GO:0003777

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Name microtubule motor activity
Categary Function
Go Slim No
Go Link GO:0003777
Unique Molecular Interactions 57
Total Molecular Interactions 67
Total Single Events 611
Pain Genes Associated 10

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for microtubule motor activity. They are ordered first by their pain relevance and then by number of times they were reported for microtubule motor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT122660 Binding of CACNA1A and DNAH8 2 0.28 2.68 2.08
2 INT145473 Mastl Positive_regulation of Dnahc8 1 0.07 0.06 1.33
3 INT214411 DNAH8 Regulation of CAPN1 1 0.00 1.01 0.94
4 INT214408 ATP1A4 Regulation of DNAH8 1 0.04 1.01 0.94
5 INT145472 D2Mit212 Positive_regulation of Dnahc8 1 0.09 0.16 0.81
6 INT151552 NARG2 Regulation of DNAH8 1 0.00 0.64 0.5
7 INT151553 ERLEC1 Regulation of DNAH8 1 0.00 0.64 0.5
8 INT196634 IFNG Negative_regulation of DNAH8 1 0.03 1.49 0.47
9 INT145475 Negative_regulation of D2Mit212 Positive_regulation of Dnahc8 1 0.08 0.1 0.37
10 INT145474 D2Mit212 Regulation of Dnahc8 1 0.05 0.08 0.33
11 INT196623 Binding of KNG1 and Positive_regulation of DNAH8 1 0.01 0.19 0.32
12 INT196641 Binding of KNG1 and Negative_regulation of DNAH8 1 0.01 0.19 0.29
13 INT196621 PTGER2 Negative_regulation of Gene_expression of DNAH8 1 0.00 0.33 0.28
14 INT196626 Binding of DNAH8 and KNG1 1 0.00 0.08 0.27
15 INT196637 Binding of DNAH8 and SPANXB1 1 0.00 0.08 0.27
16 INT145616 Binding of Fez1 and Kif5a 1 0.05 0.25 0.27
17 INT145618 Binding of Fez1 and Kif27 1 0.13 0.25 0.27
18 INT145619 Binding of Fez1 and LOC691920 1 0.03 0.27 0.26
19 INT196615 TNF Positive_regulation of Negative_regulation of DNAH8 1 0.02 0.88 0.24
20 INT196622 IFNG Positive_regulation of Positive_regulation of DNAH8 1 0.03 0.87 0.24
21 INT196620 TNF Positive_regulation of Positive_regulation of DNAH8 1 0.03 0.88 0.24
22 INT196646 IFNG Positive_regulation of Negative_regulation of DNAH8 1 0.03 0.87 0.24
23 INT269330 DYNC1I2 Negative_regulation of PRKCA 1 0.03 0 0.15
24 INT269325 DYNC1I2 Positive_regulation of TMPO 1 0.01 0 0.15
25 INT272607 Binding of Dnahc8 and Nsf 1 0.02 0.42 0.14
26 INT43543 SH3RF3 Negative_regulation of DNAH8 1 0.03 0.27 0.14
27 INT342139 MUC7 Positive_regulation of Localization of DNAH8 1 0.00 0.06 0.13
28 INT196648 PTGER2 Regulation of DNAH8 1 0.00 0.14 0.12
29 INT198525 Binding of Kif5b and Ranbp2 1 0.23 0 0.1
30 INT54470 Binding of DNAH8 and ABCB1 1 0.30 0 0.1
31 INT125745 Nsf Negative_regulation of Dnahc8 1 0.06 0.33 0.1
32 INT54471 Positive_regulation of Binding of DNAH8 and ABCB1 1 0.29 0 0.1
33 INT196627 IL1B Regulation of DNAH8 1 0.00 0.63 0.09
34 INT196619 KNG1 Regulation of DNAH8 1 0.00 0.62 0.09
35 INT124036 Binding of App and Dnahc8 1 0.03 0.14 0.09
36 INT196642 IL1B Positive_regulation of Gene_expression of DNAH8 1 0.00 0 0.08
37 INT196640 PTGER2 Negative_regulation of DNAH8 1 0.00 0.46 0.08
38 INT272595 Binding of Dlg4 and Dnahc8 1 0.03 0.21 0.07
39 INT196628 IFNG Negative_regulation of Gene_expression of DNAH8 1 0.02 0.31 0.05
40 INT214015 Negative_regulation of Binding of Dnahc8 and Ank2 1 0.04 1.09 0.04
41 INT214013 Binding of Dnahc8 and Ank2 1 0.03 1.08 0.04
42 INT317070 DNAH8 Regulation of Localization of CA2 1 0.01 0.1 0.03
43 INT192678 PTEN Regulation of Dync1h1 1 0.02 0.5 0.03
44 INT218240 Binding of SAE1 and Dync1h1 1 0.00 0.17 0
45 INT200058 Binding of Ndn and Bbs4 1 0.30 0.29 0
46 INT340916 hop Regulation of Dnahc8 1 0.02 0.24 0
47 INT331118 Regulation of Binding of KIF22 and EBNA1BP2 1 0.04 0.16 0
48 INT200062 Binding of Ngfr and Bbs4 1 0.30 0.3 0
49 INT218040 Binding of DNAH8 and PRSS3 1 0.01 1.32 0
50 INT331115 Binding of KIF22 and EBNA1BP2 1 0.07 0.49 0
51 INT271026 Binding of Car2 and Dnahc8 1 0.00 0.44 0
52 INT329455 SLC7A7 Negative_regulation of DNAH8 1 0.00 0 0
53 INT211673 Tnni2 Negative_regulation of Dnahc8 1 0.06 0.52 0
54 INT218041 Positive_regulation of Binding of DNAH8 and PRSS3 1 0.01 1.37 0
55 INT211669 Tnni2 Negative_regulation of Dnahc8 1 0.01 0.57 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for microtubule motor activity. They are ordered first by their pain relevance and then by number of times they were reported in microtubule motor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT1558 Positive_regulation of Dnahc8 30 0.69 5.78 22.19
2 INT1561 Negative_regulation of Dnahc8 59 0.59 18.12 20.99
3 INT1756 Negative_regulation of DNAH8 105 0.59 42.73 20.24
4 INT1556 Regulation of Dnahc8 20 0.61 3.23 14.44
5 INT25585 Positive_regulation of DNAH8 39 0.70 17.96 7.85
6 INT26462 Gene_expression of DNAH8 44 0.78 19.36 7.31
7 INT21545 Regulation of DNAH8 22 0.59 8.67 6.48
8 INT33008 Gene_expression of Dync1h1 41 0.68 23.85 3.82
9 INT65642 Binding of Dync1h1 27 0.41 15.83 2.68
10 INT12485 Binding of DNAH8 17 0.48 4.24 2.54
11 INT1557 Binding of Dnahc8 6 0.48 1.5 2.51
12 INT74446 Positive_regulation of Dync1h1 25 0.59 13 2.38
13 INT106793 Positive_regulation of Positive_regulation of Dnahc8 3 0.50 0.58 1.8
14 INT30168 Gene_expression of Dnahc8 20 0.65 4.17 1.73
15 INT33431 Localization of Dnahc8 8 0.67 3.49 1.68
16 INT26464 Localization of DNAH8 15 0.80 4.3 1.33
17 INT1555 Positive_regulation of Regulation of Dnahc8 1 0.46 0 1.33
18 INT120698 Negative_regulation of Gene_expression of DNAH8 10 0.11 3.2 1.29
19 INT140394 Regulation of Dync1h1 7 0.39 2.59 1.25
20 INT22095 Negative_regulation of Dync1h1 11 0.48 5.17 1.08
21 INT88502 Positive_regulation of Negative_regulation of Dnahc8 2 0.48 0.61 1.04
22 INT50454 Regulation of Gene_expression of DNAH8 6 0.44 2.56 0.97
23 INT99155 Negative_regulation of Positive_regulation of DNAH8 3 0.42 0.6 0.93
24 INT73261 Negative_regulation of DYNC1I2 1 0.02 0.77 0.83
25 INT131875 Regulation of Regulation of Dnahc8 1 0.26 0.09 0.76
26 INT70537 Localization of DYNC1I2 2 0.23 0.21 0.66
27 INT48418 Localization of Dync1h1 4 0.61 1.54 0.44
28 INT196669 Phosphorylation of DNAH8 2 0.15 1.01 0.36
29 INT218235 Negative_regulation of Gene_expression of Dync1h1 2 0.37 0.57 0.34
30 INT346862 Regulation of Binding of Dync1h1 1 0.39 0.16 0.34
31 INT269391 Positive_regulation of Gene_expression of DYNC1I2 1 0.16 0 0.3
32 INT145611 Binding of LOC691920 1 0.02 0.27 0.26
33 INT214006 Negative_regulation of Gene_expression of Dnahc8 2 0.03 1.28 0.24
34 INT208856 Protein_catabolism of Dnahc8 1 0.06 0 0.23
35 INT170615 Phosphorylation of Dnahc8 1 0.22 0 0.23
36 INT208864 Regulation of Protein_catabolism of Dnahc8 1 0.03 0 0.23
37 INT43545 Positive_regulation of Negative_regulation of DNAH8 2 0.14 0.9 0.18
38 INT110166 Negative_regulation of Negative_regulation of DNAH8 1 0.36 0.36 0.18
39 INT26463 Regulation of Localization of DNAH8 1 0.45 0.41 0.18
40 INT269399 Gene_expression of DYNC1I2 1 0.21 0 0.15
41 INT76295 Gene_expression of KIF22 3 0.10 1.29 0.13
42 INT196691 Positive_regulation of Positive_regulation of DNAH8 2 0.10 1.23 0.13
43 INT269392 Phosphorylation of DYNC1I2 1 0.22 0.06 0.13
44 INT163225 Gene_expression of Bbs4 1 0.60 0.09 0.13
45 INT221195 Positive_regulation of Binding of Dnahc8 1 0.01 0.34 0.11
46 INT269374 Binding of DYNC1I2 2 0.10 0.23 0.1
47 INT341871 Positive_regulation of Binding of Dync1h1 1 0.37 0.61 0.1
48 INT320460 Regulation of Positive_regulation of DNAH8 1 0.01 2.04 0.08
49 INT269404 Regulation of Localization of DYNC1I2 1 0.12 0 0.08
50 INT91745 Positive_regulation of Gene_expression of DNAH8 1 0.45 0 0.06
51 INT264851 Regulation of Binding of DNAH8 1 0.10 0.45 0.04
52 INT264850 Positive_regulation of Binding of DNAH8 1 0.19 0.45 0.04
53 INT258075 Regulation of Negative_regulation of DNAH8 2 0.17 1.78 0
54 INT178835 Negative_regulation of Binding of Dync1h1 2 0.36 0.85 0
55 INT331138 Localization of KIF22 1 0.11 0.15 0
56 INT290261 Transcription of DYNC1I2 1 0.01 0.2 0
57 INT192674 Positive_regulation of Gene_expression of Dync1h1 1 0.32 1.67 0
58 INT158404 Phosphorylation of Dync1h1 1 0.15 0 0
59 INT331135 Binding of KIF22 1 0.07 0.18 0
60 INT331129 Protein_catabolism of KIF22 1 0.10 0 0
61 INT331948 Regulation of Gene_expression of Dnahc8 1 0.02 0.07 0
62 INT290238 Positive_regulation of DYNC1I2 1 0.00 0.29 0
63 INT331137 Regulation of Gene_expression of KIF22 1 0.07 0.29 0
64 INT76296 Positive_regulation of Gene_expression of KIF22 1 0.04 0 0
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