GO:0003937

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Name IMP cyclohydrolase activity
Categary Function
Go Slim No
Go Link GO:0003937
Unique Molecular Interactions 21
Total Molecular Interactions 24
Total Single Events 34
Pain Genes Associated 2

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for IMP cyclohydrolase activity. They are ordered first by their pain relevance and then by number of times they were reported for IMP cyclohydrolase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT187522 ATIC Negative_regulation of Gene_expression of Nos2 1 0.02 1.46 0.7
2 INT239500 Binding of Aes and Atic 1 0.20 0.4 0.56
3 INT187519 ATIC Negative_regulation of Gene_expression of Ros1 1 0.00 1.48 0.39
4 INT187521 ATIC Positive_regulation of Prkag1 1 0.01 1.07 0.37
5 INT187518 Positive_regulation of ATIC Positive_regulation of Prkag1 1 0.01 0.99 0.25
6 INT329226 Negative_regulation of ATIC Positive_regulation of Psmd9 1 0.01 0.58 0.04
7 INT253413 ATIC Positive_regulation of Gene_expression of Prkaa2 1 0.02 0 0.04
8 INT329229 ATIC Positive_regulation of Tpt1 1 0.01 0.58 0.04
9 INT329230 Negative_regulation of ATIC Positive_regulation of Trp53 1 0.00 0.58 0.04
10 INT253417 ATIC Positive_regulation of Prkaa2 1 0.02 0.31 0.04
11 INT329231 ATIC Positive_regulation of Psmd9 1 0.01 0.58 0.04
12 INT329228 ATIC Positive_regulation of Trp53 1 0.01 0.58 0.04
13 INT329227 Negative_regulation of ATIC Positive_regulation of Tpt1 1 0.01 0.58 0.04
14 INT187520 ATIC Positive_regulation of Phosphorylation of Prkag1 1 0.01 0 0.03
15 INT253415 ATIC Regulation of Phosphorylation of Prkaa2 1 0.03 0 0.03
16 INT253418 ATIC Regulation of Prkaa2 1 0.02 0 0.03
17 INT253416 ATIC Negative_regulation of Phosphorylation of Eif4ebp1 1 0.00 0 0.03
18 INT253411 ATIC Negative_regulation of Eif4ebp1 1 0.00 0 0.03
19 INT253412 ATIC Negative_regulation of Rps6kb1 1 0.02 0 0.03
20 INT253410 ATIC Regulation of Lep 1 0.03 0.7 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for IMP cyclohydrolase activity. They are ordered first by their pain relevance and then by number of times they were reported in IMP cyclohydrolase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT187492 Positive_regulation of ATIC 9 0.05 1.74 1.88
2 INT187489 Localization of ATIC 1 0.07 4.03 1.81
3 INT187494 Gene_expression of ATIC 6 0.06 5.45 1.27
4 INT239499 Positive_regulation of Positive_regulation of ATIC 1 0.05 0.53 0.77
5 INT187491 Phosphorylation of ATIC 6 0.07 1.67 0.49
6 INT168045 Negative_regulation of ATIC 3 0.10 1.2 0.48
7 INT187490 Regulation of ATIC 1 0.04 0 0.11
8 INT187493 Binding of ATIC 1 0.04 0.07 0.08
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