GO:0003697

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Name single-stranded DNA binding
Categary Function
Go Slim No
Go Link GO:0003697
Unique Molecular Interactions 194
Total Molecular Interactions 287
Total Single Events 1907
Pain Genes Associated 44

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for single-stranded DNA binding. They are ordered first by their pain relevance and then by number of times they were reported for single-stranded DNA binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT287746 Anxa1 Positive_regulation of Gene_expression of Lpar1 1 0.07 1.72 2.46
2 INT184262 Binding of AGER and HMGB1 1 0.34 4.49 2.17
3 INT215100 Binding of Hmgb1 and Tlr4 5 0.29 3.21 1.68
4 INT215096 Binding of Hmgb1 and Tlr2 9 0.38 11.61 1.61
5 INT114364 Hmgb1 Positive_regulation of Gene_expression of TNF 2 0.05 1.85 1.06
6 INT166842 Binding of ANXA1 and Nfkb1 1 0.37 1.64 0.95
7 INT219154 Binding of HMGB1 and TLR4 2 0.17 4.45 0.93
8 INT266408 Binding of HMGB1 and Ager 1 0.01 2.57 0.76
9 INT253759 Hmgb1 Positive_regulation of Apex1 1 0.09 4.53 0.69
10 INT215093 Tlr4 Positive_regulation of Localization of Hmgb1 1 0.32 2.9 0.68
11 INT206206 Binding of Mcf2l and Obfc1 1 0.02 1.11 0.64
12 INT253760 Hmgb1 Positive_regulation of Gene_expression of Apex1 1 0.10 3.53 0.58
13 INT181471 Binding of Il10 and Ptbp1 1 0.05 2.14 0.58
14 INT27871 Binding of FCGR1B and HSPD1 1 0.01 1.93 0.56
15 INT27872 Positive_regulation of Binding of FCGR1B and HSPD1 1 0.01 1.93 0.56
16 INT166840 Binding of Anxa1 and Nfkb1 1 0.26 0.82 0.56
17 INT323611 Il1 Regulation of Hmgb1 1 0.17 2.36 0.55
18 INT215101 Hmgb1 Positive_regulation of Localization of Il6 4 0.16 1.18 0.54
19 INT253767 Binding of Hmgb1 and Tlr9 2 0.12 1.78 0.52
20 INT103535 Obfc1 Negative_regulation of Positive_regulation of Gad1 1 0.03 0.07 0.49
21 INT253770 Hmgb1 Positive_regulation of Localization of Apex1 1 0.08 0.71 0.49
22 INT346325 Sirpa Regulation of Obfc1 1 0.00 0.41 0.48
23 INT58578 Binding of RPA1 and TACR1 1 0.01 0 0.48
24 INT95276 Obfc2a Negative_regulation of Nos3 1 0.02 1.02 0.46
25 INT103536 Obfc1 Regulation of Gene_expression of Penk 1 0.00 0.08 0.46
26 INT296237 Anxa1 Regulation of Gene_expression of Trpm8 1 0.03 0.57 0.43
27 INT296231 Anxa1 Regulation of Gene_expression of Trpa1 1 0.03 0.57 0.43
28 INT344104 Binding of Slc6a3 and Obfc1 1 0.00 0 0.43
29 INT296235 Trpm8 Regulation of Positive_regulation of Anxa1 1 0.03 0.62 0.41
30 INT121972 Sub1 Positive_regulation of Fos 1 0.38 0 0.39
31 INT344103 Positive_regulation of Drd1a Positive_regulation of Obfc1 1 0.00 0 0.38
32 INT266419 HMGB1 Positive_regulation of Ager 1 0.01 1.37 0.37
33 INT324823 Tlr4 Positive_regulation of Gene_expression of Hmgb1 1 0.21 0.51 0.37
34 INT324803 Hmgb1 Positive_regulation of Gene_expression of Bad 1 0.02 0.44 0.37
35 INT324818 Hmgb1 Positive_regulation of Gene_expression of Tlr4 1 0.21 0.51 0.37
36 INT324819 Hmgb1 Positive_regulation of Gene_expression of Maob 1 0.09 0.44 0.37
37 INT324827 Hmgb1 Positive_regulation of Bad 1 0.02 0.43 0.36
38 INT344238 MCRS1 Regulation of TREX1 1 0.08 1.02 0.34
39 INT253762 Binding of Apex1 and Hmgb1 1 0.09 1.29 0.32
40 INT160439 Sub1 Regulation of Trpc6 1 0.21 0.17 0.32
41 INT287747 Anxa1 Positive_regulation of Lpar1 1 0.04 0 0.29
42 INT287748 Positive_regulation of Anxa1 Positive_regulation of Lpar1 1 0.04 0 0.29
43 INT323612 Negative_regulation of Tlr4 Positive_regulation of Hmgb1 1 0.23 0.2 0.25
44 INT323610 Tlr4 Positive_regulation of Hmgb1 1 0.25 0.2 0.25
45 INT111909 Binding of HSPD1 and CCT4 1 0.29 0.48 0.25
46 INT111908 Binding of HSPD1 and AP4B1 1 0.03 0.48 0.25
47 INT253765 Apex1 Positive_regulation of Hmgb1 1 0.09 1.27 0.24
48 INT343914 Hmgb1 Positive_regulation of Gene_expression of IL12A 1 0.01 0.41 0.24
49 INT253771 Gopc Positive_regulation of Hmgb1 1 0.03 1.27 0.24
50 INT343906 Hmgb1 Positive_regulation of Gene_expression of Cd40 1 0.05 0.41 0.24
51 INT266421 Binding of HMGB1 and Il1 1 0.02 0.37 0.24
52 INT253773 TNF Positive_regulation of Hmgb1 1 0.09 1.21 0.23
53 INT266418 Binding of HMGB1 and Tlr4 1 0.09 0.37 0.23
54 INT332481 ANXA1 Regulation of SGPP2 1 0.45 1.01 0.22
55 INT344833 Binding of Ager and Hmgb1 1 0.08 0.72 0.22
56 INT182606 Binding of MSH2 and MSH3 1 0.12 1.4 0.21
57 INT322017 RPA1 Positive_regulation of IL1B 1 0.00 0 0.21
58 INT121973 Sub1 Regulation of Gene_expression of Fos 1 0.32 0 0.21
59 INT266423 Binding of HMGB1 and Mapk3 1 0.04 0.9 0.2
60 INT333053 IL6 Positive_regulation of Gene_expression of HNRNPA1 1 0.02 2.39 0.2
61 INT266410 Binding of HMGB1 and Mapk14 1 0.03 0.91 0.2
62 INT266416 Binding of HMGB1 and Mapk1 1 0.06 0.9 0.2
63 INT266414 Binding of HMGB1 and Mapk8 1 0.03 0.91 0.2
64 INT266404 Binding of HMGB1 and Thbd 1 0.06 0.3 0.2
65 INT258289 Hmgb1 Positive_regulation of Tlr2 4 0.48 3.61 0.19
66 INT324815 Binding of Hmgb1 and Caprin1 1 0.01 0.65 0.19
67 INT91862 RPA1 Negative_regulation of Transcription of ATG9B 1 0.03 0.46 0.19
68 INT324797 Binding of Cd24a and Hmgb1 1 0.19 0.66 0.19
69 INT323613 Il1 Regulation of Localization of Hmgb1 1 0.10 0.75 0.19
70 INT231763 Binding of HSPD1 and TLR2 1 0.12 2 0.19
71 INT251492 Binding of HSPD1 and SOD1 1 0.02 1.45 0.18
72 INT58579 Binding of INSRR and RPA1 1 0.00 0 0.18
73 INT215094 Il6 Positive_regulation of Hmgb1 1 0.18 1.84 0.17
74 INT344832 Hmgb1 Positive_regulation of Gene_expression of Nos2 1 0.12 0.82 0.17
75 INT266422 HMGB1 Positive_regulation of Binding of Ager 1 0.01 0.92 0.16
76 INT231765 Binding of HSPD1 and TLR4 1 0.13 1.94 0.16
77 INT29207 Msh2 Regulation of POMC 1 0.02 0.1 0.14
78 INT266413 Positive_regulation of Binding of HMGB1 and Col4a1 1 0.02 1.05 0.14
79 INT266411 Binding of HMGB1 and Col4a1 1 0.01 1.05 0.14
80 INT296233 Binding of Anxa1 and Trpa1 1 0.03 0.78 0.14
81 INT343920 Binding of TLR4 and Hmgb1 1 0.39 0.97 0.13
82 INT324866 Hmgb1 Positive_regulation of Tlr4 1 0.16 1.29 0.13
83 INT332485 SGPP2 Regulation of ANXA1 1 0.27 0.69 0.13
84 INT343917 Binding of IRF6 and Hmgb1 1 0.05 0.98 0.13
85 INT220527 Nme1 Negative_regulation of Positive_regulation of Vegfa 1 0.00 1.23 0.12
86 INT253761 Hmgb1 Positive_regulation of Gene_expression of Gopc 1 0.03 0.73 0.12
87 INT163418 Sub1 Positive_regulation of Pscs 1 0.07 0.23 0.12
88 INT253772 Binding of THBD and Hmgb1 1 0.05 0.95 0.12
89 INT253775 Negative_regulation of Binding of THBD and Hmgb1 1 0.06 0.69 0.12
90 INT182607 Binding of MLH1 and MSH3 1 0.04 0.81 0.11
91 INT276064 Src Regulation of Positive_regulation of Rpa1 1 0.02 0.18 0.11
92 INT192358 CRP Regulation of Positive_regulation of HSPD1 1 0.15 2.46 0.1
93 INT69909 Binding of MYC and PURA 1 0.24 0 0.1
94 INT276041 Positive_regulation of Gabbr2 Negative_regulation of Positive_regulation of Rpa1 1 0.01 0 0.1
95 INT303815 Binding of Igfals and Tdp1 1 0.11 1.68 0.1
96 INT311738 Binding of Anxa1 and Plat 1 0.19 0.63 0.1
97 INT192352 CRP Regulation of HSPD1 1 0.15 2.46 0.1
98 INT276039 Positive_regulation of Car2 Positive_regulation of Positive_regulation of Rpa1 1 0.04 0 0.09
99 INT216943 Rtf1 Regulation of Localization of Il10 1 0.02 0.35 0.09
100 INT215095 Negative_regulation of Il6 Positive_regulation of Hmgb1 1 0.13 1.03 0.09
101 INT74742 OBFC1 Negative_regulation of Positive_regulation of Pdyn 1 0.00 0.45 0.09
102 INT74740 OBFC1 Negative_regulation of Positive_regulation of Penk 1 0.00 0.45 0.09
103 INT250730 Hmgb1 Positive_regulation of Localization of TNF 1 0.08 0.92 0.09
104 INT74741 Negative_regulation of OBFC1 Negative_regulation of Positive_regulation of Pdyn 1 0.00 0.45 0.09
105 INT282684 FECH Positive_regulation of Negative_regulation of Ssbp3 1 0.00 1.54 0.08
106 INT346323 Binding of Gopc and Obfc1 1 0.01 0 0.08
107 INT220237 IL1B Regulation of Gene_expression of LONP1 1 0.03 0 0.08
108 INT220248 IL1RN Regulation of Gene_expression of LONP1 1 0.04 0 0.08
109 INT276049 Pde1b Regulation of Positive_regulation of Rpa1 1 0.04 0 0.06
110 INT258290 Hmgb1 Regulation of Positive_regulation of Tlr2 1 0.46 1.04 0.05
111 INT333849 Binding of Mcm4 and Mir17 1 0.03 0.52 0.05
112 INT296236 Anxa1 Positive_regulation of Trpm8 1 0.04 0.09 0.05
113 INT332484 ANXA1 Positive_regulation of HSH2D 1 0.18 0.19 0.05
114 INT333841 Binding of Rad51 and Mir17 1 0.02 0.52 0.05
115 INT206845 ANXA1 Regulation of Gene_expression of ESR1 1 0.07 0.9 0.04
116 INT296232 Anxa1 Regulation of Trpm8 1 0.03 0.54 0.04
117 INT291174 Rpa1 Positive_regulation of Baat 1 0.03 0.63 0.04
118 INT276076 Camk2a Positive_regulation of Rpa1 1 0.07 0 0.03
119 INT276072 Car2 Regulation of Gene_expression of Rpa1 1 0.03 0 0.03
120 INT222532 Anxa1 Negative_regulation of Localization of Gh1 1 0.01 0.14 0.03
121 INT324859 Hmgb1 Positive_regulation of ecs 1 0.03 0.74 0.03
122 INT324798 Hmgb1 Positive_regulation of Positive_regulation of Mthfd1 1 0.04 0.16 0.03
123 INT346324 Binding of Erh and Obfc1 1 0.03 0 0.03
124 INT222538 Anxa1 Negative_regulation of Localization of Prl 1 0.04 0.14 0.03
125 INT222475 Anxa1 Negative_regulation of Localization of LH 1 0.01 0.14 0.03
126 INT290556 Binding of MLH1 and MSH2 3 0.34 2.74 0
127 INT234178 Binding of BRCA1 and BRCA2 2 0.40 1.52 0
128 INT190061 Binding of MLH1 and Mlh1 1 0.01 0.92 0
129 INT189375 Rpa1 Regulation of ERCC6 1 0.04 0.05 0
130 INT313597 Binding of BRCA2 and TOX3 1 0.11 0.7 0
131 INT324561 Hmgb1 Positive_regulation of Gene_expression of Arc 1 0.18 0.65 0
132 INT192354 Binding of CRP and HSPD1 1 0.12 1.28 0
133 INT57107 Binding of Msh2 and Nts 1 0.22 0.22 0
134 INT314742 Binding of RAD51 and Brca2 1 0.06 1.05 0
135 INT300616 Binding of MLH1 and PMS2 1 0.36 0.53 0
136 INT276075 Negative_regulation of Rtcd1 Negative_regulation of Positive_regulation of Rpa1 1 0.00 0 0
137 INT301246 Binding of HMGB1 and Hbp1 1 0.03 0.74 0
138 INT234182 Binding of BRCA2 and PALB2 1 0.41 1.43 0
139 INT189373 Rpa1 Negative_regulation of ERCC6 1 0.03 0 0
140 INT121318 Tgfb1 Negative_regulation of Ercc1 1 0.06 0.08 0
141 INT336537 Binding of Clock and Cry2 1 0.32 0 0
142 INT314743 Binding of RAD51 and Brca1 1 0.06 1.06 0
143 INT275037 gp Regulation of Obfc1 1 0.00 0 0
144 INT342252 Binding of Ercc1 and Tymp 1 0.29 1.24 0
145 INT303822 Tdp1 Regulation of TREH 1 0.02 0.92 0
146 INT276066 Gabbr2 Negative_regulation of Positive_regulation of Rpa1 1 0.01 0 0
147 INT276045 Myoz1 Regulation of Positive_regulation of Rpa1 1 0.00 0 0
148 INT311384 Binding of Cnbp and Eef2 1 0.07 0.15 0
149 INT253769 Binding of Hmgb1 and Il1 1 0.01 0.27 0
150 INT285772 ERCC1 Positive_regulation of Binding of RAD51 1 0.05 0 0
151 INT229935 YBX1 Negative_regulation of C4B 1 0.00 0 0
152 INT121313 Tgfb1 Positive_regulation of Ercc1 1 0.07 0.08 0
153 INT206844 ESR1 Positive_regulation of Gene_expression of ANXA1 1 0.08 0.1 0
154 INT121315 Negative_regulation of Egfr Negative_regulation of Ercc1 1 0.42 0.08 0
155 INT311392 Binding of Cnbp and Pabpc1 1 0.04 0.14 0
156 INT241077 Binding of Oprm1 and Pcbp1 1 0.35 0 0
157 INT253630 Binding of HNRNPA1 and Npm1 1 0.00 0.19 0
158 INT311378 Binding of Cnbp and Rps17 1 0.06 0.14 0
159 INT285771 ERCC1 Regulation of Binding of RAD51 1 0.05 0 0
160 INT332487 ANXA1 Regulation of Gene_expression of SGPP2 1 0.45 0.08 0
161 INT260074 Binding of BRCA2 and PTCH1 1 0.40 0.15 0
162 INT268317 Cdk1 Positive_regulation of Mcm7 1 0.33 0.25 0
163 INT268324 Cdc20 Positive_regulation of Mcm7 1 0.09 0.25 0
164 INT189374 Binding of RAD51 and Rad54l 1 0.01 0 0
165 INT276054 Positive_regulation of Car2 Positive_regulation of Rpa1 1 0.04 0 0
166 INT190062 Binding of MLH1 and Msh2 1 0.01 0.91 0
167 INT324558 Hmgb1 Positive_regulation of Gene_expression of Kiss1 1 0.24 0.65 0
168 INT300617 Binding of MSH6 and MLH1 1 0.28 0.53 0
169 INT269139 Binding of Csnk2a2 and Sub1 1 0.02 0.68 0
170 INT251822 Binding of POLG and C10orf2 1 0.42 0.29 0
171 INT245039 Binding of Xrcc1 and Tdp1 1 0.39 0.77 0
172 INT286186 Binding of Blm and Fig4 1 0.09 0.34 0
173 INT260072 Binding of BRCA2 and FANCC 1 0.37 0.63 0
174 INT336534 Binding of Arntl and Cry2 1 0.37 0 0
175 INT211778 Binding of PCBP1 and PLVAP 1 0.07 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for single-stranded DNA binding. They are ordered first by their pain relevance and then by number of times they were reported in single-stranded DNA binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT114362 Localization of Hmgb1 127 0.78 120.28 23.26
2 INT39553 Gene_expression of Hmgb1 50 0.75 51.18 12.21
3 INT111335 Gene_expression of HSPD1 57 0.75 55.51 10.38
4 INT62544 Gene_expression of Anxa1 21 0.47 13.56 9.71
5 INT114363 Positive_regulation of Hmgb1 50 0.67 48.92 8.15
6 INT212758 Binding of Hmgb1 40 0.44 35.6 7.41
7 INT104673 Positive_regulation of Obfc1 10 0.41 4.26 5.61
8 INT190520 Negative_regulation of Hmgb1 24 0.53 20.08 5.6
9 INT184269 Gene_expression of HMGB1 51 0.77 42.96 4.55
10 INT215071 Positive_regulation of Localization of Hmgb1 34 0.63 22.03 4.15
11 INT215085 Positive_regulation of Gene_expression of Hmgb1 17 0.63 16.81 4.13
12 INT215074 Negative_regulation of Localization of Hmgb1 28 0.57 15.09 4
13 INT184288 Localization of HMGB1 20 0.61 14.5 3.84
14 INT85497 Gene_expression of Anxa1 6 0.77 4.7 3.68
15 INT62547 Positive_regulation of Gene_expression of Anxa1 5 0.42 4.52 3.27
16 INT48042 Positive_regulation of Anxa1 5 0.50 3.64 3.19
17 INT138319 Positive_regulation of Rpa1 3 0.07 2.75 3.07
18 INT134798 Gene_expression of ANXA1 15 0.75 13.94 2.99
19 INT103533 Negative_regulation of Obfc1 6 0.54 1.79 2.98
20 INT103529 Regulation of Obfc1 11 0.22 1.61 2.84
21 INT15204 Negative_regulation of Sub1 5 0.32 0.43 2.75
22 INT165726 Positive_regulation of Anxa1 7 0.29 3.16 2.57
23 INT303796 Gene_expression of Tdp1 1 0.77 70.15 2.55
24 INT184272 Binding of HMGB1 14 0.37 8.78 2.49
25 INT139295 Gene_expression of Obfc1 11 0.42 2.93 2.43
26 INT52357 Gene_expression of Sub1 6 0.16 2.49 2.25
27 INT27880 Positive_regulation of HSPD1 17 0.65 18.16 2.23
28 INT152436 Positive_regulation of Gene_expression of HSPD1 12 0.67 10.06 2.16
29 INT166838 Positive_regulation of ANXA1 4 0.64 4.88 2.16
30 INT55106 Positive_regulation of Sub1 8 0.20 3.81 1.93
31 INT51368 Regulation of Sub1 1 0.09 1.95 1.86
32 INT253755 Regulation of Hmgb1 7 0.55 6.23 1.8
33 INT27881 Binding of HSPD1 10 0.31 9.2 1.78
34 INT86909 Negative_regulation of MSH2 9 0.41 12.65 1.7
35 INT85498 Positive_regulation of Gene_expression of Anxa1 3 0.50 2.12 1.7
36 INT107992 Gene_expression of MSH2 39 0.78 37.09 1.6
37 INT198663 Positive_regulation of HMGB1 14 0.52 11.41 1.58
38 INT184271 Positive_regulation of Gene_expression of HMGB1 7 0.41 6.17 1.53
39 INT85499 Regulation of Anxa1 1 0.27 1.88 1.52
40 INT333071 Gene_expression of HNRNPA1 1 0.04 22.7 1.47
41 INT107985 Gene_expression of MLH1 29 0.67 31.31 1.46
42 INT58581 Binding of RPA1 8 0.44 1.68 1.44
43 INT139296 Positive_regulation of Gene_expression of Obfc1 4 0.31 2.18 1.38
44 INT121307 Gene_expression of Ercc1 4 0.73 12.69 1.37
45 INT300926 Gene_expression of OBFC1 15 0.65 6.97 1.22
46 INT112891 Regulation of Gene_expression of HSPD1 2 0.43 3.98 1.17
47 INT219168 Positive_regulation of Localization of HMGB1 5 0.36 4 1.16
48 INT91872 Gene_expression of RPA1 9 0.77 5.28 1.12
49 INT86908 Negative_regulation of MLH1 7 0.43 6.98 1.12
50 INT167477 Regulation of TREX1 1 0.24 1.04 1.12
51 INT215077 Negative_regulation of Positive_regulation of Hmgb1 3 0.42 5.09 1.05
52 INT71233 Negative_regulation of Anxa1 1 0.07 0.15 1.05
53 INT228871 Negative_regulation of Gene_expression of Anxa1 2 0.03 1.92 1.01
54 INT92139 Binding of MLH1 12 0.42 15.62 1
55 INT122151 Localization of Anxa1 1 0.75 0.53 1
56 INT215363 Regulation of HSPD1 4 0.51 2.74 0.99
57 INT215078 Negative_regulation of Gene_expression of Hmgb1 4 0.41 4.3 0.96
58 INT167702 Negative_regulation of Rpa1 3 0.06 1.16 0.96
59 INT354452 Gene_expression of Pcbp1 1 0.07 1.34 0.82
60 INT333086 Positive_regulation of Gene_expression of HNRNPA1 1 0.03 12.29 0.82
61 INT295239 Negative_regulation of Anxa1 2 0.02 1.6 0.81
62 INT332756 Localization of TREX1 1 0.01 0 0.81
63 INT147433 Gene_expression of BRCA2 7 0.62 7.02 0.79
64 INT190522 Regulation of Gene_expression of Hmgb1 1 0.39 1.47 0.77
65 INT164813 Localization of Obfc1 3 0.15 0.36 0.76
66 INT51369 Negative_regulation of Negative_regulation of Sub1 1 0.08 0.14 0.76
67 INT92142 Binding of MSH2 5 0.46 5.64 0.75
68 INT69914 Binding of PURA 1 0.29 0.1 0.73
69 INT303799 Phosphorylation of Tdp1 1 0.82 22.84 0.71
70 INT276010 Regulation of Positive_regulation of Rpa1 1 0.06 0.72 0.7
71 INT25176 Regulation of Msh2 3 0.37 0.48 0.68
72 INT128314 Gene_expression of Cry2 2 0.46 0.18 0.68
73 INT128326 Regulation of Gene_expression of Cry2 1 0.03 0.09 0.68
74 INT346318 Positive_regulation of Obfc1 1 0.05 0.98 0.66
75 INT167701 Phosphorylation of Rpa1 1 0.01 0.16 0.61
76 INT241060 Binding of Obfc1 2 0.04 0.19 0.59
77 INT303804 Localization of Tdp1 1 0.80 11.71 0.59
78 INT184277 Regulation of Localization of HMGB1 1 0.37 1.15 0.58
79 INT166836 Negative_regulation of Positive_regulation of ANXA1 2 0.39 1.15 0.57
80 INT122149 Binding of Anxa1 1 0.36 0.22 0.57
81 INT37750 Localization of ANXA1 2 0.74 1.72 0.56
82 INT37749 Positive_regulation of Localization of ANXA1 1 0.01 0.67 0.53
83 INT25175 Gene_expression of Msh2 2 0.55 0.4 0.52
84 INT146545 Negative_regulation of Gene_expression of MSH2 17 0.56 18.87 0.51
85 INT206876 Positive_regulation of Gene_expression of ANXA1 3 0.39 1.68 0.51
86 INT166837 Binding of ANXA1 2 0.34 0.85 0.51
87 INT343799 Negative_regulation of Transcription of HMGB1 1 0.32 0.37 0.5
88 INT215070 Regulation of Localization of Hmgb1 4 0.26 2.23 0.49
89 INT220339 Transcription of HMGB1 2 0.53 2.03 0.49
90 INT221391 Localization of Sub1 1 0.06 0.18 0.49
91 INT138404 Regulation of Negative_regulation of TREX1 1 0.18 0.18 0.46
92 INT138405 Negative_regulation of TREX1 1 0.37 0.18 0.46
93 INT206858 Regulation of ANXA1 3 0.56 2.4 0.45
94 INT206204 Gene_expression of Obfc1 2 0.07 0.58 0.45
95 INT219178 Negative_regulation of Localization of HMGB1 1 0.22 1.26 0.45
96 INT122150 Positive_regulation of Localization of Anxa1 1 0.47 0.28 0.44
97 INT166839 Negative_regulation of ANXA1 1 0.37 0.88 0.43
98 INT156931 Gene_expression of Sub1 6 0.26 0.16 0.42
99 INT121310 Positive_regulation of Ercc1 2 0.45 1.78 0.42
100 INT352592 Positive_regulation of Negative_regulation of Hmgb1 1 0.44 1.31 0.42
101 INT251828 Negative_regulation of C10orf2 3 0.37 2.87 0.41
102 INT275035 Transcription of Obfc1 2 0.06 0.86 0.41
103 INT346321 Regulation of Obfc1 1 0.03 0 0.4
104 INT219001 Gene_expression of ERCC1 12 0.54 3.77 0.38
105 INT121969 Transcription of Sub1 2 0.44 0 0.38
106 INT58580 Positive_regulation of Binding of RPA1 2 0.43 0 0.38
107 INT121968 Negative_regulation of Transcription of Sub1 1 0.27 0 0.38
108 INT306291 Localization of HSPD1 1 0.31 0.81 0.36
109 INT275992 Positive_regulation of Positive_regulation of Rpa1 1 0.05 0.31 0.36
110 INT303808 Positive_regulation of Gene_expression of Tdp1 1 0.69 9.07 0.35
111 INT69910 Positive_regulation of PURA 1 0.25 0.1 0.34
112 INT69921 Positive_regulation of Binding of PURA 1 0.26 0.1 0.34
113 INT303811 Binding of Tdp1 1 0.37 8.69 0.33
114 INT117968 Regulation of Anxa1 1 0.39 1.36 0.31
115 INT344110 Localization of Obfc1 1 0.02 0 0.31
116 INT258283 Positive_regulation of Positive_regulation of Hmgb1 3 0.44 3.1 0.3
117 INT331591 Transcription of Hmgb1 1 0.28 0.92 0.3
118 INT181468 Positive_regulation of Ptbp1 1 0.06 1.05 0.3
119 INT189335 Gene_expression of Rpa1 2 0.07 0.07 0.27
120 INT209260 Positive_regulation of Gene_expression of Sub1 1 0.02 0 0.27
121 INT69919 Regulation of PURA 1 0.37 0.1 0.26
122 INT333075 Positive_regulation of HNRNPA1 1 0.03 1.07 0.26
123 INT317008 Negative_regulation of Gene_expression of OBFC1 1 0.07 0.27 0.26
124 INT173223 Negative_regulation of BRCA2 7 0.54 6.79 0.25
125 INT166356 Negative_regulation of HSPD1 4 0.55 3 0.23
126 INT121311 Positive_regulation of Gene_expression of Ercc1 3 0.62 1.23 0.21
127 INT220336 Negative_regulation of HMGB1 3 0.43 0.97 0.21
128 INT344883 Binding of TREX1 1 0.25 0.09 0.21
129 INT266367 Positive_regulation of Binding of HMGB1 1 0.26 0.31 0.21
130 INT275996 Negative_regulation of Positive_regulation of Rpa1 1 0.05 0.44 0.2
131 INT220488 Gene_expression of Nme1 1 0.01 2.44 0.2
132 INT19359 Binding of BRCA2 5 0.47 2.63 0.19
133 INT266364 Protein_catabolism of HMGB1 1 0.34 0.29 0.19
134 INT333072 Regulation of Gene_expression of HNRNPA1 1 0.03 2.52 0.19
135 INT235538 Positive_regulation of Binding of HSPD1 1 0.08 1.15 0.19
136 INT303812 Regulation of Tdp1 1 0.45 3.32 0.19
137 INT181920 Gene_expression of MSH3 2 0.50 2.54 0.18
138 INT89690 Binding of Brca2 2 0.37 1.8 0.18
139 INT182627 Regulation of MSH2 1 0.26 2.27 0.18
140 INT169875 Negative_regulation of Ercc1 3 0.43 3.07 0.17
141 INT216933 Gene_expression of Rtf1 1 0.13 0.67 0.17
142 INT226416 Negative_regulation of Mcm4 1 0.13 1.29 0.17
143 INT266353 Negative_regulation of Binding of HMGB1 1 0.22 0.22 0.17
144 INT91870 Negative_regulation of Gene_expression of RPA1 1 0.58 0.4 0.16
145 INT258272 Negative_regulation of Binding of Hmgb1 1 0.53 1.82 0.15
146 INT91871 Transcription of RPA1 1 0.69 0.38 0.15
147 INT333079 Negative_regulation of HNRNPA1 1 0.03 2.22 0.15
148 INT91866 Positive_regulation of Gene_expression of RPA1 1 0.69 0.38 0.15
149 INT112774 Binding of Obfc1 2 0.03 0.58 0.14
150 INT199870 Gene_expression of YBX1 1 0.04 0.1 0.14
151 INT236392 Regulation of Rad51 1 0.00 0.3 0.14
152 INT287734 Binding of Anxa1 1 0.03 0.18 0.14
153 INT344828 Protein_catabolism of Hmgb1 1 0.48 0.67 0.14
154 INT344810 Positive_regulation of Protein_catabolism of Hmgb1 1 0.27 0.67 0.14
155 INT89691 Regulation of Brca2 1 0.23 0.56 0.13
156 INT182621 Localization of MLH1 9 0.64 9.31 0.12
157 INT181744 Negative_regulation of Gene_expression of MLH1 3 0.05 7.67 0.12
158 INT147244 Regulation of MLH1 3 0.08 2.64 0.12
159 INT182623 Localization of MSH2 3 0.77 5.49 0.12
160 INT163416 Positive_regulation of Sub1 2 0.25 0.52 0.12
161 INT182626 Localization of MSH3 1 0.22 0.77 0.12
162 INT220490 Positive_regulation of Nme1 1 0.01 2.57 0.12
163 INT182622 Regulation of MSH3 1 0.08 0.77 0.12
164 INT276003 Regulation of Gene_expression of Rpa1 1 0.05 0.07 0.12
165 INT276014 Regulation of Rpa1 4 0.04 0.08 0.11
166 INT181745 Positive_regulation of MSH2 4 0.48 5.73 0.11
167 INT253626 Binding of HNRNPA1 3 0.02 1.87 0.11
168 INT192360 Positive_regulation of Positive_regulation of HSPD1 1 0.29 0.77 0.11
169 INT296223 Regulation of Localization of Anxa1 1 0.03 0.35 0.11
170 INT302693 Localization of C10orf2 1 0.59 1 0.11
171 INT302695 Negative_regulation of Localization of C10orf2 1 0.33 1 0.11
172 INT296227 Localization of Anxa1 1 0.05 0.34 0.11
173 INT318343 Regulation of Binding of Hmgb1 1 0.11 0.41 0.1
174 INT226076 Regulation of RPA1 1 0.25 0.43 0.1
175 INT206737 Negative_regulation of Gene_expression of HMGB1 3 0.32 3.48 0.09
176 INT194320 Localization of RPA1 2 0.06 0.17 0.09
177 INT286183 Regulation of Blm 1 0.36 1.3 0.09
178 INT215368 Regulation of Positive_regulation of HSPD1 1 0.38 0.51 0.09
179 INT15504 Positive_regulation of Msh2 1 0.33 0.15 0.09
180 INT334739 Binding of Rpa1 1 0.03 0 0.09
181 INT74739 Negative_regulation of OBFC1 1 0.00 0.44 0.09
182 INT303805 Positive_regulation of Phosphorylation of Tdp1 1 0.50 3.27 0.09
183 INT286184 Gene_expression of Blm 1 0.39 2.16 0.09
184 INT285813 Negative_regulation of ERCC1 13 0.30 2.03 0.08
185 INT332857 Binding of Cry2 2 0.32 0 0.08
186 INT290117 Negative_regulation of Gene_expression of ANXA1 1 0.57 1.15 0.08
187 INT282678 Negative_regulation of Ssbp3 1 0.02 1.53 0.08
188 INT303795 Negative_regulation of Tdp1 1 0.43 1.71 0.08
189 INT156174 Positive_regulation of Gene_expression of Sub1 1 0.01 0.47 0.08
190 INT251831 Positive_regulation of C10orf2 1 0.50 1.23 0.08
191 INT303806 Negative_regulation of Gene_expression of Tdp1 1 0.58 3.26 0.08
192 INT220262 Gene_expression of LONP1 1 0.05 0 0.08
193 INT332843 Negative_regulation of Binding of Cry2 1 0.33 0 0.08
194 INT234186 Localization of BRCA2 2 0.69 1.48 0.07
195 INT275031 Positive_regulation of Negative_regulation of Obfc1 1 0.04 0.55 0.07
196 INT248969 Transcription of Cry2 2 0.59 0.56 0.06
197 INT253625 Localization of HNRNPA1 2 0.04 1.13 0.06
198 INT275034 Negative_regulation of Gene_expression of Obfc1 1 0.03 0 0.06
199 INT319275 Regulation of Sub1 1 0.07 0.57 0.06
200 INT303801 Positive_regulation of Tdp1 1 0.60 9.8 0.06
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