GO:0004029

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Name aldehyde dehydrogenase (NAD) activity
Categary Function
Go Slim No
Go Link GO:0004029
Unique Molecular Interactions 86
Total Molecular Interactions 120
Total Single Events 589
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for aldehyde dehydrogenase (NAD) activity. They are ordered first by their pain relevance and then by number of times they were reported for aldehyde dehydrogenase (NAD) activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT128293 Negative_regulation of Aldh1a1 Positive_regulation of Insr 1 0.00 0.99 3.34
2 INT128294 Aldh1a1 Positive_regulation of Insr 1 0.00 0.99 3.33
3 INT199189 Binding of Aldh2 and Ros1 1 0.06 0.3 0.88
4 INT17726 Positive_regulation of Binding of AKR1A1 and Aldh2 1 0.11 0.35 0.41
5 INT17725 Binding of AKR1A1 and Aldh2 1 0.08 0.35 0.4
6 INT285598 Maoa Negative_regulation of Aldh3a1 1 0.01 0.18 0.36
7 INT251426 Gnat3 Negative_regulation of Aldh2 1 0.22 0 0.35
8 INT199194 Ros1 Negative_regulation of Aldh2 1 0.07 0.27 0.3
9 INT199190 Ros1 Positive_regulation of Aldh2 1 0.08 0.27 0.3
10 INT251420 Aldh3a1 Regulation of Gene_expression of Gnat3 1 0.09 0.08 0.28
11 INT108769 Phb2 Positive_regulation of Aldh3a1 1 0.08 0.08 0.19
12 INT353489 Negative_regulation of Aldh2 Negative_regulation of Prkag1 1 0.00 0.84 0.07
13 INT251427 Gnat3 Positive_regulation of Aldh2 1 0.26 0 0.05
14 INT291749 ALDOA Regulation of ALDH2 1 0.04 0 0.05
15 INT291750 ALDOA Positive_regulation of ALDH2 1 0.08 0 0.05
16 INT342222 Gene_expression of TRNAI1 Negative_regulation of Gene_expression of Aldh2 1 0.02 0.19 0.05
17 INT330424 Binding of Aldh2 and Aldh1b1 1 0.22 0.65 0.04
18 INT342220 TRNAI1 Negative_regulation of Aldh3a1 1 0.01 0.34 0.04
19 INT291782 Binding of ALDH2 and Gnat3 1 0.12 0 0.04
20 INT251425 Aldh2 Negative_regulation of Negative_regulation of Gnat3 1 0.19 0 0.04
21 INT291781 Regulation of Binding of ALDH2 and Gnat3 1 0.11 0 0.04
22 INT206849 ESR1 Regulation of Gene_expression of ALDH1A1 1 0.11 2.26 0.04
23 INT330425 Gene_expression of Aldh2 Negative_regulation of Zmat3 1 0.00 0.64 0.04
24 INT342226 TRNAI1 Negative_regulation of Gene_expression of Aldh3a1 1 0.02 0.34 0.04
25 INT199196 Gnat3 Positive_regulation of Aldh2 2 0.26 1.06 0.03
26 INT330426 Pcyt2 Regulation of Gene_expression of Aldh2 1 0.09 0.46 0.03
27 INT291756 ALDH2 Positive_regulation of ALDOA 1 0.06 0 0.03
28 INT206895 Binding of ESR1 and Aldh1a1 1 0.03 0 0
29 INT251419 Positive_regulation of Aldh2 Positive_regulation of Gnat3 1 0.20 0 0
30 INT235303 Aldh1a1 Positive_regulation of Cpa1 1 0.17 0.4 0
31 INT330432 ALDOA Positive_regulation of Binding of Aldh2 1 0.03 0.43 0
32 INT291753 ALDOA Positive_regulation of ALDH1A1 1 0.00 0 0
33 INT291787 Gnat3 Negative_regulation of ALDH2 1 0.11 0 0
34 INT251423 Gnat3 Regulation of Binding of Aldh3a1 1 0.09 0 0
35 INT291752 Binding of ALDH2 and SGCB 1 0.08 0 0
36 INT291754 ALDOA Negative_regulation of ALDH2 1 0.07 0 0
37 INT330428 Gnat3 Negative_regulation of Aldh2 1 0.11 0.44 0
38 INT323590 Binding of Aldh2 and Napa 1 0.01 0.16 0
39 INT251418 Gnat3 Regulation of Aldh2 1 0.12 0 0
40 INT235304 Binding of Aldh1a1 and Cpa1 1 0.12 0.86 0
41 INT251429 Aldh2 Positive_regulation of Gnat3 1 0.20 0 0
42 INT330434 ALDOA Positive_regulation of Aldh2 1 0.03 0.38 0
43 INT291791 ALDH2 Negative_regulation of Gnat3 1 0.15 0.06 0
44 INT330431 Binding of ALDOA and Aldh2 1 0.03 0 0
45 INT323591 Negative_regulation of Binding of Aldh2 and Napa 1 0.02 0.17 0
46 INT251421 Binding of Gnat3 and Positive_regulation of Gene_expression of Aldh2 1 0.20 0 0
47 INT206843 Binding of ALDH1A1 and ESR1 1 0.07 0 0
48 INT251428 Aldh2 Negative_regulation of Gnat3 1 0.19 0 0
49 INT251422 Binding of Aldh2 and Gnat3 1 0.19 0 0
50 INT235305 Binding of Aldh3a1 and Cpa1 1 0.12 0.86 0
51 INT291785 ALDH2 Regulation of Localization of Gnat3 1 0.11 0 0
52 INT291790 Negative_regulation of Binding of ALDH2 and Gnat3 1 0.11 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for aldehyde dehydrogenase (NAD) activity. They are ordered first by their pain relevance and then by number of times they were reported in aldehyde dehydrogenase (NAD) activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT158864 Negative_regulation of Aldh2 25 0.58 10.92 3.81
2 INT17716 Gene_expression of Aldh2 14 0.77 4.38 3.61
3 INT81871 Positive_regulation of Aldh3a1 17 0.69 3.15 3.12
4 INT199173 Gene_expression of Aldh2 25 0.77 14.1 2.12
5 INT28926 Negative_regulation of Aldh2 11 0.58 1.25 1.97
6 INT158339 Gene_expression of ALDH2 18 0.78 4.48 1.65
7 INT158340 Negative_regulation of ALDH2 13 0.58 2.76 1.64
8 INT35492 Negative_regulation of Aldh3a1 7 0.46 1.34 1.59
9 INT147754 Binding of ALDH2 7 0.35 3.31 1.41
10 INT330414 Positive_regulation of Gene_expression of Aldh2 11 0.69 8.58 1.09
11 INT35491 Regulation of Aldh3a1 4 0.61 0.63 1.08
12 INT81868 Positive_regulation of Aldh2 14 0.69 6.61 0.97
13 INT199179 Negative_regulation of Gene_expression of Aldh2 6 0.43 3.55 0.97
14 INT17718 Positive_regulation of Gene_expression of Aldh2 3 0.50 0.96 0.94
15 INT22662 Negative_regulation of Aldh3a1 8 0.41 4.68 0.8
16 INT160477 Positive_regulation of ALDH2 3 0.49 0.49 0.72
17 INT291769 Positive_regulation of Gene_expression of ALDH2 2 0.69 2.48 0.65
18 INT28254 Gene_expression of Aldh3a1 5 0.59 3.92 0.61
19 INT195976 Gene_expression of Aldh1a1 26 0.75 14.23 0.6
20 INT38755 Regulation of Aldh1a1 3 0.44 2.14 0.55
21 INT158341 Negative_regulation of Gene_expression of ALDH2 3 0.58 0.98 0.53
22 INT227080 Regulation of ALDH2 1 0.43 0.35 0.53
23 INT81869 Negative_regulation of Positive_regulation of Aldh3a1 1 0.44 0.48 0.47
24 INT206880 Gene_expression of ALDH1A1 5 0.45 5.02 0.45
25 INT17717 Positive_regulation of Aldh2 2 0.46 0.35 0.45
26 INT81870 Binding of Aldh3a1 1 0.27 0.47 0.45
27 INT86006 Gene_expression of Aldh1a1 5 0.53 3.22 0.43
28 INT285601 Positive_regulation of Negative_regulation of Aldh3a1 1 0.06 0.22 0.3
29 INT22661 Positive_regulation of Aldh3a1 2 0.67 1.32 0.29
30 INT199186 Binding of Aldh2 5 0.37 2.58 0.28
31 INT251413 Regulation of Aldh2 1 0.41 0.06 0.27
32 INT251416 Positive_regulation of Regulation of Aldh2 1 0.46 0.06 0.27
33 INT251417 Binding of Aldh2 1 0.30 0.06 0.25
34 INT251408 Positive_regulation of Binding of Aldh2 1 0.40 0.06 0.25
35 INT115308 Positive_regulation of Gene_expression of Aldh3a1 1 0.38 0 0.24
36 INT330417 Negative_regulation of Positive_regulation of Aldh2 2 0.37 0.76 0.22
37 INT344918 Regulation of Aldh1a1 1 0.43 0.69 0.2
38 INT199178 Positive_regulation of Negative_regulation of Aldh2 2 0.50 0.98 0.18
39 INT199184 Regulation of Negative_regulation of Aldh2 1 0.32 0.44 0.18
40 INT310378 Regulation of Gene_expression of ALDH2 1 0.27 0.47 0.15
41 INT164318 Localization of ALDH2 2 0.81 0.21 0.14
42 INT81867 Positive_regulation of Positive_regulation of Aldh2 1 0.04 0.19 0.12
43 INT330412 Localization of Aldh2 1 0.74 1.3 0.12
44 INT330418 Negative_regulation of Negative_regulation of Aldh2 1 0.42 0.54 0.12
45 INT330420 Phosphorylation of Aldh2 1 0.70 0.5 0.12
46 INT199182 Transcription of Aldh2 1 0.38 0 0.1
47 INT81873 Positive_regulation of Aldh1a1 1 0.15 0.13 0.06
48 INT251414 Positive_regulation of Negative_regulation of Aldh2 1 0.42 0 0.05
49 INT251411 Positive_regulation of Positive_regulation of Aldh2 1 0.46 0 0.05
50 INT235295 Gene_expression of Aldh3a1 13 0.73 6.68 0.04
51 INT251410 Positive_regulation of Binding of Aldh3a1 1 0.19 0 0.04
52 INT206879 Positive_regulation of Gene_expression of ALDH1A1 1 0.25 1.32 0.03
53 INT251415 Localization of Aldh2 1 0.68 0 0.03
54 INT206871 Regulation of Gene_expression of ALDH1A1 1 0.23 1.32 0.03
55 INT206873 Negative_regulation of Gene_expression of ALDH1A1 1 0.34 1.3 0.03
56 INT235289 Negative_regulation of Gene_expression of Aldh3a1 3 0.40 1.65 0
57 INT235284 Positive_regulation of Gene_expression of Aldh3a1 2 0.44 2.32 0
58 INT86007 Transcription of Aldh1a1 2 0.54 1.41 0
59 INT251409 Negative_regulation of Gene_expression of Aldh3a1 1 0.20 0 0
60 INT235278 Negative_regulation of Binding of Aldh1a1 1 0.41 0.69 0
61 INT235263 Positive_regulation of Aldh1a1 1 0.49 0.44 0
62 INT291763 Positive_regulation of Positive_regulation of ALDH2 1 0.47 0 0
63 INT291774 Negative_regulation of Binding of ALDH2 1 0.40 0 0
64 INT235281 Localization of Aldh1a1 1 0.68 0.75 0
65 INT199175 Regulation of Aldh2 1 0.28 0.11 0
66 INT235279 Negative_regulation of Gene_expression of Aldh1a1 1 0.57 0.66 0
67 INT235264 Binding of Aldh1a1 1 0.36 0.69 0
68 INT235283 Protein_catabolism of Aldh3a1 1 0.83 0.42 0
69 INT235273 Regulation of Gene_expression of Aldh1a1 1 0.44 0.52 0
70 INT291762 Positive_regulation of Binding of ALDH2 1 0.47 0 0
71 INT251412 Negative_regulation of Negative_regulation of Aldh3a1 1 0.20 0 0
72 INT235274 Regulation of Gene_expression of Aldh3a1 1 0.42 1.23 0
73 INT330415 Regulation of Localization of Aldh2 1 0.45 0.67 0
74 INT235266 Positive_regulation of Transcription of Aldh1a1 1 0.49 0.92 0
75 INT199181 Regulation of Regulation of Aldh2 1 0.28 0.06 0
76 INT235293 Transcription of Aldh1a1 1 0.67 0.92 0
77 INT86005 Positive_regulation of Transcription of Aldh1a1 1 0.39 0.86 0
78 INT235288 Negative_regulation of Aldh1a1 1 0.57 3.49 0
79 INT199176 Regulation of Gene_expression of Aldh2 1 0.28 0 0
80 INT291772 Negative_regulation of Positive_regulation of ALDH2 1 0.40 0 0
81 INT235286 Protein_catabolism of Aldh1a1 1 0.86 0.47 0
82 INT235267 Positive_regulation of Gene_expression of Aldh1a1 1 0.67 3.95 0
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