GO:0003906

From wiki-pain
Jump to: navigation, search
Name DNA-(apurinic or apyrimidinic site) lyase activity
Categary Function
Go Slim No
Go Link GO:0003906
Unique Molecular Interactions 29
Total Molecular Interactions 49
Total Single Events 184
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for DNA-(apurinic or apyrimidinic site) lyase activity. They are ordered first by their pain relevance and then by number of times they were reported for DNA-(apurinic or apyrimidinic site) lyase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT253759 Hmgb1 Positive_regulation of Apex1 1 0.09 4.53 0.69
2 INT253760 Hmgb1 Positive_regulation of Gene_expression of Apex1 1 0.10 3.53 0.58
3 INT131810 Nfkb1 Negative_regulation of Localization of Apex1 1 0.01 0.52 0.57
4 INT253770 Hmgb1 Positive_regulation of Localization of Apex1 1 0.08 0.71 0.49
5 INT253766 Binding of Apex1 and Tlr4 1 0.03 0.53 0.32
6 INT253762 Binding of Apex1 and Hmgb1 1 0.09 1.29 0.32
7 INT253765 Apex1 Positive_regulation of Hmgb1 1 0.09 1.27 0.24
8 INT89763 Positive_regulation of APEX1 Positive_regulation of Positive_regulation of NR4A1 1 0.10 0.87 0.14
9 INT253764 Atp9a Positive_regulation of Apex1 1 0.00 0.39 0.08
10 INT223536 Binding of HAND1 and Hmga1 1 0.26 0.57 0.07
11 INT223531 Binding of Hmga1 and Tcf3 1 0.26 0.57 0.07
12 INT170328 Gene_expression of Ido1 Positive_regulation of Hmga2 1 0.01 0.13 0.04
13 INT287814 Apex1 Positive_regulation of Gene_expression of Rnf128 1 0.03 0.15 0.03
14 INT196948 Hmga2 Positive_regulation of Hdac1 1 0.36 0.23 0
15 INT196959 Hmga2 Positive_regulation of Localization of E2f1 1 0.54 0.24 0
16 INT286115 Binding of APEX1 and Mutyh 1 0.10 0 0
17 INT196940 Positive_regulation of Hmga2 Positive_regulation of E2f1 1 0.50 0.47 0
18 INT196961 Binding of Hmga2 and Rb1 1 0.48 6.47 0
19 INT223523 Positive_regulation of Hmga1 Positive_regulation of Erv4 1 0.21 0.95 0
20 INT217151 Gene_expression of MIR98 Negative_regulation of HMGA2 1 0.24 1.08 0
21 INT268600 Mirlet7a-1 Regulation of HMGA2 1 0.01 0.72 0
22 INT196956 Binding of Hmga2 and Hdac1 1 0.25 0.23 0
23 INT196947 Binding of Rb1 and Positive_regulation of Hmga2 1 0.50 0.3 0
24 INT196951 Hmga2 Positive_regulation of E2f1 1 0.50 0.98 0
25 INT196942 Binding of E2f1 and Hmga2 1 0.39 0.87 0
26 INT217142 MIR98 Regulation of Gene_expression of HMGA2 1 0.40 2.22 0
27 INT196953 Hmga2 Negative_regulation of Rb1 1 0.59 0.35 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for DNA-(apurinic or apyrimidinic site) lyase activity. They are ordered first by their pain relevance and then by number of times they were reported in DNA-(apurinic or apyrimidinic site) lyase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT131808 Localization of Apex1 2 0.16 13.46 4.61
2 INT34977 Gene_expression of Hmga2 11 0.76 12.39 3.07
3 INT253756 Gene_expression of Apex1 1 0.14 7.47 1.84
4 INT168167 Gene_expression of Hmga1 3 0.60 3.48 1.09
5 INT34978 Negative_regulation of Gene_expression of Hmga2 2 0.42 1.53 0.95
6 INT88987 Gene_expression of HMGA2 8 0.77 10.46 0.64
7 INT253750 Positive_regulation of Gene_expression of Apex1 1 0.10 1.43 0.64
8 INT88170 Positive_regulation of HMGA2 2 0.69 2 0.48
9 INT88167 Negative_regulation of Positive_regulation of HMGA2 1 0.41 0.16 0.35
10 INT182073 Binding of APEX1 4 0.12 1.72 0.32
11 INT88988 Positive_regulation of Gene_expression of HMGA2 1 0.69 4.05 0.29
12 INT196937 Positive_regulation of Hmga2 3 0.68 2.47 0.28
13 INT227426 Positive_regulation of Apex1 2 0.08 1.98 0.23
14 INT253752 Negative_regulation of Localization of Apex1 1 0.08 1.26 0.2
15 INT89772 Positive_regulation of APEX1 4 0.21 2.29 0.19
16 INT223502 Binding of Hmga1 1 0.27 0.96 0.13
17 INT223509 Positive_regulation of Gene_expression of Hmga1 1 0.38 0.96 0.13
18 INT182078 Gene_expression of APEX1 3 0.59 4.77 0.12
19 INT190501 Regulation of Apex1 1 0.12 0.32 0.1
20 INT273338 Protein_catabolism of Apex1 4 0.05 0.57 0.09
21 INT170298 Regulation of Gene_expression of Hmga2 1 0.01 0.48 0.08
22 INT88990 Binding of HMGA2 1 0.48 0.95 0.07
23 INT170300 Positive_regulation of Gene_expression of Hmga2 2 0.68 4.51 0.06
24 INT170302 Regulation of Hmga2 2 0.44 0.94 0.06
25 INT182080 Localization of APEX1 2 0.57 2.3 0.05
26 INT214043 Positive_regulation of Localization of APEX1 1 0.38 0.64 0.05
27 INT76371 Protein_catabolism of Hmga2 1 0.02 0.06 0.03
28 INT182079 Negative_regulation of APEX1 5 0.18 1.75 0
29 INT196931 Phosphorylation of Hmga2 1 0.80 0.4 0
30 INT196923 Binding of Hmga2 1 0.47 2.5 0
31 INT300344 Localization of HMGA2 1 0.42 1.75 0
32 INT217195 Negative_regulation of HMGA2 1 0.55 3.54 0
33 INT182075 Negative_regulation of Positive_regulation of APEX1 1 0.13 0.63 0
34 INT182072 Regulation of APEX1 1 0.08 0.76 0
35 INT196932 Negative_regulation of Binding of Hmga2 1 0.42 0.24 0
36 INT196938 Negative_regulation of Hmga2 1 0.42 0.23 0
37 INT223519 Positive_regulation of Hmga1 1 0.35 0.87 0
38 INT268581 Regulation of HMGA2 1 0.18 0.72 0
39 INT217225 Negative_regulation of Negative_regulation of HMGA2 1 0.55 2.4 0
40 INT214034 Positive_regulation of Gene_expression of APEX1 1 0.53 0.85 0
41 INT310100 Transcription of APEX1 1 0.09 0 0
42 INT196921 Localization of Hmga2 1 0.74 0.44 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox