GO:0003941

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Name L-serine ammonia-lyase activity
Categary Function
Go Slim No
Go Link GO:0003941
Unique Molecular Interactions 50
Total Molecular Interactions 90
Total Single Events 564
Pain Genes Associated 4

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for L-serine ammonia-lyase activity. They are ordered first by their pain relevance and then by number of times they were reported for L-serine ammonia-lyase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT281382 FSCN1 Positive_regulation of Sds 1 0.02 0.84 1.33
2 INT147033 Positive_regulation of Binding of Sds and Accn3 1 0.13 0.73 1.23
3 INT147032 Binding of Sds and Accn3 1 0.09 0.73 1.22
4 INT288323 Glyr1 Regulation of Sds 1 0.05 0.2 0.72
5 INT288326 Sds Positive_regulation of Glyr1 1 0.10 0.12 0.68
6 INT288324 Sds Positive_regulation of Gene_expression of Glyr1 1 0.10 0.12 0.68
7 INT146375 Sds Negative_regulation of Positive_regulation of Cysltr1 1 0.02 0.32 0.67
8 INT281374 Tcf21 Positive_regulation of Gene_expression of Sds 1 0.03 0 0.51
9 INT265015 Pgr Positive_regulation of Sds 1 0.04 0.49 0.37
10 INT288325 Binding of Glyr1 and Sds 1 0.07 0 0.3
11 INT63988 Cntf Regulation of Positive_regulation of Sds 1 0.22 0 0.28
12 INT76865 Lmo4 Positive_regulation of Sds 1 0.02 0.38 0.2
13 INT76866 Negative_regulation of Lmo4 Positive_regulation of Sds 1 0.02 0.38 0.2
14 INT178704 GOPC Positive_regulation of Srr 1 0.02 0 0.16
15 INT178703 Regulation of GOPC Positive_regulation of Srr 1 0.02 0 0.16
16 INT292328 Binding of Sds and Mb 1 0.11 0.24 0.1
17 INT251389 Binding of Gabbr1 and Sds 1 0.23 0.32 0.1
18 INT283352 Binding of Srr and Bsn 1 0.14 0 0.08
19 INT292334 Binding of Sds and Fig4 1 0.02 0.07 0.05
20 INT204387 Binding of Napa and Sds 1 0.00 0 0.05
21 INT283344 Regulation of Binding of Srr and Bsn 1 0.08 0 0.04
22 INT226813 Binding of Srr and Positive_regulation of IFN1@ 1 0.33 0.82 0.03
23 INT283360 Binding of Ctbp2 and Srr 1 0.10 0 0.03
24 INT283346 Binding of Srr and Kif3a 1 0.17 0 0
25 INT283358 Binding of Srr and Erc1 1 0.00 0.07 0
26 INT283349 Srr Positive_regulation of Gene_expression of Erc1 1 0.26 0 0
27 INT283353 Srr Positive_regulation of Rims2 1 0.14 0 0
28 INT292329 Binding of Sds and LOC360919 1 0.01 0.08 0
29 INT347353 Binding of Ldha and Sds 1 0.12 0.07 0
30 INT283357 Srr Positive_regulation of Rims1 1 0.12 0 0
31 INT283350 Srr Positive_regulation of Gene_expression of Rims2 1 0.14 0 0
32 INT283356 Srr Positive_regulation of Gene_expression of Rims1 1 0.12 0 0
33 INT283351 Binding of Srr and Fig4 1 0.04 0 0
34 INT347352 Negative_regulation of Binding of Ldha and Sds 1 0.14 0.07 0
35 INT283355 Srr Positive_regulation of Erc1 1 0.11 0 0
36 INT283343 Binding of Srr and Pclo 1 0.05 0 0
37 INT283347 Binding of Srr and Ctbp1 1 0.13 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for L-serine ammonia-lyase activity. They are ordered first by their pain relevance and then by number of times they were reported in L-serine ammonia-lyase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT19948 Gene_expression of Sds 34 0.63 14.69 15.44
2 INT3969 Positive_regulation of Sds 27 0.69 7.52 12.31
3 INT53685 Regulation of Sds 10 0.39 5.39 7.22
4 INT29845 Positive_regulation of Sds 11 0.62 3.69 6.63
5 INT93387 Gene_expression of Sds 9 0.65 2.58 5.72
6 INT1317 Negative_regulation of Sds 23 0.48 6.97 5.03
7 INT35990 Negative_regulation of Sds 8 0.49 4.47 4.96
8 INT131176 Gene_expression of Srr 8 0.64 3.29 4.81
9 INT35992 Regulation of Sds 7 0.52 1.14 4.04
10 INT131178 Positive_regulation of Srr 4 0.56 4.78 3.91
11 INT35634 Positive_regulation of Gene_expression of Sds 10 0.37 3.23 3.69
12 INT153108 Transcription of Srr 4 0.57 1.41 2.38
13 INT281368 Regulation of Gene_expression of Sds 3 0.13 1.66 2.31
14 INT131177 Regulation of Gene_expression of Srr 3 0.51 0.4 2.22
15 INT265010 Negative_regulation of Gene_expression of Sds 4 0.20 1.07 1.69
16 INT131179 Positive_regulation of Gene_expression of Srr 4 0.57 0.87 1.63
17 INT153106 Regulation of Transcription of Srr 1 0.37 0 1.25
18 INT76864 Negative_regulation of Positive_regulation of Sds 2 0.43 0.62 1.21
19 INT153111 Positive_regulation of Transcription of Srr 2 0.41 1.41 1.15
20 INT126706 Transcription of Sds 3 0.36 0.59 1.14
21 INT251387 Binding of Sds 1 0.27 0.46 1.12
22 INT72526 Regulation of Regulation of Sds 1 0.26 0.78 1.1
23 INT152919 Localization of Sds 2 0.42 0.69 0.83
24 INT91744 Positive_regulation of Positive_regulation of Sds 1 0.22 0.17 0.59
25 INT265007 Positive_regulation of Phosphorylation of Sds 1 0.30 0.52 0.54
26 INT265009 Phosphorylation of Sds 1 0.36 0.51 0.53
27 INT152918 Transcription of Sds 1 0.33 0.49 0.53
28 INT63985 Negative_regulation of Negative_regulation of Sds 2 0.40 0.8 0.48
29 INT265005 Localization of Sds 4 0.35 1.15 0.47
30 INT196697 Binding of Srr 13 0.22 8.01 0.45
31 INT265008 Regulation of Transcription of Sds 1 0.20 0.23 0.44
32 INT41270 Localization of Srr 4 0.68 2.08 0.39
33 INT178687 Regulation of Srr 2 0.19 0.07 0.32
34 INT121077 Binding of Sds 20 0.25 1.41 0.28
35 INT63987 Regulation of Positive_regulation of Sds 1 0.41 0 0.28
36 INT226794 Gene_expression of Srr 4 0.40 0.52 0.24
37 INT226797 Positive_regulation of Srr 3 0.30 1.05 0.08
38 INT226796 Transcription of Srr 1 0.41 0.22 0.08
39 INT226798 Negative_regulation of Binding of Srr 1 0.25 0.32 0.08
40 INT225962 Regulation of Srr 1 0.02 0.22 0.07
41 INT251378 Negative_regulation of Binding of Sds 1 0.24 0 0.07
42 INT288314 Regulation of Gene_expression of Sds 1 0.28 0 0.06
43 INT226795 Negative_regulation of Srr 2 0.25 0.94 0.04
44 INT283337 Phosphorylation of Srr 1 0.37 0 0
45 INT347351 Negative_regulation of Binding of Sds 1 0.20 0.07 0
46 INT345394 Binding of Srr 1 0.27 0 0
47 INT328748 Positive_regulation of Binding of Sds 1 0.25 0.16 0
48 INT268247 Regulation of Binding of Srr 1 0.14 0.91 0
49 INT288318 Positive_regulation of Gene_expression of Sds 1 0.36 0 0
50 INT292351 Regulation of Binding of Sds 1 0.13 0 0
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