GO:0003867

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Name 4-aminobutyrate transaminase activity
Categary Function
Go Slim No
Go Link GO:0003867
Unique Molecular Interactions 458
Total Molecular Interactions 582
Total Single Events 13010
Pain Genes Associated 2

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for 4-aminobutyrate transaminase activity. They are ordered first by their pain relevance and then by number of times they were reported for 4-aminobutyrate transaminase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT69938 Cck Positive_regulation of Localization of Abat 2 0.29 0 3.78
2 INT106338 Positive_regulation of Tacr1 Positive_regulation of Localization of Abat 5 0.34 0 3.01
3 INT69937 Cck Positive_regulation of Abat 2 0.31 0 2.88
4 INT245348 Binding of Abat and Vta1 1 0.03 0.53 2.01
5 INT34662 Abat Positive_regulation of Localization of Gnrh1 1 0.26 0 1.98
6 INT58678 Binding of Penk and Abat 2 0.40 1.39 1.97
7 INT13430 Abat Positive_regulation of Localization of Sst 2 0.33 0 1.94
8 INT145940 Binding of Gad1 and Abat 2 0.14 1.44 1.78
9 INT90658 Abat Regulation of Localization of Cck 2 0.24 0 1.64
10 INT30872 Abat Positive_regulation of Localization of Gast 1 0.26 0 1.43
11 INT10548 Nts Regulation of Localization of Abat 2 0.14 0 1.42
12 INT48881 TWIST1 Positive_regulation of Localization of Abat 1 0.02 0.44 1.29
13 INT7284 Abat Regulation of Sst 1 0.18 0 1.28
14 INT86090 SCN5A Negative_regulation of Positive_regulation of Abat 1 0.00 0 1.25
15 INT81097 Akr1d1 Regulation of Localization of Abat 1 0.00 0 1.2
16 INT34661 Abat Positive_regulation of Localization of Pomc 1 0.04 0 1.18
17 INT30871 Abat Regulation of Localization of Sst 1 0.13 0 1.17
18 INT262336 Binding of Abat and Tmem132a 1 0.00 1.39 1.14
19 INT102570 Abat Regulation of Gene_expression of Penk 3 0.13 0 1.12
20 INT223157 Abat Negative_regulation of Localization of Il6 1 0.05 1.13 1.1
21 INT53176 Spink4 Regulation of Localization of Abat 1 0.19 0 1.09
22 INT79323 Abat Regulation of Vmn2r1 1 0.00 0 1.08
23 INT53842 Abat Regulation of Gabrd 1 0.04 1 1.08
24 INT87855 Flvcr2 Positive_regulation of Localization of Abat 1 0.02 0 1.05
25 INT153963 Gatsl2 Regulation of Abat 1 0.02 0.97 1.03
26 INT104089 Vta1 Negative_regulation of Abat 1 0.14 0 1.03
27 INT75247 Abat Regulation of Gene_expression of Tacr1 1 0.23 0.41 1.03
28 INT338892 TNFSF14 Regulation of Abat 1 0.00 0.61 1.01
29 INT131173 Chrna7 Positive_regulation of Localization of Abat 1 0.10 0 1.01
30 INT338895 TNFSF14 Regulation of Regulation of Abat 1 0.00 0.62 1.01
31 INT245349 Binding of Abat and Gpr156 1 0.02 0.26 1
32 INT34660 Abat Regulation of Localization of Gnrh1 1 0.17 0 0.98
33 INT81127 Binding of Gabrd and Abat 3 0.25 0 0.96
34 INT7283 Binding of Sst and Abat 1 0.23 0 0.96
35 INT87854 Binding of Drd1a and Positive_regulation of Localization of Abat 1 0.08 0 0.96
36 INT60827 Ddc Positive_regulation of Localization of Abat 1 0.12 0.34 0.94
37 INT60828 Ddc Positive_regulation of Abat 1 0.13 0.34 0.93
38 INT60868 Abat Regulation of Localization of LH 2 0.17 0 0.92
39 INT154256 Nts Positive_regulation of Abat 1 0.10 0 0.91
40 INT90561 Slc6a1 Negative_regulation of Abat 1 0.02 0.25 0.91
41 INT78449 Abat Positive_regulation of Localization of Vip 1 0.23 0 0.89
42 INT218062 Abat Negative_regulation of Ctse 1 0.03 0.25 0.89
43 INT61698 G2e3 Regulation of Localization of Abat 1 0.05 0 0.88
44 INT154258 Binding of Abat and Prss12 1 0.03 0 0.87
45 INT90559 Gm5114 Regulation of Abat 1 0.02 0.31 0.87
46 INT90560 Gm5114 Positive_regulation of Abat 1 0.03 0.25 0.86
47 INT97913 NCOR2 Regulation of ABAT 1 0.00 0 0.85
48 INT344101 Positive_regulation of Drd1a Positive_regulation of Localization of Abat 1 0.01 0 0.84
49 INT63308 Gypc Positive_regulation of Localization of Abat 1 0.11 0 0.83
50 INT291581 Pde5a Regulation of Localization of Abat 1 0.03 0 0.83
51 INT61033 Tmem132a Positive_regulation of Abat 1 0.22 0.07 0.82
52 INT235087 NOS1 Positive_regulation of Localization of ABAT 1 0.02 0.61 0.81
53 INT245350 Abat Regulation of Dbh 1 0.00 0.37 0.8
54 INT13427 Positive_regulation of Abat Positive_regulation of Localization of Sst 1 0.33 0 0.79
55 INT87513 Binding of Tac2 and Abat 1 0.09 0.26 0.78
56 INT139409 Cck Negative_regulation of Abat 1 0.14 0.5 0.76
57 INT12448 Abat Positive_regulation of Gene_expression of Pdyn 1 0.42 0 0.76
58 INT12449 Abat Regulation of Gene_expression of Pdyn 1 0.25 0 0.76
59 INT222528 Abat Positive_regulation of Gene_expression of Gh1 1 0.01 0 0.75
60 INT292598 CNR1 Regulation of ABAT 1 0.08 0.32 0.75
61 INT292599 CNR1 Regulation of Localization of ABAT 1 0.08 0.32 0.75
62 INT98572 Binding of ABAT and CRYGS 1 0.01 0 0.75
63 INT53177 Spink4 Positive_regulation of Localization of Abat 1 0.33 0 0.74
64 INT26872 ABAT Positive_regulation of Localization of POMC 1 0.03 0 0.71
65 INT47264 Abat Regulation of Localization of Gh1 1 0.14 0 0.67
66 INT222552 Abat Regulation of Gene_expression of Gh1 1 0.00 0 0.67
67 INT132152 Adra2a Regulation of Localization of Abat 1 0.03 0 0.66
68 INT74852 Chrm1 Positive_regulation of Localization of Abat 1 0.11 0 0.66
69 INT45335 Mlst8 Positive_regulation of Localization of Abat 1 0.36 0 0.65
70 INT45334 Mlst8 Regulation of Localization of Abat 1 0.21 0 0.65
71 INT264775 Binding of Gabbr1 and Abat 1 0.03 0 0.64
72 INT98386 GAD1 Positive_regulation of Gene_expression of Abat 1 0.30 1.67 0.62
73 INT147890 Prok2 Positive_regulation of Localization of Abat 1 0.18 0.36 0.6
74 INT147891 Prokr1 Positive_regulation of Localization of Abat 1 0.05 0.36 0.6
75 INT190987 Abat Regulation of Scn2a1 1 0.03 0.07 0.59
76 INT32755 Binding of Gabrg1 and Abat 1 0.10 0 0.59
77 INT133502 Grip2 Regulation of Localization of Abat 1 0.06 0.1 0.58
78 INT61505 ABAT Negative_regulation of Localization of CRH 1 0.09 0 0.57
79 INT90657 Abat Regulation of Localization of Sct 1 0.10 0 0.55
80 INT334592 MRGPRD Positive_regulation of ABAT 1 0.03 0.32 0.54
81 INT216918 Binding of Ca2 and Abat 1 0.01 0.45 0.53
82 INT222524 Abat Negative_regulation of Localization of Trh 1 0.02 0.16 0.51
83 INT60872 Binding of ENG and Abat 1 0.00 0 0.49
84 INT243435 Slc3a1 Regulation of Negative_regulation of Abat 1 0.02 0 0.49
85 INT46051 ABAT Regulation of Localization of GH1 1 0.19 0 0.49
86 INT291580 Pde5a Regulation of Abat 1 0.04 0.39 0.48
87 INT190144 Binding of ABAT and Gabrg1 1 0.01 0 0.47
88 INT10550 Prss12 Positive_regulation of Localization of Abat 1 0.06 0 0.45
89 INT232427 ABAT Regulation of PRL 1 0.08 0.26 0.45
90 INT148635 Abat Negative_regulation of Gene_expression of Tnf 1 0.10 0.53 0.44
91 INT148634 Abat Negative_regulation of Transcription of Nos2 1 0.19 0.52 0.44
92 INT80679 Abat Regulation of Localization of Sult1b1 1 0.01 0 0.44
93 INT10549 Prss12 Regulation of Localization of Abat 1 0.04 0 0.43
94 INT347563 Abat Positive_regulation of Gopc 1 0.04 0.2 0.43
95 INT232293 Abat Regulation of Binding of Fig4 1 0.11 0 0.43
96 INT63372 Grin1 Regulation of Localization of Abat 1 0.20 0 0.43
97 INT309199 Abat Positive_regulation of Adarb1 1 0.00 0 0.42
98 INT63307 Gypc Regulation of Localization of Abat 1 0.08 0 0.42
99 INT15356 Abat Regulation of Tacr1 1 0.02 0 0.42
100 INT103346 Abat Positive_regulation of Gabrd 1 0.20 0.08 0.4
101 INT232292 Abat Positive_regulation of Fig4 1 0.12 0 0.4
102 INT67288 Binding of Insrr and Positive_regulation of Localization of Abat 1 0.00 0.18 0.37
103 INT232421 Binding of PRL and Positive_regulation of Regulation of ABAT 1 0.09 0 0.37
104 INT273982 Ascc1 Regulation of Localization of Abat 1 0.04 0 0.35
105 INT28327 Binding of Sigmar1 and Abat 1 0.15 0.14 0.35
106 INT144060 Bdnf Regulation of Regulation of Abat 1 0.14 0 0.35
107 INT273983 Abat Regulation of Gene_expression of Ascc1 1 0.07 0 0.34
108 INT232419 ABAT Positive_regulation of Localization of PRL 1 0.09 0 0.33
109 INT232425 Binding of ABAT and Positive_regulation of PRL 1 0.09 0.15 0.33
110 INT232420 PRL Positive_regulation of Regulation of ABAT 1 0.09 0 0.33
111 INT3727 Abat Regulation of LH 1 0.05 0 0.32
112 INT241971 Ca2 Regulation of Localization of Abat 1 0.01 0 0.31
113 INT3728 Abat Positive_regulation of Positive_regulation of Prl 1 0.15 0 0.31
114 INT347562 Abat Positive_regulation of Mki67 1 0.03 0 0.3
115 INT98385 Abat Negative_regulation of GAD1 1 0.24 1.28 0.3
116 INT344746 GAD1 Regulation of Gene_expression of ABAT 1 0.19 0.75 0.23
117 INT264776 Abat Positive_regulation of Gabbr1 1 0.03 0.06 0.22
118 INT273985 Ascc1 Negative_regulation of Localization of Abat 1 0.07 0 0.14
119 INT207822 ABAT Positive_regulation of Localization of GCG 1 0.02 0 0.1
120 INT344747 ABAT Positive_regulation of Gene_expression of MUC1 1 0.04 0.6 0.05
121 INT274385 Binding of ABAT and CDIPT 1 0.00 1.21 0
122 INT109169 Abat Positive_regulation of Phosphorylation of Kcnab3 1 0.01 0 0
123 INT109170 Abat Positive_regulation of Nr5a2 1 0.03 0 0
124 INT109171 Abat Positive_regulation of Phosphorylation of Nr5a2 1 0.03 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for 4-aminobutyrate transaminase activity. They are ordered first by their pain relevance and then by number of times they were reported in 4-aminobutyrate transaminase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT3439 Localization of Abat 1017 0.78 112.39 727.06
2 INT2909 Positive_regulation of Abat 334 0.70 62.1 256.43
3 INT9987 Gene_expression of Abat 296 0.78 95.46 226.34
4 INT2211 Negative_regulation of Abat 267 0.59 66.51 200.98
5 INT3440 Negative_regulation of Localization of Abat 221 0.57 33.94 180.36
6 INT2910 Regulation of Abat 169 0.62 36.95 153.53
7 INT4829 Positive_regulation of Localization of Abat 199 0.55 20.91 150.48
8 INT3441 Regulation of Localization of Abat 117 0.38 8.67 87.59
9 INT2212 Binding of Abat 89 0.48 18.36 63.99
10 INT18981 Gene_expression of ABAT 78 0.68 38.35 61.36
11 INT19488 Localization of ABAT 56 0.69 21.51 50.56
12 INT12228 Positive_regulation of Gene_expression of Abat 44 0.65 17.51 40.55
13 INT6417 Negative_regulation of ABAT 49 0.51 19.6 36.81
14 INT3913 Positive_regulation of ABAT 47 0.69 22.73 33.4
15 INT2912 Positive_regulation of Positive_regulation of Abat 29 0.66 6.48 27.54
16 INT63444 Regulation of Gene_expression of Abat 26 0.51 14.65 26.29
17 INT31874 Negative_regulation of Gene_expression of Abat 31 0.42 12.22 20.31
18 INT18621 Binding of ABAT 28 0.36 9.88 18.04
19 INT34952 Regulation of ABAT 28 0.61 6.05 14.39
20 INT64225 Positive_regulation of Localization of ABAT 15 0.60 4.46 11.28
21 INT19575 Negative_regulation of Positive_regulation of Abat 14 0.43 2.07 11.05
22 INT39016 Transcription of Abat 19 0.53 3.92 10.82
23 INT92777 Positive_regulation of Gene_expression of ABAT 13 0.44 7.49 9.27
24 INT5359 Protein_catabolism of Abat 12 0.62 5.11 8.54
25 INT52132 Positive_regulation of Negative_regulation of Abat 9 0.50 0.53 7.03
26 INT155989 Negative_regulation of Localization of ABAT 7 0.38 1.29 6.95
27 INT155988 Regulation of Localization of ABAT 5 0.24 2.19 6.59
28 INT12603 Positive_regulation of Binding of Abat 10 0.63 0.66 5.86
29 INT45824 Regulation of Positive_regulation of Abat 6 0.24 1.2 5.16
30 INT66710 Negative_regulation of Regulation of Abat 4 0.32 0.42 4.23
31 INT24746 Negative_regulation of Binding of Abat 4 0.42 0.1 3.51
32 INT98384 Negative_regulation of Negative_regulation of Abat 4 0.37 2.28 3.41
33 INT141452 Negative_regulation of Binding of ABAT 4 0.37 1.41 3.17
34 INT13033 Regulation of Negative_regulation of Abat 4 0.27 0.61 2.97
35 INT258081 Protein_catabolism of ABAT 5 0.10 2.57 2.86
36 INT21131 Negative_regulation of Gene_expression of ABAT 6 0.42 4.93 2.83
37 INT80435 Negative_regulation of Positive_regulation of ABAT 2 0.34 0.69 2.45
38 INT42307 Regulation of Binding of Abat 2 0.41 0.09 2.01
39 INT5358 Positive_regulation of Protein_catabolism of Abat 2 0.38 1.28 1.89
40 INT98091 Positive_regulation of Regulation of Abat 2 0.50 0.17 1.78
41 INT157569 Positive_regulation of Positive_regulation of ABAT 1 0.60 0.24 1.78
42 INT108078 Regulation of Regulation of Abat 2 0.30 0.95 1.64
43 INT45378 Regulation of Transcription of Abat 2 0.27 0.78 1.54
44 INT258051 Negative_regulation of Protein_catabolism of ABAT 3 0.04 1.86 1.52
45 INT114080 Negative_regulation of Negative_regulation of ABAT 3 0.38 1.53 1.47
46 INT344758 Regulation of Gene_expression of ABAT 1 0.33 1.61 1.37
47 INT45332 Negative_regulation of Protein_catabolism of Abat 2 0.37 1.06 1.09
48 INT26554 Positive_regulation of Negative_regulation of ABAT 1 0.50 0.7 0.92
49 INT95239 Negative_regulation of Transcription of Abat 1 0.14 0.05 0.67
50 INT109164 Phosphorylation of Abat 5 0.39 0 0.51
51 INT338888 Positive_regulation of Transcription of Abat 1 0.03 0.13 0.44
52 INT125552 Regulation of Positive_regulation of ABAT 1 0.27 0 0.43
53 INT292610 Negative_regulation of Transcription of ABAT 1 0.09 0.72 0.36
54 INT339362 Positive_regulation of Binding of ABAT 1 0.02 1 0.35
55 INT292605 Transcription of ABAT 1 0.15 0.71 0.32
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