GO:0003887

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Name DNA-directed DNA polymerase activity
Categary Function
Go Slim No
Go Link GO:0003887
Unique Molecular Interactions 23
Total Molecular Interactions 32
Total Single Events 183
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for DNA-directed DNA polymerase activity. They are ordered first by their pain relevance and then by number of times they were reported for DNA-directed DNA polymerase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT305851 Polk Positive_regulation of Gene_expression of Tslp 1 0.29 0.9 0.51
2 INT305853 Polk Regulation of Gene_expression of Hand2 1 0.12 0.93 0.35
3 INT305856 Polk Regulation of Gene_expression of TH1L 1 0.43 0.93 0.35
4 INT305849 Polk Positive_regulation of Gene_expression of Hand2 1 0.08 0.76 0.27
5 INT305854 Polk Regulation of Gene_expression of Atp11c 1 0.05 0.73 0.26
6 INT105542 PTGES Positive_regulation of DNTT 1 0.00 0.62 0.25
7 INT305850 Polk Positive_regulation of Gene_expression of dp 1 0.07 0.64 0.21
8 INT305848 Polk Positive_regulation of dp 1 0.09 0 0.19
9 INT305857 Polk Regulation of Gene_expression of IFN1@ 1 0.31 0.74 0.17
10 INT305846 Polk Positive_regulation of Gene_expression of Il4 1 0.13 0.24 0.15
11 INT305855 Polk Regulation of Atp11c 1 0.02 0.73 0.11
12 INT305845 Polk Positive_regulation of Regulation of Hand2 1 0.08 0.34 0
13 INT225550 Binding of Mybbp1a and Carm1 1 0.06 0 0
14 INT225521 Binding of Prmt1 and Mybbp1a 1 0.05 0 0
15 INT199733 PRB1 Regulation of REV1 1 0.01 0 0
16 INT225482 Binding of Mybbp1a and Acp5 1 0.09 0.06 0
17 INT305852 Polk Positive_regulation of Positive_regulation of Il4 1 0.13 0.08 0
18 INT276665 Binding of Lig3 and Polg 1 0.32 0 0
19 INT274387 Binding of POLA1 and IGSF9 1 0.01 0.58 0
20 INT225568 Binding of Mybbp1a and Pprc1 1 0.00 0 0
21 INT305847 Polk Positive_regulation of Hand2 1 0.09 0.34 0
22 INT251822 Binding of POLG and C10orf2 1 0.42 0.29 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for DNA-directed DNA polymerase activity. They are ordered first by their pain relevance and then by number of times they were reported in DNA-directed DNA polymerase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT49867 Negative_regulation of Polg 7 0.39 4.07 1.86
2 INT305832 Gene_expression of Polk 1 0.48 0.49 1.64
3 INT105543 Gene_expression of DNTT 11 0.65 4.63 1
4 INT17246 Negative_regulation of POLG 16 0.56 9.69 0.79
5 INT142157 Positive_regulation of Protein_catabolism of Polg 1 0.04 0.32 0.77
6 INT142156 Protein_catabolism of Polg 1 0.06 0.32 0.75
7 INT158837 Binding of POLG 4 0.37 4.69 0.44
8 INT305826 Regulation of Gene_expression of Polk 1 0.28 0 0.43
9 INT305817 Positive_regulation of Gene_expression of Polk 1 0.36 0.05 0.34
10 INT305837 Regulation of Polk 1 0.28 0 0.28
11 INT199744 Regulation of REV1 2 0.16 0.91 0.27
12 INT191460 Localization of REV1 4 0.19 1.46 0.25
13 INT105544 Positive_regulation of DNTT 1 0.00 0.62 0.25
14 INT69418 Positive_regulation of REV1 2 0.45 2.03 0.24
15 INT138715 Gene_expression of POLG 12 0.66 6.97 0.23
16 INT305841 Binding of Polk 1 0.23 0.43 0.22
17 INT169582 Phosphorylation of POLG 2 0.54 1.98 0.18
18 INT305827 Negative_regulation of Gene_expression of Polk 1 0.26 0 0.16
19 INT302679 Negative_regulation of Localization of POLG 1 0.39 0.99 0.11
20 INT302692 Localization of POLG 1 0.69 0.99 0.1
21 INT251829 Positive_regulation of POLG 1 0.53 1.5 0.08
22 INT277088 Negative_regulation of Gene_expression of DNTT 1 0.41 0.36 0.08
23 INT199746 Gene_expression of REV1 17 0.33 9.53 0.05
24 INT251827 Regulation of POLG 3 0.59 2.94 0.04
25 INT215548 Regulation of DNTT 1 0.44 0.29 0.04
26 INT276649 Gene_expression of Polg 6 0.70 1.31 0
27 INT138714 Positive_regulation of Polg 3 0.18 0.39 0
28 INT199742 Binding of REV1 3 0.18 1.33 0
29 INT225337 Gene_expression of Mybbp1a 2 0.15 0.07 0
30 INT266162 Transcription of POLG 2 0.68 0.76 0
31 INT225429 Negative_regulation of Mybbp1a 1 0.09 0 0
32 INT310442 Gene_expression of POLA1 1 0.30 0.97 0
33 INT285148 Positive_regulation of Gene_expression of REV1 1 0.12 0.57 0
34 INT177233 Binding of Mybbp1a 1 0.36 0 0
35 INT276663 Negative_regulation of Gene_expression of Polg 1 0.39 0 0
36 INT266161 Regulation of Negative_regulation of POLG 1 0.38 0.56 0
37 INT307195 Positive_regulation of Mybbp1a 1 0.09 0.24 0
38 INT266164 Negative_regulation of Gene_expression of POLG 1 0.41 1.08 0
39 INT285149 Protein_catabolism of REV1 1 0.15 0.24 0
40 INT310440 Positive_regulation of POLA1 1 0.18 0.09 0
41 INT285147 Negative_regulation of REV1 1 0.11 0.34 0
42 INT266170 Negative_regulation of Transcription of POLG 1 0.36 1.43 0
43 INT251832 Positive_regulation of Positive_regulation of POLG 1 0.35 0.28 0
44 INT276659 Positive_regulation of Gene_expression of Polg 1 0.45 0 0
45 INT310439 Regulation of POLA1 1 0.24 2.21 0
46 INT310443 Negative_regulation of POLA1 1 0.16 0.31 0
47 INT285144 Phosphorylation of REV1 1 0.18 0.31 0
48 INT285150 Negative_regulation of Gene_expression of REV1 1 0.11 1.03 0
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