GO:0003747

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Name translation release factor activity
Categary Function
Go Slim No
Go Link GO:0003747
Unique Molecular Interactions 14
Total Molecular Interactions 30
Total Single Events 154
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for translation release factor activity. They are ordered first by their pain relevance and then by number of times they were reported for translation release factor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT240730 Binding of CRYGD and MTRF1 4 0.03 4.18 1.39
2 INT225067 Binding of ETF1 and IGHG3 1 0.03 4.52 1.17
3 INT290551 Crh Positive_regulation of Etf1 1 0.01 0.38 0.73
4 INT290548 Positive_regulation of Crhr1 Positive_regulation of Etf1 1 0.01 0.38 0.72
5 INT225065 Binding of ETF1 and FANCB 1 0.01 2.07 0.59
6 INT225083 Binding of ETF1 and fc 1 0.00 2.13 0.57
7 INT288263 Binding of AFA and MTRF1 1 0.02 1.28 0.49
8 INT279410 Binding of MTRF1 and IGKV2-19 1 0.00 0.63 0.15
9 INT251529 MTRF1 Positive_regulation of CRYGD 1 0.00 0.31 0.12
10 INT279406 Binding of CRP and MTRF1 1 0.02 0.23 0.05
11 INT350737 Binding of CALM1 and ETF1 1 0.00 0 0.04
12 INT246150 MTRF1 Regulation of C2 1 0.00 0 0
13 INT198004 MCL1 Negative_regulation of C12orf65 1 0.01 1.12 0
14 INT323333 Binding of Ighm and Ict1 1 0.02 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for translation release factor activity. They are ordered first by their pain relevance and then by number of times they were reported in translation release factor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT19428 Gene_expression of MTRF1 42 0.08 27.17 10.43
2 INT177467 Negative_regulation of MTRF1 22 0.05 11.84 5.57
3 INT58102 Binding of MTRF1 4 0.08 6.39 3.05
4 INT67862 Negative_regulation of ETF1 3 0.29 1.45 1.91
5 INT194589 Regulation of MTRF1 2 0.03 3.27 1.44
6 INT177471 Localization of MTRF1 5 0.06 3.46 1.4
7 INT290531 Positive_regulation of Etf1 1 0.01 2.17 1.13
8 INT19431 Positive_regulation of Gene_expression of MTRF1 5 0.05 3.13 0.95
9 INT67863 Positive_regulation of Negative_regulation of ETF1 1 0.35 0.14 0.92
10 INT19429 Positive_regulation of MTRF1 3 0.08 1.62 0.75
11 INT19427 Regulation of Gene_expression of MTRF1 4 0.04 1.55 0.7
12 INT225072 Binding of ETF1 1 0.02 2.55 0.63
13 INT67860 Positive_regulation of ETF1 3 0.23 0.49 0.62
14 INT177468 Negative_regulation of Gene_expression of MTRF1 1 0.03 0.83 0.58
15 INT184815 Regulation of ETF1 3 0.40 1.83 0.54
16 INT67864 Positive_regulation of Positive_regulation of ETF1 2 0.23 0.07 0.5
17 INT67861 Negative_regulation of Positive_regulation of ETF1 1 0.22 0.07 0.46
18 INT349073 Localization of ETF1 1 0.11 0 0.44
19 INT199206 Negative_regulation of Ict1 9 0.05 3.67 0.21
20 INT225077 Positive_regulation of Binding of ETF1 1 0.03 0.82 0.21
21 INT220729 Positive_regulation of Gene_expression of ETF1 1 0.01 0.82 0.2
22 INT288274 Transcription of MTRF1 1 0.04 0.59 0.14
23 INT193178 Gene_expression of ETF1 2 0.09 0.56 0.1
24 INT199208 Gene_expression of Ict1 7 0.08 3.92 0.08
25 INT258464 Protein_catabolism of Ict1 1 0.11 0.48 0.06
26 INT199209 Regulation of Ict1 4 0.05 2.53 0.03
27 INT258461 Positive_regulation of Ict1 3 0.06 0.37 0
28 INT258462 Localization of Ict1 2 0.09 0.74 0
29 INT323331 Binding of Ict1 1 0.02 0 0
30 INT199207 Regulation of Gene_expression of Ict1 1 0.00 0.61 0
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