GO:0003924

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Name GTPase activity
Categary Function
Go Slim Yes
Go Link GO:0003924
Unique Molecular Interactions 916
Total Molecular Interactions 1217
Total Single Events 8381
Pain Genes Associated 119

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for GTPase activity. They are ordered first by their pain relevance and then by number of times they were reported for GTPase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT269444 Binding of RAB5A and HHIP 1 0.04 0 5.79
2 INT103724 Oprd1 Positive_regulation of Gtpbp4 3 0.30 0.91 4.18
3 INT264929 Binding of Cnr1 and Gnaz 1 0.18 1.71 2.89
4 INT121698 HRAS Negative_regulation of Gene_expression of MMP3 1 0.06 0.5 2.6
5 INT96465 Pnoc Positive_regulation of GEM 1 0.01 0.74 2.39
6 INT133946 Binding of DNM2 and OPRK1 1 0.11 0 2.1
7 INT13940 DNM2 Regulation of Localization of CGA 1 0.11 0 1.86
8 INT134363 Prkcg Regulation of ADCY2 1 0.00 0.14 1.7
9 INT80199 Ngf Regulation of Transcription of Rab38 1 0.01 1.48 1.68
10 INT103725 Negative_regulation of Oprd1 Positive_regulation of Gtpbp4 1 0.17 0.38 1.65
11 INT103726 Regulation of Oprd1 Positive_regulation of Gtpbp4 1 0.10 0.38 1.64
12 INT317184 BMS1 Regulation of Gene_expression of NAV1 1 0.03 1.94 1.62
13 INT247281 GLC1N Negative_regulation of HRAS 1 0.02 1.98 1.62
14 INT351366 LPA Positive_regulation of Rab38 1 0.00 0.95 1.53
15 INT240057 Binding of RHOB and NME8 1 0.41 4.11 1.5
16 INT21425 Binding of Pomc and Gtpbp4 1 0.01 0.1 1.45
17 INT133933 Binding of DNM2 and TP53INP2 1 0.00 0 1.38
18 INT122659 Binding of CACNA1A and SAR1B 1 0.06 1.38 1.35
19 INT115985 Cpe Positive_regulation of Binding of Gnas 1 0.00 0.17 1.28
20 INT121464 Negative_regulation of Oprm1 Positive_regulation of Dnm2 1 0.34 0 1.26
21 INT121465 Binding of Dnm2 and Oprm1 1 0.23 0 1.24
22 INT124874 Gnat3 Positive_regulation of Localization of Calca 2 0.08 0.75 1.2
23 INT21424 Binding of Penk and Gtpbp4 1 0.02 0.16 1.2
24 INT65203 OPRL1 Negative_regulation of ADCY1 1 0.19 0 1.19
25 INT116730 Rac1 Regulation of Localization of Calca 1 0.13 1.32 1.19
26 INT49955 OPRM1 Positive_regulation of ADCY1 1 0.21 0.31 1.19
27 INT264930 Gnaz Positive_regulation of Negative_regulation of Cnr1 1 0.20 0 1.14
28 INT65204 PNOC Negative_regulation of ADCY1 1 0.07 0 1.14
29 INT117504 OPA1 Positive_regulation of CPP 1 0.09 1.09 1.13
30 INT130627 Gnas Regulation of Prkaca 1 0.00 0 1.13
31 INT264931 Binding of Gnaz and Hrh1 1 0.01 0.83 1.12
32 INT64259 Binding of Gtpbp4 and Ptprg 1 0.06 0 1.1
33 INT269443 Positive_regulation of Binding of RAB5A and HHIP 1 0.04 0 1.06
34 INT18828 DNM2 Positive_regulation of Localization of LTB4R 1 0.01 0.07 1.06
35 INT118859 GNA14 Positive_regulation of STAT3 1 0.01 0.38 1.03
36 INT224856 Binding of Bdnf and Eef2 1 0.14 0 1.02
37 INT157142 OPA1 Positive_regulation of Gene_expression of Camk2a 1 0.02 0.3 1.02
38 INT144661 Dnm1 Negative_regulation of Binding of Hbegf 1 0.24 0 1.01
39 INT53052 ANTXRL Negative_regulation of Negative_regulation of ADCY1 1 0.01 0.66 0.99
40 INT61637 Binding of P2ry2 and Gtpbp4 1 0.02 0.1 0.99
41 INT166790 HRAS Negative_regulation of Gene_expression of PTGER1 1 0.01 1.46 0.95
42 INT73466 PTPLA Positive_regulation of Transcription of Hras1 1 0.21 0.98 0.95
43 INT264926 Binding of Gnaz and Pag1 1 0.08 0.19 0.94
44 INT153685 Binding of Bcl2l11 and Gtpbp4 1 0.08 0.76 0.93
45 INT52114 Oprd1 Regulation of ADCY1 2 0.05 0.46 0.9
46 INT54200 Gnai1 Negative_regulation of Pag1 1 0.05 0.18 0.9
47 INT54197 Binding of Gnai1 and Pag1 1 0.04 0.18 0.9
48 INT53152 Rac1 Regulation of Scg2 1 0.03 0 0.9
49 INT121702 HRAS Negative_regulation of Positive_regulation of MMP1 1 0.06 0.2 0.9
50 INT121701 HRAS Negative_regulation of MMP1 1 0.06 0.2 0.89
51 INT121704 HRAS Negative_regulation of MMP3 1 0.06 0.19 0.89
52 INT53155 Rac1 Positive_regulation of Gene_expression of Calca 1 0.06 0 0.89
53 INT301079 Binding of GNAT1 and INPP5E 1 0.00 0.59 0.89
54 INT121699 HRAS Negative_regulation of Gene_expression of MMP1 1 0.06 0.19 0.88
55 INT52390 OPRD1 Regulation of ADCY1 1 0.09 0.13 0.86
56 INT114324 RAF1 Positive_regulation of Phosphorylation of ADCY6 1 0.02 0.05 0.85
57 INT124878 Gnat3 Negative_regulation of Gene_expression of FOS 1 0.09 0.16 0.85
58 INT114323 Binding of ADCY6 and RAF1 1 0.02 0.05 0.85
59 INT80877 Negative_regulation of PCDHB17 Negative_regulation of ADCY1 1 0.01 0.08 0.84
60 INT80878 PCDHB17 Negative_regulation of ADCY1 1 0.01 0.08 0.84
61 INT74383 Sst Positive_regulation of GEM 1 0.01 0.09 0.82
62 INT269455 Binding of RAB5A and GOPC 1 0.08 0 0.82
63 INT74382 Negative_regulation of Sst Positive_regulation of GEM 1 0.00 0.09 0.82
64 INT124877 Gnat3 Negative_regulation of FOS 1 0.09 0.15 0.82
65 INT124876 Gnat3 Negative_regulation of Positive_regulation of FOS 1 0.09 0.15 0.82
66 INT74384 Regulation of Sst Positive_regulation of GEM 1 0.00 0.09 0.82
67 INT80200 Negative_regulation of Ngf Negative_regulation of Gene_expression of Rab38 1 0.01 0.68 0.8
68 INT128180 Gna12 Regulation of Regulation of RHOA 1 0.00 0 0.78
69 INT142454 Npff Positive_regulation of Gtpbp4 1 0.56 0 0.78
70 INT142455 Binding of Npff and Gtpbp4 1 0.40 0 0.78
71 INT81976 Binding of GNA15 and OPRL1 1 0.02 0 0.77
72 INT118854 GNA14 Positive_regulation of Positive_regulation of STAT3 1 0.02 0.31 0.76
73 INT133935 DNM2 Positive_regulation of OPRK1 1 0.11 0 0.76
74 INT65593 CALCA Negative_regulation of Positive_regulation of ADCY1 1 0.23 0.07 0.76
75 INT162164 ARF6 Regulation of Positive_regulation of PLD2 1 0.60 0 0.74
76 INT43662 Negative_regulation of Binding of Chrna7 and Rac1 1 0.01 0 0.73
77 INT148909 Binding of GNA13 and TP53INP2 1 0.06 0.31 0.73
78 INT133943 Binding of DNM2 and OPRL1 1 0.00 0 0.73
79 INT43663 Binding of Chrna7 and Rac2 1 0.01 0 0.72
80 INT43661 Binding of Chrna7 and Rac1 1 0.01 0 0.72
81 INT162162 ARF6 Regulation of OPRM1 1 0.19 0 0.71
82 INT262574 Gnaq Positive_regulation of Prkca 1 0.00 0.57 0.71
83 INT123869 Binding of GNAS and OPRK1 1 0.00 0.37 0.7
84 INT43647 Binding of Eef1a1 and Man2a2 1 0.16 0.23 0.7
85 INT133936 Binding of DNM2 and YY1 1 0.29 0 0.69
86 INT74599 YY1 Negative_regulation of ADCY1 2 0.36 0.31 0.67
87 INT121966 HRAS Positive_regulation of RAC1 1 0.75 0.41 0.67
88 INT113931 Mors1 Positive_regulation of Gtpbp4 1 0.02 0 0.67
89 INT264927 Cnr1 Regulation of Gnaz 1 0.23 0.05 0.66
90 INT118824 OPA1 Positive_regulation of Gene_expression of Nos1 2 0.03 0.24 0.65
91 INT136815 VEGFA Positive_regulation of Positive_regulation of RHOA 1 0.44 0.06 0.65
92 INT184193 HRAS Negative_regulation of Gene_expression of IL1B 1 0.00 1.12 0.65
93 INT62849 TUBE1 Positive_regulation of Rmp1 1 0.02 0 0.65
94 INT34211 DNM2 Regulation of Localization of Crh 1 0.01 0.09 0.63
95 INT334594 Binding of GNAI1 and MRGPRD 1 0.01 0.19 0.63
96 INT36511 Binding of Htr2a and Eef1a1 1 0.22 0 0.62
97 INT330104 Binding of Sh3rf1 and Rac1 1 0.13 2.41 0.62
98 INT330101 Binding of Map3k11 and Rac1 1 0.16 2.43 0.62
99 INT247285 GLC1N Positive_regulation of Gene_expression of HRAS 1 0.02 1.3 0.61
100 INT142993 Serpinc1 Positive_regulation of Phosphorylation of RHOA 1 0.05 0.05 0.59
101 INT161387 Binding of PNOC and GTPBP4 1 0.03 1.05 0.59
102 INT41250 Binding of Adra2a and Eef1a1 1 0.06 0.4 0.56
103 INT210830 OPRM1 Negative_regulation of ADCY1 1 0.00 0.06 0.55
104 INT59635 Binding of Adarb1 and Gnaz 1 0.01 0 0.55
105 INT32908 Binding of ADCY1 and Drd2 1 0.00 0 0.54
106 INT64744 OR5D2P Negative_regulation of ADCY1 1 0.00 0 0.54
107 INT164971 Binding of Rgs7 and Gnai2 1 0.01 0 0.54
108 INT269449 Positive_regulation of Binding of RAB5A and GOPC 1 0.11 0 0.53
109 INT164970 Binding of Rgs8 and Gnai2 1 0.01 0 0.53
110 INT97949 Negative_regulation of NRP2 Negative_regulation of Positive_regulation of CDC42 1 0.06 0.72 0.51
111 INT77218 Binding of NFKBIL1 and NKIRAS2 1 0.00 0.27 0.51
112 INT182813 EEF1A2 Negative_regulation of ITGAL 1 0.10 1.53 0.51
113 INT33415 KNG1 Positive_regulation of GBP1 1 0.02 0.43 0.51
114 INT93265 Binding of ADCY1 and OPRL1 1 0.13 0.17 0.51
115 INT97953 ST3GAL3 Positive_regulation of CDC42 1 0.09 0.7 0.5
116 INT81004 Htr1a Positive_regulation of Gtpbp4 1 0.20 0 0.5
117 INT243998 Binding of Prkaca and Dnm1 1 0.11 0.24 0.49
118 INT243999 Positive_regulation of Binding of Prkaca and Dnm1 1 0.14 0.24 0.49
119 INT244000 Positive_regulation of Binding of Tfap2a and Dnm1 1 0.04 0.24 0.49
120 INT243997 Binding of Tfap2a and Dnm1 1 0.03 0.24 0.49
121 INT131508 Gene_expression of Rac1 Positive_regulation of Trpv1 1 0.42 0.21 0.48
122 INT131503 Gene_expression of Rac1 Positive_regulation of Ngf 1 0.38 0.21 0.48
123 INT155881 Binding of CDX2 and KRAS 1 0.40 1.51 0.47
124 INT89647 OPRM1 Regulation of ADCY1 1 0.09 0.09 0.47
125 INT153658 PRKCA Negative_regulation of GEM 1 0.01 0.22 0.46
126 INT95564 Positive_regulation of HRAS Positive_regulation of IL12A 1 0.03 0.7 0.45
127 INT95562 HRAS Positive_regulation of IL12A 1 0.03 0.7 0.45
128 INT95563 HRAS Positive_regulation of TNF 1 0.03 0.7 0.45
129 INT258584 ADORA3 Negative_regulation of ADCY1 1 0.02 0 0.44
130 INT111275 BRI3P1 Positive_regulation of Negative_regulation of ADCY1 1 0.06 0 0.44
131 INT148930 Rac1 Regulation of Chrna7 1 0.13 0.6 0.44
132 INT89649 INSRR Regulation of ADCY1 1 0.00 0.07 0.44
133 INT111274 C2 Positive_regulation of Negative_regulation of ADCY1 1 0.14 0 0.44
134 INT72016 Positive_regulation of Binding of Gnai2 and Ptprg 1 0.02 0 0.44
135 INT73832 Pld1 Positive_regulation of ADCY1 1 0.00 0.16 0.44
136 INT169466 TGFB3 Positive_regulation of HRAS 1 0.03 0.89 0.43
137 INT56578 Eef1a1 Positive_regulation of Localization of Gnrh1 1 0.16 0 0.43
138 INT124088 Rab38 Negative_regulation of Mapk14 1 0.00 0.89 0.42
139 INT251430 Gnat3 Positive_regulation of Gucy1b2 1 0.04 0.48 0.42
140 INT346218 Positive_regulation of Kras Positive_regulation of Phosphorylation of Mdk 1 0.01 0.71 0.42
141 INT247287 Gene_expression of GLC1N Regulation of Gene_expression of HRAS 1 0.02 0.56 0.42
142 INT40208 Binding of Eef1a1 and Hils1 1 0.01 0.22 0.42
143 INT131506 Rac1 Regulation of Positive_regulation of Mapk14 1 0.19 0.39 0.42
144 INT269448 HHIP Positive_regulation of Binding of RAB5A 1 0.04 0 0.42
145 INT131505 Rac1 Regulation of Gene_expression of Trpv1 1 0.55 0.39 0.42
146 INT146274 Binding of Rasd1 and Nos1ap 1 0.33 0.18 0.41
147 INT114516 Eef1a1 Positive_regulation of Transcription of co 1 0.00 0 0.41
148 INT146273 Binding of Nos1 and Rasd1 1 0.34 0.18 0.41
149 INT68526 Binding of ADCY1 and DIO2 1 0.01 0.07 0.41
150 INT207110 Adam3 Regulation of Gene_expression of Eef1a1 1 0.01 1 0.41
151 INT80233 Positive_regulation of OPRM1 Positive_regulation of GNAI1 1 0.23 0 0.41
152 INT72018 Binding of Gnai2 and Ptprg 1 0.01 0 0.41
153 INT68527 Binding of ADCY1 and OPRD1 1 0.06 0.07 0.41
154 INT105170 OPRD1 Positive_regulation of Phosphorylation of ADCY1 1 0.08 0 0.41
155 INT80232 OPRM1 Positive_regulation of GNAI1 1 0.23 0 0.41
156 INT11425 OR2A12 Positive_regulation of Negative_regulation of ADCY1 1 0.01 0 0.4
157 INT351237 HRAS Regulation of CBL 1 0.00 0.48 0.4
158 INT105169 RAF1 Regulation of Positive_regulation of ADCY1 1 0.12 0 0.4
159 INT124799 PRKCA Positive_regulation of Localization of ADCY6 1 0.19 0 0.4
160 INT162289 Binding of TUBA1A and Phospho2 1 0.31 1.26 0.4
161 INT56876 Regulation of Binding of Cd36 and Gtpbp4 1 0.00 0 0.4
162 INT56875 Binding of Cd36 and Gtpbp4 1 0.00 0 0.4
163 INT275156 Agt Positive_regulation of Rac1 1 0.03 2.89 0.4
164 INT162288 Regulation of Binding of TUBA1A and Phospho2 1 0.24 1.28 0.4
165 INT166788 HRAS Negative_regulation of Phosphorylation of NFKB1 1 0.08 0.5 0.39
166 INT269456 RAB5A Regulation of Binding of HHIP 1 0.04 0 0.38
167 INT180442 Acot1 Positive_regulation of Rhoa 1 0.08 1.03 0.38
168 INT104992 Ptger3 Regulation of Rab38 1 0.02 0.79 0.38
169 INT166792 Binding of CD44 and HRAS 3 0.12 1.49 0.37
170 INT300610 Rorb Regulation of Dnm2 1 0.01 0.27 0.37
171 INT300608 Arc Regulation of Dnm2 1 0.15 0.27 0.37
172 INT173356 Gnaq Positive_regulation of CDK20 1 0.06 0 0.37
173 INT26552 Gene_expression of Mras Positive_regulation of Gene_expression of KNG1 1 0.03 0.07 0.36
174 INT257741 HRAS Negative_regulation of PTEN 1 0.15 1.06 0.35
175 INT251426 Gnat3 Negative_regulation of Aldh2 1 0.22 0 0.35
176 INT257737 Positive_regulation of HRAS Negative_regulation of PTEN 1 0.17 1.07 0.35
177 INT330105 Rac1 Positive_regulation of Mapk8 1 0.15 1.47 0.34
178 INT134080 OPA1 Negative_regulation of Phosphorylation of Gnb2l1 1 0.03 0.22 0.34
179 INT88252 Binding of RAP1A and Krit1 1 0.36 2.25 0.33
180 INT20468 Ran Negative_regulation of Localization of Prl 1 0.30 0 0.33
181 INT109282 Gdi2 Negative_regulation of Gtpbp4 1 0.01 0.13 0.32
182 INT330103 Rac1 Positive_regulation of Positive_regulation of Mapk8 1 0.14 1.24 0.32
183 INT241776 Binding of AVP and Positive_regulation of ADCY1 1 0.06 0.54 0.32
184 INT295722 PTGER2 Positive_regulation of RAC1 1 0.02 2.14 0.32
185 INT330109 Binding of Racgap1 and Rac1 1 0.03 1.22 0.32
186 INT161435 OPA1 Positive_regulation of Gene_expression of Tnc 1 0.02 0.21 0.32
187 INT295725 PTGER2 Positive_regulation of RAC2 1 0.05 1.92 0.32
188 INT285567 Binding of IL1B and Cdc42 1 0.03 0.77 0.31
189 INT152061 Binding of SEPT9 and CD177 1 0.00 1.76 0.31
190 INT303105 CAMK4 Positive_regulation of Hras1 1 0.04 0.16 0.31
191 INT169612 OGFR Regulation of RAN 1 0.23 0.14 0.3
192 INT166789 HRAS Regulation of Positive_regulation of NFKB1 1 0.05 0.31 0.3
193 INT260438 Binding of Cd4 and Mx1 1 0.00 1.52 0.29
194 INT265467 HRAS Negative_regulation of Gene_expression of PTGS2 1 0.01 0.84 0.29
195 INT260434 Binding of Cd8a and Mx1 1 0.00 1.52 0.29
196 INT339001 GSX1 Positive_regulation of ADCY1 1 0.01 0 0.29
197 INT141438 Gnai2 Positive_regulation of Localization of ADCY1 1 0.01 0.43 0.29
198 INT251420 Aldh3a1 Regulation of Gene_expression of Gnat3 1 0.09 0.08 0.28
199 INT71550 GTPBP4 Regulation of Localization of INS 1 0.00 0.16 0.28
200 INT346220 Binding of Kras and Braf 1 0.03 0.58 0.28

Single Events

The table below shows the top 100 pain related interactions that have been reported for GTPase activity. They are ordered first by their pain relevance and then by number of times they were reported in GTPase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT6490 Negative_regulation of ADCY1 145 0.58 26.25 70.96
2 INT1599 Positive_regulation of ADCY1 146 0.67 30.05 64.9
3 INT9298 Positive_regulation of Gtpbp4 64 0.69 12.29 41.97
4 INT19396 Regulation of Rac1 66 0.53 37.41 30.01
5 INT47459 Gene_expression of Rac1 101 0.68 45.27 24.33
6 INT28216 Gene_expression of HRAS 173 0.75 93.97 20.78
7 INT12617 Regulation of ADCY1 41 0.61 7.38 15.94
8 INT7531 Positive_regulation of Eef1a1 29 0.62 8.16 15.41
9 INT23212 Positive_regulation of Rac1 46 0.55 32.85 15.1
10 INT49089 Gene_expression of Rab38 22 0.45 6.79 13.76
11 INT27627 Binding of Rac1 41 0.41 22.88 13.68
12 INT21421 Regulation of Gtpbp4 15 0.30 2.7 13.49
13 INT26545 Gene_expression of Hras1 173 0.78 79.54 13.21
14 INT146197 Positive_regulation of Rhoa 60 0.68 34.12 12.02
15 INT49087 Positive_regulation of Rab38 20 0.00 8.01 12
16 INT11429 Gene_expression of ADCY1 26 0.74 5.89 11.93
17 INT16659 Gene_expression of Eef1a1 34 0.64 6.1 11.85
18 INT40486 Positive_regulation of Positive_regulation of ADCY1 20 0.48 4.29 11.33
19 INT204112 Gene_expression of GEM 43 0.75 38.74 11.23
20 INT91357 Regulation of Dnm2 5 0.61 0 11.06
21 INT67915 Negative_regulation of Gtpbp4 18 0.33 6.31 10.17
22 INT12620 Negative_regulation of Negative_regulation of ADCY1 16 0.44 2.98 10.1
23 INT62919 Regulation of Gnas 22 0.43 5.61 9.55
24 INT106595 Negative_regulation of Dnm2 10 0.58 0.15 9.29
25 INT50055 Negative_regulation of Rac1 36 0.50 19.74 8.98
26 INT9968 Negative_regulation of Rab38 15 0.00 10.45 8.64
27 INT1682 Negative_regulation of Rem1 28 0.37 7.38 8.4
28 INT54681 Negative_regulation of Positive_regulation of ADCY1 16 0.38 2.7 8.14
29 INT6384 Regulation of Eef1a1 21 0.61 2.95 7.97
30 INT68434 Gene_expression of Gtpbp4 15 0.54 5.5 7.91
31 INT264910 Positive_regulation of Gnaz 1 0.30 0 7.82
32 INT14207 Gene_expression of DNM2 20 0.67 5.76 7.64
33 INT6341 Binding of Gtpbp4 11 0.44 1.54 7.3
34 INT77756 Positive_regulation of GTPBP4 16 0.11 2.6 7.29
35 INT106599 Positive_regulation of Dnm2 8 0.69 0.28 7.01
36 INT18578 Binding of Eef1a1 20 0.48 2.53 6.95
37 INT25467 Regulation of Rab38 19 0.00 8.68 6.73
38 INT234813 Gene_expression of RAB5A 58 0.66 3.67 6.48
39 INT103723 Regulation of Positive_regulation of Gtpbp4 5 0.22 1.56 6.35
40 INT11258 Gene_expression of Gnas 58 0.58 21.6 6.33
41 INT67635 Negative_regulation of Gnas 29 0.04 11.4 6.32
42 INT20899 Negative_regulation of GNAI1 12 0.57 4.24 6.07
43 INT34742 Gene_expression of Gnat3 44 0.67 6.83 5.65
44 INT69350 Gene_expression of RAC1 23 0.77 12.16 5.54
45 INT72000 Gene_expression of Gnaq 17 0.75 3.12 5.48
46 INT15367 Gene_expression of OPA1 35 0.67 24.9 5.45
47 INT80881 Phosphorylation of ADCY1 7 0.69 1.22 5.29
48 INT18577 Negative_regulation of Eef1a1 20 0.39 3.57 5.24
49 INT33854 Localization of OPA1 19 0.65 10.55 5.04
50 INT34870 Positive_regulation of OPA1 18 0.59 10.66 5
51 INT62920 Regulation of Gnai1 3 0.52 0.08 4.78
52 INT255981 Localization of RAB5A 3 0.68 0.88 4.76
53 INT269476 Binding of RAB5A 1 0.41 0 4.76
54 INT128178 Positive_regulation of RHOA 59 0.68 9.3 4.7
55 INT17391 Gene_expression of GNAI1 11 0.75 5.26 4.7
56 INT17393 Positive_regulation of GNAI1 17 0.49 2.42 4.66
57 INT88909 Positive_regulation of Gene_expression of Dnm1 6 0.70 3.43 4.59
58 INT26546 Positive_regulation of Gene_expression of Hras1 35 0.70 16.59 4.54
59 INT106596 Transcription of Dnm2 4 0.69 0 4.5
60 INT14574 Positive_regulation of Negative_regulation of ADCY1 9 0.66 2.45 4.39
61 INT96464 Positive_regulation of GEM 7 0.45 5.48 4.37
62 INT98357 Binding of Gnas 11 0.41 1.87 4.35
63 INT63113 Positive_regulation of HRAS 30 0.67 22.85 4.28
64 INT20981 Binding of HRAS 42 0.48 24.49 4.23
65 INT34624 Negative_regulation of REM1 22 0.38 9.25 4.22
66 INT34829 Positive_regulation of Gnat3 27 0.46 5.24 4.14
67 INT74203 Positive_regulation of Positive_regulation of Gtpbp4 6 0.50 0.33 4.13
68 INT32933 Gene_expression of GNAS 57 0.32 10.58 4.03
69 INT109861 Gene_expression of Rhoa 11 0.78 5.67 4.02
70 INT80175 Positive_regulation of Gene_expression of HRAS 24 0.67 14.69 3.97
71 INT169475 Localization of HRAS 14 0.73 9.02 3.9
72 INT112928 Localization of Dnm2 3 0.74 0 3.81
73 INT78619 Positive_regulation of RAC1 27 0.65 10.43 3.75
74 INT88906 Gene_expression of Dnm1 5 0.78 10.48 3.7
75 INT87408 Negative_regulation of ADCY2 3 0.01 0.1 3.68
76 INT25136 Localization of Gnat3 23 0.75 5.01 3.65
77 INT126685 Gene_expression of Rem1 30 0.65 11.21 3.61
78 INT53706 Positive_regulation of Kras 13 0.67 9.26 3.57
79 INT24883 Regulation of OPA1 14 0.45 9.73 3.44
80 INT87281 Localization of ADCY1 7 0.64 1.84 3.42
81 INT121967 Regulation of RAC1 9 0.45 6.14 3.41
82 INT106422 Negative_regulation of Gene_expression of Rac1 4 0.43 3.97 3.41
83 INT117117 Positive_regulation of REM1 12 0.40 10.1 3.33
84 INT25466 Binding of Rab38 6 0.00 2.23 3.28
85 INT139010 Regulation of Gfm1 16 0.32 5.02 3.27
86 INT137679 Localization of Gfm1 18 0.08 9.58 3.24
87 INT146194 Negative_regulation of Rhoa 21 0.42 11.05 3.22
88 INT19393 Gene_expression of Gfm1 31 0.51 18.9 3.2
89 INT58475 Localization of Rac1 12 0.75 5.94 3.2
90 INT28166 Positive_regulation of Rem1 8 0.40 7.96 3.19
91 INT317186 Regulation of BMS1 1 0.04 3.9 3.17
92 INT13179 Regulation of Positive_regulation of ADCY1 5 0.34 0.89 3.08
93 INT128179 Gene_expression of RHOA 7 0.64 2.48 3.01
94 INT301081 Positive_regulation of GNAT1 1 0.12 4.16 3
95 INT59309 Negative_regulation of Gene_expression of ADCY1 3 0.42 1.04 2.98
96 INT146191 Gene_expression of Rhoa 32 0.67 17.63 2.92
97 INT5913 Binding of OPA1 12 0.41 9.33 2.92
98 INT69641 Positive_regulation of ADCY2 5 0.32 0.18 2.87
99 INT3605 Negative_regulation of OPA1 14 0.38 10.88 2.84
100 INT109833 Binding of GNB3 7 0.48 8.83 2.84
101 INT30815 Binding of ADCY1 7 0.36 0.21 2.79
102 INT136784 Phosphorylation of Eef2 4 0.55 0 2.79
103 INT13943 Localization of DNM2 4 0.52 0.07 2.75
104 INT121463 Regulation of Localization of Dnm2 2 0.45 0 2.72
105 INT234825 Positive_regulation of Gene_expression of RAB5A 16 0.59 1.15 2.71
106 INT11196 Negative_regulation of Gnat3 26 0.37 3.14 2.69
107 INT264915 Positive_regulation of Localization of Gnaz 1 0.19 0 2.68
108 INT62683 Negative_regulation of HRAS 19 0.57 7.93 2.65
109 INT80884 Positive_regulation of Phosphorylation of ADCY1 4 0.43 0.24 2.64
110 INT11426 Positive_regulation of Gene_expression of ADCY1 5 0.29 0.68 2.63
111 INT204116 Regulation of Gene_expression of GEM 8 0.29 8.66 2.6
112 INT204110 Positive_regulation of Gene_expression of GEM 11 0.67 8.85 2.57
113 INT140363 Negative_regulation of Rhoa 7 0.58 2.49 2.47
114 INT72013 Negative_regulation of Gnai2 5 0.35 0.09 2.44
115 INT44880 Gene_expression of REM1 21 0.30 5.3 2.43
116 INT111039 Gene_expression of Kras 20 0.60 15.42 2.39
117 INT128174 Positive_regulation of Gene_expression of RHOA 7 0.36 1.5 2.36
118 INT80194 Transcription of Rab38 4 0.04 1.85 2.35
119 INT139008 Positive_regulation of Gfm1 21 0.35 7.79 2.34
120 INT65928 Positive_regulation of Gene_expression of Rac1 12 0.42 3.34 2.33
121 INT146196 Localization of Rhoa 6 0.78 4.68 2.3
122 INT131850 Gene_expression of RHOC 17 0.72 29.06 2.28
123 INT71268 Positive_regulation of Gene_expression of Eef1a1 7 0.41 1.75 2.26
124 INT71266 Regulation of Gene_expression of Eef1a1 1 0.51 0 2.2
125 INT146192 Positive_regulation of Positive_regulation of Rhoa 8 0.60 8.15 2.17
126 INT70987 Binding of RAC1 14 0.37 12.14 2.13
127 INT179311 Transcription of GNAS 2 0.10 0.67 2.08
128 INT69196 Positive_regulation of Rap1a 2 0.29 1.18 2.06
129 INT108903 Negative_regulation of GNAS 7 0.57 1.58 2.04
130 INT17390 Regulation of GNAI1 5 0.04 3.58 2.03
131 INT65993 Localization of Gnai1 1 0.46 0.08 2
132 INT112880 Positive_regulation of Gnaq 17 0.49 1.97 1.95
133 INT76993 Regulation of HRAS 8 0.60 7.81 1.95
134 INT68435 Regulation of Gene_expression of Gtpbp4 4 0.34 0.96 1.89
135 INT9297 Localization of Gtpbp4 4 0.17 0.88 1.89
136 INT25871 Negative_regulation of Gnaz 3 0.23 0 1.89
137 INT117980 Regulation of Rac1 10 0.45 3.72 1.88
138 INT126626 Positive_regulation of Rhoa 14 0.69 4.43 1.87
139 INT57618 Binding of GTPBP4 9 0.43 1.61 1.87
140 INT301080 Binding of GNAT1 1 0.10 2.04 1.85
141 INT146193 Negative_regulation of Positive_regulation of Rhoa 3 0.42 3 1.84
142 INT240058 Gene_expression of RHOB 2 0.55 4.29 1.84
143 INT85348 Localization of RHOA 12 0.59 4.81 1.83
144 INT17387 Gene_expression of Gnaz 3 0.50 0.4 1.81
145 INT6628 Transcription of Eef1a1 4 0.16 2.59 1.8
146 INT136782 Positive_regulation of Phosphorylation of Eef2 1 0.41 0 1.78
147 INT163157 Binding of BMS1 3 0.42 3.6 1.77
148 INT128168 Positive_regulation of Gna12 1 0.01 0 1.76
149 INT134991 Regulation of Rem1 4 0.28 3.45 1.71
150 INT25192 Positive_regulation of Gene_expression of GNAI1 5 0.49 1.08 1.7
151 INT234827 Positive_regulation of RAB5A 3 0.59 0.54 1.69
152 INT109975 Positive_regulation of Kras 14 0.45 12.72 1.68
153 INT96823 Positive_regulation of Positive_regulation of GTPBP4 3 0.05 0.41 1.67
154 INT32939 Positive_regulation of Positive_regulation of Eef1a1 2 0.19 0 1.67
155 INT80195 Regulation of Gene_expression of Rab38 2 0.04 2.23 1.66
156 INT174656 Binding of NCF1 5 0.37 6.46 1.65
157 INT111886 Gene_expression of Dnm2 3 0.69 0.91 1.65
158 INT87289 Positive_regulation of Localization of ADCY1 3 0.43 0.36 1.65
159 INT136786 Regulation of Eef2 3 0.61 0 1.64
160 INT31616 Protein_catabolism of DNM2 5 0.75 1.61 1.63
161 INT110189 Regulation of Gnaq 3 0.02 0.26 1.63
162 INT168681 Gene_expression of BMS1 5 0.37 2.7 1.62
163 INT94827 Gene_expression of HBS1L 24 0.67 26.11 1.61
164 INT145201 Negative_regulation of Binding of Rab38 1 0.37 0.06 1.61
165 INT240059 Binding of RHOB 7 0.48 3.96 1.59
166 INT6438 Positive_regulation of RAN 6 0.42 2.09 1.59
167 INT80890 Negative_regulation of Phosphorylation of ADCY1 2 0.36 0.24 1.57
168 INT71999 Negative_regulation of Gene_expression of Gnaq 3 0.41 0.08 1.56
169 INT72310 Regulation of Regulation of ADCY1 6 0.24 1.24 1.55
170 INT128170 Gene_expression of Gna12 1 0.01 0 1.54
171 INT93624 Negative_regulation of Kras 3 0.41 1.15 1.52
172 INT9953 Positive_regulation of Gnas 10 0.34 3.21 1.51
173 INT146190 Negative_regulation of Localization of Rhoa 4 0.42 1.64 1.5
174 INT72008 Gene_expression of Gnai2 4 0.38 0.42 1.49
175 INT104694 Positive_regulation of Localization of TUBA4A 1 0.00 2.71 1.49
176 INT113785 Negative_regulation of Eef1a2 15 0.31 1.33 1.48
177 INT317187 Positive_regulation of BMS1 1 0.04 0.98 1.48
178 INT121347 Binding of GNAS 8 0.13 3.99 1.47
179 INT54190 Binding of Gnai1 2 0.34 0.28 1.47
180 INT184206 Protein_catabolism of HRAS 22 0.66 7.86 1.46
181 INT94639 Negative_regulation of Gene_expression of Gnai1 1 0.02 0.08 1.46
182 INT18493 Localization of Eef1a1 4 0.70 0.18 1.45
183 INT254072 Gene_expression of SEPT5 23 0.16 8.29 1.43
184 INT117148 Gene_expression of Eef1a1 6 0.07 2.32 1.42
185 INT58930 Negative_regulation of RAC1 14 0.55 7.55 1.4
186 INT162308 Phosphorylation of GNAS 3 0.01 1.71 1.4
187 INT15990 Binding of Gfm1 10 0.31 8.53 1.37
188 INT6706 Phosphorylation of GBP1 3 0.59 0.37 1.37
189 INT242902 Gene_expression of NCF1 12 0.78 9.34 1.36
190 INT131848 Positive_regulation of Gene_expression of RHOC 9 0.64 15.43 1.36
191 INT69195 Negative_regulation of Rap1a 1 0.10 0.34 1.33
192 INT264906 Localization of Gnaz 1 0.28 0 1.33
193 INT92383 Gene_expression of KRAS 38 0.65 32.94 1.32
194 INT148562 Positive_regulation of GNAS 13 0.16 5.31 1.32
195 INT264899 Positive_regulation of Positive_regulation of Gnaz 1 0.19 0 1.32
196 INT79099 Negative_regulation of Positive_regulation of Gtpbp4 4 0.20 0.06 1.31
197 INT229794 Positive_regulation of RAB7A 2 0.65 11.68 1.31
198 INT106598 Regulation of Regulation of Dnm2 1 0.44 0 1.31
199 INT54587 Positive_regulation of Hras1 12 0.27 5.54 1.3
200 INT146659 Negative_regulation of Negative_regulation of Rab38 1 0.00 0.45 1.3
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