GO:0003726

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Name double-stranded RNA adenosine deaminase activity
Categary Function
Go Slim No
Go Link GO:0003726
Unique Molecular Interactions 319
Total Molecular Interactions 458
Total Single Events 3277
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for double-stranded RNA adenosine deaminase activity. They are ordered first by their pain relevance and then by number of times they were reported for double-stranded RNA adenosine deaminase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT9546 Binding of Adarb1 and Penk 5 0.03 0 5.1
2 INT107331 Binding of PPBP and Adarb1 1 0.01 0 3.67
3 INT128513 Pnoc Regulation of Adarb1 1 0.01 0.92 3.14
4 INT298456 Prkaca Positive_regulation of Phosphorylation of Adarb1 1 0.00 1.86 2.85
5 INT164665 Adarb1 Positive_regulation of Negative_regulation of Tens1 1 0.03 0.42 1.97
6 INT30146 Binding of Adarb1 and Pdyn 1 0.01 0.17 1.91
7 INT151889 Binding of Adarb1 and DLL1 1 0.00 0 1.66
8 INT67966 Cck Positive_regulation of Adarb1 2 0.03 0 1.63
9 INT94033 Binding of Adarb1 and SLAMF6 1 0.01 0 1.61
10 INT128512 Regulation of Pnoc Regulation of Adarb1 1 0.01 0.46 1.58
11 INT72319 Adarb1 Positive_regulation of Gene_expression of Fos 3 0.10 0.1 1.44
12 INT298458 Binding of Calcrl and Adarb1 1 0.00 0.23 1.41
13 INT73377 Npy Regulation of Adarb1 2 0.03 0.15 1.38
14 INT29599 Binding of Cyp21a1 and Adarb1 1 0.01 0 1.38
15 INT94630 Positive_regulation of Adarb1 Positive_regulation of Gene_expression of Fos 2 0.03 0.1 1.32
16 INT112097 Sstr1 Positive_regulation of Adarb1 1 0.02 0.15 1.29
17 INT298454 Prkcg Positive_regulation of Phosphorylation of Adarb1 1 0.00 0.41 1.19
18 INT109380 Binding of Adarb1 and Fos 1 0.02 0.38 1.19
19 INT351715 Pax3 Negative_regulation of Adarb1 1 0.00 0 1.19
20 INT73075 Adarb1 Regulation of Fos 1 0.01 0.07 1.18
21 INT32871 Binding of Insrr and Adarb1 1 0.01 0 1.18
22 INT21331 Binding of Adarb1 and Gm5195 1 0.00 0.26 1.08
23 INT33338 Adarb1 Positive_regulation of Localization of Gh1 1 0.04 0 1.08
24 INT33336 Adarb1 Positive_regulation of Negative_regulation of Gh1 1 0.03 0 1.08
25 INT33337 Adarb1 Positive_regulation of Gh1 1 0.03 0 1.08
26 INT121089 Binding of Oprd1 and Adarb1 2 0.06 0 1.07
27 INT132701 Adarb1 Negative_regulation of Gene_expression of Fos 1 0.01 0.73 1.07
28 INT57509 Trh Negative_regulation of Adarb1 1 0.02 0.22 1.05
29 INT57508 Pomc Negative_regulation of Adarb1 1 0.01 0.22 1.05
30 INT71000 Positive_regulation of Adarb1 Positive_regulation of Odc1 1 0.01 0 1
31 INT162299 Negative_regulation of Adarb1 Negative_regulation of Gene_expression of Calca 1 0.01 0.93 1
32 INT123023 Ednra Regulation of Adarb1 1 0.00 0 0.93
33 INT86350 Negative_regulation of Adarb1 Negative_regulation of Positive_regulation of Fos 1 0.04 0.8 0.92
34 INT113542 Binding of Calca and Adarb1 2 0.00 0.44 0.85
35 INT41108 Adarb1 Positive_regulation of Localization of Ins1 1 0.03 0 0.81
36 INT70422 Binding of Htr1a and Adarb1 1 0.01 0.37 0.81
37 INT61052 Binding of Adarb1 and Negative_regulation of Gene_expression of Odc1 1 0.02 0 0.81
38 INT322397 Egfr Positive_regulation of Adarb1 1 0.00 0.08 0.8
39 INT111129 Adarb1 Regulation of Gene_expression of Fos 1 0.09 0 0.79
40 INT96307 Binding of Pnoc and Adarb1 1 0.12 0.37 0.77
41 INT73087 Adarb1 Positive_regulation of Fos 1 0.02 0 0.76
42 INT13344 Binding of Npy and Adarb1 2 0.02 0.41 0.73
43 INT72318 Adarb1 Positive_regulation of Positive_regulation of Cck 1 0.04 0 0.72
44 INT83714 Adarb1 Positive_regulation of Localization of Sst 1 0.00 0.9 0.72
45 INT314593 Zbp1 Negative_regulation of Gene_expression of Isg15 1 0.28 0.17 0.7
46 INT314589 Zbp1 Negative_regulation of Gene_expression of Oasl1 1 0.31 0.17 0.7
47 INT314595 Zbp1 Negative_regulation of Gene_expression of Samhd1 1 0.05 0.17 0.7
48 INT107330 Binding of Adarb1 and Trh 1 0.01 0 0.65
49 INT124904 Binding of Tacr1 and Adarb1 2 0.01 0.5 0.63
50 INT52478 Binding of Adarb1 and Ift172 1 0.00 0 0.62
51 INT53312 Adarb1 Regulation of Regulation of Cfp 1 0.02 0.2 0.6
52 INT133500 Calca Negative_regulation of Adarb1 1 0.02 0.26 0.59
53 INT59635 Binding of Adarb1 and Gnaz 1 0.01 0 0.55
54 INT69178 Binding of SLC3A2 and Adarb1 1 0.00 0.16 0.53
55 INT69179 Binding of UBA7 and Adarb1 1 0.00 0.16 0.53
56 INT93616 Binding of Adarb1 and Ngf 1 0.08 0.6 0.51
57 INT73056 Binding of Hrh1 and Adarb1 1 0.00 0.25 0.49
58 INT110300 Cartpt Regulation of Adarb1 1 0.14 0 0.49
59 INT151890 Binding of PRLR and Adarb1 1 0.00 0 0.45
60 INT142171 Positive_regulation of Adarb1 Positive_regulation of Apcs 1 0.01 0.19 0.43
61 INT309199 Abat Positive_regulation of Adarb1 1 0.00 0 0.42
62 INT73453 Negative_regulation of Adarb1 Negative_regulation of Gene_expression of Fos 1 0.02 0 0.42
63 INT36783 Binding of Cck and Adarb1 1 0.27 0 0.41
64 INT272363 Binding of Adar and Adarb1 3 0.26 0.76 0.36
65 INT4638 Binding of Agt and Adarb1 3 0.01 0 0.34
66 INT26071 Adarb1 Regulation of Localization of Crh 1 0.01 0.21 0.32
67 INT107944 Crh Regulation of Adarb1 1 0.06 0 0.32
68 INT71519 Edn1 Positive_regulation of Gene_expression of Adarb1 1 0.02 0.48 0.31
69 INT342810 Binding of Adarb1 and Gsk3b 1 0.00 0.36 0.3
70 INT107943 IgG-2a Positive_regulation of Adarb1 1 0.04 0 0.3
71 INT65523 Binding of Adarb1 and Oprl1 1 0.02 0 0.28
72 INT83540 Cck Regulation of Adarb1 1 0.01 0.06 0.26
73 INT51045 Adarb1 Regulation of Localization of Pgc 1 0.01 0 0.25
74 INT136492 Binding of Adarb1 and Sigmar1 1 0.03 0.1 0.21
75 INT343841 ZBP1 Regulation of Transcription of IFN1@ 1 0.00 0.2 0.19
76 INT272365 Gene_expression of Adarb1 Positive_regulation of Gene_expression of GRIA1 1 0.00 0.26 0.09
77 INT227303 Zbp1 Regulation of Transcription of Baat 1 0.09 1.43 0.08
78 INT113369 Edn1 Regulation of Adarb1 1 0.02 0.14 0.08
79 INT227301 Zbp1 Regulation of Transcription of Ucp1 1 0.19 1.42 0.08
80 INT227304 Zbp1 Regulation of Transcription of Ucp2 1 0.17 1.43 0.08
81 INT351760 Adarb1 Regulation of Gria2 1 0.30 1.7 0.07
82 INT13343 Binding of Pomc and Adarb1 1 0.00 0.31 0.03
83 INT227305 Zbp1 Regulation of Gene_expression of Adipoq 1 0.21 1.27 0
84 INT227302 Zbp1 Regulation of Transcription of Adipoq 1 0.09 1.27 0
85 INT272364 Gene_expression of Adar Negative_regulation of Adarb1 1 0.31 0.17 0
86 INT210873 Binding of Ntrk2 and Adarb1 1 0.00 0 0
87 INT281718 Binding of Adar and Adarb2 1 0.11 0.21 0
88 INT351761 Adar Negative_regulation of Gene_expression of Adarb1 1 0.27 0.8 0
89 INT351762 Adarb1 Regulation of Car2 1 0.11 0.68 0
90 INT341628 Binding of ADAR and PROC 1 0.03 5.01 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for double-stranded RNA adenosine deaminase activity. They are ordered first by their pain relevance and then by number of times they were reported in double-stranded RNA adenosine deaminase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT12501 Positive_regulation of Adarb1 166 0.58 36.94 118.92
2 INT6214 Negative_regulation of Adarb1 123 0.50 26.39 89.57
3 INT4637 Binding of Adarb1 132 0.41 14.48 67.76
4 INT6165 Gene_expression of Adarb1 85 0.58 18.39 51.03
5 INT12502 Regulation of Adarb1 50 0.53 7.58 30.01
6 INT21072 Localization of Adarb1 26 0.69 2.76 17.95
7 INT18616 Positive_regulation of Positive_regulation of Adarb1 18 0.33 2.04 13.18
8 INT113765 Phosphorylation of Adarb1 10 0.05 4.91 10.51
9 INT21435 Positive_regulation of Negative_regulation of Adarb1 7 0.39 3.13 6.5
10 INT14159 Negative_regulation of Positive_regulation of Adarb1 8 0.08 2.06 5.14
11 INT25796 Regulation of Gene_expression of Adarb1 6 0.26 2.77 4.3
12 INT80902 Negative_regulation of Gene_expression of Adarb1 4 0.25 1.82 3.56
13 INT9578 Regulation of Binding of Adarb1 4 0.09 0.21 3.37
14 INT272358 Gene_expression of Adarb1 19 0.73 26.94 3.11
15 INT113768 Positive_regulation of Phosphorylation of Adarb1 3 0.04 1.37 3.02
16 INT16773 Negative_regulation of Binding of Adarb1 7 0.37 0 2.48
17 INT64543 Transcription of Adarb1 4 0.59 0 2.43
18 INT43958 Positive_regulation of Zbp1 6 0.52 1.54 2.3
19 INT76008 Positive_regulation of ADAR 7 0.60 2.24 2
20 INT34287 Regulation of Positive_regulation of Adarb1 3 0.10 0.47 1.8
21 INT144099 Gene_expression of Zbp1 6 0.51 4.55 1.6
22 INT43960 Negative_regulation of Zbp1 4 0.37 0.88 1.58
23 INT57866 Positive_regulation of Gene_expression of Adarb1 2 0.04 0.25 1.44
24 INT163133 Gene_expression of ZBP1 28 0.65 18.59 1.25
25 INT72321 Regulation of Negative_regulation of Adarb1 2 0.07 0.15 1.22
26 INT75893 Negative_regulation of Localization of Adarb1 1 0.33 0.51 1.2
27 INT272347 Positive_regulation of Gene_expression of Adarb1 9 0.65 4.43 1.15
28 INT154275 Regulation of Regulation of Adarb1 1 0.03 1.23 1.04
29 INT322390 Protein_catabolism of Adarb1 1 0.01 0 1.02
30 INT272351 Regulation of Adar 5 0.50 1.56 0.99
31 INT65934 Negative_regulation of Negative_regulation of Adarb1 1 0.02 0 0.94
32 INT272350 Regulation of Adarb1 4 0.48 5.85 0.9
33 INT313713 Positive_regulation of Regulation of Adar 1 0.41 0 0.84
34 INT51623 Positive_regulation of Binding of Adarb1 2 0.03 0 0.81
35 INT272331 Negative_regulation of Gene_expression of Adarb1 2 0.55 9.6 0.73
36 INT272360 Gene_expression of Adar 13 0.61 4.33 0.69
37 INT55049 Regulation of Localization of Adarb1 1 0.02 0 0.67
38 INT47671 Positive_regulation of Localization of Adarb1 1 0.01 0 0.58
39 INT43959 Negative_regulation of Positive_regulation of Zbp1 1 0.27 0 0.51
40 INT272342 Regulation of Gene_expression of Adarb1 5 0.58 5.72 0.5
41 INT272362 Binding of Adarb1 8 0.38 0.84 0.46
42 INT29058 Localization of ADAR 2 0.75 3.88 0.46
43 INT355451 Regulation of Binding of ZBP1 1 0.03 0.53 0.46
44 INT355453 Binding of ZBP1 1 0.02 0.53 0.46
45 INT355452 Regulation of ZBP1 1 0.03 0.53 0.46
46 INT113767 Regulation of Phosphorylation of Adarb1 1 0.03 0 0.46
47 INT272338 Negative_regulation of Adarb1 4 0.46 8.88 0.43
48 INT272348 Binding of Adar 8 0.38 1.01 0.36
49 INT272330 Positive_regulation of Adar 2 0.34 0.05 0.33
50 INT81659 Negative_regulation of ZBP1 1 0.10 0.12 0.33
51 INT272349 Positive_regulation of Adarb1 6 0.44 1.76 0.3
52 INT272357 Localization of Adarb1 7 0.63 0.35 0.24
53 INT134582 Localization of Zbp1 1 0.51 0 0.22
54 INT319339 Localization of ZBP1 3 0.18 3.09 0.2
55 INT272332 Positive_regulation of Localization of Adarb1 2 0.54 0.15 0.19
56 INT314564 Positive_regulation of Positive_regulation of Zbp1 1 0.38 0.07 0.19
57 INT272343 Transcription of Adarb1 4 0.64 1.94 0.18
58 INT131128 Gene_expression of ADAR 4 0.59 4.3 0.16
59 INT272329 Positive_regulation of Transcription of Adarb1 1 0.54 0.2 0.15
60 INT272352 Negative_regulation of Positive_regulation of Adarb1 1 0.29 0.2 0.15
61 INT272354 Regulation of Gene_expression of Adar 1 0.49 0.31 0.14
62 INT77498 Positive_regulation of ZBP1 2 0.40 1.59 0.09
63 INT341630 Regulation of ADAR 1 0.24 0.4 0.05
64 INT272344 Transcription of Adar 4 0.57 1.85 0.04
65 INT352834 Protein_catabolism of Adar 1 0.56 0.15 0.04
66 INT227276 Regulation of Zbp1 1 0.17 2.25 0.04
67 INT272346 Regulation of Transcription of Adar 2 0.36 0.96 0
68 INT337457 Phosphorylation of ADAR 2 0.71 0.69 0
69 INT337479 Binding of ADAR 2 0.37 1.3 0
70 INT272335 Positive_regulation of Transcription of Adar 1 0.40 0 0
71 INT351755 Regulation of Transcription of Adarb1 1 0.42 0.86 0
72 INT351754 Negative_regulation of Gene_expression of Adar 1 0.39 1.78 0
73 INT320831 Positive_regulation of Gene_expression of ZBP1 1 0.01 2.85 0
74 INT272359 Positive_regulation of Gene_expression of Adar 1 0.55 1.47 0
75 INT351756 Positive_regulation of Regulation of Adarb1 1 0.47 1.35 0
76 INT337477 Positive_regulation of Phosphorylation of ADAR 1 0.06 0.28 0
77 INT351753 Negative_regulation of Transcription of Adar 1 0.28 0.91 0
78 INT131129 Negative_regulation of ADAR 1 0.58 0 0
79 INT272337 Positive_regulation of Binding of Adar 1 0.40 0 0
80 INT351752 Regulation of Regulation of Adarb1 1 0.42 0.76 0
81 INT337463 Negative_regulation of Positive_regulation of ADAR 1 0.07 0.26 0
82 INT272341 Positive_regulation of Binding of Adarb1 1 0.39 0 0
83 INT337468 Positive_regulation of Binding of ADAR 1 0.08 0 0
84 INT351757 Negative_regulation of Transcription of Adarb1 1 0.40 0.9 0
85 INT272336 Localization of Adar 1 0.63 0.12 0
86 INT351758 Regulation of Positive_regulation of Adarb1 1 0.25 1.23 0
87 INT272361 Negative_regulation of Adar 1 0.40 0.37 0
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