GO:0003730

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Name mRNA 3'-UTR binding
Categary Function
Go Slim No
Go Link GO:0003730
Unique Molecular Interactions 47
Total Molecular Interactions 61
Total Single Events 410
Pain Genes Associated 13

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for mRNA 3'-UTR binding. They are ordered first by their pain relevance and then by number of times they were reported for mRNA 3'-UTR binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT327333 Binding of TNF and Fxr1 1 0.06 3.74 0.48
2 INT229292 FXR1 Regulation of Gene_expression of FGF19 1 0.08 1.14 0.37
3 INT327308 Binding of Elavl1 and Ttpa 1 0.02 1.73 0.34
4 INT270276 Binding of NPBWR1 and CPSF1 1 0.02 0 0.33
5 INT327328 Binding of Hnrnpd and Elavl1 1 0.06 0.74 0.3
6 INT327321 Binding of Elavl1 and Nos2 1 0.05 0.6 0.24
7 INT327320 Positive_regulation of Binding of Elavl1 and Nos2 1 0.06 0.6 0.24
8 INT327313 Positive_regulation of Mapk14 Positive_regulation of Phosphorylation of Khsrp 1 0.09 0.24 0.22
9 INT327315 S100a8 Negative_regulation of Binding of Khsrp 1 0.01 0.55 0.21
10 INT221955 Binding of ELAVL1 and CDK5R1 1 0.01 0.93 0.19
11 INT327317 Ttpa Negative_regulation of Elavl1 1 0.02 0.45 0.19
12 INT327312 Positive_regulation of Ttpa Negative_regulation of Elavl1 1 0.03 0.45 0.19
13 INT350702 Rc3h1 Positive_regulation of Protein_catabolism of Icos 1 0.35 1.56 0.18
14 INT327310 Binding of Ccnd1 and Elavl1 1 0.04 0.38 0.16
15 INT327316 Binding of Elavl1 and Khsrp 1 0.12 0.36 0.14
16 INT327318 Mapk14 Regulation of Localization of Elavl1 1 0.09 0.42 0.13
17 INT350694 Uts2r Negative_regulation of Negative_regulation of Rc3h1 1 0.05 0.79 0.1
18 INT229286 BAS Negative_regulation of FXR1 1 0.02 0.55 0.09
19 INT210288 Binding of CD8A and ELAVL4 1 0.27 1.21 0.07
20 INT229288 Binding of FXR1 and BAS 1 0.01 0.59 0.05
21 INT229331 Binding of FXR1 and Nr1h2 1 0.02 0.61 0.05
22 INT229293 Positive_regulation of FXR1 Positive_regulation of Gene_expression of NR0B2 1 0.02 0.59 0.04
23 INT327336 Binding of VEGFA and Elavl1 1 0.06 0.94 0.04
24 INT221963 ELAVL1 Regulation of Gene_expression of CDK5R1 1 0.01 0.58 0.03
25 INT260948 Khsrp Negative_regulation of Binding of Elavl1 1 0.24 0.11 0.03
26 INT221961 Binding of ELAVL1 and UTS2R 1 0.00 0.26 0.03
27 INT260946 Zfp36 Negative_regulation of Binding of Elavl1 1 0.21 0.11 0.03
28 INT221960 Binding of C4B and ELAVL1 1 0.00 0.15 0
29 INT300901 Binding of IGF2 and IGF2BP1 1 0.04 0.71 0
30 INT287606 Binding of Fxr1 and Fxr2 1 0.32 0 0
31 INT287610 Binding of Fmr1 and Fxr1 1 0.46 0 0
32 INT287611 Fmr1 Regulation of Gene_expression of Fxr1 1 0.38 0 0
33 INT287615 Ap3b1 Regulation of Binding of Fxr1 1 0.00 0 0
34 INT300899 IGF2BP3 Positive_regulation of IGF2 1 0.37 1.06 0
35 INT210286 Binding of ELAVL4 and GOPC 1 0.06 0.87 0
36 INT246912 Binding of Ifng and Igf2bp2 1 0.01 0.6 0
37 INT300900 Binding of MYC and IGF2BP1 1 0.06 0.71 0
38 INT287617 Ap3b1 Regulation of Fxr1 1 0.00 0 0
39 INT295871 Binding of RNPS1 and Srpk2 1 0.01 0.76 0
40 INT327341 VEGFA Regulation of Elavl1 1 0.08 1.27 0
41 INT287614 Fxr2 Regulation of Gene_expression of Fxr1 1 0.24 0 0
42 INT162436 Binding of Igfals and Tardbp 1 0.16 2.68 0
43 INT300898 IGF2BP3 Regulation of Gene_expression of IGF2 1 0.21 0.38 0
44 INT327335 VEGFA Regulation of Binding of Elavl1 1 0.08 1.27 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for mRNA 3'-UTR binding. They are ordered first by their pain relevance and then by number of times they were reported in mRNA 3'-UTR binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT149642 Binding of Elavl1 5 0.23 5.49 1.59
2 INT149646 Gene_expression of Elavl1 2 0.44 18.47 1.34
3 INT149644 Positive_regulation of Gene_expression of Elavl1 2 0.32 13.13 1.27
4 INT260901 Localization of Elavl1 2 0.47 8.78 1.18
5 INT229302 Positive_regulation of FXR1 1 0.14 3.36 1.15
6 INT303287 Gene_expression of Tardbp 4 0.77 44.78 1.09
7 INT260905 Phosphorylation of Khsrp 2 0.52 2.3 1
8 INT124314 Gene_expression of IGF2BP3 7 0.77 33.13 0.97
9 INT229328 Negative_regulation of FXR1 1 0.12 2.67 0.96
10 INT260921 Negative_regulation of Khsrp 2 0.34 3.12 0.94
11 INT292763 Localization of Tardbp 6 0.80 12.51 0.91
12 INT327232 Positive_regulation of Transcription of Elavl1 1 0.23 2.79 0.89
13 INT327280 Positive_regulation of Elavl1 1 0.23 3.3 0.66
14 INT327287 Transcription of Elavl1 1 0.31 2.11 0.64
15 INT229305 Gene_expression of FXR1 1 0.13 3.26 0.63
16 INT260906 Binding of Khsrp 2 0.30 1.48 0.57
17 INT210300 Gene_expression of ELAVL4 10 0.65 5.14 0.49
18 INT35619 Positive_regulation of Localization of RNPS1 1 0.01 0 0.49
19 INT204452 Binding of Fxr1 10 0.40 4.48 0.45
20 INT124313 Positive_regulation of Gene_expression of IGF2BP3 4 0.69 8.07 0.45
21 INT335733 Positive_regulation of Tardbp 8 0.69 28.41 0.41
22 INT260917 Positive_regulation of Localization of Elavl1 2 0.32 4.1 0.41
23 INT229308 Positive_regulation of Gene_expression of FXR1 1 0.10 1.39 0.41
24 INT327228 Phosphorylation of Elavl1 1 0.38 2.07 0.4
25 INT260916 Regulation of Elavl1 2 0.21 2.47 0.38
26 INT327234 Negative_regulation of Elavl1 1 0.20 3.04 0.37
27 INT270285 Binding of CPSF1 1 0.02 0 0.33
28 INT335118 Regulation of FXR1 1 0.03 0.1 0.32
29 INT335110 Regulation of Regulation of FXR1 1 0.03 0.1 0.32
30 INT85944 Binding of ELAVL1 5 0.07 1.11 0.31
31 INT292766 Negative_regulation of Localization of Tardbp 1 0.07 0.75 0.29
32 INT124315 Negative_regulation of IGF2BP3 1 0.11 1.48 0.26
33 INT335724 Positive_regulation of Localization of Tardbp 3 0.47 4.9 0.25
34 INT260918 Regulation of Khsrp 2 0.28 1.33 0.25
35 INT229321 Negative_regulation of Gene_expression of FXR1 1 0.08 0.23 0.25
36 INT35618 Localization of RNPS1 1 0.01 0 0.24
37 INT3239 Negative_regulation of ELAVL1 1 0.41 0.25 0.22
38 INT327268 Regulation of Phosphorylation of Elavl1 1 0.28 1.02 0.21
39 INT327281 Positive_regulation of Phosphorylation of Khsrp 1 0.29 0.23 0.21
40 INT327290 Negative_regulation of Binding of Khsrp 1 0.27 0.54 0.21
41 INT292764 Negative_regulation of Tardbp 2 0.58 2.59 0.19
42 INT327279 Regulation of Gene_expression of Elavl1 1 0.21 0.85 0.16
43 INT210296 Positive_regulation of ELAVL4 1 0.36 1.51 0.15
44 INT344990 Binding of Tardbp 1 0.37 3.5 0.15
45 INT210297 Binding of ELAVL4 1 0.24 1.29 0.11
46 INT229327 Positive_regulation of Positive_regulation of FXR1 1 0.10 0.92 0.11
47 INT300912 Transcription of IGF2BP3 1 0.62 1.4 0.1
48 INT300904 Positive_regulation of Transcription of IGF2BP3 1 0.46 0.94 0.1
49 INT350668 Positive_regulation of Rc3h1 1 0.49 0.79 0.1
50 INT350640 Negative_regulation of Rc3h1 1 0.41 0.73 0.1
51 INT124312 Negative_regulation of Gene_expression of IGF2BP3 1 0.12 0.83 0.09
52 INT202702 Binding of IGF2BP3 2 0.36 3.82 0.08
53 INT210298 Positive_regulation of Phosphorylation of ELAVL4 1 0.36 0.39 0.08
54 INT210299 Phosphorylation of ELAVL4 1 0.59 0.39 0.08
55 INT229309 Binding of FXR1 1 0.07 0.58 0.05
56 INT229303 Localization of FXR1 1 0.14 0.6 0.05
57 INT344991 Negative_regulation of Positive_regulation of Tardbp 1 0.43 0.81 0.05
58 INT295864 Phosphorylation of RNPS1 1 0.02 0.81 0.04
59 INT327286 Regulation of Binding of Khsrp 1 0.28 0.05 0.04
60 INT187927 Negative_regulation of CPSF1 1 0.00 0.15 0.03
61 INT327252 Negative_regulation of Gene_expression of Elavl1 1 0.19 0.81 0.03
62 INT287572 Positive_regulation of Fxr1 1 0.42 0.07 0.03
63 INT303295 Regulation of Tardbp 2 0.45 4.74 0
64 INT284795 Positive_regulation of IGF2BP3 2 0.50 1.19 0
65 INT303284 Regulation of Gene_expression of Tardbp 2 0.45 6.82 0
66 INT344986 Regulation of Positive_regulation of Tardbp 1 0.39 0.98 0
67 INT221979 Regulation of ELAVL1 1 0.01 0 0
68 INT246906 Gene_expression of Igf2bp2 1 0.26 0.8 0
69 INT300905 Regulation of IGF2BP3 1 0.45 0.37 0
70 INT287589 Regulation of Binding of Fxr1 1 0.37 0 0
71 INT344999 Protein_catabolism of Tardbp 1 0.66 1.18 0
72 INT246908 Binding of Igf2bp2 1 0.15 1.96 0
73 INT344996 Negative_regulation of Gene_expression of Tardbp 1 0.43 0.73 0
74 INT300913 Regulation of Regulation of IGF2BP3 1 0.45 0.37 0
75 INT295861 Binding of RNPS1 1 0.01 0.76 0
76 INT287591 Gene_expression of Fxr1 1 0.64 0 0
77 INT287596 Negative_regulation of Fxr1 1 0.36 0 0
78 INT300909 Regulation of Gene_expression of IGF2BP3 1 0.61 1.77 0
79 INT246903 Positive_regulation of Gene_expression of Igf2bp2 1 0.20 0.8 0
80 INT287575 Localization of Fxr1 1 0.62 0 0
81 INT344988 Positive_regulation of Gene_expression of Tardbp 1 0.47 3.29 0
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