREB1 15 0.46 4.95 7.28
155 INT97055 Positive_regulation of Gene_expression of Trp53 51 0.70 45.7 7.25
156 INT138922 Positive_regulation of Stat1 57 0.69 28.35 7.2
157 INT6057 Negative_regulation of Gene_expression of Egr1 17 0.57 4.17 7.17
158 INT64370 Gene_expression of Neurod1 22 0.75 5.19 7.1
159 INT75497 Regulation of JUN 28 0.61 11.04 7.09
160 INT106330 Regulation of Positive_regulation of Creb1 11 0.56 5.57 7.06
161 INT47707 Negative_regulation of Egr1 9 0.41 0.17 7.03
162 INT60196 Binding of FOS 33 0.47 13.11 6.95
163 INT53491 Negative_regulation of Jun 28 0.57 14.2 6.9
164 INT47817 Positive_regulation of Positive_regulation of Jun 21 0.66 3.7 6.83
165 INT114642 Negative_regulation of Positive_regulation of Creb1 12 0.57 2.32 6.75
166 INT59351 Positive_regulation of Gene_expression of Fosb 20 0.70 3.53 6.74
167 INT12314 Negative_regulation of Nr3c2 16 0.56 14.82 6.72
168 INT68653 Negative_regulation of JUN 34 0.58 14.27 6.56
169 INT48555 Binding of SP1 30 0.46 11.38 6.53
170 INT73022 Positive_regulation of Gene_expression of EGR1 21 0.69 10.61 6.5
171 INT65538 Regulation of Positive_regulation of Nfkb1 17 0.51 8.31 6.5
172 INT50337 Negative_regulation of Foxm1 24 0.43 11.12 6.48
173 INT5847 Transcription of FOS 31 0.69 11.11 6.41
174 INT47765 Negative_regulation of Binding of Jun 21 0.43 5.05 6.38
175 INT5860 Regulation of Gene_expression of Egr1 20 0.62 3.02 6.38
176 INT61258 Transcription of Nfkb1 24 0.67 10.89 6.32
177 INT11154 Binding of EGFR 149 0.48 96.23 6.29
178 INT7564 Positive_regulation of Nr3c1 16 0.68 4.98 6.25
179 INT93359 Positive_regulation of Trp53 90 0.70 69.77 6.24
180 INT6097 Negative_regulation of NEUROD1 30 0.57 9.71 6.24
181 INT92971 Binding of Creb1 31 0.47 11.3 6.22
182 INT163756 Phosphorylation of Stat1 45 0.82 14.51 6.11
183 INT38686 Binding of NR3C1 20 0.48 9.25 5.99
184 INT6098 Binding of NEUROD1 17 0.47 3.4 5.99
185 INT88873 Negative_regulation of Gene_expression of Nfkb1 24 0.56 9.93 5.97
186 INT73649 Phosphorylation of Jun 28 0.80 11.01 5.87
187 INT329292 Gene_expression of Aff3 3 0.54 3.24 5.87
188 INT41604 Negative_regulation of Localization of Sp1 2 0.30 0.32 5.86
189 INT138915 Gene_expression of Stat1 144 0.77 69.53 5.85
190 INT6667 Gene_expression of CREB1 27 0.77 6.29 5.84
191 INT52819 Negative_regulation of NR3C1 14 0.50 7.22 5.84
192 INT17892 Gene_expression of Myc 57 0.75 36.37 5.82
193 INT8525 Regulation of Positive_regulation of Fos 9 0.60 4.04 5.75
194 INT61986 Localization of Creb1 16 0.69 2.12 5.66
195 INT190520 Negative_regulation of Hmgb1 24 0.53 20.08 5.6
196 INT55513 Binding of Foxm1 19 0.37 2.37 5.54
197 INT118870 Positive_regulation of STAT1 36 0.67 26.18 5.46
198 INT112713 Gene_expression of Hif1a 24 0.75 20.48 5.45
199 INT52814 Negative_regulation of Nr3c1 9 0.57 5.69 5.41
200 INT92398 Negative_regulation of Localization of Nfkb1 17 0.42 11.24 5.4
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