GO:0003720

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Name telomerase activity
Categary Function
Go Slim No
Go Link GO:0003720
Unique Molecular Interactions 71
Total Molecular Interactions 102
Total Single Events 837
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for telomerase activity. They are ordered first by their pain relevance and then by number of times they were reported for telomerase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT285939 IL6 Positive_regulation of TEP1 1 0.01 1.76 0.61
2 INT189688 PRKCA Regulation of Transcription of TERT 1 0.13 0.2 0.5
3 INT189696 PRKCA Negative_regulation of Negative_regulation of TEP1 1 0.02 0.15 0.5
4 INT189680 PRKCA Negative_regulation of TEP1 1 0.02 0.15 0.5
5 INT189675 Negative_regulation of PRKCA Negative_regulation of TEP1 1 0.02 0.15 0.5
6 INT314263 Binding of CPOX and PTGES3 1 0.01 1.7 0.44
7 INT262760 Binding of TEP1 and CD163L1 1 0.00 1.65 0.37
8 INT106511 Binding of Cpox and Ptges3 2 0.01 0.7 0.36
9 INT189687 INSRR Negative_regulation of Transcription of TERT 1 0.00 0.24 0.35
10 INT188521 Binding of Hsp90aa1 and Ptges3 1 0.02 0.61 0.33
11 INT120716 Binding of AKT1 and TEP1 1 0.05 0.46 0.21
12 INT314269 Binding of PTGES and PTGES3 1 0.12 0.68 0.18
13 INT285948 IL17A Regulation of Gene_expression of TERT 1 0.00 0.58 0.11
14 INT189702 CHKB Regulation of Gene_expression of TERT 1 0.06 0.55 0.1
15 INT285938 IL6 Positive_regulation of Gene_expression of TEP1 1 0.01 1.05 0.07
16 INT189677 CHKB Regulation of Transcription of TERT 1 0.10 1 0.05
17 INT189679 INSRR Regulation of Transcription of TERT 1 0.00 1 0.05
18 INT262781 Birc5 Regulation of TEP1 1 0.00 0.49 0.05
19 INT310727 Binding of DKC1 and TERT 1 0.23 0.91 0.05
20 INT220812 Tert Positive_regulation of Gene_expression of hl 1 0.01 0.14 0.04
21 INT220811 Tert Positive_regulation of Gene_expression of Krt36 1 0.41 0.14 0.04
22 INT220808 Tert Positive_regulation of Gene_expression of Krt31 1 0.43 0.14 0.04
23 INT285944 IL6 Positive_regulation of Gene_expression of TERT 1 0.01 0.36 0.04
24 INT296163 Mcph1 Regulation of Tert 1 0.03 0.19 0
25 INT313307 TERT Positive_regulation of NFE2L2 1 0.01 0 0
26 INT331091 Tert Positive_regulation of Positive_regulation of Cd4 1 0.24 0.76 0
27 INT189703 MZF1 Regulation of TERT 1 0.03 0.46 0
28 INT285941 IL6 Regulation of Gene_expression of TERT 1 0.01 0.12 0
29 INT220819 Myc Regulation of Transcription of Tert 1 0.44 0.1 0
30 INT347298 AREG Negative_regulation of TEP1 1 0.00 0.79 0
31 INT220813 Tert Positive_regulation of Terc 1 0.51 0.17 0
32 INT189705 INSRR Negative_regulation of Gene_expression of TERT 1 0.00 0.46 0
33 INT220817 Tert Regulation of hl 1 0.01 0.96 0
34 INT189697 INSRR Regulation of Gene_expression of TERT 1 0.00 0.46 0
35 INT270759 Binding of HSD11B1 and TERT 1 0.07 1.67 0
36 INT330956 Binding of TEP1 and NR1H4 1 0.00 1.07 0
37 INT189690 USF1 Regulation of TERT 1 0.05 0.46 0
38 INT189669 INSRR Regulation of TERT 1 0.00 0 0
39 INT189685 USF1 Positive_regulation of Transcription of TERT 1 0.05 0.27 0
40 INT189698 CHKB Regulation of TERT 1 0.06 0 0
41 INT189673 BCL2 Positive_regulation of Transcription of TERT 1 0.09 0 0
42 INT189676 CCND3 Regulation of Transcription of TERT 1 0.02 0.06 0
43 INT340917 Binding of Ptges3 and Ptplad1 1 0.14 0.17 0
44 INT347292 AREG Negative_regulation of Gene_expression of TERT 1 0.02 0.78 0
45 INT210493 Binding of HGF and TEP1 1 0.01 0.19 0
46 INT189672 Positive_regulation of INSRR Regulation of Transcription of TERT 1 0.00 0.23 0
47 INT189682 CHKB Negative_regulation of Gene_expression of TERT 1 0.10 0.46 0
48 INT220816 Tert Regulation of Myc 1 0.44 0.1 0
49 INT220809 Tert Regulation of Regulation of Myc 1 0.32 0.25 0
50 INT189684 RNF2 Regulation of TERT 1 0.02 0.46 0
51 INT210494 Binding of EGF and TEP1 1 0.02 0.19 0
52 INT330957 Binding of TEP1 and VDR 1 0.01 1.07 0
53 INT220820 Binding of Myc and Tert 1 0.26 0.19 0
54 INT313302 Regulation of TERT Positive_regulation of SQSTM1 1 0.01 0 0
55 INT285937 IL6 Regulation of TERT 1 0.01 0.12 0
56 INT313291 TERT Positive_regulation of SQSTM1 1 0.02 0 0
57 INT191413 Tert Positive_regulation of Nqo1 1 0.02 0.84 0
58 INT186989 Binding of Akt1 and Tert 1 0.00 0.61 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for telomerase activity. They are ordered first by their pain relevance and then by number of times they were reported in telomerase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT121496 Gene_expression of TERT 107 0.78 45.6 7.42
2 INT121494 Transcription of TERT 64 0.69 10.03 5.55
3 INT120717 Positive_regulation of TEP1 50 0.63 27.94 2.81
4 INT77925 Negative_regulation of TEP1 21 0.53 15.23 2.62
5 INT133194 Negative_regulation of TERT 23 0.48 4.01 2.45
6 INT106513 Gene_expression of Ptges3 7 0.73 3.57 2.42
7 INT189770 Positive_regulation of Transcription of TERT 1 0.28 1.36 2.14
8 INT189766 Regulation of Transcription of TERT 1 0.25 3.48 1.99
9 INT86368 Gene_expression of TEP1 31 0.50 16.36 1.63
10 INT147403 Regulation of Gene_expression of TERT 11 0.27 3.45 1.54
11 INT220783 Gene_expression of Tert 39 0.77 12.55 1.49
12 INT129712 Positive_regulation of Gene_expression of TERT 12 0.70 7.3 1.44
13 INT133193 Positive_regulation of TERT 16 0.50 6.43 1.38
14 INT147607 Binding of TERT 16 0.48 12.36 1.31
15 INT189736 Regulation of TERT 22 0.40 3.58 1.29
16 INT38916 Positive_regulation of Tert 3 0.33 1.92 1.28
17 INT139886 Gene_expression of PTGES3 11 0.72 1.5 1.27
18 INT133195 Negative_regulation of Transcription of TERT 4 0.42 2.9 1.08
19 INT71314 Regulation of Ptges3 1 0.13 0.84 1.02
20 INT117581 Positive_regulation of Gene_expression of Ptges3 1 0.39 0.93 0.93
21 INT117584 Regulation of Gene_expression of Ptges3 1 0.21 0.93 0.93
22 INT189734 Negative_regulation of Gene_expression of TERT 8 0.24 1.84 0.85
23 INT184157 Gene_expression of Ptges3 6 0.45 2.93 0.71
24 INT94896 Regulation of TEP1 12 0.39 8.04 0.69
25 INT117583 Positive_regulation of Ptges3 1 0.36 0.59 0.57
26 INT130507 Negative_regulation of Ptges3 1 0.35 0.81 0.53
27 INT189756 Positive_regulation of Phosphorylation of TERT 1 0.28 0.2 0.5
28 INT189722 Regulation of Positive_regulation of TEP1 1 0.03 0.2 0.5
29 INT189728 Phosphorylation of TERT 1 0.34 0.2 0.5
30 INT220787 Localization of Tert 5 0.69 0.87 0.49
31 INT189757 Negative_regulation of Gene_expression of TEP1 3 0.05 2.09 0.48
32 INT139890 Regulation of Gene_expression of PTGES3 2 0.50 0.82 0.43
33 INT310728 Binding of DKC1 1 0.25 2.36 0.38
34 INT189763 Positive_regulation of Transcription of TEP1 1 0.06 0.38 0.36
35 INT189760 Negative_regulation of Negative_regulation of TERT 1 0.24 0.11 0.34
36 INT189739 Negative_regulation of Regulation of TERT 1 0.18 0.17 0.32
37 INT220770 Binding of Tert 7 0.37 1.09 0.27
38 INT220785 Positive_regulation of Tert 15 0.68 6.9 0.25
39 INT310797 Positive_regulation of Gene_expression of PTGES3 1 0.17 0.7 0.23
40 INT310800 Positive_regulation of PTGES3 1 0.24 0.7 0.23
41 INT189768 Positive_regulation of Positive_regulation of TEP1 5 0.44 1.56 0.21
42 INT252169 Negative_regulation of Gene_expression of Ptges3 1 0.16 0.5 0.21
43 INT220777 Positive_regulation of Gene_expression of Tert 9 0.68 2.34 0.18
44 INT189732 Transcription of TEP1 1 0.09 0.19 0.18
45 INT220767 Regulation of Tert 1 0.53 1 0.16
46 INT220774 Negative_regulation of Gene_expression of Tert 1 0.58 1.09 0.14
47 INT189761 Positive_regulation of Regulation of TERT 1 0.19 0.14 0.14
48 INT189767 Positive_regulation of Gene_expression of TEP1 4 0.30 1.43 0.11
49 INT178215 Binding of TEP1 2 0.06 1.05 0.11
50 INT186980 Transcription of Tert 1 0.34 0.34 0.11
51 INT186973 Regulation of Transcription of Tert 1 0.21 0.34 0.11
52 INT210506 Negative_regulation of Positive_regulation of TEP1 3 0.28 1.76 0.08
53 INT220780 Regulation of Gene_expression of Tert 1 0.44 0 0.08
54 INT189740 Regulation of Gene_expression of TEP1 1 0.06 0.48 0.05
55 INT186977 Gene_expression of Tert 1 0.36 1.49 0.05
56 INT220784 Regulation of Regulation of Tert 1 0.39 0 0.04
57 INT220786 Negative_regulation of Tert 8 0.43 2.55 0.03
58 INT310796 Transcription of PTGES3 1 0.27 0.05 0.03
59 INT274377 Localization of TERT 3 0.70 0.78 0
60 INT220792 Transcription of Tert 2 0.71 0.56 0
61 INT223278 Positive_regulation of Binding of TERT 2 0.44 1.35 0
62 INT186978 Positive_regulation of Positive_regulation of Tert 1 0.22 0.44 0
63 INT186985 Positive_regulation of Transcription of Tert 1 0.24 0 0
64 INT186976 Binding of Tert 1 0.17 0.55 0
65 INT347316 Negative_regulation of Binding of TERT 1 0.18 0.26 0
66 INT189751 Regulation of Regulation of TERT 1 0.11 0.08 0
67 INT331373 Positive_regulation of Transcription of Tert 1 0.24 0.17 0
68 INT260376 Protein_catabolism of TERT 1 0.02 0.36 0
69 INT186974 Negative_regulation of Transcription of Tert 1 0.27 0 0
70 INT189772 Positive_regulation of Regulation of TEP1 1 0.06 0.08 0
71 INT310726 Localization of Terc 1 0.24 0.27 0
72 INT302873 Regulation of DKC1 1 0.37 0.05 0
73 INT189744 Regulation of Regulation of TEP1 1 0.03 0.08 0
74 INT186988 Negative_regulation of Gene_expression of Tert 1 0.27 1.06 0
75 INT186986 Negative_regulation of Tert 1 0.27 0.61 0
76 INT338717 Gene_expression of DKC1 1 0.01 0.41 0
77 INT310799 Negative_regulation of Gene_expression of PTGES3 1 0.17 0 0
78 INT186987 Regulation of Tert 1 0.13 0 0
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