GO:0004012

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Name phospholipid-translocating ATPase activity
Categary Function
Go Slim No
Go Link GO:0004012
Unique Molecular Interactions 52
Total Molecular Interactions 71
Total Single Events 697
Pain Genes Associated 10

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for phospholipid-translocating ATPase activity. They are ordered first by their pain relevance and then by number of times they were reported for phospholipid-translocating ATPase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT136129 Calca Positive_regulation of ATP8A2 1 0.38 0.89 2.4
2 INT197051 Binding of HLA-E and ATP8A1 1 0.00 6.52 1.14
3 INT125626 Binding of Calca and Atp8a2 1 0.00 0.4 0.76
4 INT105809 ATP8A2 Positive_regulation of P2RX2 1 0.13 0.11 0.7
5 INT116369 Binding of Calca and Atp8a2 1 0.02 0.38 0.56
6 INT17308 Ifng Positive_regulation of Atp8a1 1 0.64 0.45 0.41
7 INT172094 Binding of Atp9a and Il27ra 1 0.01 0.98 0.4
8 INT172095 Binding of Atp9a and Trav6-3 1 0.03 0.98 0.39
9 INT305854 Polk Regulation of Gene_expression of Atp11c 1 0.05 0.73 0.26
10 INT144800 Binding of TRPV1 and ATP8A2 1 0.22 0.14 0.23
11 INT167561 TRAP Positive_regulation of ATP8A2 1 0.17 0.56 0.23
12 INT115356 Binding of HLA-G and ATP8A1 1 0.00 0.52 0.15
13 INT347638 Negative_regulation of Binding of Atp9a and Hdac4 1 0.01 0.97 0.14
14 INT347639 Binding of Atp9a and Hdac4 1 0.01 0.97 0.14
15 INT65560 Binding of Atp9b and ANGPTL5 2 0.10 0.34 0.13
16 INT210861 Abca4 Positive_regulation of AGRP 1 0.00 0 0.12
17 INT305855 Polk Regulation of Atp11c 1 0.02 0.73 0.11
18 INT277692 Binding of Atp9a and Tnfrsf10b 1 0.00 1.47 0.1
19 INT235964 Binding of Atp9a and Aqp4 1 0.01 0.55 0.08
20 INT335444 Binding of Atp8a2 and Trpv1 1 0.01 0.4 0.08
21 INT253764 Atp9a Positive_regulation of Apex1 1 0.00 0.39 0.08
22 INT205537 ATP8A2 Negative_regulation of Negative_regulation of RHOXF2 1 0.01 0 0.07
23 INT328145 H2-Q13 Positive_regulation of Atp10a 1 0.54 1.23 0.07
24 INT328144 H2-Q13 Positive_regulation of Gene_expression of Atp10a 1 0.54 1.23 0.07
25 INT348690 Atp9a Positive_regulation of Gene_expression of Fgf2 1 0.00 0.21 0.05
26 INT348694 Atp9a Negative_regulation of Serpine1 1 0.00 0.24 0.03
27 INT233397 Binding of ABCA4 and COL2A1 1 0.38 3.59 0.03
28 INT331324 Binding of HLA-G and Atp8a1 1 0.03 0.16 0.03
29 INT348691 Atp9a Positive_regulation of Plau 1 0.00 0.31 0.03
30 INT298054 Binding of Atp9a and Bpifa2 1 0.00 0.33 0
31 INT196954 Binding of Atp8a1 and E2f1 1 0.40 0.49 0
32 INT348693 Atp9a Positive_regulation of Fgf2 1 0.00 0.07 0
33 INT320767 Atp11c Negative_regulation of Dsg1a 1 0.05 1.71 0
34 INT320771 Atp11c Regulation of Localization of Dsg1a 1 0.03 1.46 0
35 INT342432 Binding of Rhoa and Positive_regulation of Atp9a 1 0.20 0 0
36 INT298051 Binding of Atp9a and Vip 1 0.00 0 0
37 INT280138 Binding of NOVA2 and Atp9a 1 0.00 1.32 0
38 INT258923 Binding of CD8A and Atp8a1 1 0.23 0.07 0
39 INT65561 Binding of VWF and Atp9b 1 0.22 0.34 0
40 INT81743 Tgfb1 Negative_regulation of Gene_expression of Atp9a 1 0.00 0.21 0
41 INT328142 Binding of Atp10a and Snrpn 1 0.30 0.3 0
42 INT109766 Binding of B4GALNT1 and ATP8A2 1 0.00 0.18 0
43 INT348692 Atp9a Positive_regulation of Gene_expression of Mmp9 1 0.00 0.07 0
44 INT348695 Atp9a Positive_regulation of Mmp9 1 0.00 0.07 0
45 INT278219 CIITA Positive_regulation of Gene_expression of Atp9a 1 0.00 0.1 0
46 INT300891 Binding of Atp9a and Tgm2 1 0.00 0.39 0
47 INT278215 Ciita Positive_regulation of Gene_expression of Atp9a 1 0.11 0.1 0
48 INT336781 Negative_regulation of ERAP2 Negative_regulation of Atp8a1 1 0.48 0.31 0
49 INT320769 Atp11c Regulation of Dsg1a 1 0.05 5.87 0
50 INT300892 Binding of Atp8a1 and Tgm2 1 0.01 0.68 0
51 INT300890 Binding of Atp9a and Cd79a 1 0.00 0 0
52 INT189107 Binding of Atp8a1 and Tap1 1 0.39 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for phospholipid-translocating ATPase activity. They are ordered first by their pain relevance and then by number of times they were reported in phospholipid-translocating ATPase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT12922 Gene_expression of Atp9a 115 0.75 50.95 17.01
2 INT116367 Binding of Atp8a2 33 0.28 6.42 13.3
3 INT125624 Gene_expression of Atp8a2 12 0.15 3.91 4.85
4 INT26229 Positive_regulation of ATP8A2 6 0.67 2.1 4.48
5 INT170455 Gene_expression of Atp8a1 66 0.75 24.63 3.94
6 INT328127 Gene_expression of Atp10a 1 0.75 6.42 3.67
7 INT12923 Negative_regulation of Atp9a 17 0.35 7.87 3.52
8 INT102741 Gene_expression of Atp9b 20 0.75 8.01 3.34
9 INT81280 Binding of Atp9a 20 0.47 11.14 3.24
10 INT221097 Negative_regulation of Atp8a1 15 0.57 10.52 2.65
11 INT162682 Phosphorylation of Atp9a 1 0.80 0 2.57
12 INT27114 Gene_expression of Atp11c 20 0.42 22.22 2.37
13 INT101432 Positive_regulation of Gene_expression of Atp9a 13 0.10 7.86 1.95
14 INT51000 Positive_regulation of Atp9a 12 0.49 5.63 1.93
15 INT116368 Localization of Atp8a2 4 0.07 1.43 1.66
16 INT101431 Negative_regulation of Gene_expression of Atp9a 12 0.06 4.64 1.57
17 INT82866 Localization of Atp9a 13 0.78 6.95 1.56
18 INT24414 Negative_regulation of ATP8A2 5 0.43 1.63 1.46
19 INT259459 Positive_regulation of Atp8a2 3 0.01 1.64 1.34
20 INT141082 Transcription of Atp9a 6 0.15 3.56 1.26
21 INT92331 Gene_expression of ATP8A2 6 0.75 2.99 1.21
22 INT24416 Localization of ATP8A2 4 0.73 2.21 1.2
23 INT101433 Regulation of Gene_expression of Atp9a 7 0.10 5.77 1.13
24 INT191145 Positive_regulation of Gene_expression of Atp8a1 14 0.67 5.24 1.02
25 INT219993 Regulation of Gene_expression of Atp9b 1 0.44 2.3 0.96
26 INT20352 Binding of ATP8A2 3 0.35 1.01 0.89
27 INT17302 Positive_regulation of Atp8a1 7 0.49 2.56 0.78
28 INT125625 Positive_regulation of Binding of Atp8a2 1 0.00 0.36 0.69
29 INT102738 Binding of Atp9b 4 0.36 1.65 0.68
30 INT20213 Binding of Atp11c 6 0.08 2.11 0.66
31 INT262633 Negative_regulation of Gene_expression of Atp8a1 7 0.57 2.52 0.65
32 INT81075 Negative_regulation of Atp9b 7 0.57 1.39 0.64
33 INT147063 Negative_regulation of Atp11c 3 0.06 2.28 0.61
34 INT292065 Negative_regulation of Binding of Atp8a2 1 0.01 0.57 0.58
35 INT197512 Gene_expression of ABCA4 19 0.75 7.08 0.57
36 INT96907 Positive_regulation of ABCA4 16 0.49 4.59 0.52
37 INT45201 Negative_regulation of ABCA4 6 0.42 4.02 0.51
38 INT78592 Positive_regulation of Atp9b 4 0.49 1.54 0.44
39 INT61149 Regulation of Atp11c 1 0.11 1.67 0.43
40 INT219991 Negative_regulation of Gene_expression of Atp9b 2 0.41 0.9 0.41
41 INT9344 Regulation of Atp9a 6 0.28 1.74 0.37
42 INT210831 Gene_expression of Abca4 7 0.67 1.69 0.32
43 INT210836 Localization of Abca4 1 0.00 0 0.32
44 INT81174 Regulation of Atp9b 1 0.30 0 0.28
45 INT130293 Negative_regulation of Gene_expression of ATP8A2 1 0.42 0.8 0.26
46 INT187459 Positive_regulation of Positive_regulation of Atp9a 1 0.07 0.71 0.24
47 INT186624 Localization of Atp8a1 5 0.73 1.06 0.22
48 INT67962 Protein_catabolism of ATP8A2 1 0.64 0.7 0.22
49 INT219986 Positive_regulation of Gene_expression of Atp9b 1 0.49 0.54 0.22
50 INT300326 Transcription of Atp9b 7 0.12 0.39 0.2
51 INT102742 Positive_regulation of Binding of Atp9b 1 0.49 0.38 0.2
52 INT354927 Positive_regulation of Gene_expression of ATP8A2 1 0.02 1.39 0.19
53 INT328124 Negative_regulation of Gene_expression of Atp10a 1 0.41 0 0.17
54 INT71436 Negative_regulation of Gene_expression of Atp11c 1 0.23 1.87 0.17
55 INT71437 Positive_regulation of Gene_expression of Atp11c 2 0.27 5.63 0.16
56 INT24413 Negative_regulation of Localization of ATP8A2 1 0.42 0.08 0.16
57 INT276766 Negative_regulation of ATP8A1 1 0.01 1.76 0.16
58 INT328137 Positive_regulation of Gene_expression of Atp10a 1 0.49 0.49 0.15
59 INT259458 Positive_regulation of Gene_expression of Atp8a2 1 0.01 0.51 0.14
60 INT328125 Localization of Atp10a 1 0.73 0.09 0.13
61 INT334565 Localization of Atp9b 1 0.01 0 0.13
62 INT27117 Transcription of Atp11c 2 0.06 1.09 0.12
63 INT129426 Transcription of ATP8A2 1 0.23 0.24 0.12
64 INT189093 Binding of Atp8a1 10 0.47 2.6 0.11
65 INT37060 Transcription of Atp8a1 4 0.67 2.39 0.11
66 INT259460 Negative_regulation of Atp8a2 1 0.01 0.51 0.11
67 INT178185 Regulation of Atp8a1 2 0.44 1.7 0.1
68 INT115357 Positive_regulation of ATP8A1 1 0.01 0.55 0.1
69 INT342408 Positive_regulation of Binding of Atp9a 1 0.49 0 0.1
70 INT114084 Binding of ATP8A1 1 0.01 0.42 0.1
71 INT233399 Binding of ABCA4 9 0.46 9.49 0.07
72 INT186637 Regulation of ABCA4 3 0.37 2.02 0.07
73 INT210832 Positive_regulation of Abca4 1 0.01 0 0.06
74 INT305839 Regulation of Gene_expression of Atp11c 1 0.03 0.44 0.06
75 INT213403 Positive_regulation of Positive_regulation of ABCA4 1 0.08 0.5 0.04
76 INT339976 Positive_regulation of Transcription of Atp8a1 1 0.49 0.6 0.04
77 INT197511 Localization of ABCA4 3 0.68 1.47 0.03
78 INT191143 Regulation of Gene_expression of Atp8a1 3 0.60 0.94 0
79 INT197513 Transcription of ABCA4 2 0.43 0.86 0
80 INT213395 Positive_regulation of Gene_expression of ABCA4 2 0.41 1.22 0
81 INT300332 Regulation of Transcription of Atp9b 1 0.06 0 0
82 INT320756 Localization of Atp11c 1 0.07 0.78 0
83 INT183492 Positive_regulation of Atp11c 1 0.06 0 0
84 INT300331 Positive_regulation of Transcription of Atp9b 1 0.11 0.09 0
85 INT83729 Gene_expression of ATP8A1 1 0.01 0 0
86 INT328128 Protein_catabolism of Atp10a 1 0.86 0 0
87 INT336758 Protein_catabolism of Atp8a1 1 0.64 0 0
88 INT328130 Regulation of Gene_expression of Atp10a 1 0.44 0.23 0
89 INT339975 Positive_regulation of Negative_regulation of Atp8a1 1 0.49 1.28 0
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