GO:0003779

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Name actin binding
Categary Function
Go Slim No
Go Link GO:0003779
Unique Molecular Interactions 1037
Total Molecular Interactions 1565
Total Single Events 12724
Pain Genes Associated 166

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for actin binding. They are ordered first by their pain relevance and then by number of times they were reported for actin binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT259233 Binding of Oprm1 and Flna 1 0.03 0.25 25.89
2 INT221180 Binding of OPRM1 and Flna 1 0.09 0.22 12.65
3 INT254001 Binding of Cxcr4 and Mif 1 0.52 14.17 7.18
4 INT259209 Binding of Glul and Flna 1 0.03 0 4.2
5 INT259230 Negative_regulation of Binding of Oprm1 and Flna 1 0.02 0 4.15
6 INT317511 Ppp1r9b Regulation of Oprm1 3 0.27 0.33 3.85
7 INT181455 Binding of Ccr5 and Ccl5 11 0.39 12.13 3.66
8 INT121651 Binding of CXCL12 and CXCR4 13 0.48 17.61 3.52
9 INT302118 Binding of Oprm1 and Ppp1r9b 2 0.24 0.26 3.45
10 INT166134 Binding of Cxcl12 and Cxcr4 3 0.49 5.69 3.17
11 INT182635 Binding of CCR5 and CCL5 2 0.09 4.19 3
12 INT259231 Binding of Oprm1 and Ppp1r9b 1 0.01 0 2.67
13 INT317528 Ppp1r9b Regulation of Grin1 1 0.18 0.2 2.48
14 INT317526 Binding of Hint1 and Gipc1 1 0.00 0.25 2.38
15 INT146930 CAP1 Regulation of ABCB1 1 0.29 0.3 2.19
16 INT351380 Ngf Regulation of TPM1 1 0.44 2.17 2.11
17 INT221181 Binding of GOPC and Flna 1 0.03 0.06 2.08
18 INT281381 FSCN1 Positive_regulation of Gene_expression of Gfap 1 0.06 1.13 1.98
19 INT134686 FSCN1 Positive_regulation of Gfap 1 0.00 0.71 1.89
20 INT151965 SORBS1 Positive_regulation of TRPV1 1 0.18 0 1.89
21 INT122964 FSCN1 Positive_regulation of Bdnf 1 0.01 1.14 1.79
22 INT282398 Binding of Mefv and Nlrp3 1 0.40 6.8 1.72
23 INT103592 CAP1 Negative_regulation of Gene_expression of CPOX 1 0.19 1.52 1.64
24 INT107965 Binding of HLA-B and Mefv 2 0.34 3.91 1.61
25 INT326509 Binding of ACE and VWF 1 0.05 2.07 1.59
26 INT168609 Binding of Itgb1 and Mmp9 1 0.02 0.41 1.58
27 INT12327 Igh-Dex Positive_regulation of Plec 1 0.03 0.73 1.57
28 INT221182 Negative_regulation of Binding of OPRM1 and Flna 1 0.07 0 1.57
29 INT45502 TNS1 Positive_regulation of VIP 1 0.47 0.52 1.5
30 INT150392 Binding of MEFV and PSTPIP1 2 0.51 10.49 1.44
31 INT259232 Binding of Flna and Positive_regulation of Localization of Oprm1 1 0.03 0 1.39
32 INT134679 FSCN1 Positive_regulation of MAPK8 1 0.01 0.56 1.39
33 INT259211 Binding of Ppp1r9b and Flna 1 0.06 0 1.33
34 INT281382 FSCN1 Positive_regulation of Sds 1 0.02 0.84 1.33
35 INT130786 Positive_regulation of Oprm1 Positive_regulation of Arc 1 0.27 0.9 1.31
36 INT64077 Trpv1 Positive_regulation of Kcnma1 1 0.00 0.37 1.27
37 INT305408 Binding of KCNMA1 and ST8SIA2 1 0.01 0.09 1.24
38 INT121190 KCNMA1 Positive_regulation of Gene_expression of IL6 1 0.03 0.54 1.24
39 INT21858 Maoa Regulation of Gene_expression of Spna1 1 0.12 0.18 1.24
40 INT162343 Positive_regulation of KCNMA1 Positive_regulation of ACE 1 0.06 1.25 1.23
41 INT259229 Positive_regulation of Binding of Oprm1 and Flna 1 0.02 0 1.23
42 INT162344 KCNMA1 Positive_regulation of ACE 1 0.06 1.25 1.23
43 INT21859 Maoa Regulation of Spna1 1 0.12 0.18 1.23
44 INT121189 KCNMA1 Positive_regulation of IL6 1 0.04 0.54 1.23
45 INT281383 FSCN1 Positive_regulation of Fig4 1 0.02 0.44 1.19
46 INT281379 Tcf21 Regulation of FSCN1 1 0.01 0.66 1.19
47 INT121191 KCNMA1 Positive_regulation of Phosphorylation of MAPK1 1 0.06 0.61 1.18
48 INT24796 ACE Positive_regulation of Localization of HMMR 1 0.00 0.58 1.16
49 INT125284 FSCN1 Positive_regulation of Positive_regulation of EPHB2 1 0.04 0.4 1.14
50 INT193288 CAP1 Positive_regulation of Pth 1 0.04 0.08 1.14
51 INT332776 FSCN1 Positive_regulation of Grin1 1 0.02 0.21 1.12
52 INT202968 Binding of MCRS1 and CAP1 1 0.03 2.46 1.08
53 INT81582 Plec Positive_regulation of st 1 0.02 0 1.07
54 INT81581 Plec Positive_regulation of Nudt14 1 0.01 0 1.07
55 INT181493 TRPV4 Regulation of Gene_expression of NGF 1 0.24 0.7 1.07
56 INT146496 Snta1 Positive_regulation of Gene_expression of Adrbk1 1 0.13 0.73 1.05
57 INT60047 Oprl1 Negative_regulation of Phosphorylation of Syn1 1 0.05 0.17 1.05
58 INT181450 Binding of Ccr5 and Ccl3 4 0.18 2.19 1.03
59 INT263232 Prkcg Positive_regulation of Trpv4 1 0.12 1.1 1.02
60 INT320021 Prkaca Regulation of Positive_regulation of Kcnma1 1 0.00 0.54 1
61 INT263227 Positive_regulation of Prkcg Regulation of Trpv4 1 0.07 0.95 1
62 INT106248 Binding of CCR5 and YY1 1 0.54 0.19 0.98
63 INT93306 Binding of TRPV1 and CAP1 2 0.18 0.07 0.97
64 INT128602 Binding of Kcnma1 and Gtf2ird2 1 0.00 0 0.97
65 INT275406 Binding of ITIH4 and Ccr5 1 0.09 2.88 0.97
66 INT275390 Binding of Ccr5 and Htatsf1 1 0.01 3.26 0.97
67 INT275409 Binding of ITIH4 and Cxcr4 1 0.09 2.87 0.97
68 INT275386 Binding of Cxcr4 and Htatsf1 1 0.01 3.25 0.97
69 INT93307 CAP1 Positive_regulation of TRPV1 1 0.15 0.07 0.96
70 INT281380 Fos Negative_regulation of Gene_expression of FSCN1 1 0.07 0.4 0.96
71 INT253836 Cck Regulation of DST 1 0.03 0.42 0.95
72 INT182190 Binding of IL8 and CXCR4 1 0.26 1.25 0.95
73 INT182210 Binding of CXCR4 and CXCL13 1 0.32 1.25 0.95
74 INT182205 Binding of CXCL5 and CXCR4 1 0.29 1.24 0.94
75 INT182195 Binding of CXCL1 and CXCR4 1 0.13 1.25 0.94
76 INT281377 FSCN1 Positive_regulation of Gene_expression of Fos 1 0.08 0.49 0.93
77 INT128652 ITIH4 Regulation of Gene_expression of CCR5 1 0.36 1.46 0.93
78 INT193291 Binding of CAP1 and Cfd 1 0.02 0.13 0.91
79 INT149386 Binding of Lyn and TRPV4 1 0.40 1.14 0.91
80 INT166135 Regulation of Binding of Cxcl12 and Cxcr4 1 0.30 0.9 0.91
81 INT63488 Sptan1 Positive_regulation of Rtcd1 1 0.03 0.34 0.91
82 INT113946 Binding of FLNA and OPRM1 1 0.10 0.37 0.9
83 INT52759 Oprd1 Regulation of Sptan1 1 0.03 0 0.9
84 INT112642 Positive_regulation of Kcnma1 Positive_regulation of Nav1 1 0.02 0 0.89
85 INT52761 Dll1 Regulation of Sptan1 1 0.07 0 0.89
86 INT326663 Bdnf Regulation of Positive_regulation of Arc 1 0.16 1.46 0.88
87 INT149559 Tgfb1 Positive_regulation of Gene_expression of Ccr5 1 0.00 0 0.88
88 INT149560 Tgfb1 Positive_regulation of Ccr5 1 0.00 0 0.88
89 INT254004 Cxcl12 Positive_regulation of Cxcr4 1 0.47 1.29 0.86
90 INT326664 Bdnf Positive_regulation of Arc 1 0.27 1.07 0.86
91 INT222243 Negative_regulation of Binding of Trpv1 and Ccr5 1 0.21 0.57 0.86
92 INT222244 Binding of Trpv1 and Ccr5 1 0.19 0.57 0.86
93 INT326661 Bdnf Positive_regulation of Gene_expression of Arc 1 0.27 1.96 0.86
94 INT146495 Snta1 Positive_regulation of Adrbk1 1 0.14 0.68 0.85
95 INT338695 CAP1 Regulation of Trpv1 1 0.01 0.14 0.85
96 INT167431 Binding of APP and MYO1C 1 0.23 1.38 0.83
97 INT189671 DAG1 Positive_regulation of PRKCA 3 0.12 0.71 0.82
98 INT19299 ANG Regulation of AVP 1 0.25 0 0.82
99 INT149558 Tgfb1 Positive_regulation of Gene_expression of Cxcr4 1 0.00 0 0.82
100 INT190868 Binding of Marcks and Ltp 1 0.01 0.87 0.81
101 INT54559 KCNMA1 Positive_regulation of Localization of TBXA2R 1 0.01 0.07 0.81
102 INT302119 Positive_regulation of Binding of Oprm1 and Ppp1r9b 1 0.02 0 0.77
103 INT190867 Binding of Marcks and Prkca 1 0.17 0.8 0.77
104 INT152945 Dlg4 Regulation of Cap1 1 0.11 0.18 0.76
105 INT159688 Trpv4 Negative_regulation of Trpv3 1 0.31 0.41 0.76
106 INT159689 Trpv4 Negative_regulation of Trpv1 1 0.36 0.41 0.76
107 INT152946 Homer1 Regulation of Cap1 1 0.32 0.18 0.76
108 INT159687 Trpv4 Negative_regulation of Trpv2 1 0.32 0.41 0.76
109 INT309735 Binding of CALM3 and TRPV4 1 0.14 0 0.75
110 INT127876 ACE Positive_regulation of Protein_catabolism of CALCA 1 0.28 0.63 0.75
111 INT322128 Binding of Ca2 and Trpv4 1 0.03 1.1 0.75
112 INT4915 Binding of Tac2 and Gipc1 1 0.01 0 0.74
113 INT182201 Binding of CXCR5 and CXCR4 1 0.36 1.15 0.72
114 INT182202 Binding of CXCR2 and CXCR4 1 0.31 1.15 0.72
115 INT123494 Binding of Egr1 and Ccr5 1 0.04 0.94 0.71
116 INT239538 Binding of CXCR4 and CALCRL 1 0.00 0.35 0.71
117 INT263236 DAG1 Positive_regulation of Prkcg 2 0.01 0.31 0.7
118 INT317832 Binding of Mefv and Il1 1 0.03 3.89 0.7
119 INT77689 Binding of Ace and Tenc1 1 0.28 0.65 0.7
120 INT338693 Aff3 Positive_regulation of Localization of CAP1 1 0.01 0.39 0.69
121 INT282664 Binding of Aif1 and Gfap 1 0.06 0 0.69
122 INT391 Binding of Agt and Ace 2 0.33 1.5 0.68
123 INT232617 Grid2ip Regulation of Cysltr1 1 0.03 0.58 0.68
124 INT170832 Cftr Regulation of Scnn1a 2 0.16 1.2 0.67
125 INT354249 Binding of Mtap6 and Ppp1r9b 1 0.24 0.07 0.67
126 INT254352 Binding of CXCR4 and Positive_regulation of Gene_expression of CXCL12 1 0.14 1.8 0.66
127 INT89875 Pdyn Positive_regulation of Localization of Myh6 1 0.09 0 0.66
128 INT281083 Binding of Gria1 and Gipc1 1 0.01 0 0.65
129 INT72146 POMC Positive_regulation of Phosphorylation of MYOT 1 0.00 0.25 0.65
130 INT207111 F2 Positive_regulation of Pawr 2 0.07 1.38 0.64
131 INT106247 Binding of CCR5 and CCL4 1 0.54 0.06 0.64
132 INT255994 Binding of Ang and Il1rn 1 0.09 1.21 0.63
133 INT121188 Negative_regulation of KCNMA1 Positive_regulation of IL6 1 0.04 0.3 0.63
134 INT239488 Spna1 Negative_regulation of Gene_expression of Timp1 1 0.00 0.94 0.62
135 INT335590 Camk4 Regulation of Ablim1 1 0.04 0.48 0.62
136 INT152766 TAT Positive_regulation of Positive_regulation of MYLK 1 0.44 0.67 0.61
137 INT21607 ACE Positive_regulation of ANGPT2 1 0.03 0.13 0.61
138 INT193290 CAP1 Regulation of Fth1 1 0.02 0 0.6
139 INT193265 CAP1 Regulation of STH 1 0.00 0 0.6
140 INT152765 TAT Regulation of Positive_regulation of MYLK 1 0.40 0.66 0.6
141 INT111184 Binding of GIPC1 and CHCHD8 1 0.00 0 0.59
142 INT56700 Penk Regulation of FER 1 0.00 0 0.59
143 INT193289 CAP1 Regulation of Pth 1 0.02 0 0.59
144 INT89012 DST Positive_regulation of Insr 1 0.01 0.86 0.59
145 INT202971 Binding of BAG3 and CAP1 1 0.04 1.26 0.59
146 INT202973 Binding of CAP1 and CPP 1 0.05 1.24 0.58
147 INT181619 ACE Positive_regulation of KNG1 1 0.33 0.97 0.58
148 INT202970 Binding of STC2 and CAP1 1 0.00 1.25 0.58
149 INT239489 Spna1 Negative_regulation of Timp1 1 0.00 0.89 0.57
150 INT73368 Ang1 Negative_regulation of Fabp6 1 0.00 0.44 0.56
151 INT281378 FSCN1 Positive_regulation of Gene_expression of Fig4 1 0.02 0.22 0.56
152 INT84603 Adrb1 Regulation of Gene_expression of Aqp2 1 0.00 0 0.56
153 INT77394 Binding of ARRB1 and GIPC1 1 0.01 0 0.56
154 INT244232 Binding of Ccr5 and Ccl4 3 0.17 1.48 0.55
155 INT544 Binding of ALB and GC 1 0.13 0 0.55
156 INT253835 Binding of DST and Fos 1 0.02 0 0.55
157 INT333991 Binding of FLNA and SELL 1 0.00 1.69 0.55
158 INT350169 Binding of DMD and MRI1 1 0.11 3.08 0.54
159 INT222691 Negative_regulation of Binding of FLNA and TNF 1 0.14 1.92 0.54
160 INT255999 Binding of Ang and H7 1 0.00 0.38 0.54
161 INT222692 Binding of FLNA and TNF 1 0.12 1.92 0.53
162 INT275388 Binding of Lamp1 and Cxcr4 1 0.01 1.45 0.52
163 INT232618 Gene_expression of Grid2ip Regulation of Localization of Gria1 1 0.28 0.86 0.52
164 INT275403 Binding of Cxcr4 and GOLPH3 1 0.00 1.45 0.52
165 INT292075 FSCN1 Positive_regulation of Gene_expression of Csnk1a1 1 0.03 0.57 0.52
166 INT275387 Binding of Lamp1 and Ccr5 1 0.01 1.45 0.52
167 INT241247 Binding of Pkd2 and Trpv4 1 0.54 1.22 0.52
168 INT275405 Binding of GOLPH3 and Ccr5 1 0.00 1.46 0.52
169 INT64514 Binding of TNNI3 and Mb 2 0.03 1.64 0.5
170 INT263228 Prkcg Regulation of Trpv4 1 0.07 0.36 0.5
171 INT352521 Cnn1 Positive_regulation of Cp 1 0.00 1.45 0.5
172 INT143922 TMSB4X Negative_regulation of Positive_regulation of Nfkb1 1 0.01 1.22 0.5
173 INT263235 Trpv4 Regulation of Trpv1 1 0.17 0.7 0.5
174 INT150391 Binding of MEFV and PYCARD 4 0.14 3 0.48
175 INT278379 Binding of Pstpip1 and Mefv 3 0.03 2.02 0.48
176 INT155958 Binding of Kcnk2 and Akap5 1 0.15 0.64 0.48
177 INT317834 Binding of Pstpip1 and Il1 1 0.00 2.03 0.48
178 INT232619 Binding of Gria1 and Grid2ip 1 0.23 0.51 0.48
179 INT195192 Akr1d1 Regulation of Msn 1 0.01 0.34 0.47
180 INT122832 AP1B1 Negative_regulation of Gene_expression of FLII 1 0.01 0 0.47
181 INT322131 Binding of Prkcg and Trpv4 1 0.04 0.75 0.46
182 INT207141 Tlr4 Positive_regulation of Positive_regulation of Pawr 1 0.05 0.79 0.46
183 INT37599 Ace Regulation of Localization of Insr 1 0.18 0 0.46
184 INT275407 Binding of ERVW-1 and Ccr5 1 0.00 1.74 0.46
185 INT19297 ANG Positive_regulation of AVP 1 0.28 0 0.46
186 INT342633 ACE Regulation of Gene_expression of AGT 1 0.01 0.14 0.46
187 INT275399 Binding of ERVW-1 and Cxcr4 1 0.00 1.73 0.46
188 INT17774 Alb Negative_regulation of Dnase1 1 0.02 0 0.46
189 INT150393 Binding of CASP1 and MEFV 2 0.16 2.48 0.45
190 INT335594 Myo5a Regulation of Hmmr 1 0.00 0.39 0.45
191 INT168129 Binding of Yy1 and Positive_regulation of Transcription of Tln2 1 0.02 0 0.44
192 INT178664 Binding of CCR5 and TH1L 1 0.04 1.04 0.44
193 INT281126 Binding of Ccr2 and Cxcr4 1 0.30 0.32 0.44
194 INT253996 Binding of Cxcr2 and Cxcr4 1 0.18 0.81 0.44
195 INT264295 Binding of DMD and IGF1 1 0.07 1.38 0.44
196 INT338692 CAP1 Negative_regulation of Positive_regulation of Aff3 1 0.01 0.2 0.44
197 INT168132 Binding of Yy1 and Tln2 1 0.01 0 0.43
198 INT261472 Binding of SPTBN1 and Gpi1 1 0.00 0.69 0.42
199 INT160046 INPPL1 Regulation of Gene_expression of PTEN 1 0.41 0.6 0.42
200 INT354206 Arc Positive_regulation of Accn2 1 0.02 0.57 0.42

Single Events

The table below shows the top 100 pain related interactions that have been reported for actin binding. They are ordered first by their pain relevance and then by number of times they were reported in actin binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT1724 Negative_regulation of ACE 437 0.59 315.64 74.48
2 INT61873 Gene_expression of Arc 128 0.78 128.25 52.24
3 INT221172 Binding of Flna 32 0.42 1.37 51.59
4 INT88322 Gene_expression of CCR5 111 0.78 77.36 39.84
5 INT129686 Gene_expression of FSCN1 46 0.15 18.91 34.47
6 INT109820 Gene_expression of Trpv4 121 0.78 39.69 33.11
7 INT88318 Gene_expression of CXCR4 208 0.77 189.67 31.72
8 INT1179 Negative_regulation of Ace 157 0.59 67.03 30.46
9 INT72252 Gene_expression of Kcnma1 63 0.64 20.47 29.56
10 INT10929 Positive_regulation of FLII 46 0.67 13.17 24.63
11 INT64076 Positive_regulation of Kcnma1 47 0.40 11.52 24.19
12 INT96741 Gene_expression of Cxcr4 62 0.78 32.3 22.14
13 INT112174 Gene_expression of Trpv4 47 0.78 26.26 20.09
14 INT104523 Positive_regulation of FSCN1 14 0.12 10.09 20.08
15 INT104527 Binding of FSCN1 18 0.23 14.75 19.6
16 INT9552 Positive_regulation of TNNI3 209 0.70 128.67 19.15
17 INT54294 Localization of Spnb4 9 0.78 0 18.64
18 INT167679 Gene_expression of Ccr5 74 0.75 59.03 18.16
19 INT27670 Negative_regulation of Ace 122 0.57 79.21 18.08
20 INT10555 Gene_expression of FLII 37 0.75 7.81 17.6
21 INT119233 Positive_regulation of Trpv4 65 0.70 20.21 17.3
22 INT20966 Positive_regulation of Arc 30 0.70 24.38 15.62
23 INT52591 Gene_expression of KCNMA1 78 0.76 13.95 15.55
24 INT16167 Negative_regulation of DMD 186 0.57 108.71 15.25
25 INT16166 Positive_regulation of DMD 348 0.67 133.22 15.06
26 INT89293 Positive_regulation of Gene_expression of CCR5 29 0.70 22.14 15
27 INT60044 Gene_expression of Syn1 38 0.78 4.98 14.61
28 INT20665 Gene_expression of ACE 87 0.78 51.71 14.19
29 INT60046 Positive_regulation of Syn1 16 0.70 2 13.9
30 INT12325 Gene_expression of Plec 47 0.72 11.92 13.35
31 INT121783 Positive_regulation of Gene_expression of Arc 30 0.70 29.22 13.02
32 INT104569 Gene_expression of Aqp2 23 0.60 16.56 12.23
33 INT21850 Gene_expression of Spna1 107 0.50 51.4 11.81
34 INT221167 Gene_expression of Flna 11 0.60 0.69 11.81
35 INT47702 Gene_expression of Sptan1 24 0.76 7.6 11.36
36 INT11479 Positive_regulation of KCNMA1 30 0.68 10.07 10.82
37 INT9550 Gene_expression of TNNI3 113 0.78 86.79 10.56
38 INT87393 Gene_expression of Ccr5 19 0.65 11 10.51
39 INT7458 Negative_regulation of Kcnma1 30 0.43 6.61 10.4
40 INT29740 Gene_expression of ANG 55 0.78 24.53 9.86
41 INT67101 Gene_expression of DST 47 0.54 25.92 9.59
42 INT68373 Negative_regulation of FLNA 59 0.57 60.46 9.55
43 INT149069 Positive_regulation of Cxcr4 24 0.68 12.21 9.54
44 INT56985 Gene_expression of MEFV 56 0.71 46.71 9.47
45 INT62254 Negative_regulation of FLII 20 0.48 4.11 9.44
46 INT21846 Localization of Spna1 27 0.78 5.14 9.22
47 INT20664 Binding of ACE 60 0.48 35.27 9.16
48 INT93309 Positive_regulation of CAP1 17 0.43 11.4 9.13
49 INT163054 Gene_expression of Msn 20 0.66 0.6 9.06
50 INT38173 Gene_expression of Ang 40 0.75 32.63 8.86
51 INT109724 Phosphorylation of FSCN1 5 0.07 3.15 8.82
52 INT89292 Positive_regulation of CCR5 27 0.70 15.12 8.59
53 INT93310 Gene_expression of CAP1 14 0.58 3.07 8.55
54 INT13085 Positive_regulation of ACE 50 0.70 44.2 8.31
55 INT221173 Negative_regulation of Binding of Flna 4 0.33 0.13 8.25
56 INT124702 Positive_regulation of Trpv4 21 0.69 7.14 8.2
57 INT389 Gene_expression of Ace 21 0.67 10.31 8.1
58 INT67374 Gene_expression of Mefv 15 0.74 49.1 8.07
59 INT25958 Regulation of Ace 26 0.59 11.88 7.87
60 INT189230 Gene_expression of GSN 12 0.75 25.04 7.6
61 INT84162 Negative_regulation of KCNMA1 26 0.58 5.05 7.58
62 INT1771 Positive_regulation of Ace 31 0.68 10.47 7.46
63 INT327801 Positive_regulation of Gene_expression of Aqp2 6 0.44 7.67 7.24
64 INT91758 Binding of CCR5 28 0.45 20.16 7.07
65 INT42038 Localization of ACE 26 0.80 8.88 7.06
66 INT153268 Positive_regulation of Ccr5 25 0.66 19 7.02
67 INT23782 Positive_regulation of Spna1 58 0.50 35.41 6.94
68 INT117186 Positive_regulation of CXCR4 29 0.69 24.19 6.84
69 INT38644 Positive_regulation of DST 30 0.53 12.48 6.59
70 INT163052 Regulation of Msn 11 0.38 1.21 6.31
71 INT142065 Phosphorylation of CFL1 8 0.78 0.87 6.3
72 INT124881 Binding of Trpv4 35 0.47 7.71 6.24
73 INT189177 Positive_regulation of Gene_expression of FSCN1 12 0.11 3.77 6.12
74 INT107315 Negative_regulation of CCR5 22 0.57 13.82 6.11
75 INT63728 Transcription of Syn1 6 0.72 0.38 6.07
76 INT149385 Positive_regulation of TRPV4 11 0.69 7.22 6.02
77 INT118440 Gene_expression of TRPV4 20 0.71 7.33 6.01
78 INT126481 Gene_expression of Cxcr4 69 0.77 34.99 6
79 INT63726 Positive_regulation of Transcription of Syn1 1 0.70 0.39 5.99
80 INT253974 Binding of Cxcr4 22 0.47 12.26 5.95
81 INT120089 Negative_regulation of Ccr5 7 0.58 10.36 5.91
82 INT254400 Negative_regulation of GSN 22 0.57 18.15 5.89
83 INT117189 Binding of CXCR4 34 0.37 24.27 5.81
84 INT103847 Positive_regulation of Ccr5 11 0.55 6.04 5.79
85 INT181406 Binding of Ccr5 16 0.45 17 5.78
86 INT96744 Positive_regulation of Gene_expression of Cxcr4 14 0.68 7.92 5.75
87 INT66549 Negative_regulation of Positive_regulation of FLII 9 0.36 3.08 5.74
88 INT129685 Negative_regulation of FSCN1 7 0.05 3.44 5.69
89 INT114993 Binding of Myo5a 15 0.30 11.46 5.48
90 INT81326 Positive_regulation of Gene_expression of Ang 17 0.67 18.5 5.46
91 INT13396 Gene_expression of DMD 125 0.75 57.81 5.45
92 INT16923 Positive_regulation of Tnni3 32 0.50 25.01 5.44
93 INT63957 Positive_regulation of Tnnt2 33 0.69 18.56 5.41
94 INT113112 Negative_regulation of CXCR4 39 0.58 28.28 5.36
95 INT95696 Gene_expression of Dmd 130 0.68 26.02 5.34
96 INT55634 Negative_regulation of Gene_expression of FLII 7 0.41 1.77 5.11
97 INT139162 Localization of Marcks 1 0.34 0 5.1
98 INT13051 Regulation of Kcnma1 12 0.12 2.09 5.06
99 INT21856 Regulation of Spna1 9 0.51 3.74 5.02
100 INT156296 Regulation of Trpv4 20 0.45 7.84 4.86
101 INT21854 Positive_regulation of Localization of Spna1 8 0.61 0.14 4.85
102 INT104342 Regulation of FSCN1 4 0.15 3.18 4.84
103 INT113948 Gene_expression of FLNA 32 0.73 36.06 4.81
104 INT87156 Phosphorylation of Marcks 8 0.40 2.48 4.8
105 INT94453 Gene_expression of ITGB1 50 0.75 18.41 4.72
106 INT139894 Negative_regulation of Msn 11 0.41 0.36 4.52
107 INT1901 Binding of Mefv 24 0.48 32.26 4.5
108 INT205272 Positive_regulation of Gene_expression of Plec 11 0.43 1.5 4.49
109 INT54297 Regulation of Localization of Spnb4 3 0.44 0 4.36
110 INT26477 Regulation of ACE 26 0.45 16.31 4.33
111 INT29327 Positive_regulation of Ace 13 0.67 8.79 4.33
112 INT208287 Binding of Msn 10 0.41 0.33 4.31
113 INT6967 Regulation of KCNMA1 28 0.61 3.37 4.3
114 INT35019 Phosphorylation of Syn1 11 0.82 0.33 4.28
115 INT39948 Binding of FLNA 45 0.42 58.05 4.27
116 INT167174 Negative_regulation of Gene_expression of FSCN1 6 0.06 3.05 4.25
117 INT387 Regulation of Ace 18 0.45 5.24 4.24
118 INT67138 Gene_expression of Gc 19 0.31 17.11 4.1
119 INT101301 Gene_expression of Aif1 17 0.42 16.43 4.06
120 INT221168 Localization of Flna 1 0.58 0.05 4.05
121 INT109821 Negative_regulation of Trpv4 19 0.55 6.86 3.98
122 INT63880 Positive_regulation of FLNA 29 0.59 13.88 3.97
123 INT50872 Positive_regulation of Tnni3 24 0.64 13.51 3.95
124 INT103843 Positive_regulation of Gene_expression of Ccr5 5 0.42 2.31 3.89
125 INT190858 Phosphorylation of Marcks 1 0.33 6.29 3.86
126 INT52755 Positive_regulation of Sptan1 6 0.67 1.57 3.82
127 INT1722 Protein_catabolism of ACE 10 0.88 2.61 3.76
128 INT142066 Positive_regulation of Phosphorylation of CFL1 5 0.48 0.24 3.73
129 INT195187 Positive_regulation of Msn 5 0.49 0.38 3.66
130 INT11761 Negative_regulation of DST 13 0.42 7.66 3.65
131 INT16165 Regulation of DMD 114 0.60 35.13 3.64
132 INT24711 Negative_regulation of Spna1 22 0.35 14.75 3.59
133 INT107555 Gene_expression of Marcks 8 0.58 1.22 3.56
134 INT193281 Binding of CAP1 7 0.07 4.57 3.53
135 INT102076 Regulation of DST 15 0.22 10 3.5
136 INT61875 Negative_regulation of Arc 4 0.34 5.61 3.49
137 INT545 Binding of GC 15 0.45 10.74 3.47
138 INT150395 Binding of MEFV 55 0.44 31.18 3.42
139 INT171998 Binding of DMD 58 0.47 38.13 3.35
140 INT84409 Binding of TNS1 6 0.48 2.96 3.33
141 INT11490 Binding of KCNMA1 13 0.37 3.61 3.32
142 INT63727 Positive_regulation of Gene_expression of Syn1 4 0.50 2.1 3.31
143 INT181496 Regulation of TRPV4 3 0.23 3.32 3.23
144 INT35017 Negative_regulation of Phosphorylation of Syn1 5 0.59 0.24 3.22
145 INT52756 Negative_regulation of Sptan1 7 0.42 1.31 3.19
146 INT160251 Gene_expression of Myo5a 48 0.63 37.14 3.16
147 INT112175 Negative_regulation of Gene_expression of Trpv4 8 0.59 3.7 3.12
148 INT96740 Transcription of Cxcr4 6 0.68 2.96 3.12
149 INT103674 Positive_regulation of Gene_expression of CXCR4 32 0.69 37.1 3.08
150 INT92355 Negative_regulation of Marcks 4 0.48 0 3.07
151 INT166879 Localization of Ccr5 4 0.71 3.62 2.97
152 INT221171 Positive_regulation of Localization of Flna 1 0.39 0.05 2.9
153 INT37734 Positive_regulation of Ang 18 0.46 9.17 2.87
154 INT168744 Negative_regulation of Regulation of Trpv4 1 0.42 3.26 2.87
155 INT17769 Positive_regulation of Dnase1 5 0.69 4.21 2.86
156 INT61311 Negative_regulation of Gene_expression of Syn1 4 0.59 0.48 2.85
157 INT48219 Gene_expression of SLC4A1 34 0.75 33.18 2.84
158 INT130784 Regulation of Gene_expression of Arc 4 0.54 4.9 2.84
159 INT248177 Localization of Cxcr4 17 0.79 4.87 2.82
160 INT56589 Positive_regulation of Localization of Spnb4 2 0.49 0 2.81
161 INT169402 Binding of Trpv4 8 0.47 5.13 2.78
162 INT21845 Regulation of Gene_expression of Spna1 5 0.22 0.9 2.78
163 INT50272 Positive_regulation of Cotl1 24 0.40 6.57 2.77
164 INT110233 Regulation of Gene_expression of CCR5 6 0.34 7.14 2.76
165 INT106433 Regulation of CCR5 11 0.59 6.93 2.75
166 INT8652 Protein_catabolism of Ace 10 0.94 4.7 2.74
167 INT1023 Negative_regulation of Pxk 13 0.59 0.76 2.7
168 INT211733 Phosphorylation of Gipc1 2 0.01 0 2.68
169 INT115852 Transcription of Trpv4 9 0.71 2.23 2.65
170 INT332774 Positive_regulation of Phosphorylation of FSCN1 1 0.02 0.69 2.63
171 INT111298 Gene_expression of ACTN4 12 0.70 9.42 2.6
172 INT11485 Localization of KCNMA1 7 0.09 1.81 2.6
173 INT87395 Binding of Ccr5 5 0.29 2.5 2.6
174 INT28817 Binding of TRPV4 6 0.39 3.92 2.59
175 INT99550 Regulation of FLNA 51 0.54 27.88 2.58
176 INT65081 Binding of TPM3 9 0.35 0.62 2.58
177 INT146931 Regulation of CAP1 1 0.44 0.22 2.58
178 INT91471 Positive_regulation of Gene_expression of Kcnma1 4 0.22 2.88 2.56
179 INT84599 Gene_expression of Aqp2 31 0.77 22.58 2.54
180 INT232510 Negative_regulation of Gene_expression of CXCR4 18 0.58 20.27 2.54
181 INT46646 Localization of FLNA 19 0.73 18.83 2.53
182 INT109822 Negative_regulation of Gene_expression of Trpv4 8 0.55 1.98 2.53
183 INT259224 Negative_regulation of Flna 1 0.23 0.15 2.51
184 INT115199 Localization of Trpv4 12 0.79 3.65 2.5
185 INT168097 Transcription of Tnnt2 1 0.07 2.12 2.47
186 INT190863 Negative_regulation of Phosphorylation of Marcks 1 0.23 4.71 2.47
187 INT159809 Localization of Trpv4 6 0.78 3.67 2.46
188 INT149068 Regulation of Cxcr4 3 0.44 3.77 2.46
189 INT54435 Binding of Sptan1 8 0.36 4.7 2.44
190 INT110231 Regulation of Gene_expression of Cxcr4 7 0.44 3.18 2.44
191 INT89146 Localization of Tnni3 7 0.51 4.31 2.38
192 INT81247 Gene_expression of Tnnt2 9 0.31 2.06 2.37
193 INT156301 Regulation of Trpv4 11 0.60 2.81 2.35
194 INT74695 Gene_expression of Ace 41 0.73 53.33 2.33
195 INT166490 Localization of Msn 9 0.80 0.61 2.32
196 INT55633 Positive_regulation of Gene_expression of FLII 5 0.42 1.54 2.32
197 INT156299 Phosphorylation of Trpv4 8 0.80 2.46 2.31
198 INT11487 Positive_regulation of Localization of KCNMA1 4 0.06 1.5 2.31
199 INT113775 Negative_regulation of Gene_expression of CCR5 6 0.43 3.97 2.28
200 INT181356 Positive_regulation of Gene_expression of Ccr5 11 0.66 8.3 2.24
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