GO:0003746

From wiki-pain
Jump to: navigation, search
Name translation elongation factor activity
Categary Function
Go Slim No
Go Link GO:0003746
Unique Molecular Interactions 66
Total Molecular Interactions 71
Total Single Events 885
Pain Genes Associated 12

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for translation elongation factor activity. They are ordered first by their pain relevance and then by number of times they were reported for translation elongation factor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT227493 Binding of TCEA1 and SIRT2 1 0.01 1.55 1.93
2 INT224856 Binding of Bdnf and Eef2 1 0.14 0 1.02
3 INT43647 Binding of Eef1a1 and Man2a2 1 0.16 0.23 0.7
4 INT36511 Binding of Htr2a and Eef1a1 1 0.22 0 0.62
5 INT41250 Binding of Adra2a and Eef1a1 1 0.06 0.4 0.56
6 INT182813 EEF1A2 Negative_regulation of ITGAL 1 0.10 1.53 0.51
7 INT72525 Positive_regulation of TCEA1 Positive_regulation of Pomc 1 0.08 0 0.5
8 INT72524 Positive_regulation of TCEA1 Positive_regulation of Localization of Pomc 1 0.08 0 0.48
9 INT338086 PYCARD Positive_regulation of TCEA1 1 0.10 0 0.47
10 INT227495 Regulation of Binding of TCEA1 and SIRT2 1 0.01 0.45 0.45
11 INT56578 Eef1a1 Positive_regulation of Localization of Gnrh1 1 0.16 0 0.43
12 INT40208 Binding of Eef1a1 and Hils1 1 0.01 0.22 0.42
13 INT114516 Eef1a1 Positive_regulation of Transcription of co 1 0.00 0 0.41
14 INT207110 Adam3 Regulation of Gene_expression of Eef1a1 1 0.01 1 0.41
15 INT182817 EEF1A2 Positive_regulation of BMP2 1 0.26 1.62 0.28
16 INT239335 Eef1a2 Positive_regulation of Ppara 1 0.27 0.57 0.26
17 INT40964 Binding of Eef1a1 and Positive_regulation of Localization of Acot1 1 0.08 0 0.26
18 INT40854 Man2a2 Regulation of Regulation of Eef1a1 1 0.03 0 0.25
19 INT246576 EEF1A2 Negative_regulation of Negative_regulation of NOSTRIN 1 0.04 0.63 0.24
20 INT144588 Binding of EEF1A2 and pad 1 0.36 1.34 0.24
21 INT182816 EEF1A2 Negative_regulation of CRP 1 0.28 1.84 0.21
22 INT302731 Binding of Gfm1 and Hk 1 0.01 1 0.2
23 INT302732 Positive_regulation of Binding of Gfm1 and Hk 1 0.01 1 0.2
24 INT47842 Man2a2 Regulation of Eef1a1 1 0.01 0 0.18
25 INT230455 FOXG1 Negative_regulation of HBS1L 1 0.02 1.73 0.18
26 INT173499 EEF1A2 Negative_regulation of Cpox 1 0.07 0.39 0.14
27 INT173498 EEF1A2 Regulation of Cpox 1 0.04 0.39 0.14
28 INT317893 Binding of Eef1a1 and Mmp9 1 0.02 1.04 0.11
29 INT317888 Binding of Eef1a1 and Pik3r1 1 0.01 1.04 0.11
30 INT317898 Binding of Akt1 and Eef1a1 1 0.01 1.04 0.11
31 INT227137 Binding of HBS1L and BDNF-AS 1 0.00 1.32 0.08
32 INT212922 Binding of Car2 and Gfm1 1 0.02 0.19 0.06
33 INT239320 Eef1a2 Negative_regulation of Hmgcr 1 0.06 0.89 0.04
34 INT322671 Binding of Gfm1 and Pbrm1 1 0.00 0.96 0.04
35 INT206685 IMPA1 Positive_regulation of HBS1L 1 0.00 0.24 0.04
36 INT254908 ARSH Regulation of Eef1a1 1 0.00 0.89 0.04
37 INT351915 P2ry1 Regulation of Gfm1 1 0.01 0.86 0.03
38 INT351914 P2ry1 Regulation of Gene_expression of Gfm1 1 0.01 0.86 0.03
39 INT298872 RAB7A Regulation of Protein_catabolism of GFM1 1 0.47 0.22 0.03
40 INT317318 Binding of Gfm1 and Trap1 1 0.01 0.83 0
41 INT317317 Binding of Psmb10 and Gfm1 1 0.00 0.73 0
42 INT239325 Eef1a2 Negative_regulation of Lipc 1 0.11 0.84 0
43 INT217788 MIR181A1 Regulation of EIF5A 1 0.23 0.69 0
44 INT342731 Pink1 Regulation of Localization of Gfm1 1 0.00 0.61 0
45 INT311384 Binding of Cnbp and Eef2 1 0.07 0.15 0
46 INT338179 EEF1D Regulation of CDCP1 1 0.00 1.43 0
47 INT311393 Binding of Eef2 and Rps17 1 0.02 0.15 0
48 INT302596 Eef1a2 Negative_regulation of LDLR 1 0.14 0.31 0
49 INT182818 EEF1A2 Negative_regulation of STAR 1 0.01 1.48 0
50 INT221233 Positive_regulation of Binding of Gja3 and Gfm1 1 0.00 0 0
51 INT239350 Eef1a2 Positive_regulation of Apoa1 1 0.22 0.86 0
52 INT221239 Binding of Gja3 and Gfm1 1 0.00 0 0
53 INT260727 Binding of Gfm1 and NAFLD2 1 0.00 1.05 0
54 INT260726 Positive_regulation of Binding of Gfm1 and NAFLD2 1 0.00 1.05 0
55 INT311377 Binding of Eef2 and Pabpc1 1 0.01 0.15 0
56 INT317314 Gfm1 Positive_regulation of Gene_expression of Ros1 1 0.00 0.61 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for translation elongation factor activity. They are ordered first by their pain relevance and then by number of times they were reported in translation elongation factor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT48642 Positive_regulation of TCEA1 92 0.70 24.59 53.64
2 INT7531 Positive_regulation of Eef1a1 29 0.62 8.16 15.41
3 INT16659 Gene_expression of Eef1a1 34 0.64 6.1 11.85
4 INT6384 Regulation of Eef1a1 21 0.61 2.95 7.97
5 INT72523 Regulation of TCEA1 18 0.45 3.19 7.6
6 INT18578 Binding of Eef1a1 20 0.48 2.53 6.95
7 INT42132 Negative_regulation of TCEA1 13 0.51 4.12 6.28
8 INT42133 Gene_expression of TCEA1 17 0.60 5.61 5.55
9 INT18577 Negative_regulation of Eef1a1 20 0.39 3.57 5.24
10 INT52203 Negative_regulation of Positive_regulation of TCEA1 5 0.51 3.27 4.48
11 INT48643 Regulation of Positive_regulation of TCEA1 6 0.53 1.94 3.83
12 INT181249 Binding of TCEA1 8 0.32 2.12 3.66
13 INT139010 Regulation of Gfm1 16 0.32 5.02 3.27
14 INT137679 Localization of Gfm1 18 0.08 9.58 3.24
15 INT19393 Gene_expression of Gfm1 31 0.51 18.9 3.2
16 INT136784 Phosphorylation of Eef2 4 0.55 0 2.79
17 INT181250 Localization of TCEA1 6 0.75 1.54 2.61
18 INT75813 Positive_regulation of Positive_regulation of TCEA1 1 0.50 1.28 2.49
19 INT139008 Positive_regulation of Gfm1 21 0.35 7.79 2.34
20 INT71268 Positive_regulation of Gene_expression of Eef1a1 7 0.41 1.75 2.26
21 INT71266 Regulation of Gene_expression of Eef1a1 1 0.51 0 2.2
22 INT6628 Transcription of Eef1a1 4 0.16 2.59 1.8
23 INT136782 Positive_regulation of Phosphorylation of Eef2 1 0.41 0 1.78
24 INT32939 Positive_regulation of Positive_regulation of Eef1a1 2 0.19 0 1.67
25 INT136786 Regulation of Eef2 3 0.61 0 1.64
26 INT94827 Gene_expression of HBS1L 24 0.67 26.11 1.61
27 INT113785 Negative_regulation of Eef1a2 15 0.31 1.33 1.48
28 INT18493 Localization of Eef1a1 4 0.70 0.18 1.45
29 INT117148 Gene_expression of Eef1a1 6 0.07 2.32 1.42
30 INT15990 Binding of Gfm1 10 0.31 8.53 1.37
31 INT41893 Negative_regulation of HBS1L 16 0.23 8.98 1.19
32 INT158831 Phosphorylation of Gfm1 10 0.58 5.99 1.19
33 INT136787 Regulation of Regulation of Eef2 1 0.45 0 1.18
34 INT25451 Negative_regulation of Gfm1 13 0.27 8.22 1.06
35 INT158833 Regulation of Gene_expression of Gfm1 3 0.32 1.34 1.04
36 INT114830 Positive_regulation of Regulation of TCEA1 2 0.41 0.11 0.94
37 INT158832 Regulation of Phosphorylation of Gfm1 2 0.32 0.61 0.9
38 INT210762 Positive_regulation of Eef1a1 3 0.07 1.91 0.89
39 INT149641 Binding of Eef1a1 3 0.02 1.72 0.87
40 INT49846 Localization of HBS1L 4 0.24 1.31 0.86
41 INT147488 Gene_expression of Eef1a2 5 0.49 0.87 0.84
42 INT157293 Gene_expression of EEF1A2 4 0.78 4.07 0.77
43 INT46711 Negative_regulation of Binding of Eef1a1 1 0.28 0 0.76
44 INT37431 Binding of Eef1a2 1 0.17 0 0.75
45 INT40084 Binding of HBS1L 8 0.36 9.15 0.69
46 INT94826 Positive_regulation of HBS1L 13 0.40 4.62 0.61
47 INT71264 Negative_regulation of Gene_expression of Eef1a1 1 0.48 0 0.58
48 INT136781 Positive_regulation of Eef2 1 0.22 0 0.56
49 INT152525 Negative_regulation of Eef1a1 1 0.07 0.91 0.55
50 INT33574 Negative_regulation of Positive_regulation of Eef1a1 1 0.04 0.18 0.53
51 INT190571 Gene_expression of Eef2 9 0.35 1.64 0.43
52 INT297675 Negative_regulation of Positive_regulation of Eef1a1 1 0.01 0.92 0.4
53 INT30690 Localization of Eef1a2 2 0.42 0.94 0.39
54 INT147487 Negative_regulation of Gene_expression of Eef1a2 1 0.04 0.34 0.32
55 INT30689 Positive_regulation of Eef1a2 2 0.32 1.18 0.31
56 INT40347 Regulation of Regulation of Eef1a1 1 0.13 0.77 0.3
57 INT176895 Negative_regulation of EEF1A2 3 0.41 0.85 0.29
58 INT40963 Positive_regulation of Binding of Eef1a1 1 0.41 0 0.26
59 INT138921 Regulation of Gene_expression of Eef1a1 1 0.05 0.31 0.25
60 INT40346 Positive_regulation of Regulation of Eef1a1 1 0.14 0.7 0.24
61 INT117144 Negative_regulation of Gene_expression of Eef1a1 1 0.04 0.74 0.24
62 INT176898 Binding of EEF1A2 2 0.36 0.98 0.21
63 INT113786 Regulation of Eef1a2 2 0.33 1.34 0.2
64 INT260912 Positive_regulation of Gene_expression of Eef1a2 2 0.32 0.22 0.19
65 INT157295 Positive_regulation of Gene_expression of EEF1A2 1 0.70 1.57 0.19
66 INT317881 Transcription of Eef1a1 2 0.03 1.38 0.18
67 INT230456 Negative_regulation of Binding of HBS1L 1 0.05 1.73 0.18
68 INT292852 Positive_regulation of Binding of Gfm1 2 0.03 2.56 0.17
69 INT275338 Positive_regulation of Gene_expression of Gfm1 5 0.03 3.14 0.16
70 INT195213 Positive_regulation of Gene_expression of HBS1L 4 0.15 3.5 0.16
71 INT317276 Protein_catabolism of Gfm1 4 0.06 2.41 0.15
72 INT208863 Transcription of Eef2 1 0.24 0 0.14
73 INT164561 Negative_regulation of Negative_regulation of Eef1a2 1 0.01 0.06 0.1
74 INT157292 Positive_regulation of EEF1A2 1 0.70 0.8 0.09
75 INT266513 Localization of Eef1a1 1 0.11 0.82 0.08
76 INT157294 Regulation of EEF1A2 1 0.45 0.76 0.08
77 INT206703 Protein_catabolism of HBS1L 1 0.04 0 0.07
78 INT298902 Positive_regulation of Protein_catabolism of GFM1 1 0.49 0.44 0.06
79 INT292861 Regulation of Binding of Gfm1 1 0.03 0.06 0.06
80 INT93917 Transcription of TCEA1 1 0.13 0 0.05
81 INT275340 Positive_regulation of Localization of Gfm1 3 0.03 1.43 0.04
82 INT197172 Negative_regulation of Gene_expression of Gfm1 2 0.02 1.68 0.04
83 INT298907 Protein_catabolism of GFM1 1 0.86 0.22 0.03
84 INT206698 Regulation of HBS1L 4 0.09 3.06 0
85 INT206695 Gene_expression of GFM1 3 0.58 0.77 0
86 INT196399 Transcription of Gfm1 2 0.01 0.89 0
87 INT238458 Binding of GFM1 2 0.47 1.44 0
88 INT300037 Localization of EEF1A2 2 0.73 2.02 0
89 INT275337 Negative_regulation of Positive_regulation of Gfm1 2 0.02 0.76 0
90 INT93632 Negative_regulation of Gene_expression of TCEA1 1 0.14 0.09 0
91 INT352042 Negative_regulation of Gene_expression of HBS1L 1 0.13 0.76 0
92 INT322725 Positive_regulation of GFM1 1 0.15 1.19 0
93 INT348736 Gene_expression of Eef2 1 0.21 0 0
94 INT352039 Regulation of Gene_expression of HBS1L 1 0.13 0.94 0
95 INT217841 Regulation of EIF5A 1 0.53 0.74 0
96 INT227641 Phosphorylation of Eef2 1 0.80 0.22 0
97 INT217838 Positive_regulation of Regulation of EIF5A 1 0.59 0.74 0
98 INT275339 Regulation of Positive_regulation of Gfm1 1 0.02 0.3 0
99 INT217837 Gene_expression of EIF5A 1 0.51 1.08 0
100 INT217821 Positive_regulation of EIF5A 1 0.18 0.74 0
101 INT224980 Regulation of Eef1a1 1 0.01 0.24 0
102 INT275341 Regulation of Localization of Gfm1 1 0.02 0.3 0
103 INT192424 Negative_regulation of Localization of HBS1L 1 0.01 0.97 0
104 INT323187 Positive_regulation of Transcription of Gfm1 1 0.01 0.15 0
105 INT275336 Negative_regulation of Localization of Gfm1 1 0.02 0.3 0
106 INT298915 Binding of EEF1D 1 0.47 0.06 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox