GO:0003823

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Name antigen binding
Categary Function
Go Slim No
Go Link GO:0003823
Unique Molecular Interactions 300
Total Molecular Interactions 425
Total Single Events 3893
Pain Genes Associated 30

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for antigen binding. They are ordered first by their pain relevance and then by number of times they were reported for antigen binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT56458 Binding of GPM6A and IGHG3 4 0.02 0 3.31
2 INT154187 Il6 Positive_regulation of Gene_expression of Cd2 1 0.08 3.07 2.71
3 INT83425 Binding of CD40LG and IGHG3 11 0.21 4.56 2.09
4 INT85041 Binding of IGHG3 and MAX 1 0.00 0 2.09
5 INT122428 Binding of Ighm and Prkci 1 0.00 0 1.66
6 INT122430 Negative_regulation of Binding of Ighm and Prkci 1 0.00 0 1.36
7 INT83422 Binding of FANCB and IGHG3 3 0.12 5.09 1.22
8 INT285185 Binding of Ca2 and Cd2 1 0.25 0.24 1.21
9 INT108065 Negative_regulation of Binding of Ngf and IgG-2a 1 0.01 2.38 1.2
10 INT108064 Binding of Ngf and IgG-2a 1 0.01 2.36 1.19
11 INT62382 Binding of IGHG3 and SMPD2 1 0.02 0.37 1.17
12 INT225067 Binding of ETF1 and IGHG3 1 0.03 4.52 1.17
13 INT62379 Negative_regulation of Binding of IGHG3 and SMPD2 1 0.03 0.37 1.17
14 INT83427 Binding of IGHG3 and FRTS 3 0.03 1.92 1.12
15 INT62381 ADCY10 Positive_regulation of Localization of IGHG3 1 0.04 0.36 1.11
16 INT62380 ADCY10 Positive_regulation of IGHG3 1 0.03 0.36 1.11
17 INT109374 Ppp1cc Negative_regulation of Ppp2r1a 1 0.24 0 1.11
18 INT69340 Binding of Igh-6 and Ngf 2 0.06 1.04 1.06
19 INT353741 Binding of IGHE and Aia1 1 0.00 1.16 1.06
20 INT122429 Prkci Regulation of Gene_expression of Ighm 1 0.00 0 1.02
21 INT122431 Prkci Negative_regulation of Negative_regulation of Ighm 1 0.00 0 1.02
22 INT122433 Prkci Negative_regulation of Ighm 1 0.00 0 1.02
23 INT250016 Binding of IGHE and Il13 1 0.01 4.59 0.97
24 INT333499 Binding of IGHE and PHB2 1 0.14 4.08 0.95
25 INT126555 Binding of Ighg1 and Tnf 1 0.35 2.2 0.8
26 INT12396 Binding of Avp and IGKV1-5 3 0.04 1.38 0.75
27 INT82759 Binding of IGHG3 and OPRM1 2 0.06 0 0.7
28 INT284481 Binding of ABCA1 and Ighg1 1 0.00 1.39 0.7
29 INT211105 Binding of CRS and IGHE 1 0.02 3.63 0.66
30 INT33274 Binding of Oprd1 and Igh-6 1 0.12 0 0.66
31 INT62035 PDYN Regulation of Gene_expression of IGHE 1 0.33 0 0.57
32 INT141362 EP300 Negative_regulation of Transcription of IL2 1 0.17 0 0.56
33 INT122427 Ighm Positive_regulation of Positive_regulation of P9Ehs1 1 0.00 0 0.56
34 INT225082 Binding of IGHG3 and fc 6 0.01 3.6 0.55
35 INT169648 IGHG3 Regulation of AQP4 3 0.02 4.63 0.55
36 INT334500 Binding of IGHE and SPARCL1 1 0.01 1.47 0.55
37 INT167651 Binding of Oprd1 and Ep300 1 0.02 0.09 0.55
38 INT69343 Binding of NTRK1 and Igh-6 1 0.02 0.69 0.53
39 INT270984 Slc6a3 Regulation of IGKC 1 0.02 0 0.53
40 INT119030 Binding of POMC and Ighg1 1 0.06 0 0.52
41 INT130161 IgG-2a Positive_regulation of Gene_expression of Crhr1 1 0.01 0 0.52
42 INT130159 IgG-2a Regulation of Gene_expression of Crhr1 1 0.01 0 0.52
43 INT167652 Binding of Ep300 and Ngf 1 0.09 0.06 0.51
44 INT264330 Olr614 Negative_regulation of IgG-2a 1 0.00 1.07 0.51
45 INT167655 Binding of Polr2f and Ep300 1 0.01 0.06 0.51
46 INT122426 Binding of Hint1 and Ighm 1 0.00 0 0.5
47 INT161166 Binding of Aqp4 and Igh-6 1 0.03 2.58 0.49
48 INT264332 Olr614 Negative_regulation of Regulation of Igh-6 1 0.01 1.04 0.48
49 INT203150 Binding of Ighg2b and IgG2a 1 0.11 1.35 0.47
50 INT195552 Binding of Rela and Ep300 1 0.03 0.2 0.45
51 INT195554 Binding of Nfkb1 and Ep300 1 0.08 0.2 0.45
52 INT68252 Penk Positive_regulation of Transcription of Ighg1 1 0.44 0 0.44
53 INT87555 TPSAB1 Positive_regulation of IGHE 1 0.42 0.71 0.43
54 INT174507 Binding of HLA-B and LILRB4 1 0.02 1.16 0.43
55 INT83423 ADIPOQ Negative_regulation of Binding of IGHG3 1 0.02 0.31 0.42
56 INT304102 Il13 Positive_regulation of Gene_expression of IGHE 1 0.25 2.65 0.4
57 INT23664 Cd2 Negative_regulation of Fap 1 0.33 0 0.4
58 INT173977 Binding of TNF and Ighg1 1 0.03 0.28 0.39
59 INT23663 Cd2 Negative_regulation of Snx9 1 0.06 0 0.39
60 INT304099 Binding of IGHE and Il13 1 0.17 4.13 0.38
61 INT266553 Ppp2r1a Positive_regulation of Fig4 1 0.00 0 0.38
62 INT340850 Binding of IGHE and Baat 1 0.07 0.27 0.37
63 INT112020 Binding of Ighg1 and IgG2a 2 0.25 0.36 0.36
64 INT93202 Binding of IGHG3 and Oprm1 1 0.02 0 0.35
65 INT112455 Binding of IGHG3 and UGT2B7 1 0.07 0 0.35
66 INT93201 Positive_regulation of Binding of IGHG3 and OPRM1 1 0.02 0 0.35
67 INT310934 Positive_regulation of Tgm2 Positive_regulation of Binding of IGHE 1 0.14 1.33 0.34
68 INT300751 Binding of IGHE and Hand2 1 0.04 0 0.34
69 INT181451 Lck Regulation of Mbp 1 0.08 1.43 0.34
70 INT112024 Binding of Hand1 and Ighg1 2 0.30 0.84 0.33
71 INT112019 Binding of Ifng and Ighg1 1 0.10 0.3 0.33
72 INT241139 Ighg1 Positive_regulation of Hand2 1 0.06 0.65 0.32
73 INT241138 Ighg1 Positive_regulation of Hand1 1 0.06 0.64 0.32
74 INT284047 Vtcn1 Negative_regulation of Gene_expression of Ighg2b 1 0.05 0.68 0.3
75 INT107943 IgG-2a Positive_regulation of Adarb1 1 0.04 0 0.3
76 INT235958 Binding of Ighg1 and Aqp4 1 0.14 1.32 0.3
77 INT235977 Binding of AQP4 and Ighg1 1 0.03 1.31 0.3
78 INT187113 Binding of IGHG3 and MMP9 1 0.01 0.63 0.3
79 INT204089 Binding of KIR2DL3 and KIR2DS1 1 0.03 0.41 0.29
80 INT264331 Olr614 Regulation of IgG-2a 1 0.00 0.53 0.29
81 INT187107 Binding of IGHG3 and TIMP2 1 0.01 0.62 0.28
82 INT133391 Positive_regulation of Binding of IGHE and IgG 1 0.03 2.88 0.27
83 INT293900 TYRP1 Regulation of IGKC 1 0.01 0.11 0.27
84 INT133393 Binding of IGHE and IgG 1 0.03 2.86 0.27
85 INT267586 IL4 Positive_regulation of IGHE 1 0.00 1.42 0.27
86 INT264325 Olr614 Negative_regulation of Igh-6 1 0.01 0.54 0.26
87 INT351143 Binding of Cd3e and Ighg2a 1 0.00 1.56 0.25
88 INT287794 Binding of IGHG3 and AIP 1 0.05 2.8 0.24
89 INT256656 Binding of EP300 and HHIP 1 0.22 0 0.24
90 INT62033 POMC Regulation of Gene_expression of IGHE 1 0.64 0 0.24
91 INT235967 Binding of Ighm and Nqo1 1 0.00 1.45 0.23
92 INT335462 IGHE Regulation of Positive_regulation of PRKCA 1 0.07 0 0.23
93 INT202014 Binding of LILRA2 and MRAP 1 0.15 0.38 0.23
94 INT260870 Binding of HLA-E and IL7R 1 0.19 0.5 0.22
95 INT311872 IGHE Positive_regulation of Localization of Mmp9 1 0.01 1.35 0.22
96 INT146910 Cd2 Negative_regulation of Bp42 1 0.00 0 0.21
97 INT81159 Binding of PARP1 and IgG-2a 1 0.00 1.02 0.21
98 INT226368 Positive_regulation of TNF Positive_regulation of Positive_regulation of IGHE 1 0.11 0.92 0.2
99 INT325529 Binding of Stat3 and Ep300 1 0.01 0.22 0.19
100 INT211674 Gtf3a Regulation of Positive_regulation of Igj 1 0.01 0.8 0.19
101 INT325531 Positive_regulation of Binding of Stat3 and Ep300 1 0.02 0.22 0.19
102 INT285183 Cd2 Regulation of Ca2 1 0.30 0.23 0.18
103 INT250003 Binding of IGHE and IL13 1 0.03 1.16 0.18
104 INT237203 LGALS4 Regulation of Cd2 1 0.09 0 0.18
105 INT131162 Binding of CD58 and Cd2 1 0.01 1.21 0.18
106 INT237208 LGALS4 Regulation of Localization of Cd2 1 0.09 0 0.18
107 INT49058 Binding of IGHE and Positive_regulation of Localization of PTGDS 1 0.29 0.35 0.17
108 INT119267 Binding of EP300 and PPM1E 1 0.01 0.46 0.17
109 INT100456 Binding of Gm694 and Ighd 1 0.00 0.78 0.16
110 INT263901 Binding of Ighg1 and Slc3a2 1 0.00 0.89 0.16
111 INT226359 IL21 Negative_regulation of Gene_expression of IGHE 1 0.02 0.79 0.16
112 INT198307 IL10 Positive_regulation of Gene_expression of IGHG3 2 0.01 1.21 0.15
113 INT37659 IGHG3 Negative_regulation of F2 1 0.06 0.79 0.15
114 INT51355 Binding of FCGR1A and IGHE 1 0.36 0.1 0.15
115 INT293901 Positive_regulation of TYRP1 Regulation of IGKC 1 0.02 0.06 0.15
116 INT107647 Ighg1 Negative_regulation of Arigg4 1 0.01 0.5 0.14
117 INT272776 CD40 Positive_regulation of Gene_expression of IGHG3 1 0.01 0.18 0.14
118 INT107645 Arigg4 Negative_regulation of Ighg1 1 0.01 0.5 0.14
119 INT185454 IGHG1 Negative_regulation of Timp1 1 0.04 0.85 0.13
120 INT300731 IL10 Negative_regulation of Gene_expression of IGHE 1 0.03 0.23 0.13
121 INT185418 IGHG1 Negative_regulation of TIMP1 1 0.11 0.84 0.13
122 INT351144 Binding of Ighg2b and Ighg2a 1 0.00 0.78 0.12
123 INT220639 Binding of Apbb1 and Ighd 1 0.12 0.31 0.12
124 INT296029 Binding of HLA-DQA2 and LAG3 1 0.02 0.43 0.12
125 INT319731 Ep300 Positive_regulation of Binding of Rela 1 0.01 0.37 0.12
126 INT202543 Binding of IGHE and IL10 1 0.03 0.79 0.12
127 INT220633 Binding of Kat5 and Ighd 1 0.09 0.32 0.12
128 INT182481 Binding of Cav1 and Ighg2b 1 0.10 0 0.12
129 INT319727 Binding of Crebbp and Ep300 1 0.02 0.36 0.11
130 INT319728 Positive_regulation of Binding of Crebbp and Ep300 1 0.03 0.36 0.11
131 INT262207 Binding of Nr1i2 and Ep300 1 0.14 1.08 0.11
132 INT221066 Cd79a Regulation of Gene_expression of Ighm 1 0.01 0.93 0.1
133 INT173061 Binding of HIF1A and LILRA3 1 0.03 1.24 0.09
134 INT303759 IGHG3 Regulation of Localization of ROS1 1 0.07 0 0.09
135 INT270566 IGHE Regulation of IL4 1 0.21 0.99 0.09
136 INT16444 IGHG3 Negative_regulation of Binding of IL1A 1 0.11 0.42 0.09
137 INT35691 IGHG3 Positive_regulation of Gene_expression of SUPT7L 1 0.26 0.18 0.09
138 INT304581 IL4 Positive_regulation of Gene_expression of IGHE 1 0.17 0.35 0.09
139 INT194385 Il13 Positive_regulation of Gene_expression of IGHE 1 0.00 0.8 0.09
140 INT131163 Negative_regulation of Binding of CD58 and Cd2 1 0.01 0.6 0.09
141 INT185073 Bpifa2 Positive_regulation of Ighg1 1 0.27 0.93 0.09
142 INT270567 IGHE Regulation of IL13RA2 1 0.23 0.99 0.09
143 INT270569 IGHE Regulation of IL5 1 0.18 1.04 0.09
144 INT202541 IL4 Regulation of IGHE 1 0.02 0.49 0.08
145 INT36712 Cd2 Regulation of Localization of Avp 1 0.44 0 0.08
146 INT36713 Cd2 Positive_regulation of Avp 1 0.26 0 0.08
147 INT287880 Binding of CREB1 and EP300 1 0.01 0 0.08
148 INT202545 Binding of IGHE and IL4 1 0.03 0.49 0.08
149 INT37660 IGHG3 Negative_regulation of ANGPTL5 1 0.01 0.45 0.08
150 INT296034 FOXP3 Negative_regulation of Gene_expression of IL7R 1 0.10 0.63 0.08
151 INT279767 Binding of IGHG3 and KRT19 1 0.01 0.84 0.07
152 INT351142 Binding of Cd3e and Ighg2b 1 0.03 0.6 0.07
153 INT225068 Binding of FCAR and IGHG3 1 0.02 0.27 0.07
154 INT319001 Binding of IGHG3 and ACCS 1 0.00 1.76 0.07
155 INT187104 Binding of IGHG3 and TIMP1 1 0.01 0.22 0.07
156 INT230883 Binding of IGHE and tryptase 1 0.01 0.23 0.07
157 INT119266 CDKN1A Regulation of EP300 1 0.47 0.44 0.07
158 INT225064 Binding of IGHA1 and IGHG3 1 0.01 1.54 0.07
159 INT74033 Binding of IGHG3 and Ighg1 2 0.08 0.87 0.06
160 INT332017 Binding of Ighm and Mbl1 1 0.11 0.26 0.06
161 INT320160 Binding of FCER2 and IGHG3 1 0.00 0.35 0.06
162 INT237191 Cd2 Positive_regulation of LPT 1 0.00 0.15 0.06
163 INT329839 Negative_regulation of Tnfsf13b Negative_regulation of Gene_expression of Ighm 1 0.05 2.28 0.06
164 INT320161 Binding of IGHE and IGHG3 1 0.02 0.35 0.06
165 INT262173 Binding of Msx2 and Ep300 1 0.07 0.55 0.06
166 INT197553 Binding of NFE2L2 and LILRA3 1 0.03 0.43 0.06
167 INT202542 IGHE Positive_regulation of Localization of IL4 1 0.06 0.44 0.05
168 INT275126 Binding of CSTB and IGHG3 1 0.00 0.49 0.05
169 INT115324 Binding of FCGR3A and Ighm 1 0.00 0.56 0.05
170 INT347021 Cd86 Positive_regulation of Gene_expression of IGHE 1 0.03 0.18 0.05
171 INT220851 Binding of Cd48 and Cd244 1 0.04 0.55 0.05
172 INT303247 Binding of LILRA3 and Trim3 1 0.01 0.13 0.05
173 INT202547 IGHE Positive_regulation of Localization of IL13 1 0.04 0.44 0.05
174 INT320353 IFNA1 Positive_regulation of Gene_expression of Ighg2b 1 0.02 0 0.05
175 INT323755 IGHG3 Negative_regulation of ACE2 1 0.01 1.09 0.05
176 INT328668 Binding of CSF2 and IGHG3 1 0.03 0.59 0.05
177 INT303249 Binding of LILRA3 and Dlgap1 1 0.01 0.13 0.05
178 INT115323 Binding of GPI and Ighm 1 0.00 0.56 0.05
179 INT173052 Binding of LILRA3 and VHLL 1 0.01 0.62 0.05
180 INT16442 Binding of IGHG3 and IL1A 1 0.10 0.36 0.05
181 INT279763 Binding of IGHG3 and KRT18 1 0.00 0.43 0.04
182 INT235969 Binding of Ighg1 and Nqo1 1 0.01 2.63 0.04
183 INT315945 IgG Positive_regulation of Gene_expression of Ighm 1 0.13 0.56 0.04
184 INT202546 Binding of FCER1A and IGHE 1 0.02 0.49 0.04
185 INT279764 Binding of IGHG3 and BTG3 1 0.00 0.3 0.04
186 INT279766 Binding of IGHG3 and TGM1 1 0.01 0.3 0.04
187 INT334497 Positive_regulation of IGHG3 Positive_regulation of IGHE 1 0.01 0.81 0.04
188 INT290163 Atp6v1e1 Positive_regulation of Ighm 1 0.12 0.26 0.04
189 INT334496 IGHG3 Positive_regulation of IGHE 1 0.01 0.75 0.04
190 INT279765 Binding of IGHG3 and KRT8 1 0.01 0.42 0.04
191 INT195195 IL4 Regulation of Gene_expression of IGHE 1 0.10 0.68 0.04
192 INT225569 Binding of Ncoa6 and Ep300 1 0.18 0.63 0.04
193 INT315943 Ighm Positive_regulation of Gene_expression of IgG 1 0.13 0.56 0.04
194 INT268909 Binding of TRGV9 and IGKV1-5 1 0.18 0.06 0.04
195 INT341237 ROS1 Negative_regulation of Ppp2r1a 1 0.01 0.31 0.04
196 INT270586 Binding of IGHE and IgG-2a 1 0.16 0.75 0.03
197 INT303248 LILRA3 Positive_regulation of Protein_catabolism of Psd 1 0.01 0.2 0.03
198 INT259935 CSK Positive_regulation of Negative_regulation of LCK 1 0.09 0.57 0.03
199 INT235544 Binding of Ighm and Olr1 1 0.00 0.68 0.03
200 INT315437 Binding of IGHG3 and SEMA4B 1 0.19 0.12 0.03

Single Events

The table below shows the top 100 pain related interactions that have been reported for antigen binding. They are ordered first by their pain relevance and then by number of times they were reported in antigen binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT3375 Gene_expression of IGHE 535 0.77 387.47 65.46
2 INT4004 Gene_expression of IGHG3 321 0.71 221.03 42.33
3 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16
4 INT8775 Binding of IGHE 167 0.48 102.61 23.54
5 INT9220 Gene_expression of Ighg1 125 0.77 85.74 15.92
6 INT3796 Gene_expression of Ighm 130 0.77 69.61 13.78
7 INT1125 Positive_regulation of IGHG3 130 0.69 112.07 13.18
8 INT1139 Gene_expression of IgG-2a 35 0.65 19.19 12
9 INT14867 Gene_expression of Igh-6 47 0.67 30.05 11.75
10 INT11794 Gene_expression of Cd2 27 0.76 17.31 10.99
11 INT701 Localization of IGHE 87 0.80 40.5 10.62
12 INT16449 Binding of IGHG3 67 0.48 39.55 10.59
13 INT35164 Negative_regulation of IGHE 96 0.58 76.3 9.74
14 INT3988 Positive_regulation of Gene_expression of IGHE 98 0.68 91.46 9.61
15 INT152668 Negative_regulation of EP300 13 0.38 7.78 9.03
16 INT1138 Positive_regulation of IgG-2a 16 0.68 5.59 8.11
17 INT2971 Regulation of IGHE 42 0.61 28.81 7.87
18 INT1127 Negative_regulation of IGHG3 32 0.28 21.1 7.37
19 INT3795 Positive_regulation of Ighm 46 0.68 22.43 6.47
20 INT57720 Localization of IGHG3 33 0.74 20.24 6.25
21 INT12818 Regulation of IgG-2a 9 0.37 3.23 6.07
22 INT14849 Binding of IgG-2a 12 0.39 5.96 6.06
23 INT26962 Negative_regulation of IgG-2a 12 0.42 6.07 5.31
24 INT62041 Negative_regulation of Gene_expression of IGHE 37 0.58 37.86 5.27
25 INT174193 Gene_expression of LILRA3 20 0.28 12.65 5.1
26 INT68244 Positive_regulation of Ighg1 60 0.61 48.86 5.01
27 INT19188 Binding of Igh-6 11 0.48 2.97 4.88
28 INT2213 Regulation of EP300 10 0.54 4.72 4.5
29 INT14026 Positive_regulation of Igh-6 24 0.68 10.84 4.32
30 INT41878 Positive_regulation of EP300 13 0.61 5.24 3.95
31 INT9223 Localization of Ighg1 22 0.78 11.03 3.67
32 INT36799 Negative_regulation of Ighm 21 0.41 17.47 3.65
33 INT62386 Negative_regulation of Gene_expression of IGHG3 12 0.20 7.94 3.62
34 INT22270 Regulation of IGKV1-5 13 0.39 3.56 3.54
35 INT9999 Regulation of Gene_expression of IGHE 32 0.60 15.75 3.53
36 INT14201 Localization of Igh-6 9 0.81 3.29 3.36
37 INT52021 Regulation of IGHG3 34 0.39 22.43 3.3
38 INT4003 Positive_regulation of Gene_expression of IGHG3 31 0.46 20.38 3.16
39 INT23577 Localization of IgG-2a 8 0.73 5.32 3.1
40 INT24795 Regulation of Igh-6 7 0.51 3.08 2.93
41 INT17417 Positive_regulation of Ighd 16 0.69 24.29 2.8
42 INT161310 Negative_regulation of LCK 17 0.42 8.75 2.74
43 INT10510 Negative_regulation of Igh-6 13 0.45 10.37 2.68
44 INT24871 Negative_regulation of Binding of IGHE 10 0.58 2.87 2.64
45 INT19430 Positive_regulation of IGHA1 10 0.67 6.42 2.58
46 INT28815 Gene_expression of Ighd 18 0.65 11.02 2.48
47 INT49930 Binding of Ighg1 21 0.37 13.27 2.43
48 INT91837 Negative_regulation of Ppp2r1a 4 0.48 0.95 2.41
49 INT15127 Regulation of Cd2 4 0.44 1.06 2.38
50 INT173504 Positive_regulation of Gene_expression of Ighg1 16 0.47 7.2 2.36
51 INT171511 Gene_expression of EP300 14 0.53 4.17 2.29
52 INT35027 Positive_regulation of Gene_expression of Igh-6 6 0.02 4.26 2.24
53 INT35866 Transcription of IGHE 9 0.60 12.83 2.19
54 INT122671 Positive_regulation of LCK 4 0.13 2.69 2.14
55 INT26123 Regulation of Ep300 6 0.23 1.22 2.03
56 INT3797 Positive_regulation of Gene_expression of Ighm 16 0.47 9.4 2.01
57 INT171514 Binding of EP300 13 0.32 4.32 2.01
58 INT54234 Binding of Cd2 6 0.35 2.14 1.99
59 INT186134 Binding of IGHA1 5 0.01 4.71 1.99
60 INT22269 Gene_expression of IGKV1-5 32 0.50 1.71 1.95
61 INT26124 Negative_regulation of Ep300 5 0.37 1.25 1.94
62 INT184006 Gene_expression of Ighg2b 21 0.71 7.97 1.86
63 INT21999 Regulation of Gene_expression of IGHG3 8 0.30 3.26 1.84
64 INT9996 Positive_regulation of Localization of IGHE 8 0.49 1.95 1.8
65 INT20207 Binding of Ighm 14 0.46 2.88 1.79
66 INT172622 Localization of EP300 8 0.65 2.56 1.72
67 INT56100 Negative_regulation of Gene_expression of Ighm 5 0.48 2.07 1.72
68 INT4217 Negative_regulation of Negative_regulation of IGHG3 3 0.11 0.69 1.7
69 INT22058 Positive_regulation of Igha 7 0.49 5.29 1.69
70 INT6904 Negative_regulation of Cd2 5 0.42 1.37 1.64
71 INT68250 Regulation of Gene_expression of Ighg1 7 0.40 2.99 1.56
72 INT107641 Negative_regulation of Ighg1 19 0.39 11.44 1.54
73 INT204105 Positive_regulation of KIR2DL3 4 0.49 2.18 1.44
74 INT122672 Regulation of Positive_regulation of LCK 1 0.06 1.15 1.44
75 INT112013 Negative_regulation of Gene_expression of Ighg1 7 0.38 3.57 1.42
76 INT105938 Negative_regulation of Gene_expression of Igh-6 7 0.30 4.7 1.36
77 INT11984 Gene_expression of IGHA1 9 0.54 6.12 1.35
78 INT56143 Regulation of Gene_expression of Igh-6 2 0.20 2.03 1.32
79 INT211645 Gene_expression of Igj 1 0.64 7.1 1.31
80 INT181961 Gene_expression of IL7R 10 0.75 3.9 1.29
81 INT12148 Positive_regulation of IGKV1-5 24 0.57 3.13 1.25
82 INT68248 Transcription of Ighg1 3 0.61 3.02 1.25
83 INT15128 Positive_regulation of Cd2 3 0.64 1.45 1.25
84 INT70821 Positive_regulation of Ep300 4 0.25 1.47 1.2
85 INT233406 Localization of Cd2 4 0.44 0.13 1.2
86 INT12150 Negative_regulation of IGKV1-5 24 0.55 1.91 1.17
87 INT27776 Positive_regulation of Gene_expression of IgG-2a 2 0.05 3.48 1.14
88 INT3512 Gene_expression of Igha 9 0.60 7.71 1.13
89 INT139679 Positive_regulation of Ighg2b 11 0.55 10.57 1.1
90 INT60516 Regulation of Binding of IgG-2a 1 0.50 0.07 1.09
91 INT56915 Positive_regulation of Positive_regulation of IgG-2a 1 0.09 0.13 1.09
92 INT131116 Localization of IGKV1-5 10 0.36 2.13 1.06
93 INT35865 Positive_regulation of Transcription of IGHE 3 0.44 2.61 1.03
94 INT125422 Protein_catabolism of IGKV1-5 2 0.85 0.27 1.03
95 INT24868 Localization of Ighd 7 0.78 2.08 1.01
96 INT9081 Positive_regulation of Positive_regulation of IGHE 5 0.42 7.13 1
97 INT167650 Binding of Ep300 1 0.09 0.14 1
98 INT248588 Gene_expression of LCK 9 0.28 4.9 0.98
99 INT183466 Positive_regulation of Localization of IGHG3 1 0.03 1.55 0.97
100 INT22004 Positive_regulation of Binding of IGHE 7 0.49 3.29 0.96
101 INT171113 Binding of Ighg2b 3 0.47 2.85 0.96
102 INT122197 Regulation of Localization of IGHE 3 0.42 0.92 0.95
103 INT138683 Regulation of Ighg1 15 0.30 7.95 0.94
104 INT122422 Negative_regulation of Phosphorylation of Ighm 1 0.01 0 0.91
105 INT15129 Positive_regulation of Gene_expression of Cd2 3 0.49 0.95 0.89
106 INT57059 Negative_regulation of IGKC 4 0.24 1.34 0.86
107 INT192404 Localization of Ighm 15 0.48 5.8 0.85
108 INT19186 Negative_regulation of Gene_expression of IgG-2a 1 0.04 0.27 0.85
109 INT122425 Phosphorylation of Ighm 1 0.01 0 0.85
110 INT187074 Negative_regulation of Gene_expression of LILRA3 3 0.14 1.09 0.84
111 INT161311 Positive_regulation of Negative_regulation of LCK 2 0.45 0.74 0.83
112 INT146942 Gene_expression of Lck 1 0.46 1.3 0.83
113 INT11983 Regulation of IGHA1 3 0.12 1.88 0.82
114 INT254253 Transcription of Ighm 5 0.45 3.6 0.81
115 INT74097 Gene_expression of Ep300 6 0.52 1.89 0.73
116 INT14202 Regulation of Localization of Igh-6 1 0.62 0 0.73
117 INT122670 Negative_regulation of Positive_regulation of LCK 1 0.06 0.58 0.72
118 INT174518 Positive_regulation of Gene_expression of KIR2DL3 3 0.49 1.05 0.7
119 INT119638 Gene_expression of KIR2DL3 6 0.75 1.35 0.69
120 INT14203 Negative_regulation of Localization of Igh-6 1 0.43 0 0.69
121 INT249114 Gene_expression of Cd48 2 0.10 5.06 0.68
122 INT102655 Positive_regulation of Positive_regulation of Ighm 2 0.32 0.74 0.67
123 INT87931 Binding of IGKV1-5 13 0.06 2.03 0.65
124 INT61816 Negative_regulation of Binding of IGHG3 4 0.28 0.92 0.63
125 INT329708 Transcription of LCK 1 0.04 1.54 0.63
126 INT11437 Positive_regulation of IGKC 3 0.20 0.5 0.59
127 INT187075 Negative_regulation of LILRA3 2 0.14 1.82 0.57
128 INT334504 Regulation of Transcription of IGHE 1 0.29 7.97 0.57
129 INT220110 Negative_regulation of Gene_expression of Ighd 1 0.13 2.55 0.57
130 INT3513 Negative_regulation of Igha 9 0.38 7.43 0.56
131 INT125821 Regulation of Positive_regulation of IGHE 6 0.40 5.38 0.53
132 INT184049 Positive_regulation of Gene_expression of Ighg2b 2 0.40 1.54 0.53
133 INT4642 Regulation of Regulation of IGHE 1 0.45 1.88 0.53
134 INT203131 Regulation of Binding of Ighg2b 1 0.31 1.36 0.49
135 INT211655 Positive_regulation of Gene_expression of Igj 1 0.57 3.79 0.49
136 INT106157 Positive_regulation of Positive_regulation of Igh-6 1 0.50 0.18 0.48
137 INT187070 Positive_regulation of Negative_regulation of LILRA3 1 0.16 0.51 0.45
138 INT233407 Regulation of Localization of Cd2 1 0.04 0.13 0.44
139 INT68237 Positive_regulation of Transcription of Ighg1 1 0.44 0 0.43
140 INT48405 Regulation of Gene_expression of Cd2 1 0.21 0.6 0.43
141 INT28912 Positive_regulation of Cd2 3 0.50 0.48 0.41
142 INT39350 Positive_regulation of Ighg2a 2 0.35 2.39 0.37
143 INT220962 Positive_regulation of Localization of Ighg1 2 0.46 2.58 0.37
144 INT95906 Negative_regulation of Positive_regulation of IGHE 6 0.55 1.56 0.36
145 INT312831 Negative_regulation of Lck 3 0.13 2.46 0.36
146 INT243978 Binding of Ppp2r1a 2 0.08 0 0.36
147 INT54101 Phosphorylation of IGHG3 1 0.13 1.09 0.36
148 INT329707 Negative_regulation of Transcription of LCK 1 0.04 0.9 0.35
149 INT204115 Positive_regulation of Positive_regulation of KIR2DL3 1 0.49 0.53 0.35
150 INT260878 Binding of IL7R 1 0.33 0.87 0.35
151 INT187587 Binding of Ep300 11 0.35 2.37 0.34
152 INT235306 Gene_expression of IGKC 5 0.38 3.18 0.34
153 INT224714 Localization of Ighg2b 4 0.73 0.48 0.33
154 INT181413 Regulation of Lck 2 0.36 2.54 0.33
155 INT220954 Positive_regulation of Localization of IgG-2a 1 0.49 1.6 0.33
156 INT58833 Negative_regulation of Gene_expression of Cd2 1 0.11 1.1 0.32
157 INT4218 Transcription of IGHG3 7 0.63 2.76 0.31
158 INT100455 Binding of Ighd 1 0.37 1.61 0.31
159 INT323835 Negative_regulation of Binding of Ighg1 1 0.23 0.67 0.31
160 INT323834 Regulation of Binding of Ighg1 1 0.24 0.69 0.31
161 INT74136 Localization of IGHA1 1 0.63 0.54 0.3
162 INT192406 Regulation of Ighm 16 0.31 5.58 0.29
163 INT270927 Regulation of Binding of Ppp2r1a 1 0.04 0 0.29
164 INT253646 Phosphorylation of Cd2 1 0.09 0.43 0.29
165 INT9997 Negative_regulation of Localization of IGHE 4 0.42 0.28 0.28
166 INT106782 Negative_regulation of Positive_regulation of Igh-6 2 0.42 0.93 0.28
167 INT215118 Negative_regulation of Ighg2b 2 0.30 0.93 0.28
168 INT270929 Regulation of Ppp2r1a 1 0.02 0 0.28
169 INT86183 Binding of Igha 2 0.47 1.5 0.27
170 INT173085 Binding of LILRA3 3 0.08 0.89 0.26
171 INT225076 Positive_regulation of Binding of IGHG3 2 0.50 0.92 0.26
172 INT283996 Negative_regulation of Positive_regulation of IGHG3 2 0.20 1.15 0.25
173 INT352045 Binding of Cd48 1 0.05 2.8 0.25
174 INT211181 Protein_catabolism of IGHE 1 0.07 1.28 0.25
175 INT185450 Localization of IGHG1 1 0.33 1.56 0.25
176 INT260876 Negative_regulation of IL7R 1 0.29 0.47 0.24
177 INT57545 Positive_regulation of Positive_regulation of Ighd 1 0.15 1.78 0.24
178 INT325492 Regulation of Ep300 1 0.04 0.29 0.24
179 INT32334 Regulation of LILRA3 3 0.08 0 0.23
180 INT270161 Positive_regulation of Phosphorylation of Lck 1 0.13 0.23 0.23
181 INT202028 Binding of LILRA2 1 0.35 0.38 0.23
182 INT202024 Negative_regulation of LILRA2 1 0.41 0.38 0.23
183 INT232328 Localization of Cd2 2 0.51 0 0.22
184 INT278159 Regulation of LCK 1 0.04 0.98 0.22
185 INT278161 Localization of LCK 1 0.27 0.98 0.22
186 INT206700 Binding of LAG3 1 0.23 0.7 0.21
187 INT212787 Negative_regulation of Binding of EP300 1 0.13 0.53 0.2
188 INT256666 Regulation of Gene_expression of EP300 1 0.14 0.07 0.2
189 INT256661 Regulation of Positive_regulation of EP300 1 0.23 0.07 0.2
190 INT192857 Gene_expression of Ppp2r1a 6 0.47 1.74 0.19
191 INT131159 Negative_regulation of Binding of Cd2 1 0.23 1.38 0.19
192 INT57779 Positive_regulation of Regulation of IGHE 1 0.04 1.36 0.19
193 INT325490 Positive_regulation of Ep300 1 0.03 0.22 0.19
194 INT53272 Negative_regulation of Positive_regulation of IgG-2a 1 0.10 0.19 0.18
195 INT211658 Regulation of Igj 1 0.37 0.78 0.18
196 INT76126 Transcription of IGHA1 1 0.05 0.08 0.18
197 INT272794 Positive_regulation of Positive_regulation of IGHG3 3 0.04 2.84 0.17
198 INT174526 Localization of KIR2DL3 2 0.35 0.14 0.17
199 INT41423 Gene_expression of Cd2 3 0.53 2.06 0.16
200 INT238679 Negative_regulation of Localization of Ighg1 2 0.39 0.61 0.15
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