GO:0003705

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Name sequence-specific distal enhancer binding RNA polymerase II transcription factor activity
Categary Function
Go Slim No
Go Link GO:0003705
Unique Molecular Interactions 1717
Total Molecular Interactions 2432
Total Single Events 17869
Pain Genes Associated 113

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for sequence-specific distal enhancer binding RNA polymerase II transcription factor activity. They are ordered first by their pain relevance and then by number of times they were reported for sequence-specific distal enhancer binding RNA polymerase II transcription factor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT170447 Binding of Pax3 and Spr 1 0.01 0.1 5.37
2 INT126335 Binding of Pax3 and Tac1 6 0.07 6.22 5.27
3 INT113080 Drd1a Positive_regulation of Phosphorylation of Creb1 2 0.27 0.43 3.88
4 INT17317 Binding of Jun and Fos 7 0.42 1.03 3.5
5 INT161164 Prkcg Regulation of Phosphorylation of Creb1 3 0.41 0.62 3.11
6 INT309150 Edc4 Positive_regulation of Creb1 1 0.03 3.46 3.09
7 INT113234 Binding of Pax3 and Tacr1 3 0.12 1.54 2.93
8 INT190167 Binding of JUN and MMP12 1 0.26 0.82 2.76
9 INT294909 Pax3 Positive_regulation of Gene_expression of Il6 1 0.09 5.43 2.51
10 INT54489 Binding of Jun and Rabep2 4 0.16 1.48 2.3
11 INT156622 Umod Regulation of Phosphorylation of Creb1 1 0.05 0.33 2.27
12 INT158964 FosB Negative_regulation of Creb1 1 0.21 0 2.07
13 INT114927 Positive_regulation of Binding of Oprm1 and Creb1 1 0.17 0.28 2.07
14 INT114923 Binding of Oprm1 and Creb1 1 0.16 0.28 2.06
15 INT124133 Camk2a Regulation of Phosphorylation of Creb1 1 0.46 0 2
16 INT213973 Binding of Pax3 and Mthfd1 1 0.00 0.16 1.99
17 INT54488 Npepo Regulation of Gene_expression of Jun 1 0.30 0 1.98
18 INT186435 Prkcg Regulation of Creb1 1 0.44 0.45 1.9
19 INT186432 Prkaca Regulation of Creb1 1 0.14 0.45 1.9
20 INT139640 Jun Regulation of Gene_expression of Npy 1 0.21 1.98 1.75
21 INT186433 Trib3 Regulation of Phosphorylation of Creb1 1 0.03 0.32 1.71
22 INT48790 Negative_regulation of Rtcd1 Negative_regulation of Pax3 1 0.02 0 1.59
23 INT105112 Plat Positive_regulation of JUN 1 0.01 1.55 1.58
24 INT131574 Negative_regulation of Ephb1 Negative_regulation of Gene_expression of Creb1 1 0.41 0.33 1.58
25 INT114926 Creb1 Negative_regulation of Positive_regulation of Oprm1 1 0.13 0.23 1.56
26 INT256360 Car2 Positive_regulation of Localization of Rela 1 0.14 0 1.51
27 INT79021 Regulation of Binding of Jun and Fos 2 0.50 0.66 1.5
28 INT121747 Prkcg Negative_regulation of Positive_regulation of Creb1 1 0.16 0.2 1.5
29 INT121741 Prkaca Negative_regulation of Positive_regulation of Creb1 1 0.10 0.2 1.49
30 INT298283 Pou4f1 Positive_regulation of Gene_expression of Runx1 1 0.50 1.4 1.48
31 INT276687 Pax3 Positive_regulation of Nkx1-1 1 0.00 0.59 1.47
32 INT73650 Binding of Pim3 and Creb1 1 0.03 2.48 1.47
33 INT168724 Creb1 Negative_regulation of Gene_expression of Calca 1 0.46 1.09 1.38
34 INT168721 Positive_regulation of Creb1 Positive_regulation of Calca 1 0.53 1.07 1.37
35 INT106850 P2ry2 Positive_regulation of Phosphorylation of Creb1 2 0.49 0.73 1.36
36 INT168722 Creb1 Positive_regulation of Calca 1 0.73 1.05 1.35
37 INT131185 PTH Positive_regulation of Gene_expression of IGF1 3 0.44 3.31 1.31
38 INT131886 Creb1 Positive_regulation of Gene_expression of Prkcg 1 0.03 0 1.31
39 INT192080 Foxm1 Positive_regulation of Cnr1 2 0.14 0.72 1.3
40 INT148778 Binding of Usf1 and Rtn1 1 0.40 0.85 1.3
41 INT148775 Binding of Calca and Usf1 1 0.43 0.85 1.29
42 INT89878 Pdyn Positive_regulation of Gene_expression of Nkx2-5 1 0.35 0 1.29
43 INT89873 Pdyn Positive_regulation of Gene_expression of Gata4 1 0.23 0 1.29
44 INT89876 Pdyn Positive_regulation of Gata4 1 0.23 0 1.28
45 INT22501 Binding of Calca and Pth 1 0.21 0.07 1.28
46 INT124767 Creb1 Regulation of Oprm1 1 0.45 0 1.26
47 INT287104 Binding of Ntrk2 and T 1 0.20 3.29 1.26
48 INT118784 Thop1 Positive_regulation of Protein_catabolism of Pax3 1 0.07 0.07 1.25
49 INT136250 Phosphorylation of Tff3 Regulation of Creb1 1 0.02 0.18 1.24
50 INT136256 Creb1 Regulation of SGCG 1 0.26 0.18 1.23
51 INT136258 Creb1 Regulation of GRIA1 1 0.26 0.18 1.23
52 INT131195 Creb1 Positive_regulation of Positive_regulation of Drd1a 2 0.27 0.61 1.22
53 INT256298 Binding of Creb1 and Ephb1 1 0.16 1.27 1.22
54 INT298260 Binding of Runx3 and Pou4f1 1 0.52 2.08 1.22
55 INT256297 Binding of Creb1 and Insrr 1 0.00 1.22 1.19
56 INT351715 Pax3 Negative_regulation of Adarb1 1 0.00 0 1.19
57 INT256295 Binding of Creb1 and Grin2b 1 0.11 1.21 1.19
58 INT55162 Binding of NFKB1 and RELA 10 0.30 2.82 1.18
59 INT124435 Gene_expression of Chrna9 Positive_regulation of Phosphorylation of Creb1 1 0.11 0.6 1.17
60 INT189017 Binding of Pax3 and Lmna 1 0.14 0.42 1.16
61 INT48809 Pax3 Negative_regulation of Binding of Tac1 1 0.22 0 1.16
62 INT314206 Mapk14 Positive_regulation of Pax3 1 0.08 0.67 1.15
63 INT242625 Gdnf Positive_regulation of Pax3 1 0.01 0.34 1.15
64 INT147447 ADCYAP1 Regulation of Localization of RELA 1 0.50 1.12 1.15
65 INT193288 CAP1 Positive_regulation of Pth 1 0.04 0.08 1.14
66 INT294911 Pax3 Positive_regulation of Il6 1 0.06 1.78 1.14
67 INT105423 Jun Positive_regulation of Gene_expression of Penk 1 0.43 0 1.09
68 INT156462 Creb1 Regulation of Ephb1 1 0.29 0 1.07
69 INT119887 Binding of Atf4 and Usf1 1 0.21 0.15 1.05
70 INT105109 Cxcl12 Positive_regulation of JUN 1 0.01 1.07 1.05
71 INT119888 Binding of Creb1 and Usf1 1 0.18 0.15 1.05
72 INT69011 Binding of Cebpb and Nfkb1 1 0.19 0.75 1.04
73 INT307047 Foxm1 Positive_regulation of Casp3 1 0.11 0.06 1.03
74 INT117908 Em Regulation of Localization of Pax3 1 0.00 0.07 1.03
75 INT95378 Binding of Jun and Jund 5 0.20 2.06 1.02
76 INT74027 Creb1 Regulation of Jun 4 0.27 1.04 1.02
77 INT101065 MAP3K15 Positive_regulation of JUN 1 0.43 0.46 1.02
78 INT49164 Binding of Pax3 and Nka1 1 0.01 0.37 1.01
79 INT139636 Jun Negative_regulation of Phosphorylation of Npy 1 0.33 1.07 1.01
80 INT49162 Nka1 Negative_regulation of Binding of Pax3 1 0.02 0.37 1.01
81 INT113453 Ngf Positive_regulation of JUN 1 0.27 0.6 1.01
82 INT139639 Jun Negative_regulation of Positive_regulation of Vip 1 0.53 1.07 1
83 INT139643 Jun Negative_regulation of Positive_regulation of Npy 1 0.33 1.07 1
84 INT170449 Pax3 Positive_regulation of Spr 1 0.01 0.26 0.99
85 INT139641 Positive_regulation of Jun Positive_regulation of Positive_regulation of Vip 1 0.37 0.95 0.99
86 INT49163 Binding of Pax3 and Calca 1 0.03 0.37 0.98
87 INT4916 Binding of Pax3 and Wdyhv1 1 0.00 0 0.98
88 INT139642 Positive_regulation of Jun Regulation of Gene_expression of Npy 1 0.21 1.07 0.97
89 INT139638 Positive_regulation of Jun Positive_regulation of Positive_regulation of Npy 1 0.36 1.18 0.96
90 INT256357 Phosphorylation of Rela Positive_regulation of Localization of Ik 1 0.00 0.05 0.96
91 INT127263 Adra2a Regulation of Gene_expression of Jun 1 0.07 1.1 0.95
92 INT107951 Pax3 Positive_regulation of Tac1 1 0.11 1.21 0.95
93 INT148772 Usf1 Regulation of Calca 1 0.40 0.69 0.95
94 INT22726 Positive_regulation of Ahr Positive_regulation of Hrtrt1 1 0.22 0.18 0.95
95 INT22725 Ahr Positive_regulation of Hrtrt1 1 0.22 0.18 0.95
96 INT152390 Negative_regulation of Binding of JUN and OPRM1 1 0.13 0.14 0.94
97 INT152387 Binding of JUN and OPRM1 1 0.15 0.14 0.94
98 INT149390 Foxm1 Positive_regulation of Trpa1 1 0.28 0.31 0.94
99 INT82126 CEBPB Regulation of Gene_expression of Oprd1 1 0.00 0 0.93
100 INT186431 Trib3 Regulation of Creb1 1 0.03 0.23 0.92
101 INT151263 Jun Positive_regulation of S100a8 1 0.00 0.95 0.92
102 INT82120 IK Positive_regulation of CEBPB 1 0.00 0 0.92
103 INT128860 NR1H4 Negative_regulation of Gene_expression of OPRM1 1 0.15 0.31 0.92
104 INT196591 Binding of Lpar1 and Pax3 1 0.05 1.1 0.92
105 INT252879 Creb1 Positive_regulation of Gene_expression of Tacr1 1 0.03 0.24 0.91
106 INT334529 Pax3 Positive_regulation of Gene_expression of Ngf 1 0.03 0.31 0.91
107 INT219037 Creb1 Positive_regulation of Transcription of Bdnf 2 0.43 1.07 0.9
108 INT77253 Binding of gr and Creb1 1 0.03 0.4 0.9
109 INT309140 Dlat Positive_regulation of Creb1 1 0.06 1.1 0.9
110 INT249347 Binding of FOS and JUN 4 0.19 6.15 0.89
111 INT183269 Binding of CEBPB and CPOX 1 0.07 1.61 0.89
112 INT101259 Gata6 Negative_regulation of Gene_expression of ALOX15 1 0.42 0.67 0.89
113 INT142128 Nrgn Regulation of Creb1 1 0.38 0.25 0.89
114 INT14626 Binding of Dpep1 and Pax3 1 0.01 0 0.87
115 INT185329 Pax3 Positive_regulation of Gene_expression of Tg(CAG-EGFP)D4Nagy 1 0.00 0.22 0.87
116 INT73653 Binding of Creb1 and Fos 1 0.40 1.49 0.87
117 INT101258 Gene_expression of Gata6 Negative_regulation of Positive_regulation of ALOX15 1 0.42 0.65 0.87
118 INT213977 Pax3 Negative_regulation of Gene_expression of Il2 1 0.00 0.25 0.86
119 INT161308 POMC Negative_regulation of Positive_regulation of JUN 1 0.12 0.27 0.86
120 INT186672 IL8 Positive_regulation of Transcription of PTH 1 0.01 1.83 0.85
121 INT161307 JUN Positive_regulation of IL2 1 0.14 0.25 0.84
122 INT304575 Creb1 Regulation of Gene_expression of Bdnf 1 0.04 1 0.84
123 INT278690 LEF1 Negative_regulation of Gene_expression of IK 1 0.00 0.66 0.83
124 INT271193 Creb1 Regulation of Bdnf 1 0.15 0.28 0.81
125 INT193275 Phax Regulation of Pth 1 0.01 0.16 0.81
126 INT298279 Pou4f1 Positive_regulation of Gene_expression of Runx3 1 0.50 1.31 0.81
127 INT189018 Nka1 Regulation of Pax3 1 0.01 0.1 0.81
128 INT190182 JUN Positive_regulation of MMP12 1 0.34 0.08 0.8
129 INT109142 Calca Positive_regulation of Transcription of Creb1 1 0.47 0.13 0.8
130 INT182839 Camk4 Positive_regulation of Creb1 3 0.49 1.81 0.79
131 INT114924 Creb1 Regulation of Positive_regulation of Oprm1 1 0.09 0.13 0.79
132 INT186439 Prkaca Regulation of Phosphorylation of Creb1 1 0.06 0.08 0.79
133 INT131194 Creb1 Positive_regulation of Gene_expression of Pdyn 1 0.26 0.08 0.79
134 INT151807 Binding of NFATC1 and OPRM1 1 0.19 0 0.79
135 INT302831 Binding of Creb1 and Mapkapk5 1 0.07 1.3 0.79
136 INT278697 LEF1 Negative_regulation of STAT6 1 0.00 0.44 0.78
137 INT200094 Negative_regulation of Jun Negative_regulation of Gene_expression of Ptgs2 1 0.01 2.87 0.78
138 INT224280 Bdnf Positive_regulation of Creb1 3 0.30 0.62 0.77
139 INT261413 Positive_regulation of GRIN1 Positive_regulation of Positive_regulation of Creb1 1 0.00 0.81 0.77
140 INT200097 Negative_regulation of Binding of Il1a and Jun 1 0.00 2.76 0.77
141 INT90120 Jun Positive_regulation of Gene_expression of Nos1 1 0.38 0.39 0.76
142 INT106335 Olr1254 Positive_regulation of Phosphorylation of Creb1 1 0.03 0 0.76
143 INT90118 Jun Regulation of Gene_expression of Nfkb1 1 0.18 0.39 0.76
144 INT109141 Calca Positive_regulation of Creb1 1 0.47 0.13 0.76
145 INT151808 NFATC1 Positive_regulation of Positive_regulation of OPRM1 1 0.20 0 0.76
146 INT90117 Jun Regulation of Gene_expression of Nos1 1 0.21 0.39 0.76
147 INT200093 Binding of Il1a and Jun 1 0.00 2.64 0.76
148 INT262563 Negative_regulation of Pax3 Regulation of Calca 1 0.01 0.75 0.76
149 INT294908 Pax3 Positive_regulation of Gene_expression of Il1 1 0.03 0.45 0.76
150 INT90123 Jun Positive_regulation of Gene_expression of Fos 1 0.47 0.39 0.76
151 INT109143 Calca Positive_regulation of Phosphorylation of Creb1 1 0.47 0.13 0.76
152 INT262569 Pax3 Regulation of Calca 1 0.00 0.75 0.76
153 INT151809 JUN Positive_regulation of Positive_regulation of OPRM1 1 0.32 0 0.74
154 INT168420 Positive_regulation of Mapk8 Positive_regulation of Phosphorylation of Jun 1 0.30 0.88 0.74
155 INT190169 Regulation of JUN Positive_regulation of Localization of MMP12 1 0.30 0.07 0.74
156 INT106527 Akt1 Positive_regulation of Jun 1 0.05 0.53 0.74
157 INT186436 Phosphorylation of Creb1 Regulation of Transcription of Jun 1 0.21 0.44 0.73
158 INT186445 Creb1 Regulation of Transcription of FOS 1 0.49 0.44 0.73
159 INT186443 Phosphorylation of Creb1 Regulation of Transcription of FOS 1 0.49 0.44 0.73
160 INT186438 Creb1 Regulation of Transcription of Jun 1 0.21 0.44 0.73
161 INT186444 Creb1 Regulation of FOS 1 0.49 0.43 0.72
162 INT253828 Creb1 Positive_regulation of Gene_expression of Cartpt 1 0.19 0.15 0.72
163 INT228494 Binding of Ncoa5 and Rela 1 0.00 1.58 0.72
164 INT186442 Phosphorylation of Creb1 Regulation of FOS 1 0.49 0.43 0.72
165 INT186440 Phosphorylation of Creb1 Regulation of Jun 1 0.21 0.43 0.72
166 INT294906 Binding of Pax3 and Tac4 1 0.01 1.15 0.71
167 INT153123 NFKBIA Negative_regulation of Phosphorylation of RELA 1 0.03 2.01 0.71
168 INT98956 Positive_regulation of Binding of NR5A2 and SP1 1 0.00 0 0.7
169 INT98951 Positive_regulation of Binding of NR5A2 and SP3 1 0.00 0 0.7
170 INT98957 Binding of NR5A2 and SP3 1 0.00 0 0.7
171 INT98958 Binding of NR5A2 and SP1 1 0.00 0 0.7
172 INT123300 Mks1 Positive_regulation of Creb1 1 0.01 0.35 0.7
173 INT287099 Binding of Bdnf and T 1 0.10 1.1 0.69
174 INT66581 Binding of JUN and Rare2 1 0.00 0.07 0.69
175 INT303691 KNG1 Positive_regulation of AHR 1 0.03 0.98 0.69
176 INT303689 Regulation of KNG1 Positive_regulation of AHR 1 0.03 0.99 0.69
177 INT223868 Mapk1 Positive_regulation of Creb1 2 0.17 0.34 0.68
178 INT213971 Mthfd1 Positive_regulation of Gene_expression of Pax3 1 0.00 0.14 0.68
179 INT124257 Plat Positive_regulation of Jun 5 0.12 3.33 0.67
180 INT92025 Egr1 Positive_regulation of Jun 1 0.15 0.61 0.67
181 INT262570 Binding of Pax3 and Trpv1 1 0.02 1.05 0.67
182 INT298728 Akt1 Positive_regulation of Rela 1 0.01 1.03 0.67
183 INT111555 Negative_regulation of Npr1 Negative_regulation of Positive_regulation of Creb1 1 0.02 0.58 0.66
184 INT214595 Binding of FOXC1 and TIMP1 1 0.02 0.96 0.66
185 INT266064 Binding of PAG1 and Creb1 1 0.04 1.52 0.65
186 INT266049 Binding of Ceacam3 and Creb1 1 0.14 1.53 0.65
187 INT235881 Prkaca Positive_regulation of Creb1 2 0.10 0.16 0.64
188 INT148773 Binding of Calca and Usf2 1 0.46 0.42 0.64
189 INT89877 Pdyn Positive_regulation of Nkx2-5 1 0.11 0 0.64
190 INT148776 Binding of Usf2 and Rtn1 1 0.38 0.42 0.64
191 INT298262 Pou4f1 Positive_regulation of Positive_regulation of Ntrk3 1 0.36 0.79 0.63
192 INT266047 Creb1 Regulation of Ceacam3 1 0.20 1.15 0.62
193 INT186429 Camk2a Regulation of Regulation of Creb1 1 0.09 0.09 0.62
194 INT148780 Binding of Usf2 and Usf1 1 0.40 0.41 0.62
195 INT100369 HIF1A Positive_regulation of Positive_regulation of VEGFA 1 0.29 0.99 0.62
196 INT121873 Creb1 Regulation of Phosphorylation of Car2 1 0.10 0 0.62
197 INT128869 Gabrg1 Positive_regulation of Transcription of Jun 1 0.09 0.55 0.62
198 INT54487 Rabep2 Regulation of Gene_expression of Jun 1 0.06 0 0.61
199 INT177979 Binding of STAT3 and FOXI2 1 0.00 1.83 0.61
200 INT123301 Car2 Positive_regulation of Creb1 1 0.21 0.28 0.61

Single Events

The table below shows the top 100 pain related interactions that have been reported for sequence-specific distal enhancer binding RNA polymerase II transcription factor activity. They are ordered first by their pain relevance and then by number of times they were reported in sequence-specific distal enhancer binding RNA polymerase II transcription factor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT11009 Phosphorylation of Creb1 458 0.82 111.34 221.97
2 INT11012 Positive_regulation of Creb1 258 0.70 84.4 132
3 INT11011 Positive_regulation of Phosphorylation of Creb1 190 0.70 49.25 112.01
4 INT49651 Gene_expression of Creb1 276 0.78 114.77 111.96
5 INT8534 Localization of Pax3 85 0.59 28.71 82.82
6 INT57380 Phosphorylation of Creb1 213 0.82 66.8 71.26
7 INT14624 Gene_expression of Pax3 100 0.38 33.22 69.47
8 INT9484 Gene_expression of Jun 175 0.78 34.89 68.54
9 INT102020 Gene_expression of Creb1 190 0.78 57.31 59.77
10 INT82055 Positive_regulation of Creb1 176 0.70 60.2 58.39
11 INT6796 Positive_regulation of Jun 165 0.70 37.18 49.64
12 INT88617 Positive_regulation of Gene_expression of Creb1 90 0.69 51.69 44.29
13 INT4913 Binding of Pax3 52 0.28 9.57 42.67
14 INT11013 Negative_regulation of Phosphorylation of Creb1 55 0.59 18.74 34.66
15 INT666 Gene_expression of Jun 124 0.78 54.61 33.67
16 INT16714 Regulation of Creb1 64 0.62 22.23 33.56
17 INT47764 Binding of Jun 106 0.48 22.62 31.39
18 INT57379 Positive_regulation of Phosphorylation of Creb1 79 0.69 28.24 30.25
19 INT6660 Positive_regulation of Jun 148 0.69 67.58 29.73
20 INT11010 Regulation of Phosphorylation of Creb1 52 0.62 7.26 29.04
21 INT6584 Negative_regulation of Pax3 31 0.39 14.64 27.97
22 INT6624 Gene_expression of Pth 135 0.76 110.27 27.54
23 INT703 Positive_regulation of Pth 177 0.70 127.09 27.26
24 INT17331 Positive_regulation of JUN 132 0.69 60.4 27.03
25 INT28336 Positive_regulation of Pax3 37 0.33 20.94 25.66
26 INT11014 Phosphorylation of CREB1 72 0.81 26.35 25.64
27 INT102021 Positive_regulation of Gene_expression of Creb1 66 0.70 24.04 23.28
28 INT61160 Negative_regulation of Gene_expression of Creb1 37 0.59 17.95 23.17
29 INT106175 Positive_regulation of Positive_regulation of Creb1 37 0.70 13.89 22.46
30 INT61159 Regulation of Gene_expression of Creb1 46 0.62 24.07 20.52
31 INT101188 Gene_expression of Rela 81 0.56 23.43 19.15
32 INT9482 Positive_regulation of Gene_expression of Jun 60 0.69 9.95 18.61
33 INT62577 Negative_regulation of Creb1 55 0.59 19.68 18.1
34 INT61158 Negative_regulation of Creb1 33 0.59 11.54 18.06
35 INT70557 Negative_regulation of Localization of Pax3 1 0.36 1.15 17.32
36 INT102023 Regulation of Creb1 51 0.62 16.29 16.71
37 INT93482 Localization of Rela 56 0.78 24.52 14.82
38 INT105387 Gene_expression of HIF1A 116 0.77 98.62 14.66
39 INT60197 Gene_expression of JUN 90 0.78 42.32 14.61
40 INT17593 Regulation of Jun 37 0.60 5.5 14.35
41 INT107248 Negative_regulation of Gene_expression of Creb1 26 0.58 9.24 13.41
42 INT6794 Negative_regulation of Jun 37 0.53 8.04 13.37
43 INT144646 Positive_regulation of Rela 53 0.67 27.78 13.2
44 INT16713 Binding of Creb1 53 0.48 20.24 13.06
45 INT70556 Positive_regulation of Localization of Pax3 9 0.34 3.13 12.11
46 INT15756 Positive_regulation of Gene_expression of Jun 29 0.69 16.58 12.06
47 INT121223 Positive_regulation of Gene_expression of Pax3 17 0.16 4.52 12.06
48 INT70555 Regulation of Pax3 13 0.35 3.62 12.05
49 INT744 Positive_regulation of PTH 130 0.70 95.02 11.7
50 INT203473 Gene_expression of Pou4f1 69 0.76 25.94 11.36
51 INT52233 Transcription of Jun 37 0.66 6.39 11.15
52 INT15597 Negative_regulation of Gene_expression of Jun 20 0.48 6.04 11.08
53 INT62576 Transcription of Creb1 34 0.69 16.97 10.6
54 INT100379 Positive_regulation of HIF1A 69 0.69 57.31 10.4
55 INT109280 Negative_regulation of Phosphorylation of Creb1 29 0.59 11.81 10.37
56 INT60198 Binding of JUN 54 0.48 11.56 10.27
57 INT54588 Positive_regulation of CREB1 38 0.67 12.01 9.18
58 INT155944 Gene_expression of Foxp3 66 0.66 24.37 9.12
59 INT109279 Regulation of Phosphorylation of Creb1 14 0.62 4.06 8.96
60 INT22083 Regulation of Pth 55 0.62 22.32 8.9
61 INT66213 Localization of RELA 63 0.78 14.71 8.77
62 INT61264 Regulation of Jun 36 0.61 18.42 8.71
63 INT64815 Binding of Jun 49 0.48 21.47 8.59
64 INT169015 Gene_expression of FOXP3 50 0.60 33.18 8.4
65 INT93673 Transcription of Creb1 19 0.66 9.27 8.26
66 INT6625 Negative_regulation of Pth 96 0.58 57.6 8.24
67 INT53975 Positive_regulation of Binding of Jun 28 0.70 4.67 8.16
68 INT87271 Positive_regulation of Phosphorylation of CREB1 27 0.66 12.87 7.91
69 INT90603 Positive_regulation of Ahr 103 0.69 58.65 7.73
70 INT64816 Transcription of Jun 31 0.69 16.01 7.64
71 INT9476 Regulation of Gene_expression of Jun 14 0.43 4.25 7.61
72 INT14166 Positive_regulation of Ahr 32 0.61 20.78 7.47
73 INT10344 Localization of Jun 23 0.73 6.36 7.46
74 INT116619 Positive_regulation of Positive_regulation of Creb1 25 0.69 8.32 7.3
75 INT86867 Regulation of CREB1 15 0.46 4.95 7.28
76 INT75497 Regulation of JUN 28 0.61 11.04 7.09
77 INT106330 Regulation of Positive_regulation of Creb1 11 0.56 5.57 7.06
78 INT118782 Protein_catabolism of Pax3 7 0.94 0.46 6.95
79 INT53491 Negative_regulation of Jun 28 0.57 14.2 6.9
80 INT47817 Positive_regulation of Positive_regulation of Jun 21 0.66 3.7 6.83
81 INT114642 Negative_regulation of Positive_regulation of Creb1 12 0.57 2.32 6.75
82 INT68653 Negative_regulation of JUN 34 0.58 14.27 6.56
83 INT256345 Phosphorylation of Rela 21 0.75 9.51 6.56
84 INT50337 Negative_regulation of Foxm1 24 0.43 11.12 6.48
85 INT47765 Negative_regulation of Binding of Jun 21 0.43 5.05 6.38
86 INT6512 Gene_expression of PTH 103 0.77 76.29 6.33
87 INT92971 Binding of Creb1 31 0.47 11.3 6.22
88 INT4911 Negative_regulation of Binding of Pax3 7 0.22 1.89 6.17
89 INT135170 Positive_regulation of Hif1a 86 0.67 99.4 6.07
90 INT105215 Negative_regulation of Pou4f1 16 0.53 9.42 5.97
91 INT73649 Phosphorylation of Jun 28 0.80 11.01 5.87
92 INT6667 Gene_expression of CREB1 27 0.77 6.29 5.84
93 INT61986 Localization of Creb1 16 0.69 2.12 5.66
94 INT55513 Binding of Foxm1 19 0.37 2.37 5.54
95 INT112713 Gene_expression of Hif1a 24 0.75 20.48 5.45
96 INT135172 Gene_expression of Hif1a 56 0.76 46.49 5.44
97 INT93484 Negative_regulation of Positive_regulation of Jun 30 0.58 9.31 5.18
98 INT102019 Regulation of Gene_expression of Creb1 14 0.61 5.27 5.08
99 INT83735 Gene_expression of Foxm1 41 0.77 22.9 5.07
100 INT102202 Negative_regulation of Positive_regulation of Creb1 11 0.58 4.55 4.99
101 INT62570 Binding of Pth 48 0.48 26.45 4.85
102 INT203506 Positive_regulation of Pou4f1 3 0.49 6.17 4.85
103 INT106524 Phosphorylation of Jun 23 0.80 15.35 4.78
104 INT204449 Gene_expression of T 17 0.32 9.77 4.77
105 INT121866 Localization of Creb1 13 0.73 1.95 4.48
106 INT55171 Gene_expression of RELA 80 0.75 17.17 4.47
107 INT4097 Localization of Pth 66 0.81 47.17 4.36
108 INT112704 Positive_regulation of Hif1a 25 0.67 21.49 4.23
109 INT93483 Negative_regulation of Localization of Rela 11 0.57 5.1 4.19
110 INT14165 Negative_regulation of Ahr 14 0.51 8.35 4.17
111 INT67936 Transcription of JUN 18 0.52 9.52 4.13
112 INT158377 Positive_regulation of Positive_regulation of Rela 6 0.49 3.08 4.11
113 INT64163 Negative_regulation of Gene_expression of Jun 13 0.58 3.86 4.03
114 INT6661 Positive_regulation of Positive_regulation of Jun 31 0.50 7.12 3.89
115 INT105217 Regulation of Pou4f1 8 0.60 6.15 3.88
116 INT110180 Phosphorylation of JUN 23 0.80 11.21 3.83
117 INT64817 Positive_regulation of Binding of Jun 16 0.69 6.78 3.81
118 INT133550 Negative_regulation of Gene_expression of Rela 14 0.40 4.64 3.73
119 INT15776 Localization of Jun 10 0.74 3.9 3.69
120 INT76815 Regulation of Gene_expression of Pax3 4 0.12 3.81 3.65
121 INT195527 Binding of Rela 17 0.25 4.42 3.56
122 INT115921 Positive_regulation of AHR 22 0.49 12.03 3.53
123 INT23220 Positive_regulation of FOXG1 10 0.43 2.86 3.49
124 INT233640 Negative_regulation of Olig2 5 0.54 2.02 3.47
125 INT61570 Positive_regulation of Transcription of Jun 10 0.35 1.62 3.45
126 INT73557 Positive_regulation of RELA 57 0.46 8.7 3.43
127 INT170438 Negative_regulation of Gene_expression of Pax3 4 0.04 1.03 3.42
128 INT3824 Negative_regulation of PTH 40 0.59 28.58 3.39
129 INT81453 Positive_regulation of Gene_expression of JUN 18 0.50 9.39 3.23
130 INT70387 Negative_regulation of Positive_regulation of Jun 14 0.37 3.76 3.23
131 INT133557 Transcription of Rela 6 0.52 3.86 3.2
132 INT11015 Regulation of Phosphorylation of CREB1 4 0.46 1.45 3.17
133 INT147572 Gene_expression of Ahr 73 0.75 38.99 3.15
134 INT28094 Binding of PTH 29 0.37 13.57 3.09
135 INT66212 Negative_regulation of Localization of RELA 13 0.57 2.48 3.09
136 INT112365 Regulation of HIF1A 27 0.60 21.24 3.05
137 INT68651 Negative_regulation of Positive_regulation of JUN 11 0.58 4.28 3.04
138 INT47207 Negative_regulation of Ahr 25 0.52 16.11 3.02
139 INT105390 Positive_regulation of Gene_expression of HIF1A 27 0.49 26.3 2.88
140 INT9242 Negative_regulation of FOXG1 13 0.40 1.43 2.86
141 INT111554 Positive_regulation of Regulation of Creb1 4 0.50 2.12 2.85
142 INT156021 Positive_regulation of Transcription of Creb1 8 0.57 3.36 2.83
143 INT22500 Negative_regulation of Pth 6 0.43 3.41 2.83
144 INT132575 Binding of NR1H4 57 0.20 22.06 2.82
145 INT50335 Positive_regulation of Foxm1 20 0.69 5.11 2.81
146 INT44661 Regulation of Ahr 15 0.45 12.69 2.79
147 INT64819 Positive_regulation of Transcription of Jun 6 0.50 4.41 2.79
148 INT321310 Positive_regulation of Nr1h4 1 0.49 1.75 2.75
149 INT153221 Positive_regulation of Rela 5 0.16 2.16 2.72
150 INT60750 Gene_expression of HNF4A 12 0.65 8.29 2.68
151 INT134756 Positive_regulation of Gene_expression of Hif1a 8 0.50 11.14 2.68
152 INT101246 Gene_expression of Gata6 6 0.68 3.03 2.68
153 INT4114 Gene_expression of Srf 9 0.70 6.11 2.63
154 INT98919 Negative_regulation of Phosphorylation of CREB1 8 0.58 2.4 2.63
155 INT69007 Binding of Cebpb 10 0.48 2.21 2.6
156 INT194495 Regulation of Transcription of Jun 4 0.26 2.85 2.6
157 INT48807 Regulation of Binding of Pax3 2 0.13 0 2.59
158 INT188344 Positive_regulation of Gene_expression of Foxp3 10 0.36 5.97 2.56
159 INT169073 Positive_regulation of Nr1h4 8 0.47 2.44 2.45
160 INT141195 Negative_regulation of Rela 14 0.29 8.61 2.44
161 INT158666 Regulation of Transcription of Creb1 6 0.45 2.41 2.44
162 INT162518 Positive_regulation of Localization of Rela 12 0.47 1.96 2.41
163 INT121224 Positive_regulation of Positive_regulation of Pax3 5 0.14 2.32 2.4
164 INT96876 Gene_expression of AHR 20 0.77 10.43 2.39
165 INT123682 Localization of JUN 8 0.50 4.15 2.38
166 INT113203 Regulation of Foxm1 8 0.34 7.5 2.36
167 INT23219 Regulation of FOXG1 8 0.22 1.32 2.34
168 INT60199 Positive_regulation of Binding of JUN 5 0.49 1.3 2.34
169 INT22715 Positive_regulation of Gene_expression of Pth 29 0.64 22.53 2.31
170 INT70558 Regulation of Localization of Pax3 1 0.20 0.07 2.29
171 INT184932 Binding of Sry 1 0.31 2.57 2.28
172 INT2544 Localization of PTH 39 0.81 30.55 2.22
173 INT87168 Positive_regulation of Binding of Creb1 4 0.48 4.6 2.21
174 INT169072 Gene_expression of Nr1h4 7 0.60 6.23 2.18
175 INT100381 Positive_regulation of Positive_regulation of HIF1A 12 0.49 12.05 2.17
176 INT159118 Protein_catabolism of Creb1 3 0.61 0.37 2.17
177 INT106718 Regulation of Positive_regulation of Creb1 9 0.45 3.7 2.16
178 INT112364 Negative_regulation of HIF1A 22 0.57 16.95 2.13
179 INT53981 Regulation of Binding of Jun 5 0.44 0.63 2.12
180 INT59358 Regulation of Gene_expression of Jun 10 0.61 3.7 2.11
181 INT53434 Positive_regulation of T 7 0.07 3.67 2.09
182 INT13075 Binding of NKX2-1 6 0.05 0.12 2.08
183 INT132383 Gene_expression of Olig2 16 0.75 5.46 2.07
184 INT114953 Gene_expression of NR1H4 23 0.29 16.58 2.02
185 INT158442 Gene_expression of Nkx2-1 21 0.59 8.47 1.99
186 INT123530 Phosphorylation of RELA 9 0.80 3.46 1.99
187 INT110925 Positive_regulation of Positive_regulation of JUN 14 0.49 6.22 1.98
188 INT221431 Negative_regulation of FOXP3 8 0.40 9.92 1.98
189 INT96881 Gene_expression of ARNT 8 0.50 3.27 1.98
190 INT10447 Negative_regulation of Srf 3 0.40 0.95 1.98
191 INT130208 Positive_regulation of Phosphorylation of JUN 4 0.38 3.07 1.92
192 INT53982 Regulation of Positive_regulation of Jun 4 0.54 0.9 1.89
193 INT144649 Negative_regulation of Positive_regulation of Rela 11 0.26 8.27 1.87
194 INT90026 Gene_expression of FOXI2 5 0.03 0.98 1.79
195 INT280889 Gene_expression of Sox10 19 0.72 3.45 1.78
196 INT96877 Transcription of AHR 7 0.62 3.25 1.77
197 INT134197 Regulation of AHR 11 0.44 4.82 1.76
198 INT55169 Binding of RELA 40 0.36 4.91 1.74
199 INT101252 Negative_regulation of Gene_expression of Gata6 1 0.51 1.3 1.74
200 INT221426 Positive_regulation of Gene_expression of FOXP3 9 0.48 5.98 1.72
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